Lena Claesson-Welsh

Vascular leakage in non-small cell lung cancer is associated with immune evasion and poor response to immunotherapy

Nwadozi, Emmanuel; Strell, Carina; Nordling, Sofia; Lindberg, Amanda et al.

Part of Cancer Letters, 2026

• DOI for Vascular leakage in non-small cell lung cancer is associated with immune evasion and poor response to immunotherapy
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Endothelial VEGFR2 insufficiency promotes the transition of lymphatic to hematopoietic transcriptional programs

Li, Taotao; Cao, Xudong; Zhou, Fei; Li, Xiujuan et al.

Part of Angiogenesis, 2026

• DOI for Endothelial VEGFR2 insufficiency promotes the transition of lymphatic to hematopoietic transcriptional programs

Neuropilin-1 controls vascular permeability through juxtacrine regulation of endothelial adherens junctions

Pal, Sagnik; Su, Yangyang; Nwadozi, Emmanuel; Claesson-Welsh, Lena et al.

Part of Angiogenesis, 2025

• DOI for Neuropilin-1 controls vascular permeability through juxtacrine regulation of endothelial adherens junctions
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TMEM16F scramblase regulates angiogenesis via endothelial intracellular signaling

Shan, Ke Zoe; Le, Trieu; Liang, Pengfei; Dong, Ping et al.

Part of Journal of Cell Science, 2024

• DOI for TMEM16F scramblase regulates angiogenesis via endothelial intracellular signaling

Hypersensitive blood vessels in Clarkson disease

Nwadozi, Emmanuel; Claesson-Welsh, Lena

Part of Journal of Clinical Investigation, 2024

• DOI for Hypersensitive blood vessels in Clarkson disease
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Vascular leakage in non-small cell lung cancer is associated with immune evasion and poor response to immunotherapy

Nwadozi, Emmanuel; Strell, Carina; Nordling, Sofia; Lindberg, Amanda et al.

Part of Cancer Letters, 2026

• DOI for Vascular leakage in non-small cell lung cancer is associated with immune evasion and poor response to immunotherapy
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Endothelial VEGFR2 insufficiency promotes the transition of lymphatic to hematopoietic transcriptional programs

Li, Taotao; Cao, Xudong; Zhou, Fei; Li, Xiujuan et al.

Part of Angiogenesis, 2026

• DOI for Endothelial VEGFR2 insufficiency promotes the transition of lymphatic to hematopoietic transcriptional programs

Neuropilin-1 controls vascular permeability through juxtacrine regulation of endothelial adherens junctions

Pal, Sagnik; Su, Yangyang; Nwadozi, Emmanuel; Claesson-Welsh, Lena et al.

Part of Angiogenesis, 2025

• DOI for Neuropilin-1 controls vascular permeability through juxtacrine regulation of endothelial adherens junctions
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TMEM16F scramblase regulates angiogenesis via endothelial intracellular signaling

Shan, Ke Zoe; Le, Trieu; Liang, Pengfei; Dong, Ping et al.

Part of Journal of Cell Science, 2024

• DOI for TMEM16F scramblase regulates angiogenesis via endothelial intracellular signaling

Hypersensitive blood vessels in Clarkson disease

Nwadozi, Emmanuel; Claesson-Welsh, Lena

Part of Journal of Clinical Investigation, 2024

• DOI for Hypersensitive blood vessels in Clarkson disease
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VE-cadherin junction dynamics in initial lymphatic vessels promotes lymph node metastasis

Sáinz-Jaspeado, Miguel; Ring, Sarah; Proulx, Steven T.; Richards, Mark et al.

Part of Life Science Alliance, 2024

• DOI for VE-cadherin junction dynamics in initial lymphatic vessels promotes lymph node metastasis
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Report from the 2023 workshop on endothelial permeability, edema and inflammation

Vestweber, Dietmar; Claesson-Welsh, Lena; McDonald, Donald M.; Williams, Timothy et al.

Part of Nature Cardiovascular Research, p. 1120-1124, 2023

• DOI for Report from the 2023 workshop on endothelial permeability, edema and inflammation

Endothelial VEGFR2-PLCγ signaling regulates vascular permeability and antitumor immunity through eNOS/Src

Sjöberg, Elin; Melssen, Marit; Richards, Mark; Ding, Yindi et al.

Part of Journal of Clinical Investigation, 2023

• DOI for Endothelial VEGFR2-PLCγ signaling regulates vascular permeability and antitumor immunity through eNOS/Src
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Chylomicrons Regulate Lacteal Permeability and Intestinal Lipid Absorption

Zarkada, Georgia; Chen, Xun; Zhou, Xuetong; Lange, Martin et al.

Part of Circulation Research, p. 333-349, 2023

• DOI for Chylomicrons Regulate Lacteal Permeability and Intestinal Lipid Absorption

CD93 maintains endothelial barrier function by limiting the phosphorylation and turnover of VE-cadherin

Lugano, Roberta; Vemuri, Kalyani; Barbera, Stefano; Orlandini, Maurizio et al.

Part of The FASEB Journal, 2023

• DOI for CD93 maintains endothelial barrier function by limiting the phosphorylation and turnover of VE-cadherin
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Tyrosine-protein kinase Yes is essential in vascular barrier dynamics

Claesson-Welsh, Lena; Jin, Yi

Part of Nature Cardiovascular Research, p. 1136-1137, 2022

• DOI for Tyrosine-protein kinase Yes is essential in vascular barrier dynamics

Targeting VEGF-induced vascular permeability

Richards, Mark; Claesson-Welsh, Lena

Part of Nature Cardiovascular Research, p. 413-414, 2022

• DOI for Targeting VEGF-induced vascular permeability

Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis

Jin, Yi; Ding, Yindi; Richards, Mark; Kaakinen, Mika et al.

Part of Nature Cardiovascular Research, p. 1156-1173, 2022

• DOI for Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis
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Claudin5 protects the peripheral endothelial barrier in an organ and vessel-type-specific manner

Richards, Mark; Nwadozi, Emmanuel; Pal, Sagnik; Martinsson, Pernilla et al.

Part of eLIFE, 2022

• DOI for Claudin5 protects the peripheral endothelial barrier in an organ and vessel-type-specific manner
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Targeting VEGF-A/VEGFR2 Y949 Signaling-Mediated Vascular Permeability Alleviates Hypoxic Pulmonary Hypertension

Zhou, Weibin; Liu, Keli; Zeng, Lei; He, Jiaqi et al.

Part of Circulation, p. 1855-1881, 2022

• DOI for Targeting VEGF-A/VEGFR2 Y949 Signaling-Mediated Vascular Permeability Alleviates Hypoxic Pulmonary Hypertension

Endothelial Unc5B controls blood-brain barrier integrity

Boye, Kevin; Geraldo, Luiz Henrique; Furtado, Jessica; Pibouin-Fragner, Laurence et al.

