Sebastian Deindl

Native Mass Spectrometry Captures the Conformational Plasticity of Proteins with Low-Complexity Domains

Osterholz, Hannah; Stevens, Alexander; Abramsson, Mia L.; Lama, Dilraj et al.

Part of JACS Au, p. 281-290, 2025

• DOI for Native Mass Spectrometry Captures the Conformational Plasticity of Proteins with Low-Complexity Domains
• Download full text (pdf) of Native Mass Spectrometry Captures the Conformational Plasticity of Proteins with Low-Complexity Domains

The voyage is as important as the harbor

Sabantsev, Anton; Deindl, Sebastian

Part of eLIFE, 2024

• DOI for The voyage is as important as the harbor
• Download full text (pdf) of The voyage is as important as the harbor

Asymmetric nucleosome PARylation at DNA breaks mediates directional nucleosome sliding by ALC1

Bacic, Luka; Gaullier, Guillaume; Mohapatra, Jugal; Mao, Guanzhong et al.

Part of Nature Communications, 2024

• DOI for Asymmetric nucleosome PARylation at DNA breaks mediates directional nucleosome sliding by ALC1
• Download full text (pdf) of Asymmetric nucleosome PARylation at DNA breaks mediates directional nucleosome sliding by ALC1

Massively parallel analysis of single-molecule dynamics on next-generation sequencing chips

Aguirre Rivera, Javier; Mao, Guanzhong; Sabantsev, Anton; Panfilov, Mikhail et al.

Part of Science, p. 892-898, 2024

• DOI for Massively parallel analysis of single-molecule dynamics on next-generation sequencing chips

Spatiotemporally controlled generation of NTPs for single-molecule studies

Sabantsev, Anton; Mao, Guanzhong; Aguirre, Javier Rivera; Panfilov, Mikhail et al.

Part of Nature Chemical Biology, p. 1144-+, 2022

• DOI for Spatiotemporally controlled generation of NTPs for single-molecule studies
• Download full text (pdf) of Spatiotemporally controlled generation of NTPs for single-molecule studies

Native Mass Spectrometry Captures the Conformational Plasticity of Proteins with Low-Complexity Domains

Osterholz, Hannah; Stevens, Alexander; Abramsson, Mia L.; Lama, Dilraj et al.

Part of JACS Au, p. 281-290, 2025

• DOI for Native Mass Spectrometry Captures the Conformational Plasticity of Proteins with Low-Complexity Domains
• Download full text (pdf) of Native Mass Spectrometry Captures the Conformational Plasticity of Proteins with Low-Complexity Domains

The voyage is as important as the harbor

Sabantsev, Anton; Deindl, Sebastian

Part of eLIFE, 2024

• DOI for The voyage is as important as the harbor
• Download full text (pdf) of The voyage is as important as the harbor

Asymmetric nucleosome PARylation at DNA breaks mediates directional nucleosome sliding by ALC1

Bacic, Luka; Gaullier, Guillaume; Mohapatra, Jugal; Mao, Guanzhong et al.

Part of Nature Communications, 2024

• DOI for Asymmetric nucleosome PARylation at DNA breaks mediates directional nucleosome sliding by ALC1
• Download full text (pdf) of Asymmetric nucleosome PARylation at DNA breaks mediates directional nucleosome sliding by ALC1

Massively parallel analysis of single-molecule dynamics on next-generation sequencing chips

Aguirre Rivera, Javier; Mao, Guanzhong; Sabantsev, Anton; Panfilov, Mikhail et al.

Part of Science, p. 892-898, 2024

• DOI for Massively parallel analysis of single-molecule dynamics on next-generation sequencing chips

Spatiotemporally controlled generation of NTPs for single-molecule studies

Sabantsev, Anton; Mao, Guanzhong; Aguirre, Javier Rivera; Panfilov, Mikhail et al.

