Oskar Skog

A decisive bridge between innate immunity and the pathognomonic morphological characteristics of type 1 diabetes demonstrated by instillation of heat-inactivated bacteria in the pancreatic duct of rats

Tegehall, Angie; Ingvast, Sofie; Melhus, Åsa; Skog, Oskar et al.

Part of Acta Diabetologica, p. 1011-1018, 2022

• DOI for A decisive bridge between innate immunity and the pathognomonic morphological characteristics of type 1 diabetes demonstrated by instillation of heat-inactivated bacteria in the pancreatic duct of rats
• Download full text (pdf) of A decisive bridge between innate immunity and the pathognomonic morphological characteristics of type 1 diabetes demonstrated by instillation of heat-inactivated bacteria in the pancreatic duct of rats

Altered microvasculature in pancreatic islets from subjects with type 1 diabetes

Granlund, Louise; Hedin, Anders; Korsgren, Olle; Skog, Oskar et al.

Part of PLOS ONE, 2022

• DOI for Altered microvasculature in pancreatic islets from subjects with type 1 diabetes
• Download full text (pdf) of Altered microvasculature in pancreatic islets from subjects with type 1 diabetes

Characterisation of enterovirus RNA detected in the pancreas and other specimens of live patients with newly diagnosed type 1 diabetes in the DiViD study

Oikarinen, Sami; Krogvold, Lars; Edwin, Bjorn; Buanes, Trond et al.

Part of Diabetologia, p. 2491-2501, 2021

• DOI for Characterisation of enterovirus RNA detected in the pancreas and other specimens of live patients with newly diagnosed type 1 diabetes in the DiViD study
• Download full text (pdf) of Characterisation of enterovirus RNA detected in the pancreas and other specimens of live patients with newly diagnosed type 1 diabetes in the DiViD study

Histological and transcriptional characterization of the pancreatic acinar tissue in type 1 diabetes

Granlund, Louise; Hedin, Anders; Wahlhuetter, Miriam; Seiron, Peter et al.

Part of BMJ Open Diabetes Research & Care, 2021

• DOI for Histological and transcriptional characterization of the pancreatic acinar tissue in type 1 diabetes
• Download full text (pdf) of Histological and transcriptional characterization of the pancreatic acinar tissue in type 1 diabetes

Transcriptional analysis of islets of Langerhans from organ donors of different ages

Seiron, Peter; Stenwall, Per-Anton; Hedin, Anders; Granlund, Louise et al.

Part of PLOS ONE, 2021

• DOI for Transcriptional analysis of islets of Langerhans from organ donors of different ages

A decisive bridge between innate immunity and the pathognomonic morphological characteristics of type 1 diabetes demonstrated by instillation of heat-inactivated bacteria in the pancreatic duct of rats

Tegehall, Angie; Ingvast, Sofie; Melhus, Åsa; Skog, Oskar et al.

Part of Acta Diabetologica, p. 1011-1018, 2022

• DOI for A decisive bridge between innate immunity and the pathognomonic morphological characteristics of type 1 diabetes demonstrated by instillation of heat-inactivated bacteria in the pancreatic duct of rats
• Download full text (pdf) of A decisive bridge between innate immunity and the pathognomonic morphological characteristics of type 1 diabetes demonstrated by instillation of heat-inactivated bacteria in the pancreatic duct of rats

Altered microvasculature in pancreatic islets from subjects with type 1 diabetes

Granlund, Louise; Hedin, Anders; Korsgren, Olle; Skog, Oskar et al.

Part of PLOS ONE, 2022

• DOI for Altered microvasculature in pancreatic islets from subjects with type 1 diabetes
• Download full text (pdf) of Altered microvasculature in pancreatic islets from subjects with type 1 diabetes

Characterisation of enterovirus RNA detected in the pancreas and other specimens of live patients with newly diagnosed type 1 diabetes in the DiViD study

Oikarinen, Sami; Krogvold, Lars; Edwin, Bjorn; Buanes, Trond et al.

