Per Enblad
Professor at Department of Medical Sciences; Neurosurgery
- E-mail:
- per.enblad@neuro.uu.se
- Visiting address:
- Akademiska sjukhuset, ingång 85 2 tr
- Postal address:
- Akademiska sjukhuset, ing 85 2 tr
751 85 UPPSALA
Download contact information for Per Enblad at Department of Medical Sciences; Neurosurgery
- Academic merits:
- MD PhD
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Publications
Recent publications
- A mathematical model for temporal cerebral blood flow response to acetazolamide evaluated in patients with Moyamoya disease (2024)
- Absolute Contusion Expansion Is Superior to Relative Expansion in Predicting Traumatic Brain Injury Outcomes (2024)
- International e-Delphi survey to define best practice in the reporting of intracranial pressure monitoring recording data (2024)
- Cerebrovascular reactivity (PRx) and optimal cerebral perfusion pressure in elderly with traumatic brain injury (2024)
- Trends in incidence and treatments of spontaneous subarachnoid hemorrhage (2024)
All publications
Articles
- A mathematical model for temporal cerebral blood flow response to acetazolamide evaluated in patients with Moyamoya disease (2024)
- Absolute Contusion Expansion Is Superior to Relative Expansion in Predicting Traumatic Brain Injury Outcomes (2024)
- International e-Delphi survey to define best practice in the reporting of intracranial pressure monitoring recording data (2024)
- Cerebrovascular reactivity (PRx) and optimal cerebral perfusion pressure in elderly with traumatic brain injury (2024)
- Trends in incidence and treatments of spontaneous subarachnoid hemorrhage (2024)
- The effects of cerebral pressure autoregulation status and CPP levels on cerebral metabolism in pediatric traumatic brain injury (2024)
- Adverse events during endovascular treatment of ruptured aneurysms (2023)
- Adverse events associated with microsurgial treatment for ruptured intracerebral aneurysms (2023)
- Thiopental and decompressive craniectomy as last-tier ICP-treatments in aneurysmal subarachnoid hemorrhage (2023)
- Decompressive craniectomy as a second/third-tier intervention in traumatic brain injury (2023)
- A Dedicated 21-Plex Proximity Extension Assay Panel for High-Sensitivity Protein Biomarker Detection Using Microdialysis in Severe Traumatic Brain Injury (2023)
- Evaluation of single-delay arterial spin labeling-based spatial coefficient of variation and histogram-based parameters in relation to cerebrovascular reserve in patients with Moyamoya disease. (2023)
- Lumbar puncture-verified subarachnoid hemorrhage (2023)
- Antithrombotic agent usage before ictus in aneurysmal subarachnoid hemorrhage (2023)
- ASL-MRI-guided evaluation of multiple burr hole revascularization surgery in Moyamoya disease (2023)
- Persistent discrepancies in orbital morphology after surgical treatment of unicoronal craniosynostosis (2023)
- The impact of previous health on the mortality after aneurysmal subarachnoid hemorrhage (2023)
- Intracranial Pressure Variability (2023)
- ICP, CPP, and PRx in traumatic brain injury and aneurysmal subarachnoid hemorrhage (2023)
- ICP, PRx, CPP, and ∆CPPopt in pediatric traumatic brain injury (2023)
- Higher Intracranial Pressure Variability is Associated with Lower Cerebrovascular Resistance in Aneurysmal Subarachnoid Hemorrhage (2023)
- Cerebral Microdialysis Monitoring of Energy Metabolism: Relation to Cerebral Blood Flow and Oxygen Delivery in Aneurysmal Subarachnoid Hemorrhage (2023)
- Editorial: Moyamoya disease - natural history and therapeutic challenges (2023)
- Intracranial lesion features in moderate-to-severe traumatic brain injury (2023)
- Autoregulatory Management in Traumatic Brain Injury (2023)
- Temperature Changes in Poor-Grade Aneurysmal Subarachnoid Hemorrhage (2023)
- Fine tuning of neurointensive care in aneurysmal subarachnoid hemorrhage (2023)
- Cerebral pressure autoregulation and optimal cerebral perfusion pressure during neurocritical care of children with traumatic brain injury (2023)
- Elevated levels of several chemokines in the cerebrospinal fluid of patients with subarachnoid hemorrhage are associated with worse clinical outcome (2023)
- Capturing of intracranial pressure treatment during neurointensive care in patients with acute brain injury using a novel tablet-based method (2022)
- Neurointensive care of traumatic brain injury in the elderly (2022)
- Relationship between T-cell-dependent and T-cell-independent vaccines after neurotrauma (2022)
