Oskar Skog

Altered microvasculature in pancreatic islets from subjects with type 1 diabetes

Granlund, Louise; Hedin, Anders; Korsgren, Olle; Skog, Oskar et al.

Part of PLOS ONE, 2022

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A decisive bridge between innate immunity and the pathognomonic morphological characteristics of type 1 diabetes demonstrated by instillation of heat-inactivated bacteria in the pancreatic duct of rats

Tegehall, Angie; Ingvast, Sofie; Melhus, Åsa; Skog, Oskar et al.

Part of Acta Diabetologica, p. 1011-1018, 2022

• DOI for A decisive bridge between innate immunity and the pathognomonic morphological characteristics of type 1 diabetes demonstrated by instillation of heat-inactivated bacteria in the pancreatic duct of rats
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Transcriptional analysis of islets of Langerhans from organ donors of different ages

Seiron, Peter; Stenwall, Anton; Hedin, Anders; Granlund, Louise et al.

Part of PLOS ONE, 2021

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Characterisation of enterovirus RNA detected in the pancreas and other specimens of live patients with newly diagnosed type 1 diabetes in the DiViD study

Oikarinen, Sami; Krogvold, Lars; Edwin, Bjorn; Buanes, Trond et al.

Part of Diabetologia, p. 2491-2501, 2021

• DOI for Characterisation of enterovirus RNA detected in the pancreas and other specimens of live patients with newly diagnosed type 1 diabetes in the DiViD study
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Histological and transcriptional characterization of the pancreatic acinar tissue in type 1 diabetes

Granlund, Louise; Hedin, Anders; Wahlhuetter, Miriam; Seiron, Peter et al.

Part of BMJ Open Diabetes Research & Care, 2021

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Altered microvasculature in pancreatic islets from subjects with type 1 diabetes

Granlund, Louise; Hedin, Anders; Korsgren, Olle; Skog, Oskar et al.

Part of PLOS ONE, 2022

• DOI for Altered microvasculature in pancreatic islets from subjects with type 1 diabetes
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A decisive bridge between innate immunity and the pathognomonic morphological characteristics of type 1 diabetes demonstrated by instillation of heat-inactivated bacteria in the pancreatic duct of rats

Tegehall, Angie; Ingvast, Sofie; Melhus, Åsa; Skog, Oskar et al.

Part of Acta Diabetologica, p. 1011-1018, 2022

• DOI for A decisive bridge between innate immunity and the pathognomonic morphological characteristics of type 1 diabetes demonstrated by instillation of heat-inactivated bacteria in the pancreatic duct of rats
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Transcriptional analysis of islets of Langerhans from organ donors of different ages

Seiron, Peter; Stenwall, Anton; Hedin, Anders; Granlund, Louise et al.

Part of PLOS ONE, 2021

• DOI for Transcriptional analysis of islets of Langerhans from organ donors of different ages
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Characterisation of enterovirus RNA detected in the pancreas and other specimens of live patients with newly diagnosed type 1 diabetes in the DiViD study

Oikarinen, Sami; Krogvold, Lars; Edwin, Bjorn; Buanes, Trond et al.

Part of Diabetologia, p. 2491-2501, 2021

• DOI for Characterisation of enterovirus RNA detected in the pancreas and other specimens of live patients with newly diagnosed type 1 diabetes in the DiViD study
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Histological and transcriptional characterization of the pancreatic acinar tissue in type 1 diabetes

Granlund, Louise; Hedin, Anders; Wahlhuetter, Miriam; Seiron, Peter et al.

Part of BMJ Open Diabetes Research & Care, 2021

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Transcriptional profiles of human islet and exocrine endothelial cells in subjects with or without impaired glucose metabolism

Jonsson, Alexander; Hedin, Anders; Müller, Malin; Skog, Oskar et al.

Part of Scientific Reports, 2020

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Multiplexing DNA methylation markers to detect circulating cell-free DNA derived from human pancreatic β cells

Neiman, Daniel; Gillis, David; Piyanzin, Sheina; Cohen, Daniel et al.

