Dag Leonard

B cell polygenic risk scores associate with anti-dsDNA antibodies and nephritis in systemic lupus erythematosus

Hedenstedt, Anna; Reid, Sarah; Sayadi, Ahmed; Eloranta, Maija-Leena et al.

Part of Lupus Science and Medicine, 2023

• DOI for B cell polygenic risk scores associate with anti-dsDNA antibodies and nephritis in systemic lupus erythematosus
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Interaction between the STAT4rs11889341(T) risk allele and smoking confers increased risk of myocardial infarction and nephritis in patients with systemic lupus erythematosus

Reid, Sarah; Hagberg, Niklas; Sandling, Johanna K.; Alexsson, Andrei et al.

Part of Annals of the Rheumatic Diseases, p. 1183-1189, 2021

• DOI for Interaction between the STAT4rs11889341(T) risk allele and smoking confers increased risk of myocardial infarction and nephritis in patients with systemic lupus erythematosus
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High genetic risk score is associated with early disease onset, damage accrual and decreased survival in systemic lupus erythematosus

Reid, Sarah; Alexsson, Andrei; Frodlund, Martina; Morris, David et al.

Part of Annals of the Rheumatic Diseases, p. 363-369, 2020

• DOI for High genetic risk score is associated with early disease onset, damage accrual and decreased survival in systemic lupus erythematosus
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Interferon pathway in SLE: one key to unlocking the mystery of the disease

Rönnblom, Lars; Leonard, Dag

Part of Lupus Science and Medicine, 2019

• DOI for Interferon pathway in SLE: one key to unlocking the mystery of the disease
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Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis

Leonard, Dag; Svenungsson, Elisabet; Dahlqvist, Johanna; Alexsson, Andrei et al.

Part of Annals of the Rheumatic Diseases, p. 1063-1069, 2018

• DOI for Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis
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Activated T cells enhance interferon-α production by plasmacytoid dendritic cells stimulated with RNA-containing immune complexes

Leonard, Dag; Eloranta, Maija-Leena; Hagberg, Niklas; Berggren, Olof et al.

Part of Annals of the Rheumatic Diseases, p. 1728-1734, 2016

• DOI for Activated T cells enhance interferon-α production by plasmacytoid dendritic cells stimulated with RNA-containing immune complexes

Genetic and epigenetic determinants of relapse risk in lupus nephritis

Skoglund, Elisabeth; Skoglund, Oliver; Vestin, Holme; Oparina, Nina et al.

Part of Lupus Science and Medicine, 2026

• DOI for Genetic and epigenetic determinants of relapse risk in lupus nephritis
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Lectin pathway of complement in SLE: MAP-1 as a marker of haematological manifestations and elevated type I interferon activity

Lindelöf, Linnea; Garred, Peter; Hong, Mun-Gwan; Wahl Vaelum, Sasha et al.

Part of Lupus Science and Medicine, 2026

• DOI for Lectin pathway of complement in SLE: MAP-1 as a marker of haematological manifestations and elevated type I interferon activity
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Comparison of BAFF and type I IFN activity in blood and placenta in SLE and healthy pregnancies

Torell, Agnes; Andersson, Kerstin; Gunnarsson, Iva; Svenungsson, Elisabet et al.

Part of Lupus Science and Medicine, 2026

• DOI for Comparison of BAFF and type I IFN activity in blood and placenta in SLE and healthy pregnancies
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Single-cell RNA-seq reveals a persistent interferon signature in immune cells from systemic lupus erythematosus patients with high versus low polygenic risk scores despite antimalarial treatment

Sayadi, Ahmed; Eloranta, Maija-Leena; Oparina, Nina Y.; Wallgren, Marcus et al.

Part of Journal of Autoimmunity, 2026

• DOI for Single-cell RNA-seq reveals a persistent interferon signature in immune cells from systemic lupus erythematosus patients with high versus low polygenic risk scores despite antimalarial treatment
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Genetic risk factors and clinical manifestations of systemic lupus erythematosus: Large‐scale analysis of genetic predisposition and disease subtypes

Reid, Sarah; Sandling, Johanna K.; Pucholt, Pascal; Sayadi, Ahmed et al.

