Lucia Lazorova

The interplay between compression mechanisms and compaction pressure in relation to the loss of tabletability of dry granulated particles

Tofiq, Maryam; Persson, Ann-Sofie; Lazorova, Lucia; Nordström, Josefina et al.

Part of Powder Technology, 2025

• DOI for The interplay between compression mechanisms and compaction pressure in relation to the loss of tabletability of dry granulated particles
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Considerations on the quantitative analysis of apparent amorphicity of milled lactose by Raman spectroscopy

Pazesh, Samaneh; Lazorova, Lucia; Berggren, Jonas; Alderborn, Göran et al.

Part of International Journal of Pharmaceutics, p. 488-504, 2016

• DOI for Considerations on the quantitative analysis of apparent amorphicity of milled lactose by Raman spectroscopy
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The degree of compression of spherical granular solids controls the evolution of microstructure and bond probability during compaction

Nordström, Josefina; Persson, Ann-Sofie; Lazorova, Lucia; Frenning, Göran et al.

Part of International Journal of Pharmaceutics, p. 3-12, 2013

• DOI for The degree of compression of spherical granular solids controls the evolution of microstructure and bond probability during compaction
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Combined in Vitro-in Vivo Approach To Assess the Hepatobiliary Disposition of a Novel Oral Thrombin Inhibitor

Matsson, Elin M.; Eriksson, Ulf G.; Palm, Johan E.; Artursson, Per et al.

Part of Molecular Pharmaceutics, p. 4252-4262, 2013

• DOI for Combined in Vitro-in Vivo Approach To Assess the Hepatobiliary Disposition of a Novel Oral Thrombin Inhibitor

mRNA expression of drug-transporting proteins along the human intestine and comparison with expression in Caco-2 cells

Englund, Gunilla; Rorsman, Fredrik; Rönnblom, Anders; Lazorova, Lucia et al.

2012

The interplay between compression mechanisms and compaction pressure in relation to the loss of tabletability of dry granulated particles

Tofiq, Maryam; Persson, Ann-Sofie; Lazorova, Lucia; Nordström, Josefina et al.

Part of Powder Technology, 2025

• DOI for The interplay between compression mechanisms and compaction pressure in relation to the loss of tabletability of dry granulated particles
• Download full text (pdf) of The interplay between compression mechanisms and compaction pressure in relation to the loss of tabletability of dry granulated particles

Considerations on the quantitative analysis of apparent amorphicity of milled lactose by Raman spectroscopy

Pazesh, Samaneh; Lazorova, Lucia; Berggren, Jonas; Alderborn, Göran et al.

Part of International Journal of Pharmaceutics, p. 488-504, 2016

• DOI for Considerations on the quantitative analysis of apparent amorphicity of milled lactose by Raman spectroscopy
• Download full text (pdf) of Considerations on the quantitative analysis of apparent amorphicity of milled lactose by Raman spectroscopy

The degree of compression of spherical granular solids controls the evolution of microstructure and bond probability during compaction

Nordström, Josefina; Persson, Ann-Sofie; Lazorova, Lucia; Frenning, Göran et al.

Part of International Journal of Pharmaceutics, p. 3-12, 2013

• DOI for The degree of compression of spherical granular solids controls the evolution of microstructure and bond probability during compaction
• Download full text (pdf) of The degree of compression of spherical granular solids controls the evolution of microstructure and bond probability during compaction

Combined in Vitro-in Vivo Approach To Assess the Hepatobiliary Disposition of a Novel Oral Thrombin Inhibitor

Matsson, Elin M.; Eriksson, Ulf G.; Palm, Johan E.; Artursson, Per et al.

Part of Molecular Pharmaceutics, p. 4252-4262, 2013

• DOI for Combined in Vitro-in Vivo Approach To Assess the Hepatobiliary Disposition of a Novel Oral Thrombin Inhibitor

Structural Features Determining the Intestinal Epithelial Permeability and Efflux of Novel HIV-1 Protease Inhibitors

Lazorova, Lucia; Hubatsch, Ina; Ekegren, Jenny K.; Gising, Johan et al.

Part of Journal of Pharmaceutical Sciences, p. 3763-3772, 2011

• DOI for Structural Features Determining the Intestinal Epithelial Permeability and Efflux of Novel HIV-1 Protease Inhibitors

Genotype-dependent effects of inhibitors of the organic cation transporter, OCT1: predictions of metformin interactions

Ahlin, Gustav; Chen, L; Lazorova, Lucia; Chen, Ying et al.

Part of The Pharmacogenomics Journal, p. 400-411, 2011

• DOI for Genotype-dependent effects of inhibitors of the organic cation transporter, OCT1: predictions of metformin interactions

CFTR and tight junctions in cultured bronchial epithelial cells

Nilsson, Harriet; Dragomir, Anca; Lazorova, Lucia; Johannesson, Marie et al.

Part of Experimental and molecular pathology (Print), p. 118-127, 2010

• DOI for CFTR and tight junctions in cultured bronchial epithelial cells

Paracellular porosity and pore size of the human intestinal epithelium in tissue and cell culture models

Linnankoski, Johanna; Mäkelä, Johanna; Palmgren, Joni; Mauriala, Timo et al.

Part of Journal of Pharmaceutical Sciences, p. 2166-2175, 2010

• DOI for Paracellular porosity and pore size of the human intestinal epithelium in tissue and cell culture models

Regional levels of drug transporters along the human intestinal tract: Co-expression of ABC and SLC transporters and comparison with Caco-2 cells

Englund, Gunilla; Rorsman, Fredrik; Rönnblom, Anders; Karlbom, Urban et al.

