Sebastian Deindl

Stability and reliability of carbon-coated solid-state nanopores for single molecule analysis

Liu, Funing; Wen, Chenyu; Deindl, Sebastian; Zhang, Zhen

Ingår i Nanotechnology, 2026

• DOI för Stability and reliability of carbon-coated solid-state nanopores for single molecule analysis
• Ladda ner fulltext (pdf) av Stability and reliability of carbon-coated solid-state nanopores for single molecule analysis

Cryo-EM structure of ALC1 in an open conformation bound to a PARylated nucleosome

Bridges, Hannah R.; Bacic, Luka; Deindl, Sebastian; Gaullier, Guillaume

Ingår i Acta Crystallographica Section D, s. 683-699, 2026

• DOI för Cryo-EM structure of ALC1 in an open conformation bound to a PARylated nucleosome
• Ladda ner fulltext (pdf) av Cryo-EM structure of ALC1 in an open conformation bound to a PARylated nucleosome

A Nanopore-Gated Subattoliter Silicon Nanocavity for Single-Molecule Trapping and Analysis without Applying an External Force

Liu, Funing; Hu, Qitao; Sabantsev, Anton; Di Muccio, Giovanni et al.

Ingår i ACS Nano, 2026

• DOI för A Nanopore-Gated Subattoliter Silicon Nanocavity for Single-Molecule Trapping and Analysis without Applying an External Force
• Ladda ner fulltext (pdf) av A Nanopore-Gated Subattoliter Silicon Nanocavity for Single-Molecule Trapping and Analysis without Applying an External Force

Multiplexed single-molecule characterization at the library scale

Panfilov, Mikhail; Mao, Guanzhong; Guo, Jianfeng; Aguirre Rivera, Javier et al.

Ingår i Nature Protocols, s. 749-774, 2026

• DOI för Multiplexed single-molecule characterization at the library scale
• Ladda ner fulltext (pdf) av Multiplexed single-molecule characterization at the library scale

The human BAF chromatin remodeler processes nucleosomes bound by pioneer transcription factors OCT4-SOX2

Weiss, Joscha; Vecchia, Luca; Domjan, David; Cavadini, Simone et al.

Ingår i Molecular Cell, s. 625-63900000000, 2026

• DOI för The human BAF chromatin remodeler processes nucleosomes bound by pioneer transcription factors OCT4-SOX2
• Ladda ner fulltext (pdf) av The human BAF chromatin remodeler processes nucleosomes bound by pioneer transcription factors OCT4-SOX2

Stability and reliability of carbon-coated solid-state nanopores for single molecule analysis

Liu, Funing; Wen, Chenyu; Deindl, Sebastian; Zhang, Zhen

Ingår i Nanotechnology, 2026

• DOI för Stability and reliability of carbon-coated solid-state nanopores for single molecule analysis
• Ladda ner fulltext (pdf) av Stability and reliability of carbon-coated solid-state nanopores for single molecule analysis

Cryo-EM structure of ALC1 in an open conformation bound to a PARylated nucleosome

Bridges, Hannah R.; Bacic, Luka; Deindl, Sebastian; Gaullier, Guillaume

Ingår i Acta Crystallographica Section D, s. 683-699, 2026

• DOI för Cryo-EM structure of ALC1 in an open conformation bound to a PARylated nucleosome
• Ladda ner fulltext (pdf) av Cryo-EM structure of ALC1 in an open conformation bound to a PARylated nucleosome

A Nanopore-Gated Subattoliter Silicon Nanocavity for Single-Molecule Trapping and Analysis without Applying an External Force

Liu, Funing; Hu, Qitao; Sabantsev, Anton; Di Muccio, Giovanni et al.

