Pengwei Xing

RAS pathway mutations orchestrate chromatin reconfiguration and transcriptional rewiring in colorectal cancer

Gao, Zhangjingyi; Kundu, Snehangshu; Xing, Pengwei; Cruz Davila, Eric et al.

Part of Cell Communication and Signaling, 2026

• DOI for RAS pathway mutations orchestrate chromatin reconfiguration and transcriptional rewiring in colorectal cancer
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SHP2 negatively regulates TGF-β signaling by destabilizing the TGF-β type I receptor

Zhao, Cen; Yakymovych, Ihor; Yakymovych, Mariya; Xing, Pengwei et al.

Part of Cell Communication and Signaling, 2026

• DOI for SHP2 negatively regulates TGF-β signaling by destabilizing the TGF-β type I receptor
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scFFPE-ATAC enables high-throughput single cell chromatin accessibility profiling in formalin-fixed paraffin-embedded samples

Yadav, Ram Prakash; Xing, Pengwei; Zhao, Miao; Hollander, Peter et al.

Part of Nature Communications, 2025

• DOI for scFFPE-ATAC enables high-throughput single cell chromatin accessibility profiling in formalin-fixed paraffin-embedded samples
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Genome-wide DNA methylation-analysis of blastic plasmacytoid dendritic cell neoplasm identifies distinct molecular features

Kuenstner, Axel; Schwarting, Julian; Witte, Hanno M.; Xing, Pengwei et al.

Part of Leukemia, p. 1086-1098, 2024

• DOI for Genome-wide DNA methylation-analysis of blastic plasmacytoid dendritic cell neoplasm identifies distinct molecular features
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Genomic and Epigenomic Profiling of Cancer

Xing, Pengwei

2024

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RAS pathway mutations orchestrate chromatin reconfiguration and transcriptional rewiring in colorectal cancer

Gao, Zhangjingyi; Kundu, Snehangshu; Xing, Pengwei; Cruz Davila, Eric et al.

Part of Cell Communication and Signaling, 2026

• DOI for RAS pathway mutations orchestrate chromatin reconfiguration and transcriptional rewiring in colorectal cancer
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SHP2 negatively regulates TGF-β signaling by destabilizing the TGF-β type I receptor

Zhao, Cen; Yakymovych, Ihor; Yakymovych, Mariya; Xing, Pengwei et al.

Part of Cell Communication and Signaling, 2026

• DOI for SHP2 negatively regulates TGF-β signaling by destabilizing the TGF-β type I receptor
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scFFPE-ATAC enables high-throughput single cell chromatin accessibility profiling in formalin-fixed paraffin-embedded samples

Yadav, Ram Prakash; Xing, Pengwei; Zhao, Miao; Hollander, Peter et al.

Part of Nature Communications, 2025

• DOI for scFFPE-ATAC enables high-throughput single cell chromatin accessibility profiling in formalin-fixed paraffin-embedded samples
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Genome-wide DNA methylation-analysis of blastic plasmacytoid dendritic cell neoplasm identifies distinct molecular features

Kuenstner, Axel; Schwarting, Julian; Witte, Hanno M.; Xing, Pengwei et al.

Part of Leukemia, p. 1086-1098, 2024

• DOI for Genome-wide DNA methylation-analysis of blastic plasmacytoid dendritic cell neoplasm identifies distinct molecular features
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Cutaneous squamous cell carcinoma-derived extracellular vesicles exert an oncogenic role by activating cancer-associated fibroblasts

Li, Chen; Sun, Chengxi; Lohcharoenkal, Warangkana; Ali, Mohamad Moustafa et al.

Part of Cell Death Discovery, 2023

• DOI for Cutaneous squamous cell carcinoma-derived extracellular vesicles exert an oncogenic role by activating cancer-associated fibroblasts
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FFPE-ATAC: A Highly Sensitive Method for Profiling Chromatin Accessibility in Formalin-Fixed Paraffin-Embedded Samples

Yadav, Ram Prakash; Polavarapu, Vamsi Krishna; Xing, Pengwei; Chen, Xingqi

Part of Current Protocols, 2022

• DOI for FFPE-ATAC: A Highly Sensitive Method for Profiling Chromatin Accessibility in Formalin-Fixed Paraffin-Embedded Samples
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Profiling chromatin accessibility in formalin-fixed paraffin-embedded samples

Zhang, Hua; Polavarapu, Vamsi Krishna; Xing, Pengwei; Zhao, Miao et al.

Part of Genome Research, p. 150-161, 2022

• DOI for Profiling chromatin accessibility in formalin-fixed paraffin-embedded samples
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Cell-lineage controlled epigenetic regulation in glioblastoma stem cells determines functionally distinct subgroups and predicts patient survival

Lu, Xi; Maturi, Naga Prathyusha; Jarvius, Malin; Yildirim, Irem et al.

Part of Nature Communications, 2022

• DOI for Cell-lineage controlled epigenetic regulation in glioblastoma stem cells determines functionally distinct subgroups and predicts patient survival
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A Highly Sensitive Method to Efficiently Profile the Histone Modifications of FFPE Samples

Zhao, Linxuan; Polavarapu, Vamsi Krishna; Yadav, Ram Prakash; Xing, Pengwei et al.

Part of Bio-protocol, 2022

• DOI for A Highly Sensitive Method to Efficiently Profile the Histone Modifications of FFPE Samples

FACT-seq: profiling histone modifications in formalin-fixed paraffin-embedded samples with low cell numbers

Zhao, Linxuan; Xing, Pengwei; Polavarapu, Vamsi Krishna; Zhao, Miao et al.

Part of Nucleic Acids Research, 2021

• DOI for FACT-seq: profiling histone modifications in formalin-fixed paraffin-embedded samples with low cell numbers
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The Thioesterase ACOT1 as a Regulator of Lipid Metabolism in Type 2 Diabetes Detected in a Multi-Omics Study of Human Liver

Cavalli, Marco; Diamanti, Klev; Dang, Yonglong; Xing, Pengwei et al.

Part of Omics, p. 652-659, 2021

• DOI for The Thioesterase ACOT1 as a Regulator of Lipid Metabolism in Type 2 Diabetes Detected in a Multi-Omics Study of Human Liver
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Focal amplifications are associated with chromothripsis events and diverse prognoses in gastric cardia adenocarcinoma

Zhao, Xue-Ke; Xing, Pengwei; Song, Xin; Zhao, Miao et al.

Part of Nature Communications, 2021

• DOI for Focal amplifications are associated with chromothripsis events and diverse prognoses in gastric cardia adenocarcinoma
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Genomic and Epigenomic Profiling of Cancer

Xing, Pengwei

2024

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HER2 Prognostic Significance and Therapeutic Implications in Gastric Cardia Adenocarcinoma: Insights from Multi-Omics Profiling

Wang, Lidong; Xing, Pengwei; Zhao, Xueke; Song, Xin et al.

Enhancer signatures define glioblastoma stem cell subtypes 1 with divergent patient survival

Xing, Pengwei; Neves, Ines; Salehi, Maede; Yadav, Ram Prakash et al.

Paired glioblastoma cell cultures of the fluorescent bulk tumor and non-fluorescent tumor margin display differential phenotypes and cell states across patients

Neves, Inês; Lu, Xi; Maturi, Nagaprathyusha; Dang, Yonglong et al.