Publications

Ossification of the pectoral fin of Glyptolepis groenlandica: implications for the evolution of the lungfish appendicular skeleton

Branigan, M. K.; Bijl, S.; Ahlberg, P. E.; Tafforeau, P. et al.

Part of Developmental Biology Advances, 2026

Article in journal

• DOI for Ossification of the pectoral fin of Glyptolepis groenlandica: implications for the evolution of the lungfish appendicular skeleton

Investigating the Morphogenesis and Replacement of Lamprey Toothlets Using Synchrotron Imaging

Grohganz, Madleen; Leyhr, Jake; Johanson, Zerina; Haitina, Tatjana et al.

Part of Journal of morphology, 2025

Article, review/survey

• DOI for Investigating the Morphogenesis and Replacement of Lamprey Toothlets Using Synchrotron Imaging
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Acquisition of neural crest promoted thyroid evolution from chordate endostyle

Stundl, Jan; Rajan, Ayyappa Raja Desingu; Urrutia, Hugo A.; Leyhr, Jake et al.

Part of Science Advances, 2025

Article in journal

• DOI for Acquisition of neural crest promoted thyroid evolution from chordate endostyle
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Nkx2.7 is a conserved regulator of craniofacial development

Ford, Caitlin; de Sena-Tomas, Carmen; Wun, Tint Tha Ra; Aleman, Angelika G. et al.

Part of Nature Communications, 2025

Article in journal

• DOI for Nkx2.7 is a conserved regulator of craniofacial development
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The overlooked first intercostal ligament: Does it help to stabilize the Weberian apparatus?

Leyhr, Jake; Haitina, Tatjana; Bird, Nathan C.

Part of Journal of Anatomy, p. 288-298, 2025

Article in journal

• DOI for The overlooked first intercostal ligament: Does it help to stabilize the Weberian apparatus?
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The Sensory Shark: High-quality Morphological, Genomic and Transcriptomic Data for the Small-spotted Catshark Scyliorhinus Canicula Reveal the Molecular Bases of Sensory Organ Evolution in Jawed Vertebrates

Mayeur, Hélène; Leyhr, Jake; Mulley, John; Leurs, Nicolas et al.

Part of Molecular biology and evolution, 2024

Article in journal

• DOI for The Sensory Shark: High-quality Morphological, Genomic and Transcriptomic Data for the Small-spotted Catshark Scyliorhinus Canicula Reveal the Molecular Bases of Sensory Organ Evolution in Jawed Vertebrates
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Multiple cis-regulatory elements control prox1a expression in distinct lymphatic vascular beds

Panara, Virginia; Yu, Hujun; Peng, Di; Staxäng, Karin et al.

Part of Development, 2024

Article in journal

• DOI for Multiple cis-regulatory elements control prox1a expression in distinct lymphatic vascular beds

Evolutionary Genomics of Odontode Tissues

Haitina, Tatjana; Debiais-Thibaud, Melanie

Part of Odontodes, p. 41, CRC Press, 2023

Chapter in book

• DOI for Evolutionary Genomics of Odontode Tissues

Ancient vertebrate dermal armor evolved from trunk neural crest

Stundl, Jan; Martik, Megan L.; Chen, Donglei; Raja, Desingu Ayyappa et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, 2023

Article in journal

• DOI for Ancient vertebrate dermal armor evolved from trunk neural crest

Enhanced contrast synchrotron X-ray microtomography for describing skeleton-associated soft tissue defects in zebrafish mutants

Leyhr, Jake; Sanchez, Sophie; Dollman, Kathleen N.; Tafforeau, Paul et al.

Part of Frontiers in Endocrinology, 2023

Article in journal

• DOI for Enhanced contrast synchrotron X-ray microtomography for describing skeleton-associated soft tissue defects in zebrafish mutants
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A novel cis-regulatory element drives early expression of Nkx3.2 in the gnathostome primary jaw joint

Leyhr, Jake; Waldmann, Laura; Filipek-Górniok, Beata; Zhang, Hanqing et al.

Part of eLIFE, 2022

Article in journal

• DOI for A novel cis-regulatory element drives early expression of Nkx3.2 in the gnathostome primary jaw joint
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The Role of Gdf5 in the Development of the Zebrafish Fin Endoskeleton

Waldmann, Laura; Leyhr, Jake; Zhang, Hanqing; Allalou, Amin et al.

Part of Developmental Dynamics, p. 1535-1549, 2022

Article in journal

• DOI for The Role of Gdf5 in the Development of the Zebrafish Fin Endoskeleton
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The broad role of Nkx3.2 in the development of the zebrafish axial skeleton

Waldmann, Laura; Leyhr, Jake; Zhang, Hanqing; Öhman, Caroline et al.

