Helgi Schiöth

The interplay of genetics and fatty acid metabolism: exploring their impact on metabolic syndrome in Swedish men

Oskarsdottir, Harpa; Palsson, Arnar; Olafsdottir, Erla B.; Giedraitis, Vilmantas et al.

Ingår i Nutrition Journal, 2025

• DOI för The interplay of genetics and fatty acid metabolism: exploring their impact on metabolic syndrome in Swedish men
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A global survey on the associations between the lockdown group, free memory recall and emotional responses during the COVID-19 lockdown

Oyejide, Aderemi O.; Besharati, Sahba N.; Alcock, Stephanie; Schiöth, Helgi et al.

Ingår i Scientific Reports, 2025

• DOI för A global survey on the associations between the lockdown group, free memory recall and emotional responses during the COVID-19 lockdown
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Carbonic anhydrase IX inhibition as a path to treat neuroblastoma

Petrosiute, Agne; Zaksauskas, Audrius; Luciunaite, Asta; Petrauskas, Vytautas et al.

Ingår i British Journal of Pharmacology, s. 1610-1629, 2025

• DOI för Carbonic anhydrase IX inhibition as a path to treat neuroblastoma

Synthesis, characterization, and computational evaluation of some synthesized xanthone derivatives: focus on kinase target network and biomedical properties

Muslim, Wisam Taher; Mohammad, Layth Jasim; Naji, Munaf M.; Karimi, Isaac et al.

Ingår i Frontiers in Pharmacology, 2025

• DOI för Synthesis, characterization, and computational evaluation of some synthesized xanthone derivatives: focus on kinase target network and biomedical properties
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Establishment and verification of a prognostic signature associated with fatty acid metabolism in endometrial cancer

Peng, Lu; Sun, Rui; Hao, Tingting; Mu, Yulong et al.

Ingår i Molecular Medicine Reports, 2025

• DOI för Establishment and verification of a prognostic signature associated with fatty acid metabolism in endometrial cancer
• Ladda ner fulltext (pdf) av Establishment and verification of a prognostic signature associated with fatty acid metabolism in endometrial cancer

The interplay of genetics and fatty acid metabolism: exploring their impact on metabolic syndrome in Swedish men

Oskarsdottir, Harpa; Palsson, Arnar; Olafsdottir, Erla B.; Giedraitis, Vilmantas et al.

Ingår i Nutrition Journal, 2025

• DOI för The interplay of genetics and fatty acid metabolism: exploring their impact on metabolic syndrome in Swedish men
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A global survey on the associations between the lockdown group, free memory recall and emotional responses during the COVID-19 lockdown

Oyejide, Aderemi O.; Besharati, Sahba N.; Alcock, Stephanie; Schiöth, Helgi et al.

Ingår i Scientific Reports, 2025

• DOI för A global survey on the associations between the lockdown group, free memory recall and emotional responses during the COVID-19 lockdown
• Ladda ner fulltext (pdf) av A global survey on the associations between the lockdown group, free memory recall and emotional responses during the COVID-19 lockdown

Carbonic anhydrase IX inhibition as a path to treat neuroblastoma

Petrosiute, Agne; Zaksauskas, Audrius; Luciunaite, Asta; Petrauskas, Vytautas et al.

Ingår i British Journal of Pharmacology, s. 1610-1629, 2025

• DOI för Carbonic anhydrase IX inhibition as a path to treat neuroblastoma

Synthesis, characterization, and computational evaluation of some synthesized xanthone derivatives: focus on kinase target network and biomedical properties

Muslim, Wisam Taher; Mohammad, Layth Jasim; Naji, Munaf M.; Karimi, Isaac et al.

Ingår i Frontiers in Pharmacology, 2025

• DOI för Synthesis, characterization, and computational evaluation of some synthesized xanthone derivatives: focus on kinase target network and biomedical properties
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Establishment and verification of a prognostic signature associated with fatty acid metabolism in endometrial cancer

Peng, Lu; Sun, Rui; Hao, Tingting; Mu, Yulong et al.

Ingår i Molecular Medicine Reports, 2025

• DOI för Establishment and verification of a prognostic signature associated with fatty acid metabolism in endometrial cancer
• Ladda ner fulltext (pdf) av Establishment and verification of a prognostic signature associated with fatty acid metabolism in endometrial cancer

Targeting platinum-resistant ovarian cancer by disrupting histone and RAD51 lactylation

Sun, Chenggong; Li, Xiao; Teng, Qiuli; Liu, Xihan et al.

Ingår i Theranostics, s. 3055-3075, 2025

• DOI för Targeting platinum-resistant ovarian cancer by disrupting histone and RAD51 lactylation

New label-free serum exosomes detection method based on hierarchical SERS substrate for diagnosis of pancreatic cancer using AI

Wang, Hu; Li, Yanru; Chen, Shuai; Yan, Jie et al.

Ingår i Sensors and actuators. B, Chemical, 2025

• DOI för New label-free serum exosomes detection method based on hierarchical SERS substrate for diagnosis of pancreatic cancer using AI
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Ketamine and Esketamine in Clinical Trials: FDA‐Approved and Emerging Indications, Trial Trends With Putative Mechanistic Explanations

Vekhova, Ksenia A.; Namiot, Eugenia D.; Jonsson, Jörgen; Schiöth, Helgi

Ingår i Clinical Pharmacology and Therapeutics, s. 374-386, 2025

• DOI för Ketamine and Esketamine in Clinical Trials: FDA‐Approved and Emerging Indications, Trial Trends With Putative Mechanistic Explanations
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GPCR drug discovery: new agents, targets and indications

Lorente, Javier Sánchez; Sokolov, Aleksandr V.; Ferguson, Gavin; Schiöth, Helgi et al.

Ingår i Nature reviews. Drug discovery, 2025

• DOI för GPCR drug discovery: new agents, targets and indications

Migraine and its major subtypes: with and without aura are associated with polygenic scores for autism

Mohammad, Salahuddin; Bussu, Giorgia; Rukh, Gull; Schiöth, Helgi B. et al.

Ingår i Cephalalgia, s. 1-12, 2025

• DOI för Migraine and its major subtypes: with and without aura are associated with polygenic scores for autism
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Associations between genetic variations in oxytocin pathway genes and hippocampal volume: Insights from the UK Biobank

Xiao, Shanshan; Ebner, Natalie C.; Dang, Junhua; Rukh, Gull et al.

Ingår i Cortex, s. 211-219, 2025

• DOI för Associations between genetic variations in oxytocin pathway genes and hippocampal volume: Insights from the UK Biobank
• Ladda ner fulltext (pdf) av Associations between genetic variations in oxytocin pathway genes and hippocampal volume: Insights from the UK Biobank

Targeted anticancer pre-vinylsulfone covalent inhibitors of carbonic anhydrase IX

Vaškevičius, Aivaras; Baronas, Denis; Leitans, Janis; Kvietkauskaitė, Agnė et al.

Ingår i eLIFE, 2024

• DOI för Targeted anticancer pre-vinylsulfone covalent inhibitors of carbonic anhydrase IX
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Pre-prandial plasma liver-expressed antimicrobial peptide 2 (LEAP2) concentration in humans is inversely associated with hunger sensation in a ghrelin independent manner

Andreoli, María Florencia; Fittipaldi, Antonela S; Castrogiovanni, Daniel; De Francesco, Pablo N et al.