Part of Nature Communications, 2022

• DOI for Endothelial Unc5B controls blood-brain barrier integrity
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p73 is required for vessel integrity controlling endothelial junctional dynamics through Angiomotin

Maeso-Alonso, Laura; Alonso-Olivares, Hugo; Martinez-Garcia, Nicole; Lopez-Ferreras, Lorena et al.

Part of Cellular and Molecular Life Sciences (CMLS), 2022

• DOI for p73 is required for vessel integrity controlling endothelial junctional dynamics through Angiomotin
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Quartz Crystal Microbalance Measurement of Histidine-Rich Glycoprotein and Stanniocalcin-2 Binding to Each Other and to Inflammatory Cells

Persson Skare, Tor; Kaito, Hiroshi; Durall, Claudia; Aastrup, Teodor et al.

Part of Cells, 2022

• DOI for Quartz Crystal Microbalance Measurement of Histidine-Rich Glycoprotein and Stanniocalcin-2 Binding to Each Other and to Inflammatory Cells
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Intra-vessel heterogeneity establishes enhanced sites of macromolecular leakage downstream of laminin alpha 5

Richards, Mark; Pal, Sagnik; Sjöberg, Elin; Martinsson, Pernilla et al.

Part of Cell Reports, 2021

• DOI for Intra-vessel heterogeneity establishes enhanced sites of macromolecular leakage downstream of laminin alpha 5

Endothelial Cell Orientation and Polarity Are Controlled by Shear Stress and VEGF Through Distinct Signaling Pathways

Vion, Anne-Clemence; Perovic, Tijana; Petit, Charlie; Hollfinger, Irene et al.

Part of Frontiers in Physiology, 2021

• DOI for Endothelial Cell Orientation and Polarity Are Controlled by Shear Stress and VEGF Through Distinct Signaling Pathways
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Palmdelphin Regulates Nuclear Resilience to Mechanical Stress in the Endothelium

Sainz-Jaspeado, Miguel; Smith, Ross O.; Plunde, Oscar; Pawelzik, Sven-Christian et al.

Part of Circulation, p. 1629-1645, 2021

• DOI for Palmdelphin Regulates Nuclear Resilience to Mechanical Stress in the Endothelium
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Stories in Molecular Medicine April 2021

Kavelaars, Annemieke; Claesson-Welsh, Lena; Culp-Hill, Rachel; Lothstein, Katherine et al.

Part of Trends in Molecular Medicine, p. 293-296, 2021

• DOI for Stories in Molecular Medicine April 2021

eNOS-induced vascular barrier disruption in retinopathy by c-Src activation and tyrosine phosphorylation of VE-cadherin

Ninchoji, Takeshi; Love, Dominic T.; Smith, Ross O.; Hedlund, Marie et al.

Part of eLIFE, 2021

• DOI for eNOS-induced vascular barrier disruption in retinopathy by c-Src activation and tyrosine phosphorylation of VE-cadherin
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Paladin is a phosphoinositide phosphatase regulating endosomal VEGFR2 signalling and angiogenesis

Nitzsche, Anja; Pietilä, Riikka; Love, Dominic T.; Testini, Chiara et al.

Part of EMBO Reports, 2021

• DOI for Paladin is a phosphoinositide phosphatase regulating endosomal VEGFR2 signalling and angiogenesis
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Marginal zone lymphoma expression of histidine-rich glycoprotein correlates with improved survival

Persson Skare, Tor; Sjöberg, Elin; Berglund, Mattias; Smith, Ross O. et al.

Part of eJHaem, p. 199-207, 2020

• DOI for Marginal zone lymphoma expression of histidine-rich glycoprotein correlates with improved survival
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Suppressed Vascular Leakage and Myocardial Edema Improve Outcome From Myocardial Infarction

Li, Xiujuan; Redfors, Bjorn; Sainz-Jaspeado, Miguel; Shi, Shujing et al.

Part of Frontiers in Physiology, 2020

• DOI for Suppressed Vascular Leakage and Myocardial Edema Improve Outcome From Myocardial Infarction
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c-Src controls stability of sprouting blood vessels in the developing retina independently of cell-cell adhesion through focal adhesion assembly

Schimmel, Lilian; Fukuhara, Daisuke; Richards, Mark; Jin, Yi et al.

Part of Development, 2020

• DOI for c-Src controls stability of sprouting blood vessels in the developing retina independently of cell-cell adhesion through focal adhesion assembly
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Perivascular Neuropilin-1 expression is an independent marker of improved survival in renal cell carcinoma

Morin, Eric; Lindskog, Cecilia; Johansson, Martin; Egevad, Lars et al.

Part of Journal of Pathology, p. 387-396, 2020

• DOI for Perivascular Neuropilin-1 expression is an independent marker of improved survival in renal cell carcinoma
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How the matrix metalloproteinase MMP14 contributes to the progression of colorectal cancer: Comment

Claesson-Welsh, Lena

Part of Journal of Clinical Investigation, p. 1093-1095, 2020

• DOI for How the matrix metalloproteinase MMP14 contributes to the progression of colorectal cancer: Comment

Vascular permeability in retinopathy is regulated by VEGFR2 Y949 signaling to VE-cadherin

Smith, Ross O.; Ninchoji, Takeshi; Gordon, Emma; Andre, Helder et al.

Part of eLIFE, 2020

• DOI for Vascular permeability in retinopathy is regulated by VEGFR2 Y949 signaling to VE-cadherin
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House retinal cell behaviour in space and time using light sheet fluorescence microscopy

Prahst, Claudia; Ashrafzadeh, Parham; Mead, Thomas; Figueiredo, Ana et al.

Part of eLIFE, 2020

• DOI for House retinal cell behaviour in space and time using light sheet fluorescence microscopy
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Sphingosine-1-Phosphate Receptor 1 Activity Promotes Tumor Growth by Amplifying VEGF-VEGFR2 Angiogenic Signaling

Ragunathrao, Vijay Avin Balaji; Anwar, Mumtaz; Akhter, Md Zahid; Chavez, Alejandra et al.

Part of Cell Reports, p. 3472-3487, 2019

• DOI for Sphingosine-1-Phosphate Receptor 1 Activity Promotes Tumor Growth by Amplifying VEGF-VEGFR2 Angiogenic Signaling
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ATTRACT Arterial Flow as Attractor for Endothelial Cell Migration

Georgieva, Petya B.; Marchuk, Douglas A.; Gerhardt, Holger; Franco, Claudio A. et al.

Part of Circulation Research, p. 262-264, 2019

• DOI for ATTRACT Arterial Flow as Attractor for Endothelial Cell Migration

What is normal?: Apelin and VEGFA, drivers of tumor vessel abnormality

Claesson-Welsh, Lena

Part of EMBO Molecular Medicine, 2019

• DOI for What is normal?: Apelin and VEGFA, drivers of tumor vessel abnormality
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Myc-dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor-2

Testini, Chiara; Smith, Ross O.; Jin, Yi; Martinsson, Pernilla et al.