Part of European Journal of Pharmaceutical Sciences, p. 269-277, 2006

• DOI for Regional levels of drug transporters along the human intestinal tract: Co-expression of ABC and SLC transporters and comparison with Caco-2 cells

Caco-2 permeability of weakly basic drugs predicted with the Double-Sink PAMPA pK flux a method.

Avdeef, Alex; Artursson, Per; Neuhoff, Sibylle; Lazorova, Lucia et al.

Part of Eur J Pharm Sci, p. 333-49, 2005

Orally active antiviral tripeptide glycyl-prolyl-glycinamide is activated by CD26 (dipeptidyl peptidase IV) before transport across the intestinal epithelium.

Hubatsch, Ina; Lazorova, Lucia; Vahlne, Anders; Artursson, Per

Part of Antimicrob Agents Chemother, p. 1087-92, 2005

Ketobemidone is a substrate for cytochrome P4502C9 and 3A4, but not for P-glycoprotein.

Yasar, U; Annas, A; Svensson, J-O; Lazorova, L et al.

Part of Xenobiotica, p. 785-96, 2005

Exploring the quantitative relationship between the level of MDR1 transcript, protein and function using digoxin as a marker ofMDR1-dependent drug efflux activity.

Taipalensuu, J; Tavelin, S; Lazorova, L; Svensson, AC et al.

Part of Eur J Pharm Sci, p. 69, 2004

Absorption classification of oral drugs based on molecular surface properties

Bergström, Christel A. S.; Strafford, Melissa; Lazorova, Lucia; Avdeef, Alex et al.

Part of Journal of Medicinal Chemistry, p. 558-570, 2003

• DOI for Absorption classification of oral drugs based on molecular surface properties

A New Principle for Tight Junction Modulation Based on Occludin Peptides

Tavelin, Staffan; Hashimoto, Kei; Lazorova, Lucia; Malkinson, John et al.

Part of Molecular Pharmacology, p. 1530-1540, 2003

• DOI for A New Principle for Tight Junction Modulation Based on Occludin Peptides

Absorption classification of oral drugs based on molecular surface properties

Bergström, Christel A S; Strafford, M; Lazorova, Lucia; Avdeef, A et al.

Part of Journal of Medicinal Chemistry, p. 558-570, 2003

• DOI for Absorption classification of oral drugs based on molecular surface properties

A new principle for tight junction modulation based on occludin peptides

Tavelin, Staffan; Hashimoto, Kei; Malkinson, J; Lazorova, Lucia et al.

Part of Molecular Pharmacology, p. 1530-1540, 2003

• DOI for A new principle for tight junction modulation based on occludin peptides

Determination of transport in the Caco-2 cell assay of compounds varying in lipophilicity using LC-MS: enhanced transport of Leu-enkephalin analogues

Wong, AK; Ross, BP; Chan, YN; Artursson, Per et al.

Part of European Journal of Pharmaceutical Sciences, p. 113-118, 2002

• DOI for Determination of transport in the Caco-2 cell assay of compounds varying in lipophilicity using LC-MS: enhanced transport of Leu-enkephalin analogues

Novel lipoamino acid- and liposaccharide-based system for peptide delivery: Application for oral administration of tumor-selective somatostatin analogues

Toth, I; Malkinson, JP; Flinn, NS; Drouillat, B et al.

Part of Journal of Medicinal Chemistry, p. 4010-1013, 1999

• DOI for Novel lipoamino acid- and liposaccharide-based system for peptide delivery: Application for oral administration of tumor-selective somatostatin analogues

Absorption enhancement in intestinal epithelial Caco-2 monolayers by sodium caprate: Assessment of molecular weight dependence and demonstration of transport routes

Lindmark, T; Schipper, N; Lazorová, Lucia; de, Boer AG et al.

Part of Journal of drug targeting (Print), p. 215-223, 1998

• DOI for Absorption enhancement in intestinal epithelial Caco-2 monolayers by sodium caprate: Assessment of molecular weight dependence and demonstration of transport routes

Quantification and imaging of mannitol transport through Caco-2 cell monolayers using a positron-emitting tracer

Lazorova, Lucia; Gråsjö, Johan; Artursson, Per; Bergström, Mats et al.

Part of Pharmaceutical research, p. 1141-1144, 1998

• DOI for Quantification and imaging of mannitol transport through Caco-2 cell monolayers using a positron-emitting tracer

Transport of an influenza virus vaccine formulation (iscom) in Caco-2 cells

Lazorova, Lucia; Artursson, Per; Engström, Å; Sjölander, A

Part of American Journal of Physiology, 1996

mRNA expression of drug-transporting proteins along the human intestine and comparison with expression in Caco-2 cells

Englund, Gunilla; Rorsman, Fredrik; Rönnblom, Anders; Lazorova, Lucia et al.

2012

Particle transcytosis across intestinal epithelial cells exposed for Yersinia pseudotuberculosis: gene expression analysis and functional studies

Ragnarsson, Eva GE; Göransson, Hanna; Rydåker, Maria; Magnusson, Karl-Eric et al.

Transcellular delivery of peptide antigens across the intestinal epithelial barrier. In Peptide and protein drug research

Artursson, P; Lazorova, L

1998