Ingår i European Journal of Nutrition, s. 751-762, 2024

• DOI för Pre-prandial plasma liver-expressed antimicrobial peptide 2 (LEAP2) concentration in humans is inversely associated with hunger sensation in a ghrelin independent manner

Differential change in alcohol consumption during the COVID-19 pandemic: the role of loneliness, socialization, and mental well-being

Mohamed, Mohamed S.; Rukh, Gull; Vadlin, Sofia; Olofsdotter, Susanne et al.

Ingår i Frontiers in Psychiatry, 2024

• DOI för Differential change in alcohol consumption during the COVID-19 pandemic: the role of loneliness, socialization, and mental well-being
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Differentiating the relationships between traditional and new media use and sleep quality during the COVID-19 pandemic: roles of psychological distress and age

Xu, Tong; Zhu, Dongmei; Yu, Zhaoliang; Dang, Junhua et al.

Ingår i Frontiers in Psychology, 2024

• DOI för Differentiating the relationships between traditional and new media use and sleep quality during the COVID-19 pandemic: roles of psychological distress and age
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Social support predicted subsequent subjective well-being during the COVID-19 pandemic: a prospective study

Mao, Yanhui; Chen, Junpeng; Liu, Xinqi; Dang, Junhua et al.

Ingår i BMC Public Health, 2024

• DOI för Social support predicted subsequent subjective well-being during the COVID-19 pandemic: a prospective study
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Long-term changes in adiposity markers during and after antidepressant therapy in a community cohort

Mwinyi, Jessica; Strippoli, Marie-Pierre F.; Kanders, Sofia H.; Schiöth, Helgi et al.

Ingår i Translational Psychiatry, 2024

• DOI för Long-term changes in adiposity markers during and after antidepressant therapy in a community cohort
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LEAP2 is associated with impulsivity and reward sensitivity depending on the nutritional status and decreases with protein intake in humans

Andreoli, María Florencia; Kruger, Ana Luz; Sokolov, Aleksandr V.; Rukh, Gull et al.

Ingår i Diabetes, obesity and metabolism, s. 4734-4743, 2024

• DOI för LEAP2 is associated with impulsivity and reward sensitivity depending on the nutritional status and decreases with protein intake in humans
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Hidden liver-joint axis: HBV infection causes rheumatoid arthritis via TRAFD1 with imbalance of HBV X protein and trans-ferulic acid

Zhao, Na; Zhang, Xiaoyu; Wang, Xilong; Liu, Zhipu et al.

Ingår i Virulence, 2024

• DOI för Hidden liver-joint axis: HBV infection causes rheumatoid arthritis via TRAFD1 with imbalance of HBV X protein and trans-ferulic acid
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The Concentration of Liver-Expressed Antimicrobial Peptide 2 in Human Milk and Infant Plasma Is Positively Associated with Adiposity and Body Weight in the First Year of Life

Kruger, Ana Luz; Malpeli, Agustina; Sala, Marisa; Casado, Carla et al.

Ingår i Journal of Nutrition, s. 3388-3399, 2024

• DOI för The Concentration of Liver-Expressed Antimicrobial Peptide 2 in Human Milk and Infant Plasma Is Positively Associated with Adiposity and Body Weight in the First Year of Life

Genomic Validation in the UK Biobank Cohort Suggests a Role of C8B and MFG-E8 in the Pathogenesis of Trigeminal Neuralgia

Lafta, Muataz S.; Rukh, Gull; Abu Hamdeh, Sami; Molero, Yasmina et al.

Ingår i Journal of Molecular Neuroscience, 2024

• DOI för Genomic Validation in the UK Biobank Cohort Suggests a Role of C8B and MFG-E8 in the Pathogenesis of Trigeminal Neuralgia
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Genetic variants of LEAP2 are associated with anthropometric traits and circulating insulin-like growth factor-1 concentration: A UK Biobank study

Andreoli, María Florencia; Gentreau, Mélissa; Rukh, Gull; Perelló, Mario et al.

Ingår i Diabetes, obesity and metabolism, s. 3565-3575, 2024

• DOI för Genetic variants of LEAP2 are associated with anthropometric traits and circulating insulin-like growth factor-1 concentration: A UK Biobank study
• Ladda ner fulltext (pdf) av Genetic variants of LEAP2 are associated with anthropometric traits and circulating insulin-like growth factor-1 concentration: A UK Biobank study

Oxytocin pathway gene variation and corticostriatal resting-state functional connectivity

Xiao, Shanshan; Fischer, Håkan; Ebner, Natalie C.; Rukh, Gull et al.

Ingår i COMPREHENSIVE PSYCHONEUROENDOCRINOLOGY, 2024

• DOI för Oxytocin pathway gene variation and corticostriatal resting-state functional connectivity
• Ladda ner fulltext (pdf) av Oxytocin pathway gene variation and corticostriatal resting-state functional connectivity

A deep learning model for brain age prediction using minimally preprocessed T1w images as input

Dartora, Caroline; Marseglia, Anna; Martensson, Gustav; Rukh, Gull et al.

Ingår i Frontiers in Aging Neuroscience, 2024

• DOI för A deep learning model for brain age prediction using minimally preprocessed T1w images as input
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Hydroxymethylglutaryl-CoA reductase activity is essential for mitochondrial β-oxidation of fatty acids to prevent lethal accumulation of long-chain acylcarnitines in the mouse liver

Liepinsh, Edgars; Zvejniece, Liga; Clemensson, Laura; Ozola, Melita et al.

Ingår i British Journal of Pharmacology, s. 2750-2773, 2024

• DOI för Hydroxymethylglutaryl-CoA reductase activity is essential for mitochondrial β-oxidation of fatty acids to prevent lethal accumulation of long-chain acylcarnitines in the mouse liver
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Off-target effects of statins: molecular mechanisms, side effects and the emerging role of kinases

Lagunas-Rangel, Francisco Alejandro; Liepinsh, Edgars; Fredriksson, Robert; Alsehli, Ahmed M. et al.

Ingår i British Journal of Pharmacology, s. 3799-3818, 2024

• DOI för Off-target effects of statins: molecular mechanisms, side effects and the emerging role of kinases
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Exploring biomarkers in trigeminal neuralgia patients operated with microvascular decompression: A comparison with multiple sclerosis patients and non-neurological controls

Lafta, Muataz S; Sokolov, Aleksandr V.; Landtblom, Anne-Marie; Ericson, Hans et al.

Ingår i European Journal of Pain, s. 929-942, 2024

• DOI för Exploring biomarkers in trigeminal neuralgia patients operated with microvascular decompression: A comparison with multiple sclerosis patients and non-neurological controls
• Ladda ner fulltext (pdf) av Exploring biomarkers in trigeminal neuralgia patients operated with microvascular decompression: A comparison with multiple sclerosis patients and non-neurological controls

Depression proteomic profiling in adolescents with transcriptome analyses in independent cohorts

Sokolov, Aleksandr V.; Lafta, Muataz; Nordberg, Didi; Jonsson, Jörgen et al.