Part of PLOS ONE, 2021

Article in journal

• DOI for The broad role of Nkx3.2 in the development of the zebrafish axial skeleton
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Evolution of Matrix Gla and Bone Gla Protein Genes in Jawed Vertebrates

Leurs, Nicolas; Martinand-Mari, Camille; Venteo, Stephanie; Haitina, Tatjana et al.

Part of Frontiers in Genetics, 2021

Article in journal

• DOI for Evolution of Matrix Gla and Bone Gla Protein Genes in Jawed Vertebrates
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Chapter 8 Neural Crest in Fossil Vertebrates: What, If Anything, Can We Know?

Ahlberg, Per; Haitina, Tatjana

Part of Evolving Neural Crest Cells, p. 1-294, Taylor & Francis Group, 2020

Chapter in book

• DOI for Chapter 8 Neural Crest in Fossil Vertebrates: What, If Anything, Can We Know?

Reconstruction of the Carbohydrate 6-O Sulfotransferase Gene Family Evolution in Vertebrates Reveals Novel Member, CHST16, Lost in Amniotes

Ocampo Daza, Daniel; Haitina, Tatjana

Part of Genome Biology and Evolution, p. 993-1012, 2020

Article in journal

• DOI for Reconstruction of the Carbohydrate 6-O Sulfotransferase Gene Family Evolution in Vertebrates Reveals Novel Member, CHST16, Lost in Amniotes
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zOPT: an open source optical projection tomography system and methods for rapid 3D zebrafish imaging

Zhang, Hanqing; Waldmann, Laura; Manuel, Remy; Boije, Henrik et al.

Part of Biomedical Optics Express, p. 4290-4305, 2020

Article in journal

• DOI for zOPT: an open source optical projection tomography system and methods for rapid 3D zebrafish imaging
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Skeletal Mineralization in Association with Type X Collagen Expression Is an Ancestral Feature for Jawed Vertebrates

Debiais-Thibaud, Melanie; Simion, Paul; Venteo, Stephanie; Munoz, David et al.

Part of Molecular biology and evolution, p. 2265-2276, 2019

Article in journal

• DOI for Skeletal Mineralization in Association with Type X Collagen Expression Is an Ancestral Feature for Jawed Vertebrates
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Utvecklingsbiologi-: komplexa processer när en ny individ blir till

Haitina, Tatjana

Part of Fascinerande forskning, p. 38-42, Nationellt resurscentrum för biologi och bioteknik, 2018

Chapter in book

Molecular mechanism of articular cartilage establishment during the evolution of vertebrates

Haitina, Tatjana

p. 42, 2017

Conference paper

Characterization of synovial joint progenitor cells in zebrafish

Waldmann, Laura; Haitina, Tatjana

Part of Characterization of synovial joint progenitor cells in zebrafish, p. 26, 2017

Conference paper

Vascularization and odontode structure of a dorsal ridge spine of Romundina stellina Ørvig 1975

Jerve, Anna; Qu, Qinming; Sanchez, Sophie; Ahlberg, Per Erik et al.

Part of PLOS ONE, 2017

Article in journal

• DOI for Vascularization and odontode structure of a dorsal ridge spine of Romundina stellina Ørvig 1975
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The role of transcription factors during the development of craniofacial tendons and ligaments

Haitina, Tatjana

p. 22, 2016

Conference paper

Nematodes join the family of chondroitin sulfate-synthesizing organisms: Identification of an active chondroitin sulfotransferase in Caenorhabditis elegans

Dierker, Tabea; Shao, Chun; Haitina, Tatjana; Zaia, Joseph et al.

Part of Scientific Reports, 2016

Article in journal

• DOI for Nematodes join the family of chondroitin sulfate-synthesizing organisms: Identification of an active chondroitin sulfotransferase in Caenorhabditis elegans
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mRNA GPR162 changes are associated with decreased food intake in rat, and its human genetic variants with impairments in glucose homeostasis in two Swedish cohorts

Caruso, Vanni; Sreedharan, Smitha; Carlini, Valeria P.; Jacobsson, Josefin A. et al.