Part of Journal of Internal Medicine, p. 95-108, 2026

• DOI for Genetic risk factors and clinical manifestations of systemic lupus erythematosus: Large‐scale analysis of genetic predisposition and disease subtypes
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Genetic and epigenetic determinants of relapse risk in lupus nephritis

Skoglund, Elisabeth; Skoglund, Oliver; Vestin, Holme; Oparina, Nina et al.

Part of Lupus Science and Medicine, 2026

• DOI for Genetic and epigenetic determinants of relapse risk in lupus nephritis
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Lectin pathway of complement in SLE: MAP-1 as a marker of haematological manifestations and elevated type I interferon activity

Lindelöf, Linnea; Garred, Peter; Hong, Mun-Gwan; Wahl Vaelum, Sasha et al.

Part of Lupus Science and Medicine, 2026

• DOI for Lectin pathway of complement in SLE: MAP-1 as a marker of haematological manifestations and elevated type I interferon activity
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Comparison of BAFF and type I IFN activity in blood and placenta in SLE and healthy pregnancies

Torell, Agnes; Andersson, Kerstin; Gunnarsson, Iva; Svenungsson, Elisabet et al.

Part of Lupus Science and Medicine, 2026

• DOI for Comparison of BAFF and type I IFN activity in blood and placenta in SLE and healthy pregnancies
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Single-cell RNA-seq reveals a persistent interferon signature in immune cells from systemic lupus erythematosus patients with high versus low polygenic risk scores despite antimalarial treatment

Sayadi, Ahmed; Eloranta, Maija-Leena; Oparina, Nina Y.; Wallgren, Marcus et al.

Part of Journal of Autoimmunity, 2026

• DOI for Single-cell RNA-seq reveals a persistent interferon signature in immune cells from systemic lupus erythematosus patients with high versus low polygenic risk scores despite antimalarial treatment
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Genetic risk factors and clinical manifestations of systemic lupus erythematosus: Large‐scale analysis of genetic predisposition and disease subtypes

Reid, Sarah; Sandling, Johanna K.; Pucholt, Pascal; Sayadi, Ahmed et al.

Part of Journal of Internal Medicine, p. 95-108, 2026

• DOI for Genetic risk factors and clinical manifestations of systemic lupus erythematosus: Large‐scale analysis of genetic predisposition and disease subtypes
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Autoantibody-defined subsets of patients with systemic lupus erythematosus associate with clinical manifestations, NCF2, and HLA DR3-DQ2 genotypes

Leffers, Henrik Christian Bidstrup; Troldborg, Anne; Andersen, Martin; Sanchez, Ana Cristina Gonzalez et al.

Part of Translational Research, p. 29-37, 2025

• DOI for Autoantibody-defined subsets of patients with systemic lupus erythematosus associate with clinical manifestations, NCF2, and HLA DR3-DQ2 genotypes
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Patients with systemic lupus erythematosus (SLE) have an increased bisphenol A methylation score linked to SLE risk genes and selected clinical subphenotypes

Vestin, Holme; Oparina, Nina Y.; Eloranta, Maija-Leena; Frodlund, Martina et al.

Part of RMD Open, 2025

• DOI for Patients with systemic lupus erythematosus (SLE) have an increased bisphenol A methylation score linked to SLE risk genes and selected clinical subphenotypes
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Proteomic analysis reveals angiogenesis-related plasma proteins associated with pre-eclampsia in SLE

Torell, Agnes; Andersson, Kerstin; Gunnarsson, Iva; Svenungsson, Elisabet et al.

Part of Lupus Science and Medicine, 2025

• DOI for Proteomic analysis reveals angiogenesis-related plasma proteins associated with pre-eclampsia in SLE
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High-intensity interval training outperforms moderate exercise to improve aerobic capacity in patients with recent-onset idiopathic inflammatory myopathies: a multicentre randomised controlled trial

Andreasson, Kristofer M.; Leijding, Cecilia; Dastmalchi, Maryam; Notarnicola, Antonella et al.

Part of eBioMedicine, 2025

• DOI for High-intensity interval training outperforms moderate exercise to improve aerobic capacity in patients with recent-onset idiopathic inflammatory myopathies: a multicentre randomised controlled trial
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Epidemiology of patients with moderate-to-severe SLE in Sweden

Frodlund, Martina; Leonard, Dag; Haugli-Stephens, Thomas; Remkus, Lauren et al.

