Ollie Östlund

A Modular Framework for Treatment Effect Estimation in Latent Subgroups

Lindhagen, Lars; Garmo, Hans; Östlund, Ollie

Part of Journal of Statistical Theory and Applications, p. 1064-1090, 2025

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Helicobacter pylori Screening After Acute Myocardial Infarction: The Cluster Randomized Crossover HELP-MI SWEDEHEART Trial

Hofmann, Robin; James, Stefan; Sundqvist, Martin O; Wärme, Jonatan et al.

Part of Journal of the American Medical Association (JAMA), p. 1160-1169, 2025

• DOI for Helicobacter pylori Screening After Acute Myocardial Infarction: The Cluster Randomized Crossover HELP-MI SWEDEHEART Trial

HELicobacter Pylori screening to prevent gastrointestinal bleeding in patients with acute Myocardial Infarction (HELP-MI SWEDEHEART): Design and rationale of a cluster randomized, crossover, registry-based clinical trial

Hofmann, Robin; James, Stefan; Sundqvist, Martin O.; Wärme, Jonatan et al.

Part of American Heart Journal, p. 66-74, 2025

• DOI for HELicobacter Pylori screening to prevent gastrointestinal bleeding in patients with acute Myocardial Infarction (HELP-MI SWEDEHEART): Design and rationale of a cluster randomized, crossover, registry-based clinical trial
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The Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure with Preserved Ejection Fraction (SPIRRIT-HFpEF): Rationale and design

Lund, Lars H; James, Stefan; DeVore, Adam D; Anstrom, Kevin J et al.

Part of European Journal of Heart Failure, p. 2453-2463, 2024

• DOI for The Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure with Preserved Ejection Fraction (SPIRRIT-HFpEF): Rationale and design
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Beta-Blockers after Myocardial Infarction and Preserved Ejection Fraction

Yndigegn, T.; Lindahl, Bertil; Mars, K.; Alfredsson, J. et al.

Part of New England Journal of Medicine, p. 1372-1381, 2024

• DOI for Beta-Blockers after Myocardial Infarction and Preserved Ejection Fraction

A Modular Framework for Treatment Effect Estimation in Latent Subgroups

Lindhagen, Lars; Garmo, Hans; Östlund, Ollie

Part of Journal of Statistical Theory and Applications, p. 1064-1090, 2025

• DOI for A Modular Framework for Treatment Effect Estimation in Latent Subgroups
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Helicobacter pylori Screening After Acute Myocardial Infarction: The Cluster Randomized Crossover HELP-MI SWEDEHEART Trial

Hofmann, Robin; James, Stefan; Sundqvist, Martin O; Wärme, Jonatan et al.

Part of Journal of the American Medical Association (JAMA), p. 1160-1169, 2025

• DOI for Helicobacter pylori Screening After Acute Myocardial Infarction: The Cluster Randomized Crossover HELP-MI SWEDEHEART Trial

HELicobacter Pylori screening to prevent gastrointestinal bleeding in patients with acute Myocardial Infarction (HELP-MI SWEDEHEART): Design and rationale of a cluster randomized, crossover, registry-based clinical trial

Hofmann, Robin; James, Stefan; Sundqvist, Martin O.; Wärme, Jonatan et al.

Part of American Heart Journal, p. 66-74, 2025

• DOI for HELicobacter Pylori screening to prevent gastrointestinal bleeding in patients with acute Myocardial Infarction (HELP-MI SWEDEHEART): Design and rationale of a cluster randomized, crossover, registry-based clinical trial
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The Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure with Preserved Ejection Fraction (SPIRRIT-HFpEF): Rationale and design

Lund, Lars H; James, Stefan; DeVore, Adam D; Anstrom, Kevin J et al.

Part of European Journal of Heart Failure, p. 2453-2463, 2024

• DOI for The Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure with Preserved Ejection Fraction (SPIRRIT-HFpEF): Rationale and design
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Beta-Blockers after Myocardial Infarction and Preserved Ejection Fraction

Yndigegn, T.; Lindahl, Bertil; Mars, K.; Alfredsson, J. et al.