- Prognosis in moderate-severe traumatic brain injury in a Swedish cohort and external validation of the IMPACT models (2022)
- Central nervous system hemangioblastomas in von Hippel-Lindau disease (2022)
- Cerebral Pressure Autoregulation in Brain Injury and Disorders (2022)
- Low intracranial pressure variability is associated with delayed cerebral ischemia and unfavorable outcome in aneurysmal subarachnoid hemorrhage (2022)
- Post-traumatic hydrocephalus (2022)
- Cerebral Blood Flow and Oxygen Delivery in Aneurysmal Subarachnoid Hemorrhage (2022)
- Intracranial pressure dynamics and cerebral vasomotor reactivity in community-acquired bacterial meningitis during neurointensive care (2022)
- Females Exhibit Better Cerebral Pressure Autoregulation, Less Mitochondrial Dysfunction, and Reduced Excitotoxicity after Severe Traumatic Brain Injury (2022)
- Association of Arterial Metabolic Content with Cerebral Blood Flow Regulation and Cerebral Energy Metabolism-A Multimodality Analysis in Aneurysmal Subarachnoid Hemorrhage (2022)
- Intracranial pressure- and cerebral perfusion pressure threshold-insults in relation to cerebral energy metabolism in aneurysmal subarachnoid hemorrhage (2022)
- Incidence of Non-Syndromic and Syndromic Craniosynostosis in Sweden (2022)
- Temporal patterns of inflammation-related proteins measured in the cerebrospinal fluid of patients with aneurysmal subarachnoid hemorrhage using multiplex Proximity Extension Assay technology (2022)
- Hyperglycolysis as a common cause for elevated lactate in subarachnoid hemorrhage (2021)
- CBF changes and cerebral energy metabolism during hypervolemia, hemodilution, and hypertension therapy in patients with poor-grade subarachnoid hemorrhage (2021)
- Variable Temporal Cerebral Blood Flow Response to Acetazolamide in Moyamoya Patients Measured Using Arterial Spin Labeling (2021)
- Pre-injury chronic alcohol abuse predicts intracranial hemorrhagic progression, unfavorable clinical outcome, and mortality in severe traumatic brain injury (2021)
- Arterial Oxygenation in Traumatic Brain Injury (2021)
- Temporal Dynamics of ICP, CPP, PRx, and CPPopt in High-Grade Aneurysmal Subarachnoid Hemorrhage and the Relation to Clinical Outcome (2021)
- Response to (2021)
- Response to (2021)
- Systemic Hyperthermia in Traumatic Brain Injury—Relation to Intracranial Pressure Dynamics, Cerebral Energy Metabolism, and Clinical Outcome (2021)
- Autoregulatory or Fixed Cerebral Perfusion Pressure Targets in Traumatic Brain Injury (2021)
- Decompressive Craniectomy in Traumatic Brain Injury-Craniectomy-Related and Cranioplasty-Related Complications in a Single Center (2021)
- Pre-injury antithrombotic agents predict intracranial hemorrhagic progression, but not worse clinical outcome in severe traumatic brain injury (2021)
- Fine Tuning of Traumatic Brain Injury Management in Neurointensive Care-Indicative Observations and Future Perspectives (2021)
- Does Coronal Suturectomies and Occipital Barrel Staves Make a Difference in Early Reconstruction for Sagittal Craniosynostosis? (2021)
- Temporal effects of barbiturate coma on intracranial pressure and compensatory reserve in children with traumatic brain injury (2021)
- High Intravascular Signal Arterial Transit Time Artifacts Have Negligible Effects on Cerebral Blood Flow and Cerebrovascular Reserve Capacity Measurement Using Single Postlabel Delay Arterial Spin-Labeling in Patients with Moyamoya Disease (2020)
- Cerebral Blood Flow Measurement in Healthy Children and Children Suffering Severe Traumatic Brain Injury (2020)
- Arterial lactate in traumatic brain injury (2020)
- In Reply (2020)
- Intracranial pressure variability (2020)
- Mild hyperventilation in traumatic brain injury (2020)
- Blood Pressure Variability and Optimal Cerebral Perfusion Pressure-New Therapeutic Targets in Traumatic Brain Injury (2020)
- Intracranial Pressure Dynamics and Cerebral Vasomotor Reactivity in Coronavirus Disease 2019 Patient With Acute Encephalitis (2020)
- Association of the bleeding time test with aspects of traumatic brain injury in patients with alcohol use disorder (2020)
- Secondary Coronal Synostosis After Early Surgery for Sagittal Craniosynostosis (2020)
- Intracranial pressure-based barbiturate coma treatment in children with refractory intracranial hypertension due to traumatic brain injury (2020)
- Intracranial pressure elevations in diffuse axonal injury (2019)
