Torgny Karlsson

Genetic and molecular signatures highlight diverse pathways linking obesity to type 2 diabetes

Mutie, Pascal M.; Stojanovic, Tijana; Lo Faro, Valeria; Karlsson, Torgny et al.

Part of Nature Communications, 2026

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Distinct genetic profiles of obesity have different effects on breast cancer risk: leveraging Mendelian randomisation to interrogate causal pathways and identify mediating proteins

Marchal, Marina Isabel; Mutie, Pascal M.; Azimi, Tayebeh; Deng, Yaqi A et al.

Part of Breast Cancer Research, 2026

• DOI for Distinct genetic profiles of obesity have different effects on breast cancer risk: leveraging Mendelian randomisation to interrogate causal pathways and identify mediating proteins
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Oral contraceptive use increases bone density and reduces the risk of osteoporosis

Ivansson, Emma L.; Johansson, Therese; Karlsson, Torgny; Johansson, Åsa

Part of European Journal of Epidemiology, p. 1123-1131, 2025

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Hormonal Contraceptive Formulations and Breast Cancer Risk in Adolescents and Premenopausal Women

Hadizadeh, Fatemeh; Koteci, Ardita; Karlsson, Torgny; Ek, Weronica E. et al.

Part of JAMA Oncology, p. 1497-1506, 2025

• DOI for Hormonal Contraceptive Formulations and Breast Cancer Risk in Adolescents and Premenopausal Women
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Improving accuracy in genome-wide association studies: a two-step approach for handling below limit of detection biomarker measurements

Deng, Yaqi A; Karlsson, Torgny; Johansson, Åsa

Part of NAR Genomics and Bioinformatics, 2025

• DOI for Improving accuracy in genome-wide association studies: a two-step approach for handling below limit of detection biomarker measurements
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Genetic and molecular signatures highlight diverse pathways linking obesity to type 2 diabetes

Mutie, Pascal M.; Stojanovic, Tijana; Lo Faro, Valeria; Karlsson, Torgny et al.

Part of Nature Communications, 2026

• DOI for Genetic and molecular signatures highlight diverse pathways linking obesity to type 2 diabetes
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Distinct genetic profiles of obesity have different effects on breast cancer risk: leveraging Mendelian randomisation to interrogate causal pathways and identify mediating proteins

Marchal, Marina Isabel; Mutie, Pascal M.; Azimi, Tayebeh; Deng, Yaqi A et al.

Part of Breast Cancer Research, 2026

• DOI for Distinct genetic profiles of obesity have different effects on breast cancer risk: leveraging Mendelian randomisation to interrogate causal pathways and identify mediating proteins
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Oral contraceptive use increases bone density and reduces the risk of osteoporosis

Ivansson, Emma L.; Johansson, Therese; Karlsson, Torgny; Johansson, Åsa

Part of European Journal of Epidemiology, p. 1123-1131, 2025

• DOI for Oral contraceptive use increases bone density and reduces the risk of osteoporosis
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Hormonal Contraceptive Formulations and Breast Cancer Risk in Adolescents and Premenopausal Women

Hadizadeh, Fatemeh; Koteci, Ardita; Karlsson, Torgny; Ek, Weronica E. et al.

Part of JAMA Oncology, p. 1497-1506, 2025

• DOI for Hormonal Contraceptive Formulations and Breast Cancer Risk in Adolescents and Premenopausal Women
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Improving accuracy in genome-wide association studies: a two-step approach for handling below limit of detection biomarker measurements

Deng, Yaqi A; Karlsson, Torgny; Johansson, Åsa

Part of NAR Genomics and Bioinformatics, 2025

• DOI for Improving accuracy in genome-wide association studies: a two-step approach for handling below limit of detection biomarker measurements
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Breast cancer risk during oral contraceptive use in women with high polygenic risk

Chatsatourian, Christina; Lo Faro, Valeria; Karlsson, Torgny; Hadizadeh, Fatemeh et al.

Part of Breast Cancer Research, 2025

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Time-resolved Mendelian randomization detects substantial variation in the detrimental effect of obesity throughout life

Karlsson, Torgny; Hadizadeh, Fatemeh; Rask-Andersen, Mathias; Schmitz, Daniel et al.

Part of Science Advances, 2025

• DOI for Time-resolved Mendelian randomization detects substantial variation in the detrimental effect of obesity throughout life
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Contemporary menopausal hormone therapy and risk of cardiovascular disease - a Swedish nationwide register-based emulated target trial

Johansson, Therese; Karlsson, Torgny; Bliuc, Dana; Schmitz, Daniel et al.

Part of The BMJ, 2024

• DOI for Contemporary menopausal hormone therapy and risk of cardiovascular disease - a Swedish nationwide register-based emulated target trial
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Adiposity and sex-specific cancer risk.

Rask-Andersen, Mathias; Ivansson, Emma; Höglund, Julia; Ek, Weronica E. et al.

Part of Cancer Cell, p. 1186-11970000, 2023

• DOI for Adiposity and sex-specific cancer risk.
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Population-based cohort study of oral contraceptive use and risk of depression

Johansson, Therese; Vinther Larsen, S.; Bui, M.; Ek, Weronica E. et al.

