Patrick Micke

Incremental prognostic value of immune cell densities beyond clinical parameters in non-small cell lung cancer

Nordling, Love; Backman, Max; Mezheyeuski, Artur; Lindblad, Joakim et al.

Part of Lung Cancer, 2026

• DOI for Incremental prognostic value of immune cell densities beyond clinical parameters in non-small cell lung cancer
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In situ mapping of activated PDGFRβ defines a prognostic discrepancy between histological subtypes of NSCLC

Lindberg, Amanda; Hellberg, Louise; Grandon, Anaïs; Yu, Hui et al.

Part of Cell Communication and Signaling, 2026

• DOI for In situ mapping of activated PDGFRβ defines a prognostic discrepancy between histological subtypes of NSCLC
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Isolated Channel Vision Transformers: From Single-Channel Pretraining to Multi-Channel Finetuning

Lian, Wenyi; Micke, Patrick; Lindblad, Joakim; Sladoje, Nataša

Part of 36th British Machine Vision Conference 2025, {BMVC} 2025, p. 1-14, 2025

Spatial TCR clonality and clonal expansion in the in situ microenvironment of non-small cell lung cancer

Yu, Hui; Magoulopoulou, Anastasia; Amini, Rose-Marie; Chatzinikolaou, Maria Paraskevi et al.

Part of Journal for ImmunoTherapy of Cancer, 2025

• DOI for Spatial TCR clonality and clonal expansion in the in situ microenvironment of non-small cell lung cancer
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In situ detection of PD1–PD-L1 interactions as a functional predictor for response to immune checkpoint inhibition in NSCLC

Lindberg, Amanda; Muhl, Lars; Yu, Hui; Hellberg, Louise et al.

Part of Journal of Thoracic Oncology, p. 625-640, 2025

• DOI for In situ detection of PD1–PD-L1 interactions as a functional predictor for response to immune checkpoint inhibition in NSCLC
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Incremental prognostic value of immune cell densities beyond clinical parameters in non-small cell lung cancer

Nordling, Love; Backman, Max; Mezheyeuski, Artur; Lindblad, Joakim et al.

Part of Lung Cancer, 2026

• DOI for Incremental prognostic value of immune cell densities beyond clinical parameters in non-small cell lung cancer
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In situ mapping of activated PDGFRβ defines a prognostic discrepancy between histological subtypes of NSCLC

Lindberg, Amanda; Hellberg, Louise; Grandon, Anaïs; Yu, Hui et al.

Part of Cell Communication and Signaling, 2026

• DOI for In situ mapping of activated PDGFRβ defines a prognostic discrepancy between histological subtypes of NSCLC
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Spatial TCR clonality and clonal expansion in the in situ microenvironment of non-small cell lung cancer

Yu, Hui; Magoulopoulou, Anastasia; Amini, Rose-Marie; Chatzinikolaou, Maria Paraskevi et al.

Part of Journal for ImmunoTherapy of Cancer, 2025

• DOI for Spatial TCR clonality and clonal expansion in the in situ microenvironment of non-small cell lung cancer
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In situ detection of PD1–PD-L1 interactions as a functional predictor for response to immune checkpoint inhibition in NSCLC

Lindberg, Amanda; Muhl, Lars; Yu, Hui; Hellberg, Louise et al.

Part of Journal of Thoracic Oncology, p. 625-640, 2025

• DOI for In situ detection of PD1–PD-L1 interactions as a functional predictor for response to immune checkpoint inhibition in NSCLC
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scFFPE-ATAC enables high-throughput single cell chromatin accessibility profiling in formalin-fixed paraffin-embedded samples

Yadav, Ram Prakash; Xing, Pengwei; Zhao, Miao; Hollander, Peter et al.

Part of Nature Communications, 2025

• DOI for scFFPE-ATAC enables high-throughput single cell chromatin accessibility profiling in formalin-fixed paraffin-embedded samples
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Prospective validation of ORACLE, a clonal expression biomarker associated with survival of patients with lung adenocarcinoma

Biswas, Dhruva; Liu, Yun-Hsin; Herrero, Javier; Wu, Yin et al.

Part of Nature Cancer, p. 86-101, 2025

• DOI for Prospective validation of ORACLE, a clonal expression biomarker associated with survival of patients with lung adenocarcinoma
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The transcription factor LHX2 mediates and enhances oncogenic BMP signaling in medulloblastoma

Ohata, Yae; Ali, Mohamad M.; Tsubakihara, Yutaro; Itoh, Yuka et al.

Part of Cell Death and Differentiation, p. 1915-1929, 2025

• DOI for The transcription factor LHX2 mediates and enhances oncogenic BMP signaling in medulloblastoma
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Unlocking novel T cell-based immunotherapy for hepatocellular carcinoma through neoantigen-driven T cell receptor isolation

Maravelia, Panagiota; Yao, Haidong; Cai, Curtis; Silva, Daniela Nascimento et al.

Part of Gut, p. 1125-1136, 2025

• DOI for Unlocking novel T cell-based immunotherapy for hepatocellular carcinoma through neoantigen-driven T cell receptor isolation
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Tumoral pSMAD2 as a prognostic biomarker in early-stage breast cancer: insights from the randomized SweBCG91RT trial

Tullberg, Axel Stenmark; Thurfjell, Viktoria; Kovacs, Aniko; Micke, Patrick et al.

Part of Breast Cancer Research and Treatment, p. 499-509, 2025

• DOI for Tumoral pSMAD2 as a prognostic biomarker in early-stage breast cancer: insights from the randomized SweBCG91RT trial
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Spatial distribution of tertiary lymphoid structures in the molecular and clinical context of non-small cell lung cancer.

Elfving, Hedvig; Yu, Hui; Kassete Fessehatsio, Kaleab; Brunnström, Hans et al.

Part of Cellular Oncology, p. 801-808, 2025

• DOI for Spatial distribution of tertiary lymphoid structures in the molecular and clinical context of non-small cell lung cancer.
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Predictors of survival and recurrence patterns following definitive chemoradiotherapy in stage III non-small cell lung cancer: a retrospective cohort study

Broström, Erika; Isaksson, Johan; Xanthoulis, Panagiotis; Börjesson, Rebecka et al.

Part of Translational Lung Cancer Research, p. 1972-1985, 2025

• DOI for Predictors of survival and recurrence patterns following definitive chemoradiotherapy in stage III non-small cell lung cancer: a retrospective cohort study
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Gene expression-based identification of prognostic markers in lung adenocarcinoma

Salomonsson, Annette; Ehinger, Daniel; Jonsson, Mats; Botling, Johan et al.

Part of PLOS ONE, 2025

• DOI for Gene expression-based identification of prognostic markers in lung adenocarcinoma
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Diagnostic gastrointestinal markers in primary lung cancer and pulmonary metastases

Malmros, Karina; Lindholm, Andreas; Vidarsdottir, Halla; Jirström, Karin et al.

Part of Virchows Archiv, p. 347-357, 2024

• DOI for Diagnostic gastrointestinal markers in primary lung cancer and pulmonary metastases
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The histological growth patterns in liver metastases from colorectal cancer display differences in lymphoid, myeloid, and mesenchymal cells

Garcia-Vicien, Gemma; Ruiz, Nuria; Micke, Patrick; Ruffinelli, Jose Carlos et al.

Part of MEDCOMM, 2024

• DOI for The histological growth patterns in liver metastases from colorectal cancer display differences in lymphoid, myeloid, and mesenchymal cells
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Use of beta-blockers in patients with ductal carcinoma in situ and risk of invasive breast cancer recurrence: a Swedish retrospective cohort study

Strell, Carina; Smith, Daniel Robert; Valachis, Antonis; Woldeyesus, Hellen et al.

Part of Breast Cancer Research and Treatment, p. 293-299, 2024

• DOI for Use of beta-blockers in patients with ductal carcinoma in situ and risk of invasive breast cancer recurrence: a Swedish retrospective cohort study
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Distinct microRNA Signature and Suppression of ZFP36L1 Define ASCL1-Positive Lung Adenocarcinoma

Enokido, Takayoshi; Horie, Masafumi; Yoshino, Seiko; Suzuki, Hiroshi I. et al.

Part of Molecular Cancer Research, p. 29-40, 2024

• DOI for Distinct microRNA Signature and Suppression of ZFP36L1 Define ASCL1-Positive Lung Adenocarcinoma

Tumor Heterogeneity Confounds Lymphocyte Metrics in Diagnostic Lung Cancer Biopsies

Elfving, Hedvig; Thurfjell, Viktoria; Mattsson, Johanna Sofia Margareta; Backman, Max et al.

Part of Archives of Pathology & Laboratory Medicine, 2024

• DOI for Tumor Heterogeneity Confounds Lymphocyte Metrics in Diagnostic Lung Cancer Biopsies
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Phenotypic characterization of spatial immune infiltration niches in non-small cell lung cancer

Gerdtsson, Anna Sandström; Knulst, Mattis; Botling, Johan; Mezheyeuski, Artur et al.

