Dan I. Andersson

When Does Evidence Create a Moral Obligation to Depart from Antibiotic Guidelines?

Ancillotti, Mirko; Andersson, Dan I.; Sandegren, Linus

Part of American Journal of Bioethics, p. 109-111, 2026

• DOI for When Does Evidence Create a Moral Obligation to Depart from Antibiotic Guidelines?
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Droplet microfluidics with image texture quantification for detection of rare antibiotic-resistant subpopulations from bloodstream infections

Agnihotri, Sagar N.; Fatsis-Kavalopoulos, Nikos; Vikdahl, Emma; Windhager, Jonas et al.

Part of npj Digital Medicine, 2026

• DOI for Droplet microfluidics with image texture quantification for detection of rare antibiotic-resistant subpopulations from bloodstream infections
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Robust antibiotic sensitization of pathogenic Pseudomonas aeruginosa via negative hysteresis in the cell envelope

Buchholz, Florian; Upterworth, Lina M.; Tueffers, Leif; Groth, Espen E. et al.

Part of Nature Communications, 2026

• DOI for Robust antibiotic sensitization of pathogenic Pseudomonas aeruginosa via negative hysteresis in the cell envelope
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Deletions of recombination genes impair tandem amplification and reshape heteroresistance mechanisms in Escherichia coli

Heidarian, Sheida; Hjort, Karin; Nicoloff, Hervé; Andersson, Dan I.

Part of mBio, 2026

• DOI for Deletions of recombination genes impair tandem amplification and reshape heteroresistance mechanisms in Escherichia coli
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The dynamic distribution of genetic tandem amplifications in a heteroresistant Escherichia coli population revealed by ultra-deep long read sequencing

Jonsson, Sofia; Guliaev, Andrei; Berryhill, Brandon A.; Andersson, Dan I. et al.

Part of Nature Communications, 2026

• DOI for The dynamic distribution of genetic tandem amplifications in a heteroresistant Escherichia coli population revealed by ultra-deep long read sequencing
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When Does Evidence Create a Moral Obligation to Depart from Antibiotic Guidelines?

Ancillotti, Mirko; Andersson, Dan I.; Sandegren, Linus

Part of American Journal of Bioethics, p. 109-111, 2026

• DOI for When Does Evidence Create a Moral Obligation to Depart from Antibiotic Guidelines?
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Droplet microfluidics with image texture quantification for detection of rare antibiotic-resistant subpopulations from bloodstream infections

Agnihotri, Sagar N.; Fatsis-Kavalopoulos, Nikos; Vikdahl, Emma; Windhager, Jonas et al.

Part of npj Digital Medicine, 2026

• DOI for Droplet microfluidics with image texture quantification for detection of rare antibiotic-resistant subpopulations from bloodstream infections
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Robust antibiotic sensitization of pathogenic Pseudomonas aeruginosa via negative hysteresis in the cell envelope

Buchholz, Florian; Upterworth, Lina M.; Tueffers, Leif; Groth, Espen E. et al.

Part of Nature Communications, 2026

• DOI for Robust antibiotic sensitization of pathogenic Pseudomonas aeruginosa via negative hysteresis in the cell envelope
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Deletions of recombination genes impair tandem amplification and reshape heteroresistance mechanisms in Escherichia coli

Heidarian, Sheida; Hjort, Karin; Nicoloff, Hervé; Andersson, Dan I.

Part of mBio, 2026

• DOI for Deletions of recombination genes impair tandem amplification and reshape heteroresistance mechanisms in Escherichia coli
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The dynamic distribution of genetic tandem amplifications in a heteroresistant Escherichia coli population revealed by ultra-deep long read sequencing

Jonsson, Sofia; Guliaev, Andrei; Berryhill, Brandon A.; Andersson, Dan I. et al.

Part of Nature Communications, 2026

• DOI for The dynamic distribution of genetic tandem amplifications in a heteroresistant Escherichia coli population revealed by ultra-deep long read sequencing
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CombiANT reader: Deep learning-based automatic image processing tool to robustly quantify antibiotic interactions

Hallström, Erik; Fatsis-Kavalopoulos, Nikos; Bimpis, Manos; Wählby, Carolina et al.

Part of PLOS Digital Health, 2025

• DOI for CombiANT reader: Deep learning-based automatic image processing tool to robustly quantify antibiotic interactions
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Interspecies interaction alters the trajectory of antibiotic resistance evolution by amplifying negative fitness epistasis

Muzafar, Suraya; Nair, Ramith R.; Andersson, Dan I.; Warsi, Omar M.

Part of The ISME Journal, 2025

• DOI for Interspecies interaction alters the trajectory of antibiotic resistance evolution by amplifying negative fitness epistasis
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Linoleic acid addition prevents Staphylococcus aureus biofilm formation on PMMA bone cement

Hong, Linglu; Hjort, Karin; Andersson, Dan; Persson, Cecilia

Part of Biofilm, 2025

• DOI for Linoleic acid addition prevents Staphylococcus aureus biofilm formation on PMMA bone cement
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Vancomycin heteroresistance (hVISA) in MRSA links to treatment failure and supports a revised PAP-AUC threshold

Fatsis-Kavalopoulos, Nikos; Kim, Yong Kyun; Chong, Yong Pil; Bae, Seongman et al.

Part of Nature Communications, 2025

• DOI for Vancomycin heteroresistance (hVISA) in MRSA links to treatment failure and supports a revised PAP-AUC threshold
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Heteroresistance and clinical outcomes: much still to be understood – Authors' reply

Fatsis-Kavalopoulos, Nikos; Heyman, Gabriel; Hjort, Karin; Jonsson, Sofia et al.

Part of The Lancet Microbe, 2025

• DOI for Heteroresistance and clinical outcomes: much still to be understood – Authors' reply
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Sublethal interaction factor (SIF), a growth-based method to analyze antibiotic combinations at sub-inhibitory concentrations

Sánchez-Hevia, Dione L.; Fatsis-Kavalopoulos, Nikolaos; Andersson, Dan I.

Part of Microbiology Spectrum, 2025

• DOI for Sublethal interaction factor (SIF), a growth-based method to analyze antibiotic combinations at sub-inhibitory concentrations
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Fast detection of synergy and antagonism in antifungal combinations used against Candida albicans clinical isolates

Lundvik, Hanna; Santini, Ramona; Altintop, Tugce Unalan; Ozenci, Volkan et al.

Part of Scientific Reports, 2025

• DOI for Fast detection of synergy and antagonism in antifungal combinations used against Candida albicans clinical isolates
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Host-Specific Adaptation of Legionella pneumophila to Single and Multiple Hosts

Moreno, Anaísa B.; Paranjape, Kiran; Cederblom, Martina; Kay, Elisabeth et al.

Part of Molecular biology and evolution, 2025

• DOI for Host-Specific Adaptation of Legionella pneumophila to Single and Multiple Hosts
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Droplet microfluidics-based detection of rare antibiotic-resistant subpopulations in Escherichia coli from bloodstream infections

Agnihotri, Sagar Narhari; Fatsis-Kavalopoulos, Nikos; Windhager, Jonas; Tenje, Maria et al.

Part of Science Advances, 2025

• DOI for Droplet microfluidics-based detection of rare antibiotic-resistant subpopulations in Escherichia coli from bloodstream infections
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Influence of printing configuration on the resulting topology and antibacterial effectiveness of PVDF-graphene composites

Spanou, Antrea; Hjort, Karin; Welch, Ken; Andersson, Dan I. et al.

Part of Polymer testing, 2025

• DOI for Influence of printing configuration on the resulting topology and antibacterial effectiveness of PVDF-graphene composites
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Selection for florfenicol resistance at sub-MIC concentrations in Pasteurella multocida

Hughes, Abigail; Pelligand, Ludovic; Andersson, Dan I.; Mead, Andrew

Part of PLOS ONE, 2025

• DOI for Selection for florfenicol resistance at sub-MIC concentrations in Pasteurella multocida
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Machine learning detection of heteroresistance in Escherichia coli

Guliaev, Andrei; Hjort, Karin; Rossi, Michele; Jonsson, Sofia et al.

Part of EBioMedicine, 2025

• DOI for Machine learning detection of heteroresistance in Escherichia coli
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Within-species variability of antibiotic interactions in Gram-negative bacteria

Tang, Po-Cheng; Sánchez-Hevia, Dione; Westhoff, Sanne; Fatsis-Kavalopoulos, Nikos et al.

Part of mBio, 2024

• DOI for Within-species variability of antibiotic interactions in Gram-negative bacteria
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High prevalence of heteroresistance in Staphylococcus aureus is caused by a multitude of mutations in core genes

Heidarian, Sheida; Guliaev, Andrei; Nicoloff, Hervé; Hjort, Karin et al.

Part of PLoS biology, 2024

• DOI for High prevalence of heteroresistance in Staphylococcus aureus is caused by a multitude of mutations in core genes
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Three concurrent mechanisms generate gene copy number variation and transient antibiotic heteroresistance

Nicoloff, Hervé; Hjort, Karin; Andersson, Dan I.; Wang, Helen

Part of Nature Communications, 2024

• DOI for Three concurrent mechanisms generate gene copy number variation and transient antibiotic heteroresistance
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Suppression of the Escherichia coli rnpA49 conditionally lethal phenotype by different compensatory mutations

Babina, Arianne M.; Kirsebom, Leif; Andersson, Dan I.

Part of RNA, p. 977-991, 2024

• DOI for Suppression of the Escherichia coli rnpA49 conditionally lethal phenotype by different compensatory mutations
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Bacteria can compensate the fitness costs of amplified resistance genes via a bypass mechanism

Pal, Ankita; Andersson, Dan I.

Part of Nature Communications, 2024

• DOI for Bacteria can compensate the fitness costs of amplified resistance genes via a bypass mechanism
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Beyond the FIC index: the extended information from fractional inhibitory concentrations (FICs)

Fatsis-Kavalopoulos, Nikos; Sánchez-Hevia, Dione; Andersson, Dan I.

Part of Journal of Antimicrobial Chemotherapy, p. 2394-2396, 2024

• DOI for Beyond the FIC index: the extended information from fractional inhibitory concentrations (FICs)
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The strength of interspecies interaction in a microbial community determines its susceptibility to invasion

Muzafar, Suraya; Nair, Ramith R.; Andersson, Dan I.; Warsi, Omar M.