Part of Epidemiology and Psychiatric Sciences, 2023

• DOI for Population-based cohort study of oral contraceptive use and risk of depression
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Body Mass Index and the Risk of Rheumatic Disease: Linear and Nonlinear Mendelian Randomization Analyses

Karlsson, Torgny; Hadizadeh, Fatemeh; Rask-Andersen, Mathias; Johansson, Åsa et al.

Part of Arthritis & Rheumatology, p. 2027-2035, 2023

• DOI for Body Mass Index and the Risk of Rheumatic Disease: Linear and Nonlinear Mendelian Randomization Analyses
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Effects of oral contraceptives and menopausal hormone therapy on the risk of rheumatoid arthritis: a prospective cohort study

Hadizadeh, Fatemeh; Johansson, Therese; Johansson, Åsa; Karlsson, Torgny et al.

Part of Rheumatology, p. 2101-2108, 2023

• DOI for Effects of oral contraceptives and menopausal hormone therapy on the risk of rheumatoid arthritis: a prospective cohort study
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Contribution of rare whole-genome sequencing variants to plasma protein levels and the missing heritability

Kierczak, Marcin; Rafati, Nima; Höglund, Julia; Gourlé, Hadrien et al.

Part of Nature Communications, 2022

• DOI for Contribution of rare whole-genome sequencing variants to plasma protein levels and the missing heritability
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Gene-based variant analysis of whole-exome sequencing in relation to eosinophil count

Höglund, Julia; Hadizadeh, Fatemeh; Ek, Weronica E.; Karlsson, Torgny et al.

Part of Frontiers in Immunology, 2022

• DOI for Gene-based variant analysis of whole-exome sequencing in relation to eosinophil count
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Oral Contraceptives, Hormone Replacement Therapy, and Stroke Risk

Johansson, Therese; Fowler, Philip; Ek, Weronica E.; Skalkidou, Alkistis et al.

Part of Stroke, p. 3107-3115, 2022

• DOI for Oral Contraceptives, Hormone Replacement Therapy, and Stroke Risk

Investigating the Effect of Estradiol Levels on the Risk of Breast, Endometrial, and Ovarian Cancer

Johansson, Åsa; Schmitz, Daniel; Höglund, Julia; Hadizadeh, Fatemeh et al.

Part of Journal of the Endocrine Society, 2022

• DOI for Investigating the Effect of Estradiol Levels on the Risk of Breast, Endometrial, and Ovarian Cancer
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Causal effects of inflammatory protein biomarkers on inflammatory diseases

Ek, Weronica E; Karlsson, Torgny; Höglund, Julia; Rask-Andersen, Mathias et al.

Part of Science Advances, 2021

• DOI for Causal effects of inflammatory protein biomarkers on inflammatory diseases
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Characterization of the human ABO genotypes and their association to common inflammatory and cardiovascular diseases in the UK Biobank

Höglund, Julia; Karlsson, Torgny; Johansson, Therese; Ek, Weronica E. et al.

Part of American Journal of Hematology, p. 1350-1362, 2021

• DOI for Characterization of the human ABO genotypes and their association to common inflammatory and cardiovascular diseases in the UK Biobank
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Modification of Heritability for Educational Attainment and Fluid Intelligence by Socioeconomic Deprivation in the UK Biobank

Rask-Andersen, Mathias; Karlsson, Torgny; Ek, Weronica E; Johansson, Asa

Part of American Journal of Psychiatry, p. 625-634, 2021

• DOI for Modification of Heritability for Educational Attainment and Fluid Intelligence by Socioeconomic Deprivation in the UK Biobank

Genome-Wide Association Study of Estradiol Levels and the Causal Effect of Estradiol on Bone Mineral Density

Schmitz, Daniel; Ek, Weronica E.; Berggren, Elin; Höglund, Julia et al.

Part of Journal of Clinical Endocrinology and Metabolism, 2021

• DOI for Genome-Wide Association Study of Estradiol Levels and the Causal Effect of Estradiol on Bone Mineral Density
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Time-dependent effects of oral contraceptive use on breast, ovarian and endometrial cancers

Karlsson, Torgny; Johansson, Therese; Höglund, Julia; Ek, Weronica E et al.

Part of Cancer Research, p. 1153-1162, 2021

• DOI for Time-dependent effects of oral contraceptive use on breast, ovarian and endometrial cancers

The Vanishing and Appearing Sources during a Century of Observations Project. I. USNO Objects Missing in Modern Sky Surveys and Follow-up Observations of a "Missing Star"

Villarroel, Beatriz; Soodla, Johan; Comeron, Sebastien; Mattsson, Lars et al.

Part of Astronomical Journal, 2020

• DOI for The Vanishing and Appearing Sources during a Century of Observations Project. I. USNO Objects Missing in Modern Sky Surveys and Follow-up Observations of a "Missing Star"

Improved power and precision with whole genome sequencing data in genome-wide association studies of inflammatory biomarkers

Höglund, Julia; Rafati, Nima; Rask-Andersen, Mathias; Enroth, Stefan et al.