Part of JCI Insight, 2020

• DOI for Multiplexing DNA methylation markers to detect circulating cell-free DNA derived from human pancreatic β cells

On the dynamics of the human endocrine pancreas and potential consequences for the development of type 1 diabetes

Skog, Oskar; Korsgren, Olle

Part of Acta Diabetologica, p. 503-511, 2020

• DOI for On the dynamics of the human endocrine pancreas and potential consequences for the development of type 1 diabetes
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Characterization of host defense molecules in the human pancreas

Stenwall, Anton; Ingvast, Sofie; Skog, Oskar; Korsgren, Olle

Part of Islets, p. 89-101, 2019

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Protein Kinase R Is Constitutively Expressed in the Human Pancreas

Jonsson, Alexander; Yngve, Erik; Karlsson, Marie; Ingvast, Sofie et al.

Part of Journal of Histochemistry and Cytochemistry, p. 99-105, 2019

• DOI for Protein Kinase R Is Constitutively Expressed in the Human Pancreas

Characterisation of the endocrine pancreas in type 1 diabetes: islet size is maintained but islet number is markedly reduced

Seiron, Peter; Wiberg, Anna; Kuric, Enida; Krogvold, Lars et al.

Part of The journal of pathology. Clinical research, p. 248-255, 2019

• DOI for Characterisation of the endocrine pancreas in type 1 diabetes: islet size is maintained but islet number is markedly reduced
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Teplizumab in Relatives at Risk for Type 1 Diabetes

Korsgren, Olle; Skog, Oskar; Ludvigsson, Johnny

Part of New England Journal of Medicine, p. 1879-1880, 2019

• DOI for Teplizumab in Relatives at Risk for Type 1 Diabetes

Imagining a better future for all people with type 1 diabetes mellitus

Korsgren, Olle; Skyler, Jay S; Skog, Oskar; Sundberg, Frida et al.

Part of Nature Reviews Endocrinology, p. 623-624, 2019

• DOI for Imagining a better future for all people with type 1 diabetes mellitus

A whole organism small molecule screen identifies novel regulators of pancreatic endocrine development.

Helker, Christian S M; Mullapudi, Sri-Teja; Mueller, Laura M; Preussner, Jens et al.

Part of Development, 2019

• DOI for A whole organism small molecule screen identifies novel regulators of pancreatic endocrine development.

Large enteroviral vaccination studies to prevent type 1 diabetes should be well founded and rely on scientific evidence

Skog, Oskar; Klingel, Karin; Roivainen, Merja; Korsgren, Olle

Part of Diabetologia, p. 1097-1099, 2019

• DOI for Large enteroviral vaccination studies to prevent type 1 diabetes should be well founded and rely on scientific evidence

Expression profiles of stress-related genes in islets from donors with progressively impaired glucose metabolism

Lundberg, Marcus; Stenwall, Anton; Tegehall, Angie; Korsgren, Olle et al.

Part of Islets, p. 69-79, 2018

• DOI for Expression profiles of stress-related genes in islets from donors with progressively impaired glucose metabolism
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No Evidence for Presence of Mucosal-Associated Invariant T Cells in the Insulitic Lesions in Patients Recently Diagnosed with Type 1 Diabetes

Kuric, Enida; Krogvold, Lars; Hanssen, Kristian F.; Dahl-Jorgensen, Knut et al.

Part of American Journal of Pathology, p. 1744-1748, 2018

• DOI for No Evidence for Presence of Mucosal-Associated Invariant T Cells in the Insulitic Lesions in Patients Recently Diagnosed with Type 1 Diabetes

Aetiology of type 1 diabetes: Physiological growth in children affects disease progression

Skog, Oskar; Korsgren, Olle

Part of Diabetes, obesity and metabolism, p. 775-785, 2018

• DOI for Aetiology of type 1 diabetes: Physiological growth in children affects disease progression

The density of parasympathetic axons is reduced in the exocrine pancreas of individuals recently diagnosed with type 1 diabetes

Lundberg, Marcus; Lindqvist, Andreas; Wierup, Nils; Krogvold, Lars et al.

Part of PLOS ONE, 2017

• DOI for The density of parasympathetic axons is reduced in the exocrine pancreas of individuals recently diagnosed with type 1 diabetes
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Insulitis in human diabetes: a histological evaluation of donor pancreases

Lundberg, Marcus; Seiron, Peter; Ingvast, Sofie; Korsgren, Olle et al.