Part of Lupus Science and Medicine, 2025

• DOI for Epidemiology of patients with moderate-to-severe SLE in Sweden
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A high polygenic risk score is associated with SSA/SSB antibody positivity and early onset in primary Sjögren’s disease

Fugmann, Cecilia; Reid, Sarah; Pucholt, Pascal; Kvarnström, Marika et al.

Part of Rheumatology, p. 4341-4346, 2025

• DOI for A high polygenic risk score is associated with SSA/SSB antibody positivity and early onset in primary Sjögren’s disease
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Optimism in inclusion body myositis: a double-blind randomised controlled phase III trial investigating the effect of sirolimus on disease progression in patients with IBM as measured by the IBM Functional Rating Scale

Badrising, U. A.; Henderson, R.; Reddel, S.; Corbett, A. et al.

Part of Clinical and Experimental Rheumatology, p. 316-325, 2025

• DOI for Optimism in inclusion body myositis: a double-blind randomised controlled phase III trial investigating the effect of sirolimus on disease progression in patients with IBM as measured by the IBM Functional Rating Scale

Unraveling the Genetics of Shared Clinical and Serological Manifestations in Patients With Systemic Inflammatory Autoimmune Diseases

Bianchi, Matteo; Kozyrev, Sergey V.; Notarnicola, Antonella; Sandling, Johanna K. et al.

Part of Arthritis & Rheumatology, p. 212-225, 2025

• DOI for Unraveling the Genetics of Shared Clinical and Serological Manifestations in Patients With Systemic Inflammatory Autoimmune Diseases
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A survey of ficolin-3 activity in Systemic Lupus Erythematosus reveals a link to hematological disease manifestations and autoantibody profile

Lindelöf, Linnea; Rantapää-Dahlqvist, Solbritt; Lundtoft, Christian; Sandling, Johanna K. et al.

Part of Journal of Autoimmunity, 2024

• DOI for A survey of ficolin-3 activity in Systemic Lupus Erythematosus reveals a link to hematological disease manifestations and autoantibody profile
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Plasma interferon-alpha protein levels during pregnancy are associated with lower birth weight in systemic lupus erythematosus

Stockfelt, Marit; Torell, Agnes; Gunnarsson, Iva; Svenungsson, Elisabet et al.

Part of Rheumatology, p. 1469-1475, 2024

• DOI for Plasma interferon-alpha protein levels during pregnancy are associated with lower birth weight in systemic lupus erythematosus
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Glucocorticoid treatment in SLE is associated with infections, comorbidities and mortality-a national cohort study

Frodlund, Martina; Jonsen, Andreas; Remkus, Lauren; Telg, Gunilla et al.

Part of Rheumatology, p. 1104-1112, 2024

• DOI for Glucocorticoid treatment in SLE is associated with infections, comorbidities and mortality-a national cohort study
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Low CD4+T cell count is related to specific anti-nuclear antibodies, IFNα protein positivity and disease activity in systemic lupus erythematosus pregnancy

Torell, Agnes; Stockfelt, Marit; Blennow, Kaj; Zetterberg, Henrik et al.

Part of Arthritis Research & Therapy, 2024

• DOI for Low CD4+T cell count is related to specific anti-nuclear antibodies, IFNα protein positivity and disease activity in systemic lupus erythematosus pregnancy
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Patient global assessment and inflammatory markers in patients with idiopathic inflammatory myopathies: A longitudinal study

Lodin, Karin; Espinosa-Ortega, Fabricio; Dastmalchi, Maryam; Vencovsky, Jiri et al.

Part of Seminars in Arthritis & Rheumatism, 2024

• DOI for Patient global assessment and inflammatory markers in patients with idiopathic inflammatory myopathies: A longitudinal study
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Low-density granulocytes are related to shorter pregnancy duration but not to interferon alpha protein blood levels in systemic lupus erythematosus

Torell, Agnes; Stockfelt, Marit; Larsson, Gunilla; Blennow, Kaj et al.

Part of Arthritis Research & Therapy, 2023

• DOI for Low-density granulocytes are related to shorter pregnancy duration but not to interferon alpha protein blood levels in systemic lupus erythematosus
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B cell polygenic risk scores associate with anti-dsDNA antibodies and nephritis in systemic lupus erythematosus

Hedenstedt, Anna; Reid, Sarah; Sayadi, Ahmed; Eloranta, Maija-Leena et al.