- Forewarning of hypotensive events using a Bayesian artificial neural network in neurocritical care (2019)
- Monitoring of Protein Biomarkers of Inflammation in Human Traumatic Brain Injury Using Microdialysis and Proximity Extension Assay Technology in Neurointensive Care (2019)
- Temporal Dynamics of Cerebral Blood Flow During the Acute Course of Severe Subarachnoid Hemorrhage Studied by Bedside Xenon-Enhanced CT (2019)
- Clinical outcome and prognostic factors in elderly traumatic brain injury patients receiving neurointensive care (2019)
- Temporal Neurophysiological Dynamics in Traumatic Brain Injury (2019)
- High Arterial Glucose is Associated with Poor Pressure Autoregulation, High Cerebral Lactate/Pyruvate Ratio and Poor Outcome Following Traumatic Brain Injury (2019)
- Interleukin-6 Levels in Cerebrospinal Fluid and Plasma in Patients with Severe Spontaneous Subarachnoid Hemorrhage (2019)
- Dual lumen balloon catheter - An effective substitute for two single lumen catheters in treatment of vascular targets with challenging anatomy (2018)
- Continuous monitoring of intracranial compliance in neurointensive care (Editorial by invitation) (2018)
- Response to "Letter to the Editor" by R. Dhar (2018)
- Hemodynamic Disturbances in the Early Phase After Subarachnoid Hemorrhage (2018)
- Effect of HHH-Therapy on Regional CBF after Severe Subarachnoid Hemorrhage Studied by Bedside Xenon-Enhanced CT (2018)
- Optimal Cerebral Perfusion Pressure in Centers With Different Treatment Protocols (2018)
- A Dedicated 21-Plex Pea Panel For High-Sensitive Protein Biomarker Detection Using Micro-Dialysis In Traumatic Brain Injury (2018)
- Early low cerebral blood flow and high cerebral lactate (2018)
- Letter to the Editor: Decompressive craniectomy in traumatic brain injury—the discussion must continue (2018)
- Decompressive craniectomy in traumatic brain injury (2018)
- Neurointensive care of patients with cerebral venous sinus thrombosis and intracerebral haemorrhage (2018)
- Extended anatomical grading in diffuse axonal injury using MRI (2017)
- The effects of ventricular drainage on the intracranial pressure signal and the pressure reactivity index (2017)
- Increased risk of critical CBF levels in SAH patients with actual CPP below calculated optimal CPP (2017)
- Pneumococcal polysaccharide vaccination administered early after neurotrauma or neurosurgery (2017)
- An evaluation of the mixed pediatric unit for blood loss replacement in pediatric craniofacial surgery (2017)
- Predictive Factors That May Contribute to Secondary Insults With Nursing Interventions in Adults With Traumatic Brain Injury (2017)
- The influence of hyperthermia on intracranial pressure, cerebral oximetry and cerebral metabolism in traumatic brain injury (2017)
- The Correlation between Cerebral Blood Flow Measured by Bedside Xenon-CT and Brain Chemistry Monitored by Microdialysis in the Acute Phase following Subarachnoid Hemorrhage (2017)
- Interleukin-6 levels in cerebrospinal fluid and plasma in patients with severe spontaneous subarachnoid hemorrhage (2017)
- Ventriculostomy-related infections in subarachnoid hemorrhage patients - a retrospective study of incidence, etiology, and antimicrobial therapy (2017)
- Positive correlation between occlusion rate and nidus size of proton beam treated brain arteriovenous malformations (AVMs) (2016)
- Bedside Xenon-CT Shows Lower CBF in SAH Patients with Impaired CBF Pressure Autoregulation as Defined by Pressure Reactivity Index (PRx) (2016)
- Telemetric intracranial pressure monitoring (2016)
- Promising clinical outcome of elderly with TBI after modern neurointensive care (2016)
- An optimal frequency range for assessing the pressure reactivity index in patients with traumatic brain injury (2015)
- Updated periodic evaluation of standardized neurointensive care shows that it is possible to maintain a high level of favorable outcome even with increasing mean age (2015)
- Refined microdialysis method for protein biomarker sampling in acute brain injury in the neurointensive care setting (2014)
- Acute neurosurgery for traumatic brain injury by general surgeons in Swedish county hospitals (2014)
- Cerebral microdialysis for protein biomarker monitoring in the neurointensive care setting - a technical approach (2014)
- New Microdialysis Method for Protein Biomarker Sampling in the Neurointensive Care Setting (2014)
- Should the Neurointensive Care Management of Traumatic Brain Injury Patients be Individualized According to Autoregulation Status and Injury Subtype? (2014)
