Göran Akusjärvi
Professor at Department of Medical Biochemistry and Microbiology; Infection and Immunity; Tanel Punga
- Mobile phone:
- +46 73 102 10 99
- E-mail:
- Goran.Akusjarvi@imbim.uu.se
- Visiting address:
- BMC
Husargatan 3
752 37 UPPSALA - Postal address:
- Box 582
751 23 UPPSALA

Publications
Recent publications
Part of Journal of Biological Chemistry, 2023
- DOI for The RNA-binding protein ZC3H11A interacts with the nuclear poly(A)-binding protein PABPN1 and alters polyadenylation of viral transcripts
- Download full text (pdf) of The RNA-binding protein ZC3H11A interacts with the nuclear poly(A)-binding protein PABPN1 and alters polyadenylation of viral transcripts
Fragile X-Related Protein FXR1 Controls Human Adenovirus Capsid mRNA Metabolism
Part of Journal of Virology, 2023
ZC3H11A loss of function enhances NF-κB signaling through defective IκBα protein expression
Part of Frontiers in Immunology, 2022
- DOI for ZC3H11A loss of function enhances NF-κB signaling through defective IκBα protein expression
- Download full text (pdf) of ZC3H11A loss of function enhances NF-κB signaling through defective IκBα protein expression
Ixovex-1, a novel oncolytic E1B-mutated adenovirus
Part of Cancer Gene Therapy, p. 1628-1635, 2022
- DOI for Ixovex-1, a novel oncolytic E1B-mutated adenovirus
- Download full text (pdf) of Ixovex-1, a novel oncolytic E1B-mutated adenovirus
The Human Adenovirus 2 Transcriptome: An Amazing Complexity of Alternatively Spliced mRNAs
Part of Journal of Virology, 2021
- DOI for The Human Adenovirus 2 Transcriptome: An Amazing Complexity of Alternatively Spliced mRNAs
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All publications
Articles in journal
Part of Journal of Biological Chemistry, 2023
- DOI for The RNA-binding protein ZC3H11A interacts with the nuclear poly(A)-binding protein PABPN1 and alters polyadenylation of viral transcripts
- Download full text (pdf) of The RNA-binding protein ZC3H11A interacts with the nuclear poly(A)-binding protein PABPN1 and alters polyadenylation of viral transcripts
Fragile X-Related Protein FXR1 Controls Human Adenovirus Capsid mRNA Metabolism
Part of Journal of Virology, 2023
ZC3H11A loss of function enhances NF-κB signaling through defective IκBα protein expression
Part of Frontiers in Immunology, 2022
- DOI for ZC3H11A loss of function enhances NF-κB signaling through defective IκBα protein expression
- Download full text (pdf) of ZC3H11A loss of function enhances NF-κB signaling through defective IκBα protein expression
Ixovex-1, a novel oncolytic E1B-mutated adenovirus
Part of Cancer Gene Therapy, p. 1628-1635, 2022
- DOI for Ixovex-1, a novel oncolytic E1B-mutated adenovirus
- Download full text (pdf) of Ixovex-1, a novel oncolytic E1B-mutated adenovirus
The Human Adenovirus 2 Transcriptome: An Amazing Complexity of Alternatively Spliced mRNAs
Part of Journal of Virology, 2021
- DOI for The Human Adenovirus 2 Transcriptome: An Amazing Complexity of Alternatively Spliced mRNAs
- Download full text (pdf) of The Human Adenovirus 2 Transcriptome: An Amazing Complexity of Alternatively Spliced mRNAs
Adenovirus VA RNAI Blocks ASC Oligomerization and Inhibits NLRP3 Inflammasome Activation
Part of Frontiers in Immunology, 2019