Part of New England Journal of Medicine, p. 1372-1381, 2024

• DOI for Beta-Blockers after Myocardial Infarction and Preserved Ejection Fraction

FFR-Guided Complete or Culprit-Only PCI in Patients with Myocardial Infarction

Böhm, Felix; Mogensen, Brynjölfur; Engstrøm, Thomas; Stankovic, Goran et al.

Part of New England Journal of Medicine, p. 1481-1492, 2024

• DOI for FFR-Guided Complete or Culprit-Only PCI in Patients with Myocardial Infarction

Heterogeneity in Blood Pressure Response to 4 Antihypertensive Drugs: A Randomized Clinical Trial

Sundström, Johan; Lind, Lars; Nowrouzi, Shamim; Hagström, Emil et al.

Part of Journal of the American Medical Association (JAMA), p. 1160-1160, 2023

• DOI for Heterogeneity in Blood Pressure Response to 4 Antihypertensive Drugs: A Randomized Clinical Trial

Design and rationale of randomized evaluation of decreased usage of beta-blockers after acute myocardial infarction (REDUCE-AMI)

Yndigegn, Troels; Lindahl, Bertil; Alfredsson, Joakim; Benatar, Jocelyne et al.

Part of European Heart Journal - Cardiovascular Pharmacotherapy, p. 192-197, 2022

• DOI for Design and rationale of randomized evaluation of decreased usage of beta-blockers after acute myocardial infarction (REDUCE-AMI)
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Study protocol: The DAICY trial-dual versus single-antibiotic impregnated cement in primary hemiarthroplasty for femoral neck fracture-a register-based cluster-randomized crossover-controlled trial

Mukka, Sebastian; Hailer, Nils P.; Möller, Michael; Gordon, Max et al.

Part of Acta Orthopaedica, p. 794-800, 2022

• DOI for Study protocol: The DAICY trial-dual versus single-antibiotic impregnated cement in primary hemiarthroplasty for femoral neck fracture-a register-based cluster-randomized crossover-controlled trial
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Poor long-term prognosis in patients admitted with strong suspicion of acute myocardial infarction but discharged with another diagnosis

Lindahl, Bertil; Ljung, L.; Herlitz, J.; Alfredsson, J. et al.

Part of Journal of Internal Medicine, p. 359-372, 2021

• DOI for Poor long-term prognosis in patients admitted with strong suspicion of acute myocardial infarction but discharged with another diagnosis
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The Full Revasc (Ffr-gUidance for compLete non-cuLprit REVASCularization) Registry-based randomized clinical trial

Böhm, Felix; Mogensen, Brynjölfur; Östlund, Ollie; Engstrom, Thomas et al.

Part of American Heart Journal, p. 92-100, 2021

• DOI for The Full Revasc (Ffr-gUidance for compLete non-cuLprit REVASCularization) Registry-based randomized clinical trial
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Bivalirudin Versus Heparin Monotherapy in ST-Segment-Elevation Myocardial Infarction.

James, Stefan; Koul, Sasha; Andersson, Jonas; Angerås, Oskar et al.

Part of Circulation. Cardiovascular Interventions, 2021

• DOI for Bivalirudin Versus Heparin Monotherapy in ST-Segment-Elevation Myocardial Infarction.

A registry-based randomised trial comparing an SGLT2 inhibitor and metformin as standard treatment of early stage type 2 diabetes (SMARTEST): Rationale, design and protocol

Sundström, Johan; Kristofi, Robin; Östlund, Ollie; Bennet, Louise et al.

Part of Journal of diabetes and its complications, 2021

• DOI for A registry-based randomised trial comparing an SGLT2 inhibitor and metformin as standard treatment of early stage type 2 diabetes (SMARTEST): Rationale, design and protocol
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Oxygen therapy in suspected acute myocardial infarction and concurrent normoxemic chronic obstructive pulmonary disease: a prespecified subgroup analysis from the DETO2X-AMI trial

Andell, Pontus; James, Stefan; Östlund, Ollie; Yndigegn, Troels et al.

