Michael Häggman

A systematic analysis of the impact of data variation on AI-based histopathological grading of prostate cancer

Fuhlert, Patrick; Westhaeusser, Fabian; Dietrich, Esther; Lennartz, Maximilian et al.

Part of Medical Image Analysis, 2026

• DOI for A systematic analysis of the impact of data variation on AI-based histopathological grading of prostate cancer
• Download full text (pdf) of A systematic analysis of the impact of data variation on AI-based histopathological grading of prostate cancer

Preclinical development and clinical safety assessment of a synthetic peptide conjugate enabling endogenous antibody binding to promote innate receptor engagement

Fletcher, Erika A. K.; Cordfunke, Robert A.; Nasi, Aikaterini; Törnqvist, Gunilla et al.

Part of Molecular Therapy Oncology, 2025

• DOI for Preclinical development and clinical safety assessment of a synthetic peptide conjugate enabling endogenous antibody binding to promote innate receptor engagement
• Download full text (pdf) of Preclinical development and clinical safety assessment of a synthetic peptide conjugate enabling endogenous antibody binding to promote innate receptor engagement

Time Dependence of Outcomes in the SPCG-4 Randomized Trial Comparing Radical Prostatectomy and Watchful Waiting in Early Prostate Cancer.

Holmberg, Lars; Garmo, H.; Andersson, Sven-Olov; Andrén, Ove et al.

Part of European Urology, p. 554-558, 2025

• DOI for Time Dependence of Outcomes in the SPCG-4 Randomized Trial Comparing Radical Prostatectomy and Watchful Waiting in Early Prostate Cancer.
• Download full text (pdf) of Time Dependence of Outcomes in the SPCG-4 Randomized Trial Comparing Radical Prostatectomy and Watchful Waiting in Early Prostate Cancer.

Radical Prostatectomy or Watchful Waiting in Early Prostate Cancer

Holmberg, Lars; Garmo, Hans; Andersson, Swen-Olof; Andrén, Ove et al.

Part of New England Journal of Medicine, p. 1362-1364, 2024

• DOI for Radical Prostatectomy or Watchful Waiting in Early Prostate Cancer

Robust, credible, and interpretable AI-based histopathological prostate cancer grading

Westhaeusser, Fabian; Fuhlert, Patrick; Dietrich, Esther; Lennartz, Maximilian et al.

Part of medRxiv, 2024

• DOI for Robust, credible, and interpretable AI-based histopathological prostate cancer grading
• Download full text (pdf) of Robust, credible, and interpretable AI-based histopathological prostate cancer grading

A systematic analysis of the impact of data variation on AI-based histopathological grading of prostate cancer

Fuhlert, Patrick; Westhaeusser, Fabian; Dietrich, Esther; Lennartz, Maximilian et al.

Part of Medical Image Analysis, 2026

• DOI for A systematic analysis of the impact of data variation on AI-based histopathological grading of prostate cancer
• Download full text (pdf) of A systematic analysis of the impact of data variation on AI-based histopathological grading of prostate cancer

Preclinical development and clinical safety assessment of a synthetic peptide conjugate enabling endogenous antibody binding to promote innate receptor engagement

Fletcher, Erika A. K.; Cordfunke, Robert A.; Nasi, Aikaterini; Törnqvist, Gunilla et al.

Part of Molecular Therapy Oncology, 2025

• DOI for Preclinical development and clinical safety assessment of a synthetic peptide conjugate enabling endogenous antibody binding to promote innate receptor engagement
• Download full text (pdf) of Preclinical development and clinical safety assessment of a synthetic peptide conjugate enabling endogenous antibody binding to promote innate receptor engagement

Time Dependence of Outcomes in the SPCG-4 Randomized Trial Comparing Radical Prostatectomy and Watchful Waiting in Early Prostate Cancer.

Holmberg, Lars; Garmo, H.; Andersson, Sven-Olov; Andrén, Ove et al.

Part of European Urology, p. 554-558, 2025

• DOI for Time Dependence of Outcomes in the SPCG-4 Randomized Trial Comparing Radical Prostatectomy and Watchful Waiting in Early Prostate Cancer.
• Download full text (pdf) of Time Dependence of Outcomes in the SPCG-4 Randomized Trial Comparing Radical Prostatectomy and Watchful Waiting in Early Prostate Cancer.

