Staffan Svärd

Host range expansion of asexual parasite can be explained by loss of adaptions in Muller's Ratchet

Tichkule, Swapnil; Van Oosterhout, Cock; Caccio, Simone M.; Weisz, Filip et al.

Part of Nature Communications, 2025

• DOI for Host range expansion of asexual parasite can be explained by loss of adaptions in Muller's Ratchet
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The expanded genome of Hexamita inflata, a free-living diplomonad

Akdeniz, Zeynep; Havelka, Michal; Stoklasa, Michal; Jiménez-González, Alejandro et al.

Part of Scientific Data, 2025

• DOI for The expanded genome of Hexamita inflata, a free-living diplomonad
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Occurrence of intestinal parasites and bacteria, with the emphasis on Giardia intestinalis in children under 5 years old in Magude village, Maputo, Mozambique

Casmo, Veronica; Noormahomed, Emilia; Knörr, Livia; Lebbad, Marianne et al.

2024

Tetramerization of deoxyadenosine kinase meets the demands of a DNA replication substrate challenge in Giardia intestinalis

Ranjbarian, Farahnaz; Rafie, Karim; Shankar, Kasturika; Krakovka, Sascha et al.

Part of Nucleic Acids Research, p. 14061-14076, 2024

• DOI for Tetramerization of deoxyadenosine kinase meets the demands of a DNA replication substrate challenge in Giardia intestinalis
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Gene co-expression network analysis reveal core responsive genes in Parascaris univalens tissues following ivermectin exposure

Dube, Faruk; Delhomme, Nicolas; Martin, Frida; Hinas, Andrea et al.

Part of PLOS ONE, 2024

• DOI for Gene co-expression network analysis reveal core responsive genes in Parascaris univalens tissues following ivermectin exposure
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Host range expansion of asexual parasite can be explained by loss of adaptions in Muller's Ratchet

Tichkule, Swapnil; Van Oosterhout, Cock; Caccio, Simone M.; Weisz, Filip et al.

Part of Nature Communications, 2025

• DOI for Host range expansion of asexual parasite can be explained by loss of adaptions in Muller's Ratchet
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The expanded genome of Hexamita inflata, a free-living diplomonad

Akdeniz, Zeynep; Havelka, Michal; Stoklasa, Michal; Jiménez-González, Alejandro et al.

Part of Scientific Data, 2025

• DOI for The expanded genome of Hexamita inflata, a free-living diplomonad
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Tetramerization of deoxyadenosine kinase meets the demands of a DNA replication substrate challenge in Giardia intestinalis

Ranjbarian, Farahnaz; Rafie, Karim; Shankar, Kasturika; Krakovka, Sascha et al.

Part of Nucleic Acids Research, p. 14061-14076, 2024

• DOI for Tetramerization of deoxyadenosine kinase meets the demands of a DNA replication substrate challenge in Giardia intestinalis
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Gene co-expression network analysis reveal core responsive genes in Parascaris univalens tissues following ivermectin exposure

Dube, Faruk; Delhomme, Nicolas; Martin, Frida; Hinas, Andrea et al.

Part of PLOS ONE, 2024

• DOI for Gene co-expression network analysis reveal core responsive genes in Parascaris univalens tissues following ivermectin exposure
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Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis

Majumdar, Soneya; Emmerich, Andrew G; Krakovka, Sascha; Mandava, Chandra Sekhar et al.

Part of Nucleic Acids Research, p. 3436-3451, 2023

• DOI for Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis
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Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain

Dube, Faruk; Hinas, Andrea; Delhomme, Nicolas; Åbrink, Magnus et al.

Part of PLOS ONE, 2023

• DOI for Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain
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Adaptation of the late ISC pathway in the anaerobic mitochondrial organelles of Giardia intestinalis

Motyckova, Alzbeta; Voleman, Lubos; Najdrova, Vladimira; Arbonova, Lenka et al.

Part of PLoS Pathogens, 2023

• DOI for Adaptation of the late ISC pathway in the anaerobic mitochondrial organelles of Giardia intestinalis
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Transcriptomic analysis of albendazole resistance in human diarrheal parasite Giardia duodenalis

Su, Qiao; Baker, Louise; Emery, Samantha; Balan, Balu et al.

Part of International Journal for Parasitology, p. 9-19, 2023

• DOI for Transcriptomic analysis of albendazole resistance in human diarrheal parasite Giardia duodenalis
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Trophozoite fitness dictates the intestinal epithelial cell response to Giardia intestinalis infection

Grüttner, Jana; van Rijn, Jorik M.; Geiser, Petra; Florbrant, Alexandra et al.

Part of PLoS Pathogens, 2023

• DOI for Trophozoite fitness dictates the intestinal epithelial cell response to Giardia intestinalis infection
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Ivermectin-induced gene expression changes in adult Parascaris univalens and Caenorhabditis elegans: a comparative approach to study anthelminthic metabolism and resistance in vitro

Dube, Faruk; Hinas, Andrea; Roy, Shweta; Martin, Frida et al.