Part of Oncoimmunology, 2023

• DOI for Phenotypic characterization of spatial immune infiltration niches in non-small cell lung cancer
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An immune score reflecting pro- and anti-tumoural balance of tumour microenvironment has major prognostic impact and predicts immunotherapy response in solid cancers

Mezheyeuski, Artur; Backman, Max; Mattsson, Johanna Sofia Margareta; Martin-Bernabe, Alfonso et al.

Part of eBioMedicine, 2023

• DOI for An immune score reflecting pro- and anti-tumoural balance of tumour microenvironment has major prognostic impact and predicts immunotherapy response in solid cancers
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Fibroblast subsets in non-small cell lung cancer: Associations with survival, mutations, and immune features

Pellinen, Teijo; Paavolainen, Lassi; Martín-Bernabé, Alfonso; Papatella Araujo, Renata et al.

Part of Journal of the National Cancer Institute, p. 71-82, 2023

• DOI for Fibroblast subsets in non-small cell lung cancer: Associations with survival, mutations, and immune features
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Expression of cancer-testis antigens in the immune microenvironment of non-small cell lung cancer

Hikmet Noraddin, Feria; Rassy, Marc; Backman, Max; Méar, Loren et al.

Part of Molecular Oncology, p. 2603-2617, 2023

• DOI for Expression of cancer-testis antigens in the immune microenvironment of non-small cell lung cancer
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Spatial immunophenotyping of the tumour microenvironment in non-small cell lung cancer

Backman, Max; Strell, Carina; Lindberg, Amanda; Mattsson, Johanna S. M. et al.

Part of European Journal of Cancer, p. 40-52, 2023

• DOI for Spatial immunophenotyping of the tumour microenvironment in non-small cell lung cancer
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Matched Analyses of Brain Metastases versus Primary Non-Small Cell Lung Cancer Reveal a Unique microRNA Signature

Tsakonas, Georgios; Koulouris, Andreas; Kazmierczak, Dominika; Botling, Johan et al.

Part of International Journal of Molecular Sciences, 2023

• DOI for Matched Analyses of Brain Metastases versus Primary Non-Small Cell Lung Cancer Reveal a Unique microRNA Signature
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A Novel Pancreatic Cancer Mini-tumor Model to Study Desmoplasia and Myofibroblastic Cancer-Associated Fibroblast Differentiation

Harryvan, T.J.; Hawinkels, L.J.A.C.; Inderson, A.; van Hooft, J.E. et al.

Part of Gastro Hep Advances, p. 678-681, 2022

• DOI for A Novel Pancreatic Cancer Mini-tumor Model to Study Desmoplasia and Myofibroblastic Cancer-Associated Fibroblast Differentiation
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Comparison of ROS1-rearrangement detection methods in a cohort of surgically resected non-small cell lung carcinomas

Thurfjell, Viktoria; Micke, Patrick; Yu, Hui; Krupar, Rosemarie et al.

Part of Translational Lung Cancer Research, p. 2477-2494, 2022

• DOI for Comparison of ROS1-rearrangement detection methods in a cohort of surgically resected non-small cell lung carcinomas
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Highly elevated systemic inflammation is a strong independent predictor of early mortality in advanced non-small cell lung cancer

Isaksson, Johan; Wennström, Leo; Brandén, Eva; Koyi, Hirsh et al.

Part of Cancer Treatment and Research Communications, 2022

• DOI for Highly elevated systemic inflammation is a strong independent predictor of early mortality in advanced non-small cell lung cancer
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Spatial Immunology in Liver Metastases from Colorectal Carcinoma according to the Histologic Growth Pattern

Garcia-Vicien, Gemma; Mezheyeuski, Artur; Micke, Patrick; Ruiz, Nuria et al.

Part of Cancers, 2022

• DOI for Spatial Immunology in Liver Metastases from Colorectal Carcinoma according to the Histologic Growth Pattern
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Prognostic Significance of the Loss of Heterozygosity of KRAS in Early-Stage Lung Adenocarcinoma

Khadse, Anand; Haakensen, Vilde D.; Silwal-Pandit, Laxmi; Hamfjord, Julian et al.

Part of Frontiers in Oncology, 2022

• DOI for Prognostic Significance of the Loss of Heterozygosity of KRAS in Early-Stage Lung Adenocarcinoma
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Difficulties in diagnostics of lung tumours in biopsies: an interpathologist concordance study evaluating the international diagnostic guidelines

Ericson Lindquist, Kajsa; Ciornei, Cristina; Westbom-Fremer, Sofia; Gudinaviciene, Inga et al.

Part of Journal of Clinical Pathology, p. 302-309, 2022

• DOI for Difficulties in diagnostics of lung tumours in biopsies: an interpathologist concordance study evaluating the international diagnostic guidelines
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Expression of cartilage oligomeric matrix protein in periampullary adenocarcinoma is associated with pancreatobiliary-type morphology, higher levels of fibrosis and immune cell exclusion

Papadakos, Konstantinos S.; Lundgren, Sebastian; Gialeli, Chrysostomi; Micke, Patrick et al.

Part of Oncoimmunology, 2022

• DOI for Expression of cartilage oligomeric matrix protein in periampullary adenocarcinoma is associated with pancreatobiliary-type morphology, higher levels of fibrosis and immune cell exclusion
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Tumour-infiltrating lymphocytes add prognostic information for patients with low-risk DCIS: findings from the SweDCIS randomised radiotherapy trial

Schiza, Aglaia; Thurfjell, Viktoria; Stenmark Tullberg, Axel; Olofsson, Helena et al.

Part of European Journal of Cancer, p. 128-137, 2022

• DOI for Tumour-infiltrating lymphocytes add prognostic information for patients with low-risk DCIS: findings from the SweDCIS randomised radiotherapy trial
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Plasma Proteomic Analysis in Non-Small Cell Lung Cancer Patients Treated with PD-1/PD-L1 Blockade

Eltahir, Mohamed; Isaksson, Johan; Mattsson, Johanna Sofia Margareta; Karre, Klas et al.

Part of Cancers, 2021

• DOI for Plasma Proteomic Analysis in Non-Small Cell Lung Cancer Patients Treated with PD-1/PD-L1 Blockade
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The prognostic impact of the tumour stroma fraction: A machine learning-based analysis in 16 human solid tumour types

Micke, Patrick; Strell, Carina; Mattsson, Johanna Sofia Margareta; Martin-Bernabe, Alfonso et al.

Part of eBioMedicine, 2021

• DOI for The prognostic impact of the tumour stroma fraction: A machine learning-based analysis in 16 human solid tumour types
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Infiltration of NK and plasma cells is associated with a distinct immune subset in non‐small cell lung cancer

Backman, Max; La Fleur, Linnea; Kurppa, Pinja; Djureinovic, Dijana et al.

Part of Journal of Pathology, p. 243-256, 2021

• DOI for Infiltration of NK and plasma cells is associated with a distinct immune subset in non‐small cell lung cancer
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PD-L1 amplification is associated with an immune cell rich phenotype in squamous cell cancer of the lung

Goldmann, Torsten; Marwitz, Sebastian; Nitschkowski, Dorte; Krupar, Rosemarie et al.

Part of Cancer Immunology and Immunotherapy, p. 2577-2587, 2021

• DOI for PD-L1 amplification is associated with an immune cell rich phenotype in squamous cell cancer of the lung
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Evaluation of NTRK immunohistochemistry as a screening method for NTRK gene fusion detection in non-small cell lung cancer

Elfving, Hedvig; Broström, Erika; Moens, Lotte N.J.; Almlöf, Jonas et al.

Part of Lung Cancer, p. 53-59, 2021

• DOI for Evaluation of NTRK immunohistochemistry as a screening method for NTRK gene fusion detection in non-small cell lung cancer

Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene

Doffe, Flora; Carbonnier, Vincent; Tissier, Manon; Leroy, Bernard et al.

Part of Cell Death and Differentiation, p. 1477-1492, 2021

• DOI for Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene
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Plasma Proteome Fingerprints Reveal Distinctiveness and Clinical Outcome of SARS-CoV-2 Infection

Bauer, Wolfgang; Weber, Marcus; Diehl-Wiesenecker, Eva; Galtung, Noa et al.

Part of Viruses, 2021

• DOI for Plasma Proteome Fingerprints Reveal Distinctiveness and Clinical Outcome of SARS-CoV-2 Infection
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Targeting hepatocyte growth factor in epithelial-stromal interactions in an in vitro experimental model of human periodontitis

Yamaguchi, Yoko; Saito, Akira; Horie, Masafumi; Aoki, Akira et al.

Part of Odontology, p. 912-920, 2021

• DOI for Targeting hepatocyte growth factor in epithelial-stromal interactions in an in vitro experimental model of human periodontitis
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An integrative proteomics method identifies a regulator of translation during stem cell maintenance and differentiation

Sabatier, Pierre; Beusch, Christian M.; Saei, Amir A.; Aoun, Mike et al.

Part of Nature Communications, 2021

• DOI for An integrative proteomics method identifies a regulator of translation during stem cell maintenance and differentiation
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Stromal FAP is an independent poor prognosis marker in non-small cell lung adenocarcinoma and associated with p53 mutation

Moreno-Ruiz, Pablo; Corvigno, Sara; te Grootenhuis, Nienke C.; La Fleur, Linnéa et al.