Part of Diabetologia, p. 346-353, 2017

• DOI for Insulitis in human diabetes: a histological evaluation of donor pancreases
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Demonstration of Tissue Resident Memory CD8 T Cells in Insulitic Lesions in Adult Patients with Recent-Onset Type 1 Diabetes

Kuric, Enida; Seiron, Peter; Krogvold, Lars; Edwin, Bjørn et al.

Part of American Journal of Pathology, p. 581-588, 2017

• DOI for Demonstration of Tissue Resident Memory CD8 T Cells in Insulitic Lesions in Adult Patients with Recent-Onset Type 1 Diabetes

Comment on Rodriguez-Calvo et al. Increase in Pancreatic Proinsulin and Preservation of β-Cell Mass in Autoantibody-Positive Donors Prior to Type 1 Diabetes Onset. Diabetes 2017;66:1334-1345

Skog, Oskar; Korsgren, Olle

Part of Diabetes, 2017

• DOI for Comment on Rodriguez-Calvo et al. Increase in Pancreatic Proinsulin and Preservation of β-Cell Mass in Autoantibody-Positive Donors Prior to Type 1 Diabetes Onset. Diabetes 2017;66:1334-1345

Presence of Human Herpesvirus 6B in the Pancreas of Subjects With and Without Type 1 Diabetes

Ericsson, Maja; Skog, Oskar

Part of Pancreas, p. 1341-1346, 2017

• DOI for Presence of Human Herpesvirus 6B in the Pancreas of Subjects With and Without Type 1 Diabetes

Characterization of resident lymphocytes in human pancreatic islets

Radenkovic, M; Uvebrant, K; Skog, Oskar; Sarmiento, L et al.

Part of Clinical and Experimental Immunology, p. 418-427, 2017

• DOI for Characterization of resident lymphocytes in human pancreatic islets

Re-addressing the 2013 consensus guidelines for the diagnosis of insulitis in human type 1 diabetes: is change necessary? Reply to Campbell-Thompson ML, Atkinson MA, Butler AE et al [letter].

Lundberg, Marcus; Seiron, Peter; Ingvast, Sofie; Korsgren, Olle et al.

Part of Diabetologia, p. 756-757, 2017

• DOI for Re-addressing the 2013 consensus guidelines for the diagnosis of insulitis in human type 1 diabetes: is change necessary? Reply to Campbell-Thompson ML, Atkinson MA, Butler AE et al [letter].

Expression of Interferon-Stimulated Genes in Insulitic Pancreatic Islets of Patients Recently Diagnosed With Type 1 Diabetes

Lundberg, Marcus; Krogvold, Lars; Kuric, Enida; Dahl-Jörgensen, Knut et al.

Part of Diabetes, p. 3104-3110, 2016

• DOI for Expression of Interferon-Stimulated Genes in Insulitic Pancreatic Islets of Patients Recently Diagnosed With Type 1 Diabetes

Insulitis and characterisation of infiltrating T cells in surgical pancreatic tail resections from patients at onset of type 1 diabetes

Krogvold, Lars; Wiberg, Anna; Edwin, Bjørn; Buanes, Trond et al.

Part of Diabetologia, p. 492-501, 2016

• DOI for Insulitis and characterisation of infiltrating T cells in surgical pancreatic tail resections from patients at onset of type 1 diabetes

Enterovirus infection of human islets of Langerhans affects beta-cell function resulting in disintegrated islets, decreased glucose stimulated insulin secretion and loss of Golgi structure

Hodik, Monika; Skog, Oskar; Lukinius, Agneta; Isaza-Correa, J. M. et al.

Part of BMJ OPEN DIABETES RESEARCH & CARE, 2016

• DOI for Enterovirus infection of human islets of Langerhans affects beta-cell function resulting in disintegrated islets, decreased glucose stimulated insulin secretion and loss of Golgi structure
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Expression of Human Leukocyte Antigen Class I in Endocrine and Exocrine Pancreatic Tissue at Onset of Type 1 Diabetes

Skog, Oskar; Korsgren, Stella; Wiberg, Anna; Danielsson, Angelika et al.