Part of Parasites & Vectors, 2022

• DOI for Ivermectin-induced gene expression changes in adult Parascaris univalens and Caenorhabditis elegans: a comparative approach to study anthelminthic metabolism and resistance in vitro
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A chromosome-scale reference genome for Spironucleus salmonicida

Xu, Feifei; Jimenez-Gonzalez, Alejandro; Kurt, Zeynep; Ástvaldsson, Ásgeir et al.

Part of Scientific Data, 2022

• DOI for A chromosome-scale reference genome for Spironucleus salmonicida
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Giardia intestinalis thymidine kinase is a high-affinity enzyme crucial for DNA synthesis and an exploitable target for drug discovery

Krakovka, Sascha; Ranjbarian, Farahnaz; Lujan, Lucas A.; Saura, Alicia et al.

Part of Journal of Biological Chemistry, 2022

• DOI for Giardia intestinalis thymidine kinase is a high-affinity enzyme crucial for DNA synthesis and an exploitable target for drug discovery
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Combined nanometric and phylogenetic analysis of unique endocytic compartments in Giardia lamblia sheds light on the evolution of endocytosis in Metamonada

Santos, Rui; Astvaldsson, Asgeir; Pipaliya, Shweta; Zumthor, Jon Paulin et al.

Part of BMC Biology, 2022

• DOI for Combined nanometric and phylogenetic analysis of unique endocytic compartments in Giardia lamblia sheds light on the evolution of endocytosis in Metamonada
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Characterization of Metronidazole-Resistant Giardia intestinalis Lines by Comparative Transcriptomics and Proteomics

Krakovka, Sascha; Ribacke, Ulf; Miyamoto, Yukiko; Eckmann, Lars et al.

Part of Frontiers in Microbiology, 2022

• DOI for Characterization of Metronidazole-Resistant Giardia intestinalis Lines by Comparative Transcriptomics and Proteomics
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High-Definition DIC Imaging Uncovers Transient Stages of Pathogen Infection Cycles on the Surface of Human Adult Stem Cell-Derived Intestinal Epithelium

van Rijn, Jorik M.; Eriksson, Jens; Grüttner, Jana; Sundbom, Magnus et al.

Part of mBio, 2022

• DOI for High-Definition DIC Imaging Uncovers Transient Stages of Pathogen Infection Cycles on the Surface of Human Adult Stem Cell-Derived Intestinal Epithelium
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Comprehensive characterization of Cysteine-rich protein-coding genes of Giardia lamblia and their role during antigenic variation

Rodriguez-Walker, Macarena; Molina, Cecilia R.; Lujan, Lucas A.; Saura, Alicia et al.

Part of Genomics, 2022

• DOI for Comprehensive characterization of Cysteine-rich protein-coding genes of Giardia lamblia and their role during antigenic variation
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Giardia duodenalis

Rojas-Lopez, Laura; Marques, Rafael C.; Svärd, Staffan

Part of Trends in Parasitology, p. 605-606, 2022

• DOI for Giardia duodenalis
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A Detailed Gene Expression Map of Giardia Encystation

Rojas-Lopez, Laura; Krakovka, Sascha; Einarsson, Elin; Ribacke, Ulf et al.

Part of Genes, p. 1932, 2021

• DOI for A Detailed Gene Expression Map of Giardia Encystation
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Serglycin-Deficiency Causes Reduced Weight Gain and Changed Intestinal Cytokine Responses in Mice Infected With Giardia intestinalis

Li, Zhiqiang; Peirasmaki, Dimitra; Svärd, Staffan; Åbrink, Magnus

Part of Frontiers in Immunology, 2021

• DOI for Serglycin-Deficiency Causes Reduced Weight Gain and Changed Intestinal Cytokine Responses in Mice Infected With Giardia intestinalis
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Dual RNA-seq transcriptome analysis of caecal tissue during primary Eimeria tenella infection in chickens

Sandholt, Arnar K. S.; Wattrang, Eva; Lilja, Tobias; Ahola, Harri et al.

Part of BMC Genomics, 2021

• DOI for Dual RNA-seq transcriptome analysis of caecal tissue during primary Eimeria tenella infection in chickens
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Multimodal regulation of encystation in Giardia duodenalis revealed by deep proteomics

Balan, Balu; Emery-Corbin, Samantha J.; Sandow, Jarrod J.; Ansell, Brendan Robert E. et al.

Part of International Journal of Parasitology, p. 809-824, 2021

• DOI for Multimodal regulation of encystation in Giardia duodenalis revealed by deep proteomics
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Eukaryote-conserved histone post-translational modification landscape in Giardia duodenalis revealed by mass spectrometry

Emery-Corbin, Samantha J.; Hamey, Joshua J.; Balan, Balu; Rojas-López, Laura et al.

