Johanna Dahlqvist
Adjunct senior lecturer at Department of Medical Sciences; Rheumatology
- Mobile phone:
- +46 70 261 68 88
- E-mail:
- johanna.dahlqvist@uu.se
- Visiting address:
- Akademiska sjukhuset, ingång 40, 5 tr
751 85 UPPSALA - Postal address:
- Akademiska sjukhuset, ingång 40, 5 tr
751 85 UPPSALA
Download contact information for Johanna Dahlqvist at Department of Medical Sciences; Rheumatology
- Academic merits:
- Associate professor
Short presentation
As a physician scientist, I combine patient-centered work at the Unit of Rheumatology, Uppsala University Hospital, with basic and clinical research. The scope of my research comprises investigation of the basic mechanisms behind autoimmunity, with a special focus on the rare disorders ANCA-associated vasculitides, as well as clinical implications of these diseases in terms of organ damage, co-morbidities and diagnostic tools.
Research
My current research delves into the pathological mechanisms behind autoimmunity, with a special focus on the ANCA-associated vasculitides (AAV). Although rare, the AAV are severe autoimmune diseases with a potentially fatal outcome. To improve treatment and diagnostics of patients, we need to close the gap in our understanding of the cellular and molecular events leading up to disease.
In 2014, I initiated and organized a Scandinavian scientific network for a collaborative effort to improve our comprehension of the AAV (SCAVAS). We are now finalizing the first initiative, a large genetics study comprising more than 1100 patients with AAV, recruited at 10 different centra in Sweden, Norway and Denmark. The collaboration has sparked novel projects, e.g., I am now, together with co-workers, leading studies involving proteomics, single-cell transcriptomics and clinical aspects of AAV.
Previous research experience:
2011 Doctoral degree in clinical genetics, Dep. of Immunology, Genetics and Pathology, Uppsala University, Sweden.
2014 Start of post-doctoral studies in the lab of prof. Kerstin Lindblad-Toh, Dep. of Medical Biochemistry and Microbiology, Uppsala University. Area of interest: genetics of autoimmune complex traits.
2016-2018 Post-doctoral studies in the lab of prof. Nir Hacohen, the Broad Institute of MIT and Harvard, Cambridge, MA, US. Area of interest: genetic regulation of autoimmunity-associated genes.
2019- Young PI in the lab's of prof. Kerstin Lindblad-Toh and prof. Lars Rönnblom, Dep. of Medical Sciences, Uppsala University. Areas of interest: genetic predisposition to and molecular mechanisms involved in autoimmune disease; etio-pathogenesis and disease course of AAV, with the aim to deconstruct the heterogeneity among patients and improve prognosis.

Publications
Recent publications
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Part of Frontiers in Immunology, 2025
- DOI for The plasma proteome reveals distinct signaling pathways associated with PR3-ANCA positive and MPO-ANCA positive vasculitis
- Download full text (pdf) of The plasma proteome reveals distinct signaling pathways associated with PR3-ANCA positive and MPO-ANCA positive vasculitis
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Part of ACR Open Rheumatology, 2025
- DOI for In-Depth Analysis of Disease Manifestations in Antineutrophil Cytoplasmic Antibody-Associated Vasculitides Identifies Distinct Clinical Phenotypes
- Download full text (pdf) of In-Depth Analysis of Disease Manifestations in Antineutrophil Cytoplasmic Antibody-Associated Vasculitides Identifies Distinct Clinical Phenotypes
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Part of RMD Open, 2024
- DOI for The HLA region in ANCA-associated vasculitis: characterisation of genetic associations in a Scandinavian patient population
- Download full text (pdf) of The HLA region in ANCA-associated vasculitis: characterisation of genetic associations in a Scandinavian patient population
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Stratified genetic analysis reveals sex differences in MPO-ANCA-associated vasculitis
Part of Rheumatology, p. 3213-3218, 2023
- DOI for Stratified genetic analysis reveals sex differences in MPO-ANCA-associated vasculitis
- Download full text (pdf) of Stratified genetic analysis reveals sex differences in MPO-ANCA-associated vasculitis
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Part of Rheumatology, p. 3461-3470, 2022
- DOI for Identification and Functional Characterization of a Novel Susceptibility Locus for Small Vessel Vasculitis with MPO-ANCA
- Download full text (pdf) of Identification and Functional Characterization of a Novel Susceptibility Locus for Small Vessel Vasculitis with MPO-ANCA
All publications
Articles in journal
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Part of Frontiers in Immunology, 2025