- DOI for Adenovirus VA RNAI Blocks ASC Oligomerization and Inhibits NLRP3 Inflammasome Activation
- Download full text (pdf) of Adenovirus VA RNAI Blocks ASC Oligomerization and Inhibits NLRP3 Inflammasome Activation
Multiple nuclear-replicating viruses require the stress-induced protein ZC3H11A for efficient growth
Part of Proceedings of the National Academy of Sciences of the United States of America, 2018
Part of PLOS ONE, 2017
- DOI for Expression profile of Epstein-Barr virus and human adenovirus small RNAs in tonsillar B and T lymphocytes
- Download full text (pdf) of Expression profile of Epstein-Barr virus and human adenovirus small RNAs in tonsillar B and T lymphocytes
An Ago2-associated capped transcriptional start site small RNA suppresses adenovirus DNA replication
Part of RNA, p. 1700-1711, 2017
- DOI for An Ago2-associated capped transcriptional start site small RNA suppresses adenovirus DNA replication
- Download full text (pdf) of An Ago2-associated capped transcriptional start site small RNA suppresses adenovirus DNA replication
Part of Nucleic Acids Research, p. 1731-1742, 2017
- DOI for The adenovirus L4-22K protein regulates transcription and RNA splicing via a sequence-specific single-stranded RNA binding
- Download full text (pdf) of The adenovirus L4-22K protein regulates transcription and RNA splicing via a sequence-specific single-stranded RNA binding
Part of Virology, p. 44-50, 2016
Part of PLOS ONE, 2016
- DOI for Distribution and Molecular Characterization of Human Adenovirus and Epstein-Barr Virus Infections in Tonsillar Lymphocytes Isolated from Patients Diagnosed with Tonsillar Diseases
- Download full text (pdf) of Distribution and Molecular Characterization of Human Adenovirus and Epstein-Barr Virus Infections in Tonsillar Lymphocytes Isolated from Patients Diagnosed with Tonsillar Diseases
Efficient Isolation Protocol for B and T Lymphocytes from Human Palatine Tonsils
Part of Journal of Visualized Experiments, 2015
Part of Virus Research, p. 133-140, 2015
Part of Virology, p. 120-128, 2015
Part of FEBS Letters, p. 1383-1388, 2015
Part of Virology, p. 25-35, 2015
Part of PLOS ONE, 2014
- DOI for Small RNA Sequence Analysis of Adenovirus VA RNA-Derived MiRNAs Reveals an Unexpected Serotype-Specific Difference in Structure and Abundance
- Download full text (pdf) of Small RNA Sequence Analysis of Adenovirus VA RNA-Derived MiRNAs Reveals an Unexpected Serotype-Specific Difference in Structure and Abundance
A mouse mammary epithelial cell line permissive for highly efficient human adenovirus growth
Part of Virology, p. 363-371, 2013
Part of Nucleic Acids Research, p. 4802-4812, 2013
- DOI for The adenovirus VA RNA-derived miRNAs are not essential for lytic virus growth in tissue culture cells
- Download full text (pdf) of The adenovirus VA RNA-derived miRNAs are not essential for lytic virus growth in tissue culture cells
Part of PLOS ONE, 2012
- DOI for Two Cellular Protein Kinases, DNA-PK and PKA, Phosphorylate the Adenoviral L4-33K Protein and Have Opposite Effects on L1 Alternative RNA Splicing
- Download full text (pdf) of Two Cellular Protein Kinases, DNA-PK and PKA, Phosphorylate the Adenoviral L4-33K Protein and Have Opposite Effects on L1 Alternative RNA Splicing
Part of Virology, p. 273-281, 2012
