Christel Bergström

Lipid packing contributes to the confinement of caveolae to the plasma membrane

Larsson, Elin; Kabedev, Aleksei; Pace, Hudson; Lindwall, Jakob et al.

Part of eLIFE, 2026

• DOI for Lipid packing contributes to the confinement of caveolae to the plasma membrane
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Double emulsions enable in situ generation of permeation enhancers for oral delivery of macromolecules

Pohlit, Hannah; Li, Lingxiao; Bini, Estela Isabel; Colucci, Dario et al.

Part of Journal of Colloid and Interface Science, 2026

• DOI for Double emulsions enable in situ generation of permeation enhancers for oral delivery of macromolecules
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Exploration of Colonic Mucus as A Dissolution Compartment for Orally Administered Drugs

Wu, Mingjun; Karlsson, Eva M.; Bergström, Christel

Part of AAPS Journal, 2026

• DOI for Exploration of Colonic Mucus as A Dissolution Compartment for Orally Administered Drugs
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Mechanics of small intestine motility for oral macromolecular delivery: modelling segmentation versus peristalsis

Naranjani, Benyamin; Hossain, Shakhawath; Tjakra, Marco; Azhand, Pardis et al.

Part of Drug Delivery, 2026

• DOI for Mechanics of small intestine motility for oral macromolecular delivery: modelling segmentation versus peristalsis
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Molecular dynamics simulations of a hexagonal liquid crystal phase to study drug partitioning and release mechanisms

Altun, Diyar; He, Xiguo; Bergström, Christel A. S.; Hubert, Madlen et al.

Part of Colloids and Surfaces B, 2026

• DOI for Molecular dynamics simulations of a hexagonal liquid crystal phase to study drug partitioning and release mechanisms
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Lipid packing contributes to the confinement of caveolae to the plasma membrane

Larsson, Elin; Kabedev, Aleksei; Pace, Hudson; Lindwall, Jakob et al.

Part of eLIFE, 2026

• DOI for Lipid packing contributes to the confinement of caveolae to the plasma membrane
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Double emulsions enable in situ generation of permeation enhancers for oral delivery of macromolecules

Pohlit, Hannah; Li, Lingxiao; Bini, Estela Isabel; Colucci, Dario et al.

Part of Journal of Colloid and Interface Science, 2026

• DOI for Double emulsions enable in situ generation of permeation enhancers for oral delivery of macromolecules
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Exploration of Colonic Mucus as A Dissolution Compartment for Orally Administered Drugs

Wu, Mingjun; Karlsson, Eva M.; Bergström, Christel

Part of AAPS Journal, 2026

• DOI for Exploration of Colonic Mucus as A Dissolution Compartment for Orally Administered Drugs
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Mechanics of small intestine motility for oral macromolecular delivery: modelling segmentation versus peristalsis

Naranjani, Benyamin; Hossain, Shakhawath; Tjakra, Marco; Azhand, Pardis et al.

Part of Drug Delivery, 2026

• DOI for Mechanics of small intestine motility for oral macromolecular delivery: modelling segmentation versus peristalsis
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Molecular dynamics simulations of a hexagonal liquid crystal phase to study drug partitioning and release mechanisms

Altun, Diyar; He, Xiguo; Bergström, Christel A. S.; Hubert, Madlen et al.

Part of Colloids and Surfaces B, 2026

• DOI for Molecular dynamics simulations of a hexagonal liquid crystal phase to study drug partitioning and release mechanisms
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Coadministration of a crystalline drug compromises supersaturation and membrane transport of an amorphous drug

Alkalla, Noor; Alhalaweh, Amjad; Bergström, Christel; Li, Na et al.

Part of International Journal of Pharmaceutics, 2026

• DOI for Coadministration of a crystalline drug compromises supersaturation and membrane transport of an amorphous drug

Impact of chemical structure, lipidation and formulation on luminal stability and intestinal absorption of GLP^-1 analogues

Emeh, Prosper; Englund, Maria; Harun, Said; Valencia, Zulma Santisteban et al.

Part of Journal of Controlled Release, 2025

• DOI for Impact of chemical structure, lipidation and formulation on luminal stability and intestinal absorption of GLP^-1 analogues
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Machine learning framework for investigating nano- and micro-scale particle diffusion in colonic mucus

Tjakra, Marco; Lidayová, Kristína; Avenel, Christophe; Bergström, Christel et al.

Part of Journal of Nanobiotechnology, 2025

• DOI for Machine learning framework for investigating nano- and micro-scale particle diffusion in colonic mucus
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Improved estimation of intrinsic solubility of drug-like molecules through multi-task graph transformer

Zhao, Jiaxi; Hermans, Eline; Sepassi, Kia; Tistaert, Christophe et al.

Part of Journal of Cheminformatics, 2025

• DOI for Improved estimation of intrinsic solubility of drug-like molecules through multi-task graph transformer
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Liquid crystal nanoparticles for oral combination antibiotic therapies: A strategy towards protecting commensal gut bacteria during treatment

He, Xiguo; Karlsson, Philip; Xiong, Ruisheng; Moodie, Lindon W. K. et al.

Part of Journal of Colloid and Interface Science, p. 287-300, 2025

• DOI for Liquid crystal nanoparticles for oral combination antibiotic therapies: A strategy towards protecting commensal gut bacteria during treatment
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Optimizing amorphous multidrug formulations: A particle engineering approach through spray drying

El Sayed, Mira; Alhalaweh, Amjad; Asdagh, Arash; Kovac, Lucia et al.

Part of European Journal of Pharmaceutical Sciences, 2025

• DOI for Optimizing amorphous multidrug formulations: A particle engineering approach through spray drying
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Optimized Artificial Colonic Mucus Enabling Physiologically Relevant Diffusion Studies of Drugs, Particles, and Delivery Systems

Tjakra, Marco; Chakrapeesirisuk, Nopdanai; Jacobson, Magdalena; Sellin, Mikael E. et al.

Part of Molecular Pharmaceutics, p. 4032-4045, 2025

• DOI for Optimized Artificial Colonic Mucus Enabling Physiologically Relevant Diffusion Studies of Drugs, Particles, and Delivery Systems
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Impact of surfactants on solution behavior and membrane transport of amorphous solid dispersions

Alhalaweh, Amjad; El Sayed, Mira; Kovac, Lucia; Bergström, Christel A.S.

Part of Journal of Pharmaceutical Sciences, p. 458-467, 2025

• DOI for Impact of surfactants on solution behavior and membrane transport of amorphous solid dispersions
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Experiences and Translatability of In Vitro and In Vivo Models to Evaluate Caprate as a Permeation Enhancer

Emeh, Prosper; Breitholtz, Katarina; Berg, Staffan; Vedin, Charlotta et al.

Part of Molecular Pharmaceutics, p. 313-324, 2024

• DOI for Experiences and Translatability of In Vitro and In Vivo Models to Evaluate Caprate as a Permeation Enhancer

Effect of Data Quality and Data Quantity on the Estimation of Intrinsic Solubility: Analysis Based on a Single-Source Data Set

Zhao, Jiaxi; Hermans, Eline; Sepassi, Kia; Tistaert, Christophe et al.

Part of Molecular Pharmaceutics, p. 5261-5271, 2024

• DOI for Effect of Data Quality and Data Quantity on the Estimation of Intrinsic Solubility: Analysis Based on a Single-Source Data Set
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Development of a canine artificial colonic mucus model for drug diffusion studies

Barmpatsalou, Vicky; Tjakra, Marco; Li, Lingxiao; Dubbelboer, Ilse R. et al.

Part of European Journal of Pharmaceutical Sciences, 2024

• DOI for Development of a canine artificial colonic mucus model for drug diffusion studies
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Molecular dynamics simulations of lipid composition and its impact on structural and dynamic properties of skin membrane

Altun, Diyar; Larsson, Per; Bergström, Christel; Hossain, Md Shakhawath

Part of Chemistry and Physics of Lipids, 2024

• DOI for Molecular dynamics simulations of lipid composition and its impact on structural and dynamic properties of skin membrane
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Drug solubilization in dog intestinal fluids with and without administration of lipid-rich formulations

Parrow, Albin; Kabedev, Aleksei; Larsson, Per; Johansson, Pernilla et al.

