Evelina Vågesjö

In Vitro Elimination of Highly Multidrug-Resistant Bacteria by the Lactic Acid Bacterial Drug Candidate ILP100

Lofton Tomenius, Hava; Pang, Yanhong; Pallin, Anton; Myktybekova, Zhanar et al.

Part of Infectious Diseases and Therapy, p. 1119-1131, 2025

• DOI for In Vitro Elimination of Highly Multidrug-Resistant Bacteria by the Lactic Acid Bacterial Drug Candidate ILP100
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Corpora cavernosa fibroblasts mediate penile erection

Linck Guimaraes, Eduardo; Oliveira Dias, David; Hau, Wing Fung; Julien, Anais et al.

Part of Science, 2024

• DOI for Corpora cavernosa fibroblasts mediate penile erection

Oral administration of CXCL12-expressing Limosilactobacillus reuteri improves colitis by local immunomodulatory actions in preclinical models

Öhnstedt, Emelie; Doñas, Cristian; Parv, Kristel; Pang, Yanhong et al.

Part of American Journal of Physiology - Gastrointestinal and Liver Physiology, 2024

• DOI for Oral administration of CXCL12-expressing Limosilactobacillus reuteri improves colitis by local immunomodulatory actions in preclinical models
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Engineered bacteria to accelerate wound healing: an adaptive, randomised, double-blind, placebo-controlled, first-in-human phase 1 trial

Öhnstedt, Emelie; Vågesjö, Evelina; Fasth, Andreas; Tomenius, Hava Lofton et al.

Part of eClinicalMedicine, 2023

• DOI for Engineered bacteria to accelerate wound healing: an adaptive, randomised, double-blind, placebo-controlled, first-in-human phase 1 trial
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Accelerated Wound Healing in Minipigs by On-Site Production and Delivery of CXCL12 by Transformed Lactic Acid Bacteria

Öhnstedt, Emelie; Lofton Tomenius, Hava; Frank, Peter; Roos, Stefan et al.

Part of Pharmaceutics, 2022

• DOI for Accelerated Wound Healing in Minipigs by On-Site Production and Delivery of CXCL12 by Transformed Lactic Acid Bacteria
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In Vitro Elimination of Highly Multidrug-Resistant Bacteria by the Lactic Acid Bacterial Drug Candidate ILP100

Lofton Tomenius, Hava; Pang, Yanhong; Pallin, Anton; Myktybekova, Zhanar et al.

Part of Infectious Diseases and Therapy, p. 1119-1131, 2025

• DOI for In Vitro Elimination of Highly Multidrug-Resistant Bacteria by the Lactic Acid Bacterial Drug Candidate ILP100
• Download full text (pdf) of In Vitro Elimination of Highly Multidrug-Resistant Bacteria by the Lactic Acid Bacterial Drug Candidate ILP100

Corpora cavernosa fibroblasts mediate penile erection

Linck Guimaraes, Eduardo; Oliveira Dias, David; Hau, Wing Fung; Julien, Anais et al.

Part of Science, 2024

• DOI for Corpora cavernosa fibroblasts mediate penile erection

Oral administration of CXCL12-expressing Limosilactobacillus reuteri improves colitis by local immunomodulatory actions in preclinical models

Öhnstedt, Emelie; Doñas, Cristian; Parv, Kristel; Pang, Yanhong et al.

Part of American Journal of Physiology - Gastrointestinal and Liver Physiology, 2024

• DOI for Oral administration of CXCL12-expressing Limosilactobacillus reuteri improves colitis by local immunomodulatory actions in preclinical models
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Engineered bacteria to accelerate wound healing: an adaptive, randomised, double-blind, placebo-controlled, first-in-human phase 1 trial

Öhnstedt, Emelie; Vågesjö, Evelina; Fasth, Andreas; Tomenius, Hava Lofton et al.

Part of eClinicalMedicine, 2023

• DOI for Engineered bacteria to accelerate wound healing: an adaptive, randomised, double-blind, placebo-controlled, first-in-human phase 1 trial
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Accelerated Wound Healing in Minipigs by On-Site Production and Delivery of CXCL12 by Transformed Lactic Acid Bacteria

Öhnstedt, Emelie; Lofton Tomenius, Hava; Frank, Peter; Roos, Stefan et al.

Part of Pharmaceutics, 2022

• DOI for Accelerated Wound Healing in Minipigs by On-Site Production and Delivery of CXCL12 by Transformed Lactic Acid Bacteria
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How can we optimize the development of drugs for wound healing?

