Anna Klemm
Bioinformatician at Department of Information Technology; Vi3; Image Analysis
- E-mail:
- anna.klemm@it.uu.se
- Visiting address:
- Hus 10, Regementsvägen 10
- Postal address:
- Box 337
751 05 UPPSALA
- Academic merits:
- Docent
Short presentation
I am heading the BioImage Informatics Facility (BIIF), SciLifeLab/NBIS. BIIF provides the support and training to perform state-of-the-art analyses on image data. Our experts can help deploy computational methods using computer vision, machine learning, and bioinformatics to analyze images.
More information: https://www.scilifelab.se/facilities/bioimage-informatics/
Keywords
- light microscopy
- cell biology
- bioimage analysis
- quantitative biology
Biography
I received my PhD degree in cellular Biophysics at the University Erlangen-Nürnberg, Germany in 2010. I then pursued my postdoctoral work at the Max-Planck-Institute for Cell Biology and Genetic in Dresden, Germany, where I studied mitotic chromosome movements using microscopy and image analysis. From 2015-2018 I worked as a microscopist and bioimage analyst at the Core Facility BioImaging at the Biomedical Center in Munich, Germany. Since March 2018 I am working at the BioImage Informatics Facility of SciLifeLab.

Publications
Selection of publications
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A method for Boolean analysis of protein interactions at a molecular level
Part of Nature Communications, 2022
- DOI for A method for Boolean analysis of protein interactions at a molecular level
- Download full text (pdf) of A method for Boolean analysis of protein interactions at a molecular level
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Spatial Statistics for Understanding Tissue Organization
Part of Frontiers in Physiology, 2022
- DOI for Spatial Statistics for Understanding Tissue Organization
- Download full text (pdf) of Spatial Statistics for Understanding Tissue Organization
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Part of Journal of Pathology, p. 4-11, 2022
- DOI for Automated detection of vascular remodeling in human tumor draining lymph nodes by the deep learning tool HEV-finder
- Download full text (pdf) of Automated detection of vascular remodeling in human tumor draining lymph nodes by the deep learning tool HEV-finder
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A Hitchhiker's guide through the bio‐image analysis software universe
Part of FEBS Letters, p. 2472-2485, 2022
- DOI for A Hitchhiker's guide through the bio‐image analysis software universe
- Download full text (pdf) of A Hitchhiker's guide through the bio‐image analysis software universe
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Deep Learning in Image Cytometry: A Review
Part of Cytometry Part A, p. 366-380, 2019
- DOI for Deep Learning in Image Cytometry: A Review
- Download full text (pdf) of Deep Learning in Image Cytometry: A Review
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Part of Molecular Biology of the Cell, p. 1332-1345, 2018
Recent publications
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Part of Cell Communication and Signaling, 2026
- DOI for In situ mapping of activated PDGFRβ defines a prognostic discrepancy between histological subtypes of NSCLC
- Download full text (pdf) of In situ mapping of activated PDGFRβ defines a prognostic discrepancy between histological subtypes of NSCLC
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The crucial role of bioimage analysts in scientific research and publication
Part of Journal of Cell Science, 2024
- DOI for The crucial role of bioimage analysts in scientific research and publication
- Download full text (pdf) of The crucial role of bioimage analysts in scientific research and publication
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Part of Heliyon, 2023
- DOI for TissUUmaps 3: Improvements in interactive visualization, exploration, and quality assessment of large-scale spatial omics data
- Download full text (pdf) of TissUUmaps 3: Improvements in interactive visualization, exploration, and quality assessment of large-scale spatial omics data
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Visualization and quality control tools for large-scale multiplex tissue analysis in TissUUmaps3
Part of Biological Imaging, 2023
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A method for Boolean analysis of protein interactions at a molecular level
Part of Nature Communications, 2022
- DOI for A method for Boolean analysis of protein interactions at a molecular level
- Download full text (pdf) of A method for Boolean analysis of protein interactions at a molecular level
All publications
Articles in journal
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Part of Cell Communication and Signaling, 2026
- DOI for In situ mapping of activated PDGFRβ defines a prognostic discrepancy between histological subtypes of NSCLC
- Download full text (pdf) of In situ mapping of activated PDGFRβ defines a prognostic discrepancy between histological subtypes of NSCLC
-
The crucial role of bioimage analysts in scientific research and publication
Part of Journal of Cell Science, 2024
- DOI for The crucial role of bioimage analysts in scientific research and publication
- Download full text (pdf) of The crucial role of bioimage analysts in scientific research and publication
-
Part of Heliyon, 2023
- DOI for TissUUmaps 3: Improvements in interactive visualization, exploration, and quality assessment of large-scale spatial omics data
- Download full text (pdf) of TissUUmaps 3: Improvements in interactive visualization, exploration, and quality assessment of large-scale spatial omics data
-
