Aleksandr Sokolov

Trends in kinase drug discovery: targets, indications and inhibitor design

Attwood, Misty M.; Fabbro, Doriano; Sokolov, Aleksandr V.; Knapp, Stefan et al.

Ingår i Nature reviews. Drug discovery, s. 839-861, 2021

• DOI för Trends in kinase drug discovery: targets, indications and inhibitor design

Brain Cancer Drug Discovery: Clinical Trials, Drug Classes, Targets, and Combinatorial Therapies

Sokolov, Aleksandr V.; Dostdar, Samira A.; Attwood, Misty M.; Krasilnikova, Aleksandra A. et al.

Ingår i Pharmacological Reviews, s. 1-32, 2021

• DOI för Brain Cancer Drug Discovery: Clinical Trials, Drug Classes, Targets, and Combinatorial Therapies
• Ladda ner fulltext (pdf) av Brain Cancer Drug Discovery: Clinical Trials, Drug Classes, Targets, and Combinatorial Therapies

GPCR drug discovery: new agents, targets and indications

Lorente, Javier Sánchez; Sokolov, Aleksandr V.; Ferguson, Gavin; Schiöth, Helgi et al.

Ingår i Nature reviews. Drug discovery, 2025

• DOI för GPCR drug discovery: new agents, targets and indications

LEAP2 is associated with impulsivity and reward sensitivity depending on the nutritional status and decreases with protein intake in humans

Andreoli, María Florencia; Kruger, Ana Luz; Sokolov, Aleksandr V.; Rukh, Gull et al.

Ingår i Diabetes, obesity and metabolism, s. 4734-4743, 2024

• DOI för LEAP2 is associated with impulsivity and reward sensitivity depending on the nutritional status and decreases with protein intake in humans
• Ladda ner fulltext (pdf) av LEAP2 is associated with impulsivity and reward sensitivity depending on the nutritional status and decreases with protein intake in humans

Genomic Validation in the UK Biobank Cohort Suggests a Role of C8B and MFG-E8 in the Pathogenesis of Trigeminal Neuralgia

Lafta, Muataz S.; Rukh, Gull; Abu Hamdeh, Sami; Molero, Yasmina et al.

Ingår i Journal of Molecular Neuroscience, 2024

• DOI för Genomic Validation in the UK Biobank Cohort Suggests a Role of C8B and MFG-E8 in the Pathogenesis of Trigeminal Neuralgia
• Ladda ner fulltext (pdf) av Genomic Validation in the UK Biobank Cohort Suggests a Role of C8B and MFG-E8 in the Pathogenesis of Trigeminal Neuralgia

Depression clinical trials worldwide: a systematic analysis of the ICTRP and comparison with ClinicalTrials.gov

Namiot, Eugenia; Smirnovová, Diana; Sokolov, Aleksandr V.; Chubarev, Vladimir N. et al.

Ingår i Translational Psychiatry, 2024

• DOI för Depression clinical trials worldwide: a systematic analysis of the ICTRP and comparison with ClinicalTrials.gov
• Ladda ner fulltext (pdf) av Depression clinical trials worldwide: a systematic analysis of the ICTRP and comparison with ClinicalTrials.gov

Depression proteomic profiling in adolescents with transcriptome analyses in independent cohorts

Sokolov, Aleksandr V.; Lafta, Muataz; Nordberg, Didi; Jonsson, Jörgen et al.

Ingår i Frontiers in Psychiatry, 2024

• DOI för Depression proteomic profiling in adolescents with transcriptome analyses in independent cohorts
• Ladda ner fulltext (pdf) av Depression proteomic profiling in adolescents with transcriptome analyses in independent cohorts

GPCR drug discovery: new agents, targets and indications

Lorente, Javier Sánchez; Sokolov, Aleksandr V.; Ferguson, Gavin; Schiöth, Helgi et al.

Ingår i Nature reviews. Drug discovery, 2025

• DOI för GPCR drug discovery: new agents, targets and indications

LEAP2 is associated with impulsivity and reward sensitivity depending on the nutritional status and decreases with protein intake in humans

Andreoli, María Florencia; Kruger, Ana Luz; Sokolov, Aleksandr V.; Rukh, Gull et al.

Ingår i Diabetes, obesity and metabolism, s. 4734-4743, 2024

• DOI för LEAP2 is associated with impulsivity and reward sensitivity depending on the nutritional status and decreases with protein intake in humans
• Ladda ner fulltext (pdf) av LEAP2 is associated with impulsivity and reward sensitivity depending on the nutritional status and decreases with protein intake in humans

Genomic Validation in the UK Biobank Cohort Suggests a Role of C8B and MFG-E8 in the Pathogenesis of Trigeminal Neuralgia

Lafta, Muataz S.; Rukh, Gull; Abu Hamdeh, Sami; Molero, Yasmina et al.

