Aleksandr Sokolov
Postdoctoral position at Department of Surgical Sciences; Functional Pharmacology and neuroscience
- E-mail:
- aleksandr.sokolov@uu.se
- Visiting address:
- BMC, Husargatan 3
751 24 Uppsala - Postal address:
- Kirurgiska vetenskaper, Box 593
751 24 Uppsala
Biography
Research
During my PhD I studied associations between a person's genetic and epigenetic profile and propensity to develop psychiatric disorders.
Currently, my research area includes using bioinformatic methods and developing machine learning algorithms for applications in psychiatric disorders, drug discovery and clinical trials, as well as other neuroscience projects. Additionally, I am interested in using LLMs for medical data analysis and annotation.

Publications
Selection of publications
Trends in kinase drug discovery: targets, indications and inhibitor design
Part of Nature reviews. Drug discovery, p. 839-861, 2021
Brain Cancer Drug Discovery: Clinical Trials, Drug Classes, Targets, and Combinatorial Therapies
Part of Pharmacological Reviews, p. 1-32, 2021
- DOI for Brain Cancer Drug Discovery: Clinical Trials, Drug Classes, Targets, and Combinatorial Therapies
- Download full text (pdf) of Brain Cancer Drug Discovery: Clinical Trials, Drug Classes, Targets, and Combinatorial Therapies
Recent publications
GPCR drug discovery: new agents, targets and indications
Part of Nature reviews. Drug discovery, 2025
Part of Diabetes, obesity and metabolism, p. 4734-4743, 2024
- DOI for LEAP2 is associated with impulsivity and reward sensitivity depending on the nutritional status and decreases with protein intake in humans
- Download full text (pdf) of LEAP2 is associated with impulsivity and reward sensitivity depending on the nutritional status and decreases with protein intake in humans
Part of Journal of Molecular Neuroscience, 2024
- DOI for Genomic Validation in the UK Biobank Cohort Suggests a Role of C8B and MFG-E8 in the Pathogenesis of Trigeminal Neuralgia
- Download full text (pdf) of Genomic Validation in the UK Biobank Cohort Suggests a Role of C8B and MFG-E8 in the Pathogenesis of Trigeminal Neuralgia
Part of Translational Psychiatry, 2024
- DOI for Depression clinical trials worldwide: a systematic analysis of the ICTRP and comparison with ClinicalTrials.gov
- Download full text (pdf) of Depression clinical trials worldwide: a systematic analysis of the ICTRP and comparison with ClinicalTrials.gov
Depression proteomic profiling in adolescents with transcriptome analyses in independent cohorts
Part of Frontiers in Psychiatry, 2024
- DOI for Depression proteomic profiling in adolescents with transcriptome analyses in independent cohorts
- Download full text (pdf) of Depression proteomic profiling in adolescents with transcriptome analyses in independent cohorts
All publications
Articles in journal
GPCR drug discovery: new agents, targets and indications
Part of Nature reviews. Drug discovery, 2025
Part of Diabetes, obesity and metabolism, p. 4734-4743, 2024
- DOI for LEAP2 is associated with impulsivity and reward sensitivity depending on the nutritional status and decreases with protein intake in humans
- Download full text (pdf) of LEAP2 is associated with impulsivity and reward sensitivity depending on the nutritional status and decreases with protein intake in humans
Part of Journal of Molecular Neuroscience, 2024
- DOI for Genomic Validation in the UK Biobank Cohort Suggests a Role of C8B and MFG-E8 in the Pathogenesis of Trigeminal Neuralgia
- Download full text (pdf) of Genomic Validation in the UK Biobank Cohort Suggests a Role of C8B and MFG-E8 in the Pathogenesis of Trigeminal Neuralgia
Depression proteomic profiling in adolescents with transcriptome analyses in independent cohorts
Part of Frontiers in Psychiatry, 2024
- DOI for Depression proteomic profiling in adolescents with transcriptome analyses in independent cohorts
- Download full text (pdf) of Depression proteomic profiling in adolescents with transcriptome analyses in independent cohorts
Part of European Journal of Pain, p. 929-942, 2024
- DOI for Exploring biomarkers in trigeminal neuralgia patients operated with microvascular decompression: A comparison with multiple sclerosis patients and non-neurological controls