Part of Lung Cancer, p. 10-19, 2021

• DOI for Stromal FAP is an independent poor prognosis marker in non-small cell lung adenocarcinoma and associated with p53 mutation
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FGFR1 overexpression in non-small cell lung cancer is mediated by genetic and epigenetic mechanisms and is a determinant of FGFR1 inhibitor response

Bogatyrova, Olga; Mattsson, Johanna S M; Ross, Edith M.; Sanderson, Michael P. et al.

Part of European Journal of Cancer, p. 136-149, 2021

• DOI for FGFR1 overexpression in non-small cell lung cancer is mediated by genetic and epigenetic mechanisms and is a determinant of FGFR1 inhibitor response
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The Immune Landscape of Colorectal Cancer

Mezheyeuski, Artur; Micke, Patrick; Martin-Bernabe, Alfonso; Backman, Max et al.

Part of Cancers, 2021

• DOI for The Immune Landscape of Colorectal Cancer
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High Density of NRF2 Expression in Malignant Cells Is Associated with Increased Risk of CNS Metastasis in Early-Stage NSCLC

Tsakonas, Georgios; Martin-Bernabe, Alfonso; Rounis, Konstantinos; Moreno-Ruiz, Pablo et al.

Part of Cancers, 2021

• DOI for High Density of NRF2 Expression in Malignant Cells Is Associated with Increased Risk of CNS Metastasis in Early-Stage NSCLC
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TGF-beta-mediated epithelial-mesenchymal transition and tumor-promoting effects in CMT64 cells are reflected in the transcriptomic signature of human lung adenocarcinoma

Miyashita, Naoya; Enokido, Takayoshi; Horie, Masafumi; Fukuda, Kensuke et al.

Part of Scientific Reports, 2021

• DOI for TGF-beta-mediated epithelial-mesenchymal transition and tumor-promoting effects in CMT64 cells are reflected in the transcriptomic signature of human lung adenocarcinoma
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Targeting MARCO and IL-37R on immunosuppressive macrophages in lung cancer blocks regulatory T cells and supports cytotoxic lymphocyte function

La Fleur, Linnea; Botling, Johan; He, Fei; Pelicano, Catarina et al.

Part of Cancer Research, p. 956-967, 2021

• DOI for Targeting MARCO and IL-37R on immunosuppressive macrophages in lung cancer blocks regulatory T cells and supports cytotoxic lymphocyte function

Programmed Cell Death Ligand 1 Expression in Resected Non-Small Cell Lung Cancer

Yu, Hui; Brustugun, Odd Terje; Ekman, Simon; Botling, Johan et al.

Part of Clinical Lung Cancer, p. 555-562, 2021

• DOI for Programmed Cell Death Ligand 1 Expression in Resected Non-Small Cell Lung Cancer

The protein expression profile of ACE2 in human tissues

Noraddin, Feria Hikmet; Méar, Loren; Edvinsson, Åsa; Micke, Patrick et al.

Part of Molecular Systems Biology, 2020

• DOI for The protein expression profile of ACE2 in human tissues

Comprehensive analysis of RNA binding motif protein 3 (RBM3) in non-small cell lung cancer

Salomonsson, Annette; Micke, Patrick; Mattsson, Johanna S M; La Fleur, Linnéa et al.

Part of Cancer Medicine, p. 5609-5619, 2020

• DOI for Comprehensive analysis of RNA binding motif protein 3 (RBM3) in non-small cell lung cancer
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Topographical Distribution and Spatial Interactions of Innate and Semi-Innate Immune Cells in Pancreatic and Other Periampullary Adenocarcinoma

Lundgren, Sebastian; Micke, Patrick; Elebro, Jacob; Heby, Margareta et al.

Part of Frontiers in Immunology, 2020

• DOI for Topographical Distribution and Spatial Interactions of Innate and Semi-Innate Immune Cells in Pancreatic and Other Periampullary Adenocarcinoma
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The Novel Anti-cMet Antibody seeMet 12 Potentiates Sorafenib Therapy and Radiotherapy in a Colorectal Cancer Model

Spiegelberg, Diana; Lundgren Mortensen, Anja Charlotte; Palupi, Kartika Dyah; Micke, Patrick et al.

Part of Frontiers in Oncology, 2020

• DOI for The Novel Anti-cMet Antibody seeMet 12 Potentiates Sorafenib Therapy and Radiotherapy in a Colorectal Cancer Model
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PD-L1 expression in gastroenteropancreatic neuroendocrine neoplasms grade 3

Ali, Abir Salwa; Langer, Seppo W.; Federspiel, Birgitte; Hjortland, Geir Olav et al.

Part of PLOS ONE, 2020

• DOI for PD-L1 expression in gastroenteropancreatic neuroendocrine neoplasms grade 3
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An immune gene expression signature distinguishes central nervous system metastases from primary tumours in non-small-cell lung cancer

Tsakonas, Georgios; Lewensohn, Rolf; Botling, Johan; Ortiz-Villalon, Cristian et al.

Part of European Journal of Cancer, p. 24-34, 2020

• DOI for An immune gene expression signature distinguishes central nervous system metastases from primary tumours in non-small-cell lung cancer
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ASCL1 promotes tumor progression through cell-autonomous signaling and immune modulation in a subset of lung adenocarcinoma

Miyashita, Naoya; Horie, Masafumi; Mikami, Yu; Urushiyama, Hirokazu et al.

Part of Cancer Letters, p. 121-132, 2020

• DOI for ASCL1 promotes tumor progression through cell-autonomous signaling and immune modulation in a subset of lung adenocarcinoma

Platelet-derived growth factor receptor β activation and regulation in murine myelofibrosis

Kramer, Frederike; Dernedde, Jens; Mezheyeuski, Artur; Tauber, Rudolf et al.

Part of Haematologica, p. 2083-2094, 2020

• DOI for Platelet-derived growth factor receptor β activation and regulation in murine myelofibrosis
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Quantitative, qualitative and spatial analysis of lymphocyte infiltration in periampullary and pancreatic adenocarcinoma

Lundgren, Sebastian; Elebro, Jacob; Heby, Margareta; Nodin, Björn et al.

Part of International Journal of Cancer, p. 3461-3473, 2020

• DOI for Quantitative, qualitative and spatial analysis of lymphocyte infiltration in periampullary and pancreatic adenocarcinoma
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Multiplex plasma protein profiling identifies novel markers to discriminate patients with adenocarcinoma of the lung

Djureinovic, Dijana; Pontén, Victor; Landelius, Per; Al Sayegh, Sahar et al.

Part of BMC Cancer, 2019

• DOI for Multiplex plasma protein profiling identifies novel markers to discriminate patients with adenocarcinoma of the lung
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Programmed Cell Death Ligand 1 Immunohistochemistry: A Concordance Study Between Surgical Specimen, Biopsy, and Tissue Microarray

Elfving, Hedvig; Mattsson, Johanna Sofia Margareta; Lindskog, Cecilia; Backman, Max et al.

Part of Clinical Lung Cancer, p. 258-2620, 2019

• DOI for Programmed Cell Death Ligand 1 Immunohistochemistry: A Concordance Study Between Surgical Specimen, Biopsy, and Tissue Microarray

A combined gene expression tool for parallel histological prediction and gene fusion detection in non-small cell lung cancer

Karlsson, Anna; Cirenajwis, Helena; Ericson-Lindquist, Kajsa; Brunnström, Hans et al.

Part of Scientific Reports, 2019

• DOI for A combined gene expression tool for parallel histological prediction and gene fusion detection in non-small cell lung cancer
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Mucin staining is of limited value in addition to basic immunohistochemical analyses in the diagnostics of non-small cell lung cancer

Micke, Patrick; Botling, Johan; Mattsson, Johanna Sofia Margareta; Planck, Maria et al.

Part of Scientific Reports, 2019

• DOI for Mucin staining is of limited value in addition to basic immunohistochemical analyses in the diagnostics of non-small cell lung cancer
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A clonal expression biomarker associates with lung cancer mortality

Biswas, Dhruva; Birkbak, Nicolai J.; Rosenthal, Rachel; Hiley, Crispin T. et al.

Part of Nature Medicine, p. 1540-1548, 2019

• DOI for A clonal expression biomarker associates with lung cancer mortality

c-MET as a biomarker in patients with surgically resected non-small cell lung cancer

Tsakonas, Georgios; Botling, Johan; Micke, Patrick; Rivard, Chris et al.

Part of Lung Cancer, p. 69-74, 2019

• DOI for c-MET as a biomarker in patients with surgically resected non-small cell lung cancer

Immunohistochemical profiles in primary lung cancers and epithelial pulmonary metastases

Vidarsdottir, Halla; Tran, Lena; Nodin, Björn; Jirström, Karin et al.

Part of Human Pathology, p. 221-230, 2019

• DOI for Immunohistochemical profiles in primary lung cancers and epithelial pulmonary metastases

LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer

Cadenas, Cristina; Vosbeck, Sonja; Edlund, Karolina; Grgas, Katharina et al.