Part of American Journal of Pathology, p. 129-138, 2015

• DOI for Expression of Human Leukocyte Antigen Class I in Endocrine and Exocrine Pancreatic Tissue at Onset of Type 1 Diabetes

Characterization of human organ donors testing positive for type 1 diabetes-associated autoantibodies

Wiberg, Anna; Granstam, Anna; Ingvast, Sofie; Harkonen, T. et al.

Part of Clinical and Experimental Immunology, p. 278-288, 2015

• DOI for Characterization of human organ donors testing positive for type 1 diabetes-associated autoantibodies

Detection of a low-grade enteroviral infection in the islets of Langerhans of living patients newly diagnosed with type 1 diabetes

Krogvold, Lars; Edwin, Bjørn; Buanes, Trond; Frisk, Gun et al.

Part of Diabetes, p. 1682-1687, 2015

• DOI for Detection of a low-grade enteroviral infection in the islets of Langerhans of living patients newly diagnosed with type 1 diabetes

Function of Isolated Pancreatic Islets From Patients at Onset of Type 1 Diabetes: Insulin Secretion Can Be Restored After Some Days in a Nondiabetogenic Environment In Vitro: Results From the DiViD Study

Krogvold, Lars; Skog, Oskar; Sundström, Görel; Edwin, Bjorn et al.

Part of Diabetes, p. 2506-2512, 2015

• DOI for Function of Isolated Pancreatic Islets From Patients at Onset of Type 1 Diabetes: Insulin Secretion Can Be Restored After Some Days in a Nondiabetogenic Environment In Vitro: Results From the DiViD Study

Gene expression analysis of human islets in a subject at onset of type 1 diabetes

Hopfgarten, Johan; Stenwall, Per-Anton; Wiberg, Anna; Anagandula, Mahesh et al.

Part of Acta Diabetologica, p. 199-204, 2014

• DOI for Gene expression analysis of human islets in a subject at onset of type 1 diabetes

Evaluation of RT-PCR and immunohistochemistry as tools for detection of enterovirus in the human pancreas and islets of Langerhans

Skog, Oskar; Ingvast, Sofie; Korsgren, Olle

Part of Journal of Clinical Virology, p. 242-247, 2014

• DOI for Evaluation of RT-PCR and immunohistochemistry as tools for detection of enterovirus in the human pancreas and islets of Langerhans

Human enterovirus species B in ileocecal Crohn's disease

Nyström, Niklas; Berg, Tove; Lundin, Elin; Skog, Oskar et al.

Part of Clinical and Translational Gastroenterology, 2013

• DOI for Human enterovirus species B in ileocecal Crohn's disease
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Modulation of Innate Immunity in Human Pancreatic Islets Infected With Enterovirus In Vitro

Skog, Oskar; Korsgren, Olle; Frisk, Gun

Part of Journal of Medical Virology, p. 658-664, 2011

• DOI for Modulation of Innate Immunity in Human Pancreatic Islets Infected With Enterovirus In Vitro

Antiviral effect of nicotinamide on enterovirus-infected human islets in vitro: effect on virus replication and chemokine secretion

Moëll, Annika; Skog, Oskar; Åhlin, Erik; Korsgren, Olle et al.

Part of Journal of Medical Virology, p. 1082-1087, 2009

• DOI for Antiviral effect of nicotinamide on enterovirus-infected human islets in vitro: effect on virus replication and chemokine secretion

Revisiting the notion of type 1 diabetes being a T-cell-mediated autoimmune disease

Skog, Oskar; Korsgren, Stella; Melhus, Åsa; Korsgren, Olle

Part of Current Opinion In Endocrinology Diabetes And Obesity, p. 118-123, 2013

• DOI for Revisiting the notion of type 1 diabetes being a T-cell-mediated autoimmune disease

Effects of Enterovirus Infection on Innate Immunity and Beta Cell Function in Human Islets of Langerhans

Skog, Oskar

2012

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Enterovirus Infection Reduces Beta-cell Function and Leads to Decreased Glucose Stimulated Insulin Secretion in Dissociated but not In Intact Pancreatic Human Islets

Skog, Oskar; Hodik, Monika; Korsgren, Olle; Frisk, Gun

Ongoing Pathogenic Processes in the Pancreas at Onset of Type 1 Diabetes in Humans

Skog, Oskar; Hodik, Monika; Lukinius, Agneta; Korsgren, Olle et al.