Suparna Sanyal

Structural mechanism of FusB-mediated rescue from fusidic acid inhibition of protein synthesis

González-López, Adrián; Ge, Xueliang; Larsson, Daniel S.D.; Sihlbom Wallem, Carina et al.

Part of Nature Communications, 2025

• DOI for Structural mechanism of FusB-mediated rescue from fusidic acid inhibition of protein synthesis
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Structural mechanism of FusB-mediated rescue from fusidic acid inhibition of protein synthesis

González-López, Adrián; Ge, Xueliang; Larsson, Daniel; Sihlbom Wallem, Carina et al.

Part of Nature Communications, 2025

• DOI for Structural mechanism of FusB-mediated rescue from fusidic acid inhibition of protein synthesis

Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane

González-López, Adrián; Larsson, Daniel S. D.; Koripella, Ravi Kiran; Cain, Brett N. et al.

Part of Scientific Reports, 2024

• DOI for Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane
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Second messenger c-di-AMP regulates multiple antibiotic sensitivity pathways in Mycobacterium smegmatis by discrete mechanisms

Pal, Aditya Kumar; Ghorai, Dipankar; Ge, Xueliang; Sarkar, Biplab et al.

Part of FEMS Microbiology Letters, 2024

• DOI for Second messenger c-di-AMP regulates multiple antibiotic sensitivity pathways in Mycobacterium smegmatis by discrete mechanisms

Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome

Seely, Savannah M.; Parajuli, Narayan P.; De Tarafder, Arindam; Ge, Xueliang et al.

Part of Nature Communications, 2023

• DOI for Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome
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Structural mechanism of FusB-mediated rescue from fusidic acid inhibition of protein synthesis

González-López, Adrián; Ge, Xueliang; Larsson, Daniel S.D.; Sihlbom Wallem, Carina et al.

Part of Nature Communications, 2025

• DOI for Structural mechanism of FusB-mediated rescue from fusidic acid inhibition of protein synthesis
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Structural mechanism of FusB-mediated rescue from fusidic acid inhibition of protein synthesis

González-López, Adrián; Ge, Xueliang; Larsson, Daniel; Sihlbom Wallem, Carina et al.

Part of Nature Communications, 2025

• DOI for Structural mechanism of FusB-mediated rescue from fusidic acid inhibition of protein synthesis

Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane

González-López, Adrián; Larsson, Daniel S. D.; Koripella, Ravi Kiran; Cain, Brett N. et al.

Part of Scientific Reports, 2024

• DOI for Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane
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Second messenger c-di-AMP regulates multiple antibiotic sensitivity pathways in Mycobacterium smegmatis by discrete mechanisms

Pal, Aditya Kumar; Ghorai, Dipankar; Ge, Xueliang; Sarkar, Biplab et al.

Part of FEMS Microbiology Letters, 2024

• DOI for Second messenger c-di-AMP regulates multiple antibiotic sensitivity pathways in Mycobacterium smegmatis by discrete mechanisms

Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome

Seely, Savannah M.; Parajuli, Narayan P.; De Tarafder, Arindam; Ge, Xueliang et al.

Part of Nature Communications, 2023

• DOI for Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome
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Antibiotic thermorubin tethers ribosomal subunits and impedes A-site interactions to perturb protein synthesis in bacteria

Parajuli, Narayan Prasad; Emmerich, Andrew G; Mandava, Chandra Sekhar; Pavlov, Michael Y. et al.

Part of Nature Communications, 2023

• DOI for Antibiotic thermorubin tethers ribosomal subunits and impedes A-site interactions to perturb protein synthesis in bacteria
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Lamotrigine compromises the fidelity of initiator tRNA recruitment to the ribosomal P-site by IF2 and the RbfA release from 30S ribosomes in Escherichia coli

Singh, Sudhir; Lahry, Kuldeep; Mandava, Chandra Sekhar; Singh, Jitendra et al.

Part of RNA Biology, p. 681-692, 2023

• DOI for Lamotrigine compromises the fidelity of initiator tRNA recruitment to the ribosomal P-site by IF2 and the RbfA release from 30S ribosomes in Escherichia coli
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Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis

Majumdar, Soneya; Emmerich, Andrew G; Krakovka, Sascha; Mandava, Chandra Sekhar et al.