Part of International Journal of Cancer, p. 901-915, 2019

• DOI for LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer
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Prognostic Impact of Tumor Cell Programmed Death Ligand 1 Expression and Immune Cell Infiltration in NSCLC

Edlund, Karolina; Madjar, Katrin; Mattsson, Johanna Sofia Margareta; Djureinovic, Dijana et al.

Part of Journal of Thoracic Oncology, p. 628-640, 2019

• DOI for Prognostic Impact of Tumor Cell Programmed Death Ligand 1 Expression and Immune Cell Infiltration in NSCLC
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Real-world prevalence of programmed death ligand 1 expression in locally advanced or metastatic non small-cell lung cancer: The global, multicenter EXPRESS study

Dietel, M.; Savelov, N.; Salanova, R.; Micke, Patrick et al.

Part of Lung Cancer, p. 174-179, 2019

• DOI for Real-world prevalence of programmed death ligand 1 expression in locally advanced or metastatic non small-cell lung cancer: The global, multicenter EXPRESS study

NK- and T-cell subsets in malignant mesothelioma patients: Baseline pattern and changes in the context of anti-CTLA-4 therapy

Sottile, Rosa; Tannazi, Milad; Johansson, Maria H.; Cristiani, Costanza Maria et al.

Part of International Journal of Cancer, p. 2238-2248, 2019

• DOI for NK- and T-cell subsets in malignant mesothelioma patients: Baseline pattern and changes in the context of anti-CTLA-4 therapy

Mutation patterns in a population-based non-small cell lung cancer cohort and prognostic impact of concomitant mutations in KRAS and TP53 or STK11

La Fleur, Linnea; Falk-Sörqvist, Elin; Smeds, Patrik; Berglund, Anders et al.

Part of Lung Cancer, p. 50-58, 2019

• DOI for Mutation patterns in a population-based non-small cell lung cancer cohort and prognostic impact of concomitant mutations in KRAS and TP53 or STK11
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Cancer stemness, intratumoral heterogeneity, and immune response across cancers

Miranda, Alex; Hamilton, Phineas T.; Zhang, Allen W.; Pattnaik, Swetansu et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 9020-9029, 2019

• DOI for Cancer stemness, intratumoral heterogeneity, and immune response across cancers

Multispectral imaging for quantitative and compartment-specific immune infiltrates reveals distinct immune profiles that classify lung cancer patients

Mezheyeuski, Artur; Bergsland, Christian Holst; Backman, Max; Djureinovic, Dijana et al.

Part of Journal of Pathology, p. 421-431, 2018

• DOI for Multispectral imaging for quantitative and compartment-specific immune infiltrates reveals distinct immune profiles that classify lung cancer patients

Expression of scavenger receptor MARCO defines a targetable tumor-associated macrophage subset in non-small cell lung cancer

La Fleur, Linnea; Boura, Vanessa F.; Alexeyenko, Andrey; Berglund, Anders et al.

Part of International Journal of Cancer, p. 1741-1752, 2018

• DOI for Expression of scavenger receptor MARCO defines a targetable tumor-associated macrophage subset in non-small cell lung cancer

The Heidelberg compact electron beam ion traps

Micke, Patrick; Kühn, S; Buchauer, L; Harries, J R et al.

Part of Review of Scientific Instruments, 2018

• DOI for The Heidelberg compact electron beam ion traps

COX-2 expression and effects of celecoxib in addition to standard chemotherapy in advanced non-small cell lung cancer.

Gulyas, Miklos; Mattsson, Johanna Sofia Margareta; Lindgren, Andrea; Ek, Lars et al.

Part of Acta Oncologica, p. 244-250, 2018

• DOI for COX-2 expression and effects of celecoxib in addition to standard chemotherapy in advanced non-small cell lung cancer.

Comparison of Three Different TTF-1 Clones in Resected Primary Lung Cancer and Epithelial Pulmonary Metastase

Vidarsdottir, Halla; Tran, Lena; Nodin, Björn; Jirström, Karin et al.

Part of American Journal of Clinical Pathology, p. 533-544, 2018

• DOI for Comparison of Three Different TTF-1 Clones in Resected Primary Lung Cancer and Epithelial Pulmonary Metastase

LMO7 and LIMCH1 interact with LRIG proteins in lung cancer, with prognostic implications for early-stage disease

Karlsson, Terese; Kvarnbrink, Samuel; Holmlund, Camilla; Botling, Johan et al.

Part of Lung Cancer, p. 174-184, 2018

• DOI for LMO7 and LIMCH1 interact with LRIG proteins in lung cancer, with prognostic implications for early-stage disease

An Integrative Analysis of Transcriptome and Epigenome Features of ASCL1-Positive Lung Adenocarcinomas

Miyashita, Naoya; Horie, Masafumi; Suzuki, Hiroshi I.; Yoshihara, Masahito et al.

Part of Journal of Thoracic Oncology, p. 1676-1691, 2018

• DOI for An Integrative Analysis of Transcriptome and Epigenome Features of ASCL1-Positive Lung Adenocarcinomas

An integrative transcriptome analysis reveals a functional role for thyroid transcription factor-1 in small cell lung cancer

Horie, Masafumi; Miyashita, Naoya; Mattsson, Johanna Sofia Margareta; Mikami, Yu et al.

Part of Journal of Pathology, p. 154-165, 2018

• DOI for An integrative transcriptome analysis reveals a functional role for thyroid transcription factor-1 in small cell lung cancer

Radionuclide Therapy of HER2-Expressing Human Xenografts Using Affibody-Based Peptide Nucleic Acid-Mediated Pretargeting: In Vivo Proof of Principle

Westerlund, Kristina; Altai, Mohamed; Mitran, Bogdan; Konijnenberg, Mark et al.

Part of Journal of Nuclear Medicine, p. 1092-1098, 2018

• DOI for Radionuclide Therapy of HER2-Expressing Human Xenografts Using Affibody-Based Peptide Nucleic Acid-Mediated Pretargeting: In Vivo Proof of Principle

Detection of autoantibodies against cancer-testis antigens in non-small cell lung cancer

Djureinovic, Dijana; Dodig-Crnkovic, Tea; Hellström, Cecilia; Holgersson, Georg et al.

Part of Lung Cancer, p. 157-163, 2018

• DOI for Detection of autoantibodies against cancer-testis antigens in non-small cell lung cancer

Digital multiplex immunofluorescence analysis identifies immune profiles in the tumor stroma associated with clinical outcome

Mezheyeuski, Artur; Bergsland, Christian; Backman, Max; Sjöblom, Tobias et al.

Part of CANCER IMMUNOLOGY RESEARCH, 2018

• DOI for Digital multiplex immunofluorescence analysis identifies immune profiles in the tumor stroma associated with clinical outcome

30O Real-world prevalence of PD-L1 expression in locally advanced or metastatic non-small cell lung cancer (NSCLC): The global, multicentre EXPRESS study

Dietel, M.; Savelov, N.; Salanova, R.; Micke, Patrick et al.

Part of Journal of Thoracic Oncology, 2018

• DOI for 30O Real-world prevalence of PD-L1 expression in locally advanced or metastatic non-small cell lung cancer (NSCLC): The global, multicentre EXPRESS study

Digital pathology 2.0: a deep learning image analysis tool to identify lung cancer in human tissue samples

Micke, Patrick; Björk, L.; Backman, M.; Elfving, H. et al.

Part of Virchows Archiv, 2018

Real-World Prevalence of PD-L1 Expression in Advanced NoneSmall-Cell Lung Cancer: The Global, Multicenter EXPRESS Study

Salanova, R.; Dietel, M.; Savelov, N.; Micke, Patrick et al.

Part of Journal of Thoracic Oncology, 2018

Reaching the limits of prognostication in non-small cell lung cancer: an optimized biomarker panel fails to outperform clinical parameters.

Grinberg, Marianna; Djureinovic, Dijana; Brunnström, Hans R R; Mattsson, Johanna Sofia Margareta et al.

Part of Modern Pathology, p. 964-977, 2017

• DOI for Reaching the limits of prognostication in non-small cell lung cancer: an optimized biomarker panel fails to outperform clinical parameters.

The integrative clinical impact of tumor-infiltrating T lymphocytes and NK cells in relation to B lymphocyte and plasma cell density in esophageal and gastric adenocarcinoma

Svensson, Maria C.; Warfvinge, Carl Fredrik; Fristedt, Richard; Hedner, Charlotta et al.

Part of Oncotarget, p. 72108-72126, 2017

• DOI for The integrative clinical impact of tumor-infiltrating T lymphocytes and NK cells in relation to B lymphocyte and plasma cell density in esophageal and gastric adenocarcinoma
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Integrative analysis of genome-wide gene copy number changes and gene expression in non-small cell lung cancer

Jabs, Verena; Edlund, Karolina; Koenig, Helena; Grinberg, Marianna et al.

Part of PLOS ONE, 2017

• DOI for Integrative analysis of genome-wide gene copy number changes and gene expression in non-small cell lung cancer
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Whole-tissue biopsy phenotyping of three-dimensional tumours reveals patterns of cancer heterogeneity

Tanaka, Nobuyuki; Kanatani, Shigeaki; Tomer, Raju; Sahlgren, Cecilia et al.