Radical Prostatectomy or Watchful Waiting in Early Prostate Cancer

Holmberg, Lars; Garmo, Hans; Andersson, Swen-Olof; Andrén, Ove et al.

Part of New England Journal of Medicine, p. 1362-1364, 2024

• DOI for Radical Prostatectomy or Watchful Waiting in Early Prostate Cancer

Robust, credible, and interpretable AI-based histopathological prostate cancer grading

Westhaeusser, Fabian; Fuhlert, Patrick; Dietrich, Esther; Lennartz, Maximilian et al.

Part of medRxiv, 2024

• DOI for Robust, credible, and interpretable AI-based histopathological prostate cancer grading
• Download full text (pdf) of Robust, credible, and interpretable AI-based histopathological prostate cancer grading

Focal high-intensity focused ultrasound therapy for localized prostate cancer: An interim analysis of the multinational FASST study

Ladjevardi, Sam; Ebner, Anna; Femic, Aleksandar; Huebner, Nicolai A. et al.

Part of European Journal of Clinical Investigation, 2024

• DOI for Focal high-intensity focused ultrasound therapy for localized prostate cancer: An interim analysis of the multinational FASST study
• Download full text (pdf) of Focal high-intensity focused ultrasound therapy for localized prostate cancer: An interim analysis of the multinational FASST study

Next generation pan-cancer blood proteome profiling using proximity extension assay

Alvez, Maria Bueno; Edfors, Fredrik; von Feilitzen, Kalle; Zwahlen, Martin et al.

Part of Nature Communications, 2023

• DOI for Next generation pan-cancer blood proteome profiling using proximity extension assay
• Download full text (pdf) of Next generation pan-cancer blood proteome profiling using proximity extension assay

P-score in preoperative biopsies accurately predicts P-score in final pathology at radical prostatectomy in patients with localized prostate cancer

Röbeck, Pontus; Xu, Lidi; Ahmed, Dilruba; Dragomir, Anca et al.

Part of The Prostate, p. 831-839, 2023

• DOI for P-score in preoperative biopsies accurately predicts P-score in final pathology at radical prostatectomy in patients with localized prostate cancer
• Download full text (pdf) of P-score in preoperative biopsies accurately predicts P-score in final pathology at radical prostatectomy in patients with localized prostate cancer

Multiplex protein analysis and ensemble machine learning methods of fine needle aspirates from prostate cancer patients reveal potential diagnostic signatures associated with tumour grade

Röbeck, Pontus; Franzén, Bo; Cantera-Ahlman, Rafaele; Dragomir, Anca et al.

Part of Cytopathology, p. 286-294, 2023

• DOI for Multiplex protein analysis and ensemble machine learning methods of fine needle aspirates from prostate cancer patients reveal potential diagnostic signatures associated with tumour grade
• Download full text (pdf) of Multiplex protein analysis and ensemble machine learning methods of fine needle aspirates from prostate cancer patients reveal potential diagnostic signatures associated with tumour grade

A Novel Risk Score (P-score) Based on a Three-Gene Signature, for Estimating the Risk of Prostate Cancer-Specific Mortality

Söderdahl, Fabian; Xu, Li-Di; Bring, Johan; Häggman, Michael

Part of Research and Reports in Urology, p. 203-217, 2022

• DOI for A Novel Risk Score (P-score) Based on a Three-Gene Signature, for Estimating the Risk of Prostate Cancer-Specific Mortality
• Download full text (pdf) of A Novel Risk Score (P-score) Based on a Three-Gene Signature, for Estimating the Risk of Prostate Cancer-Specific Mortality

Bi-parametric MRI/TRUS fusion targeted repeat biopsy after systematic 10-12 core TRUS-guided biopsy reveals more significant prostate cancer especially in anteriorly located tumors

Häggman, Michael; Dahlman, Par; Ahlberg, Mats; Liss, Per et al.