Part of EMBO Reports, 2019

• DOI for Myc-dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor-2
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Temporal Dynamics of VEGFA-Induced VEGFR2/FAK Co-Localization Depend on SHB

Pietilä, Ilkka; van Mourik, Djenolan; Tamelander, Andreas; Kriz, Vitezslav et al.

Part of Cells, 2019

• DOI for Temporal Dynamics of VEGFA-Induced VEGFR2/FAK Co-Localization Depend on SHB
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Caspase-8 modulates physiological and pathological angiogenesis during retina development

Tisch, Nathalie; Freire-Valls, Aida; Yerbes, Rosario; Paredes, Isidora et al.

Part of Journal of Clinical Investigation, p. 5092-5107, 2019

• DOI for Caspase-8 modulates physiological and pathological angiogenesis during retina development

Fine-Tuning of Sox17 and Canonical Wnt Coordinates the Permeability Properties of the Blood-Brain Barrier

Corada, Monica; Orsenigo, Fabrizio; Bhat, Ganesh Parameshwar; Conze, Lei Liu et al.

Part of Circulation Research, p. 511-525, 2019

• DOI for Fine-Tuning of Sox17 and Canonical Wnt Coordinates the Permeability Properties of the Blood-Brain Barrier
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U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.

Glimelius, Bengt; Melin, Beatrice; Enblad, Gunilla; Alafuzoff, Irina et al.

Part of Acta Oncologica, p. 187-194, 2018

• DOI for U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.
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Shear stress, notch and VE-cadherin: the molecular mechanism of vascular fusion

Caolo, V.; Peacock, H. M.; Kasaai, B.; Swennen, G. et al.

Part of Cardiovascular Research, 2018

Alk1 (Activin Receptor-Like Kinase 1) and Vascular Hyperpermeability in Diabetic Retinopathy: More Is Less

Claesson-Welsh, Lena

Part of Arteriosclerosis, Thrombosis and Vascular Biology, p. 1673-1675, 2018

• DOI for Alk1 (Activin Receptor-Like Kinase 1) and Vascular Hyperpermeability in Diabetic Retinopathy: More Is Less

Shear Stress and VE-Cadherin: The Molecular Mechanism of Vascular Fusion

Caolo, Vincenza; Peacock, Hanna M.; Kasaai, Bahar; Swennen, Geertje et al.

Part of Arteriosclerosis, Thrombosis and Vascular Biology, p. 2174-2183, 2018

• DOI for Shear Stress and VE-Cadherin: The Molecular Mechanism of Vascular Fusion

Radionuclide imaging of VEGFR2 in glioma vasculature using biparatopic affibody conjugate: proof-of-principle in a murine model

Mitran, Bogdan; Güler, Rezan; Roche, Francis P.; Lindström, Elin et al.

Part of Theranostics, p. 4462-4476, 2018

• DOI for Radionuclide imaging of VEGFR2 in glioma vasculature using biparatopic affibody conjugate: proof-of-principle in a murine model
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Intravital imaging-based analysis tools for vessel identification and assessment of concurrent dynamic vascular events

Honkura, Naoki; Richards, Mark; Laviña, Bàrbara; Sainz-Jaspeado, Miguel et al.

Part of Nature Communications, 2018

• DOI for Intravital imaging-based analysis tools for vessel identification and assessment of concurrent dynamic vascular events
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VEGF receptor-2/neuropilin 1 trans-complex formation between endothelial and tumor cells is an independent predictor of pancreatic cancer survival

Morin, Eric; Sjöberg, Elin; Tjomsland, Vegard; Testini, Chiara et al.

Part of Journal of Pathology, p. 311-322, 2018

• DOI for VEGF receptor-2/neuropilin 1 trans-complex formation between endothelial and tumor cells is an independent predictor of pancreatic cancer survival
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Leukocyte differentiation by histidine-rich glycoprotein/stanniocalcin-2 complex regulates murine glioma growth through modulation of anti-tumor immunity

Roche, Francis P.; Pietilä, Ilkka; Kaito, Hiroshi; Sjöström, Elisabet O. et al.

Part of Molecular Cancer Therapeutics, p. 1961-1972, 2018

• DOI for Leukocyte differentiation by histidine-rich glycoprotein/stanniocalcin-2 complex regulates murine glioma growth through modulation of anti-tumor immunity
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Highly sensitive and specific protein detection via combined capillary isoelectric focusing and proximity ligation

Padhan, Narendra; Yan, Junhong; Boge, Annegret; Scrivener, Elaine et al.

Part of Scientific Reports, 2017

• DOI for Highly sensitive and specific protein detection via combined capillary isoelectric focusing and proximity ligation
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Novel high affinity affibody for radionuclide imaging of VEGFR2 in glioma vasculature: proof-of-principle in murine model

Mitran, Bogdan; Guler, R.; Roche, Francis P.; Lindström, Elin et al.

Part of European Journal of Nuclear Medicine and Molecular Imaging, 2017

Case-specific potentiation of glioblastoma drugs by pterostilbene

Schmidt, Linnéa; Baskaran, Sathishkumar; Johansson, Patrik; Padhan, Narendra et al.

Part of Oncotarget, p. 73200-73215, 2016

• DOI for Case-specific potentiation of glioblastoma drugs by pterostilbene

High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer

Padhan, Narendra; Nordling, Torbjorn E. M.; Sundström, Magnus; Åkerud, Peter et al.

Part of BMC Cancer, 2016

• DOI for High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer
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VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread

Li, Xiujuan; Padhan, Narendra; Sjöström, Elisabet O.; Roche, Francis P. et al.

Part of Nature Communications, 2016

• DOI for VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread
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The endothelial adaptor molecule TSAd is required for VEGF-induced angiogenic sprouting through junctional c-Src activation

Gordon, Emma J.; Fukuhara, Daisuke; Weström, Simone; Padhan, Narendra et al.

Part of Science Signaling, 2016

• DOI for The endothelial adaptor molecule TSAd is required for VEGF-induced angiogenic sprouting through junctional c-Src activation

Tracheobronchial transplantation: The Royal Swedish Academy of Sciences' concerns

Claesson-Welsh, Lena; Hansson, Goran K.

Part of The Lancet, p. 942-942, 2016

• DOI for Tracheobronchial transplantation: The Royal Swedish Academy of Sciences' concerns

Novel affinity binders for neutralization of vascular endothelial growth factor (VEGF) signaling

Fleetwood, Filippa; Guler, Rezan; Gordon, Emma; Stahl, Stefan et al.

Part of Cellular and Molecular Life Sciences (CMLS), p. 1671-1683, 2016

• DOI for Novel affinity binders for neutralization of vascular endothelial growth factor (VEGF) signaling

Identification and characterization of VEGF-A-responsive neutrophils expressing CD49d, VEGFR1, and CXCR4 in mice and humans

Massena, Sara; Christoffersson, Gustaf; Vågesjö, Evelina; Seignez, Cédric et al.

