Helgi Schiöth

Genetic GHSR deficiency and LEAP2 treatment enhance the glucose-lowering effects of liraglutide in male mice in a metabolic state-dependent manner

Cassano, Daniela A.; Fernandez, Gimena; Cornejo, Maria P.; Sheybani-Deloui, Sepideh et al.

Part of Life Sciences, 2026

• DOI for Genetic GHSR deficiency and LEAP2 treatment enhance the glucose-lowering effects of liraglutide in male mice in a metabolic state-dependent manner
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LEAP2 mediates long-term inhibition of orexigenic neurons of the hypothalamus in mice

Giovanini, Lucia; Cornejo, Maria P.; Gomez, Ivana M.; Wanionok, Nahuel et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, 2026

• DOI for LEAP2 mediates long-term inhibition of orexigenic neurons of the hypothalamus in mice

Metabolomics workbench: data-driven classification and correlation analysis between metabolite classes, biomarkers, and drugs

Khandokhin, Mikhail M.; Sokolov, Aleksandr; Oskolkov, Nikolay; Fredriksson, Robert et al.

Part of Briefings in Bioinformatics, 2026

• DOI for Metabolomics workbench: data-driven classification and correlation analysis between metabolite classes, biomarkers, and drugs
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CELF2 Is a Tumor Suppressor That Modulates SLC7A11 and Promotes Ferroptosis in Stomach Adenocarcinoma

Zhang, Shoucai; Liu, Shichao; Zhang, Zeyu; Liu, Yingjie et al.

Part of Molecular Cancer Research, p. 809-820, 2026

• DOI for CELF2 Is a Tumor Suppressor That Modulates SLC7A11 and Promotes Ferroptosis in Stomach Adenocarcinoma

Milk and infant plasma hormone concentrations predict sweet and fat taste acceptance and later food intake

Kruger, Ana Luz; Malpeli, Agustina; Sala, Marisa; Casado, Carla et al.

Part of Journal of neuroendocrinology, 2026

• DOI for Milk and infant plasma hormone concentrations predict sweet and fat taste acceptance and later food intake
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Genetic GHSR deficiency and LEAP2 treatment enhance the glucose-lowering effects of liraglutide in male mice in a metabolic state-dependent manner

Cassano, Daniela A.; Fernandez, Gimena; Cornejo, Maria P.; Sheybani-Deloui, Sepideh et al.

Part of Life Sciences, 2026

• DOI for Genetic GHSR deficiency and LEAP2 treatment enhance the glucose-lowering effects of liraglutide in male mice in a metabolic state-dependent manner
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LEAP2 mediates long-term inhibition of orexigenic neurons of the hypothalamus in mice

Giovanini, Lucia; Cornejo, Maria P.; Gomez, Ivana M.; Wanionok, Nahuel et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, 2026

• DOI for LEAP2 mediates long-term inhibition of orexigenic neurons of the hypothalamus in mice

Metabolomics workbench: data-driven classification and correlation analysis between metabolite classes, biomarkers, and drugs

Khandokhin, Mikhail M.; Sokolov, Aleksandr; Oskolkov, Nikolay; Fredriksson, Robert et al.

Part of Briefings in Bioinformatics, 2026

• DOI for Metabolomics workbench: data-driven classification and correlation analysis between metabolite classes, biomarkers, and drugs
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CELF2 Is a Tumor Suppressor That Modulates SLC7A11 and Promotes Ferroptosis in Stomach Adenocarcinoma

Zhang, Shoucai; Liu, Shichao; Zhang, Zeyu; Liu, Yingjie et al.

Part of Molecular Cancer Research, p. 809-820, 2026

• DOI for CELF2 Is a Tumor Suppressor That Modulates SLC7A11 and Promotes Ferroptosis in Stomach Adenocarcinoma

Milk and infant plasma hormone concentrations predict sweet and fat taste acceptance and later food intake

Kruger, Ana Luz; Malpeli, Agustina; Sala, Marisa; Casado, Carla et al.

Part of Journal of neuroendocrinology, 2026

• DOI for Milk and infant plasma hormone concentrations predict sweet and fat taste acceptance and later food intake
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Parental support moderates the interaction of COMT and BDNF genotypes with early life adversity on problem gambling severity index scores among young adults

Mohamed, Mohamed S.; Rukh, Gull; Bendre, Megha; Vadlin, Sofia et al.

Part of Psychiatry Research, 2026

• DOI for Parental support moderates the interaction of COMT and BDNF genotypes with early life adversity on problem gambling severity index scores among young adults
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Candidate biomarkers in narcolepsy in H1N1-vaccinated cohorts: A proteomic and transcriptomic study

Lafta, Muataz S.; Sokolov, Aleksandr V.; Kitok, Mattis; Berntsson, Shala G. et al.

Part of Sleep Medicine, 2026

• DOI for Candidate biomarkers in narcolepsy in H1N1-vaccinated cohorts: A proteomic and transcriptomic study

Pariset: A primary dataset for therapeutic algal peptides focusing on antihypertensive, antioxidative, antibacterial, antihyperglycemic, and anticancer activities

Karimi, Isaac; Olfati, Parisa; Yousofvand, Namdar; Mohammed, Layth Jasim et al.

Part of Electronic Journal of Biotechnology, 2026

• DOI for Pariset: A primary dataset for therapeutic algal peptides focusing on antihypertensive, antioxidative, antibacterial, antihyperglycemic, and anticancer activities
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Role of genetic polymorphisms on opioid safety and efficacy in cancer pain: A systematic review and meta-analysis

Akan, Mikail; Panina, Aleksandra; Khandokhin, Mikhail; Mohammad, Salahuddin et al.

Part of European Journal of Pharmacology, 2026

• DOI for Role of genetic polymorphisms on opioid safety and efficacy in cancer pain: A systematic review and meta-analysis
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Transcriptomic meta-analysis identifies dysregulated pathways and potential therapeutic targets in Vestibular Schwannoma

Altinalan, Ebrar; Panina, Aleksandra; Fredriksson, Robert; Sakul, Ayse Arzu et al.

Part of PLOS ONE, 2026

• DOI for Transcriptomic meta-analysis identifies dysregulated pathways and potential therapeutic targets in Vestibular Schwannoma
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Development and validation of a prediction model for lymph node metastasis based on molecular typing in clinically early-stage endometrial carcinoma

Han, Qiuyue; Jiang, Quanhong; Xu, Jiaqi; Zhang, Yuan et al.

Part of Journal of Gynecologic Oncology, 2026

• DOI for Development and validation of a prediction model for lymph node metastasis based on molecular typing in clinically early-stage endometrial carcinoma
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Immunothrombosis in hospitalized COVID-19 patients identified by multiomics profiling and linked to postacute complications

Ansone, Laura; Pelcmane, Liva; Briviba, Monta; Saksis, Rihards et al.

Part of iScience, 2026

• DOI for Immunothrombosis in hospitalized COVID-19 patients identified by multiomics profiling and linked to postacute complications
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The RASA2/RASA3 ortholog RasGAP1 modulates obesity-linked phenotypes and is associated with leptin-analog signaling in Drosophila

Moulin, Thiago C.; Williams, Michael J.; Schiöth, Helgi B.

Part of Frontiers in Endocrinology, 2026

• DOI for The RASA2/RASA3 ortholog RasGAP1 modulates obesity-linked phenotypes and is associated with leptin-analog signaling in Drosophila
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Associations of PYY, GLP-1 and LEAP2 with changes in feeding-related cognition, body weight and glucose homeostasis after bariatric surgery in non-diabetic women

Andreoli, María Florencia; De Francesco, Pablo N.; Zhou, Wei; Titova, Olga et al.

Part of Journal of neuroendocrinology, 2026

• DOI for Associations of PYY, GLP-1 and LEAP2 with changes in feeding-related cognition, body weight and glucose homeostasis after bariatric surgery in non-diabetic women
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GC-IMS-based analysis of serum volatile organic compounds for diagnosis of gastric cancer

Zhao, Yuxiao; Xin, Yueming; Mao, Mai; Zheng, Xin et al.

Part of Scientific Reports, 2026

• DOI for GC-IMS-based analysis of serum volatile organic compounds for diagnosis of gastric cancer
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Integrative transcriptomic meta-analysis reveals immune, synaptic, and non-coding RNA dysregulation in bipolar disorder across brain and blood

Panina, Aleksandra; Sokolov, Aleksandr V.; Jonsson, Jörgen; Fredriksson, Robert et al.

Part of Neurobiology of Disease, 2026

• DOI for Integrative transcriptomic meta-analysis reveals immune, synaptic, and non-coding RNA dysregulation in bipolar disorder across brain and blood
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Meta-analysis of blood metabolomics reveals dysregulated amino acid, neurotransmitter, and energy pathways in depression

Panina, Aleksandra; Sokolov, Aleksandr V.; Khandokhin, Mikhail M.; Oskolkov, Nikolay et al.

Part of Progress in Neuro-psychopharmacology and Biological Psychiatry, 2026

• DOI for Meta-analysis of blood metabolomics reveals dysregulated amino acid, neurotransmitter, and energy pathways in depression
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Trends in drug discovery for carbonic anhydrases: FDA approvals, clinical trials, molecular functions, and therapeutic potential

Kojis, Tautvydas; Schiöth, Helgi; Baranauskiene, Lina; Matulis, Daumantas

Part of Pharmacological Research, 2026

• DOI for Trends in drug discovery for carbonic anhydrases: FDA approvals, clinical trials, molecular functions, and therapeutic potential
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Conned by the enemy: the entomopathogenic fungus Metarhizium anisopliae lures and kills Drosophila suzukii

Farid, Ibrahim M.; Ndlela, Shepard; Becher, Paul G.; Weldon, Christopher W. et al.

Part of Pest Management Science, p. 4595-4606, 2026

• DOI for Conned by the enemy: the entomopathogenic fungus Metarhizium anisopliae lures and kills Drosophila suzukii
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Identification of suicide brain transcriptomic signatures using meta-analysis of multiple cohorts

Sokolov, Aleksandr V.; Lafta, Muataz; Jokinen, Jussi; Schiöth, Helgi

Part of Translational Psychiatry, 2026

• DOI for Identification of suicide brain transcriptomic signatures using meta-analysis of multiple cohorts
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Naringin nanoparticles alleviate RA-ILD pulmonary fibrosis by targeting 14-3-3ζ to inhibit LYVE1⁺macrophages TGF-β1 secretion

Li, Xiaohan; Wang, Jianzhu; Zhang, Xiaoyu; Wang, Xilong et al.

Part of Materials Today Bio, 2026

• DOI for Naringin nanoparticles alleviate RA-ILD pulmonary fibrosis by targeting 14-3-3ζ to inhibit LYVE1⁺macrophages TGF-β1 secretion
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The grateful eight: perspectives on higher education affordances and tensions and didactics role in enhancing learning experiences towards sustainability

Nordén, Birgitta; Ulvenblad, Pia; Mäenpää, Antti; Vogopoulou, Areti et al.

Part of Frontiers in Education, 2026

• DOI for The grateful eight: perspectives on higher education affordances and tensions and didactics role in enhancing learning experiences towards sustainability
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Conserved NT5C2 links context-specific behaviors with psychiatric and metabolic risk

Moulin, Thiago; Aldavero-Munoz, Ivan; Williams, Michael J.; Schiöth, Helgi

Part of Behavioral and Brain Functions, 2026

• DOI for Conserved NT5C2 links context-specific behaviors with psychiatric and metabolic risk
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Enriched and deficient omega-3 PUFA exposure from gestation to adulthood modulates anxiety-related behavior and stress- and neuroplasticity-related brain gene expression in mice

Bianconi, Santiago; Cantarelli, Veronica I.; Almonacid, Juan E. Robledo; Zingerling, Emilio et al.

Part of Progress in Neuro-psychopharmacology and Biological Psychiatry, 2026

• DOI for Enriched and deficient omega-3 PUFA exposure from gestation to adulthood modulates anxiety-related behavior and stress- and neuroplasticity-related brain gene expression in mice
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Identification and validation of depression-associated genetic variants in the UK Biobank cohort with transcriptome and DNA methylation analyses in independent cohorts

Lafta, Muataz; Sokolov, Aleksandr V.; Rukh, Gull; Schiöth, Helgi

Part of Heliyon, 2025

• DOI for Identification and validation of depression-associated genetic variants in the UK Biobank cohort with transcriptome and DNA methylation analyses in independent cohorts
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Extensive analysis of pollutant interactions: Identification of deleterious synergistic effects at environmentally relevant dose levels using Drosophila and mammalian cells

Lagunas-Rangel, Francisco Alejandro; Åberg, Martin; Liao, Sifang; Espinelli-Amorim, Felippe et al.

Part of Science of the Total Environment, 2025

• DOI for Extensive analysis of pollutant interactions: Identification of deleterious synergistic effects at environmentally relevant dose levels using Drosophila and mammalian cells
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Establishment and verification of a prognostic signature associated with fatty acid metabolism in endometrial cancer

Peng, Lu; Sun, Rui; Hao, Tingting; Mu, Yulong et al.

Part of Molecular Medicine Reports, 2025

• DOI for Establishment and verification of a prognostic signature associated with fatty acid metabolism in endometrial cancer
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Intracerebral Administration of Hydrogen Sulfide Impairs Bioenergetics, Redox Status and Mitochondrial Quality Control in Rat Striatum

Marcuzzo, Manuela Bianchin; de Andrade Silveira, Josyane; Pinheiro, Camila Vieira; da Rosa, Jaqueline Santana et al.

Part of Neurotoxicity research, 2025

• DOI for Intracerebral Administration of Hydrogen Sulfide Impairs Bioenergetics, Redox Status and Mitochondrial Quality Control in Rat Striatum

Statin drugs and lipid modulation: Mechanistic basis considering lipid rafts, kinase signaling, myopathy, and cancer

Karthikeyan, Suditi; Somasundaram, Poornima; Karimi, Isaac; Lagunas-Rangel, Francisco Alejandro et al.

Part of Pharmacological Research, 2025

• DOI for Statin drugs and lipid modulation: Mechanistic basis considering lipid rafts, kinase signaling, myopathy, and cancer
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Statin Use Is Associated With a Decline in Muscle Function and Mass Over Time, Irrespective of Statin Pharmacogenomic Score

Gentreau, Mélissa; Sakr, Mahitab; Mohammad, Salahuddin; Alsehli, Ahmed M. et al.

Part of Journal of Cachexia, Sarcopenia and Muscle, 2025

• DOI for Statin Use Is Associated With a Decline in Muscle Function and Mass Over Time, Irrespective of Statin Pharmacogenomic Score
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The anti-aging potential of antihypertensive peptides of Pariset, a dataset of algal peptides

Karimi, Isaac; Olfati, Parisa; Mohammed, Layth Jasim; Kadhim Tarrad, Jawad et al.

Part of Frontiers in Aging, 2025

• DOI for The anti-aging potential of antihypertensive peptides of Pariset, a dataset of algal peptides
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Revisiting Ego Depletion: Evidence from Multi-Lab Collaborations

Dang, Junhua; Xiao, Shanshan; Mao, Lihua; Liu, Xiaoping et al.

Part of JOURNAL OF PACIFIC RIM PSYCHOLOGY, 2025

• DOI for Revisiting Ego Depletion: Evidence from Multi-Lab Collaborations
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Multi-omics profiling identifies M1 macrophage polarization-associated biomarkers in hepatitis B virus-related acute-on-chronic liver failure

Sun, Chengxi; Li, Cheng; Hong, Jianguo; Lv, Wencheng et al.

Part of Frontiers in Microbiology, 2025

• DOI for Multi-omics profiling identifies M1 macrophage polarization-associated biomarkers in hepatitis B virus-related acute-on-chronic liver failure
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Plasma LEAP2 concentration is associated with energy intake and postprandial insulin increase depending on meal size but not weight status in men

Andreoli, María Florencia; De Francesco, Pablo N.; Titova, Olga E; Perello, Mario et al.

Part of Diabetes, obesity and metabolism, p. 4427-4435, 2025

• DOI for Plasma LEAP2 concentration is associated with energy intake and postprandial insulin increase depending on meal size but not weight status in men
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Integrative proteomic analysis provides novel therapeutic insights for etiological subtypes of diabetes

Wei, Jiahe; Wu, Hanzhang; Wang, Ningjian; Zhu, Jiahao et al.

Part of Diabetes, obesity and metabolism, 2025

• DOI for Integrative proteomic analysis provides novel therapeutic insights for etiological subtypes of diabetes
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Plasma LEAP2 concentration is associated with attention and cognitive responses to low-calorie food cues in men depending on body weight status

Andreoli, María Florencia; De Francesco, Pablo N.; Titova, Olga E; Perello, Mario et al.

Part of Physiology and Behavior, 2025

• DOI for Plasma LEAP2 concentration is associated with attention and cognitive responses to low-calorie food cues in men depending on body weight status
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Statins regulate kinase signaling by causing changes in phosphorylation, rather than through changes in gene expression or direct inhibition: evidence in colorectal cancer

Lagunas-Rangel, Francisco Alejandro; Jonsson, Jörgen; Jackevica, Ludmila; Fredriksson, Robert et al.

Part of Frontiers in Pharmacology, 2025

• DOI for Statins regulate kinase signaling by causing changes in phosphorylation, rather than through changes in gene expression or direct inhibition: evidence in colorectal cancer
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AgRP neuron activity enhances reward-related consummatory behaviors during energy deficit in mice

Cassano, Daniela A.; Barrile, Franco; Reynaldo, Mirta; Fernandez, Gimena et al.

Part of Communications Biology, 2025

• DOI for AgRP neuron activity enhances reward-related consummatory behaviors during energy deficit in mice
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Liraglutide induces enhanced suppression of food intake in mice lacking the growth hormone secretagogue receptor

Cassano, Daniela A.; Aguggia, Julieta; Giovanini, Lucia; Heredia, Florencia et al.

Part of Molecular and Cellular Endocrinology, 2025

• DOI for Liraglutide induces enhanced suppression of food intake in mice lacking the growth hormone secretagogue receptor
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The interplay of genetics and fatty acid metabolism: exploring their impact on metabolic syndrome in Swedish men

Oskarsdottir, Harpa; Palsson, Arnar; Olafsdottir, Erla B.; Giedraitis, Vilmantas et al.

Part of Nutrition Journal, 2025

• DOI for The interplay of genetics and fatty acid metabolism: exploring their impact on metabolic syndrome in Swedish men
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A global survey on the associations between the lockdown group, free memory recall and emotional responses during the COVID-19 lockdown

Oyejide, Aderemi O.; Besharati, Sahba N.; Alcock, Stephanie; Schiöth, Helgi et al.

Part of Scientific Reports, 2025

• DOI for A global survey on the associations between the lockdown group, free memory recall and emotional responses during the COVID-19 lockdown
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Carbonic anhydrase IX inhibition as a path to treat neuroblastoma

Petrosiute, Agne; Zaksauskas, Audrius; Luciunaite, Asta; Petrauskas, Vytautas et al.

Part of British Journal of Pharmacology, p. 1610-1629, 2025

• DOI for Carbonic anhydrase IX inhibition as a path to treat neuroblastoma

Synthesis, characterization, and computational evaluation of some synthesized xanthone derivatives: focus on kinase target network and biomedical properties

Muslim, Wisam Taher; Mohammad, Layth Jasim; Naji, Munaf M.; Karimi, Isaac et al.

Part of Frontiers in Pharmacology, 2025

• DOI for Synthesis, characterization, and computational evaluation of some synthesized xanthone derivatives: focus on kinase target network and biomedical properties
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Targeting platinum-resistant ovarian cancer by disrupting histone and RAD51 lactylation

Sun, Chenggong; Li, Xiao; Teng, Qiuli; Liu, Xihan et al.

Part of Theranostics, p. 3055-3075, 2025

• DOI for Targeting platinum-resistant ovarian cancer by disrupting histone and RAD51 lactylation

New label-free serum exosomes detection method based on hierarchical SERS substrate for diagnosis of pancreatic cancer using AI

Wang, Hu; Li, Yanru; Chen, Shuai; Yan, Jie et al.

Part of Sensors and actuators. B, Chemical, 2025

• DOI for New label-free serum exosomes detection method based on hierarchical SERS substrate for diagnosis of pancreatic cancer using AI
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Ketamine and Esketamine in Clinical Trials: FDA‐Approved and Emerging Indications, Trial Trends With Putative Mechanistic Explanations

Vekhova, Ksenia A.; Namiot, Eugenia D.; Jonsson, Jörgen; Schiöth, Helgi

Part of Clinical Pharmacology and Therapeutics, p. 374-386, 2025

• DOI for Ketamine and Esketamine in Clinical Trials: FDA‐Approved and Emerging Indications, Trial Trends With Putative Mechanistic Explanations
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GPCR drug discovery: new agents, targets and indications

Lorente, Javier Sánchez; Sokolov, Aleksandr V.; Ferguson, Gavin; Schiöth, Helgi et al.

Part of Nature reviews. Drug discovery, 2025

• DOI for GPCR drug discovery: new agents, targets and indications

Migraine and its major subtypes: with and without aura are associated with polygenic scores for autism

Mohammad, Salahuddin; Bussu, Giorgia; Rukh, Gull; Schiöth, Helgi B. et al.