Part of Acta Radiologica Open, 2022

• DOI for Bi-parametric MRI/TRUS fusion targeted repeat biopsy after systematic 10-12 core TRUS-guided biopsy reveals more significant prostate cancer especially in anteriorly located tumors
• Download full text (pdf) of Bi-parametric MRI/TRUS fusion targeted repeat biopsy after systematic 10-12 core TRUS-guided biopsy reveals more significant prostate cancer especially in anteriorly located tumors

Noninvasive detection of any-stage cancer using free glycosaminoglycans

Bratulic, Sinisa; Limeta, Angelo; Dabestani, Saeed; Birgisson, Helgi et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, 2022

• DOI for Noninvasive detection of any-stage cancer using free glycosaminoglycans
• Download full text (pdf) of Noninvasive detection of any-stage cancer using free glycosaminoglycans

Androgen deprivation monotherapy usage in non-metastatic prostate cancer: results from eight European countries

Mitropoulos, Dionysios; Chlosta, Piotr; Häggman, Michael; Ström, Torbjörn et al.

Part of Central European Journal of Urology, p. 161-168, 2021

• DOI for Androgen deprivation monotherapy usage in non-metastatic prostate cancer: results from eight European countries

Carbon Flux as a Measure of Prostate Cancer Aggressiveness: [¹¹C]-Acetate PET/CT

Regula, Naresh; Honarvar, Hadis; Lubberink, Mark; Jorulf, Håkan et al.

Part of International Journal of Medical Sciences, p. 214-223, 2020

• DOI for Carbon Flux as a Measure of Prostate Cancer Aggressiveness: [¹¹C]-Acetate PET/CT
• Download full text (pdf) of Carbon Flux as a Measure of Prostate Cancer Aggressiveness: [¹¹C]-Acetate PET/CT

Periprocedural outcome after laparoscopic partial nephrectomy versus radiofrequency ablation for T1 renal tumors: A modified R.E.N.A.L nephrometry score adjusted comparison

Acosta Ruiz, Vanessa; Ladjevardi, Sam; Brekkan, Einar; Häggman, Michael et al.

Part of Acta Radiologica, p. 260-268, 2019

• DOI for Periprocedural outcome after laparoscopic partial nephrectomy versus radiofrequency ablation for T1 renal tumors: A modified R.E.N.A.L nephrometry score adjusted comparison

Radical Prostatectomy or Watchful Waiting in Prostate Cancer: 29-Year Follow-up

Bill-Axelson, Anna; Holmberg, Lars; Garmo, Hans; Taari, Kimmo et al.

Part of New England Journal of Medicine, p. 2319-2329, 2018

• DOI for Radical Prostatectomy or Watchful Waiting in Prostate Cancer: 29-Year Follow-up

U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.

Glimelius, Bengt; Melin, Beatrice; Enblad, Gunilla; Alafuzoff, Irina et al.

Part of Acta Oncologica, p. 187-194, 2018

• DOI for U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.
• Download full text (pdf) of U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.

Changes of arterial pressure following relief of obstruction in adults with hydronephrosis

Al-Mashhadi, Ammar; Häggman, Michael; Läckgren, Göran; Ladjevardi, Sam et al.

Part of Upsala Journal of Medical Sciences, p. 216-224, 2018

• DOI for Changes of arterial pressure following relief of obstruction in adults with hydronephrosis
• Download full text (pdf) of Changes of arterial pressure following relief of obstruction in adults with hydronephrosis

Additional value of magnetic resonance-targeted biopsies to standard transrectal ultrasound-guided biopsies for detection of clinically significant prostate cancer

von Below, Catrin; Wassberg, Cecilia; Norberg, Mona; Tolf, Anna et al.

Part of Scandinavian journal of urology, p. 107-113, 2017

• DOI for Additional value of magnetic resonance-targeted biopsies to standard transrectal ultrasound-guided biopsies for detection of clinically significant prostate cancer

An Intraprostatic Modified Release Formulation of Antiandrogen 2-Hydroxyflutamide for Localized Prostate Cancer

Tammela, T L; Häggman, Michael; Ladjevardi, Sam; Taari, K et al.

Part of Journal of Urology, p. 1333-1339, 2017

• DOI for An Intraprostatic Modified Release Formulation of Antiandrogen 2-Hydroxyflutamide for Localized Prostate Cancer

Dynamic Imaging of Prostate Cancer with 11C-acetate PET/CT

Regula, Naresh Kumar; Lubberink, Mark; Jorulf, Håkan; Ladjevardi, Sam et al.