Part of Lupus Science and Medicine, 2023

• DOI for B cell polygenic risk scores associate with anti-dsDNA antibodies and nephritis in systemic lupus erythematosus
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Strong Association of Combined Genetic Deficiencies in the Classical Complement Pathway With Risk of Systemic Lupus Erythematosus and Primary Sjögren's Syndrome

Lundtoft, Christian; Sjöwall, Christopher; Rantapää‐Dahlqvist, Solbritt; Bengtsson, Anders A. et al.

Part of Arthritis & Rheumatology, p. 1842-1850, 2022

• DOI for Strong Association of Combined Genetic Deficiencies in the Classical Complement Pathway With Risk of Systemic Lupus Erythematosus and Primary Sjögren's Syndrome
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Four Systemic Lupus Erythematosus Subgroups, Defined by Autoantibodies Status, Differ Regarding HLA-DRB1 Genotype Associations and Immunological and Clinical Manifestations

Diaz-Gallo, Lina-Marcela; Oke, Vilija; Lundström, Emeli; Elvin, Kerstin et al.

Part of ACR Open Rheumatology, p. 27-39, 2022

• DOI for Four Systemic Lupus Erythematosus Subgroups, Defined by Autoantibodies Status, Differ Regarding HLA-DRB1 Genotype Associations and Immunological and Clinical Manifestations
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Complement C4 Copy Number Variation is Linked to SSA/Ro and SSB/La Autoantibodies in Systemic Inflammatory Autoimmune Diseases

Lundtoft, Christian; Pucholt, Pascal; Martin, Myriam; Bianchi, Matteo et al.

Part of Arthritis & Rheumatology, p. 1440-1450, 2022

• DOI for Complement C4 Copy Number Variation is Linked to SSA/Ro and SSB/La Autoantibodies in Systemic Inflammatory Autoimmune Diseases
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Mer-tyrosine kinase: a novel susceptibility gene for SLE related end-stage renal disease

Yavuz, Sule; Pucholt, Pascal; Sandling, Johanna K.; Bianchi, Matteo et al.

Part of Lupus Science and Medicine, 2022

• DOI for Mer-tyrosine kinase: a novel susceptibility gene for SLE related end-stage renal disease
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Toll-like receptors revisited: a possible role for TLR1 in lupus nephritis

Yavuz, Sule; Bianchi, Matteo; Kozyrev, Sergey; Bolin, Karin et al.

Part of Annals of the Rheumatic Diseases, p. 404-406, 2021

• DOI for Toll-like receptors revisited: a possible role for TLR1 in lupus nephritis
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Contributions of de novo variants to systemic lupus erythematosus

Carlsson Almlöf, Jonas; Nystedt, Sara; Mechtidou, Aikaterini; Leonard, Dag et al.

Part of European Journal of Human Genetics, p. 184-193, 2021

• DOI for Contributions of de novo variants to systemic lupus erythematosus
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Molecular pathways in patients with systemic lupus erythematosus revealed by gene-centred DNA sequencing

Sandling, Johanna K.; Pucholt, Pascal; Hultin-Rosenberg, Lina; Farias, Fabiana H. G. et al.

Part of Annals of the Rheumatic Diseases, p. 109-117, 2021

• DOI for Molecular pathways in patients with systemic lupus erythematosus revealed by gene-centred DNA sequencing
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C-Reactive Protein Levels in Systemic Lupus Erythematosus Are Modulated by the Interferon Gene Signature and CRP Gene Polymorphism rs1205

Enocsson, Helena; Gullstrand, Birgitta; Eloranta, Maija-Leena; Wetterö, Jonas et al.

Part of Frontiers in Immunology, 2021

• DOI for C-Reactive Protein Levels in Systemic Lupus Erythematosus Are Modulated by the Interferon Gene Signature and CRP Gene Polymorphism rs1205
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Quick Systemic Lupus Activity Questionnaire (Q-SLAQ): a simplified version of SLAQ for patient-reported disease activity

Svenungsson, Elisabet; Gunnarsson, Iva; Illescas-Backelin, Vera; Trysberg, Estelle et al.

Part of Lupus Science and Medicine, 2021

• DOI for Quick Systemic Lupus Activity Questionnaire (Q-SLAQ): a simplified version of SLAQ for patient-reported disease activity
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Interaction between the STAT4rs11889341(T) risk allele and smoking confers increased risk of myocardial infarction and nephritis in patients with systemic lupus erythematosus

Reid, Sarah; Hagberg, Niklas; Sandling, Johanna K.; Alexsson, Andrei et al.