Part of Cephalalgia, p. 1-12, 2025

• DOI for Migraine and its major subtypes: with and without aura are associated with polygenic scores for autism
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Associations between genetic variations in oxytocin pathway genes and hippocampal volume: Insights from the UK Biobank

Xiao, Shanshan; Ebner, Natalie C.; Dang, Junhua; Rukh, Gull et al.

Part of Cortex, p. 211-219, 2025

• DOI for Associations between genetic variations in oxytocin pathway genes and hippocampal volume: Insights from the UK Biobank
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Perfluorooctanoic acid induces transgenerational modifications in reproduction, metabolism, locomotor activity, and sleep behavior in Drosophila melanogaster and deleterious effects in human cancer cells

Liao, Sifang; Sun, Chengxi; Lagunas-Rangel, Francisco Alejandro; Liu, Wen et al.

Part of Science of the Total Environment, 2024

• DOI for Perfluorooctanoic acid induces transgenerational modifications in reproduction, metabolism, locomotor activity, and sleep behavior in Drosophila melanogaster and deleterious effects in human cancer cells
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Targeted anticancer pre-vinylsulfone covalent inhibitors of carbonic anhydrase IX

Vaškevičius, Aivaras; Baronas, Denis; Leitans, Janis; Kvietkauskaitė, Agnė et al.

Part of eLIFE, 2024

• DOI for Targeted anticancer pre-vinylsulfone covalent inhibitors of carbonic anhydrase IX
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Pre-prandial plasma liver-expressed antimicrobial peptide 2 (LEAP2) concentration in humans is inversely associated with hunger sensation in a ghrelin independent manner

Andreoli, María Florencia; Fittipaldi, Antonela S; Castrogiovanni, Daniel; De Francesco, Pablo N et al.

Part of European Journal of Nutrition, p. 751-762, 2024

• DOI for Pre-prandial plasma liver-expressed antimicrobial peptide 2 (LEAP2) concentration in humans is inversely associated with hunger sensation in a ghrelin independent manner

Differential change in alcohol consumption during the COVID-19 pandemic: the role of loneliness, socialization, and mental well-being

Mohamed, Mohamed S.; Rukh, Gull; Vadlin, Sofia; Olofsdotter, Susanne et al.

Part of Frontiers in Psychiatry, 2024

• DOI for Differential change in alcohol consumption during the COVID-19 pandemic: the role of loneliness, socialization, and mental well-being
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Differentiating the relationships between traditional and new media use and sleep quality during the COVID-19 pandemic: roles of psychological distress and age

Xu, Tong; Zhu, Dongmei; Yu, Zhaoliang; Dang, Junhua et al.

Part of Frontiers in Psychology, 2024

• DOI for Differentiating the relationships between traditional and new media use and sleep quality during the COVID-19 pandemic: roles of psychological distress and age
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Social support predicted subsequent subjective well-being during the COVID-19 pandemic: a prospective study

Mao, Yanhui; Chen, Junpeng; Liu, Xinqi; Dang, Junhua et al.

Part of BMC Public Health, 2024

• DOI for Social support predicted subsequent subjective well-being during the COVID-19 pandemic: a prospective study
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Long-term changes in adiposity markers during and after antidepressant therapy in a community cohort

Mwinyi, Jessica; Strippoli, Marie-Pierre F.; Kanders, Sofia H.; Schiöth, Helgi et al.

Part of Translational Psychiatry, 2024

• DOI for Long-term changes in adiposity markers during and after antidepressant therapy in a community cohort
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LEAP2 is associated with impulsivity and reward sensitivity depending on the nutritional status and decreases with protein intake in humans

Andreoli, María Florencia; Kruger, Ana Luz; Sokolov, Aleksandr V.; Rukh, Gull et al.

Part of Diabetes, obesity and metabolism, p. 4734-4743, 2024

• DOI for LEAP2 is associated with impulsivity and reward sensitivity depending on the nutritional status and decreases with protein intake in humans
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Hidden liver-joint axis: HBV infection causes rheumatoid arthritis via TRAFD1 with imbalance of HBV X protein and trans-ferulic acid

Zhao, Na; Zhang, Xiaoyu; Wang, Xilong; Liu, Zhipu et al.

Part of Virulence, 2024

• DOI for Hidden liver-joint axis: HBV infection causes rheumatoid arthritis via TRAFD1 with imbalance of HBV X protein and trans-ferulic acid
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The Concentration of Liver-Expressed Antimicrobial Peptide 2 in Human Milk and Infant Plasma Is Positively Associated with Adiposity and Body Weight in the First Year of Life

Kruger, Ana Luz; Malpeli, Agustina; Sala, Marisa; Casado, Carla et al.

Part of Journal of Nutrition, p. 3388-3399, 2024

• DOI for The Concentration of Liver-Expressed Antimicrobial Peptide 2 in Human Milk and Infant Plasma Is Positively Associated with Adiposity and Body Weight in the First Year of Life

Oxytocin pathway gene variation and corticostriatal resting-state functional connectivity

Xiao, Shanshan; Fischer, Håkan; Ebner, Natalie C.; Rukh, Gull et al.

Part of COMPREHENSIVE PSYCHONEUROENDOCRINOLOGY, 2024

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Genetic variants of LEAP2 are associated with anthropometric traits and circulating insulin-like growth factor-1 concentration: A UK Biobank study

Andreoli, María Florencia; Gentreau, Mélissa; Rukh, Gull; Perelló, Mario et al.

Part of Diabetes, obesity and metabolism, p. 3565-3575, 2024

• DOI for Genetic variants of LEAP2 are associated with anthropometric traits and circulating insulin-like growth factor-1 concentration: A UK Biobank study
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Genomic Validation in the UK Biobank Cohort Suggests a Role of C8B and MFG-E8 in the Pathogenesis of Trigeminal Neuralgia

Lafta, Muataz S.; Rukh, Gull; Abu Hamdeh, Sami; Molero, Yasmina et al.

Part of Journal of Molecular Neuroscience, 2024

• DOI for Genomic Validation in the UK Biobank Cohort Suggests a Role of C8B and MFG-E8 in the Pathogenesis of Trigeminal Neuralgia
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A deep learning model for brain age prediction using minimally preprocessed T1w images as input

Dartora, Caroline; Marseglia, Anna; Martensson, Gustav; Rukh, Gull et al.

Part of Frontiers in Aging Neuroscience, 2024

• DOI for A deep learning model for brain age prediction using minimally preprocessed T1w images as input
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Off-target effects of statins: molecular mechanisms, side effects and the emerging role of kinases

Lagunas-Rangel, Francisco Alejandro; Liepinsh, Edgars; Fredriksson, Robert; Alsehli, Ahmed M. et al.

Part of British Journal of Pharmacology, p. 3799-3818, 2024

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Hydroxymethylglutaryl-CoA reductase activity is essential for mitochondrial β-oxidation of fatty acids to prevent lethal accumulation of long-chain acylcarnitines in the mouse liver

Liepinsh, Edgars; Zvejniece, Liga; Clemensson, Laura; Ozola, Melita et al.

Part of British Journal of Pharmacology, p. 2750-2773, 2024

• DOI for Hydroxymethylglutaryl-CoA reductase activity is essential for mitochondrial β-oxidation of fatty acids to prevent lethal accumulation of long-chain acylcarnitines in the mouse liver
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Depression proteomic profiling in adolescents with transcriptome analyses in independent cohorts

Sokolov, Aleksandr V.; Lafta, Muataz; Nordberg, Didi; Jonsson, Jörgen et al.

Part of Frontiers in Psychiatry, 2024

• DOI for Depression proteomic profiling in adolescents with transcriptome analyses in independent cohorts
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Exploring biomarkers in trigeminal neuralgia patients operated with microvascular decompression: A comparison with multiple sclerosis patients and non-neurological controls

Lafta, Muataz S; Sokolov, Aleksandr V.; Landtblom, Anne-Marie; Ericson, Hans et al.

Part of European Journal of Pain, p. 929-942, 2024

• DOI for Exploring biomarkers in trigeminal neuralgia patients operated with microvascular decompression: A comparison with multiple sclerosis patients and non-neurological controls
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Selective Colocalization of GHSR and GLP-1R in a Subset of Hypothalamic Neurons and Their Functional Interaction

Aguggia, Julieta; Fernandez, Gimena; Cassano, Daniela; Mustafá, Emilio R. et al.

Part of Endocrinology, 2024

• DOI for Selective Colocalization of GHSR and GLP-1R in a Subset of Hypothalamic Neurons and Their Functional Interaction

Increased ROS levels, antioxidant defense disturbances and bioenergetic disruption induced by thiosulfate administration in the brain of neonatal rats

Manzke Glänzel, Nícolas; Teixeira da Rosa-Junior, Nevton; Signori, Marian F.; de Andrade Silveira, Josyane et al.

Part of Metabolic brain disease, 2024

• DOI for Increased ROS levels, antioxidant defense disturbances and bioenergetic disruption induced by thiosulfate administration in the brain of neonatal rats

Statin use is associated with higher white matter hyperintensity volumes and lower grey matter volumes

Gentreau, Mélissa; Miguet, Maud; Affatato, Oreste; Rukh, Gull et al.

Part of Brain Communications, 2024

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Advances in development of biomarkers for brain damage and ischemia

Karimova, Diana; Rostami, Elham; Chubarev, Vladimir N.; Tarasov, Vadim V. et al.

Part of Molecular Biology Reports, 2024

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Decoding depression: a comprehensive multi-cohort exploration of blood DNA methylation using machine learning and deep learning approaches

Sokolov, Aleksandr V.; Schiöth, Helgi

Part of Translational Psychiatry, 2024

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The exposure to UV filters: Prevalence, effects, possible molecular mechanisms of action and interactions within mixtures

Rafeletou, Alexandra; Niemi, Jenni; Lagunas-Rangel, Francisco Alejandro; Liu, Wen et al.

Part of Science of the Total Environment, 2024

• DOI for The exposure to UV filters: Prevalence, effects, possible molecular mechanisms of action and interactions within mixtures

Recent developments of topoisomerase inhibitors: Clinical trials, emerging indications, novel molecules and global sales

Bondarev, Andrey D.; Jonsson, Jörgen; Chubarev, Vladimir N.; V. Tarasov, Vadim et al.

Part of Pharmacological Research, 2024

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Blockade of the lncRNA-PART1-PHB2 axis confers resistance to PARP inhibitor and promotes cellular senescence in ovarian cancer

Wu, Huan; Sun, Chenggong; Cao, Wenyu; Teng, Qiuli et al.

Part of Cancer Letters, 2024

• DOI for Blockade of the lncRNA-PART1-PHB2 axis confers resistance to PARP inhibitor and promotes cellular senescence in ovarian cancer
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Association of polygenic scores for autism with volumetric MRI phenotypes in cerebellum and brainstem in adults

Mohammad, Salahuddin; Gentreau, Mélissa; Dubol, Manon; Rukh, Gull et al.

Part of Molecular Autism, 2024

• DOI for Association of polygenic scores for autism with volumetric MRI phenotypes in cerebellum and brainstem in adults
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Identifying proteomic risk factors for overall, aggressive, and early onset prostate cancer using Mendelian Randomisation and tumour spatial transcriptomics

Desai, Trishna A.; Hedman, Asa K.; Dimitriou, Marios; Koprulu, Mine et al.

Part of EBioMedicine, 2024

• DOI for Identifying proteomic risk factors for overall, aggressive, and early onset prostate cancer using Mendelian Randomisation and tumour spatial transcriptomics
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Identifying therapeutic targets for cancer among 2074 circulating proteins and risk of nine cancers

Smith-Byrne, Karl; Hedman, Åsa; Dimitriou, Marios; Desai, Trishna et al.

Part of Nature Communications, 2024

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Response to the Comment on "The Effects of Statins on Cognitive Performance Are Mediated by Low-Density Lipoprotein, C-Reactive Protein, and Blood Glucose Concentrations"

Gentreau, Melissa; Rukh, Gull; Miguet, Maud; Clemensson, Laura et al.

Part of The journals of gerontology. Series A, Biological sciences and medical sciences, 2024

• DOI for Response to the Comment on "The Effects of Statins on Cognitive Performance Are Mediated by Low-Density Lipoprotein, C-Reactive Protein, and Blood Glucose Concentrations"

STING inhibitors sensitize platinum chemotherapy in ovarian cancer by inhibiting the CGAS-STING pathway in cancer-associated fibroblasts (CAFs)

Liu, Jiale; Liu, Chenmian; Ma, Yana; Pan, Xiyu et al.

Part of Cancer Letters, 2024

• DOI for STING inhibitors sensitize platinum chemotherapy in ovarian cancer by inhibiting the CGAS-STING pathway in cancer-associated fibroblasts (CAFs)
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Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes

Al-Sabri, Mohamed H.; Ammar, Nourhane; Korzh, Stanislava; Alsehli, Ahmed M. et al.

Part of Scientific Reports, 2024

• DOI for Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes
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Synthesis of a Rivastigmine and Insulin Combinational Mucoadhesive Nanoparticle for Intranasal Delivery

Jamshidnejad-Tosaramandani, Tahereh; Kashanian, Soheila; Karimi, Isaac; Schiöth, Helgi

Part of Polymers, 2024

• DOI for Synthesis of a Rivastigmine and Insulin Combinational Mucoadhesive Nanoparticle for Intranasal Delivery
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Role of the hypothalamus in ghrelin effects on reproduction: sperm function and sexual behavior in male mice

Poretti, María Belén; Bianconi, Santiago; Luque, Eugenia; Martini, Ana Carolina et al.

Part of Reproduction, p. 123-134, 2023

• DOI for Role of the hypothalamus in ghrelin effects on reproduction: sperm function and sexual behavior in male mice

PLBD: protein-ligand binding database of thermodynamic and kinetic intrinsic parameters

Linge, Darius; Gedgaudas, Marius; Merkys, Andrius; Petrauskas, Vytautas et al.

Part of Database, 2023

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Perceived stress is related to lower blood pressure in a Swedish cohort

Miguet, Maud; Olivo, Gaia; Ciuculete, Diana-Maria; Elmståhl, Sölve et al.

Part of Scandinavian Journal of Public Health, p. 611-618, 2023

• DOI for Perceived stress is related to lower blood pressure in a Swedish cohort
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Job satisfaction and job tenure of people with mental health disorders: a UK Biobank cohort study

Mohammad, Salahuddin; Miguet, Maud; Rukh, Gull; Schiöth, Helgi B. et al.

Part of Scandinavian Journal of Public Health, p. 1248-1257, 2023

• DOI for Job satisfaction and job tenure of people with mental health disorders: a UK Biobank cohort study
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Worsened Anxiety and Loneliness Influenced Gaming and Gambling during the COVID-19 Pandemic

Mohamed, Mohamed S.; Rukh, Gull; Schiöth, Helgi B.; Vadlin, Sofia et al.

Part of Journal of Clinical Medicine, 2023

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Ghrelin's orexigenic action in the lateral hypothalamic area involves indirect recruitment of orexin neurons and arcuate nucleus activation

Barrile, Franco; Cassano, Daniela; Fernandez, Gimena; De Francesco, Pablo N. et al.

Part of Psychoneuroendocrinology, 2023

• DOI for Ghrelin's orexigenic action in the lateral hypothalamic area involves indirect recruitment of orexin neurons and arcuate nucleus activation

Methylation in MAD1L1 is associated with the severity of suicide attempt and phenotypes of depression

Sokolov, Aleksandr V.; Manu, Diana-Maria; Nordberg, Didi O. T.; Boström, Adrian D. E. et al.

Part of Clinical Epigenetics, 2023

• DOI for Methylation in MAD1L1 is associated with the severity of suicide attempt and phenotypes of depression
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The international clinical trials registry platform (ICTRP): data integrity and the trends in clinical trials, diseases, and drugs

Namiot, Eugenia D.; Smirnovová, Diana; Sokolov, Aleksandr V.; Chubarev, Vladimir N. et al.

Part of Frontiers in Pharmacology, 2023

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Synthesis of an insulin-loaded mucoadhesive nanoparticle designed for intranasal administration: focus on new diffusion media

Jamshidnejad-Tosaramandani, Tahereh; Kashanian, Soheila; Karimi, Isaac; Schiöth, Helgi B.

Part of Frontiers in Pharmacology, 2023

• DOI for Synthesis of an insulin-loaded mucoadhesive nanoparticle designed for intranasal administration: focus on new diffusion media
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Assessing volumetric brain differences in migraine and depression patients: a UK Biobank study

Affatato, Oreste; Dahlén, Amelia; Rukh, Gull; Schiöth, Helgi B. et al.

Part of BMC Neurology, 2023

• DOI for Assessing volumetric brain differences in migraine and depression patients: a UK Biobank study
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The Effects of Statins on Cognitive Performance Are Mediated by Low-Density Lipoprotein, C-Reactive Protein, and Blood Glucose Concentrations

Gentreau, Mélissa; Rukh, Gull; Miguet, Maud; Clemensson, Laura et al.

Part of The journals of gerontology. Series A, Biological sciences and medical sciences, p. 1964-1972, 2023

• DOI for The Effects of Statins on Cognitive Performance Are Mediated by Low-Density Lipoprotein, C-Reactive Protein, and Blood Glucose Concentrations
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Well-being spectrum traits are associated with polygenic scores for autism

Mohammad, Salahuddin; de Ruijter, Markus J. T.; Rukh, Gull; Rask-Andersen, Mathias et al.

Part of Autism Research, p. 1891-1902, 2023

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Volumetric Differences in Cerebellum and Brainstem in Patients with Migraine: A UK Biobank Study

Affatato, Oreste; Rukh, Gull; Schiöth, Helgi B.; Mwinyi, Jessica

Part of Biomedicines, 2023

• DOI for Volumetric Differences in Cerebellum and Brainstem in Patients with Migraine: A UK Biobank Study
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Migraine, inflammatory bowel disease and celiac disease: A Mendelian randomization study

Welander, Nike Zoe; Rukh, Gull; Rask-Andersen, Mathias; Harder, Aster V E et al.

Part of Headache, p. 642-651, 2023

• DOI for Migraine, inflammatory bowel disease and celiac disease: A Mendelian randomization study
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Artificial Neural Network (ANN)-Based Pattern Recognition Approach Illustrates a Biphasic Behavioral Effect of Ethanol in Zebrafish: A High-Throughput Method for Animal Locomotor Analysis

Myrov, Vladislav O; Polovian, Aleksandr I.; Kolchanova, Sofiia; Galumov, Georgii K et al.

Part of Biomedicines, 2023

• DOI for Artificial Neural Network (ANN)-Based Pattern Recognition Approach Illustrates a Biphasic Behavioral Effect of Ethanol in Zebrafish: A High-Throughput Method for Animal Locomotor Analysis
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Efficacy of combination therapy with GABA, a DPP-4i and a PPI as an adjunct to insulin therapy in patients with type 1 diabetes

Rabinovitch, Alexander; Koshelev, Daniil; Lagunas-Rangel, Francisco Alejandro; Kosheleva, Liudmila et al.

Part of Frontiers in Endocrinology, 2023

• DOI for Efficacy of combination therapy with GABA, a DPP-4i and a PPI as an adjunct to insulin therapy in patients with type 1 diabetes
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Evidence for Prepulse Inhibition of Visually Evoked Motor Response in Drosophila melanogaster

Schiöth, Helgi B.; Donzelli, Laura; Arvidsson, Nicklas; Williams, Michael J. et al.

Part of Biology, 2023

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Epigenetic changes in the CYP2D6 gene are related to severity of suicide attempt: A cross-sectional study of suicide attempters

Bostrom, Adrian E. Desai; Jamshidi, Esmail; Manu, Diana-Maria; Kular, Lara et al.

Part of Journal of Psychiatric Research, p. 217-224, 2023

• DOI for Epigenetic changes in the CYP2D6 gene are related to severity of suicide attempt: A cross-sectional study of suicide attempters
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Drosophila as a Rapid Screening Model to Evaluate the Hypoglycemic Effects of Dipeptidyl Peptidase 4 (DPP4) Inhibitors: High Evolutionary Conservation of DPP4

Lagunas-Rangel, Francisco Alejandro; Liao, Sifang; Williams, Michael J.; Trukhan, Vladimir et al.

Part of Biomedicines, 2023

• DOI for Drosophila as a Rapid Screening Model to Evaluate the Hypoglycemic Effects of Dipeptidyl Peptidase 4 (DPP4) Inhibitors: High Evolutionary Conservation of DPP4
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Evaluation of circulating plasma proteins in breast cancer using Mendelian randomisation

Mälarstig, Anders; Grassmann, Felix; Dahl, Leo; Dimitriou, Marios et al.

Part of Nature Communications, 2023

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Higher fresh fruit intake relates to larger grey matter volumes in areas involved in dementia and depression: A UK Biobank study

Gaudio, Santino; Rukh, Gull; Di Ciommo, Vincenzo; Berkins, Samuel et al.

Part of NeuroImage, 2023

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Fusobacterium nucleatum- induced exosomal HOTTIP promotes gastric cancer progression through the microRNA-885-3p/EphB2 axis

Xin, Yiwei; Li, Xinyang; Zhang, Mengjiao; Shang, Ziqi et al.