Part of Blood, p. 2016-2026, 2015

• DOI for Identification and characterization of VEGF-A-responsive neutrophils expressing CD49d, VEGFR1, and CXCR4 in mice and humans

New Frontiers in VEGF/VEGFR Biology

Claesson-Welsh, Lena

Part of Journal of Vascular Research, p. 79-79, 2015

Histidine-rich glycoprotein blocks collagen-binding integrins and adhesion of endothelial cells through low-affinity interaction with alpha 2 integrin

Roche, Francis; Sipilä, Kalle; Honjo, Satoshi; Staffan, Johansson et al.

Part of Matrix Biology, p. 89-99, 2015

• DOI for Histidine-rich glycoprotein blocks collagen-binding integrins and adhesion of endothelial cells through low-affinity interaction with alpha 2 integrin

p73 is required for endothelial cell differentiation, migration and the formation of vascular networks regulating VEGF and TGF beta signaling

Fernandez-Alonso, R.; Martin-Lopez, M.; Gonzalez-Cano, L.; Garcia, S. et al.

Part of Cell Death and Differentiation, p. 1287-+, 2015

• DOI for p73 is required for endothelial cell differentiation, migration and the formation of vascular networks regulating VEGF and TGF beta signaling

On the physiology of vascular permeability

Claesson-Welsh, Lena

Part of Acta Physiologica, p. 19-19, 2015

Pulmonary Lymphangiectasia Resulting From Vascular Endothelial Growth Factor-C Overexpression During a Critical Period

Yao, Li-Chin; Testini, Chiara; Tvorogov, Denis; Anisimov, Andrey et al.

Part of Circulation Research, p. 806-822, 2014

• DOI for Pulmonary Lymphangiectasia Resulting From Vascular Endothelial Growth Factor-C Overexpression During a Critical Period

The role of differential VE-cadherin dynamics in cell rearrangement during angiogenesis

Bentley, Katie; Franco, Claudio Areias; Philippides, Andrew; Blanco, Raquel et al.

Part of Nature Cell Biology, p. 309-321, 2014

• DOI for The role of differential VE-cadherin dynamics in cell rearrangement during angiogenesis

NRP1 Presented in trans to the Endothelium Arrests VEGFR2 Endocytosis, Preventing Angiogenic Signaling and Tumor Initiation

Koch, Sina; van Meeteren, Laurens A.; Morin, Eric; Testini, Chiara et al.

Part of Developmental Cell, p. 633-646, 2014

• DOI for NRP1 Presented in trans to the Endothelium Arrests VEGFR2 Endocytosis, Preventing Angiogenic Signaling and Tumor Initiation

Histidine-Rich Glycoprotein Uptake and Turnover Is Mediated by Mononuclear Phagocytes.

Tugues, Sònia; Roche, Francis; Noguer, Oriol; Orlova, Anna et al.

Part of PLOS ONE, 2014

• DOI for Histidine-Rich Glycoprotein Uptake and Turnover Is Mediated by Mononuclear Phagocytes.
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Histidine-Rich Glycoprotein (HRG): A Novel Gene-Therapy Effector for the Treatment of Cancer

Roche, Francis P.; Ohlin, Elisabet K.; Essand, Magnus; Claesson-Welsh, Lena

Part of Molecular Therapy, 2014

VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation

Hayashi, Makoto; Majumdar, Arindam; Li, Xiujuan; Adler, Jeremy et al.

Part of Nature Communications, p. 1672, 2013

• DOI for VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation

Pulmunary Lymphangiectasia Resulting From Vascular Endotelial Growth Factor-C Overexpression During a Critical Period

Yao, Li-Chin; Testini, Chiara; Tvorogov, Denis; Anisimov, Andrey et al.

Part of Circulation Research, 2013

Hypoxia-Induced Arterial Differentiation Requires Adrenomedullin and Notch Signaling

Lanner, Fredrik; Lee, Kian Leong; Ortega, German C.; Sohl, Marcus et al.

Part of Stem Cells and Development, p. 1360-1369, 2013

• DOI for Hypoxia-Induced Arterial Differentiation Requires Adrenomedullin and Notch Signaling

The mechanisms of VEGF-A-induced recruitment of pro-angiogenic neutrophils

Massena, Sara; Christoffersson, Gustaf; Vågesjö, Evelina; Gustafsson, Karin et al.

Part of European Journal of Clinical Investigation, p. 27-27, 2013

Introduction to the ECR special angiogenesis issue

Claesson-Welsh, Lena; Gerhardt, Holger

Part of Experimental Cell Research, p. 1239-1239, 2013

• DOI for Introduction to the ECR special angiogenesis issue

Histidine-Rich Glycoprotein (HRG): A Novel Gene-Therapy Effector for the Treatment of Cancer

Roche, Francis P.; Ohlin, Elisabet; Essand, Magnus; Claesson-Welsh, Lena

Part of Molecular Therapy, 2013

Tetraspanin CD63 Promotes Vascular Endothelial Growth Factor Receptor 2-beta 1 Integrin Complex Formation, Thereby Regulating Activation and Downstream Signaling in Endothelial Cells in Vitro and in Vivo

Tugues, Sonia; Honjo, Satoshi; König, Christian; Padhan, Narendra et al.

Part of Journal of Biological Chemistry, p. 19060-19071, 2013

• DOI for Tetraspanin CD63 Promotes Vascular Endothelial Growth Factor Receptor 2-beta 1 Integrin Complex Formation, Thereby Regulating Activation and Downstream Signaling in Endothelial Cells in Vitro and in Vivo

Introduction to symposium on vascular biology, metabolism and cancer

Claesson-Welsh, Lena

Part of Journal of Internal Medicine, p. 112-113, 2013

• DOI for Introduction to symposium on vascular biology, metabolism and cancer

Signal transduction by vascular endothelial growth factor receptors

Koch, Sina; Claesson-Welsh, Lena

Part of Cold Spring Harbor Perspectives in Medicine, 2012

• DOI for Signal transduction by vascular endothelial growth factor receptors

Histidine-rich Glycoprotein Regulates Macrophage Differentiation

Noguer, Oriol; Tugues, Sonia; Honjo, Satoshi; Claesson-Welsh, Lena

Part of European Journal of Cancer, 2012

• DOI for Histidine-rich Glycoprotein Regulates Macrophage Differentiation

Functional Overlap Between Chondroitin and Heparan Sulfate Proteoglycans During VEGF-Induced Sprouting Angiogenesis

Le Jan, Sébastien; Hayashi, Makoto; Kasza, Zsolt; Eriksson, Inger et al.