Part of Journal of Controlled Release, 2024

• DOI for Drug solubilization in dog intestinal fluids with and without administration of lipid-rich formulations
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Estimation of the concentration boundary layer adjacent to a flat surface using computational fluid dynamics

Sinko, Patrick D.; Parker, Louis; Prahl Wittberg, Lisa; Bergström, Christel A. S.

Part of International Journal of Pharmaceutics, 2024

• DOI for Estimation of the concentration boundary layer adjacent to a flat surface using computational fluid dynamics
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Excipient effects on supersaturation, particle size dynamics, and thermodynamic activity of multidrug amorphous formulations

El Sayed, Mira; Alhalaweh, Amjad; Kovac, Lucia; Bergström, Christel A.S.

Part of International Journal of Pharmaceutics, 2024

• DOI for Excipient effects on supersaturation, particle size dynamics, and thermodynamic activity of multidrug amorphous formulations

Benefits of combining supersaturating and solubilizing formulations - Is two better than one?

Alvebratt, Caroline; Karlén, Filip; Åhlén, Michelle; Edueng, Khadijah et al.

Part of International Journal of Pharmaceutics, 2024

• DOI for Benefits of combining supersaturating and solubilizing formulations - Is two better than one?

Design, Synthesis, and Evaluation of New 1H-Benzo[d]imidazole Based PqsR Inhibitors as Adjuvant Therapy for Pseudomonas aeruginosa Infections

Soukarieh, Fadi; Mashabi, Alaa; Richardson, William; Oton, Eduard Vico et al.

Part of Journal of Medicinal Chemistry, p. 1008-1023, 2024

• DOI for Design, Synthesis, and Evaluation of New 1H-Benzo[d]imidazole Based PqsR Inhibitors as Adjuvant Therapy for Pseudomonas aeruginosa Infections
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Development and characterization of solid lipid-based formulations (sLBFs) of ritonavir utilizing a lipolysis and permeation assay

Schulzen, Arne; Andreadis, Ioannis I.; Bergström, Christel A. S.; Quodbach, Julian

Part of European Journal of Pharmaceutical Sciences, 2024

• DOI for Development and characterization of solid lipid-based formulations (sLBFs) of ritonavir utilizing a lipolysis and permeation assay
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Molecular dynamics study on micelle-small molecule interactions: developing a strategy for an extensive comparison

Kabedev, Aleksei; Bergström, Christel A. S.; Larsson, Per

Part of Journal of Computer-Aided Molecular Design, 2024

• DOI for Molecular dynamics study on micelle-small molecule interactions: developing a strategy for an extensive comparison
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Analysis of stabilization mechanisms in β-lactoglobulin-based amorphous solid dispersions by experimental and computational approaches

Zhuo, Xuezhi; Foderà, Vito; Larsson, Per; Schaal, Zarah et al.

Part of European Journal of Pharmaceutical Sciences, 2024

• DOI for Analysis of stabilization mechanisms in β-lactoglobulin-based amorphous solid dispersions by experimental and computational approaches
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Synergistic stabilization of emulsion gel by nanoparticles and surfactant enables 3D printing of lipid-rich solid oral dosage forms

Johannesson, Jenny; Pathare, Malhar Manik; Johansson, Mathias; Bergström, Christel et al.

Part of Journal of Colloid and Interface Science, p. 1253-1264, 2023

• DOI for Synergistic stabilization of emulsion gel by nanoparticles and surfactant enables 3D printing of lipid-rich solid oral dosage forms
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Numerical simulation of peristalsis to study co-localization and intestinal distribution of a macromolecular drug and permeation enhancer

Naranjani, Benyamin; Sinko, Patrick D.; Bergström, Christel; Gogoll, A et al.

Part of International Journal of Biological Macromolecules, 2023

• DOI for Numerical simulation of peristalsis to study co-localization and intestinal distribution of a macromolecular drug and permeation enhancer
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Molecular Dynamics Simulations of Self-Assembling Colloids in Fed-State Human Intestinal Fluids and Their Solubilization of Lipophilic Drugs

Parrow, Albin; Larsson, Per; Augustijns, Patrick; Bergström, Christel A. S.

Part of Molecular Pharmaceutics, p. 451-460, 2023

• DOI for Molecular Dynamics Simulations of Self-Assembling Colloids in Fed-State Human Intestinal Fluids and Their Solubilization of Lipophilic Drugs
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Exploring the use of modified in vitro digestion assays for the evaluation of ritonavir loaded solid lipid-based formulations

Andreadis, Ioannis I.; Schulzen, Arne; Quodbach, Julian; Bergström, Christel

Part of European Journal of Pharmaceutical Sciences, 2023

• DOI for Exploring the use of modified in vitro digestion assays for the evaluation of ritonavir loaded solid lipid-based formulations
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Intrinsic lipolysis rate for systematic design of lipid-based formulations

Jacobsen, Ann-Christin; Kabedev, Aleksei; Sinko, Patrick D.; Palm, Johan E. et al.

Part of Drug Delivery and Translational Research, p. 1288-1304, 2023

• DOI for Intrinsic lipolysis rate for systematic design of lipid-based formulations
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Evaluation in pig of an intestinal administration device for oral peptide delivery

Berg, Staffan; Uggla, Teresia; Antonsson, Malin; Nunes, Sandro Filipe et al.

Part of Journal of Controlled Release, p. 792-801, 2023

• DOI for Evaluation in pig of an intestinal administration device for oral peptide delivery

Quality attributes for printable emulsion gels and 3D-printed tablets: Towards production of personalized dosage forms

Johannesson, Jenny; Wu, Mingjun; Johansson, Mathias; Bergström, Christel

Part of International Journal of Pharmaceutics, 2023

• DOI for Quality attributes for printable emulsion gels and 3D-printed tablets: Towards production of personalized dosage forms

Development and validation of a porcine artificial colonic mucus model reflecting the properties of native colonic mucus in pigs

Barmpatsalou, Vicky; Rodler, Agnes; Jacobson, Magdalena; Karlsson, Eva Marie-Louise et al.

Part of European Journal of Pharmaceutical Sciences, 2023

• DOI for Development and validation of a porcine artificial colonic mucus model reflecting the properties of native colonic mucus in pigs
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Comparison of cellular monolayers and an artificial membrane as absorptive membranes in the in vitro lipolysis-permeation assay

Keemink, Janneke; Hedge, Oliver; Bianco, Valentina; Hubert, Madlen et al.

Part of Journal of Pharmaceutical Sciences, p. 175-184, 2022

• DOI for Comparison of cellular monolayers and an artificial membrane as absorptive membranes in the in vitro lipolysis-permeation assay
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Membrane insertion mechanism of the caveola coat protein Cavin1

Liu, Kang-Cheng; Pace, Hudson; Larsson, Elin; Hossain, Md Shakhawath et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, 2022

• DOI for Membrane insertion mechanism of the caveola coat protein Cavin1
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Hyperthermia-Induced In Situ Drug Amorphization by Superparamagnetic Nanoparticles in Oral Dosage Forms

Ansari, Shaquib Rahman; Hempel, Nele-Johanna; Asad, Shno; Svedlindh, Peter et al.

Part of ACS Applied Materials and Interfaces, p. 21978-21988, 2022

• DOI for Hyperthermia-Induced In Situ Drug Amorphization by Superparamagnetic Nanoparticles in Oral Dosage Forms
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Impact of Intestinal Concentration and Colloidal Structure on the Permeation-Enhancing Efficiency of Sodium Caprate in the Rat

Berg, Staffan; Karrberg, Lillevi; Suljovic, Denny; Seeliger, Frank et al.

Part of Molecular Pharmaceutics, p. 200-212, 2022

• DOI for Impact of Intestinal Concentration and Colloidal Structure on the Permeation-Enhancing Efficiency of Sodium Caprate in the Rat
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Gastrointestinal mucus in dog: Physiological characteristics, composition, and structural properties

Dubbelboer, Ilse R; Barmpatsalou, Vicky; Rodler, Agnes; Karlsson, Eva et al.