Part of Cancer Science, p. 2360-2374, 2023

• DOI for Fusobacterium nucleatum- induced exosomal HOTTIP promotes gastric cancer progression through the microRNA-885-3p/EphB2 axis
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Knockout of Tmlhe in mice is not associated with autism spectrum disorder phenotypes or motor dysfunction despite low carnitine levels

Liepinsh, Edgars; Svalbe, Baiba; Stelfa, Gundega; Grinberga, Solveiga et al.

Part of Molecular Autism, 2023

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Interaction between environmental pollutants and cancer drug efficacy: Bisphenol A, Bisphenol A diglycidyl ether and Perfluorooctanoic acid reduce vincristine cytotoxicity in acute lymphoblastic leukemia cells

Lagunas-Rangel, Francisco Alejandro; Liu, Wen; Schiöth, Helgi B.

Part of Journal of Applied Toxicology, p. 458-469, 2023

• DOI for Interaction between environmental pollutants and cancer drug efficacy: Bisphenol A, Bisphenol A diglycidyl ether and Perfluorooctanoic acid reduce vincristine cytotoxicity in acute lymphoblastic leukemia cells
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Effect of worry, depression, and sensitivity to environmental stress owing to neurotic personality on risk of cardiovascular disease: A Mendelian randomization study

Rukh, Gull; de Ruijter, Markus; Schiöth, Helgi Birgir

Part of Journal of personality, p. 856-867, 2023

• DOI for Effect of worry, depression, and sensitivity to environmental stress owing to neurotic personality on risk of cardiovascular disease: A Mendelian randomization study
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Job satisfaction has differential associations with delay discounting and risk-taking

de Ruijter, Markus J. T.; Dahlén, Amelia; Rukh, Gull; Schiöth, Helgi B.

Part of Scientific Reports, 2023

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Identification and validation of volatile organic compounds in bile for differential diagnosis of perihilar cholangiocarcinoma

Gui, Xinru; Zhang, Xin; Xin, Yiwei; Liu, Qi et al.

Part of Clinica Chimica Acta, 2023

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Effects of Transient Administration of the NMDA Receptor Antagonist MK-801 in Drosophila melanogaster Activity, Sleep, and Negative Geotaxis

Moulin, Thiago; Stojanovic, Tijana; Rajesh, Rasika P.; Pareek, Tirusha et al.

Part of Biomedicines, 2023

• DOI for Effects of Transient Administration of the NMDA Receptor Antagonist MK-801 in Drosophila melanogaster Activity, Sleep, and Negative Geotaxis
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How Sleep-Deprived People See and Evaluate Others' Faces: An Experimental Study

van Egmond, Lieve; Meth, Elisa; Bukhari, Shervin; Engström, Joachim et al.

Part of Nature and Science of Sleep, p. 867-876, 2022

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Generation of Endogenous Promoter-Driven Luciferase Reporter System Using CRISPR/Cas9 for Investigating Transcriptional Regulation of the Core Clock Gene BMAL1

Sun, Chengxi; Li, Su-Chen; Liu, Wen; Schiöth, Helgi B.

Part of Biomedicines, 2022

• DOI for Generation of Endogenous Promoter-Driven Luciferase Reporter System Using CRISPR/Cas9 for Investigating Transcriptional Regulation of the Core Clock Gene BMAL1
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The Statin Target HMG-Coenzyme a Reductase (Hmgcr) Regulates Sleep Homeostasis in Drosophila

Alsehli, Ahmed M.; Liao, Sifang; Al-Sabri, Mohamed H.; Vasionis, Lukas et al.

Part of Pharmaceuticals, 2022

• DOI for The Statin Target HMG-Coenzyme a Reductase (Hmgcr) Regulates Sleep Homeostasis in Drosophila
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Self-Reported Psychosomatic Complaints and Conduct Problems in Swedish Adolescents

Brooks, Samantha J.; Titova, Olga E; Ashworth, Emma L.; Bylund, Simon B. A. et al.

Part of Children, 2022

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HMDB 5.0: the Human Metabolome Database for 2022

Wishart, David S.; Guo, AnChi; Oler, Eponine; Wang, Fei et al.

Part of Nucleic Acids Research, 2022

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The influence of personality on the risk of myocardial infarction in UK Biobank cohort

Dahlén, Amelia; Miguet, Maud; Schiöth, Helgi B.; Rukh, Gull

Part of Scientific Reports, 2022

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The Statin Target Hmgcr Regulates Energy Metabolism and Food Intake through Central Mechanisms

Williams, Michael J.; Alsehli, Ahmed M.; Gartner, Sarah N.; Clemensson, Laura Emily et al.

Part of Cells, 2022

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Enhanced Toxicity of Bisphenols Together with UV Filters in Water: Identification of Synergy and Antagonism in Three-Component Mixtures

Kudlak, Blazej; Jatkowska, Natalia; Liu, Wen; Williams, Michael J. et al.

Part of Molecules, 2022

• DOI for Enhanced Toxicity of Bisphenols Together with UV Filters in Water: Identification of Synergy and Antagonism in Three-Component Mixtures
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Design, Synthesis and Biological Evaluation of Neogliptin, a Novel 2-Azabicyclo[2.2.1]heptane-Based Inhibitor of Dipeptidyl Peptidase-4 (DPP-4)

Maslov, Ivan O.; Zinevich, Tatiana; Kirichenko, Olga G.; Trukhan, Mikhail et al.

Part of Pharmaceuticals, 2022

• DOI for Design, Synthesis and Biological Evaluation of Neogliptin, a Novel 2-Azabicyclo[2.2.1]heptane-Based Inhibitor of Dipeptidyl Peptidase-4 (DPP-4)
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Can Exposure to Environmental Pollutants Be Associated with Less Effective Chemotherapy in Cancer Patients?

Lagunas-Rangel, Francisco Alejandro; Liu, Wen; Schiöth, Helgi B.

Part of International Journal of Environmental Research and Public Health, p. 2064-2064, 2022

• DOI for Can Exposure to Environmental Pollutants Be Associated with Less Effective Chemotherapy in Cancer Patients?
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Misdiagnosis of diabetic foot ulcer in patients with undiagnosed skin malignancies

Lyundup, Alexey V; Balyasin, Maxim V; Maksimova, Nadezhda V; Kovina, Marina V et al.

Part of International Wound Journal, p. 871-887, 2022

• DOI for Misdiagnosis of diabetic foot ulcer in patients with undiagnosed skin malignancies
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Statins Induce Locomotion and Muscular Phenotypes in Drosophila melanogaster That Are Reminiscent of Human Myopathy: Evidence for the Role of the Chloride Channel Inhibition in the Muscular Phenotypes

Al-Sabri, Mohamed H.; Behare, Neha; Alsehli, Ahmed M.; Berkins, Samuel et al.

Part of Cells, 2022

• DOI for Statins Induce Locomotion and Muscular Phenotypes in Drosophila melanogaster That Are Reminiscent of Human Myopathy: Evidence for the Role of the Chloride Channel Inhibition in the Muscular Phenotypes
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Triple drug therapy with GABA, sitagliptin, and omeprazole prevents type 1 diabetes onset and promotes its reversal in non-obese diabetic mice

Lagunas-Rangel, Francisco Alejandro; Koshelev, Daniil; Nedorubov, Andrej; Kosheleva, Liudmila et al.

Part of Frontiers in Endocrinology, 2022

• DOI for Triple drug therapy with GABA, sitagliptin, and omeprazole prevents type 1 diabetes onset and promotes its reversal in non-obese diabetic mice
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A simple high-throughput method for automated detection of Drosophila melanogaster light-dependent behaviours

Moulin, Thiago; Dey, Sovik; Dashi, Giovanna; Li, Lei et al.

Part of BMC Biology, 2022

• DOI for A simple high-throughput method for automated detection of Drosophila melanogaster light-dependent behaviours
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GHSR controls food deprivation-induced activation of CRF neurons of the hypothalamic paraventricular nucleus in a LEAP2-dependent manner

Fernandez, Gimena; Cabral, Agustina; De Francesco, Pablo N.; Uriarte, Maia et al.

Part of Cellular and Molecular Life Sciences (CMLS), 2022

• DOI for GHSR controls food deprivation-induced activation of CRF neurons of the hypothalamic paraventricular nucleus in a LEAP2-dependent manner

Identification of specific gene methylation patterns during motor neuron differentiation from spinal muscular atrophy patient-derived iPSC

Maretina, M. A.; Valetdinova, K. R.; Tsyganova, N. A.; Egorova, A. A. et al.

Part of Gene, 2022

• DOI for Identification of specific gene methylation patterns during motor neuron differentiation from spinal muscular atrophy patient-derived iPSC

Association of Diligence and Sociability with Stroke: A UK Biobank Study on Personality Proxies

de Ruijter, Markus J. T.; Dahlén, Amelia; Rukh, Gull; Schiöth, Helgi B.

Part of FRONTIERS IN BIOSCIENCE-LANDMARK, 2022

• DOI for Association of Diligence and Sociability with Stroke: A UK Biobank Study on Personality Proxies
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Dendritic spine density changes and homeostatic synaptic scaling: a meta-analysis of animal studies

Moulin, Thiago; Rayêe, Danielle; Schiöth, Helgi B.

Part of Neural Regeneration Research, p. 20-24, 2022

• DOI for Dendritic spine density changes and homeostatic synaptic scaling: a meta-analysis of animal studies
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Major sex differences in migraine prevalence among occupational categories: a cross-sectional study using UK Biobank

Affatato, Oreste; Miguet, Maud; Schiöth, Helgi B.; Mwinyi, Jessica

Part of Journal of Headache and Pain, 2021

• DOI for Major sex differences in migraine prevalence among occupational categories: a cross-sectional study using UK Biobank
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Migraine and gastrointestinal disorders in middle and old age: A UK Biobank study

Welander, Nike Zoe; Olivo, Gaia; Pisanu, Claudia; Rukh, Gull et al.

Part of Brain and Behavior, 2021

• DOI for Migraine and gastrointestinal disorders in middle and old age: A UK Biobank study
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Depression and Vegetarians: Association between Dietary Vitamin B6, B12 and Folate Intake and Global and Subcortical Brain Volumes

Berkins, Samuel; Schiöth, Helgi B.; Rukh, Gull

Part of Nutrients, 2021

• DOI for Depression and Vegetarians: Association between Dietary Vitamin B6, B12 and Folate Intake and Global and Subcortical Brain Volumes
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Migraine as a risk factor for mixed symptoms of peripartum depression and anxiety in late pregnancy: A prospective cohort study.

Welander, Nike Zoe; Mwinyi, Jessica; Asif, Sana; Schiöth, Helgi Birgir et al.

Part of Journal of Affective Disorders, p. 733-739, 2021

• DOI for Migraine as a risk factor for mixed symptoms of peripartum depression and anxiety in late pregnancy: A prospective cohort study.
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Time spent outdoors and risk of myocardial infarction and stroke in middle and old aged adults: Results from the UK Biobank prospective cohort

Miguet, Maud; Venetis, Sotirios; Rukh, Gull; Lind, Lars et al.

Part of Environmental Research, 2021

• DOI for Time spent outdoors and risk of myocardial infarction and stroke in middle and old aged adults: Results from the UK Biobank prospective cohort
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HPA axis dysregulation is associated with differential methylation of CpG-sites in related genes

Chatzittofis, Andreas; Bostrom, Adrian Desai E.; Ciuculete, Diana-Maria; Oberg, Katarina Gorts et al.

Part of Scientific Reports, 2021

• DOI for HPA axis dysregulation is associated with differential methylation of CpG-sites in related genes
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Characterization of five transmembrane proteins: With focus on the Tweety, Sidoreflexin, and YIP1 domain families

Attwood, Misty M.; Schiöth, Helgi B.

Part of Frontiers in Cell and Developmental Biology, 2021

• DOI for Characterization of five transmembrane proteins: With focus on the Tweety, Sidoreflexin, and YIP1 domain families
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Multidrug Resistance Like Protein 1 Activity in Malpighian Tubules Regulates Lipid Homeostasis in Drosophila

Liu, Wen; Cao, Hao; Kimari, Moses; Maronitis, Georgios et al.

Part of Membranes, 2021

• DOI for Multidrug Resistance Like Protein 1 Activity in Malpighian Tubules Regulates Lipid Homeostasis in Drosophila
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Differential associations of statin treatment and polymorphism in genes coding for HMGCR and PCSK9 to risk for insomnia

Alsehli, Ahmed M.; Clemensson, Laura Emily; Rukh, Gull; Ciuculete, Diana-Maria et al.

Part of Frontiers in Bioscience-Landmark, p. 1453-1463, 2021

• DOI for Differential associations of statin treatment and polymorphism in genes coding for HMGCR and PCSK9 to risk for insomnia
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LEAP2 Impairs the Capability of the Growth Hormone Secretagogue Receptor to Regulate the Dopamine 2 Receptor Signaling

Mustafá, Emilio R.; Cordisco González, Santiago; Damian, Marjorie; Cantel, Sonia et al.

Part of Frontiers in Pharmacology, 2021

• DOI for LEAP2 Impairs the Capability of the Growth Hormone Secretagogue Receptor to Regulate the Dopamine 2 Receptor Signaling
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Toll-like receptor 4 methylation grade is linked to depressive symptom severity

Rasmusson, Annica J.; Gallwitz, Maike; Soltanabadi, Bardia; Ciuculete, Diana-Maria et al.

Part of Translational Psychiatry, 2021

• DOI for Toll-like receptor 4 methylation grade is linked to depressive symptom severity
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BCNNM: A Framework for in silico Neural Tissue Development Modeling

Bozhko, Dmitrii V.; Galumov, Georgii K.; Polovian, Aleksandr I.; Kolchanova, Sofiia M. et al.

Part of Frontiers in Computational Neuroscience, 2021

• DOI for BCNNM: A Framework for in silico Neural Tissue Development Modeling
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Important gender differences in psychosomatic and school-related complaints in relation to adolescent weight status

Brooks, Samantha J.; Feldman, Inna; Schiöth, Helgi B.; Titova, Olga E

Part of Scientific Reports, 2021

• DOI for Important gender differences in psychosomatic and school-related complaints in relation to adolescent weight status
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Trends in kinase drug discovery: targets, indications and inhibitor design

Attwood, Misty M.; Fabbro, Doriano; Sokolov, Aleksandr V.; Knapp, Stefan et al.

Part of Nature reviews. Drug discovery, p. 839-861, 2021

• DOI for Trends in kinase drug discovery: targets, indications and inhibitor design

Association between migraine prevalence, treatment with proton-pump inhibitors and CYP2C19 phenotypes in UK Biobank

Pisanu, Claudia; Welander, Nike Zoe; Rukh, Gull; Schiöth, Helgi B. et al.

Part of Biomedicine and Pharmacotherapy, 2021

• DOI for Association between migraine prevalence, treatment with proton-pump inhibitors and CYP2C19 phenotypes in UK Biobank
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Differential DNA methylation of the genes for amyloid precursor protein, tau and neurofilaments in human traumatic brain injury

Abu Hamdeh, Sami; Ciuculete, Diana-Maria; Sarkisyan, Daniil; Bakalkin, Georgy et al.

Part of Journal of Neurotrauma, p. 1679-1688, 2021

• DOI for Differential DNA methylation of the genes for amyloid precursor protein, tau and neurofilaments in human traumatic brain injury

Recent developments of HDAC inhibitors: Emerging indications and novel molecules

Bondarev, Andrey D; Attwood, Misty M.; Jonsson, Jörgen; Chubarev, Vladimir N et al.

Part of British Journal of Clinical Pharmacology, p. 4577-4597, 2021

• DOI for Recent developments of HDAC inhibitors: Emerging indications and novel molecules
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Pharmacological treatment of migraine: Drug classes, mechanisms of action, clinical trials and new treatments

Zobdeh, Farzin; Ben Kraiem, Aziza; Attwood, Misty M.; Chubarev, Vladimir N et al.

Part of British Journal of Pharmacology, p. 4588-4607, 2021

• DOI for Pharmacological treatment of migraine: Drug classes, mechanisms of action, clinical trials and new treatments
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The Potential Effect of Insulin on AChE and Its Interactions with Rivastigmine In Vitro

Jamshidnejad-Tosaramandani, Tahereh; Kashanian, Soheila; Babaei, Mahsa; Al-Sabri, Mohamed et al.

Part of Pharmaceuticals, 2021

• DOI for The Potential Effect of Insulin on AChE and Its Interactions with Rivastigmine In Vitro
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Integrating Statistical and Machine-Learning Approach for Meta-Analysis of Bisphenol A-Exposure Datasets Reveals Effects on Mouse Gene Expression within Pathways of Apoptosis and Cell Survival

Lukashina, Nina; Williams, Michael J.; Kartysheva, Elena; Virko, Elizaveta et al.

Part of International Journal of Molecular Sciences, 2021

• DOI for Integrating Statistical and Machine-Learning Approach for Meta-Analysis of Bisphenol A-Exposure Datasets Reveals Effects on Mouse Gene Expression within Pathways of Apoptosis and Cell Survival
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The Drosophila melanogaster Levodopa-Induced Depression Model Exhibits Negative Geotaxis Deficits and Differential Gene Expression in Males and Females

Moulin, Thiago; Ferro, Federico; Hoyer, Angela; Cheung, Pierre et al.

Part of Frontiers in Neuroscience, 2021

• DOI for The Drosophila melanogaster Levodopa-Induced Depression Model Exhibits Negative Geotaxis Deficits and Differential Gene Expression in Males and Females
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Identification of synergistic and antagonistic actions of environmental pollutants: Bisphenols A, S and F in the presence of DEP, DBP, BADGE and BADGE center dot 2HCl in three component mixtures

Jatkowska, Natalia; Kudlak, Blazej; Lewandowska, Patrycja; Liu, Wen et al.

Part of Science of the Total Environment, 2021

• DOI for Identification of synergistic and antagonistic actions of environmental pollutants: Bisphenols A, S and F in the presence of DEP, DBP, BADGE and BADGE center dot 2HCl in three component mixtures

Dibutyl phthalate disrupts conserved circadian rhythm in Drosophila and human cells

Liu, Wen; Cao, Hao; Liao, Sifang; Kudlak, Blazej et al.

Part of Science of the Total Environment, 2021

• DOI for Dibutyl phthalate disrupts conserved circadian rhythm in Drosophila and human cells
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Neural activation of anxiety and depression in children and young people: A systematic meta-analysis of fMRI studies

Ashworth, Emma; Brooks, Samantha; Schiöth, Helgi B.

Part of Psychiatry Research, 2021

• DOI for Neural activation of anxiety and depression in children and young people: A systematic meta-analysis of fMRI studies
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A Multilab Replication of the Ego Depletion Effect

Dang, Junhua; Barker, Paul; Baumert, Anna; Bentvelzen, Margriet et al.

Part of Social Psychology and Personality Science, p. 14-24, 2021

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The Beauty of the Zero: Replications and Extensions of the Hidden-Zero Effect in Delay Discounting Tasks

Dang, Junhua; Liu, Xiaoping; Xiao, Shanshan; Mao, Lihua et al.

Part of Social Psychology and Personality Science, p. 544-549, 2021

• DOI for The Beauty of the Zero: Replications and Extensions of the Hidden-Zero Effect in Delay Discounting Tasks
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Ghrelin restores memory impairment following olfactory bulbectomy in mice by activating hippocampal NMDA1 and MAPK1 gene expression

Bianconi, Santiago; Poretti, María Belén; Rodriguez, Paula; Maestri, Giulia et al.

Part of Behavioural Brain Research, 2021

• DOI for Ghrelin restores memory impairment following olfactory bulbectomy in mice by activating hippocampal NMDA1 and MAPK1 gene expression

Differentiation of two human neuroblastoma cell lines alters SV2 expression patterns

Lekholm, Emilia; Ceder, Mikaela M.; Forsberg, Erica C.; Schiöth, Helgi B. et al.

Part of Cellular & Molecular Biology Letters (Druk), 2021

• DOI for Differentiation of two human neuroblastoma cell lines alters SV2 expression patterns
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Assessment of the granulation process effect on morpho-anatomical features and biologically active substances composition of senna leaves

Trifonova, Olga; Evdokimova, Olga; Prokofieva, Vera; Schiöth, Helgi B. et al.

Part of Farmacia, p. 44-50, 2021

• DOI for Assessment of the granulation process effect on morpho-anatomical features and biologically active substances composition of senna leaves

Classification of Trispanins: A Diverse Group of Proteins That Function in Membrane Synthesis and Transport Mechanisms

Attwood, Misty M.; Schiöth, Helgi B.

Part of Frontiers in Cell and Developmental Biology, 2020

• DOI for Classification of Trispanins: A Diverse Group of Proteins That Function in Membrane Synthesis and Transport Mechanisms
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Hypermethylation-associated downregulation of microRNA-4456 in hypersexual disorder with putative influence on oxytocin signalling: A DNA methylation analysis of miRNA genes

Boström, Adrian; Chatzittofis, Andreas; Ciuculete, Diana-Maria; Flanagan, John N. et al.

Part of Epigenetics, p. 145-160, 2020

• DOI for Hypermethylation-associated downregulation of microRNA-4456 in hypersexual disorder with putative influence on oxytocin signalling: A DNA methylation analysis of miRNA genes
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meQTL and ncRNA functional analyses of 102 GWAS-SNPs associated with depression implicate HACE1 and SHANK2 genes

Ciuculete, Diana-Maria; Voisin, Sarah; Kular, Lara; Jonsson, Jörgen et al.