Part of Annals of the Rheumatic Diseases, p. 1183-1189, 2021

• DOI for Interaction between the STAT4rs11889341(T) risk allele and smoking confers increased risk of myocardial infarction and nephritis in patients with systemic lupus erythematosus
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Clinical Experience of Proteasome Inhibitor Bortezomib Regarding Efficacy and Safety in Severe Systemic Lupus Erythematosus: A Nationwide Study

Walhelm, Tomas; Gunnarsson, Iva; Heijke, Rebecca; Leonard, Dag et al.

Part of Frontiers in Immunology, 2021

• DOI for Clinical Experience of Proteasome Inhibitor Bortezomib Regarding Efficacy and Safety in Severe Systemic Lupus Erythematosus: A Nationwide Study
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De novo lupus nephritis during treatment with belimumab

Parodis, Ioannis; Vital, Edward M.; Hassan, Sabih-Ul; Jönsen, Andreas et al.

Part of Rheumatology, p. 4348-4354, 2021

• DOI for De novo lupus nephritis during treatment with belimumab
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Variants in BANK1 are associated with lupus nephritis of European ancestry.

Bolin, Karin; Imgenberg-Kreuz, Juliana; Leonard, Dag; Sandling, Johanna K. et al.

Part of Genes and Immunity, p. 194-202, 2021

• DOI for Variants in BANK1 are associated with lupus nephritis of European ancestry.
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Lymphopenia as a risk factor for neurologic involvement and organ damage accrual in patients with systemic lupus erythematosus: A multi-center observational study

Yavuz, Sule; Cansu, Dondu U.; Nikolopoulos, Dionysis; Crisafulli, Francesca et al.

Part of Seminars in Arthritis & Rheumatism, p. 1387-1393, 2020

• DOI for Lymphopenia as a risk factor for neurologic involvement and organ damage accrual in patients with systemic lupus erythematosus: A multi-center observational study

High genetic risk score is associated with early disease onset, damage accrual and decreased survival in systemic lupus erythematosus

Reid, Sarah; Alexsson, Andrei; Frodlund, Martina; Morris, David et al.

Part of Annals of the Rheumatic Diseases, p. 363-369, 2020

• DOI for High genetic risk score is associated with early disease onset, damage accrual and decreased survival in systemic lupus erythematosus
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NCF1-339 polymorphism is associated with altered formation of neutrophil extracellular traps, high serum interferon activity and antiphospholipid syndrome in systemic lupus erythematosus

Linge, Petrus; Arve, Sabine; Olsson, Lina M.; Leonard, Dag et al.

Part of Annals of the Rheumatic Diseases, p. 254-261, 2020

• DOI for NCF1-339 polymorphism is associated with altered formation of neutrophil extracellular traps, high serum interferon activity and antiphospholipid syndrome in systemic lupus erythematosus

Sex differences in clinical presentation of systemic lupus erythematosus

Ramírez Sepúlveda, Jorge I; Bolin, Karin; Mofors, Johannes; Leonard, Dag et al.

Part of Biology of Sex Differences, 2019

• DOI for Sex differences in clinical presentation of systemic lupus erythematosus
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The majority of Swedish systemic lupus erythematosus patients are still affected by irreversible organ impairment: factors related to damage accrual in two regional cohorts

Frodlund, M.; Reid, Sarah; Wettero, J.; Dahlstrom, O. et al.

Part of Lupus, p. 1261-1272, 2019

• DOI for The majority of Swedish systemic lupus erythematosus patients are still affected by irreversible organ impairment: factors related to damage accrual in two regional cohorts
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Autoantibodies to Killer Cell Immunoglobulin-Like Receptors in Patients With Systemic Lupus Erythematosus Induce Natural Killer Cell Hyporesponsiveness

Segerberg, Filip; Lundtoft, Christian; Reid, Sarah; Hjorton, Karin et al.

Part of Frontiers in Immunology, 2019

• DOI for Autoantibodies to Killer Cell Immunoglobulin-Like Receptors in Patients With Systemic Lupus Erythematosus Induce Natural Killer Cell Hyporesponsiveness
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Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus

Odqvist, Lina; Jevnikar, Zala; Riise, Rebecca; Oberg, Lisa et al.