Part of European journal of pharmaceutics and biopharmaceutics, p. 92-102, 2022

• DOI for Gastrointestinal mucus in dog: Physiological characteristics, composition, and structural properties

Manipulations and age-appropriateness of oral medications in pediatric oncology patients in Sweden: Need for personalized dosage forms

Johannesson, Jenny; Hansson, Paula; Bergström, Christel; Paulsson, Mattias

Part of Biomedicine and Pharmacotherapy, p. 112576-112576, 2022

• DOI for Manipulations and age-appropriateness of oral medications in pediatric oncology patients in Sweden: Need for personalized dosage forms
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Intestinal Absorption of FITC-Dextrans and Macromolecular Model Drugs in the Rat Intestinal Instillation Model

Berg, Staffan; Suljovic, Denny; Kärrberg, Lillevi; Englund, Maria et al.

Part of Molecular Pharmaceutics, p. 2564-2572, 2022

• DOI for Intestinal Absorption of FITC-Dextrans and Macromolecular Model Drugs in the Rat Intestinal Instillation Model
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Bioavailability of Celecoxib Formulated with Mesoporous Magnesium Carbonate: An In Vivo Evaluation

Zardán Gómez de la Torre, Teresa; Lindmark, Tuulikki; Cheung, Ocean; Bergström, Christel et al.

Part of Molecules, 2022

• DOI for Bioavailability of Celecoxib Formulated with Mesoporous Magnesium Carbonate: An In Vivo Evaluation
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Stabilizing Mechanisms of β-Lactoglobulin in Amorphous Solid Dispersions of Indomethacin

Kabedev, Aleksei; Zhuo, Xuezhi; Leng, Donglei; Foderà, Vito et al.

Part of Molecular Pharmaceutics, p. 3922-3933, 2022

• DOI for Stabilizing Mechanisms of β-Lactoglobulin in Amorphous Solid Dispersions of Indomethacin
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Considerations in the developability of peptides for oral administration when formulated together with transient permeation enhancers

Berg, Staffan; Edlund, Helena; Goundry, William R. F.; Bergström, Christel et al.

Part of International Journal of Pharmaceutics, 2022

• DOI for Considerations in the developability of peptides for oral administration when formulated together with transient permeation enhancers

UNGAP best practice for improving solubility data quality of orally administered drugs

Vertzoni, M.; Alsenz, J.; Augustijns, P.; Bauer-Brandl, A. et al.

Part of European Journal of Pharmaceutical Sciences, 2022

• DOI for UNGAP best practice for improving solubility data quality of orally administered drugs
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Impact of Simulated Intestinal Fluids on Dissolution, Solution Chemistry, and Membrane Transport of Amorphous Multidrug Formulations

El Sayed, Mira; Alhalaweh, Amjad; Bergström, Christel

Part of Molecular Pharmaceutics, p. 4079-4089, 2021

• DOI for Impact of Simulated Intestinal Fluids on Dissolution, Solution Chemistry, and Membrane Transport of Amorphous Multidrug Formulations
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Proteomics-Informed Identification of Luminal Targets For In Situ Diagnosis of Inflammatory Bowel Disease

Asad, Shno; Wegler, Christine; Ahl, David; Bergström, Christel A. S. et al.

Part of Journal of Pharmaceutical Sciences, p. 239-250, 2021

• DOI for Proteomics-Informed Identification of Luminal Targets For In Situ Diagnosis of Inflammatory Bowel Disease
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3D-printing of solid lipid tablets from emulsion gels

Johannesson, Jenny; Khan, Jamal; Hubert, Madlen; Teleki, Alexandra et al.

Part of International Journal of Pharmaceutics, 2021

• DOI for 3D-printing of solid lipid tablets from emulsion gels
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Physiological properties, composition and structural profiling of porcine gastrointestinal mucus

Barmpatsalou, Vicky; Dubbelboer, Ilse R; Rodler, Agnes; Jacobson, Magdalena et al.

Part of European journal of pharmaceutics and biopharmaceutics, p. 156-167, 2021

• DOI for Physiological properties, composition and structural profiling of porcine gastrointestinal mucus
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Synergistic Computational Modeling Approaches as Team Players in the Game of Solubility Predictions

Kuentz, Martin; Bergström, Christel A.S.

Part of Journal of Pharmaceutical Sciences, p. 22-34, 2021

• DOI for Synergistic Computational Modeling Approaches as Team Players in the Game of Solubility Predictions

Molecular dynamics simulations reveal membrane interactions for poorly water-soluble drugs: impact of bile solubilization and drug aggregation

Kabedev, Aleksei; Hossain, Shakhawath; Hubert, Madlen; Larsson, Per et al.

Part of Journal of Pharmaceutical Sciences, p. 176-185, 2021

• DOI for Molecular dynamics simulations reveal membrane interactions for poorly water-soluble drugs: impact of bile solubilization and drug aggregation
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In Vitro and In Vivo Evaluation of 3D Printed Capsules with Pressure Triggered Release Mechanism for Oral Peptide Delivery

Berg, Staffan; Krause, Julius; Björkbom, Anders; Walter, Katrin et al.

Part of Journal of Pharmaceutical Sciences, p. 228-238, 2021

• DOI for In Vitro and In Vivo Evaluation of 3D Printed Capsules with Pressure Triggered Release Mechanism for Oral Peptide Delivery

A Tribute to Professor Per Artursson - Scientist, Explorer, Mentor, Innovator, and Giant in Pharmaceutical Research

Matsson, Pär; Baranczewski, Pawel; Giacomini, Kathleen M.; Andersson, Tommy B. et al.

Part of Journal of Pharmaceutical Sciences, p. 2-11, 2021

• DOI for A Tribute to Professor Per Artursson - Scientist, Explorer, Mentor, Innovator, and Giant in Pharmaceutical Research

TIRF Microscopy‐Based Monitoring of Drug Permeation Across a Lipid Membrane Supported on Mesoporous Silica

Joyce, Paul; Jõemetsa, Silver; Isaksson, Simon; Hossain, Shakhawath et al.

Part of Angewandte Chemie International Edition, p. 2069-2073, 2021

• DOI for TIRF Microscopy‐Based Monitoring of Drug Permeation Across a Lipid Membrane Supported on Mesoporous Silica
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Increasing the Transport of Celecoxib over a Simulated Intestine Cell Membrane Model Using Mesoporous Magnesium Carbonate

Gómez de la Torre, Johan; Bergström, Christel; Zardán Gómez de la Torre, Teresa

Part of Molecules, 2021

• DOI for Increasing the Transport of Celecoxib over a Simulated Intestine Cell Membrane Model Using Mesoporous Magnesium Carbonate
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Design and Evaluation of New Quinazolin-4(3H)-one Derived PqsR Antagonists as Quorum Sensing Quenchers in Pseudomonas aeruginosa

Soukarieh, Fadi; Mashabi, Alaa; Richardson, William; Oton, Eduard Vico et al.

Part of ACS - Infectious Diseases, p. 2666-2685, 2021

• DOI for Design and Evaluation of New Quinazolin-4(3H)-one Derived PqsR Antagonists as Quorum Sensing Quenchers in Pseudomonas aeruginosa
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Utilizing Laser Activation of Photothermal Plasmonic Nanoparticles to Induce On-Demand Drug Amorphization inside a Tablet

Hempel, Nele-Johanna; Merkl, Padryk; Asad, Shno; Knopp, Matthias Manne et al.

Part of Molecular Pharmaceutics, p. 2254-2262, 2021

• DOI for Utilizing Laser Activation of Photothermal Plasmonic Nanoparticles to Induce On-Demand Drug Amorphization inside a Tablet

A comparison of chitosan, mesoporous silica and poly(lactic-co-glycolic) acid nanocarriers for optimising intestinal uptake of oral protein therapeutics

Wright, Leah; Joyce, Paul; Barnes, Timothy J.; Lundmark, Richard et al.