Part of PLoS biology, 2024

• DOI for The strength of interspecies interaction in a microbial community determines its susceptibility to invasion
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Heteroresistance to piperacillin/tazobactam in Klebsiella pneumoniae is mediated by increased copy number of multiple β-lactamase genes

Babiker, Ahmed; Lohsen, Sarah; Van Riel, Julia; Hjort, Karin et al.

Part of JAC - Antimicrobial Resistance, 2024

• DOI for Heteroresistance to piperacillin/tazobactam in Klebsiella pneumoniae is mediated by increased copy number of multiple β-lactamase genes
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Antibiotic resistance begets more resistance: chromosomal resistance mutations mitigate fitness costs conferred by multi-resistant clinical plasmids

Nair, Ramith R.; Andersson, Dan I.; Warsi, Omar M.

Part of Microbiology Spectrum, 2024

• DOI for Antibiotic resistance begets more resistance: chromosomal resistance mutations mitigate fitness costs conferred by multi-resistant clinical plasmids
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Quantifying combined effects of colistin and ciprofloxacin against Escherichia coli in an in silico pharmacokinetic-pharmacodynamic model

Zhao, Chenyan; Kristoffersson, Anders N.; Khan, David D.; Lagerbäck, Pernilla et al.

Part of Scientific Reports, 2024

• DOI for Quantifying combined effects of colistin and ciprofloxacin against Escherichia coli in an in silico pharmacokinetic-pharmacodynamic model
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Staphylococcus aureus mutants resistant to the feed-additive monensin show increased virulence and altered purine metabolism

Warsi, Omar M.; Upterworth, Lina M.; Breidenstein, Annika; Lustig, Ulrika et al.

Part of mBio, 2024

• DOI for Staphylococcus aureus mutants resistant to the feed-additive monensin show increased virulence and altered purine metabolism
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Theoretical considerations and empirical predictions of the pharmaco- and population dynamics of heteroresistance

Levin, Bruce R.; Berryhill, Brandon A.; Gil-Gil, Teresa; Manuel, Joshua A. et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, 2024

• DOI for Theoretical considerations and empirical predictions of the pharmaco- and population dynamics of heteroresistance
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Rescue of Escherichia coli auxotrophy by de novo small proteins

Babina, Arianne M.; Surkov, Serhiy; Ye, Weihua; Jerlström-Hultqvist, Jon et al.

Part of eLIFE, 2023

• DOI for Rescue of Escherichia coli auxotrophy by de novo small proteins
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Evolutionary history of Staphylococcus aureus influences antibiotic resistance evolution

Fait, Anaelle; Andersson, Dan I.; Ingmer, Hanne

Part of Current Biology, 2023

• DOI for Evolutionary history of Staphylococcus aureus influences antibiotic resistance evolution
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Vesicle-enriched secretomes alter bacterial competitive abilities and are drivers of evolution in microbial communities

Warsi, Omar M.; Gedda, Lars; Edwards, Katarina; Andersson, Dan I.

Part of FEMS Microbiology Ecology, 2023

• DOI for Vesicle-enriched secretomes alter bacterial competitive abilities and are drivers of evolution in microbial communities
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Pervasive Selection for Clinically Relevant Resistance and Media Adaptive Mutations at Very Low Antibiotic Concentrations

Pereira, Catia; Warsi, Omar M.; Andersson, Dan I.

Part of Molecular biology and evolution, 2023

• DOI for Pervasive Selection for Clinically Relevant Resistance and Media Adaptive Mutations at Very Low Antibiotic Concentrations
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Interspecies interaction reduces selection for antibiotic resistance in Escherichia coli

Nair, Ramith R.; Andersson, Dan I.

Part of Communications Biology, 2023

• DOI for Interspecies interaction reduces selection for antibiotic resistance in Escherichia coli
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Dynamics of Extensive Drug Resistance Evolution of Mycobacterium tuberculosis in a Single Patient During 9 Years of Disease and Treatment

Hjort, Karin; Jurén, Pontus; Toro, Juan Carlos; Hoffner, Sven et al.

Part of Journal of Infectious Diseases, p. 1011-1020, 2022

• DOI for Dynamics of Extensive Drug Resistance Evolution of Mycobacterium tuberculosis in a Single Patient During 9 Years of Disease and Treatment
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Antibiotic Minimal Selective Concentrations and Fitness Costs during Biofilm and Planktonic Growth

Hjort, Karin; Fermér, Elin; Tang, Po-Cheng; Andersson, Dan I.

Part of mBio, 2022

• DOI for Antibiotic Minimal Selective Concentrations and Fitness Costs during Biofilm and Planktonic Growth

Modular 3D-Printed Peg Biofilm Device for Flexible Setup of Surface-Related Biofilm Studies

Zaborskyte, Greta; Wistrand-Yuen, Erik; Hjort, Karin; Andersson, Dan I. et al.

Part of Frontiers in Cellular and Infection Microbiology, 2022

• DOI for Modular 3D-Printed Peg Biofilm Device for Flexible Setup of Surface-Related Biofilm Studies
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Prevalence of colistin heteroresistance in carbapenem-resistant Pseudomonas aeruginosa and association with clinical outcomes in patients: an observational study

Howard-Anderson, Jessica; Davis, Michelle; Page, Alexander M.; Bower, Chris W. et al.

Part of Journal of Antimicrobial Chemotherapy, p. 793-798, 2022

• DOI for Prevalence of colistin heteroresistance in carbapenem-resistant Pseudomonas aeruginosa and association with clinical outcomes in patients: an observational study

Potential risks of treating bacterial infections with a combination of β-lactam and aminoglycoside antibiotics: A systematic quantification of antibiotic interactions in E. coli blood stream infection isolates

Fatsis-Kavalopoulos, Nikos; Roelofs, Lex; Andersson, Dan I.

Part of EBioMedicine, 2022

• DOI for Potential risks of treating bacterial infections with a combination of β-lactam and aminoglycoside antibiotics: A systematic quantification of antibiotic interactions in E. coli blood stream infection isolates
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A Microfluidic Chip for Studies of the Dynamics of Antibiotic Resistance Selection in Bacterial Biofilms

Tang, Po-Cheng; Eriksson, Olle; Sjögren, Josefin; Fatsis-Kavalopoulos, Nikos et al.

Part of Frontiers in Cellular and Infection Microbiology, 2022

• DOI for A Microfluidic Chip for Studies of the Dynamics of Antibiotic Resistance Selection in Bacterial Biofilms
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Low levels of tetracyclines select for a mutation that prevents the evolution of high-level resistance to tigecycline

Jagdmann, Jennifer; Andersson, Dan I.; Nicoloff, Hervé

Part of PLoS biology, 2022

• DOI for Low levels of tetracyclines select for a mutation that prevents the evolution of high-level resistance to tigecycline
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Structure and mechanism of a phage-encoded SAM lyase revises catalytic function of enzyme family

Guo, Xiaohu; Söderholm, Annika; Kanchugal Puttaswamy, Sandesh; Isaksen, Geir V et al.

Part of eLIFE, 2021

• DOI for Structure and mechanism of a phage-encoded SAM lyase revises catalytic function of enzyme family
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The highly dynamic nature of bacterial heteroresistance impairs its clinical detection

Pereira, Cátia; Larsson, Jimmy; Hjort, Karin; Elf, Johan et al.

Part of Communications Biology, 2021

• DOI for The highly dynamic nature of bacterial heteroresistance impairs its clinical detection
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The chemotherapeutic drug methotrexate selects for antibiotic resistance

Gudmundsdottir, Jonina S.; Fredheim, Elizabeth G. A.; Koumans, Catharina I. M.; Hegstad, Joachim et al.

Part of EBioMedicine, 2021

• DOI for The chemotherapeutic drug methotrexate selects for antibiotic resistance
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A novel type of colistin resistance genes selected from random sequence space

Knopp, Michael; Babina, Arianne M.; Gudmundsdottir, Jonina S.; Douglass, Martin et al.

Part of PLOS Genetics, 2021

• DOI for A novel type of colistin resistance genes selected from random sequence space
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Selection of Resistant Bacteria in Mallards Exposed to Subinhibitory Concentrations of Ciprofloxacin in Their Water Environment

Atterby, Clara; Nykvist, Marie; Lustig, Ulrika; Andersson, Dan I. et al.

Part of Antimicrobial Agents and Chemotherapy, 2021

• DOI for Selection of Resistant Bacteria in Mallards Exposed to Subinhibitory Concentrations of Ciprofloxacin in Their Water Environment

Mechanisms and therapeutic potential of collateral sensitivity to antibiotics

Roemhild, Roderich; Andersson, Dan I.

Part of PLoS Pathogens, 2021

• DOI for Mechanisms and therapeutic potential of collateral sensitivity to antibiotics
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An Effort Worth Making: A Qualitative Study of How Swedes Respond to Antibiotic Resistance

Ancillotti, Mirko; Eriksson, Stefan; Godskesen, Tove; Andersson, Dan I. et al.

Part of Public Health Ethics, p. 1-11, 2021

• DOI for An Effort Worth Making: A Qualitative Study of How Swedes Respond to Antibiotic Resistance
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A broad spectrum anti-bacterial peptide with an adjunct potential for tuberculosis chemotherapy

Rao, Komal Umashankar; Henderson, Domhnall Iain; Krishnan, Nitya; Puthia, Manoj et al.

Part of Scientific Reports, 2021

• DOI for A broad spectrum anti-bacterial peptide with an adjunct potential for tuberculosis chemotherapy
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Metabolic fitness landscapes predict the evolution of antibiotic resistance

Pinheiro, Fernanda; Warsi, Omar M.; Andersson, Dan I.; Laessig, Michael

Part of Nature Ecology & Evolution, p. 677-687, 2021

• DOI for Metabolic fitness landscapes predict the evolution of antibiotic resistance

Evolution of a New Function by Fusion between Phage DNA and a Bacterial Gene

Warsi, Omar; Knopp, Michael; Surkov, Serhiy; Jerlström-Hultqvist, Jon et al.

Part of Molecular biology and evolution, p. 1329-1341, 2020

• DOI for Evolution of a New Function by Fusion between Phage DNA and a Bacterial Gene
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Synonymous mutations in rpsT lead to ribosomal assembly defects that can be compensated by mutations in fis and rpoA

Knöppel, Anna; Andersson, Dan I; Näsvall, Joakim

Part of Frontiers in Microbiology, 2020

• DOI for Synonymous mutations in rpsT lead to ribosomal assembly defects that can be compensated by mutations in fis and rpoA
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Mutational Pathways and Trade-Offs Between HisA and TrpF Functions: Implications for Evolution via Gene Duplication and Divergence

Lundin, Erik; Näsvall, Joakim; Andersson, Dan I.