Part of Clinical Epigenetics, 2020

• DOI for meQTL and ncRNA functional analyses of 102 GWAS-SNPs associated with depression implicate HACE1 and SHANK2 genes
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Draft genome sequences of Hirudo medicinalis and salivary transcriptome of three closely related medicinal leeches

Babenko, Vladislav V.; Podgorny, Oleg; Manuvera, Valentin A.; Kasianov, Artem S. et al.

Part of BMC Genomics, 2020

• DOI for Draft genome sequences of Hirudo medicinalis and salivary transcriptome of three closely related medicinal leeches
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Personality, lifestyle and job satisfaction: causal association between neuroticism and job satisfaction using Mendelian randomisation in the UK biobank cohort

Rukh, Gull; Dang, Junhua; Olivo, Gaia; Ciuculete, Diana-Maria et al.

Part of Translational Psychiatry, 2020

• DOI for Personality, lifestyle and job satisfaction: causal association between neuroticism and job satisfaction using Mendelian randomisation in the UK biobank cohort
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Excitability, synaptic balance, and addiction: The homeostatic dynamics of ionotropic glutamatergic receptors in VTA after cocaine exposure

Moulin, Thiago; Schiöth, Helgi B.

Part of Behavioral and Brain Functions, 2020

• DOI for Excitability, synaptic balance, and addiction: The homeostatic dynamics of ionotropic glutamatergic receptors in VTA after cocaine exposure
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Meal timing and subjective sleep disturbances in older men

van Egmond, Lieve T.; Moulin, Thiago C.; Schiöth, Helgi B.; Cederholm, Tommy et al.

Part of Experimental Gerontology, 2020

• DOI for Meal timing and subjective sleep disturbances in older men
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Association between sleep duration and executive function differs between diabetic and non-diabetic middle-aged and older adults.

Titova, Olga E; Lindberg, Eva; Tan, Xiao; Elmståhl, Sölve et al.

Part of Psychoneuroendocrinology, 2020

• DOI for Association between sleep duration and executive function differs between diabetic and non-diabetic middle-aged and older adults.
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Associations between chronotype, MTNR1B genotype and risk of type 2 diabetes in UK Biobank

Tan, Xiao; Ciuculete, Diana-Maria; Schiöth, Helgi B.; Benedict, Christian

Part of Journal of Internal Medicine, p. 189-196, 2020

• DOI for Associations between chronotype, MTNR1B genotype and risk of type 2 diabetes in UK Biobank

A pharmacogenetic risk score for the evaluation of major depression severity under treatment with antidepressants

Kanders, Sofia H.; Pisanu, Claudia; Bandstein, Marcus; Jonsson, Jörgen et al.

Part of Drug development research, p. 102-113, 2020

• DOI for A pharmacogenetic risk score for the evaluation of major depression severity under treatment with antidepressants
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The Cognitive Effects of Statins are Modified by Age

Alsehli, Ahmed M.; Olivo, Gaia; Clemensson, Laura Emily; Williams, Michael J. et al.

Part of Scientific Reports, 2020

• DOI for The Cognitive Effects of Statins are Modified by Age
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Longitudinal DNA methylation changes at MET may alter HGF/c-MET signalling in adolescents at risk for depression

Ciuculete, Diana Maria; Voisin, Sarah; Kular, Lara; Welihinda, Nipuni et al.

Part of Epigenetics, p. 646-663, 2020

• DOI for Longitudinal DNA methylation changes at MET may alter HGF/c-MET signalling in adolescents at risk for depression
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Is there prejudice from thin air?: Replicating the effect of emotion on automatic intergroup attitudes

Dang, Junhua; Ekim, Zeynep E.; Ohlsson, Sarah; Schiöth, Helgi B.

Part of BMC Psychology, 2020

• DOI for Is there prejudice from thin air?: Replicating the effect of emotion on automatic intergroup attitudes
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Important Difference between Occupational Hazard Exposure among Shift Workers and Other Workers; Comparing Workplace before and after 1980

Miguet, Maud; Rukh, Gull; Titova, Olga E; Schiöth, Helgi B.

Part of International Journal of Environmental Research and Public Health, 2020

• DOI for Important Difference between Occupational Hazard Exposure among Shift Workers and Other Workers; Comparing Workplace before and after 1980
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Normal Testosterone but Higher Luteinizing Hormone Plasma Levels in Men With Hypersexual Disorder

Chatzittofis, Andreas; Boström, Adrian; Görts Öberg, Katarina; Flanagan, John N. et al.

Part of Sexual Medicine, p. 243-250, 2020

• DOI for Normal Testosterone but Higher Luteinizing Hormone Plasma Levels in Men With Hypersexual Disorder
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Major depression subtypes are differentially associated with migraine subtype, prevalence and severity

Pisanu, Claudia; Lundin, Emma; Preisig, Martin; Gholam-Rezaee, Mehdi et al.

Part of Cephalalgia, p. 347-356, 2020

• DOI for Major depression subtypes are differentially associated with migraine subtype, prevalence and severity

Exposure to the environmental pollutant bisphenol A diglycidyl ether (BADGE) causes cell over-proliferation in Drosophila

Williams, Michael J.; Cao, Hao; Lindkvist, Therese; Mothes, Tobias J. et al.

Part of Environmental Science and Pollution Research, p. 25261-25270, 2020

• DOI for Exposure to the environmental pollutant bisphenol A diglycidyl ether (BADGE) causes cell over-proliferation in Drosophila
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CCAP regulates feeding behavior via the NPF pathway in Drosophila adults

Williams, Michael J.; Akram, Mehwish; Barkauskaite, Deimante; Patil, Sourabh et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 7401-7408, 2020

• DOI for CCAP regulates feeding behavior via the NPF pathway in Drosophila adults

Pharmacological NOS-1 Inhibition Within the Hippocampus Prevented Expression of Cocaine Sensitization: Correlation with Reduced Synaptic Transmission

de la Villarmois, Emilce; Gabach, Laura A.; Bianconi, Santiago; Poretti, Maria Belen et al.

Part of Molecular Neurobiology, p. 450-460, 2020

• DOI for Pharmacological NOS-1 Inhibition Within the Hippocampus Prevented Expression of Cocaine Sensitization: Correlation with Reduced Synaptic Transmission

Evidence that genes involved in hedgehog signaling are associated with both bipolar disorder and high BMI

Pisanu, Claudia; Williams, Michael J.; Ciuculete, Diana-Maria; Olivo, Gaia et al.

Part of Translational Psychiatry, 2019

• DOI for Evidence that genes involved in hedgehog signaling are associated with both bipolar disorder and high BMI
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Functional connectivity underlying hedonic response to food in female adolescents with atypical AN: The role of somatosensory and salience networks

Olivo, Gaia; Zhukovsky, Christina; Salonen-Ros, Helena; Larsson, Elna-Marie et al.

Part of Translational Psychiatry, 2019

• DOI for Functional connectivity underlying hedonic response to food in female adolescents with atypical AN: The role of somatosensory and salience networks
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A single night of sleep loss impairs objective but not subjective working memory performance in a sex-dependent manner

Rångtell, Frida H; Karamchedu, Swathy; Andersson, Peter; Liethof, Lisanne et al.

Part of Journal of Sleep Research, 2019

• DOI for A single night of sleep loss impairs objective but not subjective working memory performance in a sex-dependent manner
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Association Between Self-Reported Sleep Duration and Body Composition in Middle-Aged and Older Adults

Tan, Xiao; Titova, Olga E.; Lindberg, Eva; Elmståhl, Sölve et al.

Part of Journal of Clinical Sleep Medicine (JCSM), p. 431-435, 2019

• DOI for Association Between Self-Reported Sleep Duration and Body Composition in Middle-Aged and Older Adults

Growth hormone secretagogue receptor signalling affects high-fat intake independently of plasma levels of ghrelin and LEAP2, in a 4-day binge eating model

Paula Cornejo, Maria; Castrogiovanni, Daniel; Schiöth, Helgi B.; Reynaldo, Mirta et al.

Part of Journal of neuroendocrinology, 2019

• DOI for Growth hormone secretagogue receptor signalling affects high-fat intake independently of plasma levels of ghrelin and LEAP2, in a 4-day binge eating model

The polyamine transporter Slc18b1(VPAT) is important for both short and long time memory and for regulation of polyamine content in the brain.

Fredriksson, Robert; Sreedharan, Smitha; Nordenankar, Karin; Alsiö, Johan et al.

Part of PLOS Genetics, 2019

• DOI for The polyamine transporter Slc18b1(VPAT) is important for both short and long time memory and for regulation of polyamine content in the brain.
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Preserved white matter microstructure in adolescent patients with atypical anorexia nervosa

Olivo, Gaia; Swenne, Ingemar; Zhukovsky, Christina; Tuunainen, Anna-Kaisa et al.

Part of International Journal of Eating Disorders, p. 166-174, 2019

• DOI for Preserved white matter microstructure in adolescent patients with atypical anorexia nervosa
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Plasma levels of leptin and adiponectin and depressive symptoms in young adults

Syk, Mikaela; Ellström, Sofie; Mwinyi, Jessica; Schiöth, Helgi B. et al.

Part of Psychiatry Research, p. 1-7, 2019

• DOI for Plasma levels of leptin and adiponectin and depressive symptoms in young adults
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Memory consolidation impairment induced by Interleukin-1 beta is associated with changes in hippocampal structural plasticity

Herrera, Guadalupe; Calfa, Gaston; Schiöth, Helgi B.; Lasaga, Mercedes et al.

Part of Behavioural Brain Research, 2019

• DOI for Memory consolidation impairment induced by Interleukin-1 beta is associated with changes in hippocampal structural plasticity

Low neuroticism and cognitive performance are differently associated to overweight and obesity: A cross-sectional and longitudinal UK Biobank study.

Olivo, Gaia; Gour, Shaili; Schiöth, Helgi B.

Part of Psychoneuroendocrinology, p. 167-174, 2019

• DOI for Low neuroticism and cognitive performance are differently associated to overweight and obesity: A cross-sectional and longitudinal UK Biobank study.
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Testosterone, luteinizing hormone levels and methylation status in men with hypersexual disorders

Chatzittofis, A.; Boström, Adrian; Öberg, K.; Flanagan, J. et al.

Part of European Neuropsychopharmacology, 2019

• DOI for Testosterone, luteinizing hormone levels and methylation status in men with hypersexual disorders

Reproductive performance of male mice after hypothalamic ghrelin administration

Belen Poretti, Maria; Frautschi, Camila; Luque, Eugenia; Bianconi, Santiago et al.

Part of Reproduction, p. 121-132, 2018

• DOI for Reproductive performance of male mice after hypothalamic ghrelin administration

Acute sleep loss results in tissue-specific alterations in genome-wide DNA methylation state and metabolic fuel utilization in humans

Cedernaes, Jonathan; Schonke, Milena; Westholm, Jakub Orzechowski; Mi, Jia et al.

Part of Science Advances, 2018

• DOI for Acute sleep loss results in tissue-specific alterations in genome-wide DNA methylation state and metabolic fuel utilization in humans
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Associations Between the Prevalence of Metabolic Syndrome and Sleep Parameters Vary by Age

Titova, Olga E; Lindberg, Eva; Elmstahl, Solve; Lind, Lars et al.

Part of Frontiers in Endocrinology, 2018

• DOI for Associations Between the Prevalence of Metabolic Syndrome and Sleep Parameters Vary by Age
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Altered cerebellar-insular-parietal-cingular subnetwork in adolescents in the earliest stages of anorexia nervosa: a network-based statistic analysis

Gaudio, Santino; Olivo, Gaia; Zobel, Bruno Beomonte; Schiöth, Helgi B.

Part of Translational Psychiatry, 2018

• DOI for Altered cerebellar-insular-parietal-cingular subnetwork in adolescents in the earliest stages of anorexia nervosa: a network-based statistic analysis
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Reduced resting-state connectivity in areas involved in processing of face-related social cues in female adolescents with atypical anorexia nervosa

Olivo, Gaia; Swenne, Ingemar; Zhukovsky, Christina; Tuunainen, Anna-Kaisa et al.

Part of Translational Psychiatry, 2018

• DOI for Reduced resting-state connectivity in areas involved in processing of face-related social cues in female adolescents with atypical anorexia nervosa
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Disruption of Accumbens and Thalamic White Matter Connectivity Revealed by Diffusion Tensor Tractography in Young Men with Genetic Risk for Obesity

Olivo, Gaia; Latini, Francesco; Wiemerslage, Lyle; Larsson, Elna-Marie et al.

Part of Frontiers in Human Neuroscience, 2018

• DOI for Disruption of Accumbens and Thalamic White Matter Connectivity Revealed by Diffusion Tensor Tractography in Young Men with Genetic Risk for Obesity
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Intranasal insulin in Alzheimer's disease: food for thought

Chapman, Colin D; Schiöth, Helgi B.; Grillo, Claudia A; Benedict, Christian

Part of Neuropharmacology, p. 196-201, 2018

• DOI for Intranasal insulin in Alzheimer's disease: food for thought
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Self-reported sleep disturbances and prostate cancer morbidity and mortality in Swedish men: A longitudinal study over 40 years

Tan, Xiao; Cedernaes, Jonathan; Forsberg, Lars A.; Schiöth, Helgi B. et al.

Part of Journal of Sleep Research, 2018

• DOI for Self-reported sleep disturbances and prostate cancer morbidity and mortality in Swedish men: A longitudinal study over 40 years
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Changes in methylation within the STK32B promoter are associated with an increased risk for generalized anxiety disorder in adolescents

Ciuculete, Diana-Maria; Boström, Adrian E.; Tuunainen, Anna-Kaisa; Sohrabi, Farah et al.

Part of Journal of Psychiatric Research, p. 44-51, 2018

• DOI for Changes in methylation within the STK32B promoter are associated with an increased risk for generalized anxiety disorder in adolescents
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Atypical anorexia nervosa is not related to brain structural changes in newly diagnosed adolescent patients.

Olivo, Gaia; Solstrand Dahlberg, Linda; Wiemerslage, Lyle; Swenne, Ingemar et al.

Part of International Journal of Eating Disorders, p. 39-45, 2018

• DOI for Atypical anorexia nervosa is not related to brain structural changes in newly diagnosed adolescent patients.

Effects of dietary omega-3 PUFAs on growth and development: Somatic, neurobiological and reproductive functions in a murine model.

Bianconi, Santiago; Santillán, María E; Solís, María Del Rosario; Martini, Ana C et al.

Part of Journal of Nutritional Biochemistry, p. 82-90, 2018

• DOI for Effects of dietary omega-3 PUFAs on growth and development: Somatic, neurobiological and reproductive functions in a murine model.

Epigenetic Changes in the CRH Gene are Related to Severity of Suicide Attempt and a General Psychiatric Risk Score in Adolescents

Jokinen, Jussi; Boström, Adrian; Dadfar, Ali; Ciuculete, Diana-Maria et al.

Part of EBioMedicine, p. 123-133, 2018

• DOI for Epigenetic Changes in the CRH Gene are Related to Severity of Suicide Attempt and a General Psychiatric Risk Score in Adolescents
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Orphan Drugs and Their Impact on Pharmaceutical Development

Attwood, Misty M.; Rask-Andersen, Mathias; Schiöth, Helgi B.

Part of TIPS - Trends in Pharmacological Sciences, 2018

• DOI for Orphan Drugs and Their Impact on Pharmaceutical Development

Heterologous Expression, Biosynthetic Studies, and Ecological Function of the Selective Gq-Signaling Inhibitor FR900359

Crüsemann, Max; Reher, Raphael; Schamari, Isabella; Brachmann, Alexander O et al.

Part of Angewandte Chemie International Edition, p. 836-840, 2018

• DOI for Heterologous Expression, Biosynthetic Studies, and Ecological Function of the Selective Gq-Signaling Inhibitor FR900359

Diffusion tensor imaging and tractography of the white matter in normal aging: The rate-of-change differs between segments within tracts

Mårtensson, Johanna; Lätt, J.; Åhs, Fredrik; Fredriksson, Mats et al.

Part of Magnetic Resonance Imaging, p. 113-119, 2018

• DOI for Diffusion tensor imaging and tractography of the white matter in normal aging: The rate-of-change differs between segments within tracts

IL-1 beta reduces GluAl phosphorylation and its surface expression during memory reconsolidation and cc-melanocyte-stimulating hormone can modulate these effects

Machado, Ivana; Schiöth, Helgi B.; Lasaga, Mercedes; Scimonelli, Teresa

Part of Neuropharmacology, p. 314-323, 2018

• DOI for IL-1 beta reduces GluAl phosphorylation and its surface expression during memory reconsolidation and cc-melanocyte-stimulating hormone can modulate these effects

Plasma stearoyl-CoA desaturase activity indices and bile acid concentrations after a low-fat meal: association with a genetic variant in the FTO gene

Skuladottir, Gudrun Valgerdur; Oskarsdottir, Harpa; Pisanu, Claudia; Sjodin, Marcus et al.

Part of Diabetes, Metabolic Syndrome and Obesity, p. 611-618, 2018

• DOI for Plasma stearoyl-CoA desaturase activity indices and bile acid concentrations after a low-fat meal: association with a genetic variant in the FTO gene
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Significantly altered peripheral blood cell DNA methylation profile as a result of immediate effect of metformin use in healthy individuals

Elbere, Ilze; Silamikelis, Ivars; Ustinova, Monta; Kalnina, Ineta et al.

Part of Clinical Epigenetics, 2018

• DOI for Significantly altered peripheral blood cell DNA methylation profile as a result of immediate effect of metformin use in healthy individuals
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Severity of Suicide Attempt is Associated With Epigenetic and Transcriptional Changes in the CYP2D6 Gene

Jokinen, Jussi; Boström, Adrian; Åsberg, Marie; Schiöth, Helgi B.

Part of Biological Psychiatry, 2018

• DOI for Severity of Suicide Attempt is Associated With Epigenetic and Transcriptional Changes in the CYP2D6 Gene

A resting-state fMRI study of obese females between pre- and postprandial states before and after bariatric surgery.

Wiemerslage, Lyle; Zhou, Wei; Olivo, Gaia; Stark, Julia et al.

Part of European Journal of Neuroscience, p. 333-341, 2017

• DOI for A resting-state fMRI study of obese females between pre- and postprandial states before and after bariatric surgery.

Resting-state brain connectivity changes in obese women after Roux-en-Y gastric bypass surgery: A longitudinal study

Olivo, Gaia; Zhou, Wei; Sundbom, Magnus; Zhukovsky, Christina et al.

Part of Scientific Reports, 2017

• DOI for Resting-state brain connectivity changes in obese women after Roux-en-Y gastric bypass surgery: A longitudinal study
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A DNA methylation site within the KLF13 gene is associated with orexigenic processes based on neural responses and ghrelin levels

Wiemerslage, Lyle; Islam, R.; van der Kamp, C; Cao, Hao et al.

Part of International Journal of Obesity, p. 990-994, 2017

• DOI for A DNA methylation site within the KLF13 gene is associated with orexigenic processes based on neural responses and ghrelin levels

Inflammatory markers in late pregnancy in association with postpartum depression-A nested case-control study.

Bränn, Emma; Papadopoulos, Fotios; Fransson, Emma; White, Richard et al.

Part of Psychoneuroendocrinology, p. 146-159, 2017

• DOI for Inflammatory markers in late pregnancy in association with postpartum depression-A nested case-control study.
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A genetic risk score is differentially associated with migraine with and without aura

Pisanu, Claudia; Preisig, Martin; Castelao, Enrique; Glaus, Jennifer et al.

Part of Human Genetics, p. 999-1008, 2017

• DOI for A genetic risk score is differentially associated with migraine with and without aura
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Response to Leusink et al.

Ciuculete, Diana-Maria; Schiöth, Helgi B.; Mwinyi, Jessica

Part of Clinical Genetics, p. 566-566, 2017

• DOI for Response to Leusink et al.

Limbic-thalamo-cortical projections and reward-related circuitry integrity affects eating behavior: A longitudinal DTI study in adolescents with restrictive eating disorders

Olivo, Gaia; Wiemerslage, Lyle; Swenne, Ingemar; Zhukowsky, Christina et al.

Part of PLOS ONE, 2017

• DOI for Limbic-thalamo-cortical projections and reward-related circuitry integrity affects eating behavior: A longitudinal DTI study in adolescents with restrictive eating disorders
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A methylome-wide mQTL analysis reveals associations of methylation sites with GAD1 and HDAC3 SNPs and a general psychiatric risk score

Ciuculete, Diana-Maria; Boström, Adrian E.; Voisin, Sarah; Philipps, H. et al.

Part of Translational Psychiatry, 2017

• DOI for A methylome-wide mQTL analysis reveals associations of methylation sites with GAD1 and HDAC3 SNPs and a general psychiatric risk score
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Adolescents Newly Diagnosed with Eating Disorders have Structural Differences in Brain Regions linked with Eating Disorder Symptoms

Solstrand Dahlberg, Linda; Wiemerslage, Lyle; Swenne, Ingemar; Aronsson, Marianne et al.