Part of International Journal of Parasitology, p. 225-239, 2021

• DOI for Eukaryote-conserved histone post-translational modification landscape in Giardia duodenalis revealed by mass spectrometry

Dual RNA-Seq transcriptome analysis of chicken macrophage-like cells (HD11) infected in vitro with Eimeria tenella

Sandholt, Arnar K. S.; Xu, Feifei; Söderlund, Robert; Lundén, Anna et al.

Part of Parasitology, p. 712-725, 2021

• DOI for Dual RNA-Seq transcriptome analysis of chicken macrophage-like cells (HD11) infected in vitro with Eimeria tenella
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Eukaryote-Conserved Methylarginine Is Absent in Diplomonads and Functionally Compensated in Giardia

Emery-Corbin, Samantha J.; Hamey, Joshua J.; Ansell, Brendan R. E.; Balan, Balu et al.

Part of Molecular biology and evolution, p. 3525-3549, 2020

• DOI for Eukaryote-Conserved Methylarginine Is Absent in Diplomonads and Functionally Compensated in Giardia
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High Cysteine Membrane Proteins (HCMPs) Are Up-Regulated DuringGiardia-Host Cell Interactions

Peirasmaki, Dimitra; Ma'ayeh, Showgy Y.; Xu, Feifei; Ferella, Marcela et al.

Part of Frontiers in Genetics, 2020

• DOI for High Cysteine Membrane Proteins (HCMPs) Are Up-Regulated DuringGiardia-Host Cell Interactions
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The Chymase Mouse Mast Cell Protease-4 Regulates Intestinal Cytokine Expression in Mature Adult Mice Infected with Giardia intestinalis

Li, Zhiqiang; Peirasmaki, Dimitra; Svärd, Staffan; Åbrink, Magnus

Part of Cells, 2020

• DOI for The Chymase Mouse Mast Cell Protease-4 Regulates Intestinal Cytokine Expression in Mature Adult Mice Infected with Giardia intestinalis
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The compact genome of Giardia muris reveals important steps in the evolution of intestinal protozoan parasites

Xu, Feifei; Jimenez-Gonzalez, Alejandro; Einarsson, Elin; Ástvaldsson, Ásgeir et al.

Part of Microbial Genomics, 2020

• DOI for The compact genome of Giardia muris reveals important steps in the evolution of intestinal protozoan parasites

A chromosome-scale reference genome for Giardia intestinalis WB

Xu, Feifei; Jex, Aaron; Svärd, Staffan

Part of Scientific Data, 2020

• DOI for A chromosome-scale reference genome for Giardia intestinalis WB
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Giardia intestinalis cystatin is a potent inhibitor of papain, parasite cysteine proteases and, to a lesser extent, human cathepsin B

Liu, Jingyi; Svärd, Staffan; Klotz, Christian

Part of FEBS Letters, p. 1313-1325, 2019

• DOI for Giardia intestinalis cystatin is a potent inhibitor of papain, parasite cysteine proteases and, to a lesser extent, human cathepsin B

Oxygen induces the expression of invasion and stress response genes in the anaerobic salmon parasite Spironucleus salmonicida

Stairs, Courtney W.; Kokla, Anna; Astvaldsson, Asgeir; Jerlström-Hultqvist, Jon et al.

Part of BMC Biology, 2019

• DOI for Oxygen induces the expression of invasion and stress response genes in the anaerobic salmon parasite Spironucleus salmonicida
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Further evaluation of recombinant Tsol-p27 by enzyme-linked immunoelectrotransfer blot for the serodiagnosis of cysticercosis in pigs from Mozambique

Nhancupe, Noemia; Noormahomed, Emilia V.; Afonso, Sonia; Svärd, Staffan et al.

Part of Parasites & Vectors, 2019

• DOI for Further evaluation of recombinant Tsol-p27 by enzyme-linked immunoelectrotransfer blot for the serodiagnosis of cysticercosis in pigs from Mozambique
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Identification of Conserved Candidate Vaccine Antigens in the Surface Proteome of Giardia lamblia

Davids, Barbara J.; Liu, Ching M.; Hanson, Elaine M.; Le, Christine H. Y. et al.

Part of Infection and Immunity, 2019

• DOI for Identification of Conserved Candidate Vaccine Antigens in the Surface Proteome of Giardia lamblia

Proximity Staining using Enzymatic Protein Tagging in Diplomonads

Astvaldsson, Asgeir; Hultenby, Kjell; Svärd, Staffan; Jerlstrom-Hultqvist, Joel

Part of mSphere, 2019

• DOI for Proximity Staining using Enzymatic Protein Tagging in Diplomonads
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Giardia excretory-secretory proteins modulate the enzymatic activities of mast cell chymase and tryptase

Li, Zhiqiang; Peirasmaki, Dimitra; Svärd, Staffan; Åbrink, Magnus

Part of Molecular Immunology, p. 535-544, 2019

• DOI for Giardia excretory-secretory proteins modulate the enzymatic activities of mast cell chymase and tryptase

Cleavage specificity of recombinant Giardia intestinalis cysteine proteases: Degradation of immunoglobulins and defensins

Liu, Jingyi; Fu, Zhirong; Hellman, Lars; Svärd, Staffan G.