Part of Annals of the Rheumatic Diseases, p. 1363-1370, 2019

• DOI for Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus
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Shared and Unique Patterns of DNA Methylation in Systemic Lupus Erythematosus and Primary Sjogren's Syndrome

Imgenberg-Kreuz, Juliana; Carlsson Almlöf, Jonas; Leonard, Dag; Sjöwall, Christopher et al.

Part of Frontiers in Immunology, 2019

• DOI for Shared and Unique Patterns of DNA Methylation in Systemic Lupus Erythematosus and Primary Sjogren's Syndrome
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Whole-genome sequencing identifies complex contributions to genetic risk by variants in genes causing monogenic systemic lupus erythematosus

Almlöf, Jonas Carlsson; Nystedt, Sara; Leonard, Dag; Eloranta, Maija-Leena et al.

Part of Human Genetics, p. 141-150, 2019

• DOI for Whole-genome sequencing identifies complex contributions to genetic risk by variants in genes causing monogenic systemic lupus erythematosus
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A rare regulatory variant in the MEF2D gene affects gene regulation and splicing and is associated with a SLE sub-phenotype in Swedish cohorts

Farias, Fabiana H. G.; Dahlqvist, Johanna; Kozyrev, Sergey V.; Leonard, Dag et al.

Part of European Journal of Human Genetics, p. 432-441, 2019

• DOI for A rare regulatory variant in the MEF2D gene affects gene regulation and splicing and is associated with a SLE sub-phenotype in Swedish cohorts
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Shared and unique patterns of DNA methylation in primary Sjogren's syndrome and systemic lupus erythematosus

Imgenberg-Kreuz, Juliana; Leonard, Dag; Carlsson Almlöf, Jonas; Rantapaa-Dahlqvist, S. et al.

Part of Scandinavian Journal of Rheumatology, p. 3-3, 2018

The STAT4 SLE risk allele rs7574865[T] is associated with increased IL-12-induced IFN-γ production in T cells from patients with SLE

Hagberg, Niklas; Joelsson, Martin; Leonard, Dag; Reid, Sarah et al.

Part of Annals of the Rheumatic Diseases, p. 1070-1077, 2018

• DOI for The STAT4 SLE risk allele rs7574865[T] is associated with increased IL-12-induced IFN-γ production in T cells from patients with SLE
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Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis

Leonard, Dag; Svenungsson, Elisabet; Dahlqvist, Johanna; Alexsson, Andrei et al.

Part of Annals of the Rheumatic Diseases, p. 1063-1069, 2018

• DOI for Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis
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DNA methylation mapping identifies gene regulatory effects in patients with systemic lupus erythematosus

Imgenberg-Kreuz, Juliana; Almlöf, Jonas Carlsson; Leonard, Dag; Alexsson, Andrei et al.

Part of Annals of the Rheumatic Diseases, p. 736-743, 2018

• DOI for DNA methylation mapping identifies gene regulatory effects in patients with systemic lupus erythematosus
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The risk allele A of rs200395694 associated with SLE in Swedish patients affects on MEF2D gene regulation and alternative splicing

Abramov, Sergei; Kozyrev, Sergey V.; Farias, Fabiana H. G.; Dahlqvist, Johanna et al.

Part of Human Gene Therapy, 2018

ILF2 and ILF3 are autoantigens in canine systemic autoimmune disease

Bremer, Hanna D.; Landegren, Nils; Sjöberg, Ronald; Hallgren, Åsa et al.

Part of Scientific Reports, 2018

• DOI for ILF2 and ILF3 are autoantigens in canine systemic autoimmune disease
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Treatment-Associated DNA Methylation Patterns in Systemic Lupus Erythematosus

Imgenberg-Kreuz, Juliana; Almlöf, Jonas Carlsson; Leonard, Dag; Nordmark, Gunnel et al.

Part of Arthritis & Rheumatology, 2017

SLE Comprises Four Immune-Phenotypes, Which Differ Regarding HLA-DRB1 and Clinical Associations

Gallo, Lina Marcela Diaz; Lundstrom, Emeli; Oke, Vilija; Elvin, Kerstin et al.

Part of Arthritis & Rheumatology, 2017

High Genetic Risk Score Is Associated with Increased Organ Damage in SLE

Reid, Sarah; Alexsson, Andrei; Frodlund, Martina; Sandling, Johanna K. et al.