Part of Nucleic Acids Research, p. 3436-3451, 2023

• DOI for Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis
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Real-time measurements of aminoglycoside effects on protein synthesis in live cells

Aguirre Rivera, Javier; Larsson, Jimmy; Volkov, Ivan; Seefeldt, A. Carolin et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, 2021

• DOI for Real-time measurements of aminoglycoside effects on protein synthesis in live cells
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Optimization of a fluorescent-mRNA based real-time assay for precise kinetic measurements of ribosomal translocation

Kim, Changil; Holm, Mikael; Mandava, Chandra Sekhar; Sanyal, Suparna

Part of RNA Biology, p. 2363-2375, 2021

• DOI for Optimization of a fluorescent-mRNA based real-time assay for precise kinetic measurements of ribosomal translocation
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Repurposing tRNAs for nonsense suppression

Albers, Suki; Beckert, Bertrand; Matthies, Marco C.; Mandava, Chandra Sekhar et al.

Part of Nature Communications, 2021

• DOI for Repurposing tRNAs for nonsense suppression
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Kinetic Analysis Suggests Evolution of Ribosome Snecificity in Modern Elongation Factor-Tus from "Generalist" Ancestors

De Tarafder, Arindam; Parajuli, Narayan Prasad; Majumdar, Soneya; Kacar, Betul et al.

Part of Molecular biology and evolution, p. 3436-3444, 2021

• DOI for Kinetic Analysis Suggests Evolution of Ribosome Snecificity in Modern Elongation Factor-Tus from "Generalist" Ancestors

Cotranslational recruitment of ribosomes in protocells recreates a translocon-independent mechanism of proteorhodopsin biogenesis

Eaglesfield, Ross; Madsen, Mary Ann; Sanyal, Suparna; Reboud, Julien et al.

Part of iScience, 2021

• DOI for Cotranslational recruitment of ribosomes in protocells recreates a translocon-independent mechanism of proteorhodopsin biogenesis
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GGQ methylation enhances both speed and accuracy of stop codon recognition by bacterial class-I release factors

Pundir, Shreya; Ge, Xueliang; Sanyal, Suparna

Part of Journal of Biological Chemistry, 2021

• DOI for GGQ methylation enhances both speed and accuracy of stop codon recognition by bacterial class-I release factors
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Mechanistic insights into translation inhibition by aminoglycoside antibiotic arbekacin

Parajuli, Narayan Prasad; Mandava, Chandra Sekhar; Pavlov, Michael; Sanyal, Suparna

Part of Nucleic Acids Research, p. 6880-6892, 2021

• DOI for Mechanistic insights into translation inhibition by aminoglycoside antibiotic arbekacin

Ribosomal RNA Modulates Aggregation of thePodosporaPrion Protein HET-s

Pang, Yanhong; Kovachev, Petar Stefanov; Sanyal, Suparna

Part of International Journal of Molecular Sciences, 2020

• DOI for Ribosomal RNA Modulates Aggregation of thePodosporaPrion Protein HET-s
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Loss of a single methylation in 23S rRNA delays 50S assembly at multiple late stages and impairs translation initiation and elongation

Wang, Li; Wanqiu, Li; Ge, Xueliang; Kaige, Yan et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 15609-15619, 2020

• DOI for Loss of a single methylation in 23S rRNA delays 50S assembly at multiple late stages and impairs translation initiation and elongation

Collateral toxicity limits the evolution of bacterial Release Factor 2 towards total omnipotence

Abdalaal, Hind; Pundir, Shreya; Ge, Xueliang; Sanyal, Suparna et al.

Part of Molecular biology and evolution, p. 2918-2930, 2020

• DOI for Collateral toxicity limits the evolution of bacterial Release Factor 2 towards total omnipotence
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Selective translation by alternative bacterial ribosomes

Chen, Yu-Xiang; Xu, Zhi-Yu; Ge, Xueliang; Hong, Jia-Yao et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 19487-19496, 2020

• DOI for Selective translation by alternative bacterial ribosomes
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RNA modulates aggregation of the recombinant mammalian prion protein by direct interaction

Kovachev, Petar Stefanov; Gomes, Mariana P. B.; Cordeiro, Yraima; Ferreira, Natalia C. et al.