Part of Nature Biomedical Engineering, p. 796-806, 2017

• DOI for Whole-tissue biopsy phenotyping of three-dimensional tumours reveals patterns of cancer heterogeneity

PD-L1 immunohistochemistry in clinical diagnostics of lung cancer: inter-pathologist variability is higher than assay variability

Brunnstrom, Hans; Johansson, Anna; Westbom-Fremer, Sofia; Backman, Max et al.

Part of Modern Pathology, p. 1411-1421, 2017

• DOI for PD-L1 immunohistochemistry in clinical diagnostics of lung cancer: inter-pathologist variability is higher than assay variability

Somatic Ephrin Receptor Mutations Are Associated with Metastasis in Primary Colorectal Cancer

Mathot, Lucy; Kundu, Snehangshu; Ljungström, Viktor; Svedlund, Jessica et al.

Part of Cancer Research, p. 1730-1740, 2017

• DOI for Somatic Ephrin Receptor Mutations Are Associated with Metastasis in Primary Colorectal Cancer

RANK rewires energy homeostasis in lung cancer cells and drives primary lung cancer

Rao, Shuan; Sigl, Verena; Wimmer, Reiner Alois; Novatchkova, Maria et al.

Part of Genes & Development, p. 2099-2112, 2017

• DOI for RANK rewires energy homeostasis in lung cancer cells and drives primary lung cancer
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A pathology atlas of the human cancer transcriptome

Uhlen, Mathias; Zhang, Cheng; Lee, Sunjae; Sjöstedt, Evelina et al.

Part of Science, 2017

• DOI for A pathology atlas of the human cancer transcriptome

Gene Expression Profiling of Large Cell Lung Cancer Links Transcriptional Phenotypes to the New Histological WHO 2015 Classification

Karlsson, Anna; Brunnström, Hans; Micke, Patrick; Veerla, Srinivas et al.

Part of Journal of Thoracic Oncology, p. 1257-1267, 2017

• DOI for Gene Expression Profiling of Large Cell Lung Cancer Links Transcriptional Phenotypes to the New Histological WHO 2015 Classification
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Mutation Profiling by Targeted Next Generation Sequencing of an Unselected NSCLC Cohort

La Fleur, Linnea; Falk-Sörqvist, Elin; Smeds, Patrik; Sundström, Magnus et al.

Part of Journal of Thoracic Oncology, 2017

• DOI for Mutation Profiling by Targeted Next Generation Sequencing of an Unselected NSCLC Cohort

Establishing Reflex NGS Testing in NSCLC in a Regional Network of County Hospitals in Central Sweden

Isaksson, Johan; Willen, Linda; La Fleur, Linnea; Mindus, Stephanie et al.

Part of Journal of Thoracic Oncology, 2017

• DOI for Establishing Reflex NGS Testing in NSCLC in a Regional Network of County Hospitals in Central Sweden

PD-L1 immunohistochemistry in clinical diagnostics: Inter-pathologist variability is as high as assay variability

Micke, Patrick; Johansson, Anna; Westbom-Fremer, Anna; Backman, Max et al.

Part of Journal of Clinical Oncology, 2017

• DOI for PD-L1 immunohistochemistry in clinical diagnostics: Inter-pathologist variability is as high as assay variability

Integrative CAGE and DNA Methylation Profiling Identify Epigenetically Regulated Genes in NSCLC

Horie, Masafumi; Kaczkowski, Bogumil; Ohshima, Mitsuhiro; Matsuzaki, Hirotaka et al.

Part of Molecular Cancer Research, p. 1354-1365, 2017

• DOI for Integrative CAGE and DNA Methylation Profiling Identify Epigenetically Regulated Genes in NSCLC

Antitumoral effect and reduced systemic toxicity in mice after intra-tumoral injection of an in vivo solidifying calcium sulfate formulation with docetaxel

Sandelin, Martin; Gruden, S.; Räsänen, Veera; Micke, Patrick et al.

Part of Annals of Oncology, 2017

• DOI for Antitumoral effect and reduced systemic toxicity in mice after intra-tumoral injection of an in vivo solidifying calcium sulfate formulation with docetaxel

The clinical impact of tumour-infiltrating lymphocytes in colorectal cancer differs by anatomical subsite: A cohort study

Berntsson, Jonna; Svensson, Maria C.; Leandersson, Karin; Nodin, Bjorn et al.

Part of International Journal of Cancer, p. 1654-1666, 2017

• DOI for The clinical impact of tumour-infiltrating lymphocytes in colorectal cancer differs by anatomical subsite: A cohort study
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Antitumoral effect and reduced systemic toxicity in mice after intra-tumoral injection of an in vivo solidifying calcium sulfate formulation with docetaxel

Grudén, Stefan; Sandelin, Martin; Rasanen, Veera; Micke, Patrick et al.

Part of European journal of pharmaceutics and biopharmaceutics, p. 186-193, 2017

• DOI for Antitumoral effect and reduced systemic toxicity in mice after intra-tumoral injection of an in vivo solidifying calcium sulfate formulation with docetaxel
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Prognostic impact of tumour-associated B cells and plasma cells in epithelial ovarian cancer

Lundgren, Sebastian; Berntsson, Jonna; Nodin, Björn; Micke, Patrick et al.

Part of Journal of Ovarian Research, 2016

• DOI for Prognostic impact of tumour-associated B cells and plasma cells in epithelial ovarian cancer
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Transcriptome analysis of periodontitis-associated fibroblasts by CAGE sequencing identified DLX5 and RUNX2 long variant as novel regulators involved in periodontitis

Horie, Masafumi; Yamaguchi, Yoko; Saito, Akira; Nagase, Takahide et al.

Part of Scientific Reports, 2016

• DOI for Transcriptome analysis of periodontitis-associated fibroblasts by CAGE sequencing identified DLX5 and RUNX2 long variant as novel regulators involved in periodontitis
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Inconsistent results in the analysis of ALK rearrangements in non-small cell lung cancer

Mattsson, Johanna Sofia Margareta; Brunnström, Hans; Jabs, Verena; Edlund, Karolina et al.

Part of BMC Cancer, 2016

• DOI for Inconsistent results in the analysis of ALK rearrangements in non-small cell lung cancer
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The protein kinase LKB1 negatively regulates bone morphogenetic protein receptor signaling

Raja, Erna; Tzavlaki, Kalliopi; Vuilleumier, Robin; Edlund, Karolina et al.

Part of Oncotarget, p. 1120-1143, 2016

• DOI for The protein kinase LKB1 negatively regulates bone morphogenetic protein receptor signaling
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Epsin Family Member 3 and Ribosome-Related Genes Are Associated with Late Metastasis in Estrogen Receptor-Positive Breast Cancer and Long-Term Survival in Non-Small Cell Lung Cancer Using a Genome-Wide Identification and Validation Strategy

Hellwig, Birte; Madjar, Katrin; Edlund, Karolina; Marchan, Rosemarie et al.

Part of PLOS ONE, 2016

• DOI for Epsin Family Member 3 and Ribosome-Related Genes Are Associated with Late Metastasis in Estrogen Receptor-Positive Breast Cancer and Long-Term Survival in Non-Small Cell Lung Cancer Using a Genome-Wide Identification and Validation Strategy
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Various Antibody Clones of Napsin A, Thyroid Transcription Factor 1, and p40 and Comparisons With Cytokeratin 5 and p63 in Histopathologic Diagnostics of Non-Small Cell Lung Carcinoma

Tran, Lena; Mattsson, Johanna Sofia Margareta; Nodin, Björn; Jönsson, Per et al.

Part of Applied immunohistochemistry & molecular morphology (Print), p. 648-659, 2016

• DOI for Various Antibody Clones of Napsin A, Thyroid Transcription Factor 1, and p40 and Comparisons With Cytokeratin 5 and p63 in Histopathologic Diagnostics of Non-Small Cell Lung Carcinoma

Profiling cancer testis antigens in non-small-cell lung cancer

Djureinovic, Dijana; Hallström, Bjorn M.; Horie, Masafumi; Mattsson, Johanna Sofia Margareta et al.

Part of JCI INSIGHT, 2016

• DOI for Profiling cancer testis antigens in non-small-cell lung cancer

Prognostic impact of tumour-associated B cells and plasma cells in oesophageal and gastric adenocarcinoma

Fristedt, Richard; Borg, David; Hedner, Charlotta; Berntsson, Jonna et al.

Part of Journal of Gastrointestinal Oncology, p. 848-859, 2016

• DOI for Prognostic impact of tumour-associated B cells and plasma cells in oesophageal and gastric adenocarcinoma

The Impact of the Fourth Edition of the WHO Classification of Lung Tumours on Histological Classification of Resected Pulmonary NSCCs

Micke, Patrick; Mattsson, Johanna Sofia Margareta; Djureinovic, Dijana; Nodin, Björn et al.

Part of Journal of Thoracic Oncology, p. 862-872, 2016

• DOI for The Impact of the Fourth Edition of the WHO Classification of Lung Tumours on Histological Classification of Resected Pulmonary NSCCs

Prognostic impact of tumour-infiltrating B cells and plasma cells in colorectal cancer

Berntsson, Jonna; Nodin, Björn; Eberhard, Jakob; Micke, Patrick et al.