Part of Frontiers in Microbiology, 2020

• DOI for Mutational Pathways and Trade-Offs Between HisA and TrpF Functions: Implications for Evolution via Gene Duplication and Divergence
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CombiANT: Antibiotic interaction testing made easy

Fatsis-Kavalopoulos, Nikos; Römhild, Roderich; Tang, Po-Cheng; Kreuger, Johan et al.

Part of PLoS biology, 2020

• DOI for CombiANT: Antibiotic interaction testing made easy
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Preferences regarding antibiotic treatment and the role of antibiotic resistance: a discrete choice experiment

Ancillotti, Mirko; Eriksson, Stefan; Andersson, Dan I.; Godskesen, Tove et al.

Part of International Journal of Antimicrobial Agents, 2020

• DOI for Preferences regarding antibiotic treatment and the role of antibiotic resistance: a discrete choice experiment
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Antimicrobial Peptide Exposure Selects for Resistant and Fit Stenotrophomonas maltophilia Mutants That Show Cross-Resistance to Antibiotics

Blanco, Paula; Hjort, Karin; Martinez, Jose L.; Andersson, Dan I

Part of mSphere, 2020

• DOI for Antimicrobial Peptide Exposure Selects for Resistant and Fit Stenotrophomonas maltophilia Mutants That Show Cross-Resistance to Antibiotics
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Mutations that increase expression of the EmrAB-TolC efflux pump confer increased resistance to nitroxoline in Escherichia coli

Puértolas-Balint, Fabiola; Warsi, Omar; Linkevicius, Marius; Tang, Po-Cheng et al.

Part of Journal of Antimicrobial Chemotherapy, p. 300-308, 2020

• DOI for Mutations that increase expression of the EmrAB-TolC efflux pump confer increased resistance to nitroxoline in Escherichia coli
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Molecular mechanisms of collateral sensitivity to the antibiotic nitrofurantoin

Römhild, Roderich; Linkevicius, Marius; Andersson, Dan I

Part of PLoS biology, 2020

• DOI for Molecular mechanisms of collateral sensitivity to the antibiotic nitrofurantoin
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A portable epigenetic switch for bistable gene expression in bacteria

Olivenza, David R.; Nicoloff, Hervé; Antonia Sanchez-Romero, Maria; Cota, Ignacio et al.

Part of Scientific Reports, 2019

• DOI for A portable epigenetic switch for bistable gene expression in bacteria
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Collateral sensitivity constrains resistance evolution of the CTX-M-15 beta-lactamase

Rosenkilde, Carola E. H.; Munck, Christian; Porse, Andreas; Linkevicius, Marius et al.

Part of Nature Communications, 2019

• DOI for Collateral sensitivity constrains resistance evolution of the CTX-M-15 beta-lactamase
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Inhibition of translation termination by small molecules targeting ribosomal release factors

Ge, Xueliang; Oliveira, Ana; Hjort, Karin; Bergfors, Terese et al.

Part of Scientific Reports, 2019

• DOI for Inhibition of translation termination by small molecules targeting ribosomal release factors
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Upregulation of PBP1B and LpoB in cysB Mutants Confers Mecillinam (Amdinocillin) Resistance in Escherichia coli

Thulin, Elisabeth; Andersson, Dan I

Part of Antimicrobial Agents and Chemotherapy, 2019

• DOI for Upregulation of PBP1B and LpoB in cysB Mutants Confers Mecillinam (Amdinocillin) Resistance in Escherichia coli
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De Novo Emergence of Peptides That Confer Antibiotic Resistance

Knopp, Michael; Gudmundsdottir, Jonina S.; Nilsson, Tobias; Konig, Finja et al.

Part of mBio, 2019

• DOI for De Novo Emergence of Peptides That Confer Antibiotic Resistance
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Selection for novel metabolic capabilities in Salmonella enterica

Warsi, Omar M.; Lundin, Erik; Lustig, Ulrika; Näsvall, Joakim et al.

Part of Evolution, p. 990-1000, 2019

• DOI for Selection for novel metabolic capabilities in Salmonella enterica
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The high prevalence of antibiotic heteroresistance in pathogenic bacteria is mainly caused by gene amplification

Nicoloff, Hervé; Hjort, Karin; Levin, Bruce R.; Andersson, Dan I

Part of Nature Microbiology, p. 504-514, 2019

• DOI for The high prevalence of antibiotic heteroresistance in pathogenic bacteria is mainly caused by gene amplification

A bacteriophage enzyme induces bacterial metabolic perturbation that confers a novel promiscuous function

Jerlström-Hultqvist, Jon; Warsi, Omar; Söderholm, Annika; Knopp, Michael et al.

Part of Nature Ecology & Evolution, p. 1321-1330, 2018

• DOI for A bacteriophage enzyme induces bacterial metabolic perturbation that confers a novel promiscuous function

Occurrence of Yersinia rohdei among feral reindeer (Rangifer t. tarandus) and kelp gulls (Larus dominicanus) on the Sub-Antarctic island South Georgia.

Bonnedah, Jonas; Berg, Charlotte; Andersson, Dan I; Söderlund, Robert et al.

Part of Infection Ecology & Epidemiology, 2018

• DOI for Occurrence of Yersinia rohdei among feral reindeer (Rangifer t. tarandus) and kelp gulls (Larus dominicanus) on the Sub-Antarctic island South Georgia.
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Long-term carriage and rapid transmission of extended spectrum beta-lactamase-producing E. coli within a flock of Mallards in the absence of antibiotic selection

Sandegren, Linus; Stedt, Johan; Lustig, Ulrika; Bonnedahl, Jonas et al.

Part of Environmental Microbiology Reports, p. 576-582, 2018

• DOI for Long-term carriage and rapid transmission of extended spectrum beta-lactamase-producing E. coli within a flock of Mallards in the absence of antibiotic selection
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Different adaptive strategies in E-coli populations evolving under macronutrient limitation and metal ion limitation

Warsi, Omar M.; Andersson, Dan I; Dykhuizen, Daniel E.

Part of BMC Evolutionary Biology, 2018

• DOI for Different adaptive strategies in E-coli populations evolving under macronutrient limitation and metal ion limitation
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Genetic adaptation to growth under laboratory conditions in Escherichia coli and Salmonella enterica

Knöppel, Anna; Knopp, Michael; Albrecht, Lisa M; Lundin, Erik et al.

Part of Frontiers in Microbiology, 2018

• DOI for Genetic adaptation to growth under laboratory conditions in Escherichia coli and Salmonella enterica
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Public awareness and individual responsibility needed for judicious use of antibiotics: a qualitative study of public beliefs and perceptions

Ancillotti, Mirko; Eriksson, Stefan; Veldwijk, Jorien; Nihlén Fahlquist, Jessica et al.

Part of BMC Public Health, 2018

• DOI for Public awareness and individual responsibility needed for judicious use of antibiotics: a qualitative study of public beliefs and perceptions
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Evolution of high-level resistance during low-level antibiotic exposure

Wistrand-Yuen, Erik; Knopp, Michael; Hjort, Karin; Koskiniemi, Sanna et al.

Part of Nature Communications, 2018

• DOI for Evolution of high-level resistance during low-level antibiotic exposure
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No beneficial fitness effects of random peptides

Knopp, Michael; Andersson, Dan I

Part of Nature Ecology & Evolution, p. 1046-1047, 2018

• DOI for No beneficial fitness effects of random peptides
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Cellular hysteresis as a principle to maximize the efficacy of antibiotic therapy.

Roemhild, Roderich; Gokhale, Chaitanya S; Dirksen, Philipp; Blake, Christopher et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 9767-9772, 2018

• DOI for Cellular hysteresis as a principle to maximize the efficacy of antibiotic therapy.
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Experimental Determination and Prediction of the Fitness Effects of Random Point Mutations in the Biosynthetic Enzyme HisA

Lundin, Erik; Tang, Po-Cheng; Guy, Lionel; Näsvall, Joakim et al.

Part of Molecular biology and evolution, p. 704-718, 2018

• DOI for Experimental Determination and Prediction of the Fitness Effects of Random Point Mutations in the Biosynthetic Enzyme HisA
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Pharmacokinetics and Pharmacodynamics of Fosfomycin and Its Activity against Extended-Spectrum-beta-Lactamase-, Plasmid-Mediated AmpC-, and Carbapenemase-Producing Escherichia coli in a Murine Urinary Tract Infection Model

Zykov, Ilya Nikolaevich; Samuelsen, Orjan; Jakobsen, Lotte; Smabrekke, Lars et al.

Part of Antimicrobial Agents and Chemotherapy, 2018

• DOI for Pharmacokinetics and Pharmacodynamics of Fosfomycin and Its Activity against Extended-Spectrum-beta-Lactamase-, Plasmid-Mediated AmpC-, and Carbapenemase-Producing Escherichia coli in a Murine Urinary Tract Infection Model
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Predictable Phenotypes of Antibiotic Resistance Mutations

Knopp, Michael; Andersson, Dan I

Part of mBio, 2018

• DOI for Predictable Phenotypes of Antibiotic Resistance Mutations

Predicting mutant selection in competition experiments with ciprofloxacin-exposed Escherichia coli

Khan, David; Lagerbäck, Pernilla; Malmberg, Christer; Kristoffersson, Anders et al.

Part of International Journal of Antimicrobial Agents, p. 399-406, 2018

• DOI for Predicting mutant selection in competition experiments with ciprofloxacin-exposed Escherichia coli

Antibiotic susceptibility testing in less than 30 min using direct single-cell imaging

Baltekin, Özden; Boucharin, Alexis; Tano, Eva; Andersson, Dan I et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 9170-9175, 2017

• DOI for Antibiotic susceptibility testing in less than 30 min using direct single-cell imaging

Variation in Mutational Robustness between Different Proteins and the Predictability of Fitness Effects

Lind, Peter A.; Arvidsson, Lars; Berg, Otto; Andersson, Dan I.

Part of Molecular biology and evolution, p. 408-418, 2017

• DOI for Variation in Mutational Robustness between Different Proteins and the Predictability of Fitness Effects

Duplication-Insertion Recombineering: a fast and scar-free method for efficient transfer of multiple mutations in bacteria

Näsvall, Joakim; Knöppel, Anna; Andersson, Dan I.