Using the whole-genome sequence to characterize and name human adenoviruses
Part of Journal of Virology, p. 5701-5702, 2011
Part of Genes & cancer, p. 841-851, 2011
Single molecule analysis of combinatorial splicing
Part of Nucleic Acids Research, 2010
Part of Virus Research, p. 220-228, 2010
Part of Cancer Research, p. 7431-7441, 2010
Adenovirus E4orf4 induces HPV-16 late L1 mRNA production
Part of Virology, p. 279-290, 2009
Part of Nucleic Acids Research, p. 6950-6959, 2009
Part of Biochemical and Biophysical Research Communications - BBRC, p. 517-521, 2008
Glucose-induced cyclic AMP oscillations regulate pulsatile insulin secretion
Part of Cell Metabolism, p. 26-37, 2008
- DOI for Glucose-induced cyclic AMP oscillations regulate pulsatile insulin secretion
- Download full text (pdf) of Glucose-induced cyclic AMP oscillations regulate pulsatile insulin secretion
Temporal regulation of adenovirus major late alternative RNA splicing
Part of Frontiers in Bioscience, p. 5006-5015, 2008
Part of Journal of Virology, p. 10540-10549, 2007
Involvement of the catalytic subunit of protein kinase A and of HA95 in pre-mRNA splicing
Part of Experimental Cell Research, p. 2795-2809, 2007
Part of Journal of Virology, p. 5010-5020, 2006
L4-33K, an adenovirus-encoded alternative RNA splicing factor
Part of Journal of Biological Chemistry, p. 36510-36517, 2006
Part of Virus research, p. 16-23, 2006
Part of Virus Res, p. 16-23, 2006
Suppression of RNA interference by adenovirus virus-associated RNA
Part of Journal of Virology, p. 9556-65, 2005
Part of Endocrinology, p. 2406-2414, 2005
Part of J Biol Chem, p. 25478-84, 2005
Part of Journal of General Virology, p. 185-196, 2004
Part of Biochem J, p. 343-50, 2004
Remodelling of the host cell RNA splicing machinery during an adenovirusinfection
Part of Current Topics in Microbiology and Immunology, p. 253-286, 2003
Part of FEBS Letters, p. 214-218, 2003
Part of FEBS Letters, p. 214-218, 2003
Adenoviral-induced islet cell cytotoxicity is not counteracted by Bcl-2 overexpression
Part of Molecular Medicine, p. 733-741, 2002
Part of Journal of Biological Chemistry, p. 12579-12586, 2002
Part of Virus Research, p. 197-206, 2002
Functional inactivation of the SR family of splicing factors during a vaccinia virus infection
Part of EMBO Reports, p. 1088-1093, 2002
Part of The Journal of Biological Chemistry, p. 12579-12586, 2002
Cisplatin induces the proapoptotic conformation of Bak in a deltaMEKK1-dependent manner
Part of Molecular and Cellular Biology, p. 3684-3691, 2001
Adenovirus vector designed for expression of toxic proteins
Part of Journal of Virology, p. 9579-9584, 2001
Part of EMBO Journal, p. 864-871, 2001
A novel type of splicing enhancer regulating adenovirus pre-mRNA splicing
Part of Molecular and Cellular Biology, p. 2317-2325, 2000
Part of Apoptosis (London), p. 355-367, 2000
Part of Cell growth & differentiation, p. 373-384, 2000
Part of Journal of Virology, p. 9002-9009, 2000
The adenovirus-2 E1B-55K protein interacts with a mSin3A/histone deacetylase 1 complex
Part of FEBS Letters, p. 248-252, 2000
Functional coexpression of serine protein kinase SRPK1 and its substrateASF/SF2 in Escherichia coli
Part of Nucleic Acids Research, 2000
The adenovirus-2 E1B-55K protein interacts with a mSin3A/histone deacetylase 1 complex.