Part of Diabetologia, p. 2491-2501, 2021

• DOI for Characterisation of enterovirus RNA detected in the pancreas and other specimens of live patients with newly diagnosed type 1 diabetes in the DiViD study
• Download full text (pdf) of Characterisation of enterovirus RNA detected in the pancreas and other specimens of live patients with newly diagnosed type 1 diabetes in the DiViD study

Histological and transcriptional characterization of the pancreatic acinar tissue in type 1 diabetes

Granlund, Louise; Hedin, Anders; Wahlhuetter, Miriam; Seiron, Peter et al.

Part of BMJ Open Diabetes Research & Care, 2021

• DOI for Histological and transcriptional characterization of the pancreatic acinar tissue in type 1 diabetes
• Download full text (pdf) of Histological and transcriptional characterization of the pancreatic acinar tissue in type 1 diabetes

Transcriptional analysis of islets of Langerhans from organ donors of different ages

Seiron, Peter; Stenwall, Per-Anton; Hedin, Anders; Granlund, Louise et al.

Part of PLOS ONE, 2021

• DOI for Transcriptional analysis of islets of Langerhans from organ donors of different ages

Transcriptional profiles of human islet and exocrine endothelial cells in subjects with or without impaired glucose metabolism

Jonsson, Alexander; Hedin, Anders; Müller, Malin; Skog, Oskar et al.

Part of Scientific Reports, 2020

• DOI for Transcriptional profiles of human islet and exocrine endothelial cells in subjects with or without impaired glucose metabolism
• Download full text (pdf) of Transcriptional profiles of human islet and exocrine endothelial cells in subjects with or without impaired glucose metabolism

Multiplexing DNA methylation markers to detect circulating cell-free DNA derived from human pancreatic β cells

Neiman, Daniel; Gillis, David; Piyanzin, Sheina; Cohen, Daniel et al.

Part of JCI Insight, 2020

• DOI for Multiplexing DNA methylation markers to detect circulating cell-free DNA derived from human pancreatic β cells

On the dynamics of the human endocrine pancreas and potential consequences for the development of type 1 diabetes

Skog, Oskar; Korsgren, Olle

Part of Acta Diabetologica, p. 503-511, 2020

• DOI for On the dynamics of the human endocrine pancreas and potential consequences for the development of type 1 diabetes
• Download full text (pdf) of On the dynamics of the human endocrine pancreas and potential consequences for the development of type 1 diabetes

Protein Kinase R Is Constitutively Expressed in the Human Pancreas

Jonsson, Alexander; Yngve, Erik; Karlsson, Marie; Ingvast, Sofie et al.

Part of Journal of Histochemistry and Cytochemistry, p. 99-105, 2019

• DOI for Protein Kinase R Is Constitutively Expressed in the Human Pancreas

Characterisation of the endocrine pancreas in type 1 diabetes: islet size is maintained but islet number is markedly reduced

Seiron, Peter; Wiberg, Anna; Kuric, Enida; Krogvold, Lars et al.

Part of The journal of pathology. Clinical research, p. 248-255, 2019

• DOI for Characterisation of the endocrine pancreas in type 1 diabetes: islet size is maintained but islet number is markedly reduced
• Download full text (pdf) of Characterisation of the endocrine pancreas in type 1 diabetes: islet size is maintained but islet number is markedly reduced

Teplizumab in Relatives at Risk for Type 1 Diabetes

Korsgren, Olle; Skog, Oskar; Ludvigsson, Johnny

Part of New England Journal of Medicine, p. 1879-1880, 2019

• DOI for Teplizumab in Relatives at Risk for Type 1 Diabetes

Imagining a better future for all people with type 1 diabetes mellitus

Korsgren, Olle; Skyler, Jay S; Skog, Oskar; Sundberg, Frida et al.

Part of Nature Reviews Endocrinology, p. 623-624, 2019

• DOI for Imagining a better future for all people with type 1 diabetes mellitus

A whole organism small molecule screen identifies novel regulators of pancreatic endocrine development.