Part of Nucleic Acids Research, 2017

• DOI for Duplication-Insertion Recombineering: a fast and scar-free method for efficient transfer of multiple mutations in bacteria
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Transfer and Persistence of a Multi-Drug Resistance Plasmid in situ of the Infant Gut Microbiotain the Absence of Antibiotic Treatment

Gumpert, Heidi; Kubicek-Sutherland, Jessica Z.; Porse, Andreas; Karami, Nahid et al.

Part of Frontiers in Microbiology, 2017

• DOI for Transfer and Persistence of a Multi-Drug Resistance Plasmid in situ of the Infant Gut Microbiotain the Absence of Antibiotic Treatment
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Antimicrobial peptide exposure selects for Staphylococcus aureus resistance to human defence peptides

Kubicek-Sutherland, Jessica Z.; Lofton, Hava; Vestergaard, Martin; Hjort, Karin et al.

Part of Journal of Antimicrobial Chemotherapy, p. 115-127, 2017

• DOI for Antimicrobial peptide exposure selects for Staphylococcus aureus resistance to human defence peptides
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Selection and Transmission of Antibiotic-Resistant Bacteria

Andersson, Dan I; Hughes, Diarmaid

Part of Microbiology Spectrum, 2017

• DOI for Selection and Transmission of Antibiotic-Resistant Bacteria

Can a pharmacokinetic/pharmacodynamic (PKPD) model be predictive across bacterial densities and strains?: External evaluation of a PKPD model describing longitudinal in vitro data

Nielsen, Elisabet I.; Khan, David D.; Cao, Sha; Lustig, Ulrika et al.

Part of Journal of Antimicrobial Chemotherapy, p. 3108-3116, 2017

• DOI for Can a pharmacokinetic/pharmacodynamic (PKPD) model be predictive across bacterial densities and strains?: External evaluation of a PKPD model describing longitudinal in vitro data

Reversion of High-level Mecillinam Resistance to Susceptibility in Escherichia coli During Growth in Urine.

Thulin, Elisabeth; Eriksson, Måns; Andersson, Dan I

Part of EBioMedicine, p. 111-118, 2017

• DOI for Reversion of High-level Mecillinam Resistance to Susceptibility in Escherichia coli During Growth in Urine.
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Structural and functional innovations in the real-time evolution of new (βα)₈ barrel enzymes

Newton, Matilda S.; Guo, Xiaohu; Söderholm, Annika; Näsvall, Joakim et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 4727-4732, 2017

• DOI for Structural and functional innovations in the real-time evolution of new (βα)₈ barrel enzymes

Evolution of antibiotic resistance without antibiotic exposure

Knöppel, Anna; Näsvall, Joakim; Andersson, Dan I.

Part of Antimicrobial Agents and Chemotherapy, 2017

• DOI for Evolution of antibiotic resistance without antibiotic exposure
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Resistance to the Cyclotide Cycloviolacin O2 in Salmonella enterica Caused by Different Mutations That Often Confer Cross-Resistance or Collateral Sensitivity to Other Antimicrobial Peptides

Malik, Sohaib Zafar; Linkevicius, Marius; Göransson, Ulf; Andersson, Dan I

Part of Antimicrobial Agents and Chemotherapy, 2017

• DOI for Resistance to the Cyclotide Cycloviolacin O2 in Salmonella enterica Caused by Different Mutations That Often Confer Cross-Resistance or Collateral Sensitivity to Other Antimicrobial Peptides
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Genome Dynamics of Escherichia coli during Antibiotic Treatment: Transfer, Loss, and Persistence of Genetic Elements In situ of the Infant Gut

Porse, Andreas; Gumpert, Heidi; Kubicek-Sutherland, Jessica Z.; Karami, Nahid et al.

Part of Frontiers in Cellular and Infection Microbiology, 2017

• DOI for Genome Dynamics of Escherichia coli during Antibiotic Treatment: Transfer, Loss, and Persistence of Genetic Elements In situ of the Infant Gut
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Functional Constraints on Replacing an Essential Gene with Its Ancient and Modern Homologs

Kacar, Betül; Garmendia, Eva; Tuncbag, Nurcan; Andersson, Dan I et al.

Part of mBio, 2017

• DOI for Functional Constraints on Replacing an Essential Gene with Its Ancient and Modern Homologs

Combinations of mutations in envZ, ftsI, mrdA, acrB and acrR can cause high-level carbapenem resistance in Escherichia coli

Adler, Marlen; Anjum, Mehreen; Andersson, Dan I.; Sandegren, Linus

Part of Journal of Antimicrobial Chemotherapy, p. 1188-1198, 2016

• DOI for Combinations of mutations in envZ, ftsI, mrdA, acrB and acrR can cause high-level carbapenem resistance in Escherichia coli

Unstable tandem gene amplification generates heteroresistance (variation in resistance within a population) to colistin in Salmonella enterica

Hjort, Karin; Nicoloff, Hervé; Andersson, Dan I.

Part of Molecular Microbiology, p. 274-289, 2016

• DOI for Unstable tandem gene amplification generates heteroresistance (variation in resistance within a population) to colistin in Salmonella enterica
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Bacterial Resistance To A Cyclic Antimicrobial Peptide

Malik, Sohaib Zafar; Göransson, Ulf; Andersson, Dan I

Part of Journal of Peptide Science, 2016

• DOI for Bacterial Resistance To A Cyclic Antimicrobial Peptide

Nonmutational compensation of the fitness cost of antibiotic resistance in mycobacteria by overexpression of tlyA rRNA methylase

Freihofer, Pietro; Akbergenov, Rashid; Teo, Youjin; Juskeviciene, Reda et al.

Part of RNA, p. 1836-1843, 2016

• DOI for Nonmutational compensation of the fitness cost of antibiotic resistance in mycobacteria by overexpression of tlyA rRNA methylase

Potential of tetracycline resistance proteins to evolve tigecycline resistance

Linkevicius, Marius; Sandegren, Linus; Andersson, Dan I.

Part of Antimicrobial Agents and Chemotherapy, p. 789-796, 2016

• DOI for Potential of tetracycline resistance proteins to evolve tigecycline resistance
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Fitness of Escherichia coli mutants with reduced susceptibility to tigecycline

Linkevicius, Marius; Anderssen, Jytte Mark; Sandegren, Linus; Andersson, Dan I.

Part of Journal of Antimicrobial Chemotherapy, p. 1307-1313, 2016

• DOI for Fitness of Escherichia coli mutants with reduced susceptibility to tigecycline

Indirect resistance to several classes of antibiotics in cocultures with resistant bacteria expressing antibiotic-modifying or -degrading enzymes

Nicoloff, Herve; Andersson, Dan I.

Part of Journal of Antimicrobial Chemotherapy, p. 100-110, 2016

• DOI for Indirect resistance to several classes of antibiotics in cocultures with resistant bacteria expressing antibiotic-modifying or -degrading enzymes

Compensating the fitness costs of synonymous mutations

Knöppel, Anna; Näsvall, Joakim; Andersson, Dan I.

Part of Molecular biology and evolution, p. 1461-1477, 2016

• DOI for Compensating the fitness costs of synonymous mutations
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Amelioration of the Fitness Costs of Antibiotic Resistance Due To Reduced Outer Membrane Permeability by Upregulation of Alternative Porins

Knopp, Michael; Andersson, Dan I.

Part of Molecular biology and evolution, p. 3252-3263, 2015

• DOI for Amelioration of the Fitness Costs of Antibiotic Resistance Due To Reduced Outer Membrane Permeability by Upregulation of Alternative Porins

A General Method for Rapid Determination of Antibiotic Susceptibility and Species in Bacterial Infections

Mezger, Anja; Gullberg, Erik; Goransson, Jenny; Zorzet, Anna et al.

Part of Journal of Clinical Microbiology, p. 425-432, 2015

• DOI for A General Method for Rapid Determination of Antibiotic Susceptibility and Species in Bacterial Infections
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Amdinocillin (Mecillinam) Resistance Mutations in Clinical Isolates and Laboratory-Selected Mutants of Escherichia coli

Thulin, Elisabeth; Sundqvist, Martin; Andersson, Dan I.

Part of Antimicrobial Agents and Chemotherapy, p. 1723-1732, 2015

• DOI for Amdinocillin (Mecillinam) Resistance Mutations in Clinical Isolates and Laboratory-Selected Mutants of Escherichia coli

Fitness of Salmonella mutants resistant to antimicrobial peptides

Lofton, Hava; Anwar, Naeem; Rhen, Mikael; Andersson, Dan I.

Part of Journal of Antimicrobial Chemotherapy, p. 432-440, 2015

• DOI for Fitness of Salmonella mutants resistant to antimicrobial peptides

A mechanism-based pharmacokinetic/pharmacodynamic model allows prediction of antibiotic killing from MIC values for WT and mutants

Khan, David D.; Lagerbäck, Pernilla; Cao, Sha; Lustig, Ulrika et al.

Part of Journal of Antimicrobial Chemotherapy, p. 3051-3060, 2015

• DOI for A mechanism-based pharmacokinetic/pharmacodynamic model allows prediction of antibiotic killing from MIC values for WT and mutants

Structure of AadA from Salmonella enterica: a monomeric aminoglycoside (3'')(9) adenyltransferase

Chen, Yang; Näsvall, Joakim; Wu, Shiying; Andersson, Dan I. et al.

Part of Acta Crystallographica Section D, p. 2267-2277, 2015

• DOI for Structure of AadA from Salmonella enterica: a monomeric aminoglycoside (3'')(9) adenyltransferase
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Minor Fitness Costs in an Experimental Model of Horizontal Gene Transfer in Bacteria

Knöppel, Anna; Lind, Peter A.; Lustig, Ulrika; Näsvall, Joakim et al.

Part of Molecular biology and evolution, p. 1220-1227, 2014

• DOI for Minor Fitness Costs in an Experimental Model of Horizontal Gene Transfer in Bacteria

High Fitness Costs and Instability of Gene Duplications Reduce Rates of Evolution of New Genes by Duplication-Divergence Mechanisms

Adler, Marlen; Anjum, Mehreen; Berg, Otto; Andersson, Dan I. et al.

Part of Molecular biology and evolution, p. 1526-1535, 2014

• DOI for High Fitness Costs and Instability of Gene Duplications Reduce Rates of Evolution of New Genes by Duplication-Divergence Mechanisms

Selection of Orphan Rhs Toxin Expression in Evolved Salmonella enterica Serovar Typhimurium

Koskiniemi, Sanna; Garza-Sanchez, Fernando; Sandegren, Linus; Webb, Julia S. et al.

