Jakob Haglöf
Lecturer at Department of Medicinal Chemistry; Analytical Pharmaceutical Chemistry
- Telephone:
- +46 18 471 43 41
- E-mail:
- jakob.haglof@ilk.uu.se
- Visiting address:
- Uppsala biomedicinska centrum BMC, Husarg. 3
- Postal address:
- Box 574
751 23 UPPSALA
Short presentation
With a background as engineer in Biotechnology and a PhD in Pharmacy I work as a lecturer and researcher in analytical pharmaceutical chemistry. As lecturer I teach students within the pharmacist, engineering and dispensing pharmacist programmes in pharmaceutical analysis. My research is aimed at developing separation methods for oligonucleotide (miRNA, siRNA) analysis, as well as analytical methods for metabolomics studies, with a particular focus on high data quality.
Keywords
- analytical chemistry
- capillary electrophoresis
- chromatography
- mass spectrometry
- metabolomics
- chemometrics
- pharmaceutical analysis
- bioanalysis
- experimental design
- oligonucleotides
Biography
2004: MSc in Biotechnology, Chalmers University of Technology
2010: PhD in Pharmacy, Uppsala universitet
2021: Distinguished teacher, Uppsala University

Publications
Recent publications
-
Part of Analytica Chimica Acta, 2026
- DOI for Systematic optimization of gel-free capillary zone electrophoresis for phosphodiester oligonucleotide separations at acidic pH
- Download full text (pdf) of Systematic optimization of gel-free capillary zone electrophoresis for phosphodiester oligonucleotide separations at acidic pH
-
Part of Journal of Separation Science, 2025
- DOI for Development of Enhanced Separation Techniques for Oligonucleotides Utilizing Mixed-Mode Chromatography and 2D-LC/UV/MS Analysis
- Download full text (pdf) of Development of Enhanced Separation Techniques for Oligonucleotides Utilizing Mixed-Mode Chromatography and 2D-LC/UV/MS Analysis
-
Gel-free capillary zone electrophoresis at acidic pH for micro DNA and RNA analysis
Part of Talanta, 2025
- DOI for Gel-free capillary zone electrophoresis at acidic pH for micro DNA and RNA analysis
- Download full text (pdf) of Gel-free capillary zone electrophoresis at acidic pH for micro DNA and RNA analysis
-
DNA integrity under alkaline conditions: An investigation of factors affecting the comet assay
Part of Mutation research. Genetic toxicology and environmental mutagenesis, 2023
- DOI for DNA integrity under alkaline conditions: An investigation of factors affecting the comet assay
- Download full text (pdf) of DNA integrity under alkaline conditions: An investigation of factors affecting the comet assay
-
Oceanographic setting influences the prokaryotic community and metabolome in deep-sea sponges
Part of Scientific Reports, 2022
- DOI for Oceanographic setting influences the prokaryotic community and metabolome in deep-sea sponges
- Download full text (pdf) of Oceanographic setting influences the prokaryotic community and metabolome in deep-sea sponges
All publications
Articles in journal
-
Part of Analytica Chimica Acta, 2026
- DOI for Systematic optimization of gel-free capillary zone electrophoresis for phosphodiester oligonucleotide separations at acidic pH
- Download full text (pdf) of Systematic optimization of gel-free capillary zone electrophoresis for phosphodiester oligonucleotide separations at acidic pH
-
Part of Journal of Separation Science, 2025
- DOI for Development of Enhanced Separation Techniques for Oligonucleotides Utilizing Mixed-Mode Chromatography and 2D-LC/UV/MS Analysis
- Download full text (pdf) of Development of Enhanced Separation Techniques for Oligonucleotides Utilizing Mixed-Mode Chromatography and 2D-LC/UV/MS Analysis
-
Gel-free capillary zone electrophoresis at acidic pH for micro DNA and RNA analysis
Part of Talanta, 2025
- DOI for Gel-free capillary zone electrophoresis at acidic pH for micro DNA and RNA analysis