Part of European Heart Journal, p. 984-992, 2020

• DOI for Oxygen therapy in suspected acute myocardial infarction and concurrent normoxemic chronic obstructive pulmonary disease: a prespecified subgroup analysis from the DETO2X-AMI trial

Effect of Oxygen Therapy on Cardiovascular Outcomes in Relation to Baseline Oxygen Saturation

James, Stefan; Erlinge, David; Herlitz, Johan; Alfredsson, Joakim et al.

Part of JACC, p. 502-513, 2020

• DOI for Effect of Oxygen Therapy on Cardiovascular Outcomes in Relation to Baseline Oxygen Saturation

The Precision HYpertenSIon Care (PHYSIC) study: a double-blind, randomized, repeated cross-over study

Sundström, Johan; Lind, Lars; Nowrouzi, Shamim; Lytsy, Per et al.

Part of Upsala Journal of Medical Sciences, p. 51-58, 2019

• DOI for The Precision HYpertenSIon Care (PHYSIC) study: a double-blind, randomized, repeated cross-over study
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Radial versus femoral access in patients with acute coronary syndrome undergoing invasive management: A prespecified subgroup analysis from VALIDATE-SWEDEHEART

Volz, Sebastian; Angeras, Oskar; Koul, Sasha; Haraldsson, Inger et al.

Part of European Heart Journal, p. 510-519, 2019

• DOI for Radial versus femoral access in patients with acute coronary syndrome undergoing invasive management: A prespecified subgroup analysis from VALIDATE-SWEDEHEART

Oxygen Therapy in Myocardial Infarction Patients With or Without Diabetes: A Predefined Subgroup Analysis From the DETO2X-AMI Trial

Nyström, Thomas; James, Stefan; Lindahl, Bertil; Östlund, Ollie et al.

Part of Diabetes Care, p. 2032-2041, 2019

• DOI for Oxygen Therapy in Myocardial Infarction Patients With or Without Diabetes: A Predefined Subgroup Analysis From the DETO2X-AMI Trial

Oxygen therapy in ST-elevation myocardial infarction

Hofmann, Robin; Witt, Nils; Lagerqvist, Bo; Jernberg, Tomas et al.

Part of European Heart Journal, p. 2730-2739, 2018

• DOI for Oxygen therapy in ST-elevation myocardial infarction

Long-Term Effects of Oxygen Therapy on Death or Hospitalization for Heart Failure in Patients With Suspected Acute Myocardial Infarction

Jernberg, Tomas; Lindahl, Bertil; Alfredsson, Joakim; Berglund, Ellinor et al.

Part of Circulation, p. 2754-2762, 2018

• DOI for Long-Term Effects of Oxygen Therapy on Death or Hospitalization for Heart Failure in Patients With Suspected Acute Myocardial Infarction

Design of DISCO-Direct or Subacute Coronary Angiography in Out-of-Hospital Cardiac Arrest study

Lagedal, Rickard; Elfwén, Ludvig; James, Stefan K; Oldgren, Jonas et al.

Part of American Heart Journal, p. 53-61, 2018

• DOI for Design of DISCO-Direct or Subacute Coronary Angiography in Out-of-Hospital Cardiac Arrest study

The Analgesic Effect of Oxygen in Suspected Acute Myocardial Infarction A Substudy of the DETO2X-AMI Trial

Sparv, David; Hofmann, Robin; Gunnarsson, Annika; James, Stefan K et al.

Part of JACC, p. 1590-1597, 2018

• DOI for The Analgesic Effect of Oxygen in Suspected Acute Myocardial Infarction A Substudy of the DETO2X-AMI Trial

Oxygen Therapy in Suspected Acute Myocardial Infarction

Hofmann, Robin; James, Stefan K; Jernberg, Tomas; Lindahl, Bertil et al.

Part of New England Journal of Medicine, p. 1240-1249, 2017

• DOI for Oxygen Therapy in Suspected Acute Myocardial Infarction

Biomarker-Based Risk Model to Predict Cardiovascular Mortality in Patients With Stable Coronary Disease

Lindholm, Daniel; Lindbäck, Johan; Armstrong, Paul W.; Budaj, Andrzej et al.