Helker, Christian S M; Mullapudi, Sri-Teja; Mueller, Laura M; Preussner, Jens et al.

Part of Development, 2019

• DOI for A whole organism small molecule screen identifies novel regulators of pancreatic endocrine development.

Characterization of host defense molecules in the human pancreas

Stenwall, Anton; Ingvast, Sofie; Skog, Oskar; Korsgren, Olle

Part of Islets, p. 89-101, 2019

• DOI for Characterization of host defense molecules in the human pancreas
• Download full text (pdf) of Characterization of host defense molecules in the human pancreas

Large enteroviral vaccination studies to prevent type 1 diabetes should be well founded and rely on scientific evidence

Skog, Oskar; Klingel, Karin; Roivainen, Merja; Korsgren, Olle

Part of Diabetologia, p. 1097-1099, 2019

• DOI for Large enteroviral vaccination studies to prevent type 1 diabetes should be well founded and rely on scientific evidence

Expression profiles of stress-related genes in islets from donors with progressively impaired glucose metabolism

Lundberg, Marcus; Stenwall, Per-Anton; Tegehall, Angie; Korsgren, Olle et al.

Part of Islets, p. 69-79, 2018

• DOI for Expression profiles of stress-related genes in islets from donors with progressively impaired glucose metabolism

No Evidence for Presence of Mucosal-Associated Invariant T Cells in the Insulitic Lesions in Patients Recently Diagnosed with Type 1 Diabetes

Kuric, Enida; Krogvold, Lars; Hanssen, Kristian F.; Dahl-Jorgensen, Knut et al.

Part of American Journal of Pathology, p. 1744-1748, 2018

• DOI for No Evidence for Presence of Mucosal-Associated Invariant T Cells in the Insulitic Lesions in Patients Recently Diagnosed with Type 1 Diabetes

Aetiology of type 1 diabetes: Physiological growth in children affects disease progression

Skog, Oskar; Korsgren, Olle

Part of Diabetes, obesity and metabolism, p. 775-785, 2018

• DOI for Aetiology of type 1 diabetes: Physiological growth in children affects disease progression

The density of parasympathetic axons is reduced in the exocrine pancreas of individuals recently diagnosed with type 1 diabetes

Lundberg, Marcus; Lindqvist, Andreas; Wierup, Nils; Krogvold, Lars et al.

Part of PLOS ONE, 2017

• DOI for The density of parasympathetic axons is reduced in the exocrine pancreas of individuals recently diagnosed with type 1 diabetes
• Download full text (pdf) of The density of parasympathetic axons is reduced in the exocrine pancreas of individuals recently diagnosed with type 1 diabetes

Insulitis in human diabetes: a histological evaluation of donor pancreases

Lundberg, Marcus; Seiron, Peter; Ingvast, Sofie; Korsgren, Olle et al.

Part of Diabetologia, p. 346-353, 2017

• DOI for Insulitis in human diabetes: a histological evaluation of donor pancreases
• Download full text (pdf) of Insulitis in human diabetes: a histological evaluation of donor pancreases

Demonstration of Tissue Resident Memory CD8 T Cells in Insulitic Lesions in Adult Patients with Recent-Onset Type 1 Diabetes

Kuric, Enida; Seiron, Peter; Krogvold, Lars; Edwin, Bjørn et al.

Part of American Journal of Pathology, p. 581-588, 2017

• DOI for Demonstration of Tissue Resident Memory CD8 T Cells in Insulitic Lesions in Adult Patients with Recent-Onset Type 1 Diabetes

Comment on Rodriguez-Calvo et al. Increase in Pancreatic Proinsulin and Preservation of β-Cell Mass in Autoantibody-Positive Donors Prior to Type 1 Diabetes Onset. Diabetes 2017;66:1334-1345