Vågesjö, Evelina; Grigoleit, Patricia; Fasth, Andreas; Phillipson, Mia

Part of Expert Opinion on Drug Discovery, p. 93-96, 2022

• DOI for How can we optimize the development of drugs for wound healing?

Perivascular macrophages regulate blood flow following tissue damage

Vågesjö, Evelina; Parv, Kristel; Ahl, David; Seignez, Cedric et al.

Part of Circulation Research, p. 1694-1707, 2021

• DOI for Perivascular macrophages regulate blood flow following tissue damage

Accelerated wound healing in mice by on-site production and delivery of CXCL12 by transformed lactic acid bacteria

Vågesjö, Evelina; Öhnstedt, Emelie; Mortier, Anneleen; Lofton, Hava et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 1895-1900, 2018

• DOI for Accelerated wound healing in mice by on-site production and delivery of CXCL12 by transformed lactic acid bacteria
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Effect of neonatal infections on pancreatic macrophages, islet development and long-term glucose homeostasis

Herrera Hidalgo, Carmen; Ullsten, Sara; Vågesjö, Evelina; Parv, Kristel et al.

Part of European Journal of Clinical Investigation, p. 83-83, 2018

• DOI for Effect of neonatal infections on pancreatic macrophages, islet development and long-term glucose homeostasis

Perivascular macrophages regulate blood flow following tissue damage

Vågesjö, Evelina; Seignez, Cedric; Christoffersson, Gustaf; Herrera Hidalgo, Carmen et al.

Part of European Journal of Clinical Investigation, p. 44-45, 2018

• DOI for Perivascular macrophages regulate blood flow following tissue damage

A novel drug-delivery system and drug candidate: using probiotic bacteria as bioreactors for delivery of therapeutic chemokines in wound healing

Lofton Tomenius, Hava; Vågesjö, Evelina; Öhnstedt, E.; Mortier, A. et al.

Part of European Journal of Clinical Investigation, p. 79-79, 2018

• DOI for A novel drug-delivery system and drug candidate: using probiotic bacteria as bioreactors for delivery of therapeutic chemokines in wound healing

Bioengineering of the local wound environment accelerates wound healing by increasing macrophage density and induces a phenotype shift in the wound macrophages

Öhnstedt, E.; Vågesjö, Evelina; Lofton Tomenius, Hava; Roos, S. et al.

Part of European Journal of Clinical Investigation, p. 79-79, 2018

• DOI for Bioengineering of the local wound environment accelerates wound healing by increasing macrophage density and induces a phenotype shift in the wound macrophages

In Vivo and In Vitro Detection of Luminescent and Fluorescent Lactobacillus reuteri and Application of Red Fluorescent mCherry for Assessing Plasmid Persistence

Karimi, Shokoufeh; Ahl, David; Vagesjö, Evelina; Holm, Lena et al.

Part of PLOS ONE, 2016

• DOI for In Vivo and In Vitro Detection of Luminescent and Fluorescent Lactobacillus reuteri and Application of Red Fluorescent mCherry for Assessing Plasmid Persistence
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Identification and characterization of VEGF-A-responsive neutrophils expressing CD49d, VEGFR1, and CXCR4 in mice and humans

Massena, Sara; Christoffersson, Gustaf; Vågesjö, Evelina; Seignez, Cédric et al.

Part of Blood, p. 2016-2026, 2015

• DOI for Identification and characterization of VEGF-A-responsive neutrophils expressing CD49d, VEGFR1, and CXCR4 in mice and humans

Shb deficiency in endothelium but not in leukocytes is responsible for impaired vascular performance during hindlimb ischemia.

Nikpour, Maryam; Gustafsson, Karin; Vågesjö, Evelina; Seignez, Cedric et al.

Part of Acta Physiologica, p. 200-209, 2015

• DOI for Shb deficiency in endothelium but not in leukocytes is responsible for impaired vascular performance during hindlimb ischemia.
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Immunological Shielding by Induced Recruitment of Regulatory T-Lymphocytes Delays Rejection of Islets Transplanted in Muscle

Vågesjö, Evelina; Christoffersson, Gustaf; Waldén, Tomas B; Carlsson, Per-Ola et al.

Part of Cell Transplantation, p. 263-276, 2015

• DOI for Immunological Shielding by Induced Recruitment of Regulatory T-Lymphocytes Delays Rejection of Islets Transplanted in Muscle

Immunological shielding by induced recruitment of regulatory T lymphocytes delays rejection of islets transplanted to muscle

Vågesjö, Evelina; Christoffersson, Gustaf; Waldén, Tomas B; Carlsson, Per-Ola et al.