Part of Arteriosclerosis, Thrombosis and Vascular Biology, p. 1255-1263, 2012

• DOI for Functional Overlap Between Chondroitin and Heparan Sulfate Proteoglycans During VEGF-Induced Sprouting Angiogenesis

Receptor Talk and Tumor Cell Walk in Glioblastoma

Claesson-Welsh, Lena

Part of Cancer Cell, p. 1-2, 2012

• DOI for Receptor Talk and Tumor Cell Walk in Glioblastoma

Genetic deficiency in plasma protein HRG enhances tumor growth and metastasis by exacerbating immune escape and vessel abnormalization

Tugues, Sònia; Honjo, Satoshi; König, Christian; Noguer, Oriol et al.

Part of Cancer Research, 2012

• DOI for Genetic deficiency in plasma protein HRG enhances tumor growth and metastasis by exacerbating immune escape and vessel abnormalization

VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd

Sun, Zuyue; Li, Xiujuan; Massena, Sara; Kutschera, Simone et al.

Part of Journal of Experimental Medicine, p. 1363-1377, 2012

• DOI for VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd

Signal transduction by vascular endothelial growth factor receptors

Claesson-Welsh, Lena

Part of Vascular pharmacology, p. 308-308, 2012

• DOI for Signal transduction by vascular endothelial growth factor receptors

Analysis of VEGF-A Regulated Gene Expression in Endothelial Cells to Identify Genes Linked to Angiogenesis

Rivera, Corban G.; Mellberg, Sofie; Claesson-Welsh, Lena; Bader, Joel S. et al.

Part of PLOS ONE, 2011

• DOI for Analysis of VEGF-A Regulated Gene Expression in Endothelial Cells to Identify Genes Linked to Angiogenesis

HRG Inhibits Tumor Growth and Metastasis by Inducing Macrophage Polarization and Vessel Normalization through Downregulation of PIGF

Rolny, Charlotte; Mazzone, Massimiliano; Tugues, Sònia; Laoui, Damya et al.

Part of Cancer Cell, p. 31-44, 2011

• DOI for HRG Inhibits Tumor Growth and Metastasis by Inducing Macrophage Polarization and Vessel Normalization through Downregulation of PIGF

VEGF-mediated signal transduction in lymphatic endothelial cells

Bahram, Fuad; Claesson-Welsh, Lena

Part of Pathophysiology : the official journal of the International Society for Pathophysiology / ISP, p. 253-261, 2010

• DOI for VEGF-mediated signal transduction in lymphatic endothelial cells

Further pharmacological and genetic evidence for the efficacy of PlGF inhibition in cancer and eye disease

Van de Veire, Sara; Stalmans, Ingeborg; Heindryckx, Femke; Oura, Hajimu et al.

Part of Cell, p. 178-190, 2010

• DOI for Further pharmacological and genetic evidence for the efficacy of PlGF inhibition in cancer and eye disease

Vascular endothelial growth factor B controls endothelial fatty acid uptake

Hagberg, Carolina E.; Falkevall, Annelie; Wang, Xun; Larsson, Erik et al.

Part of Nature, p. 917-921, 2010

• DOI for Vascular endothelial growth factor B controls endothelial fatty acid uptake

VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts

Nilsson, Ingrid; Bahram, Fuad; Li, Xiujuan; Gualandi, Laura et al.

Part of EMBO Journal, p. 1377-1388, 2010

• DOI for VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts

T cell specific adapter protein (TSAd) interacts with Tec kinase ITK to promote CXCL12 induced migration of human and murine T cells

Berge, Tone; Sundvold-Gjerstad, Vibeke; Granum, Stine; Andersen, Thorny C. et al.

Part of PloS one, 2010

• DOI for T cell specific adapter protein (TSAd) interacts with Tec kinase ITK to promote CXCL12 induced migration of human and murine T cells

Gremlin: vexing VEGF receptor agonist

Claesson-Welsh, Lena

Part of Blood, p. 3386-3387, 2010

• DOI for Gremlin: vexing VEGF receptor agonist

A mutated soluble neuropilin-2 B domain antagonizes vascular endothelial growth factor bioactivity and inhibits tumor progression

Geretti, Elena; van Meeteren, Laurens A.; Shimizu, Akio; Dudley, Andrew C. et al.

Part of Molecular Cancer Research, p. 1063-1073, 2010

• DOI for A mutated soluble neuropilin-2 B domain antagonizes vascular endothelial growth factor bioactivity and inhibits tumor progression

p21-activated kinase 4 phosphorylation of integrin beta5 Ser-759 and Ser-762 regulates cell migration

Li, Zhilun; Zhang, Hongquan; Lundin, Lars; Thullberg, Minna et al.

Part of Journal of Biological Chemistry, p. 23699-23710, 2010

• DOI for p21-activated kinase 4 phosphorylation of integrin beta5 Ser-759 and Ser-762 regulates cell migration

ADAM-mediated shedding, a new flavor in angiogenesis regulation

Claesson-Welsh, Lena

Part of Arteriosclerosis, Thrombosis and Vascular Biology, p. 2087-2088, 2010

• DOI for ADAM-mediated shedding, a new flavor in angiogenesis regulation

Transcriptional profiling reveals a critical role for tyrosine phosphatase VE-PTP in regulation of VEGFR2 activity and endothelial cell morphogenesis

Mellberg, Sofie; Dimberg, Anna; Bahram, Fuad; Hayashi, Makoto et al.

Part of The FASEB Journal, p. 1490-1502, 2009

• DOI for Transcriptional profiling reveals a critical role for tyrosine phosphatase VE-PTP in regulation of VEGFR2 activity and endothelial cell morphogenesis

Distinct role of PLC{beta}3 in VEGF-mediated directional migration and vascular sprouting

Bhattacharya, Resham; Kwon, Junhye; Li, Xiujuan; Wang, Enfeng et al.

Part of Journal of Cell Science, p. 1025-1034, 2009

• DOI for Distinct role of PLC{beta}3 in VEGF-mediated directional migration and vascular sprouting

Type 3 cystatins: fetuins, kininogen and histidine-rich glycoprotein

Lee, Chunsik; Bongcam-Rudloff, Erik; Sollner, Christian; Jahnen-Dechent, Willi et al.

Part of Frontiers in Bioscience, p. 2911-2922, 2009

• DOI for Type 3 cystatins: fetuins, kininogen and histidine-rich glycoprotein

Vascular basement membrane components in angiogenesis: an act of balance

Jakobsson, Lars; Claesson-Welsh, Lena

Part of Scientific World Journal, p. 1246-1249, 2008

• DOI for Vascular basement membrane components in angiogenesis: an act of balance

Laminin deposition is dispensable for vasculogenesis but regulates blood vessel diameter independent of flow

Jakobsson, Lars; Domogatskaya, Anna; Tryggvason, Karl; Edgar, David et al.

Part of The FASEB Journal, p. 1530-1539, 2008

• DOI for Laminin deposition is dispensable for vasculogenesis but regulates blood vessel diameter independent of flow

alphaB-crystallin promotes tumor angiogenesis by increasing vascular survival during tube morphogenesis

Dimberg, Anna; Rylova, Svetlana; Dieterich, Lothar C; Olsson, Anna-Karin et al.