Part of PLOS Genetics, 2014

• DOI for Selection of Orphan Rhs Toxin Expression in Evolved Salmonella enterica Serovar Typhimurium
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Resistance to beta-Lactam Antibiotics Conferred by Point Mutations in Penicillin-Binding Proteins PBP3, PBP4 and PBP6 in Salmonella enterica

Sun, Song; Selmer, Maria; Andersson, Dan I.

Part of PLOS ONE, 2014

• DOI for Resistance to beta-Lactam Antibiotics Conferred by Point Mutations in Penicillin-Binding Proteins PBP3, PBP4 and PBP6 in Salmonella enterica
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Selection of a multidrug resistance plasmid by sublethal levels of antibiotics and heavy metals

Gullberg, Erik; Albrecht, Lisa M; Karlsson, Christoffer; Sandegren, Linus et al.

Part of mBio, 2014

• DOI for Selection of a multidrug resistance plasmid by sublethal levels of antibiotics and heavy metals

Characterization of Resitant Mutants Points Towards Mechanism of Action of Cyclotides

Malik, Sohaib Zafar; Andersson, Dan I.; Göransson, Ulf

Part of Journal of Peptide Science, 2014

Evolution of Broad Spectrum beta-Lactam Resistance in an Engineered Metallo-beta-lactamase

Sun, Song; Zhang, Wei; Mannervik, Bengt; Andersson, Dan I.

Part of Journal of Biological Chemistry, p. 2314-2324, 2013

• DOI for Evolution of Broad Spectrum beta-Lactam Resistance in an Engineered Metallo-beta-lactamase

Fitness Costs of Synonymous Mutations in the rpsT Gene Can Be Compensated by Restoring mRNA Base Pairing

Lind, Peter A.; Andersson, Dan I.

Part of PLOS ONE, 2013

• DOI for Fitness Costs of Synonymous Mutations in the rpsT Gene Can Be Compensated by Restoring mRNA Base Pairing
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Pathoadaptive Mutations in Salmonella enterica Isolated after Serial Passage in Mice

Koskiniemi, Sanna; Gibbons, Henry S.; Sandegren, Linus; Anwar, Naeem et al.

Part of PLOS ONE, 2013

• DOI for Pathoadaptive Mutations in Salmonella enterica Isolated after Serial Passage in Mice
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Mechanisms and Fitness Costs of Resistance to Antimicrobial Peptides LL-37, CNY100HL and Wheat Germ Histones

Lofton Tomenius, Hava; Pränting, Maria; Thulin, Elisabeth; Andersson, Dan I.

Part of PLOS ONE, 2013

• DOI for Mechanisms and Fitness Costs of Resistance to Antimicrobial Peptides LL-37, CNY100HL and Wheat Germ Histones
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Lon protease inactivation, or translocation of the lon gene, potentiate bacterial evolution to antibiotic resistance

Nicoloff, Hervé; Andersson, Dan I.

Part of Molecular Microbiology, p. 1233-1248, 2013

• DOI for Lon protease inactivation, or translocation of the lon gene, potentiate bacterial evolution to antibiotic resistance

Mechanisms and fitness costs of tigecycline resistance in Escherichia coli

Linkevicius, Marius; Sandegren, Linus; Andersson, Dan I.

Part of Journal of Antimicrobial Chemotherapy, p. 2809-2819, 2013

• DOI for Mechanisms and fitness costs of tigecycline resistance in Escherichia coli

Influence of acquired β-lactamases on the evolution of spontaneous carbapenem resistance in Escherichia coli

Adler, Marlen; Anjum, Mehreen; Andersson, Dan I.; Sandegren, Linus

Part of Journal of Antimicrobial Chemotherapy, p. 51-59, 2013

• DOI for Influence of acquired β-lactamases on the evolution of spontaneous carbapenem resistance in Escherichia coli

Selection-driven genome reduction in bacteria

Koskiniemi, Sanna; Sun, Song; Berg, Otto; Andersson, Dan I.

Part of PLOS genetics, 2012

• DOI for Selection-driven genome reduction in bacteria
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Transfer of an Escherichia coli ST131 multiresistance cassette has created a Klebsiella pneumoniae-specific plasmid associated with a major nosocomial outbreak

Sandegren, Linus; Linkevicius, Marius; Lytsy, Birgitta; Åsa, Melhus et al.

Part of Journal of Antimicrobial Chemotherapy, p. 74-83, 2012

• DOI for Transfer of an Escherichia coli ST131 multiresistance cassette has created a Klebsiella pneumoniae-specific plasmid associated with a major nosocomial outbreak

Genome-Wide Detection of Spontaneous Chromosomal Rearrangements in Bacteria

Sun, Song; Ke, Rongqin; Hughes, Diarmaid; Nilsson, Mats et al.

Part of PLOS ONE, 2012

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Compensatory mutations in agrC partly restore fitness in vitro to peptide deformylase inhibitor-resistant Staphylococcus aureus

Zorzet, Anna; Andersen, Jytte Mark; Nilsson, Annika I; Møller, Niels Frimodt et al.

Part of Journal of Antimicrobial Chemotherapy, p. 1835-1842, 2012

• DOI for Compensatory mutations in agrC partly restore fitness in vitro to peptide deformylase inhibitor-resistant Staphylococcus aureus

Poxvirus Use a "Gene Accordion" to Tune Out Host Defenses

Roth, John R.; Andersson, Dan I.

Part of Cell, p. 671-672, 2012

• DOI for Poxvirus Use a "Gene Accordion" to Tune Out Host Defenses

Real-Time Evolution of New Genes by Innovation, Amplification, and Divergence

Näsvall, Joakim; Sun, Lei; Roth, John R.; Andersson, Dan I.

Part of Science, p. 384-387, 2012

• DOI for Real-Time Evolution of New Genes by Innovation, Amplification, and Divergence

Selection of resistance at lethal and non-lethal antibiotic concentrations

Hughes, Diarmaid; Andersson, Dan I

Part of Current Opinion in Microbiology, p. 555-560, 2012

• DOI for Selection of resistance at lethal and non-lethal antibiotic concentrations

Evolution of antibiotic resistance at non-lethal drug concentrations.

Andersson, Dan I; Hughes, Diarmaid

Part of Drug resistance updates, p. 162-172, 2012

• DOI for Evolution of antibiotic resistance at non-lethal drug concentrations.

Activation of cryptic aminoglycoside resistance in Salmonella enterica

Koskiniemi, Sanna; Pränting, Maria; Gullberg, Erik; Näsvall, Joakim et al.

Part of Molecular Microbiology, p. 1464-1478, 2011

• DOI for Activation of cryptic aminoglycoside resistance in Salmonella enterica

Selection of Resistant Bacteria at Very Low Antibiotic Concentrations

Gullberg, Erik; Cao, Sha; Berg, Otto G.; Ilbäck, Carolina et al.

Part of PLoS pathogens, 2011

• DOI for Selection of Resistant Bacteria at Very Low Antibiotic Concentrations

Activation of initiation factor 2 by ligands and mutations for rapid docking of ribosomal subunits

Pavlov, Michael Y.; Zorzet, Anna; Andersson, Dan I.; Ehrenberg, Måns

Part of EMBO Journal, p. 289-301, 2011

• DOI for Activation of initiation factor 2 by ligands and mutations for rapid docking of ribosomal subunits

Escape from growth restriction in small colony variants of Salmonella typhimurium by gene amplification and mutation

Pränting, Maria; Andersson, Dan I.

Part of Molecular Microbiology, p. 305-315, 2011

• DOI for Escape from growth restriction in small colony variants of Salmonella typhimurium by gene amplification and mutation

Evolving promiscuously

Andersson, Dan I.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 1199-1200, 2011

• DOI for Evolving promiscuously

Beyond serial passages: new methods for predicting the emergence of resistance to novel antibiotics

Luis Martinez, Jose; Baquero, Fernando; Andersson, Dan I.

Part of Current opinion in pharmacology (Print), p. 439-445, 2011

• DOI for Beyond serial passages: new methods for predicting the emergence of resistance to novel antibiotics

PEG-stabilized lipid disks as carriers for amphiphilic antimicrobial peptides

Zetterberg, Malin M.; Reijmar, Karin; Pränting, Maria; Engström, Åke et al.

Part of Journal of Controlled Release, p. 323-328, 2011

• DOI for PEG-stabilized lipid disks as carriers for amphiphilic antimicrobial peptides
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Dynamics of Antibiotic Resistant Mycobacterium tuberculosis during Long-Term Infection and Antibiotic Treatment

Mariam, Solomon H.; Werngren, Jim; Aronsson, Joakim; Hoffner, Sven et al.

Part of PLOS ONE, 2011

Compensatory gene amplification restores fitness after inter-species gene replacements

Lind, Peter A; Tobin, Christina; Berg, Otto G; Kurland, Charles G et al.

Part of Molecular Microbiology, p. 1078-1089, 2010

• DOI for Compensatory gene amplification restores fitness after inter-species gene replacements

Mutational robustness of ribosomal protein genes

Lind, Peter A.; Berg, Otto G.; Andersson, Dan I

Part of Science, p. 825-827, 2010

• DOI for Mutational robustness of ribosomal protein genes

The cyclotide cycloviolacin O2 from Viola odorata has potent bactericidal activity against Gram-negative bacteria

Pränting, Maria; Lööv, Camilla; Burman, Robert; Göransson, Ulf et al.

Part of Journal of Antimicrobial Chemotherapy, p. 1964-1971, 2010

• DOI for The cyclotide cycloviolacin O2 from Viola odorata has potent bactericidal activity against Gram-negative bacteria

Ribosomes lacking protein S20 are defective in mRNA binding and subunit association

Tobin, Christina; Mandava, Chandra Sekhar; Ehrenberg, Måns; Andersson, Dan I et al.

Part of Journal of Molecular Biology, p. 767-776, 2010

• DOI for Ribosomes lacking protein S20 are defective in mRNA binding and subunit association

Error-prone initiation factor 2 mutations reduce the fitness cost of antibiotic resistance

Zorzet, Anna; Pavlov, Michael; Nilsson, Annika; Ehrenberg, Måns et al.

Part of Molecular Microbiology, p. 1299-1313, 2010

• DOI for Error-prone initiation factor 2 mutations reduce the fitness cost of antibiotic resistance
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Mechanisms and physiological effects of protamine resistance in Salmonella enterica serovar Typhimurium LT2

Pränting, Maria; Andersson, Dan I

Part of Journal of Antimicrobial Chemotherapy, p. 876-887, 2010

• DOI for Mechanisms and physiological effects of protamine resistance in Salmonella enterica serovar Typhimurium LT2

Rates and Mechanisms of Resistance Development in Mycobacterium tuberculosis to a Novel Diarylquinoline ATP Synthase Inhibitor

Huitric, E.; Verhasselt, P.; Koul, A.; Andries, K. et al.