Part of Scientific Reports, 2019

• DOI for RNA modulates aggregation of the recombinant mammalian prion protein by direct interaction
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The mechanism of error induction by the antibiotic viomycin provides insight into the fidelity mechanism of translation

Holm, Mikael; Mandava, Chandra Sekhar; Ehrenberg, Måns; Sanyal, Suparna

Part of eLIFE, 2019

• DOI for The mechanism of error induction by the antibiotic viomycin provides insight into the fidelity mechanism of translation
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Inhibition of translation termination by small molecules targeting ribosomal release factors

Ge, Xueliang; Oliveira, Ana; Hjort, Karin; Bergfors, Terese et al.

Part of Scientific Reports, 2019

• DOI for Inhibition of translation termination by small molecules targeting ribosomal release factors
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Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-Tu(H84A)

Fislage, Marcus; Zhang, Jingji; Brown, Zuben Patrick; Mandava, Chandra Sekhar et al.

Part of Nucleic Acids Research, p. 5861-5874, 2018

• DOI for Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-Tu(H84A)
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Cryo-EM structure of Mycobacterium smegmatis ribosome reveals two unidentified ribosomal proteins close to the functional centers

Li, Zhifei; Ge, Xueliang; Zhang, Yixiao; Zheng, Lvqin et al.

Part of Protein & Cell, p. 384-388, 2018

• DOI for Cryo-EM structure of Mycobacterium smegmatis ribosome reveals two unidentified ribosomal proteins close to the functional centers
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Binding Characteristics of Anticancer Drug Doxorubicin with Two-Dimensional Graphene and Graphene Oxide: Insights from Density Functional Theory Calculations and Fluorescence Spectroscopy

Vovusha, Hakkim; Banerjee, Debapriya; Yadav, Manoj Kumar; Perrozzi, Francesco et al.

Part of The Journal of Physical Chemistry C, p. 21031-21038, 2018

• DOI for Binding Characteristics of Anticancer Drug Doxorubicin with Two-Dimensional Graphene and Graphene Oxide: Insights from Density Functional Theory Calculations and Fluorescence Spectroscopy

Catalytic O- to N-Alkyl Migratory Rearrangement: Transition Metal-Free Direct and Tandem Routes to N-Alkylated Pyridones and Benzothiazolones

Mishra, Abhishek Kumar; Morgon, Nelson Henrique; Sanyal, Suparna; de Souza, Aguinaldo Robinson et al.

Part of Advanced Synthesis and Catalysis, p. 3930-3939, 2018

• DOI for Catalytic O- to N-Alkyl Migratory Rearrangement: Transition Metal-Free Direct and Tandem Routes to N-Alkylated Pyridones and Benzothiazolones

Complementary charge-based interaction between the ribosomal-stalk protein L7/12 and IF2 is the key to rapid subunit association

Ge, Xueliang; Mandava, Chandra Sekhar; Lind, Christoffer; Åqvist, Johan et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 4649-4654, 2018

• DOI for Complementary charge-based interaction between the ribosomal-stalk protein L7/12 and IF2 is the key to rapid subunit association

Experimental Evolution of Escherichia coli Harboring an Ancient Translation Protein

Kacar, Betuel; Ge, Xueliang; Sanyal, Suparna; Gaucher, Eric A.

Part of Journal of Molecular Evolution, p. 69-84, 2017

• DOI for Experimental Evolution of Escherichia coli Harboring an Ancient Translation Protein
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A genetically encoded fluorescent tRNA is active in live-cell protein synthesis

Masuda, Isao; Igarashi, Takao; Sakaguchi, Reiko; Nitharwal, Ram G. et al.

Part of Nucleic Acids Research, p. 4081-4093, 2017

• DOI for A genetically encoded fluorescent tRNA is active in live-cell protein synthesis
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New melanocortin-like peptide of E. coli can suppress inflammation via the mammalian melanocortin-1 receptor (MC1R): possible endocrine-like function for microbes of the gut.

Qiang, Xiaoling; Liotta, Anthony S; Shiloach, Joseph; Gutierrez, J C et al.