Part of Blood, p. 2015-2023, 2008

• DOI for alphaB-crystallin promotes tumor angiogenesis by increasing vascular survival during tube morphogenesis

Neuropilin-1 in regulation of VEGF-induced activation of p38MAPK and endothelial cell organization

Kawamura, Harukiyo; Li, Xiujuan; Goishi, Katsutoshi; van Meeteren, Laurens A et al.

Part of Blood, p. 3638-49, 2008

• DOI for Neuropilin-1 in regulation of VEGF-induced activation of p38MAPK and endothelial cell organization

Ninein Is Expressed in the Cytoplasm of Angiogenic Tip-Cells and Regulates Tubular Morphogenesis of Endothelial Cells

Matsumoto, Taro; Schiller, Petter; Dietrich, Lothar C.; Bahram, Fuad et al.

Part of Arteriosclerosis, Thrombosis and Vascular Biology, p. 2123-2130, 2008

• DOI for Ninein Is Expressed in the Cytoplasm of Angiogenic Tip-Cells and Regulates Tubular Morphogenesis of Endothelial Cells

Healing hemangiomas

Claesson-Welsh, Lena

Part of Nature Medicine, p. 1147-8, 2008

• DOI for Healing hemangiomas

VEGF-B taken to our hearts: specific effect of VEGF-B in myocardial ischemia

Claesson-Welsh, Lena

Part of Arteriosclerosis, Thrombosis and Vascular Biology, p. 1575-6, 2008

• DOI for VEGF-B taken to our hearts: specific effect of VEGF-B in myocardial ischemia

Vascular endothelial growth factor (VEGF)-A165b is a weak in vitro agonist for VEGF receptor-2 due to lack of coreceptor binding and deficient regulation of kinase activity

Kawamura, Harukiyo; Li, Xiujuan; Harper, Steven J; Bates, David O et al.

Part of Cancer Research, p. 4683-4692, 2008

• DOI for Vascular endothelial growth factor (VEGF)-A165b is a weak in vitro agonist for VEGF receptor-2 due to lack of coreceptor binding and deficient regulation of kinase activity

Orf virus VEGF-E NZ2 promotes paracellular NRP-1/VEGFR-2 coreceptor assembly via the peptide RPPR

Cébe-Suarez, Stéphanie; Grünewald, Felix S.; Jaussi, Rolf; Li, Xiujuan et al.

Part of The FASEB Journal, p. 3078-3086, 2008

• DOI for Orf virus VEGF-E NZ2 promotes paracellular NRP-1/VEGFR-2 coreceptor assembly via the peptide RPPR

Platelet-derived growth factor receptor-beta constitutive activity promotes angiogenesis in vivo and in vitro

Magnusson, Peetra U.; Looman, Camilla; Åhgren, Aive; Wu, Yan et al.

Part of Arteriosclerosis, Thrombosis and Vascular Biology, p. 2142-2149, 2007

• DOI for Platelet-derived growth factor receptor-beta constitutive activity promotes angiogenesis in vivo and in vitro

FGFR-1 regulates angiogenesis through cytokines interleukin-4 and pleiotrophin

Magnusson, Peetra U; Dimberg, Anna; Mellberg, Sofie; Lukinius, Agneta et al.

Part of Blood, p. 4214-4222, 2007

• DOI for FGFR-1 regulates angiogenesis through cytokines interleukin-4 and pleiotrophin

Lentiviral rescue of vascular endothelial growth factor receptor-2 expression in flk1-/- embryonic stem cells shows early priming of endothelial precursors

Li, Xiujuan; Edholm, Dan; Lanner, Fredrik; Breier, Georg et al.

Part of Stem Cells, p. 2987-2995, 2007

• DOI for Lentiviral rescue of vascular endothelial growth factor receptor-2 expression in flk1-/- embryonic stem cells shows early priming of endothelial precursors

Angiomotin regulates endothelial cell migration during embryonic angiogenesis

Aase, Karin; Ernkvist, Mira; Ebarasi, Lwaki; Jakobsson, Lars et al.

Part of Genes & Development, p. 2055-2068, 2007

• DOI for Angiomotin regulates endothelial cell migration during embryonic angiogenesis

Early lymph vessel development from embryonic stem cells

Kreuger, Johan; Nilsson, Ingrid; Kerjaschki, Dontscho; Petrova, Tatiana et al.

Part of Arteriosclerosis, Thrombosis and Vascular Biology, p. 1073-1078, 2006

• DOI for Early lymph vessel development from embryonic stem cells

Minimal active domain and mechanism of action of the angiogenesis inhibitor histidine-rich glycoprotein

Dixelius, Johan; Olsson, Anna-Karin; Thulin, Åsa; Lee, Chunsik et al.

Part of Cancer Research, p. 2089-97, 2006

• DOI for Minimal active domain and mechanism of action of the angiogenesis inhibitor histidine-rich glycoprotein

Signal transduction in endothelial cells by the angiogenesis inhibitor histidine-rich glycoprotein targets focal adhesions

Lee, Chunsik; Dixelius, Johan; Thulin, Åsa; Kawamura, Harukiyo et al.

Part of Experimental Cell Research, p. 2547-2556, 2006

• DOI for Signal transduction in endothelial cells by the angiogenesis inhibitor histidine-rich glycoprotein targets focal adhesions

Platelet-derived growth factor receptor-beta promotes early endothelial cell differentiation

Rolny, Charlotte; Nilsson, Ingrid; Magnusson, Peetra; Armulik, Annika et al.

Part of Blood, p. 1877-1886, 2006

• DOI for Platelet-derived growth factor receptor-beta promotes early endothelial cell differentiation

VEGF receptor signalling: in control of vascular function

Olsson, Anna-Karin; Dimberg, Anna; Kreuger, Johan; Claesson-Welsh, Lena

Part of Nature reviews. Molecular cell biology, p. 359-371, 2006

• DOI for VEGF receptor signalling: in control of vascular function

Heparan sulfate in trans potentiates VEGFR-mediated angiogenesis

Jakobsson, Lars; Kreuger, Johan; Holmborn, Katarina; Lundin, Lars et al.

Part of Developmental Cell, p. 625-634, 2006

VEGF receptor-2 Y951 signaling and a role for the adapter molecule TSAd in tumor angiogenesis.

Matsumoto, Taro; Bohman, Svante; Dixelius, Johan; Berge, Tone et al.

Part of EMBO J, p. 2342-53, 2005

Fibroblast growth factor receptor-1 expression is required for hematopoietic but not endothelial cell development

Magnusson, Peetra Ulrica; Ronca, Roberto; Dell'Era, Patrizia; Carlstedt, Pia et al.

