Anna-Karin Wikström
Professor at Department of Women's and Children's Health; Clinical Obstetrics
- E-mail:
- anna-karin.wikstrom@uu.se
- Visiting address:
- MTC-huset, Dag Hammarskjölds väg 14B, 1 tr
752 37 Uppsala - Postal address:
- Akademiska sjukhuset
751 85 UPPSALA
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Short presentation
Professor in obstetrics and gynecology, with a focus on research in obstetrics.
Biography
Born in Hudiksvall in 1965. Medical studies at Karolinska Institutet 1985-1991. Internship and resident training at Hudiksvalls hospital 1991-2000. Specialist in obstetrics and gynecology since 2001. Senior consultant since 2008. Dissertation in obstetrics and gynecology 2006, Uppsala University. Associate professor in obstetrics and gynecology 2011, Uppsala University. Post-doc at the unit of Clinical Epidemiology 2009-2011, Karolinska Institutet. Professor of Obstetrics and Gynecology Karolinska Institutet 2016-2017. Professor of Obstetrics and Gynecology Uppsala University since 2017.
Research
Research in obstetrics.
The main focus is preeclampsia.
Principal investigator for:
- IMPACT. Prediction of preeclampsia. Web-site: Impactstudie.se
- Up-MOST. Biobank of preeclampsia. Research of the maternal brain in preeclampsia.
Several register-based studies of preeclampsia.
Examples of other active projects:
- Pregnancy and reproduction in women with congenital heart defects
- Pregnancy in women with Myasthenia Gravis
- Pregnancy in women with Diabetes
- Pregnancy after donation of a kidney
- Alcohol and pregnancy
- Hypoxic Ischemic Encephalopahy of the newborn
Publications
Recent publications
- Heart disease in pregnancy and risk of pre-eclampsia (2024)
- Does Developing Interpregnancy Hypertension Affect the Recurrence Risk of Preeclampsia? (2024)
- Biomarkers associated with cardiovascular disease in women with spontaneous preterm birth (2024)
- Changing diagnostic criteria for gestational diabetes (CDC4G) in Sweden (2024)
- Metformin use and preeclampsia risk in women with diabetes (2024)
All publications
Articles
- Heart disease in pregnancy and risk of pre-eclampsia (2024)
- Does Developing Interpregnancy Hypertension Affect the Recurrence Risk of Preeclampsia? (2024)
- Biomarkers associated with cardiovascular disease in women with spontaneous preterm birth (2024)
- Changing diagnostic criteria for gestational diabetes (CDC4G) in Sweden (2024)
- Metformin use and preeclampsia risk in women with diabetes (2024)
- Breastfeeding in primiparous women with congenital heart disease (2024)
- Self-rated health in primiparous women with congenital heart disease before, during and after pregnancy (2024)
- Time to childbirth and assisted reproductive treatment in women with congenital heart disease (2024)
- Combined maternal central adiposity measures in relation to infant birth size (2024)
- Severe Perineal Lacerations in First Delivery (2024)
- Pregnancy outcomes for women with myasthenia gravis and their newborns (2024)
- Response to "More evidence is needed for the association between serum myasthenia gravis and adverse pregnancy, delivery and neonatal outcomes" (2024)
- Polycystic ovary syndrome and gestational diabetes mellitus association to pregnancy outcomes (2024)
- Inflammatory and cardiovascular markers in placenta following SARS-CoV-2 infection during pregnancy (2024)
- Pre-pregnancy participation and performance in world's largest cross-country ski race as a proxy for physical exercise and fitness, and perinatal outcomes (2023)
- Comparing the results from a Swedish pregnancy cohort using data from three automated placental growth factor immunoassay platforms intended for first-trimester preeclampsia prediction. (2023)
- Brain Vascular Dysfunction in Mothers and Their Children Exposed to Preeclampsia (2023)
- Study protocol (2023)
- Low-dose aspirin use in pregnancy and the risk of preterm birth (2023)
- Preterm birth and the mechanism of action of low-dose aspirin (2023)
- Association Between History of Adverse Pregnancy Outcomes and Coronary Artery Disease Assessed by Coronary Computed Tomography Angiography (2023)