Part of Journal of Pharmaceutical Sciences, p. 217-227, 2021

• DOI for A comparison of chitosan, mesoporous silica and poly(lactic-co-glycolic) acid nanocarriers for optimising intestinal uptake of oral protein therapeutics

Investigation of Self-Emulsifying Drug-Delivery System Interaction with a Biomimetic Membrane under Conditions Relevant to the Small Intestine

Hedge, Oliver; Höök, Fredrik; Joyce, Paul; Bergström, Christel

Part of Langmuir, p. 10200-10213, 2021

• DOI for Investigation of Self-Emulsifying Drug-Delivery System Interaction with a Biomimetic Membrane under Conditions Relevant to the Small Intestine
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Pharmaceutical Profiling and Molecular Dynamics Simulations Reveal Crystallization Effects in Amorphous Formulations

Edueng, Khadijah; Kabedev, Aleksei; Ekdahl, Alyssa; Mahlin, Denny et al.

Part of International Journal of Pharmaceutics, 2021

• DOI for Pharmaceutical Profiling and Molecular Dynamics Simulations Reveal Crystallization Effects in Amorphous Formulations

Celebrating Women in the Pharmaceutical Sciences

Taylor, Lynne S.; Bergström, Christel; Lavasanifar, Afsaneh; Qian, Feng et al.

Part of Molecular Pharmaceutics, p. 1487-1490, 2021

• DOI for Celebrating Women in the Pharmaceutical Sciences

Strategies of solubility enhancement and perspectives in solubility measurements of pharmaceutical compounds

Bergström, Christel; Llinas, Antonio

Part of ADMET & DMPK, p. 176-179, 2020

• DOI for Strategies of solubility enhancement and perspectives in solubility measurements of pharmaceutical compounds
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Hit Identification of New Potent PqsR Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm Grown Pseudomonas aeruginosa

Soukarieh, Fadi; Liu, Ruiling; Romero, Manuel; Roberston, Shaun N. et al.

Part of Frontiers in Chemistry, 2020

• DOI for Hit Identification of New Potent PqsR Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm Grown Pseudomonas aeruginosa
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Insights into Dissolution and Solution Chemistry of Multidrug Formulations of Antihypertensive Drugs

El Sayed, Mira; Alhalaweh, Amjad; Bergström, Christel A. S.

Part of Molecular Pharmaceutics, p. 4018-4028, 2020

• DOI for Insights into Dissolution and Solution Chemistry of Multidrug Formulations of Antihypertensive Drugs

Acamprosate Is a Substrate of the Human Organic Anion Transporter (OAT) 1 without OAT3 Inhibitory Properties: Implications for Renal Acamprosate Secretion and Drug-Drug Interactions

Antonescu, Irina E.; Karlgren, Maria; Pedersen, Maria L.; Simoff, Ivailo et al.

Part of Pharmaceutics, 2020

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In Vitro Performance and Chemical Stability of Lipid-Based Formulations Encapsulated in a Mesoporous Magnesium Carbonate Carrier

Alvebratt, Caroline; Dening, Tahnee J; Åhlén, Michelle; Cheung, Ocean et al.

Part of Pharmaceutics, 2020

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Intrinsic Dissolution Rate Profiling of Poorly Water-Soluble Compounds in Biorelevant Dissolution Media

Teleki, Alexandra; Nylander, Olivia; Bergström, Christel

Part of Pharmaceutics, 2020

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Selection of In Vivo Predictive Dissolution Media Using Drug Substance and Physiological Properties

Mudie, Deanna M.; Samiei, Nasim; Marshall, Derrick J.; Amidon, Gregory E. et al.

Part of AAPS Journal, 2020

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Molecular Dynamics Simulations on Interindividual Variability of Intestinal Fluids: Impact on Drug Solubilization

Parrow, Albin; Larsson, Per; Augustijns, Patrick; Bergström, Christel A. S.

Part of Molecular Pharmaceutics, p. 3837-3844, 2020

• DOI for Molecular Dynamics Simulations on Interindividual Variability of Intestinal Fluids: Impact on Drug Solubilization
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Suitability of Artificial Membranes in Lipolysis-Permeation Assays of Oral Lipid-Based Formulations

Hedge, Oliver; Bergström, Christel A. S.

Part of Pharmaceutical research, 2020

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Influence of Bile Composition on Membrane Incorporation of Transient Permeability Enhancers

Hossain, Shakhawath; Joyce, Paul; Parrow, Albin; Jõemetsa, Silver et al.

Part of Molecular Pharmaceutics, p. 4226-4240, 2020

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Model-Informed Drug Discovery and Development in Pulmonary Delivery: Biopharmaceutical Pharmacometric Modeling for Formulation Evaluation of Pulmonary Suspensions

Sou, Tomás; Soukarieh, Fadi; Williams, Paul; Stocks, Michael J. et al.

Part of ACS Omega, p. 25733-25746, 2020

• DOI for Model-Informed Drug Discovery and Development in Pulmonary Delivery: Biopharmaceutical Pharmacometric Modeling for Formulation Evaluation of Pulmonary Suspensions
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An in vitro dissolution–digestion–permeation assay for the study of advanced drug delivery systems

Alvebratt, Caroline; Keemink, Janneke; Edueng, Khadijah; Cheung, Ocean et al.

Part of European journal of pharmaceutics and biopharmaceutics, p. 21-29, 2020

• DOI for An in vitro dissolution–digestion–permeation assay for the study of advanced drug delivery systems
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Model-Informed Drug Development in Pulmonary Delivery: Semimechanistic Pharmacokinetic-Pharmacodynamic Modeling for Evaluation of Treatments against Chronic Pseudomonas aeruginosa Lung Infections

Sou, Tomás; Kukavica-Ibrulj, Irena; Levesque, Roger C.; Friberg, Lena et al.

Part of Molecular Pharmaceutics, p. 1458-1469, 2020

• DOI for Model-Informed Drug Development in Pulmonary Delivery: Semimechanistic Pharmacokinetic-Pharmacodynamic Modeling for Evaluation of Treatments against Chronic Pseudomonas aeruginosa Lung Infections

Long-term physical (in)stability of spray-dried amorphous drugs: relationship with glass-forming ability and physicochemical properties

Edueng, Khadijah; Bergström, Christel; Gråsjö, Johan; Mahlin, Denny

Part of Pharmaceutics, 2019

• DOI for Long-term physical (in)stability of spray-dried amorphous drugs: relationship with glass-forming ability and physicochemical properties

Supersaturation Potential of Amorphous Active Pharmaceutical Ingredients after Long-Term Storage

Edueng, Khadijah; Mahlin, Denny; Gråsjö, Johan; Nylander, Olivia et al.

Part of Molecules, 2019

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Aggregation Behavior of Medium Chain Fatty Acids Studied by Coarse-Grained Molecular Dynamics Simulation

Hossain, Md Shakhawath; Berg, Staffan; Bergström, Christel; Larsson, Per

Part of AAPS PharmSciTech, 2019

• DOI for Aggregation Behavior of Medium Chain Fatty Acids Studied by Coarse-Grained Molecular Dynamics Simulation
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Effect of lipids on absorption of carvedilol in dogs: Is coadministration of lipids as efficient as a lipid-based formulation?

Alskär, Linda C.; Parrow, Albin; Keemink, Janneke; Pernilla, Johansson et al.

Part of Journal of Controlled Release, p. 90-100, 2019

• DOI for Effect of lipids on absorption of carvedilol in dogs: Is coadministration of lipids as efficient as a lipid-based formulation?
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The Permeation of Acamprosate Is Predominantly Caused by Paracellular Diffusion across Caco-2 Cell Monolayers: A Paracellular Modeling Approach

Antonescu, Irina E; Rasmussen, Karina F; Neuhoff, Sibylle; Fretté, Xavier et al.

Part of Molecular Pharmaceutics, p. 4636-4650, 2019

• DOI for The Permeation of Acamprosate Is Predominantly Caused by Paracellular Diffusion across Caco-2 Cell Monolayers: A Paracellular Modeling Approach

Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems

Boyd, Ben J.; Bergström, Christel; Vinarov, Zahari; Kuentz, Martin et al.