Part of Arteriosclerosis, Thrombosis and Vascular Biology, p. 944-949, 2005

• DOI for Fibroblast growth factor receptor-1 expression is required for hematopoietic but not endothelial cell development

Proteomic analysis of vascular endothelial growth factor-induced endothelial cell differentiation reveals a role for chloride intracellular channel 4 (CLIC4) in tubular morphogenesis.

Bohman, Svante; Matsumoto, Taro; Suh, Kwang; Dimberg, Anna et al.

Part of J Biol Chem, p. 42397-404, 2005

Vascular endothelial growth factor receptor-3 in hypoxia-induced vascular development

Nilsson, Ingrid; Rolny, Charlotte; Wu, Yan; Pytowski, Bronislaw et al.

Part of The FASEB Journal, p. 1507-15, 2004

• DOI for Vascular endothelial growth factor receptor-3 in hypoxia-induced vascular development

Deregulation of Flk-1/vascular endothelial growth factor receptor-2 in fibroblast growth factor receptor-1-deficient vascular stem cell development

Magnusson, Peetra; Rolny, Charlotte; Jakobsson, Lars; Wikner, Charlotte et al.

Part of Journal of Cell Science, p. 1513-1523, 2004

• DOI for Deregulation of Flk-1/vascular endothelial growth factor receptor-2 in fibroblast growth factor receptor-1-deficient vascular stem cell development

The minimal active domain of endostatin is a heparin-binding motif that mediates inhibition of tumor vascularization

Olsson, Anna-Karin; Johansson, Irja; Åkerud, Helena; Einarsson, Barbro et al.

Part of Cancer Research, p. 9012-9017, 2004

• DOI for The minimal active domain of endostatin is a heparin-binding motif that mediates inhibition of tumor vascularization

A fragment of histidine-rich glycoprotein is a potent inhibitor of tumor vascularization

Olsson, Anna-Karin; Larsson, Helena; Dixelius, Johan; Johansson, Irja et al.

Part of Cancer Research, p. 599-605, 2004

Angiogenesis in Synergy with Fibroblast Growth Factor by Distinct Regulation of the Gene and Protein. Expression Profile in Endothelial Cells.

Dixelius, J; Jakobsson, L; Genersch, E; Bohman, S et al.

Part of J Biol Chem, p. 23766, 2004

Translocated in liposarcoma (TLS) is a substrate for fibroblast growth factor receptor-1.

Klint, Peter; Hellman, Ulf; Wernstedt, Christer; Aman, Pierre et al.

Part of Cell Signal, p. 515-20, 2004

The adaptor protein Shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration.

Holmqvist, Kristina; Cross, Michael J; Rolny, Charlotte; Hägerkvist, Robert et al.

Part of J Biological chemistry, p. 22267-22275, 2004

Endostatin action and intracellular signaling: beta-catenin as a potential target?

Dixelius, J; Cross, MJ; Matsumoto, T; Claesson-Welsh, L

Part of Cancer Letters, p. 1, 2003

Ligand-induced vascular endothelial growth factor receptor-3 (VEGFR-3) heterodimerization with VEGFR-2 in primary lymphatic endothelial cells regulates tyrosine phosphorylation sites

Dixelius, Johan; Mäkinen, Taija; Wirzenius, Maria; Karkkainen, Marika J. et al.

Part of J Biol Chem, p. 40973, 2003

Differential tyrosine phosphorylation of fibroblast growth factor (FGF) receptor-1 and receptor proximal signal transduction in response to FGF-2 and heparin.

Lundin, Lars; Rönnstrand, Lars; Cross, Michael; Hellberg, Carina et al.

Part of Exp Cell Res, p. 190-8, 2003

A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2.

Qi, JH; Ebrahem, Q; Moore, N; Murphy, G et al.

Part of Nat Med., p. 407, 2003

[Islet of Langerhans transplantation in type I diabetes. Regulation of neovascularization in the transplant is a key question]

Claesson-Welsh, L

Part of Lakartidningen, p. 1210, 2003

Angiostatin and endostatin inhibit endothelial cell migration in response to FGF and VEGF without interfering with specific intracellular signal transduction pathways.

Eriksson, K; Magnusson, P; Dixelius, J; Claesson-Welsh, L et al.

Part of FEBS Lett., p. 19, 2003

Signal transduction by vascular endothelial growth factor receptors.

Claesson-Welsh, L

Part of Biochem Soc Trans, p. 20, 2003

VEGF-receptor signal transduction

Cross, MJ; Dixelius, J; Matsumoto, T; Claesson-Welsh, L

Part of Trends Biochem Sci, p. 488, 2003

p38 MAP kinase negatively regulates endothelial cell survival, proliferation, and differentiation in FGF-2-stimulated angiogenesis

Matsumoto, Taro; Turesson, Ingela; Book, Majlis; Gerwins, Pär et al.

Part of Journal of Cell Biology, p. 149-160, 2002

• DOI for p38 MAP kinase negatively regulates endothelial cell survival, proliferation, and differentiation in FGF-2-stimulated angiogenesis

The Shb Adaptor Protein Binds to Tyrosine 766 in the FGFR-1 and Regulatesthe Ras/MEK/MAPK Pathway via FRS2 Phosphorylation in Endothelial Cells

Cross, Michael J; Lu, Lingge; Magnusson, Peetra; Nyqvist, Daniel et al.

Part of Molecular Biology of the Cell, p. 2881-2893, 2002

• DOI for The Shb Adaptor Protein Binds to Tyrosine 766 in the FGFR-1 and Regulatesthe Ras/MEK/MAPK Pathway via FRS2 Phosphorylation in Endothelial Cells

Angiogeneshämmare sannolikt komplement vid cancerbehandlingar

Christofferson, R; Claesson-Welsh, L; Muhr, C

Part of Läkartidningen, p. 4138, 2002

Heparin amplifies platelet-derived growth factor (PDGF)- BB-induced PDGFalpha -receptor but not PDGF beta -receptor tyrosine phosphorylation inheparan sulfate-deficient cells. Effects on signal transduction andbiological responses.

Rolny, C; Spillmann, D; Lindahl, U; Claesson-Welsh, L

Part of J Biol Chem, p. 19315, 2002

Endostatin-induced tyrosine kinase signaling through the Shb adaptor protein regulates endothelial cell apoptosis

Dixelius, Johan; Larsson, Helena; Sasaki, Takako; Holmqvist, Kristina et al.

Part of Blood, p. 3403-3411, 2000

Platelet-Derived Growth Factor-Mediated Signaling through the Shb Adaptor Protein: Effects on Cytoskeletal Organization

Hooshmand-Rad, Roya; Lu, Lingge; Heldin, Carl-Henrik; Claesson-Welsh, Lena et al.

Part of Experimental Cell Research, p. 245-254, 2000

• DOI for Platelet-Derived Growth Factor-Mediated Signaling through the Shb Adaptor Protein: Effects on Cytoskeletal Organization

Platelet-derived growth factor beta receptor regulates interstitial fluid homeostasis through phosphatidylinositol-3' kinase signaling

Heuchel, Rainer; Berg, Ansgar; Tallquist, Michelle; Åhlén, Karina et al.