- Early Mid-pregnancy Blood-Based Proteins as Possible Biomarkers of Increased Infant Birth Size in Sex-Stratified Analyses (2023)
- Maternal early mid-pregnancy adiponectin in relation to infant birth weight and the likelihood of being born large-for-gestational-age. (2023)
- Latent phase duration and associated outcomes (2023)
- Outcomes in children after mild neonatal hypoxic ischaemic encephalopathy (2023)
- Polycystic ovary syndrome and risk of pre‐eclampsia (2023)
- Alcohol exposure prior to pregnancy-does hazardous consumption affect placenta- and inflammatory-mediated pregnancy outcomes? A Swedish population-based cohort study (2022)
- Cerebral Biomarkers and Blood-Brain Barrier Integrity in Preeclampsia (2022)
- Gestational Diabetes Mellitus Risk in Pregnant Women With Systemic Lupus Erythematosus (2022)
- Low-Dose Aspirin for Preventing Birth of a Small-For-Gestational Age Neonate in a Subsequent Pregnancy (2022)
- Risk of pre-eclampsia after gastric bypass (2022)
- Reply to (2022)
- Elevated mid-pregnancy plasma levels of angiotensin-converting enzyme 2 in women prior to the development of preeclampsia. (2022)
- Maternal blood-based protein biomarkers in relation to abdominal fat distribution measured by ultrasound in early mid-pregnancy (2022)
- Associations between capillary glucose during pregnancy and childhood growth to the age of five (2022)
- Association Between Objectively Assessed Sleep and Depressive Symptoms During Pregnancy and Post-partum (2022)
- Dysregulation of vascular endothelial growth factor receptor 2 phosphorylation is associated with disruption of the blood-brain barrier and brain endothelial cell apoptosis induced by plasma from women with preeclampsia (2022)
- Negative childbirth experience-what matters most? (2022)
- Association of Maternal Preeclampsia With Offspring Risks of Ischemic Heart Disease and Stroke in Nordic Countries (2022)
- Clinical-pathological features in placentas of pregnancies with SARS-CoV-2 infection and adverse outcome (2022)
- Efficacy and safety of oral misoprostol versus transvaginal balloon catheter for labor induction (2021)
- Acute relaxation during pregnancy leads to a reduction in maternal electrodermal activity and self-reported stress levels (2021)
- Preeclampsia and Increased Permeability Over the Blood–Brain Barrier (2021)
- COVID-19 in Pregnancy and Early Childhood (COPE) (2021)
- Maternal lithium use and the risk of adverse pregnancy and neonatal outcomes (2021)
- Aspirin use during pregnancy and the risk of bleeding complications (2021)
- Time matters—a Swedish cohort study of labor duration and risk of uterine rupture (2021)
- Duration of labor among women with thromboembolic events (2021)
- Disruption of the Blood-Brain Barrier by Extracellular Vesicles From Preeclampsia Plasma and Hypoxic Placentae (2021)
- Associations of ultrasound estimated early mid pregnancy visceral and subcutaneous fat depths and early pregnancy BMI with adverse neonatal outcomes (2021)
- Swedish intrauterine growth reference ranges for estimated fetal weight (2021)
- The association between postpartum hemorrhage and postpartum depression (2021)
- Women's childbirth experiences in the Swedish Post-term Induction Study (SWEPIS) (2021)
- Ultrasound estimated subcutaneous and visceral adipose tissue thicknesses and risk of pre-eclampsia (2021)
- Waist circumference measurement for prediction of preeclampsia (2021)
- Routinely collected antenatal data for longitudinal prediction of preeclampsia in nulliparous women (2021)
- Maternal Hypertensive Disorders in Pregnant Women With Systemic Lupus Erythematosus and Future Cardiovascular Outcomes (2021)
- Evidence of under-reporting of early-onset preeclampsia using register data (2021)
- Study protocol (2021)
- Hypoxic ischemic encephalopathy in offspring of immigrant women in Sweden (2021)
- Pregnancy outcome in women with polycystic ovary syndrome in relation to second-trimester testosterone levels (2021)
- Polycystic ovary syndrome and risk of stillbirth (2021)