Part of European Journal of Pharmaceutical Sciences, 2019

• DOI for Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems
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Does the Intake of Ethanol Affect Oral Absorption of Poorly Soluble Drugs?

Keemink, Janneke; Sjögren, Erik; Holm, Rene; Bergström, Christel A. S.

Part of Journal of Pharmaceutical Sciences, p. 1765-1771, 2019

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Lipolysis-Permeation Setup for Simultaneous Study of Digestion and Absorption in Vitro

Keemink, Janneke; Martensson, Elin; Bergström, Christel

Part of Molecular Pharmaceutics, p. 921-930, 2019

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Fifty-Eight Years and Counting: High-Impact Publishing in Computational Pharmaceutical Sciences and Mechanism-Based Modeling

Amidon, Gregory E.; Anderson, Bradley D.; Balthasar, Joseph P.; Bergström, Christel A.S. et al.

Part of Journal of Pharmaceutical Sciences, p. 2-7, 2019

• DOI for Fifty-Eight Years and Counting: High-Impact Publishing in Computational Pharmaceutical Sciences and Mechanism-Based Modeling

Molecular Drivers of Crystallization Kinetics for Drugs in Supersaturated Aqueous Solutions

Alhalaweh, Amjad; Alzghoul, Ahmad; Bergström, Christel A. S.

Part of Journal of Pharmaceutical Sciences, p. 252-259, 2019

• DOI for Molecular Drivers of Crystallization Kinetics for Drugs in Supersaturated Aqueous Solutions
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Model-Based Drug Development in Pulmonary Delivery: Pharmacokinetic Analysis of Novel Drug Candidates for Treatment of Pseudomonas aeruginosa Lung Infection

Sou, Tomás; Kukavica-Ibrulj, Irena; Soukarieh, Fadi; Halliday, Nigel et al.

Part of Journal of Pharmaceutical Sciences, p. 630-640, 2019

• DOI for Model-Based Drug Development in Pulmonary Delivery: Pharmacokinetic Analysis of Novel Drug Candidates for Treatment of Pseudomonas aeruginosa Lung Infection
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Automated assays for thermodynamic (equilibrium) solubility determination.

Sou, Tomás; Bergström, Christel

Part of Drug Discovery Today, p. 11-19, 2018

• DOI for Automated assays for thermodynamic (equilibrium) solubility determination.

In Vivo Predictive Dissolution and Simulation Workshop Report: Facilitating the Development of Oral Drug Formulation and the Prediction of Oral Bioperformance

Tsume, Yasuhiro; Patel, Sanjaykumar; Fotaki, Nikoletta; Bergström, Christel et al.

Part of AAPS Journal, 2018

• DOI for In Vivo Predictive Dissolution and Simulation Workshop Report: Facilitating the Development of Oral Drug Formulation and the Prediction of Oral Bioperformance

A Modified In Situ Method to Determine Release from a Complex Drug Carrier in Particle-Rich Suspensions

Alvebratt, Caroline; Cheung, Ocean; Strömme, Maria; Bergström, Christel A. S.

Part of AAPS PharmSciTech, p. 2859-2865, 2018

• DOI for A Modified In Situ Method to Determine Release from a Complex Drug Carrier in Particle-Rich Suspensions
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Impact of Drug Physicochemical Properties on Lipolysis-Triggered Drug Supersaturation and Precipitation from Lipid-Based Formulations

Alskär, Linda C.; Keemink, Janneke; Johannesson, Jenny; Porter, Christopher J H et al.

Part of Molecular Pharmaceutics, p. 4733-4744, 2018

• DOI for Impact of Drug Physicochemical Properties on Lipolysis-Triggered Drug Supersaturation and Precipitation from Lipid-Based Formulations
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Caco-2 Cell Conditions Enabling Studies of Drug Absorption from Digestible Lipid-Based Formulations

Keemink, Janneke; Bergström, Christel

Part of Pharmaceutical research, 2018

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Amorphous Magnesium Carbonate Nanoparticles with Strong Stabilizing Capability for Amorphous Ibuprofen

Yang, Jiaojiao; Alvebratt, Caroline; Lu, Xi; Bergström, Christel et al.

Part of International Journal of Pharmaceutics, p. 515-521, 2018

• DOI for Amorphous Magnesium Carbonate Nanoparticles with Strong Stabilizing Capability for Amorphous Ibuprofen

Enhanced release of poorly water-soluble drugs from synergy between mesoporous magnesium carbonate and polymers

Yang, Jiaojiao; Alvebratt, Caroline; Zhang, Peng; Zardán Gómez de la Torre, Teresa et al.

Part of International Journal of Pharmaceutics, p. 183-190, 2017

• DOI for Enhanced release of poorly water-soluble drugs from synergy between mesoporous magnesium carbonate and polymers

Characterization of Solubilizing Nanoaggregates Present in Different Versions of Simulated Intestinal Fluid

Clulow, Andrew J.; Parrow, Albin; Hawley, Adrian; Khan, Jamal et al.

Part of Journal of Physical Chemistry B, p. 10869-10881, 2017

• DOI for Characterization of Solubilizing Nanoaggregates Present in Different Versions of Simulated Intestinal Fluid
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Substrate and method dependent inhibition of three ABC-transporters (MDR1, BCRP, and MRP2)

Pedersen, Jenny M.; Khan, Elin K.; Bergström, Christel; Palm, Johan et al.

Part of European Journal of Pharmaceutical Sciences, p. 70-76, 2017

• DOI for Substrate and method dependent inhibition of three ABC-transporters (MDR1, BCRP, and MRP2)

Controlled Suspensions Enable Rapid Determinations of Intrinsic Dissolution Rate and Apparent Solubility of Poorly Water-Soluble Compounds

Andersson, Sara B. E.; Alvebratt, Caroline; Bergström, Christel

Part of Pharmaceutical research, p. 1805-1816, 2017

• DOI for Controlled Suspensions Enable Rapid Determinations of Intrinsic Dissolution Rate and Apparent Solubility of Poorly Water-Soluble Compounds
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Mechanism-based selection of stabilization strategy for amorphous formulations: Insights into crystallization pathways

Edueng, Khadijah; Mahlin, Denny; Larsson, Per; Bergström, Christel

Part of Journal of Controlled Release, p. 193-202, 2017

• DOI for Mechanism-based selection of stabilization strategy for amorphous formulations: Insights into crystallization pathways
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Molecular Structuring and Phase Transition of Lipid-Based Formulations upon Water Dispersion: A Coarse-Grained Molecular Dynamics Simulation Approach

Larsson, Per; Alskär, Linda C.; Bergström, Christel

Part of Molecular Pharmaceutics, p. 4145-4153, 2017

• DOI for Molecular Structuring and Phase Transition of Lipid-Based Formulations upon Water Dispersion: A Coarse-Grained Molecular Dynamics Simulation Approach
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Investigation of the Intra- and Interlaboratory Reproducibility of a Small Scale Standardized Supersaturation and Precipitation Method

Plum, Jakob; Madsen, Cecilie M.; Teleki, Alexandra; Bevernage, Jan et al.

Part of Molecular Pharmaceutics, p. 4161-4169, 2017

• DOI for Investigation of the Intra- and Interlaboratory Reproducibility of a Small Scale Standardized Supersaturation and Precipitation Method

Interlaboratory Validation of Small-Scale Solubility and Dissolution Measurements of Poorly Water-Soluble Drugs

Andersson, Sara B. E.; Alvebratt, Caroline; Bevernage, Jan; Bonneau, Damien et al.

Part of Journal of Pharmaceutical Sciences, p. 2864-2872, 2016

• DOI for Interlaboratory Validation of Small-Scale Solubility and Dissolution Measurements of Poorly Water-Soluble Drugs

Understanding the Challenge of Beyond-Rule-of-5 Compounds Preface

Bergström, Christel A. S.; Porter, Christopher J. H.

Part of Advanced Drug Delivery Reviews, p. 1-5, 2016

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Compromised in vitro dissolution and membrane transport of multidrug amorphous formulations.