Ingår i Frontiers in Psychiatry, 2024

• DOI för Depression proteomic profiling in adolescents with transcriptome analyses in independent cohorts
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Selective Colocalization of GHSR and GLP-1R in a Subset of Hypothalamic Neurons and Their Functional Interaction

Aguggia, Julieta; Fernandez, Gimena; Cassano, Daniela; Mustafá, Emilio R. et al.

Ingår i Endocrinology, 2024

• DOI för Selective Colocalization of GHSR and GLP-1R in a Subset of Hypothalamic Neurons and Their Functional Interaction

Increased ROS levels, antioxidant defense disturbances and bioenergetic disruption induced by thiosulfate administration in the brain of neonatal rats

Manzke Glänzel, Nícolas; Teixeira da Rosa-Junior, Nevton; Signori, Marian F.; de Andrade Silveira, Josyane et al.

Ingår i Metabolic brain disease, 2024

• DOI för Increased ROS levels, antioxidant defense disturbances and bioenergetic disruption induced by thiosulfate administration in the brain of neonatal rats

Statin use is associated with higher white matter hyperintensity volumes and lower grey matter volumes

Gentreau, Mélissa; Miguet, Maud; Affatato, Oreste; Rukh, Gull et al.

Ingår i Brain Communications, 2024

• DOI för Statin use is associated with higher white matter hyperintensity volumes and lower grey matter volumes
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Perfluorooctanoic acid induces transgenerational modifications in reproduction, metabolism, locomotor activity, and sleep behavior in Drosophila melanogaster and deleterious effects in human cancer cells.

Liao, Sifang; Sun, Chengxi; Lagunas-Rangel, Francisco Alejandro; Liu, Wen et al.

Ingår i Science of the Total Environment, s. 177472, 2024

• DOI för Perfluorooctanoic acid induces transgenerational modifications in reproduction, metabolism, locomotor activity, and sleep behavior in Drosophila melanogaster and deleterious effects in human cancer cells.

Advances in development of biomarkers for brain damage and ischemia

Karimova, Diana; Rostami, Elham; Chubarev, Vladimir N.; Tarasov, Vadim V. et al.

Ingår i Molecular Biology Reports, 2024

• DOI för Advances in development of biomarkers for brain damage and ischemia
• Ladda ner fulltext (pdf) av Advances in development of biomarkers for brain damage and ischemia

Decoding depression: a comprehensive multi-cohort exploration of blood DNA methylation using machine learning and deep learning approaches

Sokolov, Aleksandr V.; Schiöth, Helgi

Ingår i Translational Psychiatry, 2024

• DOI för Decoding depression: a comprehensive multi-cohort exploration of blood DNA methylation using machine learning and deep learning approaches
• Ladda ner fulltext (pdf) av Decoding depression: a comprehensive multi-cohort exploration of blood DNA methylation using machine learning and deep learning approaches

Conceptual foundations of acetylcarnitine supplementation in neuropsychiatric long COVID syndrome: a narrative review.

Helbing, Dario Lucas; Dommaschk, Eva-Maria; Danyeli, Lena Vera; Liepinsh, Edgars et al.

Ingår i European Archives of Psychiatry and Clinical Neuroscience, 2024

• DOI för Conceptual foundations of acetylcarnitine supplementation in neuropsychiatric long COVID syndrome: a narrative review.

The exposure to UV filters: Prevalence, effects, possible molecular mechanisms of action and interactions within mixtures

Rafeletou, Alexandra; Niemi, Jenni; Lagunas-Rangel, Francisco Alejandro; Liu, Wen et al.

Ingår i Science of the Total Environment, 2024

• DOI för The exposure to UV filters: Prevalence, effects, possible molecular mechanisms of action and interactions within mixtures

Recent developments of topoisomerase inhibitors: Clinical trials, emerging indications, novel molecules and global sales

Bondarev, Andrey D.; Jonsson, Jörgen; Chubarev, Vladimir N.; V. Tarasov, Vadim et al.

Ingår i Pharmacological Research, 2024

• DOI för Recent developments of topoisomerase inhibitors: Clinical trials, emerging indications, novel molecules and global sales
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Blockade of the lncRNA-PART1-PHB2 axis confers resistance to PARP inhibitor and promotes cellular senescence in ovarian cancer

Wu, Huan; Sun, Chenggong; Cao, Wenyu; Teng, Qiuli et al.

Ingår i Cancer Letters, 2024

• DOI för Blockade of the lncRNA-PART1-PHB2 axis confers resistance to PARP inhibitor and promotes cellular senescence in ovarian cancer
• Ladda ner fulltext (pdf) av Blockade of the lncRNA-PART1-PHB2 axis confers resistance to PARP inhibitor and promotes cellular senescence in ovarian cancer

Association of polygenic scores for autism with volumetric MRI phenotypes in cerebellum and brainstem in adults

Mohammad, Salahuddin; Gentreau, Mélissa; Dubol, Manon; Rukh, Gull et al.

Ingår i Molecular Autism, 2024

• DOI för Association of polygenic scores for autism with volumetric MRI phenotypes in cerebellum and brainstem in adults
• Ladda ner fulltext (pdf) av Association of polygenic scores for autism with volumetric MRI phenotypes in cerebellum and brainstem in adults

Identifying proteomic risk factors for overall, aggressive, and early onset prostate cancer using Mendelian Randomisation and tumour spatial transcriptomics

Desai, Trishna A.; Hedman, Asa K.; Dimitriou, Marios; Koprulu, Mine et al.

Ingår i EBioMedicine, 2024

• DOI för Identifying proteomic risk factors for overall, aggressive, and early onset prostate cancer using Mendelian Randomisation and tumour spatial transcriptomics
• Ladda ner fulltext (pdf) av Identifying proteomic risk factors for overall, aggressive, and early onset prostate cancer using Mendelian Randomisation and tumour spatial transcriptomics

Identifying therapeutic targets for cancer among 2074 circulating proteins and risk of nine cancers

Smith-Byrne, Karl; Hedman, Åsa; Dimitriou, Marios; Desai, Trishna et al.

Ingår i Nature Communications, 2024

• DOI för Identifying therapeutic targets for cancer among 2074 circulating proteins and risk of nine cancers
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Response to the Comment on "The Effects of Statins on Cognitive Performance Are Mediated by Low-Density Lipoprotein, C-Reactive Protein, and Blood Glucose Concentrations"

Gentreau, Melissa; Rukh, Gull; Miguet, Maud; Clemensson, Laura et al.

Ingår i The journals of gerontology. Series A, Biological sciences and medical sciences, 2024

• DOI för Response to the Comment on "The Effects of Statins on Cognitive Performance Are Mediated by Low-Density Lipoprotein, C-Reactive Protein, and Blood Glucose Concentrations"

STING inhibitors sensitize platinum chemotherapy in ovarian cancer by inhibiting the CGAS-STING pathway in cancer-associated fibroblasts (CAFs)

Liu, Jiale; Liu, Chenmian; Ma, Yana; Pan, Xiyu et al.

Ingår i Cancer Letters, 2024

• DOI för STING inhibitors sensitize platinum chemotherapy in ovarian cancer by inhibiting the CGAS-STING pathway in cancer-associated fibroblasts (CAFs)
• Ladda ner fulltext (pdf) av STING inhibitors sensitize platinum chemotherapy in ovarian cancer by inhibiting the CGAS-STING pathway in cancer-associated fibroblasts (CAFs)

Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes

Al-Sabri, Mohamed H.; Ammar, Nourhane; Korzh, Stanislava; Alsehli, Ahmed M. et al.