Part of Gene, p. 139-145, 2016

Article in journal

• DOI for mRNA GPR162 changes are associated with decreased food intake in rat, and its human genetic variants with impairments in glucose homeostasis in two Swedish cohorts

Divergent expression patterns of teleost specific gene duplicates during the development of craniofacial tendons and ligaments

Onsbring Gustafson, Henning; Haitina, Tatjana

2015

Conference paper

Identification of enamel matrix protein genes in the genome of spotted gar Lepisosteus oculatus

Haitina, Tatjana; Qu, Qinming; Ahlberg, Per

p. 40, 2015

Conference paper

The Orphan G Protein-Coupled Receptor Gene GPR178 Is Evolutionary Conserved and Altered in Response to Acute Changes in Food Intake

Caruso, Vanni; Le Greves, Madeleine; Fard, Shahrzad Shirazi; Haitina, Tatjana et al.

Part of PLOS ONE, 2015

Article in journal

• DOI for The Orphan G Protein-Coupled Receptor Gene GPR178 Is Evolutionary Conserved and Altered in Response to Acute Changes in Food Intake
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Chondroitin / Dermatan Sulfate Modification Enzymes in Zebrafish Development

Habicher, Judith; Haitina, Tatjana; Eriksson, Inger; Holmborn, Katarina et al.

Part of PLOS ONE, 2015

Article in journal

• DOI for Chondroitin / Dermatan Sulfate Modification Enzymes in Zebrafish Development
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The Ndst Gene Family in Zebrafish: Role of Ndst1b in Pharyngeal Arch Formation

Filipek-Gorniok, Beata; Carlsson, Pernilla; Haitina, Tatjana; Habicher, Judith et al.

Part of PLOS ONE, 2015

Article in journal

• DOI for The Ndst Gene Family in Zebrafish: Role of Ndst1b in Pharyngeal Arch Formation
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New genomic and fossil data illuminate the origin of enamel

Qu, Qingming; Haitina, Tatjana; Zhu, Min; Ahlberg, Per Erik

Part of Nature, p. 108-120, 2015

Article in journal

• DOI for New genomic and fossil data illuminate the origin of enamel

The genome of Callorhinchus and the fossil record: a new perspective on SCPP gene evolution in gnathostomes

Ryll, Bettina; Sanchez, Sophie; Haitina, Tatjana; Tafforeau, Paul et al.

Part of Evolution & Development, p. 123-124, 2014

Article in journal

• DOI for The genome of Callorhinchus and the fossil record: a new perspective on SCPP gene evolution in gnathostomes

Expression of chondroitin/dermatan sulfate glycosyltransferases during early zebrafish development

Filipek-Gorniok, Beata; Holmborn, Katarina; Haitina, Tatjana; Habicher, Judith et al.

Part of Developmental Dynamics, p. 964-975, 2013

Article in journal

• DOI for Expression of chondroitin/dermatan sulfate glycosyltransferases during early zebrafish development

Regulation of genes involved in the development of the pharyngeal arches

Haitina, Tatjana

Part of Regulation of genes involved in the development of the pharyngeal arches, 2011

Conference paper

The G protein coupled receptor Gpr153 shares common evolutionary origin with Gpr162 and is highly expressed in central regions including the thalamus, cerebellum and the arcuate nucleus

Sreedharan, Smitha; Sällman Almén, Markus; Carlini, Valeria P; Haitina, Tatjana et al.

Part of The FEBS Journal, p. 4881-4894, 2011

Article in journal

• DOI for The G protein coupled receptor Gpr153 shares common evolutionary origin with Gpr162 and is highly expressed in central regions including the thalamus, cerebellum and the arcuate nucleus

GPR162 is expressed in the hypothalamus and is involved in food intake related behaviour

Sreedharan, Smitha; Carlini, Valeria P; Jacobsson, Josefin A; Olszewski, Pawel K et al.

2011

Manuscript (preprint)

The G protein-coupled receptor subset of the dog genome is more similar to that in humans than rodents

Haitina, Tatjana; Fredriksson, Robert; Foord, Steven M.; Schiöth, Helgi B. et al.

Part of BMC Genomics, p. 24, 2009

Article in journal

• DOI for The G protein-coupled receptor subset of the dog genome is more similar to that in humans than rodents

Function, Pharmacology, Evolution and Anatomical Localization of G Protein-Coupled Receptors and Solute Carriers

Haitina, Tatjana

2009

Doctoral thesis, comprehensive summary

• Download full text (pdf) of Function, Pharmacology, Evolution and Anatomical Localization of G Protein-Coupled Receptors and Solute Carriers

Expression profile of the entire family of Adhesion G protein-coupled receptors in mouse and rat

Haitina, Tatjana; Olsson, Fredrik; Stephansson, Olga; Alsiö, Johan et al.