Alhalaweh, Amjad; Bergström, Christel A. S.; Taylor, Lynne S.

Part of Journal of Controlled Release, p. 172-182, 2016

• DOI for Compromised in vitro dissolution and membrane transport of multidrug amorphous formulations.

Tools for Early Prediction of Drug Loading in Lipid-Based Formulations

Alskär, Linda C.; Porter, Christopher J. H.; Bergström, Christel A. S.

Part of Molecular Pharmaceutics, p. 251-261, 2016

• DOI for Tools for Early Prediction of Drug Loading in Lipid-Based Formulations

Diffusion-Controlled Drug Release from the Mesoporous Magnesium Carbonate Upsalite®

Zhang, Peng; Gómez de La Torre, Teresa Zardán; Forsgren, Johan; Bergström, Christel et al.

Part of Journal of Pharmaceutical Sciences, p. 657-663, 2016

• DOI for Diffusion-Controlled Drug Release from the Mesoporous Magnesium Carbonate Upsalite®

Rapid determination of drug solubilization versus supersaturation in natural and digested lipids

Gautschi, Nicolas; Bergström, Christel; Kuentz, Martin

Part of International Journal of Pharmaceutics, p. 164-174, 2016

• DOI for Rapid determination of drug solubilization versus supersaturation in natural and digested lipids

Lipophilicity in Drug Development: Too Much or Not Enough?

Bergström, Christel A. S.; Yazdanian, Mehran

Part of AAPS Journal, p. 1095-1100, 2016

• DOI for Lipophilicity in Drug Development: Too Much or Not Enough?

Partitioning into Colloidal Structures of Fasted State Intestinal Fluid Studied by Molecular Dynamics Simulations

Holmboe, Michael; Larsson, Per; Anwar, Jamshed; Bergström, Christel

Part of Langmuir, p. 12732-12740, 2016

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Supersaturation of poorly soluble drugs induced by mesoporous magnesium carbonate

Zhang, Peng; Gómez de La Torre, Teresa Zardán; Welch, Ken; Bergström, Christel et al.

Part of European Journal of Pharmaceutical Sciences, p. 468-474, 2016

• DOI for Supersaturation of poorly soluble drugs induced by mesoporous magnesium carbonate

Computational Prediction of Drug Solubility in Fasted Simulated and Aspirated Human Intestinal Fluid

Fagerberg, Jonas H.; Karlsson, Eva; Ulander, Johan; Hanisch, Gunilla et al.

Part of Pharmaceutical research, p. 578-589, 2015

• DOI for Computational Prediction of Drug Solubility in Fasted Simulated and Aspirated Human Intestinal Fluid
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Computational modeling to predict the functions and impact of drug transporters

Matsson, Pär; Bergström, Christel A S

Part of In silico pharmacology, 2015

• DOI for Computational modeling to predict the functions and impact of drug transporters
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Models for Predicting Drug Absorption From Oral Lipid-Based Formulations

Persson, Linda C.; Bergström, Christel A S

Part of Current molecular biology reports, p. 141-147, 2015

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Physical stability of drugs after storage above and below the glass transition temperature: Relationship to glass-forming ability

Alhalaweh, Amjad; Alzghoul, Ahmad; Mahlin, Denny; Bergström, Christel A. S.

Part of International Journal of Pharmaceutics, p. 312-317, 2015

• DOI for Physical stability of drugs after storage above and below the glass transition temperature: Relationship to glass-forming ability
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Concomitant intake of alcohol may increase the absorption of poorly soluble drugs

Fagerberg, Jonas H.; Sjögren, Erik; Bergström, Christel A. S.

Part of European Journal of Pharmaceutical Sciences, p. 12-20, 2015

• DOI for Concomitant intake of alcohol may increase the absorption of poorly soluble drugs
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Experimental and Computational Prediction of Glass Transition Temperature of Drugs

Alzghoul, Ahmad; Alhalaweh, Amjad; Mahlin, Denny; Bergström, Christel A. S.

Part of JOURNAL OF CHEMICAL INFORMATION AND MODELING, p. 3396-3403, 2014

• DOI for Experimental and Computational Prediction of Glass Transition Temperature of Drugs

Formulation of the Microbicide INP0341 for In Vivo Protection against a Vaginal Challenge by Chlamydia trachomatis

Pedersen, Christian; Slepenkin, Anatoly; Andersson, Sara B. E.; Fagerberg, Jonas H. et al.

Part of PLOS ONE, 2014

• DOI for Formulation of the Microbicide INP0341 for In Vivo Protection against a Vaginal Challenge by Chlamydia trachomatis
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Pyridyl Benzamides as a Novel Class of Potent Inhibitors for the Kinetoplastid Trypanosoma brucei

Ferrins, Lori; Gazdik, Michelle; Rahmani, Raphael; Varghese, Swapna et al.

Part of Journal of Medicinal Chemistry, p. 6393-6402, 2014

• DOI for Pyridyl Benzamides as a Novel Class of Potent Inhibitors for the Kinetoplastid Trypanosoma brucei

Computational predictions of glass-forming ability and crystallization tendency of drug molecules

Alhalaweh, Amjad; Alzghoul, Ahmad; Kaialy, Waseem; Mahlin, Denny et al.

Part of Molecular Pharmaceutics, p. 3123-3132, 2014

• DOI for Computational predictions of glass-forming ability and crystallization tendency of drug molecules

Early pharmaceutical profiling to predict oral drug absorption: Current status and unmet needs

Bergström, Christel A. S.; Holm, Rene; Jorgensen, Soren Astrup; Andersson, Sara B. E. et al.

Part of European Journal of Pharmaceutical Sciences, p. 173-199, 2014

• DOI for Early pharmaceutical profiling to predict oral drug absorption: Current status and unmet needs

Is the full potential of the biopharmaceutics classification system reached?

Bergström, Christel A. S.; Andersson, Sara B. E.; Fagerberg, Jonas H.; Ragnarsson, Gert et al.

Part of European Journal of Pharmaceutical Sciences, p. 224-231, 2014

• DOI for Is the full potential of the biopharmaceutics classification system reached?

Early Identification of Clinically Relevant Drug Interactions with the Human Bile Salt Export Pump (BSEP; ABCB11)

Pedersen, Jenny M.; Matsson, Pär; Bergström, Christel A. S.; Hoogstraate, Janet et al.

Part of Toxicological Sciences, p. 328-343, 2013

• DOI for Early Identification of Clinically Relevant Drug Interactions with the Human Bile Salt Export Pump (BSEP; ABCB11)
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Optimizing Solubility and Permeability of a Biopharmaceutics Classification System (BCS) Class 4 Antibiotic Drug Using Lipophilic Fragments Disturbing the Crystal Lattice

Tehler, Ulrika; Fagerberg, Jonas H.; Svensson, Richard; Larhed, Mats et al.

Part of Journal of Medicinal Chemistry, p. 2690-2694, 2013

• DOI for Optimizing Solubility and Permeability of a Biopharmaceutics Classification System (BCS) Class 4 Antibiotic Drug Using Lipophilic Fragments Disturbing the Crystal Lattice

Early recognition of absorption challenges of contemporary targets: key molecular properties and in silico tools

Bergström, Christel A S

Part of Bulletin Technique Gattefossé, p. 50-57, 2013

Evaluation of the Structural Determinants of Polymeric Precipitation Inhibitors Using Solvent Shift Methods and Principle Component Analysis

Warren, Dallas B.; Bergström, Christel A. S.; Benameur, Hassan; Porter, Christopher J. H. et al.

Part of Molecular Pharmaceutics, p. 2823-2848, 2013

• DOI for Evaluation of the Structural Determinants of Polymeric Precipitation Inhibitors Using Solvent Shift Methods and Principle Component Analysis

Computational Prediction of Drug Solubility in Lipid Based Formulation Excipients

Persson, Linda C.; Porter, Christopher J. H.; Charman, William N.; Bergström, Christel A. S.

Part of Pharmaceutical research, p. 3225-3237, 2013

• DOI for Computational Prediction of Drug Solubility in Lipid Based Formulation Excipients
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Early drug development predictions of glass-forming ability and physical stability of drugs

Mahlin, Denny; Bergström, Christel A. S.