Ingår i ACS Nano, 2026

• DOI för A Nanopore-Gated Subattoliter Silicon Nanocavity for Single-Molecule Trapping and Analysis without Applying an External Force
• Ladda ner fulltext (pdf) av A Nanopore-Gated Subattoliter Silicon Nanocavity for Single-Molecule Trapping and Analysis without Applying an External Force

The human BAF chromatin remodeler processes nucleosomes bound by pioneer transcription factors OCT4-SOX2

Weiss, Joscha; Vecchia, Luca; Domjan, David; Cavadini, Simone et al.

Ingår i Molecular Cell, s. 625-63900000000, 2026

• DOI för The human BAF chromatin remodeler processes nucleosomes bound by pioneer transcription factors OCT4-SOX2
• Ladda ner fulltext (pdf) av The human BAF chromatin remodeler processes nucleosomes bound by pioneer transcription factors OCT4-SOX2

Native Mass Spectrometry Captures the Conformational Plasticity of Proteins with Low-Complexity Domains

Osterholz, Hannah; Stevens, Alexander; Abramsson, Mia L.; Lama, Dilraj et al.

Ingår i JACS Au, s. 281-290, 2025

• DOI för Native Mass Spectrometry Captures the Conformational Plasticity of Proteins with Low-Complexity Domains
• Ladda ner fulltext (pdf) av Native Mass Spectrometry Captures the Conformational Plasticity of Proteins with Low-Complexity Domains

Massively parallel analysis of single-molecule dynamics on next-generation sequencing chips

Aguirre Rivera, Javier; Mao, Guanzhong; Sabantsev, Anton; Panfilov, Mikhail et al.

Ingår i Science, s. 892-898, 2024

• DOI för Massively parallel analysis of single-molecule dynamics on next-generation sequencing chips
• Ladda ner fulltext (pdf) av Massively parallel analysis of single-molecule dynamics on next-generation sequencing chips

Asymmetric nucleosome PARylation at DNA breaks mediates directional nucleosome sliding by ALC1

Bacic, Luka; Gaullier, Guillaume; Mohapatra, Jugal; Mao, Guanzhong et al.

Ingår i Nature Communications, 2024

• DOI för Asymmetric nucleosome PARylation at DNA breaks mediates directional nucleosome sliding by ALC1
• Ladda ner fulltext (pdf) av Asymmetric nucleosome PARylation at DNA breaks mediates directional nucleosome sliding by ALC1

The voyage is as important as the harbor

Sabantsev, Anton; Deindl, Sebastian

Ingår i eLIFE, 2024

• DOI för The voyage is as important as the harbor
• Ladda ner fulltext (pdf) av The voyage is as important as the harbor

Sequence specificity in DNA binding is mainly governed by association

Marklund, Emil; Mao, Guanzhong; Yuan, Jinwen; Zikrin, Spartak et al.

Ingår i Science, s. 442-445, 2022

• DOI för Sequence specificity in DNA binding is mainly governed by association
• Ladda ner fulltext (pdf) av Sequence specificity in DNA binding is mainly governed by association

Spatiotemporally controlled generation of NTPs for single-molecule studies

Sabantsev, Anton; Mao, Guanzhong; Aguirre, Javier Rivera; Panfilov, Mikhail et al.

Ingår i Nature Chemical Biology, s. 1144-+, 2022

• DOI för Spatiotemporally controlled generation of NTPs for single-molecule studies
• Ladda ner fulltext (pdf) av Spatiotemporally controlled generation of NTPs for single-molecule studies

ADP-ribosyltransferases, an update on function and nomenclature

Lüscher, Bernhard; Ahel, Ivan; Altmeyer, Matthias; Ashworth, Alan et al.

Ingår i The FEBS Journal, s. 7399-7410, 2022

• DOI för ADP-ribosyltransferases, an update on function and nomenclature
• Ladda ner fulltext (pdf) av ADP-ribosyltransferases, an update on function and nomenclature

Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome

Bacic, Luka; Gaullier, Guillaume; Sabantsev, Anton; Lehmann, Laura C. et al.