- Monitoring of beta-Amyloid Dynamics after Human Traumatic Brain Injury (2014)
- Secondary insults related to nursing interventions in neurointensive care (2014)
- Brain tissue oxygenation and cerebral metabolic patterns in focal and diffuse traumatic brain injury (2014)
- Outcome from spontaneous subarachnoid haemorrhage (2014)
- Imaging of cerebral blood flow in patients with severe traumatic brain injury in the neurointensive care (2014)
- Monitoring of Cerebral Blood Flow and Metabolism Bedside in Patients with Subarachnoid Hemorrhage - A Xenon-CT and Microdialysis Study (2014)
- The Neurological Wake-up Test Does not Alter Cerebral Energy Metabolism and Oxygenation in Patients with Severe Traumatic Brain Injury (2014)
- Introduction of the Uppsala Traumatic Brain Injury register for regular surveillance of patient characteristics and neurointensive care management including secondary insult quantification and clinical outcome (2013)
- Health-related quality of life at median 12 months after aneurysmal subarachnoid hemorrhage, measured with EuroQoL-5D (2013)
- Monitoring and Sedation Differences in the Management of Severe Head Injury and Subarachnoid Hemorrhage Among Neurocritical Care Centers (2013)
- Improved outcome of patients with severe thalamic hemorrhage treated with cerebrospinal fluid drainage and neurocritical care during 1990-1994 and 2005-2009 (2013)
- Interstitial F2-Isoprostane 8-Iso-PGF2α As a Biomarker of Oxidative Stress after Severe Human Traumatic Brain Injury (2012)
- An evaluation of three measures of intracranial compliance in traumatic brain injury patients (2012)
- Monitoring of amyloid-beta dynamics after human traumatic brain injury (2012)
- The use of nurse checklists in a bedside computer-based information system to focus on avoiding secondary insults in neurointensive care (2012)
- Brain Tissue Oxygenation and Cerebral Perfusion Pressure Thresholds of Ischemia in a Standardized Pig Brain Death Model (2012)
- Wake-up test and stress hormone levels in patients with brain injury (2012)
- The neurological wake-up test increases stress hormone levels in patients with severe traumatic brain injury (2012)
- Prognostic factors and long-term outcome following surgical treatment of 76 patients with spontaneous cerebellar haematoma (2012)
- Neurointensive care of patients with severe community-acquired meningitis (2011)
- Favorable Outcome in Traumatic Brain Injury Patients With Impaired Cerebral Pressure Autoregulation When Treated at Low Cerebral Perfusion Pressure Levels (2011)
- Posterior cranial vault expansion performed with rapid distraction and time-reduced consolidation in infants with syndromic craniosynostosis (2011)
- Standardized experimental brain death model for studies of intracranial dynamics, organ preservation, and organ transplantation in the pig (2011)
- Outcome After Spontaneous Subarachnoid Hemorrhage Measured With the EQ-5D (2011)
- Surgical treatment of patients with unilateral cerebellar infarcts (2011)
- Clinical outcome following surgical treatment for bilateral cerebellar infarction (2011)
- Neurosurgical Gram-Negative Bacillary Ventriculitis and Meningitis (2011)
- Neurosurgical gram-negative bacillary ventriculitis and meningitis: a retrospective study evaluating the efficacy of intraventricular gentamicin therapy in 31 consecutive cases. (2011)
- Cortisol and adrenocorticotropic hormone dynamics in the acute phase of subarachnoid haemorrhage (2011)
- Relation between brain interstitial and systemic glucose concentrations after subarachnoid hemorrhage (2011)
- The brain monitoring with Information Technology (BrainIT) collaborative network (2010)
- Brain tissue oxygen monitoring (2010)
- Patient age and vasospasm after subarachnoid hemorrhage (2010)
- Neurointensive care is justified in elderly patients with severe subarachnoid hemorrhage--an outcome and secondary insults study (2010)
- Metabolic effects of a late hypotensive insult combined with reduced intracranial compliance following traumatic brain injury in the rat (2010)
- Brain energy metabolism in patients with spontaneous subarachnoid hemorrhage and global cerebral edema (2010)
- Skull base and maxillofacial fractures (2009)
- Temporally resolved differential proteomic analysis of human ventricular CSF for monitoring traumatic brain injury biomarker candidates. (2009)