- Polycystic ovary syndrome and extremely preterm birth (2021)
- Self‐rated health before pregnancy and adverse birth outcomes in Sweden (2021)
- Induction of labour at 41 weeks or expectant management until 42 weeks (2020)
- Multi-Fetal Pregnancy, Preeclampsia, and Long-Term Cardiovascular Disease (2020)
- Study for Improving Maternal Pregnancy And Child ouTcomes (IMPACT) (2020)
- Epidural analgesia during Childbirth and Postpartum depressive symptoms (2020)
- Accelerated fetal growth in early pregnancy and risk of preterm birth (2020)
- Placental location and risk of retained placenta in women with a previous cesarean section (2020)
- Duration of labor among women with hypertensive disorders of pregnancy; A Swedish register cohort study (2020)
- Association of maternal central adiposity measured by ultrasound in early mid pregnancy with infant birth size (2020)
- Pregnancy in metabolic healthy and unhealthy obese women (2020)
- Interpregnancy weight change and recurrence of gestational diabetes mellitus (2020)
- Induction of Labour at 41 Weeks Versus Expectant Management and Induction of Labour at 42 Weeks (SWEdish Post-Term Induction Study, SWEPIS) (2020)
- Factors associated with re-initiation of antidepressant treatment following discontinuation during pregnancy (2020)
- Delivery outcome after trial of labor in nulliparous women 40 years or older-A nationwide population-based study (2019)
- Investigating the association between neuroticism and adverse obstetric and neonatal outcomes (2019)
- Neuroticism is associated with higher antenatal care utilization in obstetric low-risk women (2019)
- Investigating Maternal Brain Alterations in Preeclampsia (2019)
- Changing diagnostic criteria for gestational diabetes in Sweden-a stepped wedge national cluster randomised controlled trial-the CDC4G study protocol (2019)
- Placental location and pregnancy outcomes in nulliparous women (2019)
- Elevated diastolic blood pressure until mid-gestation is associated with preeclampsia and small-for-gestational-age birth (2019)
- Proton Pump Inhibitors and Preeclampsia Risk Among 157 720 Women (2019)
- Neighborhood deprivation and adverse perinatal outcomes in Sweden (2019)
- Growth patterns during early childhood in children born small for gestational age and moderate preterm (2019)
- Postnatal growth in children born small for gestational age with and without smoking mother (2019)
- Maternal body mass index moderates antenatal depression effects on infant birthweight (2019)
- The Swedish Neonatal Quality Register - contents, completeness and validity (2019)
- Clinical risk assessment in early pregnancy for preeclampsia in nulliparous women (2019)
- Preterm Delivery Phenotypes in Systemic Lupus Erythematosus Pregnancies (2019)
- Association of Attention-Deficit/Hyperactivity Disorder With Teenage Birth Among Women and Girls in Sweden (2019)
- Pregnancy and neonatal complications in women with polycystic ovary syndrome in relation to second-trimester anti-Müllerian hormone levels (2019)
- Prenatal exposures and birth indices, and subsequent risk of polycystic ovary syndrome (2019)
- Induction of labour at 41 weeks versus expectant management and induction of labour at 42 weeks (SWEdish Post-term Induction Study, SWEPIS) (2019)
- Delineating the association between mode of delivery and postpartum depression symptoms (2018)
- The inherited risk of retained placenta (2018)
- Prenatal exposure to preeclampsia is associated with accelerated height gain in early childhood (2018)
- Pregnancy Weight Gain Before Diagnosis and Risk of Preeclampsia (2018)
- Obstetric emergencies as antecedents to neonatal hypoxic ischemic encephalopathy, does parity matter? (2018)
- Antepartum risk factors for moderate to severe neonatal hypoxic ischemic encephalopathy (2018)
- Assessment of cerebral perfusion and edema in preeclampsia with intravoxel incoherent motion MRI (2018)
- Cerebral osmolytes and plasma osmolality in pregnancy and preeclampsia (2018)
- The Swedish Pregnancy Register - for quality of care improvement and research (2018)