Ingår i Scientific Reports, 2024

• DOI för Fluvastatin-induced myofibrillar damage is associated with elevated ROS, and impaired fatty acid oxidation, and is preceded by mitochondrial morphological changes
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Synthesis of a Rivastigmine and Insulin Combinational Mucoadhesive Nanoparticle for Intranasal Delivery

Jamshidnejad-Tosaramandani, Tahereh; Kashanian, Soheila; Karimi, Isaac; Schiöth, Helgi

Ingår i Polymers, 2024

• DOI för Synthesis of a Rivastigmine and Insulin Combinational Mucoadhesive Nanoparticle for Intranasal Delivery
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PLBD: protein-ligand binding database of thermodynamic and kinetic intrinsic parameters

Linge, Darius; Gedgaudas, Marius; Merkys, Andrius; Petrauskas, Vytautas et al.

Ingår i Database, 2023

• DOI för PLBD: protein-ligand binding database of thermodynamic and kinetic intrinsic parameters
• Ladda ner fulltext (pdf) av PLBD: protein-ligand binding database of thermodynamic and kinetic intrinsic parameters

Perceived stress is related to lower blood pressure in a Swedish cohort

Miguet, Maud; Olivo, Gaia; Ciuculete, Diana-Maria; Elmståhl, Sölve et al.

Ingår i Scandinavian Journal of Public Health, s. 611-618, 2023

• DOI för Perceived stress is related to lower blood pressure in a Swedish cohort
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Job satisfaction and job tenure of people with mental health disorders: a UK Biobank cohort study

Mohammad, Salahuddin; Miguet, Maud; Rukh, Gull; Schiöth, Helgi B. et al.

Ingår i Scandinavian Journal of Public Health, s. 1248-1257, 2023

• DOI för Job satisfaction and job tenure of people with mental health disorders: a UK Biobank cohort study
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Worsened Anxiety and Loneliness Influenced Gaming and Gambling during the COVID-19 Pandemic

Mohamed, Mohamed S.; Rukh, Gull; Schiöth, Helgi B.; Vadlin, Sofia et al.

Ingår i Journal of Clinical Medicine, 2023

• DOI för Worsened Anxiety and Loneliness Influenced Gaming and Gambling during the COVID-19 Pandemic
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Methylation in MAD1L1 is associated with the severity of suicide attempt and phenotypes of depression

Sokolov, Aleksandr V.; Manu, Diana-Maria; Nordberg, Didi O. T.; Boström, Adrian D. E. et al.

Ingår i Clinical Epigenetics, 2023

• DOI för Methylation in MAD1L1 is associated with the severity of suicide attempt and phenotypes of depression
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Ghrelin's orexigenic action in the lateral hypothalamic area involves indirect recruitment of orexin neurons and arcuate nucleus activation

Barrile, Franco; Cassano, Daniela; Fernandez, Gimena; De Francesco, Pablo N. et al.

Ingår i Psychoneuroendocrinology, 2023

• DOI för Ghrelin's orexigenic action in the lateral hypothalamic area involves indirect recruitment of orexin neurons and arcuate nucleus activation

The international clinical trials registry platform (ICTRP): data integrity and the trends in clinical trials, diseases, and drugs

Namiot, Eugenia D.; Smirnovová, Diana; Sokolov, Aleksandr V.; Chubarev, Vladimir N. et al.

Ingår i Frontiers in Pharmacology, 2023

• DOI för The international clinical trials registry platform (ICTRP): data integrity and the trends in clinical trials, diseases, and drugs
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Assessing volumetric brain differences in migraine and depression patients: a UK Biobank study

Affatato, Oreste; Dahlén, Amelia; Rukh, Gull; Schiöth, Helgi B. et al.

Ingår i BMC Neurology, 2023

• DOI för Assessing volumetric brain differences in migraine and depression patients: a UK Biobank study
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Synthesis of an insulin-loaded mucoadhesive nanoparticle designed for intranasal administration: focus on new diffusion media

Jamshidnejad-Tosaramandani, Tahereh; Kashanian, Soheila; Karimi, Isaac; Schiöth, Helgi B.

Ingår i Frontiers in Pharmacology, 2023

• DOI för Synthesis of an insulin-loaded mucoadhesive nanoparticle designed for intranasal administration: focus on new diffusion media
• Ladda ner fulltext (pdf) av Synthesis of an insulin-loaded mucoadhesive nanoparticle designed for intranasal administration: focus on new diffusion media

The Effects of Statins on Cognitive Performance Are Mediated by Low-Density Lipoprotein, C-Reactive Protein, and Blood Glucose Concentrations

Gentreau, Mélissa; Rukh, Gull; Miguet, Maud; Clemensson, Laura et al.

Ingår i The journals of gerontology. Series A, Biological sciences and medical sciences, s. 1964-1972, 2023

• DOI för The Effects of Statins on Cognitive Performance Are Mediated by Low-Density Lipoprotein, C-Reactive Protein, and Blood Glucose Concentrations
• Ladda ner fulltext (pdf) av The Effects of Statins on Cognitive Performance Are Mediated by Low-Density Lipoprotein, C-Reactive Protein, and Blood Glucose Concentrations

Well-being spectrum traits are associated with polygenic scores for autism

Mohammad, Salahuddin; de Ruijter, Markus J. T.; Rukh, Gull; Rask-Andersen, Mathias et al.

Ingår i Autism Research, s. 1891-1902, 2023

• DOI för Well-being spectrum traits are associated with polygenic scores for autism
• Ladda ner fulltext (pdf) av Well-being spectrum traits are associated with polygenic scores for autism

Volumetric Differences in Cerebellum and Brainstem in Patients with Migraine: A UK Biobank Study

Affatato, Oreste; Rukh, Gull; Schiöth, Helgi B.; Mwinyi, Jessica

Ingår i Biomedicines, 2023

• DOI för Volumetric Differences in Cerebellum and Brainstem in Patients with Migraine: A UK Biobank Study
• Ladda ner fulltext (pdf) av Volumetric Differences in Cerebellum and Brainstem in Patients with Migraine: A UK Biobank Study

Migraine, inflammatory bowel disease and celiac disease: A Mendelian randomization study

Welander, Nike Zoe; Rukh, Gull; Rask-Andersen, Mathias; Harder, Aster V E et al.

Ingår i Headache, s. 642-651, 2023

• DOI för Migraine, inflammatory bowel disease and celiac disease: A Mendelian randomization study
• Ladda ner fulltext (pdf) av Migraine, inflammatory bowel disease and celiac disease: A Mendelian randomization study

Artificial Neural Network (ANN)-Based Pattern Recognition Approach Illustrates a Biphasic Behavioral Effect of Ethanol in Zebrafish: A High-Throughput Method for Animal Locomotor Analysis

Myrov, Vladislav O; Polovian, Aleksandr I.; Kolchanova, Sofiia; Galumov, Georgii K et al.