Part of Cell Transplantation, p. 263-276, 2015

• DOI for Immunological shielding by induced recruitment of regulatory T lymphocytes delays rejection of islets transplanted to muscle

Strategical steering of the immune system: induction of leukocyte vascular chaperoning increases functional blood flow responses in ischemic muscle

Vågesjö, Evelina; Christoffersson, Gustaf; Korsgren, Olle; Essand, Magnus et al.

Part of The FASEB Journal, 2014

Acute sleep deprivation in healthy young men: Impact on population diversity and function of circulating neutrophils

Christoffersson, Gustaf; Vågesjö, Evelina; Pettersson, Ulrika S.; Massena, Sara et al.

Part of Brain, behavior, and immunity, p. 162-172, 2014

• DOI for Acute sleep deprivation in healthy young men: Impact on population diversity and function of circulating neutrophils

Acute sleep deprivation increases serum levels of neuron-specific enolase (NSE) and S100 calcium binding protein B (S-100B) in healthy young men

Benedict, Christian; Cedernaes, Jonathan; Giedraitis, Vilmantas; Nilsson, Emil K et al.

Part of Sleep, p. 195-198, 2014

• DOI for Acute sleep deprivation increases serum levels of neuron-specific enolase (NSE) and S100 calcium binding protein B (S-100B) in healthy young men

Aberrant association between vascular endothelial growth factor receptor-2 and VE-cadherin in response to vascular endothelial growth factor-a in Shb-deficient lung endothelial cells

Zang, Guangxiang; Christoffersson, Gustaf; Tian, Geng; Harun-Or-Rashid, Mohammad et al.

Part of Cellular Signalling, p. 85-92, 2013

• DOI for Aberrant association between vascular endothelial growth factor receptor-2 and VE-cadherin in response to vascular endothelial growth factor-a in Shb-deficient lung endothelial cells
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The mechanisms of VEGF-A-induced recruitment of pro-angiogenic neutrophils

Massena, Sara; Christoffersson, Gustaf; Vågesjö, Evelina; Gustafsson, Karin et al.

Part of European Journal of Clinical Investigation, p. 27-27, 2013

A distinct subset of proangiogenic CD11b(+)/Gr-1(+)/CXCR4(+)/MMP-9(hi) neutrophils are recruited by VEGF-A to transplanted hypoxic tissue

Christoffersson, Gustaf; Vågesjö, Evalina; Giraud, Antoine; Massena, Sara et al.

Part of European Journal of Clinical Investigation, p. 9-9, 2013

Strategic recruitment of proangiogenic leukocytes to the ischemic hindlimb increases functional tissue perfusion

Vågesjö, Evalina; Christoffersson, Gustaf; Korsgren, Olle; Essand, Magnus et al.

Part of European Journal of Clinical Investigation, p. 27-27, 2013

VEGF-A recruits a proangiogenic MMP-9-delivering neutrophil subset that induces angiogenesis in transplanted hypoxic tissue

Christoffersson, Gustaf; Vågesjö, Evelina; Vandooren, Jennifer; Liden, Majken et al.

Part of Blood, p. 4653-4662, 2012

• DOI for VEGF-A recruits a proangiogenic MMP-9-delivering neutrophil subset that induces angiogenesis in transplanted hypoxic tissue

Vascular adaptation to a dysfunctional endothelium as a consequence of Shb deficiency

Christoffersson, Gustav; Zang, Guangxiang; Zhuang, Zhen W.; Vågesjö, Evelina et al.

Part of Angiogenesis, p. 469-480, 2012

• DOI for Vascular adaptation to a dysfunctional endothelium as a consequence of Shb deficiency
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The discovery and development of topical medicines for wound healing

Öhnstedt, Emelie; Lofton Tomenius, Hava; Vågesjö, Evelina; Phillipson, Mia

Part of Expert Opinion on Drug Discovery, p. 485-497, 2019

• DOI for The discovery and development of topical medicines for wound healing
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Exploring immune cell functions and ways to make use of them

Vågesjö, Evelina

2016

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Uncovering a new role for immune cells: macrophages assist in regulation of blood flow in ischemic muscle

Vågesjö, Evelina; Seignez, Cedric; Christoffersson, Gustaf; Korsgren, Olle et al.