Part of European Journal of Pharmaceutical Sciences, p. 323-332, 2013

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Computational Prediction of CNS Drug Exposure Based on a Novel In Vivo Dataset

Bergstrom, Christel A. S.; Charman, Susan A.; Nicolazzo, Joseph A.

Part of Pharmaceutical research, p. 3131-3142, 2012

• DOI for Computational Prediction of CNS Drug Exposure Based on a Novel In Vivo Dataset

Ethanol Effects on Apparent Solubility of Poorly Soluble Drugs in Simulated Intestinal Fluid

Fagerberg, Jonas H.; Al-Tikriti, Yassir; Ragnarsson, Gert; Bergström, Christel A. S.

Part of Molecular Pharmaceutics, p. 1942-1952, 2012

• DOI for Ethanol Effects on Apparent Solubility of Poorly Soluble Drugs in Simulated Intestinal Fluid

In Vitro and In Silico Strategies to Identify OATP1B1 Inhibitors and Predict Clinical Drug-Drug Interactions

Karlgren, Maria; Ahlin, Gustav; Bergström, Christel A. S; Svensson, Richard et al.

Part of Pharmaceutical research, p. 411-426, 2012

• DOI for In Vitro and In Silico Strategies to Identify OATP1B1 Inhibitors and Predict Clinical Drug-Drug Interactions

Toward In Silico Prediction of Glass-Forming Ability from Molecular Structure Alone: A Screening Tool in Early Drug Development

Mahlin, Denny; Ponnambalam, Sopana; Hockerfelt, Mina Heidarian; Bergström, Christel A. S.

Part of Molecular Pharmaceutics, p. 498-506, 2011

• DOI for Toward In Silico Prediction of Glass-Forming Ability from Molecular Structure Alone: A Screening Tool in Early Drug Development

Structural Features Determining the Intestinal Epithelial Permeability and Efflux of Novel HIV-1 Protease Inhibitors

Lazorova, Lucia; Hubatsch, Ina; Ekegren, Jenny K.; Gising, Johan et al.

Part of Journal of Pharmaceutical Sciences, p. 3763-3772, 2011

• DOI for Structural Features Determining the Intestinal Epithelial Permeability and Efflux of Novel HIV-1 Protease Inhibitors

A Modified Physiological BCS for Prediction of Intestinal Absorption in Drug Discovery

Zaki, Noha M.; Artursson, Per; Bergström, Christel A. S.

Part of Molecular pharmaceutics, p. 1478-1487, 2010

• DOI for A Modified Physiological BCS for Prediction of Intestinal Absorption in Drug Discovery

Dissolution Rate and Apparent Solubility of Poorly Soluble Drugs in Biorelevant Dissolution Media

Fagerberg, Jonas H.; Tsinman, Oksana; Sun, Na; Tsinman, Konstantin et al.

Part of Molecular pharmaceutics, p. 1419-1430, 2010

• DOI for Dissolution Rate and Apparent Solubility of Poorly Soluble Drugs in Biorelevant Dissolution Media

Interaction of 140 orally administered drugs with the liver-specific organic anion transporter OATP1B1 (SLCO1B1)

Karlgren, Maria; Ahlin, Gustav; Bergström, Christel; Karlsson, Johan et al.

Part of Drug metabolism reviews (Softcover ed.), p. 304-305, 2010

Hepatitis C virus NS3 protease inhibitors: large, flexible molecules of peptide origin show satisfactory permeability across Caco-2 cells

Bergström, Christel A S; Bolin, Sara; Artursson, Per; Rönn, Robert et al.

Part of European Journal of Pharmaceutical Sciences, p. 556-563, 2009

• DOI for Hepatitis C virus NS3 protease inhibitors: large, flexible molecules of peptide origin show satisfactory permeability across Caco-2 cells

Identification of novel specific and general inhibitors of the three major human ATP-binding cassette transporters P-gp, BCRP and MRP2 among registered drugs

Matsson, Pär; Pedersen, Jenny M; Norinder, Ulf; Bergström, Christel A S et al.

Part of Pharmaceutical research, p. 1816-1831, 2009

• DOI for Identification of novel specific and general inhibitors of the three major human ATP-binding cassette transporters P-gp, BCRP and MRP2 among registered drugs

Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2)

Pedersen, Jenny; Matsson, Pär; Norinder, Ulf; Bergström, Christel A. S. et al.

Part of Journal of Medicinal Chemistry, p. 3275-3287, 2008

• DOI for Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2)

Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1

Ahlin, Gustav; Karlsson, Johan; Pedersen, Jenny M; Gustavsson, Lena et al.

Part of Journal of Medicinal Chemistry, p. 5932-5942, 2008

• DOI for Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1

Molecular characteristics for solid-state limited solubility

Wassvik, Carola M; Holmén, Anders G; Draheim, Rieke; Artursson, Per et al.

Part of Journal of Medicinal Chemistry, p. 3035-3039, 2008

• DOI for Molecular characteristics for solid-state limited solubility

Poorly soluble marketed drugs display solvation limited solubility

Bergström, Christel; Wassvik, Carola M.; Johansson, Kajsa; Hubatsch, Ina

Part of Journal of Medicinal Chemistry, p. 5858-5862, 2007

• DOI for Poorly soluble marketed drugs display solvation limited solubility

Photoinduced Formation of N₂ Molecules in Ammonium Compounds

Aziz, Emad F; Gråsjö, Johan; Forsberg, Johan; Andersson, Egil et al.

Part of Journal of Physical Chemistry A, p. 9662-9669, 2007

• DOI for Photoinduced Formation of N₂ Molecules in Ammonium Compounds

A Global Drug Inhibition Pattern for the Human ATP-Binding Cassette Transporter Breast Cancer Resistance Protein (ABCG2)

Matsson, Pär; Englund, Gunilla; Ahlin, Gustav; Bergström, Christel A. S. et al.

Part of Journal of Pharmacology and Experimental Therapeutics, p. 19-30, 2007

• DOI for A Global Drug Inhibition Pattern for the Human ATP-Binding Cassette Transporter Breast Cancer Resistance Protein (ABCG2)

Contribution of solid-state properties to the aqueous solubility of drugs.

Wassvik, Carola; Holmén, Anders; Bergström, Christel; Zamora, Ismael et al.

Part of Eur J Pharm Sci, p. 294-305, 2006

Prediction of ADMET Properties.

Norinder, U; Bergström, C

Part of ChemMedChem, p. 920-937, 2006

Computational models to predict aqueous drug solubility, permeability and intestinal absorption

Bergström, Christel

Part of Expert opinion on drug metabolism & toxicology, p. 613-627, 2005

• DOI for Computational models to predict aqueous drug solubility, permeability and intestinal absorption

X-ray yield and selectively excited X-ray emission spectra of atenolol and nadolol.

Söderström, Johan; Gråsjö, Johan; Kashtanov, S; Bergström, Christel et al.

Part of J Electr Spectr, p. 283-285, 2005

Theoretical predictions of drug absorption in drug discovery and development 

Stenberg, Patric; Bergström, Christel; Luthman, Kristina; Artursson, Per

Part of Clinical Pharmacokinetics, p. 877-899, 2002

Pickering emulsion gel enables 3D printing of lipid-rich solid oral dosage forms

Johannesson, Jenny; Pathare, Malhar Manik; Johansson, Mathias; Bergström, Christel et al.

Contemporary formulation development for inhaled pharmaceuticals

Sou, Tomás; Bergström, Christel A. S.

Part of Journal of Pharmaceutical Sciences, p. 66-86, 2021

• DOI for Contemporary formulation development for inhaled pharmaceuticals
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Molecular simulation as a computational pharmaceutics tool to predict drug solubility, solubilization processes and partitioning

Hossain, Md Shakhawath; Kabedev, Aleksei; Parrow, Albin; Bergström, Christel et al.

