Gunilla Westermark
Professor at Department of Medical Cell Biology; Research Group Gunilla Westermark
- E-mail:
- gunilla.westermark@mcb.uu.se
- Visiting address:
- BMC
Husargatan 3
751 23 Uppsala - Postal address:
- Box 571
751 23 UPPSALA
Publications
Recent publications
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Part of Amyloid, p. 125-134, 2026
- DOI for Lysozyme as an amyloid fibril protein together with transthyretin in the ligamentum flavum in association with lumbar spinal stenosis
- Download full text (pdf) of Lysozyme as an amyloid fibril protein together with transthyretin in the ligamentum flavum in association with lumbar spinal stenosis
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Part of Diabetologia, p. 436-450, 2026
- DOI for Bri2 BRICHOS domain inhibits IAPP amyloid formation and improves beta cell function in stem cell-derived islets under metabolic stress
- Download full text (pdf) of Bri2 BRICHOS domain inhibits IAPP amyloid formation and improves beta cell function in stem cell-derived islets under metabolic stress
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Part of Frontiers in Cellular Neuroscience, 2025
- DOI for Rodent islet amyloid polypeptide (IAPP) selectively enhances GABAA receptor-mediated neuronal inhibition in mouse ventral but not dorsal hippocampal dentate gyrus granule cells
- Download full text (pdf) of Rodent islet amyloid polypeptide (IAPP) selectively enhances GABAA receptor-mediated neuronal inhibition in mouse ventral but not dorsal hippocampal dentate gyrus granule cells
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The question of strains in AA amyloidosis
Part of Scientific Reports, 2025
- DOI for The question of strains in AA amyloidosis
- Download full text (pdf) of The question of strains in AA amyloidosis
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Efficient Vascular and Neural Engraftment of Stem Cell–Derived Islets
Part of Diabetes, p. 1127-1139, 2024
All publications
Articles in journal
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Part of Amyloid, p. 125-134, 2026
- DOI for Lysozyme as an amyloid fibril protein together with transthyretin in the ligamentum flavum in association with lumbar spinal stenosis
- Download full text (pdf) of Lysozyme as an amyloid fibril protein together with transthyretin in the ligamentum flavum in association with lumbar spinal stenosis
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Part of Diabetologia, p. 436-450, 2026
- DOI for Bri2 BRICHOS domain inhibits IAPP amyloid formation and improves beta cell function in stem cell-derived islets under metabolic stress
- Download full text (pdf) of Bri2 BRICHOS domain inhibits IAPP amyloid formation and improves beta cell function in stem cell-derived islets under metabolic stress
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Part of Frontiers in Cellular Neuroscience, 2025
- DOI for Rodent islet amyloid polypeptide (IAPP) selectively enhances GABAA receptor-mediated neuronal inhibition in mouse ventral but not dorsal hippocampal dentate gyrus granule cells
- Download full text (pdf) of Rodent islet amyloid polypeptide (IAPP) selectively enhances GABAA receptor-mediated neuronal inhibition in mouse ventral but not dorsal hippocampal dentate gyrus granule cells
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The question of strains in AA amyloidosis
Part of Scientific Reports, 2025
- DOI for The question of strains in AA amyloidosis
- Download full text (pdf) of The question of strains in AA amyloidosis
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Efficient Vascular and Neural Engraftment of Stem Cell–Derived Islets
Part of Diabetes, p. 1127-1139, 2024
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The ASC inflammasome adapter governs SAA-derived protein aggregation in inflammatory amyloidosis
Part of EMBO Molecular Medicine, p. 2024-2042, 2024
- DOI for The ASC inflammasome adapter governs SAA-derived protein aggregation in inflammatory amyloidosis
- Download full text (pdf) of The ASC inflammasome adapter governs SAA-derived protein aggregation in inflammatory amyloidosis
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Insulin release from isolated cat islets of Langerhans
Part of Domestic Animal Endocrinology, 2024
- DOI for Insulin release from isolated cat islets of Langerhans
- Download full text (pdf) of Insulin release from isolated cat islets of Langerhans
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CLEC11A improves insulin secretion and promotes cell proliferation in human beta-cells
Part of Journal of Molecular Endocrinology, 2023
- DOI for CLEC11A improves insulin secretion and promotes cell proliferation in human beta-cells
- Download full text (pdf) of CLEC11A improves insulin secretion and promotes cell proliferation in human beta-cells
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Phosphorylated α-synuclein in skin Schwann cells: a new biomarker for multiple system atrophy
Part of Brain, p. 1065-1074, 2023
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Studies on alpha-synuclein and islet amyloid polypeptide interaction