Ingår i Biomedicines, 2023

• DOI för Artificial Neural Network (ANN)-Based Pattern Recognition Approach Illustrates a Biphasic Behavioral Effect of Ethanol in Zebrafish: A High-Throughput Method for Animal Locomotor Analysis
• Ladda ner fulltext (pdf) av Artificial Neural Network (ANN)-Based Pattern Recognition Approach Illustrates a Biphasic Behavioral Effect of Ethanol in Zebrafish: A High-Throughput Method for Animal Locomotor Analysis

Efficacy of combination therapy with GABA, a DPP-4i and a PPI as an adjunct to insulin therapy in patients with type 1 diabetes

Rabinovitch, Alexander; Koshelev, Daniil; Lagunas-Rangel, Francisco Alejandro; Kosheleva, Liudmila et al.

Ingår i Frontiers in Endocrinology, 2023

• DOI för Efficacy of combination therapy with GABA, a DPP-4i and a PPI as an adjunct to insulin therapy in patients with type 1 diabetes
• Ladda ner fulltext (pdf) av Efficacy of combination therapy with GABA, a DPP-4i and a PPI as an adjunct to insulin therapy in patients with type 1 diabetes

Evidence for Prepulse Inhibition of Visually Evoked Motor Response in Drosophila melanogaster

Schiöth, Helgi B.; Donzelli, Laura; Arvidsson, Nicklas; Williams, Michael J. et al.

Ingår i Biology, 2023

• DOI för Evidence for Prepulse Inhibition of Visually Evoked Motor Response in Drosophila melanogaster
• Ladda ner fulltext (pdf) av Evidence for Prepulse Inhibition of Visually Evoked Motor Response in Drosophila melanogaster

Epigenetic changes in the CYP2D6 gene are related to severity of suicide attempt: A cross-sectional study of suicide attempters

Bostrom, Adrian E. Desai; Jamshidi, Esmail; Manu, Diana-Maria; Kular, Lara et al.

Ingår i Journal of Psychiatric Research, s. 217-224, 2023

• DOI för Epigenetic changes in the CYP2D6 gene are related to severity of suicide attempt: A cross-sectional study of suicide attempters
• Ladda ner fulltext (pdf) av Epigenetic changes in the CYP2D6 gene are related to severity of suicide attempt: A cross-sectional study of suicide attempters

Drosophila as a Rapid Screening Model to Evaluate the Hypoglycemic Effects of Dipeptidyl Peptidase 4 (DPP4) Inhibitors: High Evolutionary Conservation of DPP4

Lagunas-Rangel, Francisco Alejandro; Liao, Sifang; Williams, Michael J.; Trukhan, Vladimir et al.

Ingår i Biomedicines, 2023

• DOI för Drosophila as a Rapid Screening Model to Evaluate the Hypoglycemic Effects of Dipeptidyl Peptidase 4 (DPP4) Inhibitors: High Evolutionary Conservation of DPP4
• Ladda ner fulltext (pdf) av Drosophila as a Rapid Screening Model to Evaluate the Hypoglycemic Effects of Dipeptidyl Peptidase 4 (DPP4) Inhibitors: High Evolutionary Conservation of DPP4

Evaluation of circulating plasma proteins in breast cancer using Mendelian randomisation

Mälarstig, Anders; Grassmann, Felix; Dahl, Leo; Dimitriou, Marios et al.

Ingår i Nature Communications, 2023

• DOI för Evaluation of circulating plasma proteins in breast cancer using Mendelian randomisation
• Ladda ner fulltext (pdf) av Evaluation of circulating plasma proteins in breast cancer using Mendelian randomisation

Higher fresh fruit intake relates to larger grey matter volumes in areas involved in dementia and depression: A UK Biobank study

Gaudio, Santino; Rukh, Gull; Di Ciommo, Vincenzo; Berkins, Samuel et al.

Ingår i NeuroImage, 2023

• DOI för Higher fresh fruit intake relates to larger grey matter volumes in areas involved in dementia and depression: A UK Biobank study
• Ladda ner fulltext (pdf) av Higher fresh fruit intake relates to larger grey matter volumes in areas involved in dementia and depression: A UK Biobank study

Fusobacterium nucleatum- induced exosomal HOTTIP promotes gastric cancer progression through the microRNA-885-3p/EphB2 axis

Xin, Yiwei; Li, Xinyang; Zhang, Mengjiao; Shang, Ziqi et al.

Ingår i Cancer Science, s. 2360-2374, 2023

• DOI för Fusobacterium nucleatum- induced exosomal HOTTIP promotes gastric cancer progression through the microRNA-885-3p/EphB2 axis
• Ladda ner fulltext (pdf) av Fusobacterium nucleatum- induced exosomal HOTTIP promotes gastric cancer progression through the microRNA-885-3p/EphB2 axis

Knockout of Tmlhe in mice is not associated with autism spectrum disorder phenotypes or motor dysfunction despite low carnitine levels

Liepinsh, Edgars; Svalbe, Baiba; Stelfa, Gundega; Grinberga, Solveiga et al.

Ingår i Molecular Autism, 2023

• DOI för Knockout of Tmlhe in mice is not associated with autism spectrum disorder phenotypes or motor dysfunction despite low carnitine levels
• Ladda ner fulltext (pdf) av Knockout of Tmlhe in mice is not associated with autism spectrum disorder phenotypes or motor dysfunction despite low carnitine levels

Interaction between environmental pollutants and cancer drug efficacy: Bisphenol A, Bisphenol A diglycidyl ether and Perfluorooctanoic acid reduce vincristine cytotoxicity in acute lymphoblastic leukemia cells

Lagunas-Rangel, Francisco Alejandro; Liu, Wen; Schiöth, Helgi B.

Ingår i Journal of Applied Toxicology, s. 458-469, 2023

• DOI för Interaction between environmental pollutants and cancer drug efficacy: Bisphenol A, Bisphenol A diglycidyl ether and Perfluorooctanoic acid reduce vincristine cytotoxicity in acute lymphoblastic leukemia cells
• Ladda ner fulltext (pdf) av Interaction between environmental pollutants and cancer drug efficacy: Bisphenol A, Bisphenol A diglycidyl ether and Perfluorooctanoic acid reduce vincristine cytotoxicity in acute lymphoblastic leukemia cells

Effect of worry, depression, and sensitivity to environmental stress owing to neurotic personality on risk of cardiovascular disease: A Mendelian randomization study

Rukh, Gull; de Ruijter, Markus; Schiöth, Helgi Birgir

Ingår i Journal of personality, s. 856-867, 2023

• DOI för Effect of worry, depression, and sensitivity to environmental stress owing to neurotic personality on risk of cardiovascular disease: A Mendelian randomization study
• Ladda ner fulltext (pdf) av Effect of worry, depression, and sensitivity to environmental stress owing to neurotic personality on risk of cardiovascular disease: A Mendelian randomization study

Job satisfaction has differential associations with delay discounting and risk-taking

de Ruijter, Markus J. T.; Dahlén, Amelia; Rukh, Gull; Schiöth, Helgi B.

Ingår i Scientific Reports, 2023

• DOI för Job satisfaction has differential associations with delay discounting and risk-taking
• Ladda ner fulltext (pdf) av Job satisfaction has differential associations with delay discounting and risk-taking

Identification and validation of volatile organic compounds in bile for differential diagnosis of perihilar cholangiocarcinoma

Gui, Xinru; Zhang, Xin; Xin, Yiwei; Liu, Qi et al.