Part of European journal of pharmaceutics and biopharmaceutics, p. 46-55, 2019

• DOI for Molecular simulation as a computational pharmaceutics tool to predict drug solubility, solubilization processes and partitioning
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The Biopharmaceutics Classification System (BCS) and the Biopharmaceutics Drug Disposition Classification System (BDDCS): Beyond guidelines

Charalabidis, Aggelos; Sfouni, Maria; Bergström, Christel; Macheras, Panos

Part of International Journal of Pharmaceutics, p. 264-281, 2019

• DOI for The Biopharmaceutics Classification System (BCS) and the Biopharmaceutics Drug Disposition Classification System (BDDCS): Beyond guidelines

Biorelevant intrinsic dissolution profiling in early drug development: Fundamental, methodological, and industrial aspects

Bergström, Christel; Box, Karl; Holm, Rene; Matthews, Wayne et al.

Part of European journal of pharmaceutics and biopharmaceutics, p. 101-114, 2019

• DOI for Biorelevant intrinsic dissolution profiling in early drug development: Fundamental, methodological, and industrial aspects

Perspectives in solubility measurement and interpretation

Bergström, Christel A.S.; Avdeef, Alex

Part of ADMET AND DMPK, p. 88-105, 2019

• DOI for Perspectives in solubility measurement and interpretation
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Computational prediction of drug solubility in water-based systems: qualitative and quantitative approaches used in the current drug discovery and development setting

Bergström, Christel A S; Larsson, Per

Part of International Journal of Pharmaceutics, p. 185-193, 2018

• DOI for Computational prediction of drug solubility in water-based systems: qualitative and quantitative approaches used in the current drug discovery and development setting
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The Need for Restructuring the Disordered Science of Amorphous Drug Formulations

Edueng, Khadijah; Mahlin, Denny; Bergström, Christel

Part of Pharmaceutical Research, p. 1754-1772, 2017

• DOI for The Need for Restructuring the Disordered Science of Amorphous Drug Formulations
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50 years of oral lipid-based formulations: Provenance, progress and future perspectives

Feeney, Orlagh M; Crum, Matthew F; McEvoy, Claire L; Trevaskis, Natalie L et al.

Part of Advanced Drug Delivery Reviews, p. 167-194, 2016

• DOI for 50 years of oral lipid-based formulations: Provenance, progress and future perspectives

Computational prediction of formulation strategies for beyond-rule-of-5 compounds

Bergström, Christel A. S.; Charman, William N; Porter, Christopher J H

Part of Advanced Drug Delivery Reviews, p. 6-21, 2016

• DOI for Computational prediction of formulation strategies for beyond-rule-of-5 compounds
• Download full text (pdf) of Computational prediction of formulation strategies for beyond-rule-of-5 compounds

Intestinal solubility and absorption of poorly water soluble compounds: predictions, challenges and solutions

Fagerberg, Jonas H; Bergström, Christel A S

Part of Therapeutic delivery, p. 935-959, 2015

• DOI for Intestinal solubility and absorption of poorly water soluble compounds: predictions, challenges and solutions

Prediction of ADMET Properties

Norinder, Ulf; Bergström, Christel

Part of ChemMedChem, p. 920-937, 2006

• DOI for Prediction of ADMET Properties

How Physicochemical Properties of Drugs Affect Their Metabolism and Clearance

Karlgren, Maria; Bergström, Christel

Part of New Horizons in Predictive Drug Metabolism and Pharmacokinetics, p. 1-26, Royal Society of Chemistry, 2016

• DOI for How Physicochemical Properties of Drugs Affect Their Metabolism and Clearance

Computational absorption prediction

Bergström, Christel; Haeberlein, Markus; Norinder, Ulf

Part of Drug bioavailability, p. 409-432, Wiley-VCH, 2008

Prediction of ADMET Properties

Norinder, Ulf; Bergström, Christel

Part of Chemical Biology, p. 1003-1044, Wiley-VCH, 2007

Advanced methodologies to study in vitro digestion of a lipid-loaded mesoporous drug carrier

Alvebratt, Caroline; Denning, T.; Prestidge, Cliff; Bergström, Christel et al.

Part of Preclinical Form and Formulation for Drug Discovery, Gordon Research Conference 2019, 2019

Synthesis of amorphous magnesium carbonate nanoparticles for biomedical applications

Yang, Jiaojiao; Alvebratt, Caroline; Luo, Jun; Bergström, Christel et al.

Part of Bioceramics 29 ISCM 2017, 2017

A new method that enables in situ measurement of drug release from complex carrier-mediated systems

Alvebratt, Caroline; Strömme, Maria; Bergström, Christel

Part of 6th FIP Pharmaceutical Sciences World Congress2017., 2017

Dissolution studies of solid formulations - Applicability of µDiss inmonitoring supersaturation, nucleation and crystallization behavior; Casestudy: Carrier-based formulation.

Alvebratt, Caroline; Petersson, E.; Strömme, Maria; Bergström, Christel

Part of pION Fiber Optic Advanced Training Course. Uppsala, June 14-15, 2016., 2016

Diffusion controlled drug release from Mesoprous Magnesium Carbonate

Zhang, Peng; Zardán Gómez de La Torre, Teresa; Bergström, Christel; Strømme, Maria

2016

The influence of drug loading and drug-polymer interactions on physical stability and supersaturation of spray-dried solid dispersions

Edueng, Khadijah; Kabedev, Aleksei; Ekdahl, Alyssa; Mahlin, Denny et al.

Classification of promiscuous glass-formers: Limitations of differential scanning calorimetry

Edueng, Khadijah; Bergström, Christel; Mahlin, Denny

Two is better than one: benefits of combining supersaturating and solubilizing effects

Alvebratt, Caroline; Karlén, Filip; Åhlén, Michelle; Edueng, Khadijah et al.

Selective laser sintering 3D printing of personalized dosage forms: Effect of powder formulation and process parameters on the physical properties of the printed tablets

Åhlén, Michelle; Tikhomirov, Evgenii; Lamrabet, Nabil; Di Gallo, Nicole et al.

Influence of lipase products and lipolysis-permeation assay formats on drug absorption from lipid-based formulations

Hedge, Oliver; Zangana, Alaa; Bergström, Christel

Quality attributes of lipid tablets produced by semi-solid extrusion 3D printing: Towards personalized dosage forms in a clinical setting

Johannesson, Jenny; Wu, Mingjun; Johansson, Mathias; Bergström, Christel

Liquid crystal nanoparticles boost intestinal permeability of vancomycin via energy-independent uptake

He, Xiguo; Vo, Dinh Son; Lundquist, Patrik; Hubert, Madlen et al.

3D printing of liquid crystal nanoparticle containing tablets for personalized oral antibiotic delivery

He, Xiguo; Kuropka, Joram; Habtemikael, Lidia; Müller, Patricia et al.

Molecular dynamic simulations of a hexagonal liquid crystal phase to study drug partitioning and release mechanisms

Altun, Diyar; He, Xiguo; Bergström, Christel; Hubert, Madlen et al.

Development of patient-centric human artificial colonic mucus based on adult and pediatric samples under healthy and inflamed conditions

Tjakra, Marco; Teleki, Alexandra; Mickols, Evgeniya; Nyström, Niklas et al.

Improved prediction of orally administered budesonide by including the mucus as an absorption barrier

Tjakra, Marco; Alkakaei, Moamin; Karlgren, Maria; Kesisoglou, Filippos et al.

Revealing macromolecular drug absorption under the migrating motor complex: An in vivo-CFD investigation of anaesthesia effects, permeation enhancement, and species variability

Naranjani, Benyamin; Berg, Staffan; Bergström, Christel A. S.; Hossain, Shakhawath et al.

Investigating the role of intestinal mucus as a barrier for oral delivery of macromolecules and permeation enhancers

Naranjani, Benyamin; Hossain, Shakhawath; Tjakra, Marco; Sinko, Patrick D. et al.

Exploring Molecular Dynamics–Derived Descriptors for Potential Enhancement of FaSSIF Solubility Estimation

Zhao, Jiaxi; Kabedev, Aleksei; Hermans, Eline; Sepassi, Kia et al.

In vitro intestinal drug disposition device

Bergström, Christel

2020