Part of Molecular and biochemical parasitology (Print), p. 29-38, 2019

• DOI for Cleavage specificity of recombinant Giardia intestinalis cysteine proteases: Degradation of immunoglobulins and defensins

Proteomic diversity in a prevalent human-infective Giardia duodenalis sub-species

Emery-Corbin, Samantha J.; Vuong, Daniel; Lacey, Ernest; Svärd, Staffan et al.

Part of International Journal of Parasitology, p. 817-823, 2018

• DOI for Proteomic diversity in a prevalent human-infective Giardia duodenalis sub-species

A novel high-resolution multilocus sequence typing of Giardia intestinalis Assemblage A isolates reveals zoonotic transmission, clonal outbreaks and recombination

Ankarklev, Johan; Lebbad, Marianne; Einarsson, Elin; Franzen, Oscar et al.

Part of Infection, Genetics and Evolution, p. 7-16, 2018

• DOI for A novel high-resolution multilocus sequence typing of Giardia intestinalis Assemblage A isolates reveals zoonotic transmission, clonal outbreaks and recombination

Differential protein expression and post-translational modifications in metronidazole-resistant Giardia duodenalis

Emery, Samantha J.; Baker, Louise; Ansell, Brendan R. E.; Mirzaei, Mehdi et al.

Part of GigaScience, 2018

• DOI for Differential protein expression and post-translational modifications in metronidazole-resistant Giardia duodenalis
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Secreted Giardia intestinalis cysteine proteases disrupt intestinal epithelial cell junctional complexes and degrade chemokines

Liu, Jingyi; Ma'ayeh, Showgy Y.; Peirasmaki, Dimitra; Lundstrom-Stadelmann, Britta et al.

Part of Virulence, p. 879-894, 2018

• DOI for Secreted Giardia intestinalis cysteine proteases disrupt intestinal epithelial cell junctional complexes and degrade chemokines
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Responses of the Differentiated Intestinal Epithelial Cell Line Caco-2 to Infection With the Giardia intestinalis GS Isolate

Ma'ayeh, Showgy Y.; Knörr, Livia; Sköld, Karin; Garnham, Alexandra et al.

Part of Frontiers in Cellular and Infection Microbiology, 2018

• DOI for Responses of the Differentiated Intestinal Epithelial Cell Line Caco-2 to Infection With the Giardia intestinalis GS Isolate
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Recent advances in the genomic and molecular biology of Giardia

Guadalupe Ortega-Pierres, M.; Jex, Aaron R.; Ansell, Brendan R. E.; Svärd, Staffan

Part of Acta Tropica, p. 67-72, 2018

• DOI for Recent advances in the genomic and molecular biology of Giardia

Transcriptomics Indicates Active and Passive Metronidazole Resistance Mechanisms in Three Seminal Giardia Lines

Ansell, Brendan R. E.; Baker, Louise; Emery, Samantha J.; McConville, Malcolm J. et al.

Part of Frontiers in Microbiology, 2017

• DOI for Transcriptomics Indicates Active and Passive Metronidazole Resistance Mechanisms in Three Seminal Giardia Lines
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Giardia intestinalis mitosomes undergo synchronized fission but not fusion and are constitutively associated with the endoplasmic reticulum

Voleman, Lubos; Najdrova, Vladimira; Ástvaldsson, Ásgeir; Tumova, Pavla et al.

Part of BMC Biology, 2017

• DOI for Giardia intestinalis mitosomes undergo synchronized fission but not fusion and are constitutively associated with the endoplasmic reticulum
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Giardia-specific cellular immune responses in post-giardiasis chronic fatigue syndrome

Hanevik, Kurt; Kristoffersen, Einar; Morch, Kristine; Rye, Kristin Paulsen et al.

Part of BMC Immunology, 2017

• DOI for Giardia-specific cellular immune responses in post-giardiasis chronic fatigue syndrome
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Characterization of the Giardia intestinalis secretome during interaction with human intestinal epithelial cells: The impact on host cells

Ma'ayeh, Showgy Y.; Liu, Jingyi; Peirasmaki, Dimitra; Hörnaeus, Katarina et al.