Skog, Oskar; Korsgren, Olle

Part of Diabetes, 2017

• DOI for Comment on Rodriguez-Calvo et al. Increase in Pancreatic Proinsulin and Preservation of β-Cell Mass in Autoantibody-Positive Donors Prior to Type 1 Diabetes Onset. Diabetes 2017;66:1334-1345

Presence of Human Herpesvirus 6B in the Pancreas of Subjects With and Without Type 1 Diabetes

Ericsson, Maja; Skog, Oskar

Part of Pancreas, p. 1341-1346, 2017

• DOI for Presence of Human Herpesvirus 6B in the Pancreas of Subjects With and Without Type 1 Diabetes

Characterization of resident lymphocytes in human pancreatic islets

Radenkovic, M; Uvebrant, K; Skog, Oskar; Sarmiento, L et al.

Part of Clinical and Experimental Immunology, p. 418-427, 2017

• DOI for Characterization of resident lymphocytes in human pancreatic islets

Re-addressing the 2013 consensus guidelines for the diagnosis of insulitis in human type 1 diabetes: is change necessary? Reply to Campbell-Thompson ML, Atkinson MA, Butler AE et al [letter].

Lundberg, Marcus; Seiron, Peter; Ingvast, Sofie; Korsgren, Olle et al.

Part of Diabetologia, p. 756-757, 2017

• DOI for Re-addressing the 2013 consensus guidelines for the diagnosis of insulitis in human type 1 diabetes: is change necessary? Reply to Campbell-Thompson ML, Atkinson MA, Butler AE et al [letter].

Expression of Interferon-Stimulated Genes in Insulitic Pancreatic Islets of Patients Recently Diagnosed With Type 1 Diabetes

Lundberg, Marcus; Krogvold, Lars; Kuric, Enida; Dahl-Jörgensen, Knut et al.

Part of Diabetes, p. 3104-3110, 2016

• DOI for Expression of Interferon-Stimulated Genes in Insulitic Pancreatic Islets of Patients Recently Diagnosed With Type 1 Diabetes

Insulitis and characterisation of infiltrating T cells in surgical pancreatic tail resections from patients at onset of type 1 diabetes

Krogvold, Lars; Wiberg, Anna; Edwin, Bjørn; Buanes, Trond et al.

Part of Diabetologia, p. 492-501, 2016

• DOI for Insulitis and characterisation of infiltrating T cells in surgical pancreatic tail resections from patients at onset of type 1 diabetes

Enterovirus infection of human islets of Langerhans affects beta-cell function resulting in disintegrated islets, decreased glucose stimulated insulin secretion and loss of Golgi structure

Hodik, Monika; Skog, Oskar; Lukinius, Agneta; Isaza-Correa, J. M. et al.

Part of BMJ OPEN DIABETES RESEARCH & CARE, 2016

• DOI for Enterovirus infection of human islets of Langerhans affects beta-cell function resulting in disintegrated islets, decreased glucose stimulated insulin secretion and loss of Golgi structure
• Download full text (pdf) of Enterovirus infection of human islets of Langerhans affects beta-cell function resulting in disintegrated islets, decreased glucose stimulated insulin secretion and loss of Golgi structure

Expression of Human Leukocyte Antigen Class I in Endocrine and Exocrine Pancreatic Tissue at Onset of Type 1 Diabetes

Skog, Oskar; Korsgren, Stella; Wiberg, Anna; Danielsson, Angelika et al.

Part of American Journal of Pathology, p. 129-138, 2015

• DOI for Expression of Human Leukocyte Antigen Class I in Endocrine and Exocrine Pancreatic Tissue at Onset of Type 1 Diabetes

Characterization of human organ donors testing positive for type 1 diabetes-associated autoantibodies

Wiberg, Anna; Granstam, Anna; Ingvast, Sofie; Harkonen, T. et al.

Part of Clinical and Experimental Immunology, p. 278-288, 2015

• DOI for Characterization of human organ donors testing positive for type 1 diabetes-associated autoantibodies

Detection of a low-grade enteroviral infection in the islets of Langerhans of living patients newly diagnosed with type 1 diabetes

Krogvold, Lars; Edwin, Bjørn; Buanes, Trond; Frisk, Gun et al.