Part of Nature Chemical Biology, p. 1144-+, 2022

• DOI for Spatiotemporally controlled generation of NTPs for single-molecule studies
• Download full text (pdf) of Spatiotemporally controlled generation of NTPs for single-molecule studies

ADP-ribosyltransferases, an update on function and nomenclature

Lüscher, Bernhard; Ahel, Ivan; Altmeyer, Matthias; Ashworth, Alan et al.

Part of The FEBS Journal, p. 7399-7410, 2022

• DOI for ADP-ribosyltransferases, an update on function and nomenclature
• Download full text (pdf) of ADP-ribosyltransferases, an update on function and nomenclature

Sequence specificity in DNA binding is mainly governed by association

Marklund, Emil; Mao, Guanzhong; Yuan, Jinwen; Zikrin, Spartak et al.

Part of Science, p. 442-445, 2022

• DOI for Sequence specificity in DNA binding is mainly governed by association
• Download full text (pdf) of Sequence specificity in DNA binding is mainly governed by association

Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome

Bacic, Luka; Gaullier, Guillaume; Sabantsev, Anton; Lehmann, Laura C. et al.

Part of eLIFE, 2021

• DOI for Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome

A unique histone 3 lysine 14 chromatin signature underlies tissue-specific gene regulation

Regadas, Isabel; Dahlberg, Olle; Vaid, Roshan; Ho, Oanh et al.

Part of Molecular Cell, p. 1766-17800000000000, 2021

• DOI for A unique histone 3 lysine 14 chromatin signature underlies tissue-specific gene regulation
• Download full text (pdf) of A unique histone 3 lysine 14 chromatin signature underlies tissue-specific gene regulation

More Than Just Letters and Chemistry: Genomics Goes Mechanics

Deindl, Sebastian; Elf, Johan

Part of TIBS -Trends in Biochemical Sciences. Regular ed., p. 431-432, 2021

• DOI for More Than Just Letters and Chemistry: Genomics Goes Mechanics

Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD

Hewitt, Graeme; Borel, Valerie; Segura-Bayona, Sandra; Takaki, Tohru et al.

Part of Molecular Cell, p. 767-78300000000000, 2021

• DOI for Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD
• Download full text (pdf) of Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD

Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch

Lehmann, Laura C.; Bacic, Luka; Hewitt, Graeme; Brackmann, Klaus et al.

Part of Cell Reports, 2020

• DOI for Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch
• Download full text (pdf) of Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch

DNA surface exploration and operator bypassing during target search

Marklund, Emil; van Oosten, Brad; Mao, Guanzhong; Amselem, Elias et al.

Part of Nature, p. 858-+, 2020

• DOI for DNA surface exploration and operator bypassing during target search
• Download full text (pdf) of DNA surface exploration and operator bypassing during target search

Recent advances in single-molecule fluorescence microscopy render structural biology dynamic

Bacic, Luka; Sabantsev, Anton; Deindl, Sebastian

Part of Current opinion in structural biology, p. 61-68, 2020

• DOI for Recent advances in single-molecule fluorescence microscopy render structural biology dynamic
• Download full text (pdf) of Recent advances in single-molecule fluorescence microscopy render structural biology dynamic

The ribosomal protein S1-dependent standby site in tisB mRNA consists of a single-stranded region and a 5 ' structure element

Romilly, Cedric; Deindl, Sebastian; Wagner, Gerhart E. H.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 15901-15906, 2019

• DOI for The ribosomal protein S1-dependent standby site in tisB mRNA consists of a single-stranded region and a 5 ' structure element
• Download full text (pdf) of The ribosomal protein S1-dependent standby site in tisB mRNA consists of a single-stranded region and a 5 ' structure element

Direct observation of coordinated DNA movements on the nucleosome during chromatin remodelling

Sabantsev, Anton; Levendosky, Robert F.; Zhuang, Xiaowei; Bowman, Gregory D. et al.