Part of Antimicrobial Agents and Chemotherapy, p. 1022-1028, 2010

• DOI for Rates and Mechanisms of Resistance Development in Mycobacterium tuberculosis to a Novel Diarylquinoline ATP Synthase Inhibitor

Amplification of the Gene for Isoleucyl-tRNA Synthetase Facilitates Adaptation to the Fitness Cost of Mupirocin Resistance in Salmonella enterica

Paulander, Wilhelm; Andersson, Dan I.; Maisnier-Patin, Sophie

Part of Genetics, p. 305-312, 2010

• DOI for Amplification of the Gene for Isoleucyl-tRNA Synthetase Facilitates Adaptation to the Fitness Cost of Mupirocin Resistance in Salmonella enterica

The Tandem Inversion Duplication in Salmonella enterica: Selection Drives Unstable Precursors to Final Mutation Types

Kugelberg, Elisabeth; Kofoid, Eric; Andersson, Dan I.; Lu, Yong et al.

Part of Genetics, p. 65-80, 2010

• DOI for The Tandem Inversion Duplication in Salmonella enterica: Selection Drives Unstable Precursors to Final Mutation Types

Effect of the translesion DNA polymerases, endonucleases and RpoS on mutation rates in Salmonella typhimurium

Koskiniemi, Sanna; Hughes, Diarmaid; Andersson, Dan I

Part of Genetics, p. 783-795, 2010

• DOI for Effect of the translesion DNA polymerases, endonucleases and RpoS on mutation rates in Salmonella typhimurium

Little evidence for reversibility of trimethoprim resistance after a drastic reduction in trimethoprim use

Sundqvist, Martin; Geli, Patricia; Andersson, Dan I.; Sjölund-Karlsson, M. et al.

Part of Journal of Antimicrobial Chemotherapy, p. 350-360, 2010

• DOI for Little evidence for reversibility of trimethoprim resistance after a drastic reduction in trimethoprim use

Directed mutagenesis of Mycobacterium smegmatis 16S rRNA to reconstruct the in-vivo evolution of aminoglycoside resistance in Mycobacterium tuberculosis

Shcherbakov, Dmitri; Akbergenov, Rashid; Matt, Tanja; Sander, Peter et al.

Part of Molecular Microbiology, p. 830-40, 2010

• DOI for Directed mutagenesis of Mycobacterium smegmatis 16S rRNA to reconstruct the in-vivo evolution of aminoglycoside resistance in Mycobacterium tuberculosis

Genetic analysis of colistin resistance in Salmonella enterica serovar Typhimurium

Sun, Song; Negrea, Aurel; Rhen, Mikael; Andersson, Dan I

Part of Antimicrobial Agents and Chemotherapy, p. 2298-2305, 2009

• DOI for Genetic analysis of colistin resistance in Salmonella enterica serovar Typhimurium

Contribution of gene amplification to evolution of increased antibiotic resistance in Salmonella typhimurium

Sun, Song; Berg, Otto G; Andersson, Dan I; Roth, John R

Part of Genetics, p. 1183-1195, 2009

• DOI for Contribution of gene amplification to evolution of increased antibiotic resistance in Salmonella typhimurium

Evolution of new gene functions: simulation and analysis of the amplification model.

Pettersson, Mats E.; Sun, Song; Andersson, Dan I.; Berg, Otto G

Part of Genetica, p. 309-324, 2009

• DOI for Evolution of new gene functions: simulation and analysis of the amplification model.

A multi-type branching model with varying environment for bacterial dynamics with postantibiotic effect

Geli, Patricia; Andersson, Mikael; Svensson, Åke; Andersson, Dan I

Part of Journal of Theoretical Biology, p. 58-64, 2009

• DOI for A multi-type branching model with varying environment for bacterial dynamics with postantibiotic effect

The fitness cost of streptomycin resistance depends on rpsL mutation, carbon source and RpoS (sigmaS)

Paulander, Wilhelm; Maisnier-Patin, Sophie; Andersson, Dan I

Part of Genetics, p. 539-546, 2009

• DOI for The fitness cost of streptomycin resistance depends on rpsL mutation, carbon source and RpoS (sigmaS)

Translesion DNA polymerases are required for spontaneous deletion formation in Salmonella typhimurium

Koskiniemi, Sanna; Andersson, Dan I

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 10248-10253, 2009

• DOI for Translesion DNA polymerases are required for spontaneous deletion formation in Salmonella typhimurium

The first major extended-spectrum beta-lactamase outbreak in Scandinavia was caused by clonal spread of a multiresistant Klebsiella pneumoniae producing CTX-M-15

Lytsy, Birgitta; Sandegren, Linus; Tano, Eva; Torell, Erik et al.

Part of Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS), p. 302-8, 2008

• DOI for The first major extended-spectrum beta-lactamase outbreak in Scandinavia was caused by clonal spread of a multiresistant Klebsiella pneumoniae producing CTX-M-15

Whole-genome mutational biases in bacteria

Lind, Peter A.; Andersson, Dan I.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 17878-83, 2008

• DOI for Whole-genome mutational biases in bacteria

Mechanism and fitness costs of PR-39 resistance in Salmonella enterica serovar Typhimurium LT2

Pränting, Maria; Negrea, Aurel; Rhen, Mikael; Andersson, Dan I

Part of Antimicrobial Agents and Chemotherapy, p. 2734-2741, 2008

• DOI for Mechanism and fitness costs of PR-39 resistance in Salmonella enterica serovar Typhimurium LT2

Nitrofurantoin resistance mechanism and fitness cost in Escherichia coli

Sandegren, Linus; Lindqvist, Anton; Kahlmeter, Gunnar; Andersson, Dan I

Part of Journal of Antimicrobial Chemotherapy, p. 495-503, 2008

• DOI for Nitrofurantoin resistance mechanism and fitness cost in Escherichia coli

Restored fitness leads to long-term persistence of resistant Bacteroides strains in the human intestine

Löfmark, Sonja; Jernberg, Cecilia; Billström, Hanna; Andersson, Dan I. et al.

Part of Anaerobe, p. 157-160, 2008

• DOI for Restored fitness leads to long-term persistence of resistant Bacteroides strains in the human intestine

Shrinking Bacterial Genomes: Former skeptics recognize that the genomes of microbial parasites and symbionts are subject to dynamic downsizing

Andersson, Dan I

Part of Microbe, p. 124-130, 2008

Caenorhabditis elegans as a model to determine fitness of antibiotic-resistant Salmonella enterica serovar typhimurium

Paulander, Wilhelm; Pennhag, Alexandra; Andersson, Dan I.; Maisnier-Patin, Sophie

Part of Antimicrobial Agents and Chemotherapy, p. 766-769, 2007

• DOI for Caenorhabditis elegans as a model to determine fitness of antibiotic-resistant Salmonella enterica serovar typhimurium

Antibiotic treatment in vitro of phenotypically tolerant bacterial populations

Wiuff, Camilla; Andersson, Dan I.

Part of Journal of Antimicrobial Chemotherapy, p. 254-263, 2007

• DOI for Antibiotic treatment in vitro of phenotypically tolerant bacterial populations

Ohno's dilemma: evolution of new genes under continuous selection

Bergthorsson, Ulfar; Andersson, Dan I.; Roth, John R.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 17004-17009, 2007

• DOI for Ohno's dilemma: evolution of new genes under continuous selection

Multiple mechanisms to ameliorate the fitness burden of mupirocin resistance in Salmonella typhimurium

Paulander, Wilhelm; Maisnier-Patin, Sophie; Andersson, Dan I.

Part of Molecular Microbiology, p. 1038-1048, 2007

• DOI for Multiple mechanisms to ameliorate the fitness burden of mupirocin resistance in Salmonella typhimurium

Compensatory Evolution Reveals Functional Interactions between Ribosomal Proteins S12, L14 and L19

Maisnier-Patin, S; Paulander, W; Pennhag, A; Andersson, Dan I.

Part of Journal of Molecular Biology, p. 207-215, 2007

• DOI for Compensatory Evolution Reveals Functional Interactions between Ribosomal Proteins S12, L14 and L19

Reducing the fitness cost of antibiotic resistance by amplification of initiator tRNA genes

Nilsson, Annika I.; Zorzet, Anna; Kanth, Anna; Dahlström, Sabina et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 6976-6981, 2006

• DOI for Reducing the fitness cost of antibiotic resistance by amplification of initiator tRNA genes

Multiple pathways of selected gene amplification during adaptive mutation

Kugelberg, Elisabeth; Kofoid, Eric; Reams, Andrew B.; Andersson, Dan I. et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 17319-17324, 2006

• DOI for Multiple pathways of selected gene amplification during adaptive mutation

The biological cost of mutational antibiotic resistance: any practical conclusions?

Andersson, Dan I

Part of Curr Opin Microbiol, p. 461-5, 2006

Origin of mutations under selection: the adaptive mutation controversy.

Roth, John R; Kugelberg, Elisabeth; Reams, Andrew B; Kofoid, Eric et al.

Part of Annu Rev Microbiol, p. 477-501, 2006

Genomic buffering mitigates the effects of deleterious mutations in bacteria

Maisnier-Patin, Sophie; Roth, John; Fredriksson, Åsa; Nyström, Thomas et al.

Part of Nature Genetics, p. 1376-1379, 2005

• DOI for Genomic buffering mitigates the effects of deleterious mutations in bacteria

Establishment of a superficial skin infection model in mice by using Staphylococcus aureus and Streptococcus pyogenes

Kugelberg, Elisabeth; Norström, Tobias; Petersen, Thomas K; Duvold, Tore et al.

Part of Antimicrobial Agents and Chemotherapy, p. 3435-3441, 2005

• DOI for Establishment of a superficial skin infection model in mice by using Staphylococcus aureus and Streptococcus pyogenes

Slow genetic divergence of Helicobacter pylori strains during long-term colonization

Lundin, Annelie; Björkholm, Britta; Kupershmidt, Ilya; Unemo, Magnus et al.

Part of Infection and Immunity, p. 4818-4822, 2005

• DOI for Slow genetic divergence of Helicobacter pylori strains during long-term colonization

Persistence of resistant Staphylococcus epidermidis after single course of clarithromycin

Sjölund, Maria; Tano, Eva; Blaser, Martin J; Andersson, Dan I et al.