Ingår i Clinica Chimica Acta, 2023

• DOI för Identification and validation of volatile organic compounds in bile for differential diagnosis of perihilar cholangiocarcinoma
• Ladda ner fulltext (pdf) av Identification and validation of volatile organic compounds in bile for differential diagnosis of perihilar cholangiocarcinoma

Role of the hypothalamus in ghrelin effects on reproduction: sperm function and sexual behavior in male mice

Poretti, María Belén; Bianconi, Santiago; Luque, Eugenia; Martini, Ana Carolina et al.

Ingår i Reproduction, s. 123-134, 2023

• DOI för Role of the hypothalamus in ghrelin effects on reproduction: sperm function and sexual behavior in male mice

Effects of Transient Administration of the NMDA Receptor Antagonist MK-801 in Drosophila melanogaster Activity, Sleep, and Negative Geotaxis

Moulin, Thiago; Stojanovic, Tijana; Rajesh, Rasika P.; Pareek, Tirusha et al.

Ingår i Biomedicines, 2023

• DOI för Effects of Transient Administration of the NMDA Receptor Antagonist MK-801 in Drosophila melanogaster Activity, Sleep, and Negative Geotaxis
• Ladda ner fulltext (pdf) av Effects of Transient Administration of the NMDA Receptor Antagonist MK-801 in Drosophila melanogaster Activity, Sleep, and Negative Geotaxis

How Sleep-Deprived People See and Evaluate Others' Faces: An Experimental Study

van Egmond, Lieve; Meth, Elisa; Bukhari, Shervin; Engström, Joachim et al.

Ingår i Nature and Science of Sleep, s. 867-876, 2022

• DOI för How Sleep-Deprived People See and Evaluate Others' Faces: An Experimental Study
• Ladda ner fulltext (pdf) av How Sleep-Deprived People See and Evaluate Others' Faces: An Experimental Study

Generation of Endogenous Promoter-Driven Luciferase Reporter System Using CRISPR/Cas9 for Investigating Transcriptional Regulation of the Core Clock Gene BMAL1

Sun, Chengxi; Li, Su-Chen; Liu, Wen; Schiöth, Helgi B.

Ingår i Biomedicines, 2022

• DOI för Generation of Endogenous Promoter-Driven Luciferase Reporter System Using CRISPR/Cas9 for Investigating Transcriptional Regulation of the Core Clock Gene BMAL1
• Ladda ner fulltext (pdf) av Generation of Endogenous Promoter-Driven Luciferase Reporter System Using CRISPR/Cas9 for Investigating Transcriptional Regulation of the Core Clock Gene BMAL1

HMDB 5.0: the Human Metabolome Database for 2022

Wishart, David S.; Guo, AnChi; Oler, Eponine; Wang, Fei et al.

Ingår i Nucleic Acids Research, 2022

• DOI för HMDB 5.0: the Human Metabolome Database for 2022
• Ladda ner fulltext (pdf) av HMDB 5.0: the Human Metabolome Database for 2022

Self-Reported Psychosomatic Complaints and Conduct Problems in Swedish Adolescents

Brooks, Samantha J.; Titova, Olga E; Ashworth, Emma L.; Bylund, Simon B. A. et al.

Ingår i Children, 2022

• DOI för Self-Reported Psychosomatic Complaints and Conduct Problems in Swedish Adolescents
• Ladda ner fulltext (pdf) av Self-Reported Psychosomatic Complaints and Conduct Problems in Swedish Adolescents

The Statin Target HMG-Coenzyme a Reductase (Hmgcr) Regulates Sleep Homeostasis in Drosophila

Alsehli, Ahmed M.; Liao, Sifang; Al-Sabri, Mohamed H.; Vasionis, Lukas et al.

Ingår i Pharmaceuticals, 2022

• DOI för The Statin Target HMG-Coenzyme a Reductase (Hmgcr) Regulates Sleep Homeostasis in Drosophila
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The influence of personality on the risk of myocardial infarction in UK Biobank cohort

Dahlén, Amelia; Miguet, Maud; Schiöth, Helgi B.; Rukh, Gull

Ingår i Scientific Reports, 2022

• DOI för The influence of personality on the risk of myocardial infarction in UK Biobank cohort
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Design, Synthesis and Biological Evaluation of Neogliptin, a Novel 2-Azabicyclo[2.2.1]heptane-Based Inhibitor of Dipeptidyl Peptidase-4 (DPP-4)

Maslov, Ivan O.; Zinevich, Tatiana; Kirichenko, Olga G.; Trukhan, Mikhail et al.

Ingår i Pharmaceuticals, 2022

• DOI för Design, Synthesis and Biological Evaluation of Neogliptin, a Novel 2-Azabicyclo[2.2.1]heptane-Based Inhibitor of Dipeptidyl Peptidase-4 (DPP-4)
• Ladda ner fulltext (pdf) av Design, Synthesis and Biological Evaluation of Neogliptin, a Novel 2-Azabicyclo[2.2.1]heptane-Based Inhibitor of Dipeptidyl Peptidase-4 (DPP-4)

Enhanced Toxicity of Bisphenols Together with UV Filters in Water: Identification of Synergy and Antagonism in Three-Component Mixtures

Kudlak, Blazej; Jatkowska, Natalia; Liu, Wen; Williams, Michael J. et al.

Ingår i Molecules, 2022

• DOI för Enhanced Toxicity of Bisphenols Together with UV Filters in Water: Identification of Synergy and Antagonism in Three-Component Mixtures
• Ladda ner fulltext (pdf) av Enhanced Toxicity of Bisphenols Together with UV Filters in Water: Identification of Synergy and Antagonism in Three-Component Mixtures

The Statin Target Hmgcr Regulates Energy Metabolism and Food Intake through Central Mechanisms

Williams, Michael J.; Alsehli, Ahmed M.; Gartner, Sarah N.; Clemensson, Laura Emily et al.

Ingår i Cells, 2022

• DOI för The Statin Target Hmgcr Regulates Energy Metabolism and Food Intake through Central Mechanisms
• Ladda ner fulltext (pdf) av The Statin Target Hmgcr Regulates Energy Metabolism and Food Intake through Central Mechanisms

Can Exposure to Environmental Pollutants Be Associated with Less Effective Chemotherapy in Cancer Patients?

Lagunas-Rangel, Francisco Alejandro; Liu, Wen; Schiöth, Helgi B.

Ingår i International Journal of Environmental Research and Public Health, s. 2064-2064, 2022

• DOI för Can Exposure to Environmental Pollutants Be Associated with Less Effective Chemotherapy in Cancer Patients?
• Ladda ner fulltext (pdf) av Can Exposure to Environmental Pollutants Be Associated with Less Effective Chemotherapy in Cancer Patients?

Misdiagnosis of diabetic foot ulcer in patients with undiagnosed skin malignancies

Lyundup, Alexey V; Balyasin, Maxim V; Maksimova, Nadezhda V; Kovina, Marina V et al.

Ingår i International Wound Journal, s. 871-887, 2022

• DOI för Misdiagnosis of diabetic foot ulcer in patients with undiagnosed skin malignancies
• Ladda ner fulltext (pdf) av Misdiagnosis of diabetic foot ulcer in patients with undiagnosed skin malignancies

Statins Induce Locomotion and Muscular Phenotypes in Drosophila melanogaster That Are Reminiscent of Human Myopathy: Evidence for the Role of the Chloride Channel Inhibition in the Muscular Phenotypes

Al-Sabri, Mohamed H.; Behare, Neha; Alsehli, Ahmed M.; Berkins, Samuel et al.

