Wen Liu
Staff scientist at Department of Surgical Sciences; Medical epidemiology
- E-mail:
- wen.liu@uu.se
- Visiting address:
- Epihubben, Dag Hammarskjölds väg 14 B
75185 Uppsala - Postal address:
- Epihubben, MTC-huset
75185 Uppsala
Download contact information for Wen Liu at Department of Surgical Sciences; Medical epidemiology
Short presentation
Associate Professor in Cancer Epidemiology. My research focuses on genetic and environmental determinants of cancer, especially breast, endometrial and colorectal cancer. I apply molecular epidemiology and statistical genetics, including haplotype-based genome-wide analyses, to study cancer susceptibility, gene–environment interactions, and factors influencing disease progression and treatment response using population-based cohorts. I am also a research infrastructure specialist within SIMPLER.
Keywords
- Cancer epidemiology
- Molecular epidemiology
- Genetic epidemiology
- Statistical genetics
- Genome-wide association studies (GWAS)
- Haplotype-based analysis
- Genetic susceptibility
- Gene–environment interactions
- Environmental exposures
- Breast cancer
- Endometrial cancer
- Colorectal cancer
- Population-based cohorts
- Biobank-based research

Publications
Recent publications
-
Part of Science of the Total Environment, 2025
- DOI for Extensive analysis of pollutant interactions: Identification of deleterious synergistic effects at environmentally relevant dose levels using Drosophila and mammalian cells
- Download full text (pdf) of Extensive analysis of pollutant interactions: Identification of deleterious synergistic effects at environmentally relevant dose levels using Drosophila and mammalian cells
-
Part of International Journal of Molecular Sciences, 2025
- DOI for Novel Shared Heritable Candidate Risk Loci of Breast and Endometrial Cancer-A Swedish Haplotype Genome-Wide Association Study
- Download full text (pdf) of Novel Shared Heritable Candidate Risk Loci of Breast and Endometrial Cancer-A Swedish Haplotype Genome-Wide Association Study
-
Part of PLOS ONE, 2025
- DOI for A Swedish genome-wide haplotype association analysis identifies novel candidate loci associated with endometrial cancer risk
- Download full text (pdf) of A Swedish genome-wide haplotype association analysis identifies novel candidate loci associated with endometrial cancer risk
-
A Haplotype GWAS in Syndromic Familial Colorectal Cancer
Part of International Journal of Molecular Sciences, 2025
- DOI for A Haplotype GWAS in Syndromic Familial Colorectal Cancer
- Download full text (pdf) of A Haplotype GWAS in Syndromic Familial Colorectal Cancer
-
Part of Science of the Total Environment, 2024
- DOI for Perfluorooctanoic acid induces transgenerational modifications in reproduction, metabolism, locomotor activity, and sleep behavior in Drosophila melanogaster and deleterious effects in human cancer cells
- Download full text (pdf) of Perfluorooctanoic acid induces transgenerational modifications in reproduction, metabolism, locomotor activity, and sleep behavior in Drosophila melanogaster and deleterious effects in human cancer cells
All publications
Articles in journal
-
Part of Science of the Total Environment, 2025
- DOI for Extensive analysis of pollutant interactions: Identification of deleterious synergistic effects at environmentally relevant dose levels using Drosophila and mammalian cells
- Download full text (pdf) of Extensive analysis of pollutant interactions: Identification of deleterious synergistic effects at environmentally relevant dose levels using Drosophila and mammalian cells
-
Part of International Journal of Molecular Sciences, 2025
- DOI for Novel Shared Heritable Candidate Risk Loci of Breast and Endometrial Cancer-A Swedish Haplotype Genome-Wide Association Study
- Download full text (pdf) of Novel Shared Heritable Candidate Risk Loci of Breast and Endometrial Cancer-A Swedish Haplotype Genome-Wide Association Study
-
Part of PLOS ONE, 2025
- DOI for A Swedish genome-wide haplotype association analysis identifies novel candidate loci associated with endometrial cancer risk
- Download full text (pdf) of A Swedish genome-wide haplotype association analysis identifies novel candidate loci associated with endometrial cancer risk
-
A Haplotype GWAS in Syndromic Familial Colorectal Cancer
Part of International Journal of Molecular Sciences, 2025
- DOI for A Haplotype GWAS in Syndromic Familial Colorectal Cancer
- Download full text (pdf) of A Haplotype GWAS in Syndromic Familial Colorectal Cancer
-
Part of Science of the Total Environment, 2024
- DOI for Perfluorooctanoic acid induces transgenerational modifications in reproduction, metabolism, locomotor activity, and sleep behavior in Drosophila melanogaster and deleterious effects in human cancer cells
- Download full text (pdf) of Perfluorooctanoic acid induces transgenerational modifications in reproduction, metabolism, locomotor activity, and sleep behavior in Drosophila melanogaster and deleterious effects in human cancer cells
-
Part of Hereditary Cancer in Clinical Practice, 2024
- DOI for A genome-wide association study in Swedish colorectal cancer patients with gastric- and prostate cancer in relatives
- Download full text (pdf) of A genome-wide association study in Swedish colorectal cancer patients with gastric- and prostate cancer in relatives
-
Part of British Journal of Pharmacology, p. 2750-2773, 2024
- DOI for Hydroxymethylglutaryl-CoA reductase activity is essential for mitochondrial β-oxidation of fatty acids to prevent lethal accumulation of long-chain acylcarnitines in the mouse liver