Part of Emerging Infectious Diseases, p. 1389-1393, 2005

Reduction of the fitness burden of quinolone resistance in Pseudomonas aeruginosa

Kugelberg, Elisabeth; Löfmark, Sonja; Wretlind, Bengt; Andersson, Dan I

Part of Journal of Antimicrobial Chemotherapy, p. 22-30, 2005

• DOI for Reduction of the fitness burden of quinolone resistance in Pseudomonas aeruginosa

Pharmacodynamic model to describe the concentration-dependent selection of cefotaxime-resistant Escherichia coli

Olofsson, Sara K.; Geli, Patricia; Andersson, Dan I.; Cars, Otto

Part of Antimicrobial Agents and Chemotherapy, p. 5081-5091, 2005

Bacterial genome size reduction by experimental evolution

Nilsson, A I; Koskiniemi, Sanna; Eriksson, S; Kugelberg, E et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 12112-12116, 2005

• DOI for Bacterial genome size reduction by experimental evolution

Drug resistance and fitness in Mycobacterium tuberculosis infection.

Bottger, Erik C; Pletschette, Michel; Andersson, Dan

Part of J Infect Dis, p. 823-4; author reply 824, 2005

Pharmacodynamic model to describe the concentration-dependent selection of cefotaxime-resistant Escherichia coli.

Olofsson, Sara K; Geli, Patricia; Andersson, Dan I; Cars, Otto

Part of Antimicrob Agents Chemother, p. 5081-91, 2005

Adaptive mutation: how growth under selection stimulates Lac(+) reversion by increasing target copy number

Roth, John R; Andersson, Dan I

Part of Journal of Bacteriology, p. 4855-4860, 2004

• DOI for Adaptive mutation: how growth under selection stimulates Lac(+) reversion by increasing target copy number

Rebuttal: adaptive mutation in Escherichia coli (Foster)

Roth, John R; Andersson, Dan I

Part of Journal of Bacteriology, p. 4854-4854, 2004

• DOI for Rebuttal: adaptive mutation in Escherichia coli (Foster)

Rebuttal: adaptive point mutation (Rosenberg and Hastings)

Roth, John R; Andersson, Dan I

Part of Journal of Bacteriology, p. 4844, 2004

• DOI for Rebuttal: adaptive point mutation (Rosenberg and Hastings)

Experimental adaptation of Salmonella typhimurium to mice

Nilsson, Annika; Kugelberg, Elisabeth; Berg, Otto; Andersson, Dan I.

Part of Genetics, p. 1119-1130, 2004

• DOI for Experimental adaptation of Salmonella typhimurium to mice

Effect of rpoB mutations conferring rifampin resistance on fitness of Mycobacterium tuberculosis

Mariam, Deneke H; Mengistu, Yohannes; Hoffner, Sven E; Andersson, Dan I

Part of Antimicrobial Agents and Chemotherapy, p. 1289-1294, 2004

Adaptation to the deleterious effects of antimicrobial drug resistance mutations by compensatory evolution

Maisnier-Patin, Sophie; Andersson, Dan I

Part of Research in Microbiology, p. 360-369, 2004

• DOI for Adaptation to the deleterious effects of antimicrobial drug resistance mutations by compensatory evolution

Amplification-mutagenesis: how growth under selection contributes to the origin of genetic diversity and explains the phenomenon of adaptive mutation

Roth, John R; Andersson, Dan I

Part of Research in Microbiology, p. 342-351, 2004

• DOI for Amplification-mutagenesis: how growth under selection contributes to the origin of genetic diversity and explains the phenomenon of adaptive mutation

Polymorphic mutation frequencies in Escherichia coli: emergence of weak mutators in clinical isolates

Baquero, María-Rosario; Nilsson, Annika I; Turrientes, María del Carmen; Sandvang, Dorthe et al.

Part of Journal of Bacteriology, p. 5538-5542, 2004

• DOI for Polymorphic mutation frequencies in Escherichia coli: emergence of weak mutators in clinical isolates

The amplification model for adaptive mutation: simulations and analysis

Pettersson, M.; Andersson, Dan I; Roth, J R; Berg, O G

Part of Genetics, p. 1105-1115, 2004

• DOI for The amplification model for adaptive mutation: simulations and analysis

Comparative proteome analysis of Mycobacterium tuberculosis grown under aerobic and anaerobic conditions

Starck, Joakim; Källenius, Gunilla; Marklund, Britt-Inger; Andersson, Dan I et al.

Part of Microbiology, p. 3821-3829, 2004

• DOI for Comparative proteome analysis of Mycobacterium tuberculosis grown under aerobic and anaerobic conditions

The NudA protein in the gastric pathogen Helicobacter pylori is an ubiquitous and constitutively expressed dinucleoside polyphosphate hydrolase

Lundin, Annelie; Nilsson, Christina; Gerhard, Markus; Andersson, Dan I et al.

Part of Journal of Biological Chemistry, p. 12574-12578, 2003

• DOI for The NudA protein in the gastric pathogen Helicobacter pylori is an ubiquitous and constitutively expressed dinucleoside polyphosphate hydrolase

Long-term persistence of resistant Enterococcus species after antibiotics to eradicate Helicobacter pylori

Sjölund, Maria; Wreiber, Karin; Andersson, Dan I; Blaser, Martin J et al.

Part of Annals of Internal Medicine, p. 483-487, 2003

Bacteria with increased mutation frequency and antibiotic resistance are enriched in the commensal flora of patients with high antibiotic usage

Gustafsson, Ingegerd; Sjölund, Maria; Torell, Erik; Johannesson, Marie et al.

Part of Journal of Antimicrobial Chemotherapy, p. 645-650, 2003

• DOI for Bacteria with increased mutation frequency and antibiotic resistance are enriched in the commensal flora of patients with high antibiotic usage

Long-term persistence of resistant Enterococcus species after antibiotics to eradicate Helicobacter pylori

Sjölund, Maria; Wreiber, Karin; Andersson, Dan I.; Blaser, Martin J. et al.

Part of Ann Intern Med, p. 483-7, 2003

Mutation frequency and biological cost of resistance in Helicobacter pylori.

Björkholm, Britta; Sjölund, Maria; Falk, Per G.; Berg, Otto G. et al.

Part of Proc Natl Acad Sci U S A, p. 14607-12, 2001

Novel ribosomal mutations affecting translational accuracy, antibiotic resistance and virulence of Salmonella typhimurium

Björkman, Johanna; Samuelsson, Patrik; Andersson, Dan I.; Hughes, Diarmaid

Part of Molecular Microbiology, p. 53-58, 1999

• DOI for Novel ribosomal mutations affecting translational accuracy, antibiotic resistance and virulence of Salmonella typhimurium

Muller's ratchet decreases fitness of a DNA-based microbe

Andersson, Dan I; Hughes, Diarmaid

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 906-907, 1996

Low conservation of antibiotic interactions between and within Gram-negative bacterial species

Tang, Po-Cheng; Sánchez-Hevia, Dione; Westhoff, Sanne; Fatsis-Kavalopoulos, Nikolaos et al.

Part of PLoS biology

The physiology and genetics of bacterial responses to antibiotic combinations

Roemhild, Roderich; Bollenbach, Tobias; Andersson, Dan I.

Part of Nature Reviews Microbiology, p. 478-490, 2022

• DOI for The physiology and genetics of bacterial responses to antibiotic combinations

Antibiotic resistance: turning evolutionary principles into clinical reality

Andersson, Dan I.; Balaban, Nathalie Q.; Baquero, Fernando; Courvalin, Patrice et al.

Part of FEMS Microbiology Reviews, p. 171-188, 2020

• DOI for Antibiotic resistance: turning evolutionary principles into clinical reality

Mechanisms and clinical relevance of bacterial heteroresistance

Andersson, Dan I; Nicoloff, Hervé; Hjort, Karin

Part of Nature Reviews Microbiology, p. 479-496, 2019

• DOI for Mechanisms and clinical relevance of bacterial heteroresistance

Definitions and guidelines for research on antibiotic persistence

Balaban, Nathalie Q.; Helaine, Sophie; Lewis, Kim; Ackermann, Martin et al.

Part of Nature Reviews Microbiology, p. 441-448, 2019

• DOI for Definitions and guidelines for research on antibiotic persistence
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Prediction of antibiotic resistance: time for a new preclinical paradigm?

Sommer, Morten O. A.; Munck, Christian; Toft-Kehler, Rasmus Vendler; Andersson, Dan I

Part of Nature Reviews Microbiology, p. 688-695, 2017

• DOI for Prediction of antibiotic resistance: time for a new preclinical paradigm?
• Download full text (pdf) of Prediction of antibiotic resistance: time for a new preclinical paradigm?

Evolutionary Trajectories to Antibiotic Resistance

Hughes, Diarmaid; Andersson, Dan I

Part of Annual Review of Microbiology, p. 579-596, 2017

• DOI for Evolutionary Trajectories to Antibiotic Resistance

Environmental and genetic modulation of the phenotypic expression of antibiotic resistance

Hughes, Diarmaid; Andersson, Dan I

Part of FEMS Microbiology Reviews, p. 374-391, 2017

• DOI for Environmental and genetic modulation of the phenotypic expression of antibiotic resistance

Mechanisms and consequences of bacterial resistance to antimicrobial peptides

Andersson, Dan I.; Hughes, Diarmaid; Kubicek-Sutherland, Jessica Z.

Part of Drug resistance updates, p. 43-57, 2016

• DOI for Mechanisms and consequences of bacterial resistance to antimicrobial peptides
• Download full text (pdf) of Mechanisms and consequences of bacterial resistance to antimicrobial peptides

Evolution of New Functions De Novo and from Preexisting Genes

Andersson, Dan I.; Jerlström-Hultqvist, Jon; Näsvall, Joakim

Part of Cold Spring Harbor Perspectives in Biology, 2015

• DOI for Evolution of New Functions De Novo and from Preexisting Genes

Evolutionary consequences of drug resistance: shared principles across diverse targets and organisms

Hughes, Diarmaid; Andersson, Dan I.

Part of Nature reviews genetics, p. 459-471, 2015

• DOI for Evolutionary consequences of drug resistance: shared principles across diverse targets and organisms

Improving predictions of the risk of resistance development against new and old antibiotics

Andersson, Dan I.

