Maria Niklasson

p21-Dependent Senescence Induction by BMP4 Renders Glioblastoma Cells Vulnerable to Senolytics

Niklasson, Mia; Dalmo, Erika; Segerman, Anna; Rendo, Veronica et al.

Part of International Journal of Molecular Sciences, 2025

• DOI for p21-Dependent Senescence Induction by BMP4 Renders Glioblastoma Cells Vulnerable to Senolytics
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Tumor-specific migration routes of xenotransplanted human glioblastoma cells in mouse brain

Gupta, Rajesh Kumar; Niklasson, Mia; Bergström, Tobias; Segerman, Anna et al.

Part of Scientific Reports, 2024

• DOI for Tumor-specific migration routes of xenotransplanted human glioblastoma cells in mouse brain
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Modeling glioblastoma heterogeneity as a dynamic network of cell states

Larsson, Ida; Dalmo, Erika; Elgendy, Ramy; Niklasson, Mia et al.

Part of Molecular Systems Biology, 2021

• DOI for Modeling glioblastoma heterogeneity as a dynamic network of cell states
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Growth-Inhibitory Activity of Bone Morphogenetic Protein 4 in Human Glioblastoma Cell Lines Is Heterogeneous and Dependent on Reduced SOX2 Expression

Dalmo, Erika; Johansson, Patrik; Niklasson, Mia; Gustavsson, Ida et al.

Part of Molecular Cancer Research, p. 981-991, 2020

• DOI for Growth-Inhibitory Activity of Bone Morphogenetic Protein 4 in Human Glioblastoma Cell Lines Is Heterogeneous and Dependent on Reduced SOX2 Expression

COMBImage2: a parallel computational framework for higher-order drug combination analysis that includes automated plate design, matched filter based object counting and temporal data mining

Chantzi, Efthymia; Jarvius, Malin; Niklasson, Mia; Segerman, Anna et al.

Part of BMC Bioinformatics, 2019

• DOI for COMBImage2: a parallel computational framework for higher-order drug combination analysis that includes automated plate design, matched filter based object counting and temporal data mining
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p21-Dependent Senescence Induction by BMP4 Renders Glioblastoma Cells Vulnerable to Senolytics

Niklasson, Mia; Dalmo, Erika; Segerman, Anna; Rendo, Veronica et al.

Part of International Journal of Molecular Sciences, 2025

• DOI for p21-Dependent Senescence Induction by BMP4 Renders Glioblastoma Cells Vulnerable to Senolytics
• Download full text (pdf) of p21-Dependent Senescence Induction by BMP4 Renders Glioblastoma Cells Vulnerable to Senolytics

Tumor-specific migration routes of xenotransplanted human glioblastoma cells in mouse brain

Gupta, Rajesh Kumar; Niklasson, Mia; Bergström, Tobias; Segerman, Anna et al.

Part of Scientific Reports, 2024

• DOI for Tumor-specific migration routes of xenotransplanted human glioblastoma cells in mouse brain
• Download full text (pdf) of Tumor-specific migration routes of xenotransplanted human glioblastoma cells in mouse brain

Modeling glioblastoma heterogeneity as a dynamic network of cell states

Larsson, Ida; Dalmo, Erika; Elgendy, Ramy; Niklasson, Mia et al.

Part of Molecular Systems Biology, 2021

• DOI for Modeling glioblastoma heterogeneity as a dynamic network of cell states
• Download full text (pdf) of Modeling glioblastoma heterogeneity as a dynamic network of cell states

Growth-Inhibitory Activity of Bone Morphogenetic Protein 4 in Human Glioblastoma Cell Lines Is Heterogeneous and Dependent on Reduced SOX2 Expression

Dalmo, Erika; Johansson, Patrik; Niklasson, Mia; Gustavsson, Ida et al.

Part of Molecular Cancer Research, p. 981-991, 2020

• DOI for Growth-Inhibitory Activity of Bone Morphogenetic Protein 4 in Human Glioblastoma Cell Lines Is Heterogeneous and Dependent on Reduced SOX2 Expression

COMBImage2: a parallel computational framework for higher-order drug combination analysis that includes automated plate design, matched filter based object counting and temporal data mining

Chantzi, Efthymia; Jarvius, Malin; Niklasson, Mia; Segerman, Anna et al.

Part of BMC Bioinformatics, 2019

• DOI for COMBImage2: a parallel computational framework for higher-order drug combination analysis that includes automated plate design, matched filter based object counting and temporal data mining
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Mesenchymal transition and increased therapy resistance of glioblastoma cells is related to astrocyte reactivity

Niklasson, Mia; Bergström, Tobias; Jarvius, Malin; Sundström, Anders et al.