Part of npj Biofilms and Microbiomes, 2017

• DOI for New melanocortin-like peptide of E. coli can suppress inflammation via the mammalian melanocortin-1 receptor (MC1R): possible endocrine-like function for microbes of the gut.
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Regulation of PfEMP1-VAR2CSA translation by a Plasmodium translation-enhancing factor

Chan, Sherwin; Frasch, Alejandra; Mandava, Chandra Sekhar; Ch'ng, Jun-Hong et al.

Part of Nature Microbiology, 2017

• DOI for Regulation of PfEMP1-VAR2CSA translation by a Plasmodium translation-enhancing factor

Distinct modulatory role of RNA in the aggregation of the tumor suppressor protein p53 core domain.

Kovachev, Petar Stefanov; Banerjee, Debapriya; Rangel, Luciana Pereira; Eriksson, Jonny et al.

Part of Journal of Biological Chemistry, p. 9345-9357, 2017

• DOI for Distinct modulatory role of RNA in the aggregation of the tumor suppressor protein p53 core domain.

R213I mutation in release factor 2 (RF2) is one step forward for engineering an omnipotent release factor in bacteria Escherichia coli

Korkmaz, Gürkan; Sanyal, Suparna

Part of Journal of Biological Chemistry, p. 15134-15142, 2017

• DOI for R213I mutation in release factor 2 (RF2) is one step forward for engineering an omnipotent release factor in bacteria Escherichia coli

Spatial Distribution and Ribosome-Binding Dynamics of EF-P in Live Escherichia coli

Mohapatra, Sonisilpa; Choi, Heejun; Ge, Xueliang; Sanyal, Suparna et al.

Part of mBio, 2017

• DOI for Spatial Distribution and Ribosome-Binding Dynamics of EF-P in Live Escherichia coli
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Micrococcin P1-A bactericidal thiopeptide active against Mycobacterium tuberculosis

Degiacomi, Giulia; Personne, Yoann; Mondesert, Guillaume; Ge, Xueliang et al.

Part of Tuberculosis, p. 95-101, 2016

• DOI for Micrococcin P1-A bactericidal thiopeptide active against Mycobacterium tuberculosis

Molecular mechanism of viomycin inhibition of peptide elongation in bacteria

Holm, Mikael; Borg, Anneli; Ehrenberg, Måns; Sanyal, Suparna

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 978-983, 2016

• DOI for Molecular mechanism of viomycin inhibition of peptide elongation in bacteria

Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G

Li, Wen; Liu, Zheng; Koripella, Ravi Kiran; Langlois, Robert et al.

Part of Science Advances, 2015

• DOI for Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G
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A conserved histidine in switch-II of EF-G moderates release of inorganic phosphate

Koripella, Ravi Kiran; Holm, Mikael; Dourado, Daniel; Mandava, Chandra Sekhar et al.

Part of Scientific Reports, 2015

• DOI for A conserved histidine in switch-II of EF-G moderates release of inorganic phosphate
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Fusidic Acid Targets Elongation Factor G in Several Stages of Translocation on the Bacterial Ribosome

Borg, Anneli; Holm, Mikael; Shiroyama, Ikue; Hauryliuk, Vasili et al.

Part of Journal of Biological Chemistry, p. 3440-3454, 2015

• DOI for Fusidic Acid Targets Elongation Factor G in Several Stages of Translocation on the Bacterial Ribosome

Electronic structure and spectroscopic properties of 6-aminophenanthridine and its derivatives: Insights from density functional theory

Vovusha, Hakkim; Banerjee, Debapriya; Oumata, Nassima; Sanyal, Biplab et al.

Part of International Journal of Quantum Chemistry, p. 846-852, 2015

• DOI for Electronic structure and spectroscopic properties of 6-aminophenanthridine and its derivatives: Insights from density functional theory

HflX is a ribosome-splitting factor rescuing stalled ribosomes under stress conditions

Zhang, Yanqing; Mandava, Chandra Sekhar; Cao, Wei; Li, Xiaojing et al.

Part of Nature Structural & Molecular Biology, p. 906-913, 2015

• DOI for HflX is a ribosome-splitting factor rescuing stalled ribosomes under stress conditions

Characterizing an engineered release factor capable of reading all three stop codons

Korkmaz, Gürkan; Lind, Christoffer; Åqvist, Johan; Sanyal, Suparna

Part of The FASEB Journal, 2014

Structural and Functional Insights into the Mode of Action of a Universally Conserved Obg GTPase

Feng, Boya; Mandava, Chandra Sekhar; Guo, Qiang; Wang, Jie et al.