- Download full text (pdf) of Exploring biomarkers in trigeminal neuralgia patients operated with microvascular decompression: A comparison with multiple sclerosis patients and non-neurological controls
Part of Translational Psychiatry, 2024
- DOI for Decoding depression: a comprehensive multi-cohort exploration of blood DNA methylation using machine learning and deep learning approaches
- Download full text (pdf) of Decoding depression: a comprehensive multi-cohort exploration of blood DNA methylation using machine learning and deep learning approaches
Part of EBioMedicine, 2024
- DOI for Identifying proteomic risk factors for overall, aggressive, and early onset prostate cancer using Mendelian Randomisation and tumour spatial transcriptomics
- Download full text (pdf) of Identifying proteomic risk factors for overall, aggressive, and early onset prostate cancer using Mendelian Randomisation and tumour spatial transcriptomics
Identifying therapeutic targets for cancer among 2074 circulating proteins and risk of nine cancers
Part of Nature Communications, 2024
- DOI for Identifying therapeutic targets for cancer among 2074 circulating proteins and risk of nine cancers
- Download full text (pdf) of Identifying therapeutic targets for cancer among 2074 circulating proteins and risk of nine cancers
Part of Clinical Epigenetics, 2023
- DOI for Methylation in MAD1L1 is associated with the severity of suicide attempt and phenotypes of depression
- Download full text (pdf) of Methylation in MAD1L1 is associated with the severity of suicide attempt and phenotypes of depression
Part of Frontiers in Pharmacology, 2023
- DOI for The international clinical trials registry platform (ICTRP): data integrity and the trends in clinical trials, diseases, and drugs
- Download full text (pdf) of The international clinical trials registry platform (ICTRP): data integrity and the trends in clinical trials, diseases, and drugs
Evaluation of circulating plasma proteins in breast cancer using Mendelian randomisation
Part of Nature Communications, 2023
- DOI for Evaluation of circulating plasma proteins in breast cancer using Mendelian randomisation
- Download full text (pdf) of Evaluation of circulating plasma proteins in breast cancer using Mendelian randomisation
Trends in kinase drug discovery: targets, indications and inhibitor design
Part of Nature reviews. Drug discovery, p. 839-861, 2021
Articles, review/survey
Part of Translational Psychiatry, 2024
- DOI for Depression clinical trials worldwide: a systematic analysis of the ICTRP and comparison with ClinicalTrials.gov
- Download full text (pdf) of Depression clinical trials worldwide: a systematic analysis of the ICTRP and comparison with ClinicalTrials.gov
Part of International Journal of Molecular Sciences, 2023
- DOI for Nanoparticles in Clinical Trials: Analysis of Clinical Trials, FDA Approvals and Use for COVID-19 Vaccines
- Download full text (pdf) of Nanoparticles in Clinical Trials: Analysis of Clinical Trials, FDA Approvals and Use for COVID-19 Vaccines
Part of Frontiers in Pharmacology, 2022
- DOI for Treatment of ADHD: Drugs, psychological therapies, devices, complementary and alternative methods as well as the trends in clinical trials
- Download full text (pdf) of Treatment of ADHD: Drugs, psychological therapies, devices, complementary and alternative methods as well as the trends in clinical trials
Neoantigen Vaccines; Clinical Trials, Classes, Indications, Adjuvants and Combinatorial Treatments
Part of Cancers, 2022
- DOI for Neoantigen Vaccines; Clinical Trials, Classes, Indications, Adjuvants and Combinatorial Treatments
- Download full text (pdf) of Neoantigen Vaccines; Clinical Trials, Classes, Indications, Adjuvants and Combinatorial Treatments
Brain Cancer Drug Discovery: Clinical Trials, Drug Classes, Targets, and Combinatorial Therapies
Part of Pharmacological Reviews, p. 1-32, 2021
- DOI for Brain Cancer Drug Discovery: Clinical Trials, Drug Classes, Targets, and Combinatorial Therapies
- Download full text (pdf) of Brain Cancer Drug Discovery: Clinical Trials, Drug Classes, Targets, and Combinatorial Therapies