Part of Diabetes, p. 1682-1687, 2015

• DOI for Detection of a low-grade enteroviral infection in the islets of Langerhans of living patients newly diagnosed with type 1 diabetes

Function of Isolated Pancreatic Islets From Patients at Onset of Type 1 Diabetes: Insulin Secretion Can Be Restored After Some Days in a Nondiabetogenic Environment In Vitro: Results From the DiViD Study

Krogvold, Lars; Skog, Oskar; Sundström, Görel; Edwin, Bjorn et al.

Part of Diabetes, p. 2506-2512, 2015

• DOI for Function of Isolated Pancreatic Islets From Patients at Onset of Type 1 Diabetes: Insulin Secretion Can Be Restored After Some Days in a Nondiabetogenic Environment In Vitro: Results From the DiViD Study

Gene expression analysis of human islets in a subject at onset of type 1 diabetes

Hopfgarten, Johan; Stenwall, Per-Anton; Wiberg, Anna; Anagandula, Mahesh et al.

Part of Acta Diabetologica, p. 199-204, 2014

• DOI for Gene expression analysis of human islets in a subject at onset of type 1 diabetes

Evaluation of RT-PCR and immunohistochemistry as tools for detection of enterovirus in the human pancreas and islets of Langerhans

Skog, Oskar; Ingvast, Sofie; Korsgren, Olle

Part of Journal of Clinical Virology, p. 242-247, 2014

• DOI for Evaluation of RT-PCR and immunohistochemistry as tools for detection of enterovirus in the human pancreas and islets of Langerhans

Human enterovirus species B in ileocecal Crohn's disease

Nyström, Niklas; Berg, Tove; Lundin, Elin; Skog, Oskar et al.

Part of Clinical and Translational Gastroenterology, 2013

• DOI for Human enterovirus species B in ileocecal Crohn's disease
• Download full text (pdf) of Human enterovirus species B in ileocecal Crohn's disease

Modulation of Innate Immunity in Human Pancreatic Islets Infected With Enterovirus In Vitro

Skog, Oskar; Korsgren, Olle; Frisk, Gun

Part of Journal of Medical Virology, p. 658-664, 2011

• DOI for Modulation of Innate Immunity in Human Pancreatic Islets Infected With Enterovirus In Vitro

Antiviral effect of nicotinamide on enterovirus-infected human islets in vitro: effect on virus replication and chemokine secretion

Moëll, Annika; Skog, Oskar; Åhlin, Erik; Korsgren, Olle et al.

Part of Journal of Medical Virology, p. 1082-1087, 2009

• DOI for Antiviral effect of nicotinamide on enterovirus-infected human islets in vitro: effect on virus replication and chemokine secretion

Revisiting the notion of type 1 diabetes being a T-cell-mediated autoimmune disease

Skog, Oskar; Korsgren, Stella; Melhus, Åsa; Korsgren, Olle

Part of Current Opinion In Endocrinology Diabetes And Obesity, p. 118-123, 2013

• DOI for Revisiting the notion of type 1 diabetes being a T-cell-mediated autoimmune disease

Effects of Enterovirus Infection on Innate Immunity and Beta Cell Function in Human Islets of Langerhans

Skog, Oskar

2012

• Download full text (pdf) of Effects of Enterovirus Infection on Innate Immunity and Beta Cell Function in Human Islets of Langerhans

Enterovirus Infection Reduces Beta-cell Function and Leads to Decreased Glucose Stimulated Insulin Secretion in Dissociated but not In Intact Pancreatic Human Islets

Skog, Oskar; Hodik, Monika; Korsgren, Olle; Frisk, Gun

Ongoing Pathogenic Processes in the Pancreas at Onset of Type 1 Diabetes in Humans

Skog, Oskar; Hodik, Monika; Lukinius, Agneta; Korsgren, Olle et al.