Alexandros Kostakis

Optimizing T cell responses of targeted peptide antigen delivery by modulating antigen processing through amino acid exchange

Laurén, Ida; Kostakis, Alexandros; Lord, Martin; Björklund, Elvira et al.

Part of International Journal of Biological Macromolecules, 2026

• DOI for Optimizing T cell responses of targeted peptide antigen delivery by modulating antigen processing through amino acid exchange
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A bispecific CD40 agonistic antibody allowing for antibody-peptide conjugate formation to enable cancer-specific peptide delivery, resulting in improved T proliferation and anti-tumor immunity in mice

Mebrahtu, Aman; Laurén, Ida; Veerman, Rosanne; Güclüler Akpinar, Gözde et al.

Part of Nature Communications, 2024

• DOI for A bispecific CD40 agonistic antibody allowing for antibody-peptide conjugate formation to enable cancer-specific peptide delivery, resulting in improved T proliferation and anti-tumor immunity in mice
• Download full text (pdf) of A bispecific CD40 agonistic antibody allowing for antibody-peptide conjugate formation to enable cancer-specific peptide delivery, resulting in improved T proliferation and anti-tumor immunity in mice

Elevated levels of MMP12 sourced from macrophages are associated with poor prognosis in urothelial bladder cancer

Kerzeli, Iliana Kyriaki; Kostakis, Alexandros; Türker, Polat; Malmström, Per-Uno et al.

Part of BMC Cancer, 2023

• DOI for Elevated levels of MMP12 sourced from macrophages are associated with poor prognosis in urothelial bladder cancer
• Download full text (pdf) of Elevated levels of MMP12 sourced from macrophages are associated with poor prognosis in urothelial bladder cancer

The tumour microenvironment across tumour evolution in bladder cancer profiled by single-cell RNA-sequencing analysis and spatial transcriptomics

Kostakis, Alexandros; Beháňová, Andrea; Kyriaki Kerzeli, Iliana; Elgendy, Ramy et al.

Optimizing T cell responses of targeted peptide antigen delivery by modulating antigen processing through amino acid exchange

Laurén, Ida; Kostakis, Alexandros; Lord, Martin; Björklund, Elvira et al.

Part of International Journal of Biological Macromolecules, 2026

• DOI for Optimizing T cell responses of targeted peptide antigen delivery by modulating antigen processing through amino acid exchange
• Download full text (pdf) of Optimizing T cell responses of targeted peptide antigen delivery by modulating antigen processing through amino acid exchange

A bispecific CD40 agonistic antibody allowing for antibody-peptide conjugate formation to enable cancer-specific peptide delivery, resulting in improved T proliferation and anti-tumor immunity in mice

Mebrahtu, Aman; Laurén, Ida; Veerman, Rosanne; Güclüler Akpinar, Gözde et al.

Part of Nature Communications, 2024

• DOI for A bispecific CD40 agonistic antibody allowing for antibody-peptide conjugate formation to enable cancer-specific peptide delivery, resulting in improved T proliferation and anti-tumor immunity in mice
• Download full text (pdf) of A bispecific CD40 agonistic antibody allowing for antibody-peptide conjugate formation to enable cancer-specific peptide delivery, resulting in improved T proliferation and anti-tumor immunity in mice

Elevated levels of MMP12 sourced from macrophages are associated with poor prognosis in urothelial bladder cancer

Kerzeli, Iliana Kyriaki; Kostakis, Alexandros; Türker, Polat; Malmström, Per-Uno et al.

Part of BMC Cancer, 2023

• DOI for Elevated levels of MMP12 sourced from macrophages are associated with poor prognosis in urothelial bladder cancer
• Download full text (pdf) of Elevated levels of MMP12 sourced from macrophages are associated with poor prognosis in urothelial bladder cancer

The tumour microenvironment across tumour evolution in bladder cancer profiled by single-cell RNA-sequencing analysis and spatial transcriptomics

Kostakis, Alexandros; Beháňová, Andrea; Kyriaki Kerzeli, Iliana; Elgendy, Ramy et al.