Part of Nordic Journal of Psychiatry, p. 188-196, 2017

• DOI for Adolescents Newly Diagnosed with Eating Disorders have Structural Differences in Brain Regions linked with Eating Disorder Symptoms

Lower inflammatory markers in women with antenatal depression brings the M1/M2 balance into focus from a new direction

Edvinsson, Åsa; Bränn, Emma; Hellgren, Charlotte; Freyhult, Eva et al.

Part of Psychoneuroendocrinology, p. 15-25, 2017

• DOI for Lower inflammatory markers in women with antenatal depression brings the M1/M2 balance into focus from a new direction

A genetic risk score is significantly associated with statin therapy response in the elderly population

Ciuculete, Diana-Maria; Bandstein, Marcus; Benedict, Christian; Waeber, G. et al.

Part of Clinical Genetics, p. 379-385, 2017

• DOI for A genetic risk score is significantly associated with statin therapy response in the elderly population

Sex matters: Report experimenter gender

Chapman, Colin Daniel; Benedict, Christian; Schiöth, Helgi B.

Part of Science, p. 916-917, 2017

• DOI for Sex matters: Report experimenter gender

High leptin levels are associated with migraine with aura

Pisanu, Claudia; Preisig, Martin; Castelao, Enrique; Glaus, Jennifer et al.

Part of Cephalalgia, p. 435-441, 2017

• DOI for High leptin levels are associated with migraine with aura

Highly diversified expansions shaped the evolution of membrane bound proteins in metazoans

Attwood, Misty M.; Krishnan, Arunkumar; Sällman Almén, Markus; Schiöth, Helgi B.

Part of Scientific Reports, 2017

• DOI for Highly diversified expansions shaped the evolution of membrane bound proteins in metazoans
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A genetic variant in the catechol-O-methyl transferase (COMT) gene is related to age-dependent differences in the therapeutic effect of calcium-channel blockers

Xu, Jiayue; Boström, Adrian; Saeed, Mohamed; Dubey, Raghvendra K. et al.

Part of Medicine, 2017

• DOI for A genetic variant in the catechol-O-methyl transferase (COMT) gene is related to age-dependent differences in the therapeutic effect of calcium-channel blockers

NAFLD is associated with methylation shifts with relevance for the expression of genes involved in lipoprotein particle composition

Mwinyi, Jessica; Boström, Adrian; Pisanu, Claudia; Murphy, Susan K. et al.

Part of Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, p. 314-323, 2017

• DOI for NAFLD is associated with methylation shifts with relevance for the expression of genes involved in lipoprotein particle composition

Plasma 1-deoxysphingolipids are early predictors of incident type 2 diabetes mellitus

Mwinyi, Jessica; Boström, Adrian; Fehrer, I.; Othman, A. et al.

Part of PLOS ONE, 2017

• DOI for Plasma 1-deoxysphingolipids are early predictors of incident type 2 diabetes mellitus
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A MIR4646 associated methylation locus is hypomethylated in adolescent depression

Boström, Adrian; Ciuculete, Diana-Maria; Attwood, Misty M.; Krattinger, Regina et al.

Part of Journal of Affective Disorders, p. 117-128, 2017

• DOI for A MIR4646 associated methylation locus is hypomethylated in adolescent depression
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Trends in GPCR drug discovery: new agents, targets and indications

Hauser, Alexander S; Attwood, Misty M.; Rask-Andersen, Mathias; Schiöth, Helgi B. et al.

Part of Nature reviews. Drug discovery, p. 829-842, 2017

• DOI for Trends in GPCR drug discovery: new agents, targets and indications

Melanocortin 4 Receptor Constitutive Activity Inhibits L-Type Voltage-Gated Calcium Channels In Neurons

Agosti, F.; Cordisco Gonzalez, S.; Martinez Damonte, V.; Tolosa, M. J. et al.

Part of Neuroscience, p. 102-112, 2017

• DOI for Melanocortin 4 Receptor Constitutive Activity Inhibits L-Type Voltage-Gated Calcium Channels In Neurons

The impact of cognitive training in substance use disorder: the effect of working memory training on impulse control in methamphetamine users

Brooks, Samantha J.; Wiemerslage, L; Burch, K H; Maiorana, S A et al.

Part of Psychopharmacology, p. 1911-1921, 2017

• DOI for The impact of cognitive training in substance use disorder: the effect of working memory training on impulse control in methamphetamine users
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Anxiety Disorders are Associated with Low Socioeconomic Status in Women but Not in Men

Mwinyi, Jessica; Pisanu, Claudia; Castelao, Enrique; Stringhini, Silvia et al.

Part of Women's health issues, p. 302-307, 2017

• DOI for Anxiety Disorders are Associated with Low Socioeconomic Status in Women but Not in Men

Chemical probes to potently and selectively inhibit endocannabinoid cellular reuptake

Chicca, Andrea; Nicolussi, Simon; Bartholomäus, Ruben; Blunder, Martina et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, 2017

• DOI for Chemical probes to potently and selectively inhibit endocannabinoid cellular reuptake

Methylation of Hypothalamic-Pituitary-Adrenal Axis Related Genes in Men with Hypersexual Disorder

Jokinen, Jussi; Boström, Adrian; Chatzittofis, Andreas; Oberg, Katarina Gorts et al.

Part of Biological Psychiatry, 2017

• DOI for Methylation of Hypothalamic-Pituitary-Adrenal Axis Related Genes in Men with Hypersexual Disorder

Methylation of HPA axis related genes in men with hypersexual disorder

Jokinen, Jussi; Boström, Adrian E.; Chatzittofis, Andreas; Ciuculete, Diana-Maria et al.

Part of Psychoneuroendocrinology, p. 67-73, 2017

• DOI for Methylation of HPA axis related genes in men with hypersexual disorder

Methylation of the HPA axis related genes in men with hypersexual disorder

Jokinen, Jussi; Boström, Adrian; Chatzittofis, Andreas; Oberg, Katarina Gorts et al.

Part of Journal of Behavioral Addictions, p. 23-23, 2017

• DOI for Methylation of the HPA axis related genes in men with hypersexual disorder

Bis-(2-ethylhexyl) Phthalate Increases Insulin Expression and Lipid Levels in Drosophila melanogaster

Cao, Hao; Wiemerslage, Lyle; Marttila, Petra S. K.; Williams, Michael J. et al.

Part of Basic & Clinical Pharmacology & Toxicology, p. 309-316, 2016

• DOI for Bis-(2-ethylhexyl) Phthalate Increases Insulin Expression and Lipid Levels in Drosophila melanogaster

Higher resting-state activity in reward-related brain circuits in obese versus normal-weight females independent of food intake

Hogenkamp, Pleunie S.; Zhou, Wei; Dahlberg, Linda Solstrand; Stark, J. et al.

Part of International Journal of Obesity, p. 1687-1692, 2016

• DOI for Higher resting-state activity in reward-related brain circuits in obese versus normal-weight females independent of food intake
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A genetic variant in proximity to the gene LYPLAL1 is associated with lower hunger feelings and increased weight loss following Roux-en Y gastric bypass surgery

Bandstein, Marcus; Mwinyi, Jessica; Ernst, Barbara; Thurnheer, Martin et al.

Part of Scandinavian Journal of Gastroenterology, p. 1050-1055, 2016

• DOI for A genetic variant in proximity to the gene LYPLAL1 is associated with lower hunger feelings and increased weight loss following Roux-en Y gastric bypass surgery
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One-night sleep deprivation induces changes in the DNA methylation and serum activity indices of stearoyl-CoA desaturase in young healthy men

Skuladottir, Gudrun Valgerdur; Nilsson, Emil Karl; Mwinyi, Jessica; Schiöth, Helgi Birgir

Part of Lipids in Health and Disease, 2016

• DOI for One-night sleep deprivation induces changes in the DNA methylation and serum activity indices of stearoyl-CoA desaturase in young healthy men
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microRNA-192 suppresses the expression of the farnesoid X receptor

Krattinger, Regina; Boström, Adrian; Schiöth, Helgi B.; Thasler, Wolfgang E. et al.

Part of American Journal of Physiology - Gastrointestinal and Liver Physiology, 2016

• DOI for microRNA-192 suppresses the expression of the farnesoid X receptor

Longitudinal genome-wide methylation study of Roux-en-Y gastric bypass patients reveals novel CpG sites associated with essential hypertension

Boström, Adrian E.; Mwinyi, Jessica; Voisin, Sarah; Wu, Wenting et al.

Part of BMC Medical Genomics, 2016

• DOI for Longitudinal genome-wide methylation study of Roux-en-Y gastric bypass patients reveals novel CpG sites associated with essential hypertension
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Epigenomics of Total Acute Sleep Deprivation in Relation to Genome-Wide DNA Methylation Profiles and RNA Expression

Nilsson, Emil K.; Boström, Adrian E.; Mwinyi, Jessica; Schiöth, Helgi B.

Part of Omics, p. 334-342, 2016

• DOI for Epigenomics of Total Acute Sleep Deprivation in Relation to Genome-Wide DNA Methylation Profiles and RNA Expression

A genetic risk score is associated with weight loss following Roux-Y gastric bypass surgery

Bandstein, Marcus; Voisin, Sarah; Nilsson, Emil; Schultes, Bernd et al.

Part of Obesity Surgery, p. 2183-2189, 2016

• DOI for A genetic risk score is associated with weight loss following Roux-Y gastric bypass surgery
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mRNA GPR162 changes are associated with decreased food intake in rat, and its human genetic variants with impairments in glucose homeostasis in two Swedish cohorts

Caruso, Vanni; Sreedharan, Smitha; Carlini, Valeria P.; Jacobsson, Josefin A. et al.

Part of Gene, p. 139-145, 2016

• DOI for mRNA GPR162 changes are associated with decreased food intake in rat, and its human genetic variants with impairments in glucose homeostasis in two Swedish cohorts

Recurrent Sleep Fragmentation Induces Insulin and Neuroprotective Mechanisms in Middle-Aged Flies

Williams, Michael J.; Perland, Emelie; Eriksson, Mikaela M.; Carlsson, Josef et al.

Part of Frontiers in Aging Neuroscience, 2016

• DOI for Recurrent Sleep Fragmentation Induces Insulin and Neuroprotective Mechanisms in Middle-Aged Flies
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Psychological intervention with working memory training increases basal ganglia volume: A VBM study of inpatient treatment for methamphetamine use

Brooks, S. J.; Burch, K. H.; Maiorana, S. A.; Cocolas, E. et al.

Part of NeuroImage, p. 478-491, 2016

• DOI for Psychological intervention with working memory training increases basal ganglia volume: A VBM study of inpatient treatment for methamphetamine use
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A targeted analysis reveals relevant shifts in the methylation and transcription of genes responsible for bile acid homeostasis and drug metabolism in non-alcoholic fatty liver disease

Schiöth, Helgi B.; Boström, Adrian; Murphy, Susan K.; Erhart, Wiebke et al.

Part of BMC Genomics, 2016

• DOI for A targeted analysis reveals relevant shifts in the methylation and transcription of genes responsible for bile acid homeostasis and drug metabolism in non-alcoholic fatty liver disease
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Resting-State Bra in and the FTO Obesity Risk Allele: Default Mode, Sensorimotor, and Salience Network Connectivity Underlying Different Somatosensory Integration and Reward Processing between Genotypes

Olivo, Gaia; Wiemerslage, Lyle; Nilsson, Emil K.; Dahlberg, Linda Solstrand et al.

Part of Frontiers in Human Neuroscience, 2016

• DOI for Resting-State Bra in and the FTO Obesity Risk Allele: Default Mode, Sensorimotor, and Salience Network Connectivity Underlying Different Somatosensory Integration and Reward Processing between Genotypes
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Topology based identification and comprehensive classification of four-transmembrane helix containing proteins (4TMs) in the human genome

Attwood, Misty M.; Krishnan, Arunkumar; Pivotti, Valentina; Yazdi, Samira et al.

Part of BMC Genomics, 2016

• DOI for Topology based identification and comprehensive classification of four-transmembrane helix containing proteins (4TMs) in the human genome
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Postprandial alterations in whole-blood DNA methylation are mediated by changes in white blood cell composition

Rask-Andersen, Mathias; Bringeland, Nathalie; Nilsson, Emil K.; Bandstein, Marcus et al.

Part of American Journal of Clinical Nutrition, p. 518-525, 2016

• DOI for Postprandial alterations in whole-blood DNA methylation are mediated by changes in white blood cell composition

Two hours of evening reading on a self-luminous tablet vs. reading a physical book does not alter sleep after daytime bright light exposure

Rångtell, Frida H.; Ekstrand, Emelie; Rapp, Linnea; Lagermalm, Anna et al.

Part of Sleep Medicine, p. 111-118, 2016

• DOI for Two hours of evening reading on a self-luminous tablet vs. reading a physical book does not alter sleep after daytime bright light exposure
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Association between shift work history and performance on the trail making test in middle-aged and elderly humans: the EpiHealth study

Titova, Olga E; Lindberg, Eva; Elmståhl, Sölve; Lind, Lars et al.

Part of Neurobiology of Aging, p. 23-29, 2016

• DOI for Association between shift work history and performance on the trail making test in middle-aged and elderly humans: the EpiHealth study
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An obesity-associated risk allele within the FTO gene affects human brain activity for areas important for emotion, impulse control and reward in response to food images

Wiemerslage, Lyle; Nilsson, Emil K.; Dahlberg, Linda Solstrand; Ence-Eriksson, Fia et al.

Part of European Journal of Neuroscience, p. 1173-1180, 2016

• DOI for An obesity-associated risk allele within the FTO gene affects human brain activity for areas important for emotion, impulse control and reward in response to food images

Learning and sleep-dependent consolidation of spatial and procedural memories are unaltered in young men under a fixed short sleep schedule

Cedernaes, Jonathan; Sand, Filip; Liethof, Lisanne; Lampola, Lauri et al.

Part of Neurobiology of Learning and Memory, p. 87-94, 2016

• DOI for Learning and sleep-dependent consolidation of spatial and procedural memories are unaltered in young men under a fixed short sleep schedule
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A single night of partial sleep loss impairs fasting insulin sensitivity but does not affect cephalic phase insulin release in young men

Cedernaes, Jonathan; Lampola, Lauri; Axelsson, Emil K; Liethof, Lisanne et al.

Part of Journal of Sleep Research, p. 5-10, 2016

• DOI for A single night of partial sleep loss impairs fasting insulin sensitivity but does not affect cephalic phase insulin release in young men
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Oxytocin Acting in the Nucleus Accumbens Core Decreases Food Intake

Herisson, F. M.; Waas, J. R.; Fredriksson, Robert; Schiöth, Helgi B. et al.

Part of Journal of neuroendocrinology, 2016

• DOI for Oxytocin Acting in the Nucleus Accumbens Core Decreases Food Intake

The Drosophila ETV5 homologue Ets96B: Molecular link between obesity and bipolar disorder

Williams, Michael; Klockars, Anica; Eriksson, Anders; Voisin, Sarah et al.

Part of PLOS Genetics, 2016

• DOI for The Drosophila ETV5 homologue Ets96B: Molecular link between obesity and bipolar disorder
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A new, simple and robust radioligand binding method used to determine kinetic off-rate constants for unlabeled ligands. Application at alpha(2A)- and alpha(2C)-adrenoceptors

Uhlén, Staffan; Schiöth, Helgi B.; Jahnsen, Jan Anker

Part of European Journal of Pharmacology, p. 113-121, 2016

• DOI for A new, simple and robust radioligand binding method used to determine kinetic off-rate constants for unlabeled ligands. Application at alpha(2A)- and alpha(2C)-adrenoceptors
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Chenodeoxycholic acid significantly impacts the expression of miRNAs and genes involved in lipid, bile acid and drug metabolism in human hepatocytes

Krattinger, Regina; Boström, Adrian; Lee, Serene M. L.; Thasler, Wolfgang E. et al.

Part of Life Sciences, p. 47-56, 2016

• DOI for Chenodeoxycholic acid significantly impacts the expression of miRNAs and genes involved in lipid, bile acid and drug metabolism in human hepatocytes
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Reduced vasopressin receptors activation mediates the anti-depressant effects of fluoxetine and venlafaxine in bulbectomy model of depression

Poretti, María Belén; Sawant, Rahul S; Rask-Andersen, Mathias; de Cuneo, Marta Fiol et al.

Part of Psychopharmacology, p. 1077-1086, 2016

• DOI for Reduced vasopressin receptors activation mediates the anti-depressant effects of fluoxetine and venlafaxine in bulbectomy model of depression

Sleep restriction alters plasma endocannabinoids concentrations before but not after exercise in humans

Cedernaes, Jonathan; Fanelli, Flaminia; Fazzini, Alessia; Pagotto, Uberto et al.

Part of Psychoneuroendocrinology, p. 258-268, 2016

• DOI for Sleep restriction alters plasma endocannabinoids concentrations before but not after exercise in humans
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Dibutyl Phthalate Exposure Disrupts Evolutionarily Conserved Insulin and Glucagon-Like Signaling in Drosophila Males

Williams, Michael J.; Wiemerslage, Lyle; Gohel, Priya; Kheder, Sania et al.

Part of Endocrinology, p. 2309-2321, 2016

• DOI for Dibutyl Phthalate Exposure Disrupts Evolutionarily Conserved Insulin and Glucagon-Like Signaling in Drosophila Males

The Drosophila ortholog of TMEM18 regulates insulin and glucagon-like signaling

Wiemerslage, Lyle; Gohel, Priya A.; Maestri, Giulia; Hilmarsson, Torfi G. et al.

Part of Journal of Endocrinology, p. 233-243, 2016

• DOI for The Drosophila ortholog of TMEM18 regulates insulin and glucagon-like signaling

Association of the LINGO2-related SNP rs10968576 with body mass in a cohort of elderly Swedes

Rask-Andersen, Mathias; Almén, Markus Sällman; Lind, Lars; Schiöth, Helgi B.

Part of Molecular Genetics and Genomics, p. 1485-1491, 2015

• DOI for Association of the LINGO2-related SNP rs10968576 with body mass in a cohort of elderly Swedes

Determination of obesity associated gene variants related to TMEM18 through ultra-deep targeted re-sequencing in a case-control cohort for pediatric obesity.

Rask-Andersen, Mathias; Sällman Almén, Markus; Jacobsson, Josefin A; Ameur, Adam et al.

Part of Genetical Research, 2015

• DOI for Determination of obesity associated gene variants related to TMEM18 through ultra-deep targeted re-sequencing in a case-control cohort for pediatric obesity.

Dietary fat quality impacts genome-wide DNA methylation patterns in a cross-sectional study of Greek preadolescents

Voisin, Sarah; Almén, Markus S; Moschonis, George; Chrousos, George P et al.

Part of European Journal of Human Genetics, p. 654-662, 2015

• DOI for Dietary fat quality impacts genome-wide DNA methylation patterns in a cross-sectional study of Greek preadolescents

Defining the gene repertoire and spatiotemporal expression profiles of adhesion G protein-coupled receptors in zebrafish

Harty, Breanne L.; Krishnan, Arunkumar; Sanchez, Nicholas E.; Schiöth, Helgi B. et al.

Part of BMC Genomics, 2015

• DOI for Defining the gene repertoire and spatiotemporal expression profiles of adhesion G protein-coupled receptors in zebrafish
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Scrutinizing the FTO locus: compelling evidence for a complex, long-range regulatory context

Rask-Andersen, Mathias; Almén, Markus Sallman; Schiöth, Helgi B.

Part of Human Genetics, p. 1183-1193, 2015

• DOI for Scrutinizing the FTO locus: compelling evidence for a complex, long-range regulatory context

Kiwi genome provides insights into evolution of a nocturnal lifestyle

Le Duc, Diana; Renaud, Gabriel; Krishnan, Arunkumar; Almén, Markus Sällman et al.

Part of Genome Biology, 2015

• DOI for Kiwi genome provides insights into evolution of a nocturnal lifestyle
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Roux-En Y Gastric Bypass Surgery Induces Genome-Wide Promoter-Specific Changes in DNA Methylation in Whole Blood of Obese Patients

Nilsson, Emil; Ernst, Barbara; Voisin, Sarah; Sällman Almén, Markus et al.

Part of PLOS ONE, 2015

• DOI for Roux-En Y Gastric Bypass Surgery Induces Genome-Wide Promoter-Specific Changes in DNA Methylation in Whole Blood of Obese Patients
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Many obesity-associated SNPs strongly associate with DNA methylation changes at proximal promoters and enhancers

Voisin, Sarah; Almén, Markus Sällman; Zheleznyakova, Galina Y.; Lundberg, Lina et al.

Part of Genome Medicine, 2015

• DOI for Many obesity-associated SNPs strongly associate with DNA methylation changes at proximal promoters and enhancers
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Implication of coronin 7 in body weight regulation in humans, mice and flies

Eriksson, Anders; Williams, Michael J.; Voisin, Sarah; Hansson, Ida et al.

Part of BMC Neuroscience, 2015

• DOI for Implication of coronin 7 in body weight regulation in humans, mice and flies
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Acute Sleep Loss Induces Tissue-Specific Epigenetic and Transcriptional Alterations to Circadian Clock Genes in Men

Cedernaes, Jonathan; Osler, Megan E.; Voisin, Sarah; Broman, Jan-Erik et al.