- Serum Pentraxin 3 is associated with signs of arterial alteration in women with preeclampsia. (2017)
- Association between angiogenic factors and signs of arterial aging in women with pre-eclampsia (2017)
- Early second-trimester plasma levels of NT-proBNP in women who subsequently develop early-onset preeclampsia (2017)
- Chronic hypertension in women after perinatal exposure to preeclampsia, being born small for gestational age or preterm (2017)
- Opium use during pregnancy and risk of preterm delivery (2017)
- Induction of labor versus expectant management of large-for-gestational-age infants in nulliparous women (2017)
- Cerebral Magnesium Levels in Preeclampsia; A Phosphorus Magnetic Resonance Spectroscopy Study (2017)
- Association Between Pregnancy and Perinatal Outcomes Among Women With Epilepsy (2017)
- Early-onset Preeclampsia in Lupus Pregnancy. (2017)
- Preterm Delivery Phenotypes in SLE Pregnancies (2017)
- Slow fetal growth between first and early second trimester ultrasound scans and risk of small for gestational age (SGA) birth. (2017)
- Accelerated fetal growth in early pregnancy and risk of severe large-for-gestational-age and macrosomic infant (2017)
- Cerebral Biomarkers in Women With Preeclampsia Are Still Elevated 1 Year Postpartum (2016)
- Maternal tobacco use and extremely premature birth - a population-based cohort study (2016)
- Placental abruption and long-term maternal cardiovascular disease mortality (2016)
- Delineating the Association between Heavy Postpartum Haemorrhage and Postpartum Depression (2016)
- Study protocol of SWEPIS a Swedish multicentre register based randomised controlled trial to compare induction of labour at 41 completed gestational weeks versus expectant management and induction at 42 completed gestational weeks (2016)
- High Maternal Body Mass Index in Early Pregnancy and Risks of Stillbirth and Infant Mortality-A Population-Based Sibling Study in Sweden (2016)
- Pregnancy hypertensive disease and risk of dementia and cardiovascular disease in women aged 65 years or older (2016)
- Maternal overweight and obesity and risk of pre-eclampsia in women with type 1 diabetes or type 2 diabetes (2016)
- Prolonged second stage of labour, maternal infectious disease, urinary retention and other complications in the early postpartum period (2016)
- Prehypertension in Pregnancy and Risks of Small for Gestational Age Infant and Stillbirth (2016)
- Iodine deficiency in a study population of pregnant women in Sweden (2015)
- Pregnancy and perinatal outcomes in women with polycystic ovary syndrome and twin births (2015)
- Consanguineous marriage, prepregnancy maternal characteristics and stillbirth risk (2015)
- Does Use of Low-Molecular-Weight Heparin during Pregnancy Influence the Risk of Prolonged Labor (2015)
- MRI estimated placental perfusion in fetal growth assessment (2015)
- Evaluation of a Plasma hCG Method for Point of Care Testing with the Aim of Shortening Test-Turnaround-Times (2015)
- Thicknesses of individual layers of artery wall indicate increased cardiovascular risk in severe pre-eclampsia (2014)
- Influence of Snuff and Smoking Habits in Early Pregnancy on Risks for Stillbirth and Early Neonatal Mortality (2014)
- Risk of retained placenta in women previously delivered by caesarean section (2014)
- Plasma Levels of S100B in Preeclampsia and Association With Possible Central Nervous System Effects (2014)
- Retained placenta is associated with pre-eclampsia, stillbirth, giving birth to a small-for-gestational-age infant, and spontaneous preterm birth (2014)
- Targeted Thyroid Testing During Pregnancy in Clinical Practice (2014)
- Risk of placental dysfunction disorders after prior miscarriages (2014)
- Maternal Snuff Use and Smoking and the Risk of Oral Cleft Malformations - A Population-Based Cohort Study (2014)
- Placental Expression of proBNP/NT-proBNP and Plasma Levels of NT-proBNP in Early- and Late-Onset Preeclampsia (2014)
- Loss of a close family member the year before or during pregnancy and the risk of placental abruption (2014)
- Experience of fetal scalp blood sampling during labor (2014)