Part of Nature Communications, 2019

• DOI for Direct observation of coordinated DNA movements on the nucleosome during chromatin remodelling
• Download full text (pdf) of Direct observation of coordinated DNA movements on the nucleosome during chromatin remodelling

Long Time-Scale Atomistic Simulations of the Structure and Dynamics of Transcription Factor-DNA Recognition

Liao, Qinghua; Lüking, Malin; Krueger, Dennis M.; Deindl, Sebastian et al.

Part of Journal of Physical Chemistry B, p. 3576-3590, 2019

• DOI for Long Time-Scale Atomistic Simulations of the Structure and Dynamics of Transcription Factor-DNA Recognition
• Download full text (pdf) of Long Time-Scale Atomistic Simulations of the Structure and Dynamics of Transcription Factor-DNA Recognition

Remodeling the genome with DNA twists

Bowman, Gregory D.; Deindl, Sebastian

Part of Science, p. 35-36, 2019

• DOI for Remodeling the genome with DNA twists
• Download full text (pdf) of Remodeling the genome with DNA twists

Structure-guided approach to site-specific fluorophore labeling of the lac repressor LacI

Kipper, Kalle; Eremina, Nadja; Marklund, Emil; Tubasum, Sumera et al.

Part of PLOS ONE, 2018

• DOI for Structure-guided approach to site-specific fluorophore labeling of the lac repressor LacI
• Download full text (pdf) of Structure-guided approach to site-specific fluorophore labeling of the lac repressor LacI

New enzymatic and mass spectrometric methodology for the selective investigation of gut microbiota-derived metabolites

Ballet, Caroline; Correia, Mario S. P.; Conway, Louis P.; Locher, Theresa L. et al.

Part of Chemical Science, p. 6233-6239, 2018

• DOI for New enzymatic and mass spectrometric methodology for the selective investigation of gut microbiota-derived metabolites
• Download full text (pdf) of New enzymatic and mass spectrometric methodology for the selective investigation of gut microbiota-derived metabolites

Real- Time Single Protein Tracking with Polarization Readout using a Confocal Microscope

Amselem, Elias; Marklund, Emil; Kipper, Kalle; Johansson, Magnus et al.

Part of Biophysical Journal, 2017

Measuring the Orientation of Single Proteins Interacting with DNA using Fluorescence Polarization Microscopy

Marklund, Emil; Amselem, Elias; Kipper, Kalle; Johansson, Magnus et al.

Part of Biophysical Journal, 2017

Mechanistic Insights into Autoinhibition of the Oncogenic Chromatin Remodeler ALC1

Lehmann, Laura C.; Hewitt, Graeme; Aibara, Shintaro; Leitner, Alexander et al.

Part of Molecular Cell, p. 847-8590000000, 2017

• DOI for Mechanistic Insights into Autoinhibition of the Oncogenic Chromatin Remodeler ALC1
• Download full text (pdf) of Mechanistic Insights into Autoinhibition of the Oncogenic Chromatin Remodeler ALC1

Development of a novel therapeutic vaccine carrier that sustains high antibody titers against several targets simultaneously

Saupe, Falk; Reichel, Matthias; Huijbers, Elisabeth J. M.; Femel, Julia et al.

Part of The FASEB Journal, p. 1204-1214, 2017

• DOI for Development of a novel therapeutic vaccine carrier that sustains high antibody titers against several targets simultaneously

The Chd1 chromatin remodeler shifts hexasomes unidirectionally

Levendosky, Robert F.; Sabantsev, Anton; Deindl, Sebastian; Bowman, Gregory D.

Part of eLIFE, 2016

• DOI for The Chd1 chromatin remodeler shifts hexasomes unidirectionally
• Download full text (pdf) of The Chd1 chromatin remodeler shifts hexasomes unidirectionally

Stepwise nucleosome translocation by RSC remodeling complexes

Harada, Bryan T.; Hwang, William L.; Deindl, Sebastian; Chatterjee, Nilanjana et al.

Part of eLIFE, 2016

• DOI for Stepwise nucleosome translocation by RSC remodeling complexes
• Download full text (pdf) of Stepwise nucleosome translocation by RSC remodeling complexes