Part of PLoS biology, 2014

• DOI for Structural and Functional Insights into the Mode of Action of a Universally Conserved Obg GTPase
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Organization of Ribosomes and Nucleoids in Escherichia coli Cells during Growth and in Quiescence

Chai, Qian; Singh, Bhupender; Peisker, Kristin; Metzendorf, Nicole et al.

Part of Journal of Biological Chemistry, p. 11342-11352, 2014

• DOI for Organization of Ribosomes and Nucleoids in Escherichia coli Cells during Growth and in Quiescence

Comprehensive Analysis of Stop Codon Usage in Bacteria and Its Correlation with Release Factor Abundance

Korkmaz, Gürkan; Holm, Mikael; Wiens, Tobias; Sanyal, Suparna

Part of Journal of Biological Chemistry, p. 30334-30342, 2014

• DOI for Comprehensive Analysis of Stop Codon Usage in Bacteria and Its Correlation with Release Factor Abundance

Structure-Activity Relationship Study around Guanabenz Identifies Two Derivatives Retaining Antiprion Activity but Having Lost alpha 2-Adrenergic Receptor Agonistic Activity

Nguyen, Phu Hai; Hammoud, Hassan; Halliez, Sophie; Pang, Yanhong et al.

Part of ACS Chemical Neuroscience, p. 1075-1082, 2014

• DOI for Structure-Activity Relationship Study around Guanabenz Identifies Two Derivatives Retaining Antiprion Activity but Having Lost alpha 2-Adrenergic Receptor Agonistic Activity

Spectroscopic and DFT studies on 6-Aminophenanthridine and its derivatives provide insights in their activity towards ribosomal RNA

Banerjee, Debapriya; Vovusha, Hakkim; Pang, Yanhong; Oumata, Nassima et al.

Part of Biochimie, p. 194-199, 2014

• DOI for Spectroscopic and DFT studies on 6-Aminophenanthridine and its derivatives provide insights in their activity towards ribosomal RNA

Interaction of Nucleobases and Aromatic Amino Acids with Graphene Oxide and Graphene Flakes

Vovusha, Hakkim; Sanyal, Suparna; Sanyal, Biplab

Part of The Journal of Physical Chemistry Letters, p. 3710-3718, 2013

• DOI for Interaction of Nucleobases and Aromatic Amino Acids with Graphene Oxide and Graphene Flakes

The Toll-Like Receptor Agonist Imiquimod Is Active against Prions

Oumata, Nassima; Nguyen, Phu Hai; Beringue, Vincent; Soubigou, Flavie et al.

Part of PLOS ONE, 2013

• DOI for The Toll-Like Receptor Agonist Imiquimod Is Active against Prions
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The Antiprion Compound 6-Aminophenanthridine Inhibits the Protein Folding Activity of the Ribosome by Direct Competition

Pang, Yanhong; Kurella, Sriram; Voisset, Cecile; Samanta, Dibyendu et al.

Part of Journal of Biological Chemistry, p. 19081-19089, 2013

• DOI for The Antiprion Compound 6-Aminophenanthridine Inhibits the Protein Folding Activity of the Ribosome by Direct Competition

Cryo-EM visualization of the ribosome in termination complex with apo-RF3 and RF1

Pallesen, Jesper; Hashem, Yaser; Korkmaz, Gürkan; Koripella, Ravi Kiran et al.

Part of eLife, 2013

• DOI for Cryo-EM visualization of the ribosome in termination complex with apo-RF3 and RF1
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Bacterial ribosome requires multiple L12 dimers for efficient initiation and elongation of protein synthesis involving IF2 and EF-G

Mandava, Chandra Sekhar; Peisker, Kristin; Ederth, Josefine; Kumar, Ranjeet et al.

Part of Nucleic Acids Research, p. 2054-2064, 2012

• DOI for Bacterial ribosome requires multiple L12 dimers for efficient initiation and elongation of protein synthesis involving IF2 and EF-G
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Structure and function of FusB: an elongation factor G-binding fusidic acid resistance protein active in ribosomal translocation and recycling

Guo, Xiaohu; Peisker, Kristin; Bäckbro, Kristina; Chen, Yang et al.