- Placental perfusion in normal pregnancy and early and late preeclampsia (2014)
- In vivo(31)P-MR spectroscopy in normal pregnancy, early and late preeclampsia (2014)
- Artery Wall Layer Dimensions during Normal Pregnancy (2013)
- Individual Common Carotid Artery Wall Layer Dimensions, but Not Carotid Intima-Media Thickness, Indicate Increased Cardiovascular Risk in Women With Preeclampsia (2013)
- Changes in snuff and smoking habits in Swedish pregnant women and risk for small for gestational age births (2013)
- Plasma Levels of S100B in Women with Preeclampsia (2013)
- Hyperemesis gravidarum and risks of placental dysfunction disorders (2013)
- Maternal Obesity and Risk of Preterm Delivery EDITORIAL COMMENT (2013)
- Maternal Obesity and Risk of Preterm Delivery (2013)
- Thyroid Testing and Management of Hypothyroidism During Pregnancy (2013)
- Elective induction of labor and the risk of cesarean section in low-risk parous women (2013)
- PP015. Plasma levels and placental expression of BNP/NT-proBNP in early and late onset preeclampsia (2013)
- Psychosocial Stress Related to the Loss of a Close Relative the Year Before or During Pregnancy and Risk of Preeclampsia (2013)
- Changes in the Artery Wall Layer Dimensions in Women with Preeclampsia (2012)
- Cause-specific infant mortality in a population-based Swedish study of term and post-term births (2012)
- Influence of smoking and snuff cessation on risk of preterm birth (2012)
- Prediction of Preeclampsia by Combining Serum Histidine-Rich Glycoprotein and Uterine Artery Doppler (2012)
- High birth weight and obesity (2012)
- Phosphodiesterase 8B gene polymorphism in women with recurrent miscarriage (2012)
- Gene expression profiling of placentae from women with early- and late-onset pre-eclampsia (2012)
- From infancy to pregnancy (2012)
- Interpregnancy Change in Smoking Habits and Risk of Preeclampsia (2012)
- Labour dystocia - risk of recurrence and instrumental delivery in following labour (2012)
- Maternal Body Mass Index, Height, and Risks of Preeclampsia (2012)
- Plasma levels of S100B during pregnancy in women developing pre-eclampsia (2012)
- The Paternal Role in Preeclampsia and Giving Birth to Small for Gestational Age Infant. (2012)
- The paternal role in pre-eclampsia and giving birth to a small for gestational age infant (2012)
- Relationship of Maternal Snuff Use and Cigarette Smoking With Neonatal Apnea (2011)
- Evaluation of the discrepancy between pH and lactate in combined fetal scalp blood sampling (2011)
- Previous preeclampsia and risks of adverse outcomes in subsequent nonpreeclamptic pregnancies (2011)
- Snus under är inte ett riskfritt alternativ till rökning [Snuff during pregnancy no risk-free alternative to smoking] (2011)
- Recurrence of placental dysfunction disorders across generations (2011)
- Fibrinogen and histidine-rich glycoprotein in early-onset preeclampsia (2010)
- Effect of Swedish snuff (snus) on preterm birth (2010)
- Maternal Use of Swedish Snuff (Snus) and Risk of Stillbirth (2010)
- Tobacco Use During Pregnancy and Preeclampsia Risk (2010)
- Increased circulating levels of the antiangiogenic factor endostatin in early-onset but not late-onset preeclampsia (2009)
- Evidence of increased oxidative stress and a change in the plasminogen activator inhibitor (PAI)-1 to PAI-2 ratio in early-onset but not late-onset preeclampsia (2009)
- Early postpartum changes in circulating pro- and anti-angiogenic factors in early-onset and late-onset pre-eclampsia (2008)
- Placental growth factor and soluble fms-like tyrosine kinase-1 in early-onset and late-onset preeclampsia (2007)
- Random albumin/creatinine ratio for quantification of proteinuria in manifest pre-eclampsia - Reply (2007)
- Random albumin/creatinine ratio for quantification of proteinuria in manifest pre-eclampsia - Reply (2007)
- Neuroticism is not independently associated with adverse obstetric or neonatal outcomes
- Biomarkers for cardiovascular disease in women with spontaneous preterm birth – A case control study
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