Part of PLoS Neglected Tropical Diseases, 2017

• DOI for Characterization of the Giardia intestinalis secretome during interaction with human intestinal epithelial cells: The impact on host cells
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Endoplasmic reticulum is the sorting core facility in the Golgi-lacking protozoan Giardia lamblia

Zamponi, Nahuel; Zamponi, Emiliano; Mayol, Gonzalo F.; Lanfredi-Rangel, Adriana et al.

Part of Traffic, p. 604-621, 2017

• DOI for Endoplasmic reticulum is the sorting core facility in the Golgi-lacking protozoan Giardia lamblia

On the reversibility of parasitism: adaptation to a free-living lifestyle via gene acquisitions in the diplomonad Trepomonas sp PC1

Xu, Feifei; Jerlström-Hultqvist, Jon; Kolisko, Martin; Simpson, Alastair G. B. et al.

Part of BMC Biology, 2016

• DOI for On the reversibility of parasitism: adaptation to a free-living lifestyle via gene acquisitions in the diplomonad Trepomonas sp PC1
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Comparative cell biology and evolution of Annexins in Diplomonads

Einarsson, Elin; Ástvaldsson, Ásgeir; Hultenby, Kjell; Andersson, Jan O. et al.

Part of mSphere, 2016

• DOI for Comparative cell biology and evolution of Annexins in Diplomonads

Divergent Transcriptional Responses to Physiological and Xenobiotic Stress in Giardia duodenalis

Ansell, Brendan R. E.; McConville, Malcolm J.; Baker, Louise; Korhonen, Pasi K. et al.

Part of Antimicrobial Agents and Chemotherapy, p. 6034-6045, 2016

• DOI for Divergent Transcriptional Responses to Physiological and Xenobiotic Stress in Giardia duodenalis

Coordinated Changes in Gene Expression Throughout Encystation of Giardia intestinalis

Einarsson, Elin; Troell, Karin; Höppner, Marc; Grabherr, Mannfred et al.

Part of PLoS Neglected Tropical Diseases, 2016

• DOI for Coordinated Changes in Gene Expression Throughout Encystation of Giardia intestinalis
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Specific histone modifications play critical roles in the control of encystation and antigenic variation in the early-branching eukaryote Giardia lamblia

Carranza, Pedro G.; Gargantini, Pablo R.; Prucca, Cesar G.; Torri, Alessandro et al.

Part of International Journal of Biochemistry and Cell Biology, p. 32-43, 2016

• DOI for Specific histone modifications play critical roles in the control of encystation and antigenic variation in the early-branching eukaryote Giardia lamblia

Human Memory CD4+ T Cell Immune Responses against Giardia lamblia

Saghaug, Christina Skar; Sornes, Steinar; Peirasmaki, Dimitra; Svärd, Staffan et al.

Part of Clinical and Vaccine Immunology, p. 11-18, 2016

• DOI for Human Memory CD4+ T Cell Immune Responses against Giardia lamblia

Comparative genomic analyses of freshly isolated Giardia intestinalis assemblage A isolates

Ankarklev, Johan; Franzen, Oscar; Peirasmaki, Dimitra; Jerlstrom-Hultqvist, Jon et al.

Part of BMC Genomics, 2015

• DOI for Comparative genomic analyses of freshly isolated Giardia intestinalis assemblage A isolates
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UV irradiation responses in Giardia intestinalis

Einarsson, Elin; Svärd, Staffan G.; Troell, Karin

Part of Experimental parasitology, p. 25-32, 2015

• DOI for UV irradiation responses in Giardia intestinalis

A real-time assemblage-specific PCR assay for the detection of Giardia duodenalis assemblages A, B and E in fecal samples

Van Lith, Lindy; Soba, Barbara; Vizcaino, Vivian Villalba; Svärd, Staffan et al.

Part of Veterinary parasitology, p. 28-34, 2015

• DOI for A real-time assemblage-specific PCR assay for the detection of Giardia duodenalis assemblages A, B and E in fecal samples

Transcriptional profiling of Giardia intestinalis in response to oxidative stress

Ma'ayeh, Showgy Y.; Knörr, Livia; Svärd, Staffan G.

Part of International Journal of Parasitology, p. 925-938, 2015

• DOI for Transcriptional profiling of Giardia intestinalis in response to oxidative stress

Time-Dependent Transcriptional Changes in Axenic Giardia duodenalis Trophozoites

Ansell, Brendan R. E.; McConville, Malcolm J.; Baker, Louise; Korhonen, Pasi K. et al.

Part of PLoS Neglected Tropical Diseases, 2015

• DOI for Time-Dependent Transcriptional Changes in Axenic Giardia duodenalis Trophozoites
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The genome of Spironucleus salmonicida highlights a fish pathogen adapted to fluctuating environments

Xu, Feifei; Jerlström-Hultqvist, Jon; Einarsson, Elin; Astvaldsson, Asgeir et al.