Part of Scientific Reports, 2019

• DOI for Improved power and precision with whole genome sequencing data in genome-wide association studies of inflammatory biomarkers
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Contribution of genetics to visceral adiposity and its relation to cardiovascular and metabolic disease.

Karlsson, Torgny; Rask-Andersen, Mathias; Pan, Gang; Höglund, Julia et al.

Part of Nature Medicine, p. 1390-1395, 2019

• DOI for Contribution of genetics to visceral adiposity and its relation to cardiovascular and metabolic disease.

Associations of autozygosity with a broad range of human phenotypes

Clark, David W.; Karlsson, Torgny; Sennblad, Bengt; Gyllensten, Ulf B. et al.

Part of Nature Communications, 2019

• DOI for Associations of autozygosity with a broad range of human phenotypes
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Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects

Rask-Andersen, Mathias; Karlsson, Torgny; Ek, Weronica E; Johansson, Åsa

Part of Nature Communications, 2019

• DOI for Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects
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Genome-wide association analysis of 350 000 Caucasians from the UK Biobank identifies novel loci for asthma, hay fever and eczema

Johansson, Åsa; Rask-Andersen, Mathias; Karlsson, Torgny; Ek, Weronica E

Part of Human Molecular Genetics, p. 4022-4041, 2019

• DOI for Genome-wide association analysis of 350 000 Caucasians from the UK Biobank identifies novel loci for asthma, hay fever and eczema
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Genetic variants influencing phenotypic variance heterogeneity

Ek, Weronica E; Rask-Andersen, Mathias; Karlsson, Torgny; Enroth, Stefan et al.

Part of Human Molecular Genetics, p. 799-810, 2018

• DOI for Genetic variants influencing phenotypic variance heterogeneity

Breast-feeding and risk of asthma, hay fever, and eczema

Ek, Weronica E; Karlsson, Torgny; Hernándes, Carlos Azuaje; Rask-Andersen, Mathias et al.

Part of Journal of Allergy and Clinical Immunology, p. 1157-+, 2018

• DOI for Breast-feeding and risk of asthma, hay fever, and eczema

RNA-sequence data normalization through in silico prediction of reference genes: the bacterial response to DNA damage as case study

Berghoff, Bork A.; Karlsson, Torgny; Kallman, Thomas; Wagner, Gerhart E. H. et al.

Part of BioData Mining, 2017

• DOI for RNA-sequence data normalization through in silico prediction of reference genes: the bacterial response to DNA damage as case study
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Gene-environment interaction study for BMI reveals interactions between genetic factors and physical activity, alcohol consumption and socioeconomic status.

Rask-Andersen, Mathias; Karlsson, Torgny; Ek, Weronica E; Johansson, Åsa

Part of PLOS Genetics, 2017

• DOI for Gene-environment interaction study for BMI reveals interactions between genetic factors and physical activity, alcohol consumption and socioeconomic status.
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The relative contribution of DNA methylation and genetic variants on protein biomarkers for human diseases.

Ahsan, Muhammad; Ek, Weronica E; Rask-Andersen, Mathias; Karlsson, Torgny et al.

Part of PLOS Genetics, 2017

• DOI for The relative contribution of DNA methylation and genetic variants on protein biomarkers for human diseases.
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AGN luminosity and stellar age: two missing ingredients forAGN unification as seen with iPTF supernovae

Villarroel, Beatriz; Nyholm, Anders; Karlsson, Torgny; Comeron, Sebastien et al.

Part of Astrophysical Journal, 2017

• DOI for AGN luminosity and stellar age: two missing ingredients forAGN unification as seen with iPTF supernovae

Tea and coffee consumption in relation to DNA methylation in four European cohorts

Ek, Weronica E.; Tobi, Elmar W; Ahsan, Muhammad; Lampa, Erik et al.

Part of Human Molecular Genetics, p. 3221-3231, 2017

• DOI for Tea and coffee consumption in relation to DNA methylation in four European cohorts

The chemical signature of a relic star cluster in the sextans dwarf spheroidal galaxy: Implications for near-field cosmology

Karlsson, Torgny; Bland-Hawthorn, J.; Freeman, K. C.; Silk, J.

Part of Astrophysical Journal, p. 111, 2012

• DOI for The chemical signature of a relic star cluster in the sextans dwarf spheroidal galaxy: Implications for near-field cosmology

HERES VI. Galactic chemical evolution of Si and C (Zhang+, 2011)

Zhang, L.; Karlsson, Torgny; Christlieb, N.; Korn, Andreas et al.

Part of VizieR Online Data Catalog, 2011

Stochastic chemical enrichment in metal-poor systems II.: Abundance ratios and scatter

Karlsson, Torgny; Gustafsson, Bengt

Part of Astronomy and Astrophysics, p. 879-894, 2005

• DOI for Stochastic chemical enrichment in metal-poor systems II.: Abundance ratios and scatter

A Relic Star Cluster in the Sextans Dwarf Spheroidal Galaxy: Implications for Early Star and Galaxy Formation

Karlsson, Torgny; Bland-Hawthorn, Joss

Part of Conference on the Galactic Archaeology, p. 257-260, 2012