Part of Journal of Nuclear Medicine, 2017

Quantification of metabolite concentrations in benign and malignant prostate tissues using 3D proton MR spectroscopic imaging

Weis, Jan; von Below, Catrin; Tolf, Anna; Ortiz-Nieto, Francisco et al.

Part of Journal of Magnetic Resonance Imaging, p. 1232-1240, 2017

• DOI for Quantification of metabolite concentrations in benign and malignant prostate tissues using 3D proton MR spectroscopic imaging

Malignant lipogenesis defined by ¹¹C-acetate PET/CT predicts prostate cancer-specific survival in patients with biochemical relapse after prostatectomy

Regula, Naresh; Häggman, Michael; Johansson, Silvia; Sörensen, Jens

Part of European Journal of Nuclear Medicine and Molecular Imaging, p. 2131-2138, 2016

• DOI for Malignant lipogenesis defined by ¹¹C-acetate PET/CT predicts prostate cancer-specific survival in patients with biochemical relapse after prostatectomy

Radical Prostatectomy or Watchful Waiting in Early Prostate Cancer

Bill-Axelson, Anna; Holmberg, Lars; Garmo, Hans; Rider, Jennifer R. et al.

Part of New England Journal of Medicine, p. 932-942, 2014

• DOI for Radical Prostatectomy or Watchful Waiting in Early Prostate Cancer

Prostate biopsy sampling causes hematogenous dissemination of epithelial cellular material

Ladjevardi, Sam; Auer, Gert; Castro, Juan; Ericsson, Christer et al.

Part of Disease Markers, p. 707529, 2014

• DOI for Prostate biopsy sampling causes hematogenous dissemination of epithelial cellular material
• Download full text (pdf) of Prostate biopsy sampling causes hematogenous dissemination of epithelial cellular material

A Comparison of Different Imaging Techniques for Localisation of Cancers in the Prostate

Ladjevardi, Sam; Weis, Jan; Sörensen, Jens; Tolf, Anna et al.

Part of Open Prostate Cancer Journal, p. 1-6, 2014

• DOI for A Comparison of Different Imaging Techniques for Localisation of Cancers in the Prostate

Long-term Survival and Biomarker Correlates of Tasquinimod Efficacy in a Multicenter Randomized Study of Men with Minimally Symptomatic Metastatic Castration-Resistant Prostate Cancer.

Armstrong, A J; Häggman, Michael; Stadler, W M; Gingrich, J R et al.

Part of Clinical Cancer Research, p. 6891-6901, 2013

• DOI for Long-term Survival and Biomarker Correlates of Tasquinimod Efficacy in a Multicenter Randomized Study of Men with Minimally Symptomatic Metastatic Castration-Resistant Prostate Cancer.

Tasquinimod mechanism of action biomarkers: correlation with pfs and survival in men with metastatic castrate resistant prostate cancer treated in a randomized phase 2 trial

Carducci, M.; Armstrong, A.; Haggman, Michael; Stadler, W. M. et al.

Part of Annals of Oncology, p. 303-303, 2012

Radical Prostatectomy versus Watchful Waiting in Early Prostate Cancer

Bill-Axelson, Anna; Holmberg, Lars; Ruutu, Mirja; Garmo, Hans et al.

Part of New England Journal of Medicine, p. 1708-1717, 2011

• DOI for Radical Prostatectomy versus Watchful Waiting in Early Prostate Cancer

MR spectroscopy of the human prostate using surface coil at 3 T: Metabolite ratios, age-dependent effects, and diagnostic possibilities

Weis, Jan; Jorulf, Håkan; Bergman, Antonina; Ortiz-Nieto, Francisco et al.

Part of Journal of Magnetic Resonance Imaging, p. 1277-1284, 2011

• DOI for MR spectroscopy of the human prostate using surface coil at 3 T: Metabolite ratios, age-dependent effects, and diagnostic possibilities

Phase II Randomized, Double-Blind, Placebo-Controlled Study of Tasquinimod in Men With Minimally Symptomatic Metastatic Castrate-Resistant Prostate Cancer

Pili, Roberto; Häggman, Michael; Stadler, Walter M.; Gingrich, Jeffrey R. et al.