Part of PLOS Genetics, 2014

• DOI for The genome of Spironucleus salmonicida highlights a fish pathogen adapted to fluctuating environments
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Rolf Bernander (1956-2014): pioneer of the archaeal cell cycle Obituary

Ettema, Thijs J. G.; Lindås, Ann-Christin; Hjort, Karin; Poplawski, Andrzej B. et al.

Part of Molecular Microbiology, p. 903-909, 2014

• DOI for Rolf Bernander (1956-2014): pioneer of the archaeal cell cycle Obituary

Gene expression changes during Giardia-host cell interactions in serum-free medium

Ferella, Marcela; Davids, Barbara J; Cipriano, Michael J; Birkeland, Shanda R et al.

Part of Molecular and biochemical parasitology (Print), p. 21-23, 2014

• DOI for Gene expression changes during Giardia-host cell interactions in serum-free medium

The role of arginine and arginine-metabolizing enzymes during Giardia - host cell interactions in vitro

Stadelmann, Britta; Hanevik, Kurt; Andersson, Mattias K.; Bruserud, Oystein et al.

Part of BMC Microbiology, p. 256, 2013

• DOI for The role of arginine and arginine-metabolizing enzymes during Giardia - host cell interactions in vitro

Transcriptome Profiling of Giardia intestinalis Using Strand-specific RNAseq

Franzén, Oscar; Jerlström-Hultqvist, Jon; Einarsson, Elin; Ankarklev, Johan et al.

Part of PloS Computational Biology, 2013

• DOI for Transcriptome Profiling of Giardia intestinalis Using Strand-specific RNAseq
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Hydrogenosomes in the diplomonad Spironucleus salmonicida

Jerlström-Hultqvist, Jon; Einarsson, Elin; Xu, Feifei; Hjort, Karin et al.

Part of Nature Communications, p. 2493, 2013

• DOI for Hydrogenosomes in the diplomonad Spironucleus salmonicida

Common Coinfections of Giardia intestinalis and Helicobacter pylori in Non-Symptomatic Ugandan Children

Ankarklev, Johan; Hestvik, Elin; Lebbad, Marianne; Lindh, Johan et al.

Part of PLOS Neglected Tropical Diseases, 2012

• DOI for Common Coinfections of Giardia intestinalis and Helicobacter pylori in Non-Symptomatic Ugandan Children
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Allelic sequence heterozygosity in single Giardia parasites

Ankarklev, Johan; Svärd, Staffan; Lebbad, Marianne

Part of BMC Microbiology, 2012

• DOI for Allelic sequence heterozygosity in single Giardia parasites

Plasmid Vectors for Proteomic Analyses in Giardia: Purification of Virulence Factors and Analysis of the Proteasome

Jerlström-Hultqvist, Jon; Stadelmann, Britta; Birkestedt, Sandra; Hellman, Ulf et al.

Part of Eukaryotic Cell, p. 864-873, 2012

• DOI for Plasmid Vectors for Proteomic Analyses in Giardia: Purification of Virulence Factors and Analysis of the Proteasome

Arginine Consumption by the Intestinal Parasite Giardia intestinalis Reduces Proliferation of Intestinal Epithelial Cells

Stadelmann, Britta; Merino, Maria C.; Persson, Lo; Svärd, Staffan G.

Part of PLOS ONE, 2012

• DOI for Arginine Consumption by the Intestinal Parasite Giardia intestinalis Reduces Proliferation of Intestinal Epithelial Cells
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Laboratory cryo soft X-ray microscopy

Hertz, H. M.; von Hofsten, O.; Bertilson, M.; Vogt, U. et al.

Part of Journal of Structural Biology, p. 267-272, 2012

• DOI for Laboratory cryo soft X-ray microscopy

Alpha-1 Giardin is an Annexin with Highly Unusual Calcium-Regulated Mechanisms

Weeratunga, Saroja K.; Osman, Asiah; Hu, Nien-Jen; Wang, Conan K. et al.

Part of Journal of Molecular Biology, p. 169-181, 2012

• DOI for Alpha-1 Giardin is an Annexin with Highly Unusual Calcium-Regulated Mechanisms

Stable transfection of the diplomonad parasite Spironucleus salmonicida

Jerlström-Hultqvist, Jon; Einarsson, Elin; Svärd, Staffan G

Part of Eukaryotic Cell, p. 1353-1361, 2012

• DOI for Stable transfection of the diplomonad parasite Spironucleus salmonicida

Detection of Giardia duodenalis Assemblages A and B in Human Feces by Simple, Assemblage-Specific PCR Assays

Vanni, Ilaria; Caccio, Simone Mario; van Lith, Lindy; Lebbad, Marianne et al.