Ingår i Cells, 2022

• DOI för Statins Induce Locomotion and Muscular Phenotypes in Drosophila melanogaster That Are Reminiscent of Human Myopathy: Evidence for the Role of the Chloride Channel Inhibition in the Muscular Phenotypes
• Ladda ner fulltext (pdf) av Statins Induce Locomotion and Muscular Phenotypes in Drosophila melanogaster That Are Reminiscent of Human Myopathy: Evidence for the Role of the Chloride Channel Inhibition in the Muscular Phenotypes

Triple drug therapy with GABA, sitagliptin, and omeprazole prevents type 1 diabetes onset and promotes its reversal in non-obese diabetic mice

Lagunas-Rangel, Francisco Alejandro; Koshelev, Daniil; Nedorubov, Andrej; Kosheleva, Liudmila et al.

Ingår i Frontiers in Endocrinology, 2022

• DOI för Triple drug therapy with GABA, sitagliptin, and omeprazole prevents type 1 diabetes onset and promotes its reversal in non-obese diabetic mice
• Ladda ner fulltext (pdf) av Triple drug therapy with GABA, sitagliptin, and omeprazole prevents type 1 diabetes onset and promotes its reversal in non-obese diabetic mice

A simple high-throughput method for automated detection of Drosophila melanogaster light-dependent behaviours

Moulin, Thiago; Dey, Sovik; Dashi, Giovanna; Li, Lei et al.

Ingår i BMC Biology, 2022

• DOI för A simple high-throughput method for automated detection of Drosophila melanogaster light-dependent behaviours
• Ladda ner fulltext (pdf) av A simple high-throughput method for automated detection of Drosophila melanogaster light-dependent behaviours

GHSR controls food deprivation-induced activation of CRF neurons of the hypothalamic paraventricular nucleus in a LEAP2-dependent manner

Fernandez, Gimena; Cabral, Agustina; De Francesco, Pablo N.; Uriarte, Maia et al.

Ingår i Cellular and Molecular Life Sciences (CMLS), 2022

• DOI för GHSR controls food deprivation-induced activation of CRF neurons of the hypothalamic paraventricular nucleus in a LEAP2-dependent manner

Identification of specific gene methylation patterns during motor neuron differentiation from spinal muscular atrophy patient-derived iPSC

Maretina, M. A.; Valetdinova, K. R.; Tsyganova, N. A.; Egorova, A. A. et al.

Ingår i Gene, 2022

• DOI för Identification of specific gene methylation patterns during motor neuron differentiation from spinal muscular atrophy patient-derived iPSC

Association of Diligence and Sociability with Stroke: A UK Biobank Study on Personality Proxies

de Ruijter, Markus J. T.; Dahlén, Amelia; Rukh, Gull; Schiöth, Helgi B.

Ingår i FRONTIERS IN BIOSCIENCE-LANDMARK, 2022

• DOI för Association of Diligence and Sociability with Stroke: A UK Biobank Study on Personality Proxies
• Ladda ner fulltext (pdf) av Association of Diligence and Sociability with Stroke: A UK Biobank Study on Personality Proxies

Dendritic spine density changes and homeostatic synaptic scaling: a meta-analysis of animal studies

Moulin, Thiago; Rayêe, Danielle; Schiöth, Helgi B.

Ingår i Neural Regeneration Research, s. 20-24, 2022

• DOI för Dendritic spine density changes and homeostatic synaptic scaling: a meta-analysis of animal studies
• Ladda ner fulltext (pdf) av Dendritic spine density changes and homeostatic synaptic scaling: a meta-analysis of animal studies

Migraine and gastrointestinal disorders in middle and old age: A UK Biobank study

Welander, Nike Zoe; Olivo, Gaia; Pisanu, Claudia; Rukh, Gull et al.

Ingår i Brain and Behavior, 2021

• DOI för Migraine and gastrointestinal disorders in middle and old age: A UK Biobank study
• Ladda ner fulltext (pdf) av Migraine and gastrointestinal disorders in middle and old age: A UK Biobank study

Major sex differences in migraine prevalence among occupational categories: a cross-sectional study using UK Biobank

Affatato, Oreste; Miguet, Maud; Schiöth, Helgi B.; Mwinyi, Jessica

Ingår i Journal of Headache and Pain, 2021

• DOI för Major sex differences in migraine prevalence among occupational categories: a cross-sectional study using UK Biobank
• Ladda ner fulltext (pdf) av Major sex differences in migraine prevalence among occupational categories: a cross-sectional study using UK Biobank

Migraine as a risk factor for mixed symptoms of peripartum depression and anxiety in late pregnancy: A prospective cohort study.

Welander, Nike Zoe; Mwinyi, Jessica; Asif, Sana; Schiöth, Helgi Birgir et al.

Ingår i Journal of Affective Disorders, s. 733-739, 2021

• DOI för Migraine as a risk factor for mixed symptoms of peripartum depression and anxiety in late pregnancy: A prospective cohort study.
• Ladda ner fulltext (pdf) av Migraine as a risk factor for mixed symptoms of peripartum depression and anxiety in late pregnancy: A prospective cohort study.

Depression and Vegetarians: Association between Dietary Vitamin B6, B12 and Folate Intake and Global and Subcortical Brain Volumes

Berkins, Samuel; Schiöth, Helgi B.; Rukh, Gull

Ingår i Nutrients, 2021

• DOI för Depression and Vegetarians: Association between Dietary Vitamin B6, B12 and Folate Intake and Global and Subcortical Brain Volumes
• Ladda ner fulltext (pdf) av Depression and Vegetarians: Association between Dietary Vitamin B6, B12 and Folate Intake and Global and Subcortical Brain Volumes

HPA axis dysregulation is associated with differential methylation of CpG-sites in related genes

Chatzittofis, Andreas; Bostrom, Adrian Desai E.; Ciuculete, Diana-Maria; Oberg, Katarina Gorts et al.

Ingår i Scientific Reports, 2021

• DOI för HPA axis dysregulation is associated with differential methylation of CpG-sites in related genes
• Ladda ner fulltext (pdf) av HPA axis dysregulation is associated with differential methylation of CpG-sites in related genes

Time spent outdoors and risk of myocardial infarction and stroke in middle and old aged adults: Results from the UK Biobank prospective cohort

Miguet, Maud; Venetis, Sotirios; Rukh, Gull; Lind, Lars et al.

Ingår i Environmental Research, 2021

• DOI för Time spent outdoors and risk of myocardial infarction and stroke in middle and old aged adults: Results from the UK Biobank prospective cohort
• Ladda ner fulltext (pdf) av Time spent outdoors and risk of myocardial infarction and stroke in middle and old aged adults: Results from the UK Biobank prospective cohort

Multidrug Resistance Like Protein 1 Activity in Malpighian Tubules Regulates Lipid Homeostasis in Drosophila

Liu, Wen; Cao, Hao; Kimari, Moses; Maronitis, Georgios et al.