Ingår i Journal of Molecular Neuroscience, 2024

• DOI för Genomic Validation in the UK Biobank Cohort Suggests a Role of C8B and MFG-E8 in the Pathogenesis of Trigeminal Neuralgia
• Ladda ner fulltext (pdf) av Genomic Validation in the UK Biobank Cohort Suggests a Role of C8B and MFG-E8 in the Pathogenesis of Trigeminal Neuralgia

Depression proteomic profiling in adolescents with transcriptome analyses in independent cohorts

Sokolov, Aleksandr V.; Lafta, Muataz; Nordberg, Didi; Jonsson, Jörgen et al.

Ingår i Frontiers in Psychiatry, 2024

• DOI för Depression proteomic profiling in adolescents with transcriptome analyses in independent cohorts
• Ladda ner fulltext (pdf) av Depression proteomic profiling in adolescents with transcriptome analyses in independent cohorts

Exploring biomarkers in trigeminal neuralgia patients operated with microvascular decompression: A comparison with multiple sclerosis patients and non-neurological controls

Lafta, Muataz S; Sokolov, Aleksandr V.; Landtblom, Anne-Marie; Ericson, Hans et al.

Ingår i European Journal of Pain, s. 929-942, 2024

• DOI för Exploring biomarkers in trigeminal neuralgia patients operated with microvascular decompression: A comparison with multiple sclerosis patients and non-neurological controls
• Ladda ner fulltext (pdf) av Exploring biomarkers in trigeminal neuralgia patients operated with microvascular decompression: A comparison with multiple sclerosis patients and non-neurological controls

Decoding depression: a comprehensive multi-cohort exploration of blood DNA methylation using machine learning and deep learning approaches

Sokolov, Aleksandr V.; Schiöth, Helgi

Ingår i Translational Psychiatry, 2024

• DOI för Decoding depression: a comprehensive multi-cohort exploration of blood DNA methylation using machine learning and deep learning approaches
• Ladda ner fulltext (pdf) av Decoding depression: a comprehensive multi-cohort exploration of blood DNA methylation using machine learning and deep learning approaches

Identifying proteomic risk factors for overall, aggressive, and early onset prostate cancer using Mendelian Randomisation and tumour spatial transcriptomics

Desai, Trishna A.; Hedman, Asa K.; Dimitriou, Marios; Koprulu, Mine et al.

Ingår i EBioMedicine, 2024

• DOI för Identifying proteomic risk factors for overall, aggressive, and early onset prostate cancer using Mendelian Randomisation and tumour spatial transcriptomics
• Ladda ner fulltext (pdf) av Identifying proteomic risk factors for overall, aggressive, and early onset prostate cancer using Mendelian Randomisation and tumour spatial transcriptomics

Identifying therapeutic targets for cancer among 2074 circulating proteins and risk of nine cancers

Smith-Byrne, Karl; Hedman, Åsa; Dimitriou, Marios; Desai, Trishna et al.

Ingår i Nature Communications, 2024

• DOI för Identifying therapeutic targets for cancer among 2074 circulating proteins and risk of nine cancers
• Ladda ner fulltext (pdf) av Identifying therapeutic targets for cancer among 2074 circulating proteins and risk of nine cancers

Methylation in MAD1L1 is associated with the severity of suicide attempt and phenotypes of depression

Sokolov, Aleksandr V.; Manu, Diana-Maria; Nordberg, Didi O. T.; Boström, Adrian D. E. et al.

Ingår i Clinical Epigenetics, 2023

• DOI för Methylation in MAD1L1 is associated with the severity of suicide attempt and phenotypes of depression
• Ladda ner fulltext (pdf) av Methylation in MAD1L1 is associated with the severity of suicide attempt and phenotypes of depression

The international clinical trials registry platform (ICTRP): data integrity and the trends in clinical trials, diseases, and drugs

Namiot, Eugenia D.; Smirnovová, Diana; Sokolov, Aleksandr V.; Chubarev, Vladimir N. et al.

Ingår i Frontiers in Pharmacology, 2023

• DOI för The international clinical trials registry platform (ICTRP): data integrity and the trends in clinical trials, diseases, and drugs
• Ladda ner fulltext (pdf) av The international clinical trials registry platform (ICTRP): data integrity and the trends in clinical trials, diseases, and drugs

Evaluation of circulating plasma proteins in breast cancer using Mendelian randomisation

Mälarstig, Anders; Grassmann, Felix; Dahl, Leo; Dimitriou, Marios et al.

