Sebastian Deindl

Multiplexed single-molecule characterization at the library scale

Panfilov, Mikhail; Mao, Guanzhong; Guo, Jianfeng; Aguirre Rivera, Javier et al.

Ingår i Nature Protocols, 2025

• DOI för Multiplexed single-molecule characterization at the library scale
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Native Mass Spectrometry Captures the Conformational Plasticity of Proteins with Low-Complexity Domains

Osterholz, Hannah; Stevens, Alexander; Abramsson, Mia L.; Lama, Dilraj et al.

Ingår i JACS Au, s. 281-290, 2025

• DOI för Native Mass Spectrometry Captures the Conformational Plasticity of Proteins with Low-Complexity Domains
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Massively parallel analysis of single-molecule dynamics on next-generation sequencing chips

Aguirre Rivera, Javier; Mao, Guanzhong; Sabantsev, Anton; Panfilov, Mikhail et al.

Ingår i Science, s. 892-898, 2024

• DOI för Massively parallel analysis of single-molecule dynamics on next-generation sequencing chips
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The voyage is as important as the harbor

Sabantsev, Anton; Deindl, Sebastian

Ingår i eLIFE, 2024

• DOI för The voyage is as important as the harbor
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Asymmetric nucleosome PARylation at DNA breaks mediates directional nucleosome sliding by ALC1

Bacic, Luka; Gaullier, Guillaume; Mohapatra, Jugal; Mao, Guanzhong et al.

Ingår i Nature Communications, 2024

• DOI för Asymmetric nucleosome PARylation at DNA breaks mediates directional nucleosome sliding by ALC1
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Native Mass Spectrometry Captures the Conformational Plasticity of Proteins with Low-Complexity Domains

Osterholz, Hannah; Stevens, Alexander; Abramsson, Mia L.; Lama, Dilraj et al.

Ingår i JACS Au, s. 281-290, 2025

• DOI för Native Mass Spectrometry Captures the Conformational Plasticity of Proteins with Low-Complexity Domains
• Ladda ner fulltext (pdf) av Native Mass Spectrometry Captures the Conformational Plasticity of Proteins with Low-Complexity Domains

Massively parallel analysis of single-molecule dynamics on next-generation sequencing chips

Aguirre Rivera, Javier; Mao, Guanzhong; Sabantsev, Anton; Panfilov, Mikhail et al.

Ingår i Science, s. 892-898, 2024

• DOI för Massively parallel analysis of single-molecule dynamics on next-generation sequencing chips
• Ladda ner fulltext (pdf) av Massively parallel analysis of single-molecule dynamics on next-generation sequencing chips

The voyage is as important as the harbor

Sabantsev, Anton; Deindl, Sebastian

Ingår i eLIFE, 2024

• DOI för The voyage is as important as the harbor
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Asymmetric nucleosome PARylation at DNA breaks mediates directional nucleosome sliding by ALC1

Bacic, Luka; Gaullier, Guillaume; Mohapatra, Jugal; Mao, Guanzhong et al.

Ingår i Nature Communications, 2024

• DOI för Asymmetric nucleosome PARylation at DNA breaks mediates directional nucleosome sliding by ALC1
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Sequence specificity in DNA binding is mainly governed by association

Marklund, Emil; Mao, Guanzhong; Yuan, Jinwen; Zikrin, Spartak et al.

Ingår i Science, s. 442-445, 2022

• DOI för Sequence specificity in DNA binding is mainly governed by association
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Spatiotemporally controlled generation of NTPs for single-molecule studies

Sabantsev, Anton; Mao, Guanzhong; Aguirre, Javier Rivera; Panfilov, Mikhail et al.

Ingår i Nature Chemical Biology, s. 1144-+, 2022

• DOI för Spatiotemporally controlled generation of NTPs for single-molecule studies
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ADP-ribosyltransferases, an update on function and nomenclature

Lüscher, Bernhard; Ahel, Ivan; Altmeyer, Matthias; Ashworth, Alan et al.

Ingår i The FEBS Journal, s. 7399-7410, 2022

• DOI för ADP-ribosyltransferases, an update on function and nomenclature
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Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome

Bacic, Luka; Gaullier, Guillaume; Sabantsev, Anton; Lehmann, Laura C. et al.

Ingår i eLIFE, 2021

• DOI för Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome

A unique histone 3 lysine 14 chromatin signature underlies tissue-specific gene regulation

Regadas, Isabel; Dahlberg, Olle; Vaid, Roshan; Ho, Oanh et al.

Ingår i Molecular Cell, s. 1766-17800000000000, 2021

• DOI för A unique histone 3 lysine 14 chromatin signature underlies tissue-specific gene regulation
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More Than Just Letters and Chemistry: Genomics Goes Mechanics

Deindl, Sebastian; Elf, Johan

Ingår i TIBS -Trends in Biochemical Sciences. Regular ed., s. 431-432, 2021

• DOI för More Than Just Letters and Chemistry: Genomics Goes Mechanics

Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD

Hewitt, Graeme; Borel, Valerie; Segura-Bayona, Sandra; Takaki, Tohru et al.

