Wojciech Piotr Michno

Brain interstitial fluid pharmacokinetics and therapeutic effect of a BBB penetrating amyloid beta antibody measured by microdialysis

Wik, Elin; Dahlén, Amelia; Julku, Ulrika; Xiong, Mengfei et al.

Part of Neurotherapeutics, 2026

• DOI for Brain interstitial fluid pharmacokinetics and therapeutic effect of a BBB penetrating amyloid beta antibody measured by microdialysis
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Exposure to fibrillar proteins leads to widespread infiltration but only mild tau pathology in cortical organoids

Dakhel, Abdulkhalek; Mothes, Tobias; Eltom, Khalid; Michno, Wojciech et al.

Part of iScience, 2026

• DOI for Exposure to fibrillar proteins leads to widespread infiltration but only mild tau pathology in cortical organoids
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MALDI mass spectrometry imaging (MSI) reveals molecular and structural heterogeneity of amyloid-β in sporadic Alzheimer's disease and Down syndrome

Minta, Karolina; Söderberg, Linda; Gkanatsiou, Eleni; Johannesson, Malin et al.

Part of Acta neuropathologica communications, 2026

• DOI for MALDI mass spectrometry imaging (MSI) reveals molecular and structural heterogeneity of amyloid-β in sporadic Alzheimer's disease and Down syndrome
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Zombosomes are anucleated cell couriers that spread α-synuclein pathology

Dakhel, Abdulkhalek; Beretta, Chiara; Mothes, Tobias; Hakhverdyan, Sona et al.

Part of Cell Reports, 2026

• DOI for Zombosomes are anucleated cell couriers that spread α-synuclein pathology
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High-throughput oxygen consumption measurements in self-organizing 3D models under tuneable chemical environments

Tenje, Maria; Cui, Yuan; Hakhverdyan, Sona; Luk, Nicole Sui Man et al.

2025

Brain interstitial fluid pharmacokinetics and therapeutic effect of a BBB penetrating amyloid beta antibody measured by microdialysis

Wik, Elin; Dahlén, Amelia; Julku, Ulrika; Xiong, Mengfei et al.

Part of Neurotherapeutics, 2026

• DOI for Brain interstitial fluid pharmacokinetics and therapeutic effect of a BBB penetrating amyloid beta antibody measured by microdialysis
• Download full text (pdf) of Brain interstitial fluid pharmacokinetics and therapeutic effect of a BBB penetrating amyloid beta antibody measured by microdialysis

Exposure to fibrillar proteins leads to widespread infiltration but only mild tau pathology in cortical organoids

Dakhel, Abdulkhalek; Mothes, Tobias; Eltom, Khalid; Michno, Wojciech et al.

Part of iScience, 2026

• DOI for Exposure to fibrillar proteins leads to widespread infiltration but only mild tau pathology in cortical organoids
• Download full text (pdf) of Exposure to fibrillar proteins leads to widespread infiltration but only mild tau pathology in cortical organoids

MALDI mass spectrometry imaging (MSI) reveals molecular and structural heterogeneity of amyloid-β in sporadic Alzheimer's disease and Down syndrome

Minta, Karolina; Söderberg, Linda; Gkanatsiou, Eleni; Johannesson, Malin et al.

Part of Acta neuropathologica communications, 2026

• DOI for MALDI mass spectrometry imaging (MSI) reveals molecular and structural heterogeneity of amyloid-β in sporadic Alzheimer's disease and Down syndrome
• Download full text (pdf) of MALDI mass spectrometry imaging (MSI) reveals molecular and structural heterogeneity of amyloid-β in sporadic Alzheimer's disease and Down syndrome

Zombosomes are anucleated cell couriers that spread α-synuclein pathology

Dakhel, Abdulkhalek; Beretta, Chiara; Mothes, Tobias; Hakhverdyan, Sona et al.

Part of Cell Reports, 2026

• DOI for Zombosomes are anucleated cell couriers that spread α-synuclein pathology
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Bispecific brain-penetrant antibodies for treatment of Alzheimer's disease

Sehlin, Dag; Hultqvist, Greta; Michno, Wojciech; Aguilar, Ximena et al.

Part of The Journal of Prevention of Alzheimer's Disease, 2025

• DOI for Bispecific brain-penetrant antibodies for treatment of Alzheimer's disease
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Astrocytic lipid droplets contain MHCII and may act as cogs in the antigen presentation machinery

Beretta, Chiara; Dakhel, Abdulkhalek; Eltom, Khalid; Rosqvist, Fredrik et al.

Part of Journal of Neuroinflammation, 2025

• DOI for Astrocytic lipid droplets contain MHCII and may act as cogs in the antigen presentation machinery
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Chemical imaging delineates Aβ plaque polymorphism across the Alzheimer’s disease spectrum

Koutarapu, Srinivas; Ge, Junyue; Dulewicz, Maciej; Srikrishna, Meera et al.

Part of Nature Communications, 2025

• DOI for Chemical imaging delineates Aβ plaque polymorphism across the Alzheimer’s disease spectrum
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Spatial Neurolipidomics at the Single Amyloid-β Plaque Level in Postmortem Human Alzheimer's Disease Brain

Michno, Wojciech; Bowman, Andrew; Jha, Durga; Minta, Karolina et al.

Part of ACS Chemical Neuroscience, p. 877-888, 2024

• DOI for Spatial Neurolipidomics at the Single Amyloid-β Plaque Level in Postmortem Human Alzheimer's Disease Brain
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Amyloid-β deposits in human astrocytes contain truncated and highly resistant proteoforms

Beretta, Chiara; Svensson, Elina; Dakhel, Abdulkhalek; Zyśk, Marlena et al.

Part of Molecular and Cellular Neuroscience, 2024

• DOI for Amyloid-β deposits in human astrocytes contain truncated and highly resistant proteoforms
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High-throughput oxygen consumption measurements in self-organizing 3D models under tuneable chemical environments

Tenje, Maria; Cui, Yuan; Hakhverdyan, Sona; Luk, Nicole Sui Man et al.

2025

Astrocytes with Alzheimer’s disease pathology provoke lipid droplet mediated cell-to-cell propagation of MHC II complexes

Beretta, Chiara; Dakhel, Abdulkhalek; Eltom, Khalid; Rosqvist, Fredrik et al.