Part of Clinical Microbiology and Infection, p. 894-898, 2015

• DOI for Improving predictions of the risk of resistance development against new and old antibiotics

Microbiological effects of sublethal levels of antibiotics

Andersson, Dan I.; Hughes, Diarmaid

Part of Nature Reviews Microbiology, p. 465-478, 2014

• DOI for Microbiological effects of sublethal levels of antibiotics

The origin of mutants under selection: Interactions of mutation, growth and selection

Andersson, Dan I.; Hughes, Diarmaid; Roth, John R

Part of EcoSal Plus, 2011

• DOI for The origin of mutants under selection: Interactions of mutation, growth and selection

Persistence of antibiotic resistance in bacterial populations

Andersson, Dan I.; Hughes, Diarmaid

Part of FEMS Microbiology Reviews, p. 901-911, 2011

• DOI for Persistence of antibiotic resistance in bacterial populations

Biological roles of translesion synthesis DNA polymerases in eubacteria

Andersson, Dan I.; Koskiniemi, Sanna; Hughes, Diarmaid

Part of Molecular Microbiology, p. 540-548, 2010

• DOI for Biological roles of translesion synthesis DNA polymerases in eubacteria

Antibiotic resistance and its cost: is it possible to reverse resistance?

Andersson, Dan I.; Hughes, Diarmaid

Part of Nature Reviews Microbiology, p. 260-271, 2010

• DOI for Antibiotic resistance and its cost: is it possible to reverse resistance?

Gene amplification and adaptive evolution in bacteria

Andersson, Dan I.; Hughes, Diarmaid

Part of Annual Review of Genetics, p. 167-195, 2009

• DOI for Gene amplification and adaptive evolution in bacteria

Bacterial gene amplification: implications for the evolution of antibiotic resistance

Sandegren, Linus; Andersson, Dan I.

Part of Nature Reviews Microbiology, p. 578-588, 2009

• DOI for Bacterial gene amplification: implications for the evolution of antibiotic resistance

Predicting antibiotic resistance

Martínez, José L.; Baquero, Fernando; Andersson, Dan I.

Part of Nature Reviews Microbiology, p. 958-965, 2007

• DOI for Predicting antibiotic resistance

Adventures with mutation and selection in beehive and cow country

Hughes, Diarmaid; Andersson, Dan I

Part of The Lure of Bacterial Genetics, p. 245-253, ASM Press, 2010

Effects of antibiotic resistance on bacterial fitness, virulence and transmission

Andersson, Dan I.; Hughes, Diarmaid

Part of Evolutionary biology of bacterial and fungal pathogens, p. 307-318, ASM Press, 2008

The Biological Cost of Antibiotic resistance

Andersson, Dan I; Maisner Patin, Sophie; Nilsson, Annika; Kugelberg, Elisabeth

Part of Enzyme-Mediated Resistance to Antibiotics, p. 339-348, 2007

Droplet microfluidics with image texture-based detection of bacterial heteroresistance in isolated from blood stream infections

Agnihotri, Sagar Narhari; Fatsis-Kavalopoulos, Nikos; Vikdahl, Emma; Andersson, Dan I. et al.

2025

Investigation of linoleic acid as an antibacterial additive in bone cement

Hong, Linglu; Hjort, Karin; Andersson, Dan I.; Persson, Cecilia

2024

Antibiofilm Properties of Linoleic Acid-loaded Bone Cement with and without Gentamicin

Hong, Linglu; Hjort, Karin; Persson, Cecilia; Andersson, Dan I.

Part of 33rd Annual Conference of the European Society for Biomaterials, p. 46-46, 2023

Impact of the pan-genome of Escherichia coli on the potential for de novo antibiotic resistance evolution: Supplemental material: Figure S1

Jagdmann, Jennifer; Andersson, Dan I.; Nicoloff, Hervé

2022

Impact of the pan-genome of Escherichia coli on the potential for de novo antibiotic resistance evolution: Supplemental material: Table S1.

Jagdmann, Jennifer; Andersson, Dan I.; Nicoloff, Hervé

2022

Impact of the genetic background on plasmid-borne antibiotic resistance: Supplemental information: Table S6

Jagdmann, Jennifer; Nicoloff, Hervé; Andersson, Dan I.

2022

Clonal spread and antibiotic selection of a mutation preventing the evolution of high-level resistance: Supporting information: S8 Table

Jagdmann, Jennifer; Nicoloff, Hervé; Andersson, Dan I.

2022

Impact of the genetic background on plasmid-borne antibiotic resistance: Supplemental information: Table S1

Jagdmann, Jennifer; Nicoloff, Hervé; Andersson, Dan I.

2022

Impact of the genetic background on plasmid-borne antibiotic resistance: Supplemental information: Table S7

Jagdmann, Jennifer; Nicoloff, Hervé; Andersson, Dan I.

2022

Clonal spread and antibiotic selection of a mutation preventing the evolution of high-level resistance: Supporting information: S11 Table

Jagdmann, Jennifer; Nicoloff, Hervé; Andersson, Dan I.

2022

Clonal spread and antibiotic selection of a mutation preventing the evolution of high-level resistance: Supporting information: S4 Table

Jagdmann, Jennifer; Nicoloff, Hervé; Andersson, Dan I.

2022

Clonal spread and antibiotic selection of a mutation preventing the evolution of high-level resistance: Supporting information: S1 Data

Jagdmann, Jennifer; Nicoloff, Hervé; Andersson, Dan I.

2022

Clonal spread and antibiotic selection of a mutation preventing the evolution of high-level resistance: Supporting information: S2 Table

Jagdmann, Jennifer; Nicoloff, Hervé; Andersson, Dan I.

2022

Clonal spread and antibiotic selection of a mutation preventing the evolution of high-level resistance: Supporting information: S10 Table

Jagdmann, Jennifer; Nicoloff, Hervé; Andersson, Dan I.

2022

Impact of the genetic background on plasmid-borne antibiotic resistance: Supplemental information: Table S2

Jagdmann, Jennifer; Nicoloff, Hervé; Andersson, Dan I.

2022

An oxidative stress-induced bypass mechanism confers antibiotic resistance in Escherichia coli

Thulin, Elisabeth; Andersson, Dan I

Compensatory evolution in mecillinam resistant Escherichia coli

Thulin, Elisabeth; Knopp, Michael; Ekstrand, Emelie; Andersson, Dan I

Fitness of antibiotic resistant Staphylococcus epidermidis assessed by competition on skin of human volunteers

Gustafsson, Ingegerd; Cars, Otto; Andersson, Dan I.

Fitness of Antibiotic-Resistant Staphylococcus epidermidis

Sjölund, Maria; Tano, Eva; Blaser, Martin J.; Andersson, Dan I. et al.

Extensive sharing and transmission of intestinal bacteria between couples before and after antibiotic treatment

Olofsson, Sara K.; Andersson, Dan I.; Cars, Otto

Initiation factor 2 mutants promoting fast joining of ribosomal subunits in the absence of initiator tRNA or GTP

Pavlov, Michael; Zorzet, Anna; Andersson, Dan I; Ehrenberg, Måns

Compensatory evolution restores fitness to actinonin-resistant Staphylococcus aureus

Zorzet, Anna; Nilsson, Annika; Andersson, Dan I

Fitness constraints on horizontal gene transfer

Lind, Peter A; Andersson, Dan I

Mutation in the Copper-Induced sil Operon Enables High-Level Silver Resistance and Silver Facilitated Co-Selection of Multidrug Resistance Plasmid

Albrecht, Lisa M; Sandegren, Linus; Andersson, Dan

Potentiation of the Selective Effect of Antibiotics by Metal Ions

Albrecht, Lisa M; Andersson, Dan I

Cross-Resistance to Antibiotics After Exposure to Qaternary Ammonium Compounds

Albrecht, Lisa M; Andersson, Dan I

Experimental evolution of novel metabolic capabilities in Salmonella enterica

Warsi, Omar M.; Lundin, Erik; Lustig, Ulrika; Näsvall, Joakim et al.

Functional trade-offs during evolution of new functions in the HisA-TrpF system

Lundin, Erik; Näsvall, Joakim; Andersson, Dan I

Spread of resistance plasmids and selection of resistant bacteria among Mallards exposed to sub-inhibitory concentrations of antibiotics in their water environment

Atterby, Clara; Nykvist, Marie; Lustig, Ulrika; Andersson, Dan I et al.

Structure of a phage-encoded SAMase enzyme provides insights in substrate binding and mechanism

Guo, Xiaohu; Söderholm, Annika; Kanchugal Puttaswamy, Sandesh; Isaksen, Geir et al.

The pan-genome of Escherichia coli strongly affects the potential for de novo antibiotic resistance evolution

Jagdmann, Jennifer; Guliaev, Andrei; Andersson, Dan I.; Nicoloff, Hervé

Impact of the bacterial genetic background on plasmid-borne antibiotic resistance

Jagdmann, Jennifer; Saubi Puignau, Cristina; Andersson, Dan I.; Nicoloff, Hervé

Host-specific determinants of Legionella pneumophila virulence passaged in single hosts and in alternation

Moreno, Anaísa B.; Paranjape, Kiran; Kay, Elisabeth; Dobre Lereanu, Christian et al.

Mutations that alter the synergistic interaction of tetracycline and spectinomycin in Escherichia coli

Tang, Po-Cheng; Valdaliso, Eunate; Westhoff, Sanne; Sánchez-Hevia, Dione L. et al.

Structure of a phage-encoded SAM hydrolase enzyme provides insights in substrate binding and catalysis

Söderholm, Annika; Selmer, Maria; Guo, Xiaohu; Kanchugal Puttaswamy, Sandesh et al.

Ribosomal protein L1 is required for balanced formation of ribosomal subunits

Tobin, Christina; Nord, Stefan; Wikström, P. Mikael; Näsvall, Joakim et al.

Prevalence, misclassification, and clinical consequences of the heteroresistant phenotype in Escherichia coli bloodstream infections in patients in Uppsala, Sweden: a retrospective cohort study

Heyman, Gabriel; Jonsson, Sofia; Fatsis-Kavalopoulos, Nikos; Hjort, Karin et al.

Part of The Lancet Microbe, 2025

• DOI for Prevalence, misclassification, and clinical consequences of the heteroresistant phenotype in Escherichia coli bloodstream infections in patients in Uppsala, Sweden: a retrospective cohort study
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The dynamic distribution of genetic tandem amplifications in a heteroresistant Escherichia coli population revealed by ultra-deep long read sequencing: Appendix files

Jonsson, Sofia; Guliaev, Andrei; Berryhill, Brandon A.; Andersson, Dan I. et al.

2025