Part of International Journal of Cancer, p. 1129-1139, 2016

• DOI for Prognostic impact of tumour-infiltrating B cells and plasma cells in colorectal cancer

Prognostic impact of tumor-associated B-cells and plasma cells in esophageal and gastric adenocarcinoma

Fristedt, Richard; Hedner, Charlotta; Borg, David; Nodin, Björn et al.

Part of Journal of Clinical Oncology, 2016

Fibroblast VEGF-receptor 1 expression as molecular target in periodontitis

Ohshima, Mitsuhiro; Yamaguchi, Yoko; Ambe, Kimiharu; Horie, Masafumi et al.

Part of Journal of Clinical Periodontology, p. 128-137, 2016

• DOI for Fibroblast VEGF-receptor 1 expression as molecular target in periodontitis

Microsatellite instability and mutations in BRAF and KRAS are significant predictors of disseminated disease in colon cancer

Birgisson, Helgi; Edlund, Karolina; Wallin, Ulrik; Påhlman, Lars et al.

Part of BMC Cancer, 2015

• DOI for Microsatellite instability and mutations in BRAF and KRAS are significant predictors of disseminated disease in colon cancer
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The Identification of Therapeutic Targets in Lung Cancer Based on Transcriptomic and Proteomic Characterization of Cancer-Testis Antigens

Djureinovic, Dijana; Hallström, Björn; Mattsson, Johanna Sofia Margareta; La Fleur, Linnea et al.

Part of Journal of Thoracic Oncology, 2015

LRIG1 is a prognostic biomarker in non-small cell lung cancer

Kvarnbrink, Samuel; Karlsson, Terese; Edlund, Karolina; Botling, Johan et al.

Part of Acta Oncologica, p. 1113-1119, 2015

• DOI for LRIG1 is a prognostic biomarker in non-small cell lung cancer

Prognostic impact of COX-2 in non-small cell lung cancer: A comprehensive compartment-specific evaluation of tumor and stromal cell expression

Mattsson, Johanna Sofia Margareta; Bergman, Bengt; Grinberg, Marianna; Edlund, Karolina et al.

Part of Cancer Letters, p. 837-845, 2015

• DOI for Prognostic impact of COX-2 in non-small cell lung cancer: A comprehensive compartment-specific evaluation of tumor and stromal cell expression

Mutation Profiling by Targeted Next-Generation Sequencing for Diagnostics and Patient Cohort Screening in FFPE NSCLC Samples

La Fleur, Linnea; Moens, Lotte; Falk-Sörqvist, Elin; Sundström, Magnus et al.

Part of Journal of Thoracic Oncology, 2015

The role of the p53 target Wig-1 in senescence and cancer

Jerhammar, Fredrik; Bersani, Cinzia; Djureinovic, Dijana; Micke, Patrick et al.

Part of Cancer Research, p. 110, 2015

• DOI for The role of the p53 target Wig-1 in senescence and cancer

The Crux of Molecular Prognostications in NSCLC: An Optimized Biomarker Panel Fails to Outperform Clinical Parameters

Djureinovic, Dijana; Grinberg, Marianna; Mattsson, Johanna Sofia Margareta; Edlund, Karolina et al.

Part of Journal of Thoracic Oncology, 2015

ALK Rearrangements in Non-Small Cell Lung Cancer: Comprehensive Integration of Genomic, Gene Expression and Protein Analysis

Mattsson, Johanna S. M.; Svensson, Maria A.; Hallström, Björn; Koyi, Hirsh et al.

Part of Journal of Thoracic Oncology, 2015

COX-2 Expression Does Not Predict Outcome of Celecoxib in Addition to Standard Chemotherapy in Advanced Non-Small Cell Lung Cancer

Gulyas, Miklos; Mattsson, Johanna S. M.; Lindgren, Andrea; Sederholm, Christer et al.

Part of Journal of Thoracic Oncology, 2015

Clinical Validation of HaloPlex Targeted Resequencing in Formalin-Fixed, Paraffin-Embedded (FFPE) Cancer Biopsies

Moens, Lotte. N.; Falk-Sörqvist, Elin; La Fleur, Linnea; Mattsson, Johanna et al.

Part of Journal of Molecular Diagnostics, p. 822-822, 2015

HaloPlex Targeted Resequencing for Mutation Detection in Clinical Formalin-Fixed, Paraffin-Embedded Tumor Samples

Moens, Lotte N. J.; Falk-Sörqvist, Elin; Ljungström, Viktor; Mattsson, Johanna et al.

Part of Journal of Molecular Diagnostics, p. 729-739, 2015

• DOI for HaloPlex Targeted Resequencing for Mutation Detection in Clinical Formalin-Fixed, Paraffin-Embedded Tumor Samples

Identification of sample annotation errors in gene expression datasets

Lohr, Miriam; Hellwig, Birte; Edlund, Karolina; Mattsson, Johanna S. M. et al.

Part of Archives of Toxicology, p. 2265-2272, 2015

• DOI for Identification of sample annotation errors in gene expression datasets
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Patients with Non-small Cell Lung Cancer Analyzed for EGFR: Adherence to Guidelines, Prevalence and Outcome

Sandelin, Martin; Berglund, Anders; Sundström, Magnus; Micke, Patrick et al.

Part of Anticancer Research, p. 3979-3985, 2015

1p36 deletion is a marker for tumour dissemination in microsatellite stable stage II-III colon cancer

Mayrhofer, Markus; Kultima, Hanna Göransson; Birgisson, Helgi; Sundström, Magnus et al.

Part of BMC Cancer, p. 872, 2014

• DOI for 1p36 deletion is a marker for tumour dissemination in microsatellite stable stage II-III colon cancer
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Aberrantly activated claudin 6 and 18.2 as potential therapy targets in non-small-cell lung cancer

Micke, Patrick; Mattsson, Johanna Sofia Margareta; Edlund, Karolina; Lohr, Miriam et al.

Part of International Journal of Cancer, p. 2206-2214, 2014

• DOI for Aberrantly activated claudin 6 and 18.2 as potential therapy targets in non-small-cell lung cancer

The lung-specific proteome defined by integration of transcriptomics and antibody-based profiling

Lindskog, Cecilia; Fagerberg, Linn; Hallstrom, Bjorn; Edlund, Karolina et al.

Part of The FASEB Journal, p. 5184-5196, 2014

• DOI for The lung-specific proteome defined by integration of transcriptomics and antibody-based profiling

Genomic and Transcriptional Alterations in Lung Adenocarcinoma in Relation to Smoking History

Karlsson, Anna; Ringner, Markus; Lauss, Martin; Botling, Johan et al.

Part of Clinical Cancer Research, p. 4912-4924, 2014

• DOI for Genomic and Transcriptional Alterations in Lung Adenocarcinoma in Relation to Smoking History

An Integrative Analysis of the Tumorigenic Role of TAZ in Human Non-Small Cell Lung Cancer

Noguchi, Satoshi; Saito, Akira; Horie, Masafumi; Mikami, Yu et al.

Part of Clinical Cancer Research, p. 4660-4672, 2014

• DOI for An Integrative Analysis of the Tumorigenic Role of TAZ in Human Non-Small Cell Lung Cancer

A systematic analysis of commonly used antibodies in cancer diagnostics

Gremel, Gabriela; Bergman, Julia; Djureinovic, Dijana; Edqvist, Per-Henrik et al.

Part of Histopathology, p. 293-305, 2014

• DOI for A systematic analysis of commonly used antibodies in cancer diagnostics

In situ mutation detection and visualization of intratumor heterogeneity for cancer research and diagnostics

Grundberg, Ida; Kiflemariam, Sara; Mignardi, Marco; Imgenberg-Kreuz, Juliana et al.

Part of Oncotarget, p. 2407-2418, 2013

The prognostic relevance of tumour-infiltrating plasma cells and immunoglobulin kappa C indicates an important role of the humoral immune response in non-small cell lung cancer

Lohr, Miriam; Edlund, Karolina; Botling, Johan; Hammad, Seddik et al.

Part of Cancer Letters, p. 222-228, 2013

• DOI for The prognostic relevance of tumour-infiltrating plasma cells and immunoglobulin kappa C indicates an important role of the humoral immune response in non-small cell lung cancer

Biomarker discovery in non-small cell lung cancer: integrating gene expression profiling, meta-analysis and tissue microarray validation

Botling, Johan; Edlund, Karolina; Lohr, Miriam; Hellwig, Birte et al.

Part of Clinical Cancer Research, p. 194-204, 2013

• DOI for Biomarker discovery in non-small cell lung cancer: integrating gene expression profiling, meta-analysis and tissue microarray validation

Genomic and Transcriptional Alterations in Lung Adenocarcinoma in Relation to EGFR and KRAS Mutation Status

Planck, Maria; Edlund, Karolina; Botling, Johan; Micke, Patrick et al.

Part of PLOS ONE, 2013

• DOI for Genomic and Transcriptional Alterations in Lung Adenocarcinoma in Relation to EGFR and KRAS Mutation Status
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Landscape of somatic allelic imbalances and copy number alterations in human lung carcinoma

Staaf, Johan; Isaksson, Sofi; Karlsson, Anna; Jönsson, Mats et al.