- Monitoring of brain interstitial total tau and beta amyloid proteins by microdialysis in patients with traumatic brain injury (2009)
- Cerebral energy failure following experimental cardiac arrest (2009)
- Intracerebral monitoring in comatose patients treated withhypothermia after cardiac arrest (2009)
- Patients with spontaneous subarachnoid haemorrhage (2009)
- Microdialysis patterns in subarachnoid hemorrhage patients with focus on ischemic events and brain interstitial glutamine levels (2009)
- Relationship between intracranial hemodynamics and microdialysis markers of energy metabolism and glutamate-glutamine turnover in patients with subarachnoid hemorrhage (2009)
- Response (2009)
- Effects of the neurological wake-up test on intracranial pressure and cerebral perfusion pressure in brain-injured patients (2009)
- Federating distributed clinical data for the prediction of adverse hypotensive events (2009)
- Temporal patterns of interstitial pyruvate and amino acids after subarachnoid haemorrhage are related to the level of consciousness (2009)
- Multicenter clinical assessment of the raumedic Neurovent-P intracranial pressure sensor (2008)
- Intranasal selective brain cooling in pigs (2008)
- Temperature disturbances in traumatic brain injury (2008)
- Nonischemic energy metabolic crisis in acute brain injury (2008)
- The use of hyperventilation theraphy after traumatic brain injury in Europe (2008)
- International Subarachnoid Aneurysm Trial of neurosurgical clipping versus endovascular coiling (2008)
- Treatment of cerebrospinal fluid shunt infections in children using systemic and intraventricular antibiotic therapy in combination with externalization of the ventricular catheter (2007)
- Neurointensive care management of raised intracranial pressure caused by severe valproic acid intoxication (2007)
- Secondary insults in subarachnoid hemorrhage (2007)
- Cerebral glutamine and glutamate levels in relation to compromised energy metabolism (2007)
- Cerebral perfusion pressure between 50 and 60 mm Hg may be beneficial in head-injured patients (2005)
- Pressure reactivity as a guide in the treatment of cerebral perfusion pressure in patients with brain trauma (2005)
- Efficacy and safety of cefotaxime in combination with metronidazole for empirical treatment of brain abscess in clinical practice (2004)
- Clinical outcome after endovascular coil embolization in elderly patients with subarachnoid hemorrhage (2004)
- Fractionated, stereotactic proton beam treatment of cerebral arterionvenous malformations. (2004)
- Cerebral blood flow and metabolism after cardiopulmonary resuscitation. A pathophysiologic and prognostic positron emission tomography pilot study. (2003)
- Prevention of secondary insults in neurointensive care of traumatic brain injury (2003)
- Outcome after traumatic brain injury improved by an organized secondary insult program and standardized neurointensive care (2002)
- Modulation of phenotype and induction of irregular vessels accompany high tumorigenic potential of clonal human glioma cells xenografted to nude-rat brain (2000)
- Intracranial pressure elevations in diffuse axonal injury are associated with non-hemorrhagic MR lesions in central mesencephalic structures
- Machine learning based prediction of imminent ICP insults during neurocritical care of traumatic brain injury
- Challenges in CATE estimation for NCCU data
- Cerebrovascular reactivity (PRx) and optimal cerebral perfusion pressure in elderly with traumatic brain injury.
- Decreased T-lymphocyte response to T-cell-dependent vaccines after neurotrauma or neurosurgery
- Deep learning-based segmentation of intracranial volume and calvarial bones in pre- and postoperative CT-images of children with sagittal craniosynostosis
Chapters
- BrainIT collaborative network (2009)
- The brain monitoring with information technology (BrainIT) collaborative network (2009)
Conferences
- Visualizing Cerebrovascular Autoregulation Insults and Their Association with Outcome in Adult and Paediatric Traumatic Brain Injury (2018)
- Initial In-Vitro Trial for Intra-Cranial Pressure Monitoring Using Subdermal Proximity-Coupled Split-Ring Resonator (2018)
- A Four-Layer Phantom for Testing In-Vitro Microwave-Based Sensing Approach in Intra-Cranial Pressure Monitoring (2018)
- MRI analysis of diffuse axonal injury - Hemorrhagic lesions in the mesencephalon idicate poor long-term outcome (2016)
- Supporting clinical trials to predict adverse events in the brain trauma domain (2012)