Ingår i eLIFE, 2021

• DOI för Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome

More Than Just Letters and Chemistry: Genomics Goes Mechanics

Deindl, Sebastian; Elf, Johan

Ingår i TIBS -Trends in Biochemical Sciences. Regular ed., s. 431-432, 2021

• DOI för More Than Just Letters and Chemistry: Genomics Goes Mechanics

A unique histone 3 lysine 14 chromatin signature underlies tissue-specific gene regulation

Regadas, Isabel; Dahlberg, Olle; Vaid, Roshan; Ho, Oanh et al.

Ingår i Molecular Cell, s. 1766-17800000000000, 2021

• DOI för A unique histone 3 lysine 14 chromatin signature underlies tissue-specific gene regulation
• Ladda ner fulltext (pdf) av A unique histone 3 lysine 14 chromatin signature underlies tissue-specific gene regulation

Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD

Hewitt, Graeme; Borel, Valerie; Segura-Bayona, Sandra; Takaki, Tohru et al.

Ingår i Molecular Cell, s. 767-78300000000000, 2021

• DOI för Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD
• Ladda ner fulltext (pdf) av Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD

Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch

Lehmann, Laura C.; Bacic, Luka; Hewitt, Graeme; Brackmann, Klaus et al.

Ingår i Cell Reports, 2020

• DOI för Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch
• Ladda ner fulltext (pdf) av Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch

Recent advances in single-molecule fluorescence microscopy render structural biology dynamic

Bacic, Luka; Sabantsev, Anton; Deindl, Sebastian

Ingår i Current opinion in structural biology, s. 61-68, 2020

• DOI för Recent advances in single-molecule fluorescence microscopy render structural biology dynamic
• Ladda ner fulltext (pdf) av Recent advances in single-molecule fluorescence microscopy render structural biology dynamic

DNA surface exploration and operator bypassing during target search

Marklund, Emil; van Oosten, Brad; Mao, Guanzhong; Amselem, Elias et al.

Ingår i Nature, s. 858-+, 2020

• DOI för DNA surface exploration and operator bypassing during target search
• Ladda ner fulltext (pdf) av DNA surface exploration and operator bypassing during target search

Direct observation of coordinated DNA movements on the nucleosome during chromatin remodelling

Sabantsev, Anton; Levendosky, Robert F.; Zhuang, Xiaowei; Bowman, Gregory D. et al.

Ingår i Nature Communications, 2019

• DOI för Direct observation of coordinated DNA movements on the nucleosome during chromatin remodelling
• Ladda ner fulltext (pdf) av Direct observation of coordinated DNA movements on the nucleosome during chromatin remodelling

The ribosomal protein S1-dependent standby site in tisB mRNA consists of a single-stranded region and a 5 ' structure element

Romilly, Cedric; Deindl, Sebastian; Wagner, Gerhart E. H.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 15901-15906, 2019

• DOI för The ribosomal protein S1-dependent standby site in tisB mRNA consists of a single-stranded region and a 5 ' structure element
• Ladda ner fulltext (pdf) av The ribosomal protein S1-dependent standby site in tisB mRNA consists of a single-stranded region and a 5 ' structure element

Long Time-Scale Atomistic Simulations of the Structure and Dynamics of Transcription Factor-DNA Recognition

Liao, Qinghua; Lüking, Malin; Krueger, Dennis M.; Deindl, Sebastian et al.

Ingår i Journal of Physical Chemistry B, s. 3576-3590, 2019

• DOI för Long Time-Scale Atomistic Simulations of the Structure and Dynamics of Transcription Factor-DNA Recognition
• Ladda ner fulltext (pdf) av Long Time-Scale Atomistic Simulations of the Structure and Dynamics of Transcription Factor-DNA Recognition

Remodeling the genome with DNA twists

Bowman, Gregory D.; Deindl, Sebastian

Ingår i Science, s. 35-36, 2019

• DOI för Remodeling the genome with DNA twists
• Ladda ner fulltext (pdf) av Remodeling the genome with DNA twists

New enzymatic and mass spectrometric methodology for the selective investigation of gut microbiota-derived metabolites

Ballet, Caroline; Correia, Mario S. P.; Conway, Louis P.; Locher, Theresa L. et al.