Part of Frontiers in Molecular Biosciences, 2023
- DOI for Studies on alpha-synuclein and islet amyloid polypeptide interaction
- Download full text (pdf) of Studies on alpha-synuclein and islet amyloid polypeptide interaction
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Part of Upsala Journal of Medical Sciences, 2022
- DOI for Tissue-based diagnosis of systemic amyloidosis: Experience of the informal diagnostic center at Uppsala University Hospital
- Download full text (pdf) of Tissue-based diagnosis of systemic amyloidosis: Experience of the informal diagnostic center at Uppsala University Hospital
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Amyloid fibril structure from the vascular variant of systemic AA amyloidosis
Part of Nature Communications, 2022
- DOI for Amyloid fibril structure from the vascular variant of systemic AA amyloidosis
- Download full text (pdf) of Amyloid fibril structure from the vascular variant of systemic AA amyloidosis
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Part of Journal of Enzyme Inhibition and Medicinal Chemistry, p. 517-524, 2021
- DOI for Washingtonia filifera seed extracts inhibit the islet amyloid polypeptide fibrils formations and alpha-amylase and alpha-glucosidase activity
- Download full text (pdf) of Washingtonia filifera seed extracts inhibit the islet amyloid polypeptide fibrils formations and alpha-amylase and alpha-glucosidase activity
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AA amyloid in human food chain is a possible biohazard
Part of Scientific Reports, 2021
- DOI for AA amyloid in human food chain is a possible biohazard
- Download full text (pdf) of AA amyloid in human food chain is a possible biohazard
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Enhanced detection of ATTR amyloid using a nanofibril-based assay
Part of Amyloid, p. 158-167, 2021
- DOI for Enhanced detection of ATTR amyloid using a nanofibril-based assay
- Download full text (pdf) of Enhanced detection of ATTR amyloid using a nanofibril-based assay
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Part of International Journal of Biological Macromolecules, p. 428-435, 2021
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Part of American Journal of Transplantation, p. 2090-2099, 2021
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The Amyloid Forming Peptides Islet Amyloid Polypeptide and Amyloid β Interact at the Molecular Level
Part of International Journal of Molecular Sciences, 2021
- DOI for The Amyloid Forming Peptides Islet Amyloid Polypeptide and Amyloid β Interact at the Molecular Level
- Download full text (pdf) of The Amyloid Forming Peptides Islet Amyloid Polypeptide and Amyloid β Interact at the Molecular Level
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Part of Nature Communications, 2019
- DOI for Cryo-EM fibril structures from systemic AA amyloidosis reveal the species complementarity of pathological amyloids
- Download full text (pdf) of Cryo-EM fibril structures from systemic AA amyloidosis reveal the species complementarity of pathological amyloids
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3D analysis of human islet amyloid polypeptide crystalline structures in Drosophila melanogaster
Part of PLOS ONE, 2019
- DOI for 3D analysis of human islet amyloid polypeptide crystalline structures in Drosophila melanogaster
- Download full text (pdf) of 3D analysis of human islet amyloid polypeptide crystalline structures in Drosophila melanogaster
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Lipid membranes accelerate amyloid formation in the mouse model of AA amyloidosis
Part of Amyloid, p. 34-44, 2019
- DOI for Lipid membranes accelerate amyloid formation in the mouse model of AA amyloidosis
- Download full text (pdf) of Lipid membranes accelerate amyloid formation in the mouse model of AA amyloidosis
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Part of Proceedings of the National Academy of Sciences of the United States of America, 2018
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Noncerebral Amyloidoses: Aspects on Seeding, Cross-Seeding, and Transmission
Part of Cold Spring Harbor Perspectives in Medicine, 2018
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Part of American Journal of Transplantation, p. 1735-1744, 2018
- DOI for Transplantation of macroencapsulated human islets within the bioartificial pancreas βAir to patients with type 1 diabetes mellitus
- Download full text (pdf) of Transplantation of macroencapsulated human islets within the bioartificial pancreas βAir to patients with type 1 diabetes mellitus
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Protofibrillar and Fibrillar Amyloid-beta Binding Proteins in Cerebrospinal Fluid
Part of Journal of Alzheimer's Disease, p. 1053-1064, 2018
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The Cryo-EM Method Micro-ED Structure Determination of Type II Diabetes-Related Protein Segments
Part of Biophysical Journal, 2017
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Islet amyloid deposits preferentially in the highly functional and most blood-perfused islets.