Part of BMC Neuroscience, p. 43, 2008

Article in journal

• DOI for Expression profile of the entire family of Adhesion G protein-coupled receptors in mouse and rat

Identification of six putative human transporters with structural similarity to the drug transporter SLC22 family

Jacobsson, Josefin A.; Haitina, Tatjana; Lindblom, Jonas; Fredriksson, Robert

Part of Genomics, p. 595-609, 2007

Article in journal

• DOI for Identification of six putative human transporters with structural similarity to the drug transporter SLC22 family

The evolutionary history and tissue mapping of GPR123: specific CNS expression pattern predominantly in thalamic nuclei and regions containing large pyramidal cells

Lagerström, Malin C.; Rabe, Nadine; Haitina, Tatjana; Kalnina, Ineta et al.

Part of Journal of Neurochemistry, p. 1129-1142, 2007

Article in journal

• DOI for The evolutionary history and tissue mapping of GPR123: specific CNS expression pattern predominantly in thalamic nuclei and regions containing large pyramidal cells

Functional characterization of two melanocortin (MC) receptors in lamprey showing orthology to the MC1 and MC4 receptor subtypes

Haitina, Tatjana; Klovins, Janis; Takahashi, Akiyoshi; Löwgren, Maja et al.

Part of BMC Evolutionary Biology, p. 101, 2007

Article in journal

• DOI for Functional characterization of two melanocortin (MC) receptors in lamprey showing orthology to the MC1 and MC4 receptor subtypes

High diversity in functional properties of melanocortin 1 receptor (MC1R) in divergent primate species is more strongly associated with phylogeny than coat color

Haitina, Tatjana; Ringholm, Aneta; Kelly, Joanne; Mundy, Nicholas I et al.

Part of Molecular biology and evolution, p. 2001-2008, 2007

Article in journal

• DOI for High diversity in functional properties of melanocortin 1 receptor (MC1R) in divergent primate species is more strongly associated with phylogeny than coat color

Further evidence for ancient role of ACTH peptides at melanocortin (MC) receptors; pharmacology of dogfish and lamprey peptides at dogfish MC receptors

Haitina, Tatjana; Takahashi, Akiyoshi; Holmén, Linnea; Enberg, Johan et al.

Part of Peptides, p. 798-805, 2007

Article in journal

• DOI for Further evidence for ancient role of ACTH peptides at melanocortin (MC) receptors; pharmacology of dogfish and lamprey peptides at dogfish MC receptors

Fourteen novel human members of mitochondrial solute carrier family 25 (SLC25) widely expressed in the central nervous system

Haitina, Tatjana; Lindblom, Jonas; Renström, Thomas; Fredriksson, Robert

Part of Genomics, p. 779-790, 2006

Article in journal

• DOI for Fourteen novel human members of mitochondrial solute carrier family 25 (SLC25) widely expressed in the central nervous system

Gene structure of the goldfish agouti-signaling protein: a putative role in the dorsla-ventral pigment pattern of fish

Cerda-Reverter, JM; Haitina, T; Schiöth, HB; Peter, RE

Part of Endocrinology, p. 1597-610, 2005

Article in journal

• DOI for Gene structure of the goldfish agouti-signaling protein: a putative role in the dorsla-ventral pigment pattern of fish

Differential regulation of nuclear receptors, neuropeptides and peptide hormones in the hypothalamus and pituitary of food restricted rats

Lindblom, Jonas; Haitina, Tatjana; Fredriksson, Robert; Schiöth, Helgi B

Part of Brain Research, p. 37-46, 2005

Article in journal

• DOI for Differential regulation of nuclear receptors, neuropeptides and peptide hormones in the hypothalamus and pituitary of food restricted rats

Unusual genomic structure: melanocortin receptors in fugu

Schiöth, Helgi B.; Haitina, Tatjana; Fridmanis, Davids; Klovins, Janis

Part of Annals of the New York Academy of Sciences, p. 460-463, 2005

Article in journal

• DOI for Unusual genomic structure: melanocortin receptors in fugu

Pharmacological characterization of melanocortin receptors in fish suggests an important role for ACTH

Haitina, Tatjana; Klovins, Janis; Schiöth, Helgi B.

Part of Annals of the New York Academy of Sciences, p. 337-9, 2005

Article in journal

• DOI for Pharmacological characterization of melanocortin receptors in fish suggests an important role for ACTH

Evolutionary conservation of the structural, pharmacological, and genomic characteristics of the melanocortin receptor subtypes

Schiöth, Helgi B; Haitina, Tatjana; Ling, Maria K; Ringholm, Aneta et al.

Part of Peptides, p. 1886-1900, 2005

Article in journal

• DOI for Evolutionary conservation of the structural, pharmacological, and genomic characteristics of the melanocortin receptor subtypes