Part of Open Biology, p. 120016, 2012

• DOI for Structure and function of FusB: an elongation factor G-binding fusidic acid resistance protein active in ribosomal translocation and recycling

Mechanism of Elongation Factor-G-mediated Fusidic Acid Resistance and Fitness Compensation in Staphylococcus aureus

Koripella, Ravi Kiran; Chen, Yang; Peisker, Kristin; Koh, Cha San et al.

Part of Journal of Biological Chemistry, p. 30257-30267, 2012

• DOI for Mechanism of Elongation Factor-G-mediated Fusidic Acid Resistance and Fitness Compensation in Staphylococcus aureus

Mechanism and Rates of Exchange of L7/L12 between Ribosomes and the Effects of Binding EF-G

Deroo, Stephanie; Hyung, Suk-Joon; Marcoux, Julien; Gordiyenko, Yuliya et al.

Part of ACS Chemical Biology, p. 1120-1127, 2012

• DOI for Mechanism and Rates of Exchange of L7/L12 between Ribosomes and the Effects of Binding EF-G

Mode of action of the antiprion drugs 6AP and GA on ribosome assisted protein folding

Dos Reis, Suzana; Pang, Yanhong; Vishnu, Neelanjan; Voisset, Cécile et al.

Part of Biochimie, p. 1047-1054, 2011

• DOI for Mode of action of the antiprion drugs 6AP and GA on ribosome assisted protein folding

Ribosomes lacking protein S20 are defective in mRNA binding and subunit association

Tobin, Christina; Mandava, Chandra Sekhar; Ehrenberg, Måns; Andersson, Dan I et al.

Part of Journal of Molecular Biology, p. 767-776, 2010

• DOI for Ribosomes lacking protein S20 are defective in mRNA binding and subunit association

Staphylococcus aureus elongation factor G - structure and analysis of a target for fusidic acid

Chen, Yang; Koripella, Ravi Kiran; Sanyal, Suparna; Selmer, Maria

Part of The FEBS Journal, p. 3789-3803, 2010

• DOI for Staphylococcus aureus elongation factor G - structure and analysis of a target for fusidic acid

The Ribosomal Stalk Plays a Key Role in IF2-Mediated Association of the Ribosomal Subunits

Huang, Chenhui; Mandava, Chandra Sekhar; Sanyal, Suparna

Part of Journal of Molecular Biology, p. 145-153, 2010

• DOI for The Ribosomal Stalk Plays a Key Role in IF2-Mediated Association of the Ribosomal Subunits

A single-step method for purification of active His-tagged ribosomes from a genetically engineered Escherichia coli

Ederth, Josefine; Mandava, Chandra Sekhar; Dasgupta, Santanu; Sanyal, Suparna

Part of Nucleic Acids Research, 2009

• DOI for A single-step method for purification of active His-tagged ribosomes from a genetically engineered Escherichia coli

Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM

Li, Wen; Agirrezabala, Xabier; Lei, Jianlin; Bouakaz, Lamine et al.

Part of EMBO Journal, p. 3322-3331, 2008

• DOI for Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM

Protein Folding Activity of Ribosomal RNA Is a Selective Target of Two Unrelated Antiprion Drugs

Tribouillard-Tanvier, Deborah; Dos Reis, Suzana; Gug, Fabienne; Voisset, Cecile et al.

Part of PloS one, 2008

• DOI for Protein Folding Activity of Ribosomal RNA Is a Selective Target of Two Unrelated Antiprion Drugs

The ribosomal stalk binds to translation factors IF2, EF-Tu, EF-G and RF3 via a conserved region of the L12 C-terminal domain

Helgstrand, Magnus; Mandava, Chandra S.; Mulder, Frans A. A.; Liljas, Anders et al.

Part of Journal of Molecular Biology, p. 468-479, 2007

• DOI for The ribosomal stalk binds to translation factors IF2, EF-Tu, EF-G and RF3 via a conserved region of the L12 C-terminal domain

RF3 induces ribosomal conformational changes responsible for dissociation of class I release factors

Gao, Haixiao; Zhou, Zhihong; Rawat, Urmila; Huang, Chenhui et al.