Part of Endocrine Connections, p. 458-468, 2017
- DOI for Islet amyloid deposits preferentially in the highly functional and most blood-perfused islets.
- Download full text (pdf) of Islet amyloid deposits preferentially in the highly functional and most blood-perfused islets.
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Part of eLIFE, 2017
- DOI for Atomic structures of fibrillar segments of hIAPP suggest tightly mated beta-sheets are important or cytotoxicity
- Download full text (pdf) of Atomic structures of fibrillar segments of hIAPP suggest tightly mated beta-sheets are important or cytotoxicity
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Human Astrocytes Transfer Aggregated Alpha-Synuclein via Tunneling Nanotubes
Part of Journal of Neuroscience, p. 11835-11853, 2017
- DOI for Human Astrocytes Transfer Aggregated Alpha-Synuclein via Tunneling Nanotubes
- Download full text (pdf) of Human Astrocytes Transfer Aggregated Alpha-Synuclein via Tunneling Nanotubes
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Systemic AA amyloidosis in the red fox (Vulpes vulpes)
Part of Protein Science, p. 2312-2318, 2017
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Seed-dependent templating of murine AA amyloidosis
Part of Amyloid, p. 140-141, 2017
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Islet amyloid in recent-onset type 1 diabetes-the DiViD study
Part of Upsala Journal of Medical Sciences, p. 201-203, 2017
- DOI for Islet amyloid in recent-onset type 1 diabetes-the DiViD study
- Download full text (pdf) of Islet amyloid in recent-onset type 1 diabetes-the DiViD study
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Part of Upsala Journal of Medical Sciences, p. 149-159, 2017
- DOI for Addition of exogenous sodium palmitate increases the IAPP/insulin mRNA ratio via GPR40 in human EndoC-beta H1 cells
- Download full text (pdf) of Addition of exogenous sodium palmitate increases the IAPP/insulin mRNA ratio via GPR40 in human EndoC-beta H1 cells
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The human serum protein C4b-binding protein inhibits pancreatic IAPP-induced inflammasome activation
Part of Diabetologia, p. 1522-1533, 2017
- DOI for The human serum protein C4b-binding protein inhibits pancreatic IAPP-induced inflammasome activation
- Download full text (pdf) of The human serum protein C4b-binding protein inhibits pancreatic IAPP-induced inflammasome activation
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Part of ACS Medicinal Chemistry Letters, p. 368-373, 2016
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Electron tomography reveals the fibril structure and lipid interactions in amyloid deposits
Part of Proceedings of the National Academy of Sciences of the United States of America, p. 5604-5609, 2016
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Part of Immunobiology, p. 1162-1162, 2016
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C4b-binding Protein Protects -Cells from Islet Amyloid Polypeptide-induced Cytotoxicity
Part of Journal of Biological Chemistry, p. 21644-21655, 2016
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Part of Amyloid, p. 98-108, 2016
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Part of American Journal of Pathology, p. 834-846, 2015
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C4BP inhibits IAPP-mediated inflammasome activation in type 2 diabetes
Part of Molecular Immunology, p. 152-152, 2015
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Eighty years of research on islet amyloidosis in Uppsala
Part of Upsala Journal of Medical Sciences, p. 117-123, 2015
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Part of Journal of Biological Chemistry, p. 15121-15132, 2015
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High Plasma Levels of Islet Amyloid Polypeptide in Young with New-Onset of Type 1 Diabetes Mellitus
Part of PLOS ONE, 2014
- DOI for High Plasma Levels of Islet Amyloid Polypeptide in Young with New-Onset of Type 1 Diabetes Mellitus
- Download full text (pdf) of High Plasma Levels of Islet Amyloid Polypeptide in Young with New-Onset of Type 1 Diabetes Mellitus
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Transthyretin-derived amyloidosis: Probably a common cause of lumbar spinal stenosis
Part of Upsala Journal of Medical Sciences, p. 223-228, 2014
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C4b-binding protein inhibits islet amyloid polypeptide-induced cytotoxicity and inflammation
Part of Molecular Immunology, p. 224-224, 2014
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Part of Disease Models and Mechanisms, p. 659-665, 2014