Part of Journal of Clinical Endocrinology and Metabolism, 2015

• DOI for Acute Sleep Loss Induces Tissue-Specific Epigenetic and Transcriptional Alterations to Circadian Clock Genes in Men

The Role of FTO and Vitamin D for the Weight Loss Effect of Roux-en-Y Gastric Bypass Surgery in Obese Patients

Bandstein, Marcus; Schultes, Bernd; Ernst, Barbara; Thurnheer, Martin et al.

Part of Obesity Surgery, p. 2071-2077, 2015

• DOI for The Role of FTO and Vitamin D for the Weight Loss Effect of Roux-en-Y Gastric Bypass Surgery in Obese Patients
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Determinants of Shortened, Disrupted, and Mistimed Sleep and Associated Metabolic Health Consequences in Healthy Humans

Cedernaes, Jonathan; Schiöth, Helgi B.; Benedict, Christian

Part of Diabetes, p. 1073-1080, 2015

• DOI for Determinants of Shortened, Disrupted, and Mistimed Sleep and Associated Metabolic Health Consequences in Healthy Humans

Short Sleep Makes Declarative Memories Vulnerable to Stress in Humans

Cedernaes, Jonathan; Rångtell, Frida H.; Axelsson, Emil K.; Yeganeh, Adine et al.

Part of Sleep, p. 1861-1868, 2015

• DOI for Short Sleep Makes Declarative Memories Vulnerable to Stress in Humans

Television Watching and Effects on Food Intake: Distress vs Eustress

Benedict, Christian; Schiöth, Helgi B.; Cedernaes, Jonathan

Part of JAMA Internal Medicine, p. 468-468, 2015

Self-reported sleep disturbance is associated with Alzheimer's disease risk in men

Benedict, Christian; Byberg, Liisa; Cedernaes, Jonathan; Hogenkamp, Pleunie S et al.

Part of Alzheimer's & Dementia, p. 1090-1097, 2015

• DOI for Self-reported sleep disturbance is associated with Alzheimer's disease risk in men
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Associations of self-reported sleep disturbance and duration with academic failure in community-dwelling Swedish adolescents: Sleep and academic performance at school

Titova, Olga E; Hogenkamp, Pleunie S; Jacobsson, Josefin A; Feldman, Inna et al.

Part of Sleep Medicine, p. 87-93, 2015

• DOI for Associations of self-reported sleep disturbance and duration with academic failure in community-dwelling Swedish adolescents: Sleep and academic performance at school
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Patients Lacking Sustainable Long-Term Weight Loss after Gastric Bypass Surgery Show Signs of Decreased Inhibitory Control of Prepotent Responses

Hogenkamp, Pleunie S.; Sundbom, Magnus; Nilsson, Victor C.; Benedict, Christian et al.

Part of PLOS ONE, 2015

• DOI for Patients Lacking Sustainable Long-Term Weight Loss after Gastric Bypass Surgery Show Signs of Decreased Inhibitory Control of Prepotent Responses
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Are you sure?: Confidence about the satiating capacity of a food affects subsequent food intake

Schiöth, Helgi; Ferriday, Danielle; Davies, Sarah; Benedict, Christian et al.

Part of Nutrients, p. 5088-5097, 2015

• DOI for Are you sure?: Confidence about the satiating capacity of a food affects subsequent food intake
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The Orphan G Protein-Coupled Receptor Gene GPR178 Is Evolutionary Conserved and Altered in Response to Acute Changes in Food Intake

Caruso, Vanni; Le Greves, Madeleine; Fard, Shahrzad Shirazi; Haitina, Tatjana et al.

Part of PLOS ONE, 2015

• DOI for The Orphan G Protein-Coupled Receptor Gene GPR178 Is Evolutionary Conserved and Altered in Response to Acute Changes in Food Intake
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Methylation Levels of SLC23A2 and NCOR2 Genes Correlate with Spinal Muscular Atrophy Severity

Zheleznyakova, Galina Yu; Nilsson, Emil K.; Kiselev, Anton V.; Maretina, Marianna A. et al.

Part of PLOS ONE, 2015

• DOI for Methylation Levels of SLC23A2 and NCOR2 Genes Correlate with Spinal Muscular Atrophy Severity
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The obesity-linked Nudt3 Drosophila homolog Aps is associated with insulin signalling

Williams, Michael; Eriksson, Anders; Shaik, Muksheed; Voisin, Sarah et al.

Part of Molecular Endocrinology, p. 1303-1319, 2015

• DOI for The obesity-linked Nudt3 Drosophila homolog Aps is associated with insulin signalling

Ghrelin effects expression of several genes associated with depression-like behavior

Poretti, María Belén; Rask-Andersen, Mathias; Kumar, Praveen; Rubiales de Barioglio, Susana et al.

Part of Progress in Neuro-psychopharmacology and Biological Psychiatry, p. 227-234, 2015

• DOI for Ghrelin effects expression of several genes associated with depression-like behavior

Ghrelin increases memory consolidation through hippocampal mechanisms dependent on glutamate release and NR2B-subunits of the NMDA receptor

Ghersi, Marisa S; Gabach, L A; Buteler, F; Vilcaes, A A et al.

Part of Psychopharmacology, p. 1843-1857, 2015

• DOI for Ghrelin increases memory consolidation through hippocampal mechanisms dependent on glutamate release and NR2B-subunits of the NMDA receptor

Interleukin-1 beta-induced memory reconsolidation impairment is mediated by a reduction in glutamate release and zif268 expression and alpha-melanocyte-stimulating hormone prevented these effects

Machado, Ivana; Gonzalez, Patricia V.; Vilcaes, Alejandro; Carniglia, Lila et al.

Part of Brain, behavior, and immunity, p. 137-146, 2015

• DOI for Interleukin-1 beta-induced memory reconsolidation impairment is mediated by a reduction in glutamate release and zif268 expression and alpha-melanocyte-stimulating hormone prevented these effects

MicroRNA-192 regulates the expression of the farnesoid X receptor

Krattinger, Regina; Mwinyi, Jessica; Kullak-Ublick, Gerd A.; Schiöth, Helgi B. et al.

Part of Hepatology, 2015

Evolutionary hierarchy of vertebrate-like heterotrimeric G protein families

Krishnan, Arunkumar; Mustafa, Arshi; Almén, Markus Sällman; Fredriksson, Robert et al.

Part of Molecular Phylogenetics and Evolution, p. 27-40, 2015

• DOI for Evolutionary hierarchy of vertebrate-like heterotrimeric G protein families

Gabaergic control of anxiety-like behavior, but not food intake, induced by ghrelin in the intermediate medial mesopallium of the neonatal chick

Gaston, M. S.; Schiöth, Helgi B.; De Barioglio, S. R.; Salvatierra, N. A.

Part of Hormones and Behavior, p. 66-72, 2015

• DOI for Gabaergic control of anxiety-like behavior, but not food intake, induced by ghrelin in the intermediate medial mesopallium of the neonatal chick

The fat mass and obesity-associated gene (FTO) is linked to higher plasma levels of the hunger hormone ghrelin and lower serum levels of the satiety hormone leptin in older adults

Benedict, Christian; Axelsson, Tomas; Söderberg, Stefan; Larsson, Anders et al.

Part of Diabetes, p. 3955-3959, 2014

• DOI for The fat mass and obesity-associated gene (FTO) is linked to higher plasma levels of the hunger hormone ghrelin and lower serum levels of the satiety hormone leptin in older adults

Increased Impulsivity in Response to Food Cues after Sleep Loss in Healthy Young Men

Cedernaes, Jonathan; Brandell, Jon; Ros, Olof; Broman, Jan-Erik et al.

Part of Obesity, p. 1786-1791, 2014

• DOI for Increased Impulsivity in Response to Food Cues after Sleep Loss in Healthy Young Men
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Long-term oral melatonin administration reduces ethanol-induced increases in duodenal mucosal permeability and motility in rats

Sommansson, Anna; Yamskova, Olga; Schiöth, Helgi B.; Nylander, Olof et al.

Part of Acta Physiologica, p. 152-165, 2014

• DOI for Long-term oral melatonin administration reduces ethanol-induced increases in duodenal mucosal permeability and motility in rats

Genome-wide analysis reveals DNA methylation markers that vary with both age and obesity

Almén, Markus Sällman; Nilsson, Emil K.; Jacobsson, Josefin A.; Kalnina, Ineta et al.

Part of Gene, p. 61-67, 2014

• DOI for Genome-wide analysis reveals DNA methylation markers that vary with both age and obesity
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The GPCR repertoire in the demosponge Amphimedon queenslandica: insights into the GPCR system at the early divergence of animals

Krishnan, Arunkumar; Dnyansagar, Rohit; Almén, Markus Sällman; Williams, Michael J. et al.

Part of BMC Evolutionary Biology, 2014

• DOI for The GPCR repertoire in the demosponge Amphimedon queenslandica: insights into the GPCR system at the early divergence of animals
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Acute sleep deprivation in healthy young men: Impact on population diversity and function of circulating neutrophils

Christoffersson, Gustaf; Vågesjö, Evelina; Pettersson, Ulrika S.; Massena, Sara et al.

Part of Brain, behavior, and immunity, p. 162-172, 2014

• DOI for Acute sleep deprivation in healthy young men: Impact on population diversity and function of circulating neutrophils

Watching TV and Food Intake: The Role of Content

Chapman, Colin D.; Nilsson, Victor C.; Thune, Hanna A.; Cedernaes, Jonathan et al.

Part of PLOS ONE, 2014

• DOI for Watching TV and Food Intake: The Role of Content
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Acute sleep deprivation increases serum levels of neuron-specific enolase (NSE) and S100 calcium binding protein B (S-100B) in healthy young men

Benedict, Christian; Cedernaes, Jonathan; Giedraitis, Vilmantas; Nilsson, Emil K et al.

Part of Sleep, p. 195-198, 2014

• DOI for Acute sleep deprivation increases serum levels of neuron-specific enolase (NSE) and S100 calcium binding protein B (S-100B) in healthy young men

Late-life alcohol consumption and cognitive function in elderly men

Hogenkamp, Pleunie S.; Benedict, Christian; Sjögren, Per; Kilander, Lena et al.

Part of Age (Omaha), p. 243-249, 2014

• DOI for Late-life alcohol consumption and cognitive function in elderly men

Efficacy of antibody-based therapies to treat Alzheimer's disease: Just a matter of timing?

Cedernaes, Jonathan; Schiöth, Helgi B.; Benedict, Christian

Part of Experimental Gerontology, p. 104-106, 2014

• DOI for Efficacy of antibody-based therapies to treat Alzheimer's disease: Just a matter of timing?

Obesity-linked homologues TfAP-2 and Twz establish meal frequency in Drosophila melanogaster

Williams, Michael; Goergen, Philip; Rajendran, Jayasimman; Zheleznyakova, Galina et al.

Part of PLOS Genetics, 2014

• DOI for Obesity-linked homologues TfAP-2 and Twz establish meal frequency in Drosophila melanogaster
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BDNF polymorphisms are linked to poorer working memory performance, reduced cerebellar and hippocampal volumes and differences in prefrontal cortex in a Swedish elderly population

Brooks, Samantha J; Nilsson, Emil K; Jacobsson, Josefin A; Stein, Dan J et al.

Part of PLOS ONE, 2014

• DOI for BDNF polymorphisms are linked to poorer working memory performance, reduced cerebellar and hippocampal volumes and differences in prefrontal cortex in a Swedish elderly population
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Obsessive-compulsivity and working memory are associated with differential prefrontal cortex and insula activation in adolescents with a recent diagnosis of an eating disorder

Brooks, Samantha J; Solstrand Dahlberg, Linda; Swenne, Ingemar; Aronsson, Marianne et al.

Part of Psychiatry Research, p. 246-253, 2014

• DOI for Obsessive-compulsivity and working memory are associated with differential prefrontal cortex and insula activation in adolescents with a recent diagnosis of an eating disorder

The G protein-coupled receptor GPR162 is widely distributed in the CNS and highly expressed in the hypothalamus and in hedonic feeding areas

Caruso, Vanni; Hägglund, Maria G.; Badiali, Luca; Bagchi, Sonchita et al.

Part of Gene, p. 1-6, 2014

• DOI for The G protein-coupled receptor GPR162 is widely distributed in the CNS and highly expressed in the hypothalamus and in hedonic feeding areas

Exposure to a high-fat high-sugar diet causes strong up-regulation of proopiomelanocortin and differentially affects dopamine D1 and D2 receptor gene expression in the brainstem of rats

Alsiö, Johan; Rask-Andersen, Mathias; Chavan, Rohit A.; Olszewski, Pawel K. et al.

Part of Neuroscience Letters, p. 18-23, 2014

• DOI for Exposure to a high-fat high-sugar diet causes strong up-regulation of proopiomelanocortin and differentially affects dopamine D1 and D2 receptor gene expression in the brainstem of rats

CDKAL1-Related Single Nucleotide Polymorphisms Are Associated with Insulin Resistance in a Cross-Sectional Cohort of Greek Children

Rask-Andersen, Mathias; Philippot, Gaetan; Moschonis, George; Dedoussis, George et al.

Part of PLOS ONE, 2014

• DOI for CDKAL1-Related Single Nucleotide Polymorphisms Are Associated with Insulin Resistance in a Cross-Sectional Cohort of Greek Children
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Insights into the Origin of Nematode Chemosensory GPCRs: Putative Orthologs of the Srw Family Are Found across Several Phyla of Protostomes

Krishnan, Arunkumar; Almén, Markus Sällman; Fredriksson, Robert; Schiöth, Helgi B.

Part of PLOS ONE, 2014

• DOI for Insights into the Origin of Nematode Chemosensory GPCRs: Putative Orthologs of the Srw Family Are Found across Several Phyla of Protostomes
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The Drosophila Kctd-family homologue Kctd12-like modulates male aggression and mating behaviour

Williams, Michael J.; Goergen, Philip; Phad, Ganesh; Fredriksson, Robert et al.

Part of European Journal of Neuroscience, p. 2513-2526, 2014

• DOI for The Drosophila Kctd-family homologue Kctd12-like modulates male aggression and mating behaviour

New functions and signaling mechanisms for the class of adhesion G protein-coupled receptors

Liebscher, Ines; Ackley, Brian; Araç, Demet; Ariestanti, Donna M et al.

Part of Annals of the New York Academy of Sciences, p. 43-64, 2014

• DOI for New functions and signaling mechanisms for the class of adhesion G protein-coupled receptors

Subliminal versus supraliminal stimuli activate neural responses in anterior cingulate cortex, fusiform gyrus and insula: a meta-analysis of fMRI studies

Meneguzzo, Paolo; Tsakiris, Manos; Schiöth, Helgi B.; Stein, Dan J et al.

Part of BMC Psychology, 2014

• DOI for Subliminal versus supraliminal stimuli activate neural responses in anterior cingulate cortex, fusiform gyrus and insula: a meta-analysis of fMRI studies

Melanocortin 4 receptor activation inhibits presynaptic N-type calcium channels in amygdaloid complex neurons

Agosti, Francina; Lopez Soto, Eduardo J.; Cabral, Agustina; Castrogiovanni, Daniel et al.

Part of European Journal of Neuroscience, p. 2755-2765, 2014

• DOI for Melanocortin 4 receptor activation inhibits presynaptic N-type calcium channels in amygdaloid complex neurons

The Drosophila Small GTPase Rac2 is Required for Normal Feeding and Mating Behaviour.

Goergen, Philip; Kasagiannis, Anna; Schiöth, Helgi B; Williams, Michael J

Part of Behavior Genetics, p. 155-64, 2014

• DOI for The Drosophila Small GTPase Rac2 is Required for Normal Feeding and Mating Behaviour.

Replacement of short segments within transmembrane domains of MC2R disrupts retention signal

Fridmanis, Davids; Petrovska, Ramona; Pjanova, Dace; Schiöth, Helgi B. et al.

Part of Journal of Molecular Endocrinology, p. 201-215, 2014

• DOI for Replacement of short segments within transmembrane domains of MC2R disrupts retention signal

The role of common and rare MC4R variants and FTO polymorphisms in extreme form of obesity

Rovite, Vita; Petrovska, Ramona; Vaivade, Iveta; Kalnina, Ineta et al.

Part of Molecular Biology Reports, p. 1491-500, 2014

• DOI for The role of common and rare MC4R variants and FTO polymorphisms in extreme form of obesity

Exposure to Bisphenol A Affects Lipid Metabolism in Drosophila melanogaster

Williams, Michael J; Wang, Yi; Klockars, Anica; Lind, Monica et al.

Part of Basic & Clinical Pharmacology & Toxicology, p. 414-420, 2014

• DOI for Exposure to Bisphenol A Affects Lipid Metabolism in Drosophila melanogaster

Regulation of aggression by obesity-linked genes TfAP-2 and Twz through octopamine signaling in Drosophila

Williams, Michael J; Goergen, Philip; Rajendran, Jayasimman; Klockars, Anica et al.

Part of Genetics, p. 349-362, 2014

• DOI for Regulation of aggression by obesity-linked genes TfAP-2 and Twz through octopamine signaling in Drosophila

The druggable genome: Evaluation of drug targets in clinical trials suggests major shifts in molecular class and indication

Rask-Andersen, Mathias; Masuram, Surendar; Schiöth, Helgi B

Part of Annual Review of Pharmacology and Toxicology, p. 9-26, 2014

• DOI for The druggable genome: Evaluation of drug targets in clinical trials suggests major shifts in molecular class and indication

Calorie anticipation alters food intake after low-caloric but not high-caloric preloads

Hogenkamp, Pleunie; Cedernaes, Jonathan; Chapman, Colin; Vogel, Heike et al.

Part of Obesity, p. 1548-1553, 2013

• DOI for Calorie anticipation alters food intake after low-caloric but not high-caloric preloads
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Adipose tissue stearoyl-CoA desaturase 1 index is increased and linoleic acid is decreased in obesity-prone rats fed a high-fat diet

Cedernaes, Jonathan; Alsiö, Johan; Västermark, Åke; Risérus, Ulf et al.

Part of Lipids in Health and Disease, 2013

• DOI for Adipose tissue stearoyl-CoA desaturase 1 index is increased and linoleic acid is decreased in obesity-prone rats fed a high-fat diet

Characterization of the transporterB⁰AT3 (Slc6a17) in the rodent central nervous system

Hägglund, Maria G. A.; Hellsten, Sofie V.; Bagchi, Sonchita; Ljungdahl, Anna et al.

Part of BMC Neuroscience, p. 54, 2013

• DOI for Characterization of the transporterB⁰AT3 (Slc6a17) in the rodent central nervous system
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Anorexia nervosa is linked to reduced brain structure in reward and somatosensory regions: a meta-analysis of VBM studies

Titova, Olga E; Hjorth, Olof C; Schiöth, Helgi B.; Brooks, Samantha J

Part of BMC Psychiatry, p. 110, 2013

• DOI for Anorexia nervosa is linked to reduced brain structure in reward and somatosensory regions: a meta-analysis of VBM studies
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Mediterranean diet habits in older individuals: Associations with cognitive functioning and brain volumes

Titova, Olga E; Ax, Erika; Brooks, Samantha J; Sjögren, Per et al.

Part of Experimental Gerontology, p. 1443-1448, 2013

• DOI for Mediterranean diet habits in older individuals: Associations with cognitive functioning and brain volumes

Dietary intake of eicosapentaenoic and docosahexaenoic acids is linked to gray matter volume and cognitive function in elderly

Titova, Olga E; Sjögren, Per; Brooks, Samantha J; Kullberg, Joel et al.

Part of Age (Omaha), p. 1495-1505, 2013

• DOI for Dietary intake of eicosapentaenoic and docosahexaenoic acids is linked to gray matter volume and cognitive function in elderly

Acute sleep deprivation increases portion size and affects food choice in young men

Hogenkamp, Pleunie S; Nilsson, Emil; Nilsson, Victor C; Chapman, Colin D et al.

Part of Psychoneuroendocrinology, p. 1668-1674, 2013

• DOI for Acute sleep deprivation increases portion size and affects food choice in young men

Acute sleep deprivation increases food purchasing in men

Chapman, Colin D.; Nilsson, Emil K.; Nilsson, Victor C.; Cedernaes, Jonathan et al.

Part of Obesity, 2013

• DOI for Acute sleep deprivation increases food purchasing in men

Late-life obesity is associated with smaller global and regional gray matter volumes: a voxel-based morphometric study

Brooks, Samantha J; Benedict, Christian; Burgos, J; Kempton, M J et al.

Part of International Journal of Obesity, p. 230-236, 2013

• DOI for Late-life obesity is associated with smaller global and regional gray matter volumes: a voxel-based morphometric study

Growth Hormone-Releasing Hormone Improves Cognitive Function in Older Adults: Sleep On It

Benedict, Christian; Chapman, Colin D; Schiöth, Helgi B

Part of JAMA neurology, p. 529-530, 2013

• DOI for Growth Hormone-Releasing Hormone Improves Cognitive Function in Older Adults: Sleep On It

Association between physical activity and brain health in older adults

Benedict, Christian; Brooks, Samantha J; Kullberg, Joel; Nordenskjöld, Richard et al.