Part of International Journal of Cancer, p. 2020-2031, 2013

• DOI for Landscape of somatic allelic imbalances and copy number alterations in human lung carcinoma

IGKC and Prognosis in Breast Cancer-Letter

Schmidt, Marcus; Micke, Patrick; Hengstler, Jan G.

Part of Clinical Cancer Research, p. 304-304, 2013

• DOI for IGKC and Prognosis in Breast Cancer-Letter

Targeted Resequencing of Formalin-Fixed, Paraffin-Embedded (FFPE) Specimens for Mutation Diagnostics in Solid Tumors

Botling, Johan; Moens, Lotte N.; Sorqvist, Elin Falk; Sundström, Magnus et al.

Part of Journal of Molecular Diagnostics, p. 916-916, 2013

Interactions between LRIG proteins and LMO7 and the expression of LMO7 in human lung cancer.

Karlsson, Terese; Kvarnbrink, Samuel; Holmlund, Camilla; Botling, Johan et al.

Part of Cancer Research, 2013

• DOI for Interactions between LRIG proteins and LMO7 and the expression of LMO7 in human lung cancer.

In vitro autoradiography of carcinoembryonic antigen in tissue from patients with colorectal cancer using multifunctional antibody TF2 and ^67/68Ga-labeled haptens by pretargeting

Hall, Håkan; Velikyan, Irina; Blom, Elisabeth; Ulin, Johan et al.

Part of American journal of nuclear medicine and molecular imaging, p. 141-150, 2012

CD99 is a novel prognostic stromal marker in non-small cell lung cancer

Edlund, Karolina; Lindskog, Cecilia; Saito, Akira; Berglund, Anders et al.

Part of International Journal of Cancer, p. 2264-2273, 2012

• DOI for CD99 is a novel prognostic stromal marker in non-small cell lung cancer

Consistent mutation status within histologically heterogeneous lung cancer lesions

Mattsson, Johanna Sofia Margareta; Imgenberg-Kreuz, Juliana; Edlund, Karolina; Botling, Johan et al.

Part of Histopathology, p. 744-748, 2012

• DOI for Consistent mutation status within histologically heterogeneous lung cancer lesions

A comprehensive analysis of human gene expression profiles identifies stromal immunoglobulin kappa C as a compatible prognostic marker in human solid tumors

Schmidt, Marcus; Hellwig, Birte; Hammad, Seddik; Othman, Amnah et al.

Part of Clinical Cancer Research, p. 2695-2703, 2012

• DOI for A comprehensive analysis of human gene expression profiles identifies stromal immunoglobulin kappa C as a compatible prognostic marker in human solid tumors

Data-driven unbiased curation of the TP53 tumor suppressor gene mutation database and validation by ultradeep sequencing of human tumors

Edlund, Karolina; Larsson, Ola; Ameur, Adam; Bunikis, Ignas et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 9551-9556, 2012

• DOI for Data-driven unbiased curation of the TP53 tumor suppressor gene mutation database and validation by ultradeep sequencing of human tumors

Immunoglobulin kappa chain as an immunologic biomarker of prognosis and chemotherapy response in solid tumors

Schmidt, Marcus; Micke, Patrick; Gehrmann, Mathias; Hengstler, Jan G

Part of Oncoimmunology, p. 1156-1158, 2012

• DOI for Immunoglobulin kappa chain as an immunologic biomarker of prognosis and chemotherapy response in solid tumors

Allele-specific copy number analysis of tumor samples with aneuploidy and tumor heterogeneity

Rasmussen, Markus; Sundström, Magnus; Kultima, Hanna Göransson; Botling, Johan et al.

Part of Genome Biology, 2011

• DOI for Allele-specific copy number analysis of tumor samples with aneuploidy and tumor heterogeneity
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Gene Copy Number Aberrations Are Associated with Survival in Histologic Subgroups of Non-small Cell Lung Cancer

Micke, Patrick; Edlund, Karolina; Holmberg, Lars; Göransson Kultima, Hanna et al.

Part of Journal of Thoracic Oncology, p. 1833-1840, 2011

• DOI for Gene Copy Number Aberrations Are Associated with Survival in Histologic Subgroups of Non-small Cell Lung Cancer

Traditional European Medicine: Hildegard von Bingen and beyond

Micke, O.; Büntzel, J.; Mücke, R.; Micke, Patrick et al.

Part of Trace elements and electrolytes, p. 150-155, 2011

• DOI for Traditional European Medicine: Hildegard von Bingen and beyond

Targeted resequencing of candidate genes using Selector Probes

Johansson, Henrik; Isaksson, Magnus; Sörqvist, Elin Falk; Roos, F. et al.

Part of Nucleic Acids Research, 2011

• DOI for Targeted resequencing of candidate genes using Selector Probes

Fresh frozen tissue: RNA extraction and quality control

Botling, Johan; Micke, Patrick

Part of Methods in Molecular Biology, p. 405-413, 2011

• DOI for Fresh frozen tissue: RNA extraction and quality control

Biobanking of fresh frozen tissue from clinical surgical specimens: transport logistics, sample selection, and histologic characterization.

Botling, Johan; Micke, Patrick

Part of Methods in Molecular Biology, p. 299-306, 2011

• DOI for Biobanking of fresh frozen tissue from clinical surgical specimens: transport logistics, sample selection, and histologic characterization.

KRAS analysis in colorectal carcinoma: analytical aspects of Pyrosequencing and allele-specific PCR in clinical practice

Sundström, Magnus; Edlund, Karolina; Lindell, Monica; Glimelius, Bengt et al.

Part of BMC Cancer, p. 660, 2010

• DOI for KRAS analysis in colorectal carcinoma: analytical aspects of Pyrosequencing and allele-specific PCR in clinical practice

TGF-beta Signaling in Gingival Fibroblast-Epithelial Interaction

Ohshima, M.; Yamaguchi, Y.; Matsumoto, N.; Micke, Patrick et al.

Part of Journal of Dental Research, p. 1315-1321, 2010

• DOI for TGF-beta Signaling in Gingival Fibroblast-Epithelial Interaction

Forkhead box F1 regulates tumor-promoting properties of cancer-associated fibroblasts in lung cancer

Saito, Roy-Akira; Micke, Patrick; Paulsson, Janna; Augsten, Martin et al.

Part of Cancer Research, p. 2644-2654, 2010

• DOI for Forkhead box F1 regulates tumor-promoting properties of cancer-associated fibroblasts in lung cancer

Gene Copy Number Aberrations are Associated with Survival in Histological Subgroups of Non Small Cell Lung Cancer

Micke, Patrick; Holmberg, L.; Edlund, Karolina; Lambe, M. et al.

Part of Journal of Molecular Diagnostics, p. 909-909, 2010

Complementary and alternative medicine in lung cancer patients: a neglected phenomenon?

Micke, O.; Buntzel, J.; Kisters, K.; Schafer, U. et al.

Part of Frontiers of radiation therapy and oncology, p. 198-205, 2010

• DOI for Complementary and alternative medicine in lung cancer patients: a neglected phenomenon?

CXCL14 is an autocrine growth factor for fibroblasts and acts as a multi-modal stimulator of prostate tumor growth

Augsten, Martin; Hägglöf, Christina; Olsson, Eleonor; Stolz, Claudia et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 3414-3419, 2009

• DOI for CXCL14 is an autocrine growth factor for fibroblasts and acts as a multi-modal stimulator of prostate tumor growth

TA-MUC1 epitope in non-small cell lung cancer

Kuemmel, Andreas; Single, Kristjan; Bittinger, Fernando; Faldum, Andreas et al.

Part of Lung Cancer, p. 98-105, 2009

• DOI for TA-MUC1 epitope in non-small cell lung cancer

Regulation of tyrosine phosphatases in the adventitia during vascular remodelling

Micke, Patrick; Hackbusch, Daniel; Mercan, Sibel; Stawowy, Philipp et al.

Part of Biochemical and Biophysical Research Communications - BBRC, p. 678-684, 2009

• DOI for Regulation of tyrosine phosphatases in the adventitia during vascular remodelling

bFGF rescues imatinib/STI571-induced apoptosis of sis-NIH3T3 fibroblasts.

Ohshima, Mitsuhiro; Yamaguchi, Yoko; Kappert, Kai; Micke, Patrick et al.

Part of Biochemical and Biophysical Research Communications - BBRC, p. 165-170, 2009

• DOI for bFGF rescues imatinib/STI571-induced apoptosis of sis-NIH3T3 fibroblasts.

Quantification of normal cell fraction and copy number neutral LOH in clinical lung cancer samples using SNP array data

Göransson, Hanna; Edlund, Karolina; Rydåker, Maria; Rasmussen, Markus et al.

Part of PloS one, 2009

• DOI for Quantification of normal cell fraction and copy number neutral LOH in clinical lung cancer samples using SNP array data

Predictive factors for the use of complementary and alternative medicine (CAM) in radiation oncology

Micke, Oliver; Bruns, Frank; Glatzel, Michael; Schoenekaes, Klaus et al.