Part of FEBS Letters, p. 248-252, 2000
Part of Virology, p. 313-321, 1999
A downstream splicing enhancer is essential for in vitro pre-mRNA splicing
Part of FEBS Letters, p. 10-14, 1999
Part of EMBO Journal, p. 1014-1024, 1999
Part of EMBO Journal, p. 1014-1024, 1999
Part of Journal of Virology, p. 8358-8861, 1998
AR1 is an integral part of the adenovirus-2 E1A CR3 transactivation domain
Part of Journal of Virology, p. 5978-5983, 1998
Regulation of adenovirus alternative RNAsplicing by dephosphorylation of SR proteins
Part of Nature, p. 185-187, 1998
Part of Journal of Virology, p. 8358-8361, 1998
Regulation of adenovirus alternative RNA splicing by dephosphorylation of SR proteins
Part of Nature, p. 185-187, 1998
Part of FEBS Letters, p. 111-116, 1997
Part of Journal of Virology, p. 3844-6851, 1996
Inhibition by SRproteins of splicing of a regulated adenovirus pre-mRNA
Part of Nature, p. 535-538, 1996
Targeting of adenovirus E1A and E4-ORF3 proteins to nuclear matrix-associated PML bodies
Part of Journal of Cell Biology, p. 45-56, 1995
Enhanced splicing of nonconsensus 3' splice sites late during adenovirus infection
Part of Journal of Virology, p. 7324-7327, 1995
Part of Nucleic Acids Symposium Series, p. 220-223, 1995
Articles, review/survey
Synthesis, Structure, and Function of Human Adenovirus Small Non-Coding RNAs
Part of Viruses, 2020
- DOI for Synthesis, Structure, and Function of Human Adenovirus Small Non-Coding RNAs
- Download full text (pdf) of Synthesis, Structure, and Function of Human Adenovirus Small Non-Coding RNAs
Role of CCCH-Type Zinc Finger Proteins in Human Adenovirus Infections
Part of Viruses, 2020
- DOI for Role of CCCH-Type Zinc Finger Proteins in Human Adenovirus Infections
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Regulation of Human Adenovirus Alternative RNA Splicing by the Adenoviral L4-33K and L4-22K Proteins
Part of International Journal of Molecular Sciences, p. 2893-2912, 2015
- DOI for Regulation of Human Adenovirus Alternative RNA Splicing by the Adenoviral L4-33K and L4-22K Proteins
- Download full text (pdf) of Regulation of Human Adenovirus Alternative RNA Splicing by the Adenoviral L4-33K and L4-22K Proteins
Old and new functions for the adenovirus virus-associated RNAs
Part of Future Virology, p. 343-356, 2013
Characterization of RISC-associated adenoviral small RNAs
Part of Methods in molecular biology (Clifton, N.J.), p. 183-198, 2011
Chapters in book
Regulation of adenovirus alternative RNA splicing by PKA, DNA-PK, PP2A and SR proteins
Part of Virology II: Advanced Issues, iConcept Press, 2014
Part of Encyclopedia of Life Sciences, p. 1-8, John Wiley, 2007
In vitro methods to study RNA interference during an adenovirus infection
Part of Adenovirus Methods and Protocols: Volume 2: Ad Proteins, RNA Lifecycle, Host Interactions, and Phylogenetics, p. 47-61, Humana Press Inc, Totowa, NJ, 2007
Preparation of soluble extracts from adenovirus-infected cells for studies of RNA-splicing
Part of Adenovirus Methods and Protocols, p. 33-46, Springer, 2007
Preparation of Soluble Extracts From Adenovirus-Infected Cells for Studies of RNA Spicing
Part of Adenovirus Methods and Protocols, p. 33-46, Humana Press Inc, Totowa, NJ, 2007
Part of Encyclopedia of Life Sciences, Nature Publishing, 2002
Part of The Encyclopedia of Physical Science and Technology, p. 501-517, Academic Press, San Diego, 2000
Remodelling of the host cell RNA splicing machinery during an adenovirus infection
Part of Recent research developments in Virology, p. 621, Transworld Research Network, 1999
Preparation of splicing competent nuclear extracts from adenovirus infected cells
Part of Adenovirus Methods and Protocols, p. 203-216, Humana Press Inc, 1998
Part of Clinical Virology, ChurchillLivingstone Inc, 1997
Gene expression, regulation of
Part of Encyclopedia of molecular biology and Molecular Medicine, p. 364-375, VCHPublishers, New York., 1996
Gene expression, regulation of
Part of The Encyclopedia of Molecular Biology and Biotechnology, p. 346, VCH Publishers, New York., 1995
Regulation of adenovirus alternative RNA splicing by PKA, DNA-PK, PP2A and SR proteins