Part of Proc Natl Acad Sci U S A, p. 11410-5, 1999

Phosphoinositide 3 kinase is critical for survival, mitogenesis and migration but not for differentiation of endothelial cells.

Qi, J H; Matsumoto, T; Huang, K; Olausson, K et al.

Part of Angiogenesis, p. 371-80, 1999

Angiostatin induces endothelial cell apoptosis and activation of focal adhesion kinase independently of the integrin-binding motif RGD

Claesson-Welsh, Lena; Welsh, Michael; Ito, Nobuyuki; Anand-Apte, Bela et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 5579-5583, 1998

Placenta growth factor stimulates MAP kinase and mitogenicity but not phospholipase C-g and migration of Flt 1 expressing cells.

Landgren, Eva; Schiller, Petter; Cao, Yihai; Claesson-Welsh, Lena

Part of Oncogene, p. 359, 1998

Phosphorylation of a 72-kDa protein in PDGF-stimulated cells which forms complex with c-Crk, c-Fyn and Eps15.

Hansen, Klaus; Rönnstrand, Lars; Claesson-Welsh, Lena; Heldin, Carl-Henrik

Part of FEBS Letters, p. 195, 1997

Molecular interactions of the Src homology 2 domain protein Shb with phosphotyrosine residues, tyrosine kinase receptors and Src homology 3 domain proteins

Karlsson, Torbjörn; Songyang, Z; Landgren, E; Lavergne, C et al.

Part of Oncogene, p. 1475-1483, 1995

A unique autophosphorylation site in the platelet-derived growth factor alpha receptor from a heterodimeric receptor complex

Rupp, Eva; Siegbahn, Agneta; Rönnstrand, Lars; Wernstedt, Christer et al.

Part of European Journal of Biochemistry, p. 29-41, 1994

Platelet-derived growth factor: isoform-specific signalling via heterodimeric or homodimeric receptor complexes

Heldin, Carl-Henrik; Östman, Arne; Eriksson, Anders; Siegbahn, Agneta et al.

Part of Kidney International, p. 571-574, 1992

• DOI for Platelet-derived growth factor: isoform-specific signalling via heterodimeric or homodimeric receptor complexes

Activation of the human c-kit product by ligand-induced dimerization mediates circular actin reorganization and chemotaxis

Blume-Jensen, Peter; Claesson-Welsh, Lena; Siegbahn, Agneta; Zsebo, Krisztina M. et al.

Part of EMBO Journal, p. 4121-4128, 1991

Permeability of the Endothelial Barrier: Identifying and Reconciling Controversies

Claesson-Welsh, Lena; Dejana, Elisabetta; McDonald, Donald M.

Part of Trends in Molecular Medicine, p. 314-331, 2021

• DOI for Permeability of the Endothelial Barrier: Identifying and Reconciling Controversies
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Oxygen sensing: a stunningly elegant molecular machinery highjacked in cancer

Claesson-Welsh, Lena

Part of Upsala Journal of Medical Sciences, p. 205-210, 2020

• DOI for Oxygen sensing: a stunningly elegant molecular machinery highjacked in cancer
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Cytokines regulating lymphangiogenesis

Sainz-Jaspeado, Miguel; Claesson-Welsh, Lena

Part of Current Opinion in Immunology, p. 58-63, 2018

• DOI for Cytokines regulating lymphangiogenesis

Mechanisms and regulation of endothelial VEGF receptor signalling

Simons, Michael; Gordon, Emma; Claesson-Welsh, Lena

Part of Nature reviews. Molecular cell biology, p. 611-625, 2016

• DOI for Mechanisms and regulation of endothelial VEGF receptor signalling

VEGF receptor signal transduction - A brief update

Claesson-Welsh, Lena

Part of Vascular pharmacology, p. 14-17, 2016

• DOI for VEGF receptor signal transduction - A brief update

Vascular permeability - the essentials

Claesson-Welsh, Lena

Part of Upsala Journal of Medical Sciences, p. 135-143, 2015

• DOI for Vascular permeability - the essentials

VEGFA and tumour angiogenesis

Claesson-Welsh, Lena; Welsh, Michael

Part of Journal of Internal Medicine, p. 114-127, 2013

• DOI for VEGFA and tumour angiogenesis
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Blood vessels as targets in tumor therapy

Claesson-Welsh, Lena

Part of Upsala Journal of Medical Sciences, p. 178-186, 2012

• DOI for Blood vessels as targets in tumor therapy

Signal transduction by vascular endothelial growth factor receptors

Koch, Sina; Tugues, Sonia; Li, Xiujuan; Gualandi, Laura et al.

Part of Biochemical Journal, p. 169-183, 2011

• DOI for Signal transduction by vascular endothelial growth factor receptors

Vascular endothelial growth factors and receptors: Anti-angiogenic therapy in the treatment of cancer

Tugues, Sonia; Koch, Sina; Gualandi, Laura; Li, Xiujuan et al.

Part of Molecular Aspects of Medicine, p. 88-111, 2011

• DOI for Vascular endothelial growth factors and receptors: Anti-angiogenic therapy in the treatment of cancer

Embryonic stem cell models in vascular biology

Li, Xiujuan; Claesson-Welsh, Lena

Part of Journal of Thrombosis and Haemostasis, p. 53-56, 2009

• DOI for Embryonic stem cell models in vascular biology

Building blood vessels- Stem cell models in vascular biology

Jakobsson, Lars; Kreuger, Johan; Claesson-Welsh, Lena

Part of Journal of Cell Biology, p. 751-755, 2007

• DOI for Building blood vessels- Stem cell models in vascular biology

Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis.

Shibuya, Masabumi; Claesson-Welsh, Lena

Part of Exp Cell Res, p. 549-60, 2006

VEGF receptor signal transduction

Li, Xiujuan; Claesson-Welsh, Lena; Shibuya, Masabumi

Part of Angiogenesis, p. 261-284, Elsevier, 2008

• DOI for VEGF receptor signal transduction

Identification of Biomarkers and Signatures in Protein Data

Nordling, Torbjörn E. M.; Padhan, Narendra; Nelander, Sven; Claesson-Welsh, Lena

Part of 2015 IEEE 11Th International Conference On E-Science, p. 411-419, 2015

• DOI for Identification of Biomarkers and Signatures in Protein Data

Enhancing therapeutic effects of radio-immunotherapy using the novel stapled MDM2/X-p53 antagonist PM2

Mortensen, Anja C.; Morin, Eric; Brown, Christopher J; Claesson-Welsh, Lena et al.

Endothelial-specific phosphatase VEPTP negatively regulates VEGF receptor-2 activity

Pal, Sagnik; Oliveira, Filipa; Su, Yangyang; Olsen, Signe et al.