Part of European Journal of Integrative Medicine, p. 19-25, 2009

• DOI for Predictive factors for the use of complementary and alternative medicine (CAM) in radiation oncology

A novel strategy based on histological protein profiling in-silico for identifying potential biomarkers in urinary bladder cancer

Segersten, M. Ulrika; Edlund, E. Karolina; Micke, Patrick; de la Torre, Manuel et al.

Part of BJU International, p. 1780-1785, 2009

• DOI for A novel strategy based on histological protein profiling in-silico for identifying potential biomarkers in urinary bladder cancer

Prognostic significance of stromal platelet-derived growth factor beta-receptor expression in human breast cancer

Paulsson, Janna; Sjöblom, Tobias; Micke, Patrick; Pontén, Fredrik et al.

Part of American Journal of Pathology, p. 334-341, 2009

• DOI for Prognostic significance of stromal platelet-derived growth factor beta-receptor expression in human breast cancer

Impact of thawing on RNA integrity and gene expression analysis in fresh frozen tissue

Botling, Johan; Edlund, Karolina; Segersten, Ulrika; Tahmasebpoor, Simin et al.

Part of Diagnostic molecular pathology (Print), p. 44-52, 2009

• DOI for Impact of thawing on RNA integrity and gene expression analysis in fresh frozen tissue

In vitro characterization of the cytokine profile of the epithelial cell rests of Malassez

Ohshima, Mitsuhiro; Yamaguchi, Yoko; Micke, Patrick; Abiko, Yoshimitsu et al.

Part of Journal of Periodontology, p. 912-919, 2008

• DOI for In vitro characterization of the cytokine profile of the epithelial cell rests of Malassez

An open-label, prospective phase I/II study evaluating the immunogenicity and safety of a ras peptide vaccine plus GM-CSF in patients with non-small cell lung cancer

Meyer, Ralf G.; Korn, Stephanie; Micke, Patrick; Becker, Kai et al.

Part of Lung Cancer, p. 88-94, 2007

• DOI for An open-label, prospective phase I/II study evaluating the immunogenicity and safety of a ras peptide vaccine plus GM-CSF in patients with non-small cell lung cancer

In Situ Identification of Genes Regulated Specifically in Fibroblasts of Human Basal Cell Carcinoma

Micke, Patrick; Kappert, Kai; Ohshima, Mitsuhiro; Sundquist, Christina et al.

Part of Journal of Investigative Dermatology, p. 1516-1523, 2007

• DOI for In Situ Identification of Genes Regulated Specifically in Fibroblasts of Human Basal Cell Carcinoma

Dynamic changes in the expression of DEP-1 and other PDGF receptor-antagonizing PTPs during onset and termination of neointima formation

Kappert, Kai; Paulsson, Janna; Sparwel, Jan; Leppänen, Olli et al.

Part of The FASEB Journal, p. 523-534, 2007

• DOI for Dynamic changes in the expression of DEP-1 and other PDGF receptor-antagonizing PTPs during onset and termination of neointima formation

Biobanking of fresh frozen tissue: RNA is stable in nonfixed surgical specimens.

Micke, Patrick; Ohshima, Mitsuhiro; Tahmasebpoor, Simin; Ren, Zhi-Ping et al.

Part of Lab Invest, p. 202-11, 2006

Cytokine profile in synovial fluid from patients with internal derangement of the temporomandibular joint: a preliminary study.

Matsumoto, K; Honda, K; Ohshima, M; Yamaguchi, Y et al.

Part of Dentomaxillofac Radiol, p. 432-41, 2006

Exploring the tumour environment: cancer-associated fibroblasts as targets in cancer therapy.

Micke, Patrick; Ostman, Arne

Part of Expert Opin Ther Targets, p. 1217-33, 2005

Laser-assisted cell microdissection using the PALM system.

Micke, Patrick; Östman, Arne; Lundeberg, Joakim; Ponten, Fredrik

Part of Methods Mol Biol, p. 151-66, 2005

A fluid cover medium provides superior morphology and preserves RNA integrity in tissue sections for laser microdissection and pressure catapulting

Micke, Patrick; Bjørnsen, Tone; Scheidl, Stefan; Strömberg, Sara et al.

Part of J Pathol, p. 130-8, 2004

Platelet-derived growth factor production by B16 melanoma cells leads to increased pericyte abundance in tumors and an associated increase in tumor growth rate

Furuhashi, Masao; Sjöblom, Tobias; Abramsson, Alexandra; Ellingsen, Jens et al.

Part of Cancer Research, p. 2725-2733, 2004

• DOI for Platelet-derived growth factor production by B16 melanoma cells leads to increased pericyte abundance in tumors and an associated increase in tumor growth rate

Zinc-based fixative improves preservation of genomic DNA and proteins in histoprocessing of human tissues.

Wester, Kenneth; Asplund, Anna; Bäckvall, Helena; Micke, Patrick et al.

Part of Lab Invest, p. 889-99, 2003

Characterization of c-kit expression in small cell lung cancer: prognostic and therapeutic implications

Micke, Patrick; Basrai, Maryam; Faldum, Andreas; Bittinger, Fernando et al.

Part of Clinical Cancer Research, p. 188-194, 2003

Downregulation of bradykinin B2 receptor in human fibroblasts during prolonged agonist exposure

Blaukat, Andree; Micke, Patrick; Kalatskaya, Irina; Faussner, Alexander et al.

Part of American Journal of Physiology. Heart and Circulatory Physiology, 2003

• DOI for Downregulation of bradykinin B2 receptor in human fibroblasts during prolonged agonist exposure

COX-2 expression and effects of celecoxib in addition to standard chemotherapy in advanced non-small cell lung cancer.

Gulyas, Miklos; Mattsson, Johanna Sofia Margareta; Lindgren, Andrea; Ek, Lars et al.

Diagnostic Value of Insulinoma-Associated Protein 1 (INSM1) and Comparison With Established Neuroendocrine Markers in Pulmonary Cancers: A Comprehensive Study and Review of the Literature

Staaf, Johan; Tran, Lena; Söderlund, Linnea; Nodin, Björn et al.

Part of Archives of Pathology & Laboratory Medicine, p. 1075-1085, 2020

• DOI for Diagnostic Value of Insulinoma-Associated Protein 1 (INSM1) and Comparison With Established Neuroendocrine Markers in Pulmonary Cancers: A Comprehensive Study and Review of the Literature

The Role of TGF- Signaling in Lung Cancer Associated with Idiopathic Pulmonary Fibrosis

Saito, Akira; Horie, Masafumi; Micke, Patrick; Nagase, Takahide

Part of International Journal of Molecular Sciences, 2018

• DOI for The Role of TGF- Signaling in Lung Cancer Associated with Idiopathic Pulmonary Fibrosis
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Immunohistochemistry-based prognostic biomarkers in NSCLC: novel findings on the road to clinical use?

Lindskog, Cecilia; Edlund, Karolina; Mattsson, Johanna Sofia Margareta; Micke, Patrick

Part of Expert Review of Molecular Diagnostics, p. 471-490, 2015

• DOI for Immunohistochemistry-based prognostic biomarkers in NSCLC: novel findings on the road to clinical use?

Prognostic relevance of cancer-associated fibroblasts in human cancer

Paulsson, Janna; Micke, Patrick

Part of Seminars in Cancer Biology, p. 61-68, 2014

• DOI for Prognostic relevance of cancer-associated fibroblasts in human cancer

Tumour-stroma interaction: cancer-associated fibroblasts as novel targets in anti-cancer therapy?

Micke, Patrick; Östman, Arne

Part of Lung Cancer, 2004

Isolated Channel Vision Transformers: From Single-Channel Pretraining to Multi-Channel Finetuning

Lian, Wenyi; Micke, Patrick; Lindblad, Joakim; Sladoje, Nataša

Part of 36th British Machine Vision Conference 2025, {BMVC} 2025, p. 1-14, 2025

Extending the immune phenotypes of lung cancer: Oasis in the desert

Backman, Max; La Fleur, Linnea; Kurppa, Pinja; Djureinovic, Dijana et al.

Antibody targeting of tumor associated macrophages in lung cancer remodel the tumor microenvironment and revives immune targeting of tumor cells

Sarhan, Dhifaf; La Fleur, Linnea; LI, Shuijie; Palano, Giorgia et al.

Plasma proteomic analysis in non-small cell lung cancer patients treated with PD1/PD-L1 blockade

Eltahir, Mohamed; Isaksson, Johan; Mattsson, Johanna Sofia Margareta; Kärre, Klas et al.

Highly selective in situ detection of mutant transcripts with gap-fill padlock probes and superRCA

Wang, Mengqi; Chen, Lei; Micke, Patrick; Strell, Carina et al.

From Cells to Survival: Hierarchical Analysis of Cell Inter-Relations in Multiplex Microscopy for Lung Cancer Prognosis

Edgren Schüllerqvist, Olle; Baumann, Jens; Lindblad, Joakim; Nordling, Love et al.

• DOI for From Cells to Survival: Hierarchical Analysis of Cell Inter-Relations in Multiplex Microscopy for Lung Cancer Prognosis
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