Ingår i Molecular Cell, s. 767-78300000000000, 2021

• DOI för Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD
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Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch

Lehmann, Laura C.; Bacic, Luka; Hewitt, Graeme; Brackmann, Klaus et al.

Ingår i Cell Reports, 2020

• DOI för Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch
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Recent advances in single-molecule fluorescence microscopy render structural biology dynamic

Bacic, Luka; Sabantsev, Anton; Deindl, Sebastian

Ingår i Current opinion in structural biology, s. 61-68, 2020

• DOI för Recent advances in single-molecule fluorescence microscopy render structural biology dynamic
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DNA surface exploration and operator bypassing during target search

Marklund, Emil; van Oosten, Brad; Mao, Guanzhong; Amselem, Elias et al.

Ingår i Nature, s. 858-+, 2020

• DOI för DNA surface exploration and operator bypassing during target search
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The ribosomal protein S1-dependent standby site in tisB mRNA consists of a single-stranded region and a 5 ' structure element

Romilly, Cedric; Deindl, Sebastian; Wagner, Gerhart E. H.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 15901-15906, 2019

• DOI för The ribosomal protein S1-dependent standby site in tisB mRNA consists of a single-stranded region and a 5 ' structure element
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Long Time-Scale Atomistic Simulations of the Structure and Dynamics of Transcription Factor-DNA Recognition

Liao, Qinghua; Lüking, Malin; Krueger, Dennis M.; Deindl, Sebastian et al.

Ingår i Journal of Physical Chemistry B, s. 3576-3590, 2019

• DOI för Long Time-Scale Atomistic Simulations of the Structure and Dynamics of Transcription Factor-DNA Recognition
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Direct observation of coordinated DNA movements on the nucleosome during chromatin remodelling

Sabantsev, Anton; Levendosky, Robert F.; Zhuang, Xiaowei; Bowman, Gregory D. et al.

Ingår i Nature Communications, 2019

• DOI för Direct observation of coordinated DNA movements on the nucleosome during chromatin remodelling
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Remodeling the genome with DNA twists

Bowman, Gregory D.; Deindl, Sebastian

Ingår i Science, s. 35-36, 2019

• DOI för Remodeling the genome with DNA twists
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New enzymatic and mass spectrometric methodology for the selective investigation of gut microbiota-derived metabolites

Ballet, Caroline; Correia, Mario S. P.; Conway, Louis P.; Locher, Theresa L. et al.

Ingår i Chemical Science, s. 6233-6239, 2018

• DOI för New enzymatic and mass spectrometric methodology for the selective investigation of gut microbiota-derived metabolites
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Structure-guided approach to site-specific fluorophore labeling of the lac repressor LacI

Kipper, Kalle; Eremina, Nadja; Marklund, Emil; Tubasum, Sumera et al.

Ingår i PLOS ONE, 2018

• DOI för Structure-guided approach to site-specific fluorophore labeling of the lac repressor LacI
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Real- Time Single Protein Tracking with Polarization Readout using a Confocal Microscope

Amselem, Elias; Marklund, Emil; Kipper, Kalle; Johansson, Magnus et al.

Ingår i Biophysical Journal, 2017

Measuring the Orientation of Single Proteins Interacting with DNA using Fluorescence Polarization Microscopy

Marklund, Emil; Amselem, Elias; Kipper, Kalle; Johansson, Magnus et al.

Ingår i Biophysical Journal, 2017

Mechanistic Insights into Autoinhibition of the Oncogenic Chromatin Remodeler ALC1

Lehmann, Laura C.; Hewitt, Graeme; Aibara, Shintaro; Leitner, Alexander et al.

Ingår i Molecular Cell, s. 847-8590000000, 2017

• DOI för Mechanistic Insights into Autoinhibition of the Oncogenic Chromatin Remodeler ALC1
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Development of a novel therapeutic vaccine carrier that sustains high antibody titers against several targets simultaneously

Saupe, Falk; Reichel, Matthias; Huijbers, Elisabeth J. M.; Femel, Julia et al.

Ingår i The FASEB Journal, s. 1204-1214, 2017

• DOI för Development of a novel therapeutic vaccine carrier that sustains high antibody titers against several targets simultaneously

The Chd1 chromatin remodeler shifts hexasomes unidirectionally

Levendosky, Robert F.; Sabantsev, Anton; Deindl, Sebastian; Bowman, Gregory D.

Ingår i eLIFE, 2016

• DOI för The Chd1 chromatin remodeler shifts hexasomes unidirectionally
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Stepwise nucleosome translocation by RSC remodeling complexes

Harada, Bryan T.; Hwang, William L.; Deindl, Sebastian; Chatterjee, Nilanjana et al.

Ingår i eLIFE, 2016

• DOI för Stepwise nucleosome translocation by RSC remodeling complexes
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Multiplexed single-molecule characterization at the library scale

Panfilov, Mikhail; Mao, Guanzhong; Guo, Jianfeng; Aguirre Rivera, Javier et al.

Ingår i Nature Protocols, 2025

• DOI för Multiplexed single-molecule characterization at the library scale
• Ladda ner fulltext (pdf) av Multiplexed single-molecule characterization at the library scale