Part of Cell, p. 929-941, 2007

• DOI for RF3 induces ribosomal conformational changes responsible for dissociation of class I release factors

Immobilized β-cyclodextrin polymer coupled to agarose gel properly refolding recombinant Staphylococcus aureus elongation factor-G in combination with detergent micelle

Li, Jing-Jing; Venkataramana, Musturi; Sanyal, Suparna; Janson, Jan-Christer et al.

Part of Protein Expression and Purification, p. 72-79, 2006

Synthesis and biological evaluation of photoaffinity labeled fusidic acid analogues.

Riber, Ditte; Venkataramana, Musturi; Sanyal, Suparna; Duvold, Tore

Part of J Med Chem, p. 1503-5, 2006

A mild hydrophobic interaction chromatography involving polyethylene glycol immobilized to agarose media refolding recombinant Staphylococcus aureus elongation factor G

Li, Jing-Jing; Venkataramana; Wang, Ai-Qing; Sanyal, Suparna et al.

Part of Protein Expression and Purification, p. 327-335, 2005

Over expression of a tRNA(Leu) isoacceptor changes charging pattern of leucine tRNAs and reveals new codon reading.

Sörensen, Michael A; Elf, Johan; Bouakaz, Elli; Tenson, Tanel et al.

Part of J Mol Biol, p. 16-24, 2005

The SAXS solution structure of RF1 differs from its crystal structure and is similar to its ribosome bound cryo-EM structure.

Vestergaard, Bente; Sanyal, Suparna; Roessle, Manfred; Mora, Liliana et al.

Part of Mol Cell, p. 929-38, 2005

p53 Isoforms as Cancer Biomarkers and Therapeutic Targets

Zhao, Liuqun; Sanyal, Suparna

Part of Cancers, 2022

• DOI for p53 Isoforms as Cancer Biomarkers and Therapeutic Targets
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Modulation of p53 and prion protein aggregation by RNA

Cordeiro, Yraima; Vieira, Tuane; Kovachev, Petar Stefanov; Sanyal, Suparna et al.

Part of Biochimica et Biophysica Acta - Proteins and Proteomics, p. 933-940, 2019

• DOI for Modulation of p53 and prion protein aggregation by RNA

The enigmatic ribosomal stalk

Liljas, Anders; Sanyal, Suparna

Part of Quarterly reviews of biophysics (Print), 2018

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p53 Isoforms and Their Implications in Cancer

Vieler, Maximilian; Sanyal, Suparna

Part of Cancers, 2018

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p53 Isoforms and Their Implications in Cancer

Vieler, Maximilian; Sanyal, Suparna

Part of Cancers, 2018

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Protein Folding Activity of the Ribosome (PFAR): A Target for Antiprion Compounds

Banerjee, Debapriya; Sanyal, Suparna

Part of Viruses, p. 3907-3924, 2014

• DOI for Protein Folding Activity of the Ribosome (PFAR): A Target for Antiprion Compounds
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Initiation of bacterial protein synthesis with wild type and novel mutants of initiation factor

Pavlov, Michael Y.; Sanyal, Suparna; Ehrenberg, Måns

Part of Ribosomes, p. 129-141, 2011

Distribution of ribosomes in action and at rest in Escherichia coli: involvement of bacterial cytoskeleton

Chai, Qian; Singh, Bhupender; Peisker, Kristin; Dasgupta, Santanu et al.

Essential role of Histidine 92 in elongation factor-G in GTP hydrolysis and inorganic phosphate release during elongation of protein synthesis

Koripella, Ravi Kiran; Holm, Mikael; Sanyal, Suparna

Real-time measurements of aminoglycoside effects on protein synthesis in live cells

Aguirre Rivera, Javier; Larsson, Jimmy; Seefeldt, A. Carolin; Sanyal, Suparna et al.

An extended C-terminal tail of the ribosomal protein S13 modulates the speed of ribosomal translocation.

Kim, Chang-il; Koripella, Ravi Kiran; Aguirre Rivera, Javier; Ge, Xueliang et al.

The compensatory mechanism of a naturally-evolved E167K RF2 counteracting the loss of RF1 in bacteria

Pundir, Shreya; Larsson, Daniel; Selmer, Maria; Sanyal, Suparna

The end of the beginning: structural studies of ribosomal proteins

Chandra Sanyal, S; Liljas, A

Part of Curr Opin Struct Biol, p. 633-636, 2000