Part of Journal of Clinical Oncology, p. 4022-4028, 2011

• DOI for Phase II Randomized, Double-Blind, Placebo-Controlled Study of Tasquinimod in Men With Minimally Symptomatic Metastatic Castrate-Resistant Prostate Cancer

Laparoscopic nephropexy exposes a possible underlying pathogenic mechanism and allows successful treatment with tissue gluing of the kidney and fixation of the colon to the lateral abdominal wall

Wadström, Jonas; Häggman, Michael

Part of International Brazilian journal of urology : official journal of the Brazilian Society of Urology, p. 10-17, 2010

• DOI for Laparoscopic nephropexy exposes a possible underlying pathogenic mechanism and allows successful treatment with tissue gluing of the kidney and fixation of the colon to the lateral abdominal wall

Open-label, clinical phase I studies of tasquinimod in patients with castration-resistant prostate cancer

Bratt, O.; Häggman, Michael; Ahlgren, G.; Nordle, O. et al.

Part of British Journal of Cancer, p. 1233-40, 2009

• DOI for Open-label, clinical phase I studies of tasquinimod in patients with castration-resistant prostate cancer

Personalized prediction of tumor response and cancer progression on prostate needle biopsy

Donovan, Michael J.; Khan, Faisal M.; Fernandez, Gerardo; Mesa-Tejada, Ricardo et al.

Part of Journal of Urology, p. 125-132, 2009

• DOI for Personalized prediction of tumor response and cancer progression on prostate needle biopsy

Radical prostatectomy versus watchful waiting in localized prostate cancer: the Scandinavian prostate cancer group-4 randomized trial

Bill-Axelson, Anna; Holmberg, Lars; Filén, Frej; Ruutu, Mirja et al.

Part of Journal of the National Cancer Institute, p. 1144-54, 2008

• DOI for Radical prostatectomy versus watchful waiting in localized prostate cancer: the Scandinavian prostate cancer group-4 randomized trial

"Between Men": A psychosocial rehabilitation programme for men with prostate cancer

Berglund, Gunilla; Petersson, Lena-Marie; Eriksson, Karin C.; Wallenius, Imke et al.

Part of Acta Oncologica, p. 83-89, 2007

• DOI for "Between Men": A psychosocial rehabilitation programme for men with prostate cancer

Positron emission tomography with C11-acetate for tumor detection and localization in patients with prostate-specific antigen relapse after radical prostatectomy

Sandblom, Gabriel; Sörensen, Jens; Lundin, Niclas; Häggman, Michael et al.

Part of Urology, p. 996-1000, 2006

• DOI for Positron emission tomography with C11-acetate for tumor detection and localization in patients with prostate-specific antigen relapse after radical prostatectomy

Prediction of percent Gleason grade 4/5 by multiple core biopsies

Glaessgen, Axel; Busch, Christer; Norberg, Mona; Häggman, Michael et al.

Part of Scandinavian Journal of Urology and Nephrology, p. 465-471, 2006

• DOI for Prediction of percent Gleason grade 4/5 by multiple core biopsies

Radical prostatectomy versus watchful waiting in early prostate cancer

Bill-Axelson, Anna; Holmberg, Lars; Ruutu, Mirja; Häggman, Michael et al.

Part of New England Journal of Medicine, p. 1977-1944, 2005

• DOI for Radical prostatectomy versus watchful waiting in early prostate cancer

The significance of tumor heterogeneity for prediction of DNA ploidy of prostate cancer.

Häggarth, Lars; Auer, Gert; Busch, Christer; Norberg, Mona et al.

Part of Scand J Urol Nephrol, p. 387-92, 2005

Prediction of the volume of large prostate cancers by multiple core biopsies.

Häggarth, Lars; Busch, Christer; Norberg, Mona; Häggman, Michael et al.

Part of Scand J Urol Nephrol, p. 380-6, 2005

A randomized trial comparing radical prostatectomy with watchful waiting in early prostate cancer

Holmberg, Lars; Bill-Axelson, Anna; Helgesen, Fred; Salo, Jaakko O. et al.

Part of New England Journal of Medicine, p. 781-789, 2002

Additional value of magnetic resonance targeted biopsies to standard transrectal ultrasound guided biopsies for detection of clinical significant prostate cancer

von Below, Catrin; Wassberg, Cecilia; Norberg, Mona; Tolf, Anna et al.