Part of Arthritis & Rheumatology, 2017

Novel risk genes for systemic lupus erythematosus predicted by random forest classification

Carlsson Almlöf, Jonas; Alexsson, Andrei; Imgenberg-Kreuz, Juliana; Sylwan, Lina et al.

Part of Scientific Reports, 2017

• DOI for Novel risk genes for systemic lupus erythematosus predicted by random forest classification
• Download full text (pdf) of Novel risk genes for systemic lupus erythematosus predicted by random forest classification

A single nucleotide polymorphism in the NCF1 gene leading to reduced oxidative burst is associated with systemic lupus erythematosus

Olsson, Lina M.; Johansson, Asa C.; Gullstrand, Birgitta; Jonsen, Andreas et al.

Part of Annals of the Rheumatic Diseases, p. 1607-1613, 2017

• DOI for A single nucleotide polymorphism in the NCF1 gene leading to reduced oxidative burst is associated with systemic lupus erythematosus

Activated T cells enhance interferon-α production by plasmacytoid dendritic cells stimulated with RNA-containing immune complexes

Leonard, Dag; Eloranta, Maija-Leena; Hagberg, Niklas; Berggren, Olof et al.

Part of Annals of the Rheumatic Diseases, p. 1728-1734, 2016

• DOI for Activated T cells enhance interferon-α production by plasmacytoid dendritic cells stimulated with RNA-containing immune complexes

Early B Cell Factor 1 is Associated to Clinical Manifestations in Primary Sjogren's Syndrome and SLE

Bolin, Karin; Leonard, Dag; Gunnarsson, I.; Sjowall, C. et al.

Part of Scandinavian Journal of Immunology, p. 416-416, 2015

Activated SLE-T Cells Enhance the Interferon-Alpha Production By Plasmacytoid Dendritic Cells Stimulated By RNA-IC

Leonard, Dag; Eloranta, Maija-Leena; Hagberg, Niklas; Berggren, Olof et al.

Part of Arthritis & Rheumatology, 2014

High-Throughput Sequencing of 219 Candidate Genes for Identification of SLE-Associated Risk Variants

Farias, Fabiana; Wilbe, Maria; Dahlqvist, Johanna; Leonard, Dag et al.

Part of Arthritis & Rheumatology, 2014

Activated T cells enhance interferon-alpha production by plasmacytoid dendritic cells stimulated by RNA-containing immune complexes

Leonard, Dag; Eloranta, Maija-Leena; Hagberg, Niklas; Berggren, Olof et al.

Part of Scandinavian Journal of Rheumatology, p. 88-89, 2014

Clinical manifestations and anti-phospholipid antibodies in 712 patients with systemic lupus erythematosus: evaluation of two diagnostic assays

Vikerfors, Anna; Johansson, Anna-Britta; Gustafsson, Johanna T; Jönsen, Andreas et al.

Part of Rheumatology, p. 345-353, 2013

• DOI for Clinical manifestations and anti-phospholipid antibodies in 712 patients with systemic lupus erythematosus: evaluation of two diagnostic assays

HLA-DRB1*04/*13 alleles are associated with vascular disease and antiphospholipid antibodies in systemic lupus erythematosus

Lundström, Emeli; Gustafsson, Johanna T; Jönsen, Andreas; Leonard, Dag et al.

Part of Annals of the Rheumatic Diseases, p. 1018-1025, 2013

• DOI for HLA-DRB1*04/*13 alleles are associated with vascular disease and antiphospholipid antibodies in systemic lupus erythematosus

Direct and Indirect Costs For Patients With Systemic Lupus Erythematosus In National Cohorts In Sweden

Jonsen, Andreas; Bengtsson, Anders A.; Bengtsson, Christine; Gunnarsson, Iva et al.

Part of Arthritis and Rheumatism, 2013

Coronary heart disease in systemic lupus erythematosus is associated with interferon regulatory factor-8 gene variants

Leonard, Dag; Svenungsson, Elisabet; Sandling, Johanna K; Berggren, Olof et al.

Part of Circulation, p. 255-263, 2013

• DOI for Coronary heart disease in systemic lupus erythematosus is associated with interferon regulatory factor-8 gene variants

Coronary Heart Disease in Systemic Lupus Erythematosus is Associated with Interferon Regulatory Factor 8 Gene Variants

Leonard, Dag; Svenungsson, E.; Sandling, J. K.; Berggren, Olof et al.