Part of Neurobiology of Aging, p. 83-90, 2013

• DOI for Association between physical activity and brain health in older adults

Sweet taste perception not altered after acute sleep deprivation in healthy young men

Hogenkamp, Pleunie S; Nilsson, Emil; Chapman, C D; Cedernaes, Jonathan et al.

Part of Somnologie, p. 111-114, 2013

• DOI for Sweet taste perception not altered after acute sleep deprivation in healthy young men

Genome-wide analysis shows association of epigenetic changes in regulators of Rab and Rho GTPases with spinal muscular atrophy severity

Zheleznyakova, Galina Y.; Voisin, Sarah; Kiselev, Anton V.; Almén, Markus Sällman et al.

Part of European Journal of Human Genetics, p. 988-993, 2013

• DOI for Genome-wide analysis shows association of epigenetic changes in regulators of Rab and Rho GTPases with spinal muscular atrophy severity

Involvement of the Neutral Amino Acid Transporter SLC6A15 and Leucine in Obesity-Related Phenotypes

Drgonova, Jana; Jacobsson, Josefin A.; Han, Joan C.; Yanovski, Jack A. et al.

Part of PLOS ONE, 2013

• DOI for Involvement of the Neutral Amino Acid Transporter SLC6A15 and Leucine in Obesity-Related Phenotypes
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Increased prefrontal and parahippocampal activation with reduced dorsolateral prefrontal and insular cortex activation to food images in obesity: a meta-analysis of fMRI studies.

Brooks, Samantha J; Cedernaes, Jonathan; Schiöth, Helgi B

Part of PLOS ONE, 2013

• DOI for Increased prefrontal and parahippocampal activation with reduced dorsolateral prefrontal and insular cortex activation to food images in obesity: a meta-analysis of fMRI studies.
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B(0)AT2 (SLC6A15) is localized to neurons and astrocytes, and is involved in mediating the effect of leucine in the brain

Hägglund, Maria G A; Roshanbin, Sahar; Löfqvist, Erik; Hellsten, Sofie V et al.

Part of PLOS ONE, 2013

• DOI for B(0)AT2 (SLC6A15) is localized to neurons and astrocytes, and is involved in mediating the effect of leucine in the brain
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The STK33-linked SNP rs4929949 is associated with obesity and BMI in two independent cohorts of Swedish and Greek children

Rask-Andersen, Mathias; Moschonis, George; Chrousos, George; Marcus, Claude et al.

Part of PLOS ONE, 2013

• DOI for The STK33-linked SNP rs4929949 is associated with obesity and BMI in two independent cohorts of Swedish and Greek children
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Effect of oral processing behaviour on food intake and satiety

Hogenkamp, Pleunie S.; Schiöth, Helgi B.

Part of Trends in Food Science & Technology, p. 67-75, 2013

• DOI for Effect of oral processing behaviour on food intake and satiety

Early vertebrate origin of melanocortin 2 receptor accessory proteins (MRAPs)

Valsalan, Ravisankar; Krishnan, Arunkumar; Almén, Markus Sällman; Fredriksson, Robert et al.

Part of General and Comparative Endocrinology, p. 123-132, 2013

• DOI for Early vertebrate origin of melanocortin 2 receptor accessory proteins (MRAPs)

Remarkable similarities between the hemichordate (Saccoglossus kowalevskii) and vertebrate GPCR repertoire

Krishnan, Arunkumar; Almén, Markus Sällman; Fredriksson, Robert; Schiöth, Helgi B.

Part of Gene, p. 122-133, 2013

• DOI for Remarkable similarities between the hemichordate (Saccoglossus kowalevskii) and vertebrate GPCR repertoire

Determination of the obesity-associated gene variants within the entire FTO gene by ultra-deep targeted sequencing in obese and lean children.

Sällman Almén, Markus; Rask-Andersen, Mathias; Jacobsson, Josefin A; Ameur, Adam et al.

Part of International Journal of Obesity, p. 424-431, 2013

• DOI for Determination of the obesity-associated gene variants within the entire FTO gene by ultra-deep targeted sequencing in obese and lean children.

Molecular mechanisms involved in interleukin 1-beta (IL-1 beta)-induced memory impairment. Modulation by alpha-melanocyte-stimulating hormone (alpha-MSH)

Gonzalez, P.; Machado, I.; Vilcaes, A.; Caruso, C. et al.

Part of Brain, behavior, and immunity, p. 141-150, 2013

• DOI for Molecular mechanisms involved in interleukin 1-beta (IL-1 beta)-induced memory impairment. Modulation by alpha-melanocyte-stimulating hormone (alpha-MSH)

Polymorphisms in FTO and near TMEM18 associate with type 2 diabetes and predispose to younger age at diagnosis of diabetes

Kalnina, Ineta; Zaharenko, Linda; Vaivade, Iveta; Rovite, Vita et al.

Part of Gene, p. 462-468, 2013

• DOI for Polymorphisms in FTO and near TMEM18 associate with type 2 diabetes and predispose to younger age at diagnosis of diabetes

Insulin receptor-like ectodomain genes and splice variants are found in both arthropods and human brain cDNA

Vastermark, Åke; Rask-Andersen, Mathias; Sawant, Rahul S.; Reiter, Jill L. et al.

Part of Journal of Systematics and Evolution, p. 664-670, 2013

• DOI for Insulin receptor-like ectodomain genes and splice variants are found in both arthropods and human brain cDNA

Adhesion GPCRs are widely expressed throughout the subsections of the gastrointestinal tract

Badiali, Luca; Cedernaes, Jonathan; Olszewski, Pawel K; Nylander, Olof et al.

Part of BMC Gastroenterology, p. 134, 2012

• DOI for Adhesion GPCRs are widely expressed throughout the subsections of the gastrointestinal tract
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A debate on current eating disorder diagnoses in light of neurobiological findings: is it time for a spectrum model?

Brooks, Samantha Jane; Rask-Andersen, Mathias; Benedict, Christian; Schiöth, Helgi Birgir

Part of BMC Psychiatry, p. 76, 2012

• DOI for A debate on current eating disorder diagnoses in light of neurobiological findings: is it time for a spectrum model?
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The MAP2K5-linked SNP rs2241423 is associated with BMI and obesity in two cohorts of Swedish and Greek children

Rask-Andersen, Mathias; Jacobsson, Josefin A.; Moschonis, George; Ek, Anna E. et al.

Part of BMC Medical Genetics, p. 36, 2012

• DOI for The MAP2K5-linked SNP rs2241423 is associated with BMI and obesity in two cohorts of Swedish and Greek children
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Acute sleep deprivation has no lasting effects on the human antibody titer response following a novel influenza A H1N1 virus vaccination

Benedict, Christian; Brytting, Maria; Markström, Agneta; Broman, Jan-Erik et al.

Part of BMC Immunology, p. 1, 2012

• DOI for Acute sleep deprivation has no lasting effects on the human antibody titer response following a novel influenza A H1N1 virus vaccination
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Diurnal Rhythm of Circulating Nicotinamide Phosphoribosyltransferase (Nampt/Visfatin/PBEF): Impact of Sleep Loss and Relation to Glucose Metabolism

Benedict, Christian; Shostak, Anton; Lange, Tanja; Brooks, Samantha J et al.

Part of Journal of Clinical Endocrinology and Metabolism, 2012

• DOI for Diurnal Rhythm of Circulating Nicotinamide Phosphoribosyltransferase (Nampt/Visfatin/PBEF): Impact of Sleep Loss and Relation to Glucose Metabolism

Lifestyle determinants of the drive to eat: a meta-analysis

Chapman, Colin Daniel; Benedict, Christian; Brooks, Samantha Jane; Schiöth, Helgi Birgir

Part of American Journal of Clinical Nutrition, p. 492-497, 2012

• DOI for Lifestyle determinants of the drive to eat: a meta-analysis

Impaired Insulin Sensitivity as Indexed by the HOMA Score Is Associated With Deficits in Verbal Fluency and Temporal Lobe Gray Matter Volume in the Elderly

Benedict, Christian; Brooks, Samantha J; Kullberg, Joel; Burgos, Jonathan et al.

Part of Diabetes Care, p. 488-494, 2012

• DOI for Impaired Insulin Sensitivity as Indexed by the HOMA Score Is Associated With Deficits in Verbal Fluency and Temporal Lobe Gray Matter Volume in the Elderly

Healthcare systems never sleep: are medical residents today the patients of tomorrow?

Schiöth, Helgi Birgir; Brooks, Samantha Jane; Benedict, Christian

Part of Sleep Medicine, p. 965-965, 2012

• DOI for Healthcare systems never sleep: are medical residents today the patients of tomorrow?

Genome wide analysis reveals association of a FTO gene variant with epigenetic changes

Almén, Markus Sällman; Jacobsson, Josefin A.; Moschonis, George; Benedict, Christian et al.

Part of Genomics, p. 132-137, 2012

• DOI for Genome wide analysis reveals association of a FTO gene variant with epigenetic changes

Acute Sleep Deprivation Enhances the Brain's Response to Hedonic Food Stimuli: An fMRI Study

Benedict, Christian; Brooks, Samantha J; O'Daly, Owen G; Almèn, Markus S et al.

Part of Journal of Clinical Endocrinology and Metabolism, 2012

• DOI for Acute Sleep Deprivation Enhances the Brain's Response to Hedonic Food Stimuli: An fMRI Study

Brain Insulin Signaling and Alzheimer's Disease: Current Evidence and Future Directions

Schiöth, Helgi B.; Craft, Suzanne; Brooks, Samantha J.; Frey, William H. et al.

Part of Molecular Neurobiology, p. 4-10, 2012

• DOI for Brain Insulin Signaling and Alzheimer's Disease: Current Evidence and Future Directions

The influence of active and passive smoking during pregnancy on umbilical cord blood levels of vitamins A and E and neonatal anthropometric indices

Titova, Olga E.; Ayvazova, Elena A.; Bichkaeva, Fatima A.; Brooks, Samantha J. et al.

Part of British Journal of Nutrition, p. 1341-1345, 2012

• DOI for The influence of active and passive smoking during pregnancy on umbilical cord blood levels of vitamins A and E and neonatal anthropometric indices

To Sleep or Not To Sleep: Do We Forget Our Patient's Sleep?

Schiöth, Helgi Birgir; Chapman, Colin Daniel; Benedict, Christian

Part of Archives of Internal Medicine, p. 746-746, 2012

• DOI for To Sleep or Not To Sleep: Do We Forget Our Patient's Sleep?

Association of TMEM18 variants with BMI and waist circumference in children and correlation of mRNA expression in the PFC with body weight in rats

Rask-Andersen, Mathias; Jacobsson, Josefin A.; Moschonis, George; Chavan, Rohit A. et al.

Part of European Journal of Human Genetics, p. 192-197, 2012

• DOI for Association of TMEM18 variants with BMI and waist circumference in children and correlation of mRNA expression in the PFC with body weight in rats

Neurobeachin, a Regulator of Synaptic Protein Targeting, Is Associated with Body Fat Mass and Feeding Behavior in Mice and Body-Mass Index in Humans

Olszewski, Pawel K.; Rozman, Jan; Jacobsson, Josefin A.; Rathkolb, Birgit et al.

Part of PLoS Genetics, 2012

• DOI for Neurobeachin, a Regulator of Synaptic Protein Targeting, Is Associated with Body Fat Mass and Feeding Behavior in Mice and Body-Mass Index in Humans
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Thinking about Eating Food Activates Visual Cortex with Reduced Bilateral Cerebellar Activation in Females with Anorexia Nervosa: An fMRI Study

Brooks, Samantha J.; O'Daly, Owen; Uher, Rudolf; Friederich, Hans-Christoph et al.

Part of PLOS ONE, 2012

• DOI for Thinking about Eating Food Activates Visual Cortex with Reduced Bilateral Cerebellar Activation in Females with Anorexia Nervosa: An fMRI Study
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The Origin of GPCRs: Identification of Mammalian like Rhodopsin, Adhesion, Glutamate and Frizzled GPCRs in Fungi

Krishnan, Arunkumar; Sällaman Almén, Markus; Fredriksson, Robert; Schiöth, Helgi B

Part of PLOS ONE, 2012

• DOI for The Origin of GPCRs: Identification of Mammalian like Rhodopsin, Adhesion, Glutamate and Frizzled GPCRs in Fungi
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The Dispanins: A Novel Gene Family of Ancient Origin That Contains 14 Human Members

Sällman Almén, Markus; Bringeland, Nathalie; Fredriksson, Robert; Schiöth, Helgi B.

Part of PLOS ONE, 2012

• DOI for The Dispanins: A Novel Gene Family of Ancient Origin That Contains 14 Human Members
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Identification of Distant Agouti-Like Sequences and Re-Evaluation of the Evolutionary History of the Agouti-Related Peptide (AgRP)

Västermark, Åke; Krishnan, Arunkumar; Houle, Michael E.; Fredriksson, Robert et al.

Part of PLOS ONE, 2012

• DOI for Identification of Distant Agouti-Like Sequences and Re-Evaluation of the Evolutionary History of the Agouti-Related Peptide (AgRP)
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Polymorphisms in sh2b1 and spns1 loci are associated with triglyceride levels in a healthy population in northern Sweden

Västermark, Åke; Jacobsson, Josefin; Johansson, Åsa; Fredriksson, Robert et al.

Part of Journal of Genetics, p. 237-240, 2012

• DOI for Polymorphisms in sh2b1 and spns1 loci are associated with triglyceride levels in a healthy population in northern Sweden

Genetic variants near the MGAT1 gene are associated with body weight, BMI and fatty acid metabolism among adults and children

Jacobsson, Josefin; Rask-Andersen, Mathias; Risérus, Ulf; Moschonis, G et al.

Part of International Journal of Obesity, p. 119-129, 2012

• DOI for Genetic variants near the MGAT1 gene are associated with body weight, BMI and fatty acid metabolism among adults and children

Identification and analysis of functionally important amino acids in human purinergic 12 receptor using a Saccharomyces cerevisiae expression system

Ignatovica, Vita; Megnis, Kaspars; Lapins, Maris; Schiöth, Helgi B et al.

Part of The FEBS Journal, p. 180-191, 2012

• DOI for Identification and analysis of functionally important amino acids in human purinergic 12 receptor using a Saccharomyces cerevisiae expression system

Differential effects of fluoxetine and venlafaxine on memory recognition: Possible mechanisms of action

Paola Carlini, Valeria; Belen Poretti, Maria; Rask-Andersen, Mathias; Chavan, Rohit A. et al.

Part of Progress in Neuro-psychopharmacology and Biological Psychiatry, p. 159-167, 2012

• DOI for Differential effects of fluoxetine and venlafaxine on memory recognition: Possible mechanisms of action

Acute ghrelin administration reverses depressive-like behavior induced by bilateral olfactory bulbectomy in mice

Paola Carlini, Valeria; Machado, Daniele Guilhermano; Buteler, Florencia; Ghersi, Marisa et al.

Part of Peptides, p. 160-165, 2012

• DOI for Acute ghrelin administration reverses depressive-like behavior induced by bilateral olfactory bulbectomy in mice

Subliminal food images compromise superior working memory performance in women with restricting anorexia nervosa

Brooks, Samantha J.; O'Daly, Owen G.; Uher, Rudolf; Schiöth, Helgi B. et al.

Part of Consciousness and Cognition, p. 751-763, 2012

• DOI for Subliminal food images compromise superior working memory performance in women with restricting anorexia nervosa

Expression levels of genes encoding melanin concentrating hormone (MCH) and MCH receptor change in taste aversion, but MCH injections do not alleviate aversive responses

Mitra, Anaya; Klockars, Anica; Gosnell, Blake A.; Le Grevés, Madeleine et al.

Part of Pharmacology, Biochemistry and Behavior, p. 581-586, 2012

• DOI for Expression levels of genes encoding melanin concentrating hormone (MCH) and MCH receptor change in taste aversion, but MCH injections do not alleviate aversive responses

Single nucleotide polymorphisms of the purinergic 1 receptor are not associated with myocardial infarction in a Latvian population

Ignatovica, Vita; Latkovskis, Gustavs; Peculis, Raitis; Megnis, Kaspars et al.

Part of Molecular Biology Reports, p. 1917-1925, 2012

• DOI for Single nucleotide polymorphisms of the purinergic 1 receptor are not associated with myocardial infarction in a Latvian population

Dissecting signaling and functions of adhesion G protein-coupled receptors

Araç, Demet; Aust, Gabriela; Calebiro, Davide; Engel, Felix B et al.

Part of Annals of the New York Academy of Sciences, p. 1-25, 2012

• DOI for Dissecting signaling and functions of adhesion G protein-coupled receptors

Genetic and expression studies of SMN2 gene in Russian patients with spinal muscular atrophy type II and III

Zheleznyakova, Galina Yu; Kiselev, Anton V.; Vakharlovsky, Viktor G.; Rask-Andersen, Mathias et al.

Part of BMC Medical Genetics, p. 96, 2011

• DOI for Genetic and expression studies of SMN2 gene in Russian patients with spinal muscular atrophy type II and III

Functional coupling analysis suggests link between the obesity gene FTO and the BDNF-NTRK2 signaling pathway

Rask-Andersen, Mathias; Sällman Almén, Markus; Olausen, Hans R.; Olszewski, Pawel K. et al.

Part of BMC Neuroscience, p. 117, 2011

• DOI for Functional coupling analysis suggests link between the obesity gene FTO and the BDNF-NTRK2 signaling pathway
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Restraint of appetite and reduced regional brain volumes in anorexia nervosa: a voxel-based morphometric study

Brooks, Samantha J; Barker, Gareth J; O'Daly, Owen G; Brammer, Michael et al.

Part of BMC Psychiatry, p. 179, 2011

• DOI for Restraint of appetite and reduced regional brain volumes in anorexia nervosa: a voxel-based morphometric study
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Functional specialization in nucleotide sugar transporters occurred through differentiation of the gene cluster EamA (DUF6) before the radiation of Viridiplantae

Västermark, Åke; Almén, Markus Sällman; Simmen, Martin W.; Fredriksson, Robert et al.

Part of BMC Evolutionary Biology, p. 123, 2011

• DOI for Functional specialization in nucleotide sugar transporters occurred through differentiation of the gene cluster EamA (DUF6) before the radiation of Viridiplantae

The fat mass and obesity gene is linked to reduced verbal fluency in overweight and obese elderly men

Benedict, Christian; Jacobsson, Josefin A; Rönnemaa, Elina; Sällman Almén, Markus et al.

Part of Neurobiology of Aging, p. 11590-115900000, 2011

• DOI for The fat mass and obesity gene is linked to reduced verbal fluency in overweight and obese elderly men

Intranasal insulin as a therapeutic option in the treatment of cognitive impairments

Benedict, Christian; Frey, William H.; Schiöth, Helgi; Schultes, Bernd et al.

Part of Experimental Gerontology, p. 112-115, 2011

• DOI for Intranasal insulin as a therapeutic option in the treatment of cognitive impairments

Intranasal Insulin Enhances Postprandial Thermogenesis and Lowers Postprandial Serum Insulin Levels in Healthy Men

Benedict, Christian; Brede, Swantje; Schiöth, Helgi; Lehnert, Hendrik et al.

Part of Diabetes, p. 114-118, 2011

• DOI for Intranasal Insulin Enhances Postprandial Thermogenesis and Lowers Postprandial Serum Insulin Levels in Healthy Men

Acute sleep deprivation reduces energy expenditure in healthy men

Benedict, Christian; Hallschmid, Manfred; Lassen, Arne; Mahnke, Christin et al.

Part of American Journal of Clinical Nutrition, p. 1229-1236, 2011

• DOI for Acute sleep deprivation reduces energy expenditure in healthy men

Detailed Analysis of Variants in FTO in Association with Body Composition in a Cohort of 70-Year-Olds Suggests a Weakened Effect among Elderly

Jacobsson, Josefin A.; Sällman Almén, Markus; Benedict, Christian; Hedberg, Lilia A. et al.

Part of PLOS ONE, 2011

• DOI for Detailed Analysis of Variants in FTO in Association with Body Composition in a Cohort of 70-Year-Olds Suggests a Weakened Effect among Elderly

The solute carrier families have a remarkably long evolutionary history with the majority of the human families present before divergence of Bilaterian species

Höglund, Pär J.; Nordström, Karl J. V.; Schiöth, Helgi B.; Fredriksson, Robert

Part of Molecular biology and evolution, p. 1531-1541, 2011

• DOI for The solute carrier families have a remarkably long evolutionary history with the majority of the human families present before divergence of Bilaterian species

Comprehensive analysis of localization of 78 solute carrier genes throughout the subsections of the rat gastrointestinal tract

Cedernaes, Jonathan; Olszewski, Pawel K.; Sällman Almén, Markus; Stephansson, Olga et al.

Part of Biochemical and Biophysical Research Communications - BBRC, p. 702-707, 2011

• DOI for Comprehensive analysis of localization of 78 solute carrier genes throughout the subsections of the rat gastrointestinal tract

Long evolutionary conservation and considerable tissue specificity of several atypical solute carrier transporters

Sreedharan, Smitha; Stephansson, Olga; Schiöth, Helgi B.; Fredriksson, Robert

Part of Gene, p. 11-18, 2011

• DOI for Long evolutionary conservation and considerable tissue specificity of several atypical solute carrier transporters

Fto colocalizes with a satiety mediator oxytocin in the brain and upregulates oxytocin gene expression

Olszewski, Pawel K.; Fredriksson, Robert; Eriksson, Jenny D.; Mitra, Anaya et al.