- Download full text (pdf) of Gel-free capillary zone electrophoresis at acidic pH for micro DNA and RNA analysis
-
DNA integrity under alkaline conditions: An investigation of factors affecting the comet assay
Part of Mutation research. Genetic toxicology and environmental mutagenesis, 2023
- DOI for DNA integrity under alkaline conditions: An investigation of factors affecting the comet assay
- Download full text (pdf) of DNA integrity under alkaline conditions: An investigation of factors affecting the comet assay
-
Oceanographic setting influences the prokaryotic community and metabolome in deep-sea sponges
Part of Scientific Reports, 2022
- DOI for Oceanographic setting influences the prokaryotic community and metabolome in deep-sea sponges
- Download full text (pdf) of Oceanographic setting influences the prokaryotic community and metabolome in deep-sea sponges
-
A distinct metabolic response characterizes sensitivity to EZH2 inhibition in multiple myeloma
Part of Cell Death and Disease, 2021
- DOI for A distinct metabolic response characterizes sensitivity to EZH2 inhibition in multiple myeloma
- Download full text (pdf) of A distinct metabolic response characterizes sensitivity to EZH2 inhibition in multiple myeloma
-
Part of Frontiers in Oncology, 2019
- DOI for Exploring Radiation Response in Two Head and Neck Squamous Carcinoma Cell Lines Through Metabolic Profiling
- Download full text (pdf) of Exploring Radiation Response in Two Head and Neck Squamous Carcinoma Cell Lines Through Metabolic Profiling
-
Part of Metabolomics, 2019
- DOI for An LCMS-based untargeted metabolomics protocol for cochlear perilymph: highlighting metabolic effects of hydrogen gas on the inner ear of noise exposed Guinea pigs
- Download full text (pdf) of An LCMS-based untargeted metabolomics protocol for cochlear perilymph: highlighting metabolic effects of hydrogen gas on the inner ear of noise exposed Guinea pigs
-
Part of Journal of Chromatography A, p. 174-182, 2019
-
Part of Journal of Chromatography A, p. 49-56, 2018
-
Part of International Journal of Oncology, p. 5-14, 2017
- DOI for Different functions of AKT1 and AKT2 in molecular pathways, cell migration and metabolism in colon cancer cells
- Download full text (pdf) of Different functions of AKT1 and AKT2 in molecular pathways, cell migration and metabolism in colon cancer cells
-
Part of Amino Acids, p. 905-919, 2017
- DOI for β-N-Methylamino-L-alanine (BMAA) perturbs alanine, aspartate and glutamate metabolism pathways in human neuroblastoma cells as determined by metabolic profiling
- Download full text (pdf) of β-N-Methylamino-L-alanine (BMAA) perturbs alanine, aspartate and glutamate metabolism pathways in human neuroblastoma cells as determined by metabolic profiling
-
Part of Acta Oto-Laryngologica, p. 1024-1030, 2017
-
Part of Analytica Chimica Acta, p. 40-47, 2017
-
TAp73 is a marker of glutamine addiction in medulloblastoma
Part of Genes & Development, p. 1738-1753, 2017
- DOI for TAp73 is a marker of glutamine addiction in medulloblastoma
- Download full text (pdf) of TAp73 is a marker of glutamine addiction in medulloblastoma
-
Part of Nutrition & Diabetes, 2015
- DOI for NMR-based metabolic profiling in healthy individuals overfed different types of fat: links to changes in liver fat accumulation and lean tissue mass.
- Download full text (pdf) of NMR-based metabolic profiling in healthy individuals overfed different types of fat: links to changes in liver fat accumulation and lean tissue mass.
-
Part of International Journal of Pharmaceutics, p. 205-217, 2015
-
Part of Bioanalysis, p. 157-166, 2015
-
Part of Journal of chemical information and modeling, p. 3251-3258, 2014
-
Part of Amino Acids, p. 905-919, 2013
-
Separation of amino alcohols using divalent dipeptides as counter ions in aqueous CE
Part of Electrophoresis, p. 1706-1712, 2010
-
Part of Electrophoresis, p. 4469-4479, 2006