Part of PLOS Neglected Tropical Diseases, 2012

• DOI for Detection of Giardia duodenalis Assemblages A and B in Human Feces by Simple, Assemblage-Specific PCR Assays
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Transcriptional changes in Giardia during host-parasite interactions

Ringqvist, Emma; Avesson, Lotta; Söderbom, Fredrik; Svärd, Staffan

Part of International Journal for Parasitology, p. 277-285, 2011

• DOI for Transcriptional changes in Giardia during host-parasite interactions

Real-time polymerase chain reaction followed by fast sequencing allows rapid genotyping of microbial pathogens

Wahab, Tara; Ankarklev, Johan; Lebbad, Marianne; Glavas, Steve et al.

Part of Scandinavian Journal of Infectious Diseases, p. 95-99, 2011

• DOI for Real-time polymerase chain reaction followed by fast sequencing allows rapid genotyping of microbial pathogens

Multilocus Genotyping of Human Giardia Isolates Suggests Limited Zoonotic Transmission and Association between Assemblage B and Flatulence in Children

Lebbad, Marianne; Petersson, Ingvor; Karlsson, Lillemor; Botero-Kleiven, Silvia et al.

Part of PLoS Neglected Tropical Diseases, 2011

• DOI for Multilocus Genotyping of Human Giardia Isolates Suggests Limited Zoonotic Transmission and Association between Assemblage B and Flatulence in Children

Elongation factor 1-alpha is released into the culture medium during growth of Giardia intestinalis trophozoites

Skarin, Hanna; Ringqvist, Emma; Hellman, Ulf; Svärd, Staffan G.

Part of Experimental parasitology, p. 804-810, 2011

• DOI for Elongation factor 1-alpha is released into the culture medium during growth of Giardia intestinalis trophozoites

The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology

Manning, Gerard; Reiner, David S.; Lauwaet, Tineke; Dacre, Michael et al.

Part of Genome Biology, 2011

• DOI for The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology
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Human Cellular Immune Response Against Giardia lamblia 5 Years After Acute Giardiasis

Hanevik, Kurt; Kristoffersen, Einar; Svärd, Staffan; Bruserud, Oystein et al.

Part of Journal of Infectious Diseases, p. 1779-1786, 2011

• DOI for Human Cellular Immune Response Against Giardia lamblia 5 Years After Acute Giardiasis

alpha 1-giardin based live heterologous vaccine protects against Giardia lamblia infection in a murine model

Jenikova, Gabriela; Hruz, Petr; Andersson, Mattias K.; Tejman-Yarden, Noa et al.

Part of Vaccine, p. 9529-9537, 2011

• DOI for alpha 1-giardin based live heterologous vaccine protects against Giardia lamblia infection in a murine model

Large genomic differences between the morphologically indistinguishable diplomonads Spironucleus barkhanus and Spironucleus salmonicida

Roxström-Lindquist, Katarina; Jerlström-Hultqvist, Jon; Jörgensen, Anders; Troell, Karin et al.

Part of BMC Genomics, 2010

• DOI for Large genomic differences between the morphologically indistinguishable diplomonads Spironucleus barkhanus and Spironucleus salmonicida
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Comment on article by Eligio-Garcia et al. entitled "Frequency of Giardia intestinalis assemblages isolated from dogs and humans in a community from Culiacan, Sinaloa, Mexico using beta-giardin restriction gene"

Lebbad, Marianne; Svärd, Staffan

Part of Veterinary parasitology, p. 159-160, 2008

• DOI for Comment on article by Eligio-Garcia et al. entitled "Frequency of Giardia intestinalis assemblages isolated from dogs and humans in a community from Culiacan, Sinaloa, Mexico using beta-giardin restriction gene"

Dominance of Giardia assemblage B in León, Nicaragua.

Lebbad, Marianne; Ankarklev, Johan; Tellez, Aleyda; Leiva, Byron et al.

Part of Acta Tropica, p. 44-53, 2008

• DOI for Dominance of Giardia assemblage B in León, Nicaragua.

Eukaryotic RNase P RNA mediates cleavage in the absence of protein

Kikovska, Ema; Svärd, Staffan; Kirsebom, Leif

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 2062-2067, 2007

• DOI for Eukaryotic RNase P RNA mediates cleavage in the absence of protein

Protein phosphatase 2A plays a crucial role in Giardia lamblia differentiation

Lauwaet, Tineke; Davids, Barbara J.; Torres-Escobar, Ascención; Birkeland, Shanda R. et al.

Part of Molecular and biochemical parasitology (Print), p. 80-89, 2007

• DOI for Protein phosphatase 2A plays a crucial role in Giardia lamblia differentiation

Giardia lamblia-induced changes in gene expression in differentiated Caco-2

Roxström-Lindquist, Katarina; Ringqvist, Emma; Palm, Daniel; Svärd, Staffan

Part of Infect Immun, p. 8204-8, 2005

Secretory antibodies against Giardia intestinalis in lactating Nicaraguan women.

Tellez, A; Palm, D; Weiland, M; Alemán, J et al.