Ingår i Nature Communications, 2023

• DOI för Evaluation of circulating plasma proteins in breast cancer using Mendelian randomisation
• Ladda ner fulltext (pdf) av Evaluation of circulating plasma proteins in breast cancer using Mendelian randomisation

Trends in kinase drug discovery: targets, indications and inhibitor design

Attwood, Misty M.; Fabbro, Doriano; Sokolov, Aleksandr V.; Knapp, Stefan et al.

Ingår i Nature reviews. Drug discovery, s. 839-861, 2021

• DOI för Trends in kinase drug discovery: targets, indications and inhibitor design

Depression clinical trials worldwide: a systematic analysis of the ICTRP and comparison with ClinicalTrials.gov

Namiot, Eugenia; Smirnovová, Diana; Sokolov, Aleksandr V.; Chubarev, Vladimir N. et al.

Ingår i Translational Psychiatry, 2024

• DOI för Depression clinical trials worldwide: a systematic analysis of the ICTRP and comparison with ClinicalTrials.gov
• Ladda ner fulltext (pdf) av Depression clinical trials worldwide: a systematic analysis of the ICTRP and comparison with ClinicalTrials.gov

Nanoparticles in Clinical Trials: Analysis of Clinical Trials, FDA Approvals and Use for COVID-19 Vaccines

Namiot, Eugenia D.; Sokolov, Aleksandr V.; Chubarev, Vladimir N.; Tarasov, Vadim V. et al.

Ingår i International Journal of Molecular Sciences, 2023

• DOI för Nanoparticles in Clinical Trials: Analysis of Clinical Trials, FDA Approvals and Use for COVID-19 Vaccines
• Ladda ner fulltext (pdf) av Nanoparticles in Clinical Trials: Analysis of Clinical Trials, FDA Approvals and Use for COVID-19 Vaccines

Treatment of ADHD: Drugs, psychological therapies, devices, complementary and alternative methods as well as the trends in clinical trials

Nazarova, Victoria A.; Sokolov, Aleksandr V.; Chubarev, Vladimir N.; Tarasov, Vadim V. et al.

Ingår i Frontiers in Pharmacology, 2022

• DOI för Treatment of ADHD: Drugs, psychological therapies, devices, complementary and alternative methods as well as the trends in clinical trials
• Ladda ner fulltext (pdf) av Treatment of ADHD: Drugs, psychological therapies, devices, complementary and alternative methods as well as the trends in clinical trials

Neoantigen Vaccines; Clinical Trials, Classes, Indications, Adjuvants and Combinatorial Treatments

Niemi, Jenni Viivi Linnea; Sokolov, Aleksandr V.; Schiöth, Helgi B.

Ingår i Cancers, 2022

• DOI för Neoantigen Vaccines; Clinical Trials, Classes, Indications, Adjuvants and Combinatorial Treatments
• Ladda ner fulltext (pdf) av Neoantigen Vaccines; Clinical Trials, Classes, Indications, Adjuvants and Combinatorial Treatments

Brain Cancer Drug Discovery: Clinical Trials, Drug Classes, Targets, and Combinatorial Therapies

Sokolov, Aleksandr V.; Dostdar, Samira A.; Attwood, Misty M.; Krasilnikova, Aleksandra A. et al.

Ingår i Pharmacological Reviews, s. 1-32, 2021

• DOI för Brain Cancer Drug Discovery: Clinical Trials, Drug Classes, Targets, and Combinatorial Therapies
• Ladda ner fulltext (pdf) av Brain Cancer Drug Discovery: Clinical Trials, Drug Classes, Targets, and Combinatorial Therapies

Biomarkers for depression: genetic, epigenetic, and expression evidence

Sokolov, Aleksandr V.

2024

• Ladda ner fulltext (pdf) av Biomarkers for depression: genetic, epigenetic, and expression evidence

Cross-omics cross-cohort analysis indicates multiple biological systemsimplicated in depression

Sokolov, Aleksandr V.; Knauer-Arloth, Janine; Schiöth, Helgi

Exploratory Assessment of Candidate Biomarkers in Narcolepsy: Identification and Validation in H1N1-Vaccinated Cohorts at the Proteome and Transcriptome Levels

Lafta, Muataz S.; Sokolov, Aleksandr V.; Mattis, Kitok; Berntsson, Shala et al.

Identification and validation of depression-associated genetic variants in the UK Biobank cohort with transcriptome and DNA methylation analyses in independent cohorts

Lafta, Muataz; Sokolov, Aleksandr V.; Rukh, Gull; Schiöth, Helgi