Ingår i Chemical Science, s. 6233-6239, 2018

• DOI för New enzymatic and mass spectrometric methodology for the selective investigation of gut microbiota-derived metabolites
• Ladda ner fulltext (pdf) av New enzymatic and mass spectrometric methodology for the selective investigation of gut microbiota-derived metabolites

Structure-guided approach to site-specific fluorophore labeling of the lac repressor LacI

Kipper, Kalle; Eremina, Nadja; Marklund, Emil; Tubasum, Sumera et al.

Ingår i PLOS ONE, 2018

• DOI för Structure-guided approach to site-specific fluorophore labeling of the lac repressor LacI
• Ladda ner fulltext (pdf) av Structure-guided approach to site-specific fluorophore labeling of the lac repressor LacI

Measuring the Orientation of Single Proteins Interacting with DNA using Fluorescence Polarization Microscopy

Marklund, Emil; Amselem, Elias; Kipper, Kalle; Johansson, Magnus et al.

Ingår i Biophysical Journal, 2017

Real- Time Single Protein Tracking with Polarization Readout using a Confocal Microscope

Amselem, Elias; Marklund, Emil; Kipper, Kalle; Johansson, Magnus et al.

Ingår i Biophysical Journal, 2017

Mechanistic Insights into Autoinhibition of the Oncogenic Chromatin Remodeler ALC1

Lehmann, Laura C.; Hewitt, Graeme; Aibara, Shintaro; Leitner, Alexander et al.

Ingår i Molecular Cell, s. 847-8590000000, 2017

• DOI för Mechanistic Insights into Autoinhibition of the Oncogenic Chromatin Remodeler ALC1
• Ladda ner fulltext (pdf) av Mechanistic Insights into Autoinhibition of the Oncogenic Chromatin Remodeler ALC1

Development of a novel therapeutic vaccine carrier that sustains high antibody titers against several targets simultaneously

Saupe, Falk; Reichel, Matthias; Huijbers, Elisabeth J. M.; Femel, Julia et al.

Ingår i The FASEB Journal, s. 1204-1214, 2017

• DOI för Development of a novel therapeutic vaccine carrier that sustains high antibody titers against several targets simultaneously

The Chd1 chromatin remodeler shifts hexasomes unidirectionally

Levendosky, Robert F.; Sabantsev, Anton; Deindl, Sebastian; Bowman, Gregory D.

Ingår i eLIFE, 2016

• DOI för The Chd1 chromatin remodeler shifts hexasomes unidirectionally
• Ladda ner fulltext (pdf) av The Chd1 chromatin remodeler shifts hexasomes unidirectionally

Stepwise nucleosome translocation by RSC remodeling complexes

Harada, Bryan T.; Hwang, William L.; Deindl, Sebastian; Chatterjee, Nilanjana et al.

Ingår i eLIFE, 2016

• DOI för Stepwise nucleosome translocation by RSC remodeling complexes
• Ladda ner fulltext (pdf) av Stepwise nucleosome translocation by RSC remodeling complexes

Multiplexed single-molecule characterization at the library scale

Panfilov, Mikhail; Mao, Guanzhong; Guo, Jianfeng; Aguirre Rivera, Javier et al.

Ingår i Nature Protocols, s. 749-774, 2026

• DOI för Multiplexed single-molecule characterization at the library scale
• Ladda ner fulltext (pdf) av Multiplexed single-molecule characterization at the library scale

From sequence to function: Bridging single-molecule kinetics and molecular diversity

Kapanidis, A. N.; Muras, Laura; Sreenivasa, K.; Hazra, J. P. et al.

Ingår i Science, s. 458-465, 2026

• DOI för From sequence to function: Bridging single-molecule kinetics and molecular diversity