Part of Annals of the Rheumatic Diseases, p. 270-270, 2013

• DOI for Coronary Heart Disease in Systemic Lupus Erythematosus is Associated with Interferon Regulatory Factor 8 Gene Variants

Ischemic vascular disease and antiphospholipid antibodies are associated with HLA-DRB1 *04/*13 alleles in systemic lupus erythematosus

Svenungsson, Elisabet; Lundström, Emeli; Gustafsson, Johanna; Jonsen, Andreas et al.

Part of Annals of the Rheumatic Diseases, 2012

• DOI for Ischemic vascular disease and antiphospholipid antibodies are associated with HLA-DRB1 *04/*13 alleles in systemic lupus erythematosus

Increased carotid intima thickness and decreased media thickness in premenopausal women with systemic lupus erythematosus: an investigation by non-invasive high-frequency ultrasound

Leonard, Dag; Akhter, Tansim; Nordmark, Gunnel; Rönnblom, Lars et al.

Part of Scandinavian Journal of Rheumatology, p. 279-282, 2011

• DOI for Increased carotid intima thickness and decreased media thickness in premenopausal women with systemic lupus erythematosus: an investigation by non-invasive high-frequency ultrasound

IFN-α Production by Plasmacytoid Dendritic Cells Stimulated with RNA-Containing Immune Complexes Is Promoted by NK Cells via MIP-1β and LFA-1

Hagberg, Niklas; Berggren, Olof; Leonard, Dag; Weber, Gert et al.

Part of Journal of Immunology, p. 5085-5094, 2011

• DOI for IFN-α Production by Plasmacytoid Dendritic Cells Stimulated with RNA-Containing Immune Complexes Is Promoted by NK Cells via MIP-1β and LFA-1

A STAT4 risk allele is associated with ischaemic cerebrovascular events and anti-phospholipid antibodies in systemic lupus erythematosus

Svenungsson, Elisabet; Gustafsson, Johanna; Leonard, Dag; Sandling, Johanna et al.

Part of Annals of the Rheumatic Diseases, p. 834-840, 2010

• DOI for A STAT4 risk allele is associated with ischaemic cerebrovascular events and anti-phospholipid antibodies in systemic lupus erythematosus

Interferon pathway in SLE: one key to unlocking the mystery of the disease

Rönnblom, Lars; Leonard, Dag

Part of Lupus Science and Medicine, 2019

• DOI for Interferon pathway in SLE: one key to unlocking the mystery of the disease
• Download full text (pdf) of Interferon pathway in SLE: one key to unlocking the mystery of the disease

Direct and indirect costs for systemic lupus erythematosus in Sweden. A nationwide health economic study based on five defined cohorts

Jönsen, Andreas; Hjalte, Frida; Willim, Minna; Carlsson, Katarina Steen et al.

Part of Seminars in Arthritis & Rheumatism, p. 684-690, 2016

• DOI for Direct and indirect costs for systemic lupus erythematosus in Sweden. A nationwide health economic study based on five defined cohorts

Cardiovascular Disease and Immune Mechanisms in Systemic Lupus Erythematosus

Leonard, Dag

2014

• Download full text (pdf) of Cardiovascular Disease and Immune Mechanisms in Systemic Lupus Erythematosus

Variants in BANK1 are associated with lupus nephritis

Bolin, Karin; Leonard, Dag; Sandling, Johanna K.; Imgenberg-Kreuz, Juliana et al.

From genetic predisposition to clinical outcome in systemic lupus erythematosus: construction and validation of sub-phenotype-specific genetic risk scores

Reid, Sarah; Sandling, Johanna K.; Pucholt, Pascal; Sayadi, Ahmed et al.

Activated T cells enhance interferon-alpha production by plasmacytoid dendritic cells stimulated by RNA-containing immune complexes

Leonard, Dag; Eloranta, Maija-Leena; Hagberg, Niklas; Berggren, Olof et al.

The Lectin Pathway of Complement in Systemic Lupus Erythematosus: MAP-1 as a Marker of Hematological Manifestations and Elevated Type I Interferon Activity

Lindelöf, Linnea; Garred, Peter; Hong, Mun-Gwan; Wahl Vælum, Sasha et al.