Visualization and quality control tools for large-scale multiplex tissue analysis in TissUUmaps3
Part of Biological Imaging, 2023
-
A method for Boolean analysis of protein interactions at a molecular level
Part of Nature Communications, 2022
- DOI for A method for Boolean analysis of protein interactions at a molecular level
- Download full text (pdf) of A method for Boolean analysis of protein interactions at a molecular level
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Part of Frontiers in cell and developmental biology, 2022
- DOI for SLC38A10 Regulate Glutamate Homeostasis and Modulate the AKT/TSC2/mTOR Pathway in Mouse Primary Cortex Cells
- Download full text (pdf) of SLC38A10 Regulate Glutamate Homeostasis and Modulate the AKT/TSC2/mTOR Pathway in Mouse Primary Cortex Cells
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Part of Journal of Pathology, p. 4-11, 2022
- DOI for Automated detection of vascular remodeling in human tumor draining lymph nodes by the deep learning tool HEV-finder
- Download full text (pdf) of Automated detection of vascular remodeling in human tumor draining lymph nodes by the deep learning tool HEV-finder
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ImageJ and CellProfiler: Complements in Open‐Source Bioimage Analysis
Part of Current protocols, 2021
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Machine learning for cell classification and neighborhood analysis in glioma tissue
Part of Cytometry Part A, p. 1176-1186, 2021
- DOI for Machine learning for cell classification and neighborhood analysis in glioma tissue
- Download full text (pdf) of Machine learning for cell classification and neighborhood analysis in glioma tissue
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Part of F1000 Research, p. 334-334, 2021
- DOI for Highlights from the 2016-2020 NEUBIAS training schools for Bioimage Analysts: a success story and key asset for analysts and life scientists
- Download full text (pdf) of Highlights from the 2016-2020 NEUBIAS training schools for Bioimage Analysts: a success story and key asset for analysts and life scientists
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Bioimage analysis workflows: community resources to navigate through a complex ecosystem
Part of F1000 Research, p. 320-320, 2021
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TrackMate - My Favorite Image Analysis Tool, by Neubias Members
Part of Imaging & Microscopy, 2020
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Automated identification of the mouse brain’s spatial compartments from in situ sequencing data
Part of BMC Biology, 2020
- DOI for Automated identification of the mouse brain’s spatial compartments from in situ sequencing data
- Download full text (pdf) of Automated identification of the mouse brain’s spatial compartments from in situ sequencing data
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Part of Molecular and Cellular Biochemistry, p. 41-51, 2019
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Tracking Microscope Performance: A Workflow to Compare Point Spread Function Evaluations Over Time
Part of Microscopy and Microanalysis, p. 699-704, 2019
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Part of Molecular Biology of the Cell, p. 1332-1345, 2018
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Pumilio2-deficient mice show a predisposition for epilepsy.
Part of Disease Models and Mechanisms, p. 1333-1342, 2017
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Overlap microtubules link sister k-fibres and balance the forces on bi-oriented kinetochores.
Part of Nature Communications, 2016
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Part of Scientific Reports, 2016
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Pivoting of microtubules around the spindle pole accelerates kinetochore capture.
Part of Nature Cell Biology, p. 82-7, 2013
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Focal adhesion kinase stabilizes the cytoskeleton.
Part of Biophysical Journal, p. 2131-8, 2011
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The influence of Pyk2 on the mechanical properties in fibroblasts.
Part of Biochemical and Biophysical Research Communications - BBRC, p. 694-7, 2010
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Part of Biochemical and Biophysical Research Communications - BBRC, p. 799-801, 2009
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Thermodynamic evidence of non-muscle myosin II-lipid-membrane interaction.
Part of Biochemical and Biophysical Research Communications - BBRC, p. 500-5, 2008
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CapZ-lipid membrane interactions: a computer analysis.
Part of Theoretical Biology and Medical Modelling, 2006
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Mechano-chemical signaling in F9 cells.
Part of Cell Biology International, p. 755-9, 2006
Articles, review/survey
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Spatial Statistics for Understanding Tissue Organization
Part of Frontiers in Physiology, 2022
- DOI for Spatial Statistics for Understanding Tissue Organization
- Download full text (pdf) of Spatial Statistics for Understanding Tissue Organization
-
A Hitchhiker's guide through the bio‐image analysis software universe
Part of FEBS Letters, p. 2472-2485, 2022
- DOI for A Hitchhiker's guide through the bio‐image analysis software universe
- Download full text (pdf) of A Hitchhiker's guide through the bio‐image analysis software universe
-
Deep Learning in Image Cytometry: A Review
Part of Cytometry Part A, p. 366-380, 2019
- DOI for Deep Learning in Image Cytometry: A Review
- Download full text (pdf) of Deep Learning in Image Cytometry: A Review