Part of Journal of the American College of Cardiology, p. 813-826, 2017

• DOI for Biomarker-Based Risk Model to Predict Cardiovascular Mortality in Patients With Stable Coronary Disease

Associations between tooth loss and prognostic biomarkers and the risk for cardiovascular events in patients with stable coronary heart disease

Vedin, Ola; Hagström, Emil; Östlund, Ollie; Avezum, Alvaro et al.

Part of International Journal of Cardiology, p. 271-276, 2017

• DOI for Associations between tooth loss and prognostic biomarkers and the risk for cardiovascular events in patients with stable coronary heart disease

Inflammatory Biomarkers Interleukin-6 and C-Reactive Protein and Outcomes in Stable Coronary Heart Disease: Experiences From the STABILITY (Stabilization of Atherosclerotic Plaque by Initiation of Darapladib Therapy) Trial

Held, Claes; White, Harvey D.; Stewart, Ralph A. H.; Budaj, Andrzej et al.

Part of Journal of the American Heart Association, 2017

• DOI for Inflammatory Biomarkers Interleukin-6 and C-Reactive Protein and Outcomes in Stable Coronary Heart Disease: Experiences From the STABILITY (Stabilization of Atherosclerotic Plaque by Initiation of Darapladib Therapy) Trial

Bivalirudin versus Heparin Monotherapy in Myocardial Infarction

Erlinge, D.; Omerovic, E.; Fröbert, O.; Linder, R. et al.

Part of New England Journal of Medicine, p. 1132-1142, 2017

• DOI for Bivalirudin versus Heparin Monotherapy in Myocardial Infarction

Outcome among VF/VT patients in the LINC (LUCAS IN cardiac arrest) trial-A randomised, controlled trial

Hardig, Bjarne Madsen; Lindgren, Erik; Östlund, Ollie; Herlitz, Johan et al.

Part of Resuscitation, p. 155-162, 2017

• DOI for Outcome among VF/VT patients in the LINC (LUCAS IN cardiac arrest) trial-A randomised, controlled trial

The Relationship Between Tooth Loss, Cardiovascular Biomarkers And Outcomes In Patients With Stable Coronary Heart Disease

Vedin, Ola; Hagström, Emil; Östlund, Ollie; Avezum, Alvaro et al.

Part of Journal of the American College of Cardiology, p. 1969-1969, 2016

Impact of thrombus aspiration during ST-Elevation Myocardial Infarction: a six month composite endpoint and risk of stroke analyses of the TASTE trial

Olivecrona, Goran K.; Lagerqvist, Bo; Frobert, Ole; Gudnason, Thorarinn et al.

Part of BMC Cardiovascular Disorders, 2016

• DOI for Impact of thrombus aspiration during ST-Elevation Myocardial Infarction: a six month composite endpoint and risk of stroke analyses of the TASTE trial
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Bivalirudin versus heparin in non-ST and ST-segment elevation myocardial infarction-a registry-based randomized clinical trial in the SWEDEHEART registry (the VALIDATE-SWEDEHEART trial)

Erlinge, David; Koul, Sasha; Eriksson, Peter; Schersten, Fredrik et al.

Part of American Heart Journal, p. 36-46, 2016

• DOI for Bivalirudin versus heparin in non-ST and ST-segment elevation myocardial infarction-a registry-based randomized clinical trial in the SWEDEHEART registry (the VALIDATE-SWEDEHEART trial)

Lipoprotein-Associated Phospholipase A(2) Activity Is a Marker of Risk But Not a Useful Target for Treatment in Patients With Stable Coronary Heart Disease

Wallentin, Lars; Held, Claes; Armstrong, Paul W.; Cannon, Christopher P. et al.