- DOI for The chaperone domain BRICHOS prevents CNS toxicity of amyloid-beta peptide in Drosophila melanogaster
- Download full text (pdf) of The chaperone domain BRICHOS prevents CNS toxicity of amyloid-beta peptide in Drosophila melanogaster
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Part of Cell Transplantation, p. 139-151, 2014
- DOI for Birth and Death of Human beta-Cells in Pancreases From Cadaver Donors, Autopsies, Surgical Specimens, and Islets Transplanted Into Mice
- Download full text (pdf) of Birth and Death of Human beta-Cells in Pancreases From Cadaver Donors, Autopsies, Surgical Specimens, and Islets Transplanted Into Mice
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Part of PLOS ONE, 2013
- DOI for Depletion of Spleen Macrophages Delays AA Amyloid Development: A Study Performed in the Rapid Mouse Model of AA Amyloidosis
- Download full text (pdf) of Depletion of Spleen Macrophages Delays AA Amyloid Development: A Study Performed in the Rapid Mouse Model of AA Amyloidosis
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Efficient Amyloid A Clearance in the Absence of Immunoglobulins and Complement Factors
Part of American Journal of Pathology, p. 1297-1307, 2013
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Part of Journal of labelled compounds & radiopharmaceuticals, 2013
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Part of Journal of Biological Chemistry, p. 10824-10833, 2012
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Part of Archives of Dermatological Research, p. 377-386, 2012
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Part of Neurobiology of Aging, 2012
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Extensive amyloid formation in transplanted microencapsulated mouse and human islets
Part of Amyloid, p. 87-93, 2012
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Further Evidence for Amyloid Deposition in Clinical Pancreatic Islet Grafts
Part of Transplantation, p. 219-223, 2012
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AA-Amyloid is cleared by endogenous immunological mechanisms
Part of Amyloid, p. 138-145, 2012
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Complement inhibitor C4b-binding protein is involved in protein AA amyloidosis
Part of Immunobiology, p. 1158-1158, 2012
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Part of American Journal of Pathology, p. 2286-2298, 2011
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Part of Amyloid, p. 47-52, 2011
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Part of American Journal of Pathology, p. 2632-2640, 2011
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Part of PloS one, 2009
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Part of Scandinavian Journal of Immunology, p. 535-540, 2009
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Part of Experimental diabetes research, p. 528354, 2008
Articles, review/survey
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Part of Chemical Reviews, p. 1845-1893, 2021
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Current and future treatment of amyloid diseases
Part of Journal of Internal Medicine, p. 177-202, 2016
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Islet Amyloid Polypeptide and Diabetes
Part of Current protein and peptide science, p. 330-337, 2013
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Islet amyloid polypeptide, islet amyloid, and diabetes mellitus
Part of Physiological Reviews, p. 795-826, 2011
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Part of The FEBS Journal, p. 3918-3929, 2011
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Prion-like aggregates: infectious agents in human disease
Part of Trends in Molecular Medicine, p. 501-507, 2010
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Serum amyloid A and protein AA: molecular mechanisms of a transmissible amyloidosis
Part of FEBS Letters, p. 2685-2690, 2009
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Part of Experimental diabetes research, p. 562985, 2008
Chapters in book
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AA Amyloidosis: Pathogenesis and Targeted Therapy
Part of Annual Review Of Pathology, p. 321-344, ANNUAL REVIEWS, 2015
Conference papers
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Electron tomography analysis of Islet Amyloid Poly-Peptide aggregates in drosophila melanogaster
2017
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2014
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Part of Electron tomography, 2014