David Fange

LacI strikes a balance between stability and inducibility

Yuan, Jinwen; Lüking, Malin; Zikrin, Spartak; Sen, Beer Chakra et al.

Part of Nucleic Acids Research, 2026

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Pooled optical screening in bacteria using chromosomally expressed barcodes

Soares, Ruben R. G.; Garcia-Soriano, Daniela A.; Larsson, Jimmy; Fange, David et al.

Part of Communications Biology, 2025

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The Escherichia coli chromosome moves to the replisome

Gras, Konrad; Fange, David; Elf, Johan

Part of Nature Communications, 2024

• DOI for The Escherichia coli chromosome moves to the replisome
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Regulatory elements coordinating initiation of chromosome replication to the Escherichia coli cell cycle

Knöppel, Anna; Broström, Oscar; Gras, Konrad; Elf, Johan et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, 2023

• DOI for Regulatory elements coordinating initiation of chromosome replication to the Escherichia coli cell cycle
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Time-resolved imaging-based CRISPRi screening

Camsund, Daniel; Lawson, Michael J.; Larsson, Jimmy; Jones, Daniel et al.

Part of Nature Methods, p. 86-92, 2020

• DOI for Time-resolved imaging-based CRISPRi screening

LacI strikes a balance between stability and inducibility

Yuan, Jinwen; Lüking, Malin; Zikrin, Spartak; Sen, Beer Chakra et al.

Part of Nucleic Acids Research, 2026

• DOI for LacI strikes a balance between stability and inducibility
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Pooled optical screening in bacteria using chromosomally expressed barcodes

Soares, Ruben R. G.; Garcia-Soriano, Daniela A.; Larsson, Jimmy; Fange, David et al.

Part of Communications Biology, 2025

• DOI for Pooled optical screening in bacteria using chromosomally expressed barcodes
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The Escherichia coli chromosome moves to the replisome

Gras, Konrad; Fange, David; Elf, Johan

Part of Nature Communications, 2024

• DOI for The Escherichia coli chromosome moves to the replisome
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Regulatory elements coordinating initiation of chromosome replication to the Escherichia coli cell cycle

Knöppel, Anna; Broström, Oscar; Gras, Konrad; Elf, Johan et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, 2023

• DOI for Regulatory elements coordinating initiation of chromosome replication to the Escherichia coli cell cycle
• Download full text (pdf) of Regulatory elements coordinating initiation of chromosome replication to the Escherichia coli cell cycle

Time-resolved imaging-based CRISPRi screening

Camsund, Daniel; Lawson, Michael J.; Larsson, Jimmy; Jones, Daniel et al.

Part of Nature Methods, p. 86-92, 2020

• DOI for Time-resolved imaging-based CRISPRi screening

In situ genotyping of a pooled strain library after characterizing complex phenotypes

Lawson, Michael J.; Camsund, Daniel; Larsson, Jimmy; Baltekin, Özden et al.

Part of Molecular Systems Biology, 2017

• DOI for In situ genotyping of a pooled strain library after characterizing complex phenotypes
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Kinetics of dCas9 target search in Escherichia coli

Jones, Daniel; Leroy, Prune; Unoson, Cecilia; Fange, David et al.

Part of Science, p. 1420-1423, 2017

• DOI for Kinetics of dCas9 target search in Escherichia coli

Simulated single molecule microscopy with SMeagol

Lindén, Martin; Ćurić, Vladimir; Boucharin, Alexis; Fange, David et al.

Part of Bioinformatics, p. 2394-2395, 2016

• DOI for Simulated single molecule microscopy with SMeagol
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The Synchronization of Replication and Division Cycles in Individual E. coli Cells

Walldén, Mats; Fange, David; Lundius, Ebba Gregorsson; Baltekin, Özden et al.

Part of Cell, p. 729-739, 2016

• DOI for The Synchronization of Replication and Division Cycles in Individual E. coli Cells

Single-particle tracking reveals that free ribosomal subunits are not excluded from the Escherichia coli nucleoid

Sanamrad, Arash; Persson, Fredrik; Lundius, Ebba G.; Fange, David et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 11413-11418, 2014

• DOI for Single-particle tracking reveals that free ribosomal subunits are not excluded from the Escherichia coli nucleoid

Direct measurement of transcription factor dissociation excludes a simple operator occupancy model for gene regulation

Hammar, Petter; Walldén, Mats; Fange, David; Persson, Fredrik et al.

Part of Nature Genetics, p. 405-+, 2014

• DOI for Direct measurement of transcription factor dissociation excludes a simple operator occupancy model for gene regulation

Thermodynamic Modeling of Variations in the Rate of RNA Chain Elongation of E-coli rrn Operons

Fange, David; Mellenius, Harriet; Dennis, Patrick P.; Ehrenberg, Måns

Part of Biophysical Journal, p. 55-64, 2014

• DOI for Thermodynamic Modeling of Variations in the Rate of RNA Chain Elongation of E-coli rrn Operons

Transcription-factor binding and sliding on DNA studied using micro- and macroscopic models

Marklund, Erik G.; Mahmutovic, Anel; Berg, Otto G.; Hammar, Petter et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 19796-19801, 2013

• DOI for Transcription-factor binding and sliding on DNA studied using micro- and macroscopic models

Lost in presumption: stochastic reactions in spatial models

Mahmutovic, Anel; Fange, David; Berg, Otto G.; Elf, Johan

Part of Nature Methods, p. 1163-1166, 2012

• DOI for Lost in presumption: stochastic reactions in spatial models

MesoRD 1.0: Stochastic reaction-diffusion simulations in the microscopic limit

Fange, David; Mahmutovic, Anel; Elf, Johan

Part of Bioinformatics, p. 3155-3157, 2012

• DOI for MesoRD 1.0: Stochastic reaction-diffusion simulations in the microscopic limit

Stochastic reaction-diffusion kinetics in the microscopic limit

Fange, David; Berg, Otto G; Sjöberg, Paul; Elf, Johan

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 19820-19825, 2010

• DOI for Stochastic reaction-diffusion kinetics in the microscopic limit

Drug efflux pump deficiency and drug target resistance masking in growing bacteria

Fange, David; Nilsson, Karin; Tenson, Tanel; Ehrenberg, Måns

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 8215-8220, 2009

• DOI for Drug efflux pump deficiency and drug target resistance masking in growing bacteria

Noise-induced Min phenotypes in E. coli

Fange, David; Elf, Johan

Part of PloS Computational Biology, p. 637-648, 2006

• DOI for Noise-induced Min phenotypes in E. coli

Modelling Approaches to Molecular Systems Biology

Fange, David

2010

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Fluctuations in replication initiation determine the generation time and size distributions of E. coli cells

Walldén, Mats; Fange, David; Gustaf, Ullman; Marklund, Erik G et al.

Transcription factor dissociation measurements using single molecule chase in living cells

Hammar, Petter; Walldén, Mats; Fange, David; Baltekin, Özden et al.

Molecular Origins of Kinetics and Selectivity in the lac operon

Lüking, Malin; Yuan, Jinwen; Larsson, Jimmy; Fange, David et al.

The LacI hinge region balances binding stability against inducibility

Yuan, Jinwen; Lüking, Malin; Zikrin, Spartak; Sen, Beer Chakra et al.

• DOI for The LacI hinge region balances binding stability against inducibility