Part of Journal of the American Heart Association, 2016

• DOI for Lipoprotein-Associated Phospholipase A(2) Activity Is a Marker of Risk But Not a Useful Target for Treatment in Patients With Stable Coronary Heart Disease

Growth Differentiation Factor-15 (GDF-15) For Prognostication Of Outcomes In Stable Coronary Artery Disease: Experiences From The Stability Trial

Wallentin, Lars; Held, Claes; Stewart, Ralph; Budaj, Andrzej et al.

Part of Journal of the American College of Cardiology, 2015

External validation of the biomarker-based ABC-stroke risk score for atrial fibrillation

Hijazi, Ziad; Lindbäck, Johan; Östlund, Olof Petter; Siegbahn, Agneta et al.

Part of European Heart Journal, p. 710-711, 2015

Therapeutic Hypothermia for the Treatment of Acute Myocardial Infarction-Combined Analysis of the RAPID MI-ICE and the CHILL-MI Trials

Erlinge, David; Gotberg, Matthias; Noc, Marko; Lang, Irene et al.

Part of Therapeutic Hypothermia and Temperature Management, p. 77-84, 2015

• DOI for Therapeutic Hypothermia for the Treatment of Acute Myocardial Infarction-Combined Analysis of the RAPID MI-ICE and the CHILL-MI Trials

Per-Protocol and Pre-Defined population analysis of the LINC study

Rubertsson, Sten; Lindgren, Erik; Smekal, David; Östlund, Ollie et al.

Part of Resuscitation, p. 92-99, 2015

• DOI for Per-Protocol and Pre-Defined population analysis of the LINC study

Rapid Endovascular Catheter Core Cooling Combined With Cold Saline as an Adjunct to Percutaneous Coronary Intervention for the Treatment of Acute Myocardial Infarction The CHILL-MI Trial: A Randomized Controlled Study of the Use of Central Venous Catheter Core Cooling Combined With Cold Saline as an Adjunct to Percutaneous Coronary Intervention for the Treatment of Acute Myocardial Infarction

Erlinge, David; Gotberg, Matthias; Lang, Irene; Holzer, Michael et al.

Part of Journal of the American College of Cardiology, p. 1857-1865, 2014

• DOI for Rapid Endovascular Catheter Core Cooling Combined With Cold Saline as an Adjunct to Percutaneous Coronary Intervention for the Treatment of Acute Myocardial Infarction The CHILL-MI Trial: A Randomized Controlled Study of the Use of Central Venous Catheter Core Cooling Combined With Cold Saline as an Adjunct to Percutaneous Coronary Intervention for the Treatment of Acute Myocardial Infarction

Outcomes 1 Year after Thrombus Aspiration for Myocardial Infarction

Lagerqvist, Bo; Frobert, Ole; Olivecrona, Goran K.; Gudnason, Thorarinn et al.

Part of New England Journal of Medicine, p. 1111-1120, 2014

• DOI for Outcomes 1 Year after Thrombus Aspiration for Myocardial Infarction

DETermination of the role of OXygen in suspected Acute Myocardial Infarction trial

Hofmann, Robin; James, Stefan K.; Svensson, Leif; Witt, Nils et al.

Part of American Heart Journal, p. 322-328, 2014

• DOI for DETermination of the role of OXygen in suspected Acute Myocardial Infarction trial

Mechanical Chest Compressions and Simultaneous Defibrillation vs Conventional Cardiopulmonary Resuscitation in Out-of-Hospital Cardiac Arrest The LINC Randomized Trial

Rubertsson, Sten; Lindgren, Erik; Smekal, David; Östlund, Ollie et al.

Part of Journal of the American Medical Association (JAMA), p. 53-61, 2014

• DOI for Mechanical Chest Compressions and Simultaneous Defibrillation vs Conventional Cardiopulmonary Resuscitation in Out-of-Hospital Cardiac Arrest The LINC Randomized Trial

Thrombus Aspiration during ST-Segment Elevation Myocardial Infarction

Frobert, Ole; Lagerqvist, Bo; Olivecrona, Goran K.; Omerovic, Elmir et al.

Part of New England Journal of Medicine, p. 1587-1597, 2013

• DOI for Thrombus Aspiration during ST-Segment Elevation Myocardial Infarction