Part of Biochemical and Biophysical Research Communications - BBRC, p. 422-426, 2011

• DOI for Fto colocalizes with a satiety mediator oxytocin in the brain and upregulates oxytocin gene expression

Independent HHsearch, Needleman-Wunsch-based, and motif analyses reveal the overall hierarchy for most of the G protein-coupled receptor families

Nordström, Karl; Sällman Almén, Markus; Edstam, Monika; Fredriksson, Robert et al.

Part of Molecular biology and evolution, p. 2471-2480, 2011

• DOI for Independent HHsearch, Needleman-Wunsch-based, and motif analyses reveal the overall hierarchy for most of the G protein-coupled receptor families

Trends in the exploitation of novel drug targets

Rask-Andersen, Mathias; Sällman Almén, Markus; Schiöth, Helgi B.

Part of Nature reviews. Drug discovery, p. 579-590, 2011

• DOI for Trends in the exploitation of novel drug targets

Differential Neural Responses to Food Images in Women with Bulimia versus Anorexia Nervosa

Brooks, Samantha J.; O'Daly, Owen G.; Uher, Rudolf; Friederich, Hans-Christoph et al.

Part of PLOS ONE, 2011

• DOI for Differential Neural Responses to Food Images in Women with Bulimia versus Anorexia Nervosa

Fto immunoreactivity is widespread in the rodent brain and abundant in feeding-related sites, but the number of Fto-positive cells is not affected by changes in energy balance

Olszewski, Pawel K.; Radomska, Katarzyna J.; Ghimire, Kedar; Klockars, Anica et al.

Part of Physiology and Behavior, p. 248-253, 2011

• DOI for Fto immunoreactivity is widespread in the rodent brain and abundant in feeding-related sites, but the number of Fto-positive cells is not affected by changes in energy balance

Independent HHsearch, Needleman-Wunsch-based, and motif analyses reveal the overall hierarchy for most of the G protein-coupled receptor families

Nordström, Karl; Sällman Almén, Markus; Edstam, Monika; Fredriksson, Robert et al.

Part of Molecular biology and evolution, p. 2471-2480, 2011

The early origin of melanocortin receptors, agouti-related peptide, agouti signalling peptide, and melanocortin receptor-accessory proteins, with emphasis on pufferfishes, elephant shark, lampreys, and amphioxus

Västermark, Åke; Schiöth, Helgi B

Part of European Journal of Pharmacology, p. 61-69, 2011

• DOI for The early origin of melanocortin receptors, agouti-related peptide, agouti signalling peptide, and melanocortin receptor-accessory proteins, with emphasis on pufferfishes, elephant shark, lampreys, and amphioxus

Melanocortin receptor subtypes in interrenal cells and corticotropic activity of α-melanocyte-stimulating hormones in barfin flounder, Verasper moseri

Kobayashi, Yuki; Chiba, Hiroaki; Yamanome, Takeshi; Schiöth, Helgi B. et al.

Part of General and Comparative Endocrinology, p. 558-568, 2011

• DOI for Melanocortin receptor subtypes in interrenal cells and corticotropic activity of α-melanocyte-stimulating hormones in barfin flounder, Verasper moseri

Associations between severity of obesity in childhood and adolescence, obesity onset andparental BMI: a longitudinal cohort study

Svensson, Viktoria; Jacobsson, Josefin A; Fredriksson, Robert; Danielsson, Pernilla et al.

Part of International Journal of Obesity, p. 46-52, 2011

• DOI for Associations between severity of obesity in childhood and adolescence, obesity onset andparental BMI: a longitudinal cohort study

Reply to Braasch and Postlethwait: Evolutionary origin of the teleost A2 agouti genes (agouti signaling protein 2 and agouti-related protein 2) remains unclear

Schiöth, Helgi B.; Västermark, Åke; Cone, Roger D.

Part of Proceedings of the National Academy of Sciences of the United States of America, 2011

• DOI for Reply to Braasch and Postlethwait: Evolutionary origin of the teleost A2 agouti genes (agouti signaling protein 2 and agouti-related protein 2) remains unclear

Opioids as facilitators of feeding: Can any food be rewarding?

Olszewski, Pawel K.; Alsiö, Johan; Schiöth, Helgi B.; Levine, Allen S.

Part of Physiology and Behavior, p. 105-110, 2011

• DOI for Opioids as facilitators of feeding: Can any food be rewarding?

The G protein coupled receptor Gpr153 shares common evolutionary origin with Gpr162 and is highly expressed in central regions including the thalamus, cerebellum and the arcuate nucleus

Sreedharan, Smitha; Sällman Almén, Markus; Carlini, Valeria P; Haitina, Tatjana et al.

Part of The FEBS Journal, p. 4881-4894, 2011

• DOI for The G protein coupled receptor Gpr153 shares common evolutionary origin with Gpr162 and is highly expressed in central regions including the thalamus, cerebellum and the arcuate nucleus

Identification of somatostatin receptor type 5 gene polymorphisms associated with acromegaly

Ciganoka, Darja; Balcere, Inga; Kapa, Ivo; Peculis, Raitis et al.

Part of European Journal of Endocrinology, p. 517-525, 2011

• DOI for Identification of somatostatin receptor type 5 gene polymorphisms associated with acromegaly

Hippocampal effects of neuronostatin on memory, anxiety-like behavior and food intake in rats

Carlini, V. P.; Ghersi, M.; Gabach, L.; Schioth, Helgi B. et al.

Part of Neuroscience, p. 145-152, 2011

• DOI for Hippocampal effects of neuronostatin on memory, anxiety-like behavior and food intake in rats

Ghrelin inhibited serotonin release from hippocampal slices

Ghersi, Marisa Soledad; Casas, Sebastian M.; Escudero, Carla; Carlini, Valeria P. et al.

Part of Peptides, p. 2367-2371, 2011

• DOI for Ghrelin inhibited serotonin release from hippocampal slices

SPRIT: Identifying horizontal gene transfer in rooted phylogenetic trees

Hill, Tobias; Nordström, Karl J V; Thollesson, Mikael; Säfström, Tommy M et al.

Part of BMC Evolutionary Biology, p. 42, 2010

• DOI for SPRIT: Identifying horizontal gene transfer in rooted phylogenetic trees

The obesity gene, TMEM18, is of ancient origin, found in majority of neuronal cells in all major brain regions and associated with obesity in severely obese children

Almén, Markus Sällman; Jacobsson, Josefin A.; Shaik, Jafar H. A.; Olszewski, Pawel K. et al.

Part of BMC Medical Genetics, p. 58, 2010

• DOI for The obesity gene, TMEM18, is of ancient origin, found in majority of neuronal cells in all major brain regions and associated with obesity in severely obese children

Glutamate, aspartate and nucleotide transporters in the SLC17 family form four main phylogenetic clusters: evolution and tissue expression

Sreedharan, Smitha; Shaik, Jafar H A; Olszewski, Pawel K; Levine, Allen S et al.

Part of BMC Genomics, p. 17, 2010

• DOI for Glutamate, aspartate and nucleotide transporters in the SLC17 family form four main phylogenetic clusters: evolution and tissue expression

Dopamine D1 receptor gene expression decreases in the nucleus accumbens upon long-term exposure to palatable food and differs depending on diet-induced obesity phenotype in rats

Alsiö, Johan; Olszewski, Pawel K.; Norbäck, A. H.; Gunnarsson, Z. E. A. et al.

Part of Neuroscience, p. 779-787, 2010

• DOI for Dopamine D1 receptor gene expression decreases in the nucleus accumbens upon long-term exposure to palatable food and differs depending on diet-induced obesity phenotype in rats

Molecular, Immunohistochemical, and Pharmacological Evidence of Oxytocin's Role as Inhibitor of Carbohydrate But Not Fat Intake

Olszewski, Pawel K.; Klockars, Anica; Olszewska, Agnieszka M.; Fredriksson, Robert et al.

Part of Endocrinology, p. 4736-4744, 2010

• DOI for Molecular, Immunohistochemical, and Pharmacological Evidence of Oxytocin's Role as Inhibitor of Carbohydrate But Not Fat Intake

Central nociceptin/orphanin FQ system elevates food consumption by both increasing energy intake and reducing aversive responsiveness

Olszewski, Pawel K; Grace, Martha K; Fard, Shahrzad Shirazi; Le Grevès, Madeleine et al.

Part of American Journal of Physiology. Regulatory Integrative and Comparative Physiology, 2010

• DOI for Central nociceptin/orphanin FQ system elevates food consumption by both increasing energy intake and reducing aversive responsiveness

Chronic sugar intake dampens feeding-related activity of neurons synthesizing a satiety mediator, oxytocin

Mitra, Anaya; Gosnell, Blake A; Schiöth, Helgi B.; Grace, Martha K et al.

Part of Peptides, p. 1346-1352, 2010

• DOI for Chronic sugar intake dampens feeding-related activity of neurons synthesizing a satiety mediator, oxytocin

Ghrelin induced memory facilitation implicates nitric oxide synthase activation and decrease in the threshold to promote LTP in hippocampal dentate gyrus

Carlini, Valeria P.; Perez, Mariela F.; Salde, Estela; Schiöth, Helgi B. et al.

Part of Physiology and Behavior, p. 117-123, 2010

• DOI for Ghrelin induced memory facilitation implicates nitric oxide synthase activation and decrease in the threshold to promote LTP in hippocampal dentate gyrus

Differential expressions of melanocortin receptor subtypes in melanophores and xanthophores of barfin flounder

Kobayashi, Yuki; Tsuchiya, Keisuke; Yamanome, Takeshi; Schiöth, Helgi B. et al.

Part of General and Comparative Endocrinology, p. 133-142, 2010

• DOI for Differential expressions of melanocortin receptor subtypes in melanophores and xanthophores of barfin flounder

Identification of domains responsible for specific membrane transport and ligand specificity of the ACTH receptor (MC2R)

Fridmanis, Davids; Petrovska, Ramona; Kalnina, Ineta; Slaidina, Maija et al.

Part of Molecular and Cellular Endocrinology, p. 175-183, 2010

• DOI for Identification of domains responsible for specific membrane transport and ligand specificity of the ACTH receptor (MC2R)

MDMA (Ecstasy) decreases the number of neurons and stem cells in embryonic cortical cultures

Kindlundh-Högberg, Anna M. S.; Pickering, Chris; Wicher, Grzegorz; Hobér, David et al.

Part of Cellular and molecular neurobiology, p. 13-21, 2010

• DOI for MDMA (Ecstasy) decreases the number of neurons and stem cells in embryonic cortical cultures

Ghrelin and memory: differential effects on acquisition and retrieval

Carlini, Valeria P; Ghersi, Marisa; Schiöth, Helgi B; de Barioglio, Susana R

Part of Peptides, p. 1190-1193, 2010

• DOI for Ghrelin and memory: differential effects on acquisition and retrieval

The common FTO variant rs9939609 is not associated with BMI in a longitudinal study on a cohort of Swedish men born 1920-1924

Jacobsson, Josefin A; Risérus, Ulf; Axelsson, Tomas; Lannfelt, Lars et al.

Part of BMC Medical Genetics, p. 131, 2009

• DOI for The common FTO variant rs9939609 is not associated with BMI in a longitudinal study on a cohort of Swedish men born 1920-1924

Association between a rare SNP in the second intron of human Agouti related protein gene and increased BMI

Kalnina, Ineta; Kapa, Ivo; Pirags, Valdis; Ignatovica, Vita et al.

Part of BMC Medical Genetics, p. 63, 2009

• DOI for Association between a rare SNP in the second intron of human Agouti related protein gene and increased BMI

The G protein-coupled receptor subset of the dog genome is more similar to that in humans than rodents

Haitina, Tatjana; Fredriksson, Robert; Foord, Steven M.; Schiöth, Helgi B. et al.

Part of BMC Genomics, p. 24, 2009

• DOI for The G protein-coupled receptor subset of the dog genome is more similar to that in humans than rodents

Hypothalamic FTO is associated with the regulation of energy intake not feeding reward

Olszewski, Pawel K; Fredriksson, Robert; Olszewska, Agnieszka M; Stephansson, Olga et al.

Part of BMC Neuroscience, p. 129, 2009

• DOI for Hypothalamic FTO is associated with the regulation of energy intake not feeding reward

Mapping the human membrane proteome: a majority of the human membrane proteins can be classified according to function and evolutionary origin

Almén, Markus Sällman; Nordström, Karl J V; Fredriksson, Robert; Schiöth, Helgi B

Part of BMC Biology, p. 50, 2009

• DOI for Mapping the human membrane proteome: a majority of the human membrane proteins can be classified according to function and evolutionary origin

Anxiolytic response after palatable diet consumption but not food restriction in rats

Alsiö, Johan; Pickering, Christopher; Roman, Erika; Lindblom, Jonas et al.

Part of Appetite, p. 816-816, 2009

The Secretin GPCRs descended from the family of Adhesion GPCRs

Nordström, Karl J V; Lagerström, Malin C; Wallér, Linn M J; Fredriksson, Robert et al.

Part of Molecular biology and evolution, p. 71-84, 2009

• DOI for The Secretin GPCRs descended from the family of Adhesion GPCRs

Withdrawal from free-choice high-fat high-sugar diet induces craving only in obesity-prone animals

Pickering, Chris; Alsiö, Johan; Hulting, Anna-Lena; Schiöth, Helgi B

Part of Psychopharmacology, p. 431-443, 2009

• DOI for Withdrawal from free-choice high-fat high-sugar diet induces craving only in obesity-prone animals

Motivation for sucrose in sated rats is predicted by low anxiety-like behavior

Alsiö, Johan; Pickering, Chris; Roman, Erika; Hulting, Anna-Lena et al.

Part of Neuroscience Letters, p. 193-197, 2009

• DOI for Motivation for sucrose in sated rats is predicted by low anxiety-like behavior

Inverse association of high-fat diet preference and anxiety-like behavior: a putative role for urocortin 2

Alsiö, Johan; Roman, Erika; Olszewski, Pawel K.; Jonsson, Petra et al.

Part of Genes, Brain and Behavior, p. 193-202, 2009

• DOI for Inverse association of high-fat diet preference and anxiety-like behavior: a putative role for urocortin 2

Sequence polymorphism in a marine bivalve (Perna canaliculus) orphan G protein-coupled receptor gene: preliminary description and possible implications

Fidler, Andrew E.; Schiöth, Helgi B.; Fredriksson, Robert

Part of New Zealand Journal of Marine and Freshwater Research, p. 953-964, 2009

Critical evaluation of the FANTOM3 non-coding RNA transcripts

Nordström, Karl J V; Mirza, Majd A I; Almén, Markus Sällman; Gloriam, David E et al.

Part of Genomics, p. 169-176, 2009

• DOI for Critical evaluation of the FANTOM3 non-coding RNA transcripts

Memory impairment induced by IL-1beta is reversed by alpha-MSH through central melanocortin-4 receptors

Gonzalez, Patricia Verónica; Schiöth, Helgi Birgir; Lasaga, Mercedes; Scimonelli, Teresa Nieves

Part of Brain, behavior, and immunity, p. 817-822, 2009

• DOI for Memory impairment induced by IL-1beta is reversed by alpha-MSH through central melanocortin-4 receptors

Impact of nandrolone decanoate on gene expression in endocrine systems related to the adverse effects of anabolic androgenic steroids

Alsiö, Johan; Birgner, Carolina; Björkblom, Lars; Isaksson, Pernilla et al.

Part of Basic & Clinical Pharmacology & Toxicology, p. 307-314, 2009

• DOI for Impact of nandrolone decanoate on gene expression in endocrine systems related to the adverse effects of anabolic androgenic steroids

Complexity of neural mechanisms underlying overconsumption of sugar in scheduled feeding: involvement of opioids, orexin, oxytocin and NPY

Olszewski, Pawel K; Shaw, Timothy J; Grace, Martha K; Höglund, Catherine E et al.

Part of Peptides, p. 226-233, 2009

• DOI for Complexity of neural mechanisms underlying overconsumption of sugar in scheduled feeding: involvement of opioids, orexin, oxytocin and NPY

Melanocortin peptides affect the motivation to feed in rainbow trout (Oncorhynchus mykiss)

Schjolden, Joachim; Schiöth, Helgi B.; Larhammar, Dan; Winberg, Svante et al.

Part of General and Comparative Endocrinology, p. 134-138, 2009

• DOI for Melanocortin peptides affect the motivation to feed in rainbow trout (Oncorhynchus mykiss)

Restricted cortical and amygdaloid removal of vesicular glutamate transporter 2 in preadolescent mice impacts dopaminergic activity and neuronal circuitry of higher brain function

Wallén-Mackenzie, Åsa; Nordenankar, Karin; Fejgin, Kim; Lagerström, Malin C et al.

Part of Journal of Neuroscience, p. 2238-2251, 2009

• DOI for Restricted cortical and amygdaloid removal of vesicular glutamate transporter 2 in preadolescent mice impacts dopaminergic activity and neuronal circuitry of higher brain function

Central ghrelin increases anxiety in the Open Field test and impairs retention memory in a passive avoidance task in neonatal chicks

Carvajal, Pedro; Carlini, Valeria P.; Schiöth, Helgi B.; de Barioglio, Susana R. et al.

Part of Neurobiology of Learning and Memory, p. 402-407, 2009

• DOI for Central ghrelin increases anxiety in the Open Field test and impairs retention memory in a passive avoidance task in neonatal chicks

The Adhesion GPCR GPR125 is specifically expressed in the choroid plexus and is upregulated following brain injury

Pickering, Chris; Hägglund, Maria; Szmydynger-Chodobska, Joanna; Marques, Fernanda et al.

Part of BMC Neuroscience, p. 97, 2008

• DOI for The Adhesion GPCR GPR125 is specifically expressed in the choroid plexus and is upregulated following brain injury

Expression profile of the entire family of Adhesion G protein-coupled receptors in mouse and rat

Haitina, Tatjana; Olsson, Fredrik; Stephansson, Olga; Alsiö, Johan et al.

Part of BMC Neuroscience, p. 43, 2008

• DOI for Expression profile of the entire family of Adhesion G protein-coupled receptors in mouse and rat

Extensive neuroadaptive changes in cortical gene-transcript expressions of the glutamate system in response to repeated intermittent MDMA administration in adolescent rats

Kindlundh-Högberg, Anna M S; Blomqvist, Anna; Malki, Rana; Schiöth, Helgi B

Part of BMC Neuroscience, p. 39, 2008

• DOI for Extensive neuroadaptive changes in cortical gene-transcript expressions of the glutamate system in response to repeated intermittent MDMA administration in adolescent rats

The amphioxus (Branchiostoma floridae) genome contains a highly diversified set of G protein-coupled receptors

Nordström, Karl J V; Fredriksson, Robert; Schiöth, Helgi B

Part of BMC Evolutionary Biology, p. 9, 2008

• DOI for The amphioxus (Branchiostoma floridae) genome contains a highly diversified set of G protein-coupled receptors

The solute carrier (SLC) complement of the human genome: phylogenetic classification reveals four major families

Fredriksson, Robert; Nordström, Karl J V; Stephansson, Olga; Hägglund, Maria G A et al.

Part of FEBS Letters, p. 3811-3816, 2008

• DOI for The solute carrier (SLC) complement of the human genome: phylogenetic classification reveals four major families

Novel genetic variant in FTO influences insulin levels and insulin resistance in severely obese children and adolescents.

Jacobsson, J. A.; Klovins, Janis; Kapa, I.; Danielsson, P et al.

Part of International Journal of Obesity, p. 1730-1735, 2008

• DOI for Novel genetic variant in FTO influences insulin levels and insulin resistance in severely obese children and adolescents.

The relative impact of chronic food restriction and acute food deprivation on plasma hormone levels and hypothalamic neuropeptide expression

Johansson, Andreas; Fredriksson, Robert; Winnergren, Sonja; Hulting, Anna-Lena et al.

Part of Peptides, p. 1588-1595, 2008

• DOI for The relative impact of chronic food restriction and acute food deprivation on plasma hormone levels and hypothalamic neuropeptide expression

Allelotyping by massively parallel pyrosequencing of SNP-carrying trinucleotide threads

Pettersson, Erik; Zajac, Pawel; Ståhl, Patrik L; Jacobsson, Josefin A et al.

Part of Human Mutation, p. 323-329, 2008

• DOI for Allelotyping by massively parallel pyrosequencing of SNP-carrying trinucleotide threads

Major gender difference in association of FTO gene variant among severely obese children with obesity and obesity related phenotypes.

Jacobsson, Josefin A.; Danielsson, Pernilla; Svensson, Victoria; Klovins, Janis et al.

Part of Biochemical and Biophysical Research Communications - BBRC, p. 476-482, 2008

• DOI for Major gender difference in association of FTO gene variant among severely obese children with obesity and obesity related phenotypes.

Reduced activity of monoamine oxidase in the rat brain following repeated nandrolone decanoate administration

Birgner, Carolina; Kindlundh-Högberg, Anna; Oreland, Lars; Alsiö, Johan et al.

Part of Brain Research, p. 103-110, 2008