Part of Journal of Pathology, p. 295-307, 2019

• DOI for Mesenchymal transition and increased therapy resistance of glioblastoma cells is related to astrocyte reactivity

COMBImage: a modular parallel processing framework for pairwise drug combination analysis that quantifies temporal changes in label-free video microscopy movies

Chantzi, Efthymia; Jarvius, Malin; Niklasson, Mia; Segerman, Anna et al.

Part of BMC Bioinformatics, 2018

• DOI for COMBImage: a modular parallel processing framework for pairwise drug combination analysis that quantifies temporal changes in label-free video microscopy movies
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Membrane-Depolarizing Channel Blockers Induce Selective Glioma Cell Death by Impairing Nutrient Transport and Unfolded Protein/Amino Acid Responses

Niklasson, Mia; Maddalo, Gianluca; Sramkova, Zuzana; Mutlu, Ercan et al.

Part of Cancer Research, p. 1741-1752, 2017

• DOI for Membrane-Depolarizing Channel Blockers Induce Selective Glioma Cell Death by Impairing Nutrient Transport and Unfolded Protein/Amino Acid Responses

Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells

Darmanis, Spyros; Gallant, Caroline Julie; Marinescu, Voichita Dana; Niklasson, Mia et al.

Part of Cell Reports, p. 380-389, 2016

• DOI for Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells
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Clonal Variation in Drug and Radiation Response among Glioma-Initiating Cells Is Linked to Proneural-Mesenchymal Transition

Segerman, Anna; Niklasson, Mia; Haglund, Caroline; Bergström, Tobias et al.

Part of Cell Reports, p. 2994-3009, 2016

• DOI for Clonal Variation in Drug and Radiation Response among Glioma-Initiating Cells Is Linked to Proneural-Mesenchymal Transition
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The Human Glioblastoma Cell Culture Resource: Validated Cell Models Representing All Molecular Subtypes

Xie, Yuan; Bergström, Tobias; Jiang, Yiwen; Johansson, Patrik et al.

Part of EBioMedicine, p. 1351-1363, 2015

• DOI for The Human Glioblastoma Cell Culture Resource: Validated Cell Models Representing All Molecular Subtypes
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Selective Calcium Sensitivity in Immature Glioma Cancer Stem Cells

Wee, Shimei; Niklasson, Maria; Marinescu, Voichita Dana; Segerman, Anna et al.

Part of PLOS ONE, 2014

• DOI for Selective Calcium Sensitivity in Immature Glioma Cancer Stem Cells
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Vulnerability of Glioblastoma Cells to Catastrophic Vacuolization and Death Induced by a Small Molecule

Kitambi, Satish Srinivas; Toledo, Enrique M.; Usoskin, Dmitry; Wee, Shimei et al.

Part of Cell, p. 313-328, 2014

• DOI for Vulnerability of Glioblastoma Cells to Catastrophic Vacuolization and Death Induced by a Small Molecule

Platelet-derived growth factor over-expression in retinal progenitors results in abnormal retinal vessel formation

Edqvist, Per-Henrik D; Niklasson, Mia; Vidal-Sanz, Manuel; Hallböök, Finn et al.

Part of PLOS ONE, 2012

• DOI for Platelet-derived growth factor over-expression in retinal progenitors results in abnormal retinal vessel formation
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Enlarged lateral ventricles and aberrant behavior in mice overexpressing PDGF-B in embryonic neural stem cells

Niklasson, Mia; Bergström, Tobias; Zhang, X-Q; Gustafsdottir, Sigrun M et al.

Part of Experimental Cell Research, p. 2779-2789, 2010

• DOI for Enlarged lateral ventricles and aberrant behavior in mice overexpressing PDGF-B in embryonic neural stem cells

Extracellular signal-regulated protein kinase signaling is uncoupled from initial differentiation of central nervous system stem cells to neurons

Enarsson, Maria; Erlandsson, Anna; Larsson, Helena; Forsberg-Nilsson, Karin

Part of Molecular Cancer Research, p. 147-154, 2002

Immature neurons from CNS stem cells proliferate in response toplatelet-derived growth factor

Erlandsson, Anna; Enarsson, Maria; Forsberg-Nilsson, Karin

Part of Journal of Neuroscience, p. 3483-3491, 2001

Roles of PDGF for Neural Stem Cells

Enarsson, Mia

2004

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BMP4 induction of a senescence-like phenotype in human glioblastoma cells is dependent on p21

Niklasson, Mia; Dalmo, Erika; Westermark, Bengt

Targeting SOX2 in glioblastoma cells reveals heterogeneity in SOX2 dependency

Dalmo, Erika; Rosén, Gabriela; Niklasson, Mia; Bergström, Tobias et al.