- Download full text (pdf) of Hydroxymethylglutaryl-CoA reductase activity is essential for mitochondrial β-oxidation of fatty acids to prevent lethal accumulation of long-chain acylcarnitines in the mouse liver
-
Part of Genes, 2024
- DOI for Swedish Genome-Wide Haplotype Association Analysis Suggests Breast Cancer Loci with Varying Risk-Modifying Effects
- Download full text (pdf) of Swedish Genome-Wide Haplotype Association Analysis Suggests Breast Cancer Loci with Varying Risk-Modifying Effects
-
Part of Science of the Total Environment, 2024
-
Part of Journal of Applied Toxicology, p. 458-469, 2023
- DOI for Interaction between environmental pollutants and cancer drug efficacy: Bisphenol A, Bisphenol A diglycidyl ether and Perfluorooctanoic acid reduce vincristine cytotoxicity in acute lymphoblastic leukemia cells
- Download full text (pdf) of Interaction between environmental pollutants and cancer drug efficacy: Bisphenol A, Bisphenol A diglycidyl ether and Perfluorooctanoic acid reduce vincristine cytotoxicity in acute lymphoblastic leukemia cells
-
Part of Clinica Chimica Acta, 2023
- DOI for Identification and validation of volatile organic compounds in bile for differential diagnosis of perihilar cholangiocarcinoma
- Download full text (pdf) of Identification and validation of volatile organic compounds in bile for differential diagnosis of perihilar cholangiocarcinoma
-
Part of International Journal of Molecular Sciences, 2023
- DOI for A Swedish Familial Genome-Wide Haplotype Analysis Identified Five Novel Breast Cancer Susceptibility Loci on 9p24.3, 11q22.3, 15q11.2, 16q24.1 and Xq21.31
- Download full text (pdf) of A Swedish Familial Genome-Wide Haplotype Analysis Identified Five Novel Breast Cancer Susceptibility Loci on 9p24.3, 11q22.3, 15q11.2, 16q24.1 and Xq21.31
-
Part of Biomedicines, 2022
- DOI for Generation of Endogenous Promoter-Driven Luciferase Reporter System Using CRISPR/Cas9 for Investigating Transcriptional Regulation of the Core Clock Gene BMAL1
- Download full text (pdf) of Generation of Endogenous Promoter-Driven Luciferase Reporter System Using CRISPR/Cas9 for Investigating Transcriptional Regulation of the Core Clock Gene BMAL1
-
Part of Cancers, 2022
- DOI for A Swedish Genome-Wide Haplotype Association Analysis Identifies a Novel Breast Cancer Susceptibility Locus in 8p21.2 and Characterizes Three Loci on Chromosomes 10, 11 and 16
- Download full text (pdf) of A Swedish Genome-Wide Haplotype Association Analysis Identifies a Novel Breast Cancer Susceptibility Locus in 8p21.2 and Characterizes Three Loci on Chromosomes 10, 11 and 16
-
Colorectal cancer risk susceptibility loci in a Swedish population
Part of Molecular Carcinogenesis, p. 288-300, 2022
- DOI for Colorectal cancer risk susceptibility loci in a Swedish population
- Download full text (pdf) of Colorectal cancer risk susceptibility loci in a Swedish population
-
Part of Molecules, 2022
- DOI for Enhanced Toxicity of Bisphenols Together with UV Filters in Water: Identification of Synergy and Antagonism in Three-Component Mixtures
- Download full text (pdf) of Enhanced Toxicity of Bisphenols Together with UV Filters in Water: Identification of Synergy and Antagonism in Three-Component Mixtures
-
Part of International Journal of Environmental Research and Public Health, p. 2064-2064, 2022
- DOI for Can Exposure to Environmental Pollutants Be Associated with Less Effective Chemotherapy in Cancer Patients?
- Download full text (pdf) of Can Exposure to Environmental Pollutants Be Associated with Less Effective Chemotherapy in Cancer Patients?
-
Part of Membranes, 2021
- DOI for Multidrug Resistance Like Protein 1 Activity in Malpighian Tubules Regulates Lipid Homeostasis in Drosophila
- Download full text (pdf) of Multidrug Resistance Like Protein 1 Activity in Malpighian Tubules Regulates Lipid Homeostasis in Drosophila
-
Dibutyl phthalate disrupts conserved circadian rhythm in Drosophila and human cells
Part of Science of the Total Environment, 2021
- DOI for Dibutyl phthalate disrupts conserved circadian rhythm in Drosophila and human cells
- Download full text (pdf) of Dibutyl phthalate disrupts conserved circadian rhythm in Drosophila and human cells
-
Part of Science of the Total Environment, 2021
Articles, review/survey
-
Part of Basic & Clinical Pharmacology & Toxicology, p. 130-141, 2023
- DOI for The effect of sunscreen 4-methylbenzylidene camphor in different and reproductive models, its bioaccumulation and molecular effects on ligand-receptor interaction, and protein expression
- Download full text (pdf) of The effect of sunscreen 4-methylbenzylidene camphor in different and reproductive models, its bioaccumulation and molecular effects on ligand-receptor interaction, and protein expression
-
Part of Critical reviews in environmental science and technology, p. 4094-4112, 2022
- DOI for The potential interaction of environmental pollutants and circadian rhythm regulations that may cause leukemia
- Download full text (pdf) of The potential interaction of environmental pollutants and circadian rhythm regulations that may cause leukemia
-
Part of Frontiers in Pharmacology, 2022
- DOI for Recent developments of phosphodiesterase inhibitors: Clinical trials, emerging indications and novel molecules
- Download full text (pdf) of Recent developments of phosphodiesterase inhibitors: Clinical trials, emerging indications and novel molecules