- DOI for The plasma proteome reveals distinct signaling pathways associated with PR3-ANCA positive and MPO-ANCA positive vasculitis
- Download full text (pdf) of The plasma proteome reveals distinct signaling pathways associated with PR3-ANCA positive and MPO-ANCA positive vasculitis
-
Part of ACR Open Rheumatology, 2025
- DOI for In-Depth Analysis of Disease Manifestations in Antineutrophil Cytoplasmic Antibody-Associated Vasculitides Identifies Distinct Clinical Phenotypes
- Download full text (pdf) of In-Depth Analysis of Disease Manifestations in Antineutrophil Cytoplasmic Antibody-Associated Vasculitides Identifies Distinct Clinical Phenotypes
-
Part of RMD Open, 2024
- DOI for The HLA region in ANCA-associated vasculitis: characterisation of genetic associations in a Scandinavian patient population
- Download full text (pdf) of The HLA region in ANCA-associated vasculitis: characterisation of genetic associations in a Scandinavian patient population
-
Stratified genetic analysis reveals sex differences in MPO-ANCA-associated vasculitis
Part of Rheumatology, p. 3213-3218, 2023
- DOI for Stratified genetic analysis reveals sex differences in MPO-ANCA-associated vasculitis
- Download full text (pdf) of Stratified genetic analysis reveals sex differences in MPO-ANCA-associated vasculitis
-
Part of Rheumatology, p. 3461-3470, 2022
- DOI for Identification and Functional Characterization of a Novel Susceptibility Locus for Small Vessel Vasculitis with MPO-ANCA
- Download full text (pdf) of Identification and Functional Characterization of a Novel Susceptibility Locus for Small Vessel Vasculitis with MPO-ANCA
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Part of Scandinavian Journal of Rheumatology, p. 214-219, 2022
- DOI for Complement activation prior to symptom onset in myeloperoxidase ANCA-associated vasculitis but not proteinase 3 ANCA associated vasculitis-A Swedish biobank study
- Download full text (pdf) of Complement activation prior to symptom onset in myeloperoxidase ANCA-associated vasculitis but not proteinase 3 ANCA associated vasculitis-A Swedish biobank study
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Oral Microbiota Profile in Patients with Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Part of Microorganisms, 2022
- DOI for Oral Microbiota Profile in Patients with Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
- Download full text (pdf) of Oral Microbiota Profile in Patients with Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
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Part of Human Molecular Genetics, p. 1946-1961, 2021
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Part of Journal of Autoimmunity, 2021
- DOI for Anti-neutrophil cytoplasmic antibodies predate symptom onset of ANCA-associated vasculitis: A case-control study
- Download full text (pdf) of Anti-neutrophil cytoplasmic antibodies predate symptom onset of ANCA-associated vasculitis: A case-control study
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Part of Journal of Rheumatology, p. 894-897, 2021
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Part of Rheumatology, p. 943-952, 2021
- DOI for Pulmonary fibrosis in relation to genetic loci in an inception cohort of patients with early rheumatoid arthritis from northern Sweden
- Download full text (pdf) of Pulmonary fibrosis in relation to genetic loci in an inception cohort of patients with early rheumatoid arthritis from northern Sweden
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Part of Rheumatology, p. 918-919, 2019
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Part of European Journal of Human Genetics, p. 432-441, 2019
- DOI for A rare regulatory variant in the MEF2D gene affects gene regulation and splicing and is associated with a SLE sub-phenotype in Swedish cohorts
- Download full text (pdf) of A rare regulatory variant in the MEF2D gene affects gene regulation and splicing and is associated with a SLE sub-phenotype in Swedish cohorts
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Part of Annals of the Rheumatic Diseases, p. 1063-1069, 2018
- DOI for Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis
- Download full text (pdf) of Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis
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Extended exome sequencing identifies BACH2 as a novel major risk locus for Addison's disease
Part of Journal of Internal Medicine, p. 595-608, 2016
- DOI for Extended exome sequencing identifies BACH2 as a novel major risk locus for Addison's disease
- Download full text (pdf) of Extended exome sequencing identifies BACH2 as a novel major risk locus for Addison's disease