Part of Parasite Immunol, p. 163-9, 2005

Developmental changes in the adhesive disk during Giardia differentiation.

Palm, Daniel; Weiland, Malin; McArthur, Andrew G; Winiecka-Krusnell, Jadwiga et al.

Part of Mol Biochem Parasitol, p. 199-207, 2005

Update on Giardia: Highlights from the seventh International Giardia and Cryptosporidium Conference

Buret, Andre G.; Caccio, Simone M.; Favennec, Loic; Svärd, Staffan

Part of Parasite, 2020

• DOI for Update on Giardia: Highlights from the seventh International Giardia and Cryptosporidium Conference
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Host specificity in the Giardia duodenalis species complex

Caccio, Simone M.; Lalle, Marco; Svärd, Staffan

Part of Infection, Genetics and Evolution, p. 335-345, 2018

• DOI for Host specificity in the Giardia duodenalis species complex

An up-date on Giardia and giardiasis

Einarsson, Elin; Ma'ayeh, Showgy Y.; Svärd, Staffan G.

Part of Current Opinion in Microbiology, p. 47-52, 2016

• DOI for An up-date on Giardia and giardiasis

Drug resistance in Giardia duodenalis

Ansell, Brendan R. E.; McConville, Malcolm J.; Ma'ayeh, Showgy Y.; Dagley, Michael J. et al.

Part of Biotechnology Advances, p. 888-901, 2015

• DOI for Drug resistance in Giardia duodenalis

Behind the smile: cell biology and disease mechanisms of Giardia species

Ankarklev, Johan; Jerlström-Hultqvist, Jon; Ringqvist, Emma; Troell, Karin et al.

Part of Nature Reviews Microbiology, p. 413-422, 2010

• DOI for Behind the smile: cell biology and disease mechanisms of Giardia species

A genomic survey of the fish parasite Spironucleus salmonicida indicates genomic plasticity among diplomonads and significant lateral gene transfer in eukaryote genome evolution

Andersson, Jan O.; Sjögren, Åsa M.; Horner, David S.; Murphy, Colleen A. et al.

Part of BMC Genomics, p. 51, 2007

• DOI for A genomic survey of the fish parasite Spironucleus salmonicida indicates genomic plasticity among diplomonads and significant lateral gene transfer in eukaryote genome evolution

Giardia and giardiasis

Ma'ayeh, Showgy Y.; Svärd, Staffan

Part of Molecular Medical Microbiology, p. 3107-3119, Elsevier, 2023

• DOI for Giardia and giardiasis

Transcriptomic and proteomic analyses of Giardia intestinalis: Intestinal epithelial cell interactions

Emery-Corbin, Samantha J.; Grüttner, Jana; Svärd, Staffan

Part of Giardia And Giardiasis, Pt B, p. 139-171, Elsevier, 2020

• DOI for Transcriptomic and proteomic analyses of Giardia intestinalis: Intestinal epithelial cell interactions

Recent advances in functional research in Giardia intestinalis

Jex, Aaron R.; Svärd, Staffan; Hagen, Kari D.; Starcevich, Hannah et al.

Part of Giardia And Giardiasis, Pt B, p. 97-137, Elsevier, 2020

• DOI for Recent advances in functional research in Giardia intestinalis

The genome of Giardia and other diplomonads

Andersson, Jan O.; Jerlström-Hultqvist, Jon; Svärd, Staffan G.

Part of Anaerobic Parasitic Protozoa: Genomics and Molecular Biology, p. 23-44, Caister Academic Press, 2010

Occurrence of intestinal parasites and bacteria, with the emphasis on Giardia intestinalis in children under 5 years old in Magude village, Maputo, Mozambique

Casmo, Veronica; Noormahomed, Emilia; Knörr, Livia; Lebbad, Marianne et al.

2024

Experimental challenge of Atlantic salmon (Salmo salar) with the diplomonad parasite Spironucleus salmonicida to characterize the infection cycle

Anders, Alfjorden; Astvaldsson, Asgeir; Eva, Jansson; Svärd, Staffan

High Cysteine Proteins are up-regulated during Giardia-host cell interaction.

Peirasmaki, Dimitra; Ma'ayeh, Showgy Y.; Xu, Feifei; Ferella, Marcela et al.

Proteome analyses of Giardia–host cell interactions in vitro.

Peirasmaki, Dimitra; Xia, Dong; Attree, Elizabeth; Ferella, Marcela et al.

Proteomic profiling of host cell responses during Giardia intestinalis interaction with intestinal epithelial Caco-2 cells

Grüttner, Jana; Svärd, Staffan

Dual transcriptomic analysis of Spironucleus salmonicida-infected salmon cells identifies putative virulence factors and host responses

Astvaldsson, Asgeir; Stairs, Courtney W.; Xu, Feifei; Haag, Lars et al.