Erik Holmqvist

An RNA structural switch controlling bacterial toxin translation

Eleftheraki, Athina; Escalera-Maurer, Andrés; Hien, Elsa D. M.; Virciglio, Alice et al.

Part of Nucleic Acids Research, 2026

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The pcnB gene sustains Shigella flexneri virulence

Frisch, Thibault; Geiser, Petra; Komi, Margarita; Karlsson, Philip A. et al.

Part of PLoS Pathogens, 2025

• DOI for The pcnB gene sustains Shigella flexneri virulence

ProQ prevents mRNA degradation through inhibition of poly(A) polymerase

Bergman, Sofia; Birk, Christopher; Holmqvist, Erik

Part of Nucleic Acids Research, 2025

• DOI for ProQ prevents mRNA degradation through inhibition of poly(A) polymerase
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Global Identification of RNA-Binding Proteins in Bacteria

Stenum, Thomas Søndergaard; Holmqvist, Erik

Part of Bacterial Regulatory RNA, p. 347-361, Springer Nature, 2024

• DOI for Global Identification of RNA-Binding Proteins in Bacteria

An RNA pseudoknot mediates toxin translation and antitoxin inhibition

Eleftheraki, Athina; Holmqvist, Erik

Part of Proceedings of the National Academy of Sciences of the United States of America, 2024

• DOI for An RNA pseudoknot mediates toxin translation and antitoxin inhibition
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An RNA structural switch controlling bacterial toxin translation

Eleftheraki, Athina; Escalera-Maurer, Andrés; Hien, Elsa D. M.; Virciglio, Alice et al.

Part of Nucleic Acids Research, 2026

• DOI for An RNA structural switch controlling bacterial toxin translation
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The pcnB gene sustains Shigella flexneri virulence

Frisch, Thibault; Geiser, Petra; Komi, Margarita; Karlsson, Philip A. et al.

Part of PLoS Pathogens, 2025

• DOI for The pcnB gene sustains Shigella flexneri virulence

ProQ prevents mRNA degradation through inhibition of poly(A) polymerase

Bergman, Sofia; Birk, Christopher; Holmqvist, Erik

Part of Nucleic Acids Research, 2025

• DOI for ProQ prevents mRNA degradation through inhibition of poly(A) polymerase
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An RNA pseudoknot mediates toxin translation and antitoxin inhibition

Eleftheraki, Athina; Holmqvist, Erik

Part of Proceedings of the National Academy of Sciences of the United States of America, 2024

• DOI for An RNA pseudoknot mediates toxin translation and antitoxin inhibition
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ProQ-dependent activation of Salmonella virulence genes mediated by post-transcriptional control of PhoP synthesis

Bergman, Sofia; Andresen, Liis; Kjellin, Jonas; Burgo, Yolanda Martinez et al.

Part of mSphere, 2024

• DOI for ProQ-dependent activation of Salmonella virulence genes mediated by post-transcriptional control of PhoP synthesis
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Rescue of Escherichia coli auxotrophy by de novo small proteins

Babina, Arianne M.; Surkov, Serhiy; Ye, Weihua; Jerlström-Hultqvist, Jon et al.

Part of eLIFE, 2023

• DOI for Rescue of Escherichia coli auxotrophy by de novo small proteins
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RNA interactome capture in Escherichia coli globally identifies RNA-binding proteins

Stenum, Thomas Søndergaard; Kumar, Ankith D.; Sandbaumhueter, Friederike A.; Kjellin, Jonas et al.

Part of Nucleic Acids Research, p. 4572-4587, 2023

• DOI for RNA interactome capture in Escherichia coli globally identifies RNA-binding proteins
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CsrA enters Hfq's territory: Regulation of a base-pairing small RNA

Søndergaard Stenum, Thomas; Holmqvist, Erik

Part of Molecular Microbiology, p. 4-9, 2022

• DOI for CsrA enters Hfq's territory: Regulation of a base-pairing small RNA
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The RNA-binding protein ProQ promotes antibiotic persistence in Salmonella

Rizvanovic, Alisa; Michaux, Charlotte; Panza, Margherita; Iloglu, Zeynep et al.

Part of Molecular and Cellular Biology, 2022

• DOI for The RNA-binding protein ProQ promotes antibiotic persistence in Salmonella
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Three Ribosomal Operons of Escherichia coli Contain Genes Encoding Small RNAs That Interact With Hfq and CsrA in vitro

Stenum, Thomas Søndergaard; Kongstad, Mette; Holmqvist, Erik; Kallipolitis, Birgitte et al.

Part of Frontiers in Microbiology, 2021

• DOI for Three Ribosomal Operons of Escherichia coli Contain Genes Encoding Small RNAs That Interact With Hfq and CsrA in vitro

Saturation mutagenesis charts the functional landscape of Salmonella ProQ and reveals a gene regulatory function of its C-terminal domain

Rizvanovic, Alisa; Kjellin, Jonas; Söderbom, Fredrik; Holmqvist, Erik

Part of Nucleic Acids Research, p. 9992-10006, 2021

• DOI for Saturation mutagenesis charts the functional landscape of Salmonella ProQ and reveals a gene regulatory function of its C-terminal domain
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The Small Toxic Salmonella Protein TimP Targets the Cytoplasmic Membrane and Is Repressed by the Small RNA TimR

Andresen, Liis; Martinez-Burgo, Yolanda; Nilsson Zangelin, Josefin; Rizvanovic, Alisa et al.

Part of mBio, 2020

• DOI for The Small Toxic Salmonella Protein TimP Targets the Cytoplasmic Membrane and Is Repressed by the Small RNA TimR
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Small RNAs OmrA and OmrB promote class III flagellar gene expression by inhibiting the synthesis of anti-Sigma factor FlgM

Romilly, Cedric; Hoekzema, Mirthe; Holmqvist, Erik; Wagner, Gerhart E. H.

Part of RNA Biology, p. 872-880, 2020

• DOI for Small RNAs OmrA and OmrB promote class III flagellar gene expression by inhibiting the synthesis of anti-Sigma factor FlgM
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The Length of a DNA T-Tract Modulates Expression of a Virulence-Regulating sRNA

Wagner, E. Gerhart H.; Holmqvist, Erik

Part of Molecular Cell, p. 175-177, 2020

• DOI for The Length of a DNA T-Tract Modulates Expression of a Virulence-Regulating sRNA

Hfq-dependent mRNA unfolding promotes sRNA-based inhibition of translation

Hoekzema, Mirthe; Romilly, Cedric; Holmqvist, Erik; Wagner, Gerhart E. H.

Part of EMBO Journal, 2019

• DOI for Hfq-dependent mRNA unfolding promotes sRNA-based inhibition of translation
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Global Maps of ProQ Binding In Vivo Reveal Target Recognition via RNA Structure and Stability Control at mRNA 3 ' Ends

Holmqvist, Erik; Li, Lei; Bischler, Thorsten; Barquist, Lars et al.

Part of Molecular Cell, p. 971-982, 2018

• DOI for Global Maps of ProQ Binding In Vivo Reveal Target Recognition via RNA Structure and Stability Control at mRNA 3 ' Ends

Structure of the Escherichia coli ProQ RNA-binding protein

Gonzalez, Grecia M.; Hardwick, Steven W.; Maslen, Sarah L.; Skehel, J. Mark et al.

Part of RNA, p. 696-711, 2017

• DOI for Structure of the Escherichia coli ProQ RNA-binding protein
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Massive functional mapping of a 5'-UTR by saturation mutagenesis, phenotypic sorting and deep sequencing

Holmqvist, Erik; Reimegard, Johan; Wagner, Gerhart E. H.

Part of Nucleic Acids Research, 2013

• DOI for Massive functional mapping of a 5'-UTR by saturation mutagenesis, phenotypic sorting and deep sequencing
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A mixed double negative feedback loop between the sRNA MicF and the global regulator Lrp

Holmqvist, Erik; Unoson, Cecilia; Reimegård, Johan; Wagner, Gerhart E. H.

Part of Molecular Microbiology, p. 414-427, 2012

• DOI for A mixed double negative feedback loop between the sRNA MicF and the global regulator Lrp

Two antisense RNAs target the transcriptional regulator CsgD to inhibit curli synthesis

Holmqvist, Erik; Reimegård, Johan; Sterk, Maaike; Grantcharova, Nina et al.

Part of EMBO Journal, p. 1840-1850, 2010

• DOI for Two antisense RNAs target the transcriptional regulator CsgD to inhibit curli synthesis

Sensory ataxic neuropathy in golden retriever dogs is caused by a deletion in the mitochondrial tRNA^Tyr gene

Baranowska, Izabella; Jäderlund, Karin Hultin; Nennesmo, Inger; Holmqvist, Erik et al.

Part of PLoS Genetics, 2009

• DOI for Sensory ataxic neuropathy in golden retriever dogs is caused by a deletion in the mitochondrial tRNA^Tyr gene

Hfq-dependent regulation of OmpA synthesis is mediated by an an-tisense RNA.

Udekwu, Klas I; Darfeuille, Fabien; Vogel, Jörg; Reimegård, Johan et al.

Part of Genes & Development, p. 2355-2366, 2005

• DOI for Hfq-dependent regulation of OmpA synthesis is mediated by an an-tisense RNA.

RNA-binding activity and regulatory functions of the emerging sRNA-binding protein ProQ

Holmqvist, Erik; Berggren, Sofia; Rizvanovic, Alisa

Part of Biochimica et Biophysica Acta. Gene Regulatory Mechanisms, 2020

• DOI for RNA-binding activity and regulatory functions of the emerging sRNA-binding protein ProQ

RNA-binding proteins in bacteria

Holmqvist, Erik; Vogel, Jörg

Part of Nature Reviews Microbiology, p. 601-615, 2018

• DOI for RNA-binding proteins in bacteria

Impact of bacterial sRNAs in stress responses

Holmqvist, Erik; Wagner, E. Gerhart H.

Part of Biochemical Society Transactions, p. 1203-1212, 2017

• DOI for Impact of bacterial sRNAs in stress responses
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Global Identification of RNA-Binding Proteins in Bacteria

Stenum, Thomas Søndergaard; Holmqvist, Erik

Part of Bacterial Regulatory RNA, p. 347-361, Springer Nature, 2024

• DOI for Global Identification of RNA-Binding Proteins in Bacteria

CLIP-Seq in Bacteria: Global Recognition Patterns of Bacterial RNA-Binding Proteins

Andresen, Liis; Holmqvist, Erik

Part of High-Density Sequencing Applications in Microbial Molecular Genetics, p. 127-145, ELSEVIER ACADEMIC PRESS INC, 2018

• DOI for CLIP-Seq in Bacteria: Global Recognition Patterns of Bacterial RNA-Binding Proteins

Macromolecular Matchmaking: Mechanisms and Biology of Bacterial Small RNAs

Holmqvist, Erik

2012

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The sRNA MicF targets its own regulator Lrp and promotes a positive feedback loop

Holmqvist, Erik; Unoson, Cecilia; Reimegård, Johan; Wagner, Gerhart E. H.