Ingår i Membranes, 2021

• DOI för Multidrug Resistance Like Protein 1 Activity in Malpighian Tubules Regulates Lipid Homeostasis in Drosophila
• Ladda ner fulltext (pdf) av Multidrug Resistance Like Protein 1 Activity in Malpighian Tubules Regulates Lipid Homeostasis in Drosophila

Characterization of five transmembrane proteins: With focus on the Tweety, Sidoreflexin, and YIP1 domain families

Attwood, Misty M.; Schiöth, Helgi B.

Ingår i Frontiers in Cell and Developmental Biology, 2021

• DOI för Characterization of five transmembrane proteins: With focus on the Tweety, Sidoreflexin, and YIP1 domain families
• Ladda ner fulltext (pdf) av Characterization of five transmembrane proteins: With focus on the Tweety, Sidoreflexin, and YIP1 domain families

Differential associations of statin treatment and polymorphism in genes coding for HMGCR and PCSK9 to risk for insomnia

Alsehli, Ahmed M.; Clemensson, Laura Emily; Rukh, Gull; Ciuculete, Diana-Maria et al.

Ingår i Frontiers in Bioscience-Landmark, s. 1453-1463, 2021

• DOI för Differential associations of statin treatment and polymorphism in genes coding for HMGCR and PCSK9 to risk for insomnia
• Ladda ner fulltext (pdf) av Differential associations of statin treatment and polymorphism in genes coding for HMGCR and PCSK9 to risk for insomnia

BCNNM: A Framework for in silico Neural Tissue Development Modeling

Bozhko, Dmitrii V.; Galumov, Georgii K.; Polovian, Aleksandr I.; Kolchanova, Sofiia M. et al.

Ingår i Frontiers in Computational Neuroscience, 2021

• DOI för BCNNM: A Framework for in silico Neural Tissue Development Modeling
• Ladda ner fulltext (pdf) av BCNNM: A Framework for in silico Neural Tissue Development Modeling

Toll-like receptor 4 methylation grade is linked to depressive symptom severity

Rasmusson, Annica J.; Gallwitz, Maike; Soltanabadi, Bardia; Ciuculete, Diana-Maria et al.

Ingår i Translational Psychiatry, 2021

• DOI för Toll-like receptor 4 methylation grade is linked to depressive symptom severity
• Ladda ner fulltext (pdf) av Toll-like receptor 4 methylation grade is linked to depressive symptom severity

LEAP2 Impairs the Capability of the Growth Hormone Secretagogue Receptor to Regulate the Dopamine 2 Receptor Signaling

Mustafá, Emilio R.; Cordisco González, Santiago; Damian, Marjorie; Cantel, Sonia et al.

Ingår i Frontiers in Pharmacology, 2021

• DOI för LEAP2 Impairs the Capability of the Growth Hormone Secretagogue Receptor to Regulate the Dopamine 2 Receptor Signaling
• Ladda ner fulltext (pdf) av LEAP2 Impairs the Capability of the Growth Hormone Secretagogue Receptor to Regulate the Dopamine 2 Receptor Signaling

Integrating Statistical and Machine-Learning Approach for Meta-Analysis of Bisphenol A-Exposure Datasets Reveals Effects on Mouse Gene Expression within Pathways of Apoptosis and Cell Survival

Lukashina, Nina; Williams, Michael J.; Kartysheva, Elena; Virko, Elizaveta et al.

Ingår i International Journal of Molecular Sciences, 2021

• DOI för Integrating Statistical and Machine-Learning Approach for Meta-Analysis of Bisphenol A-Exposure Datasets Reveals Effects on Mouse Gene Expression within Pathways of Apoptosis and Cell Survival
• Ladda ner fulltext (pdf) av Integrating Statistical and Machine-Learning Approach for Meta-Analysis of Bisphenol A-Exposure Datasets Reveals Effects on Mouse Gene Expression within Pathways of Apoptosis and Cell Survival

Identification of synergistic and antagonistic actions of environmental pollutants: Bisphenols A, S and F in the presence of DEP, DBP, BADGE and BADGE center dot 2HCl in three component mixtures

Jatkowska, Natalia; Kudlak, Blazej; Lewandowska, Patrycja; Liu, Wen et al.

Ingår i Science of the Total Environment, 2021

• DOI för Identification of synergistic and antagonistic actions of environmental pollutants: Bisphenols A, S and F in the presence of DEP, DBP, BADGE and BADGE center dot 2HCl in three component mixtures

Dibutyl phthalate disrupts conserved circadian rhythm in Drosophila and human cells

Liu, Wen; Cao, Hao; Liao, Sifang; Kudlak, Blazej et al.

Ingår i Science of the Total Environment, 2021

• DOI för Dibutyl phthalate disrupts conserved circadian rhythm in Drosophila and human cells
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The Potential Effect of Insulin on AChE and Its Interactions with Rivastigmine In Vitro

Jamshidnejad-Tosaramandani, Tahereh; Kashanian, Soheila; Babaei, Mahsa; Al-Sabri, Mohamed et al.

Ingår i Pharmaceuticals, 2021

• DOI för The Potential Effect of Insulin on AChE and Its Interactions with Rivastigmine In Vitro
• Ladda ner fulltext (pdf) av The Potential Effect of Insulin on AChE and Its Interactions with Rivastigmine In Vitro

Ghrelin restores memory impairment following olfactory bulbectomy in mice by activating hippocampal NMDA1 and MAPK1 gene expression

Bianconi, Santiago; Poretti, María Belén; Rodriguez, Paula; Maestri, Giulia et al.

Ingår i Behavioural Brain Research, 2021

• DOI för Ghrelin restores memory impairment following olfactory bulbectomy in mice by activating hippocampal NMDA1 and MAPK1 gene expression

Trends in kinase drug discovery: targets, indications and inhibitor design

Attwood, Misty M.; Fabbro, Doriano; Sokolov, Aleksandr V.; Knapp, Stefan et al.

Ingår i Nature reviews. Drug discovery, s. 839-861, 2021

• DOI för Trends in kinase drug discovery: targets, indications and inhibitor design

A Multilab Replication of the Ego Depletion Effect

Dang, Junhua; Barker, Paul; Baumert, Anna; Bentvelzen, Margriet et al.

Ingår i Social Psychology and Personality Science, s. 14-24, 2021

• DOI för A Multilab Replication of the Ego Depletion Effect
• Ladda ner fulltext (pdf) av A Multilab Replication of the Ego Depletion Effect

Differentiation of two human neuroblastoma cell lines alters SV2 expression patterns

Lekholm, Emilia; Ceder, Mikaela M.; Forsberg, Erica C.; Schiöth, Helgi B. et al.

Ingår i Cellular & Molecular Biology Letters (Druk), 2021

• DOI för Differentiation of two human neuroblastoma cell lines alters SV2 expression patterns
• Ladda ner fulltext (pdf) av Differentiation of two human neuroblastoma cell lines alters SV2 expression patterns

The Beauty of the Zero: Replications and Extensions of the Hidden-Zero Effect in Delay Discounting Tasks

Dang, Junhua; Liu, Xiaoping; Xiao, Shanshan; Mao, Lihua et al.

Ingår i Social Psychology and Personality Science, s. 544-549, 2021

• DOI för The Beauty of the Zero: Replications and Extensions of the Hidden-Zero Effect in Delay Discounting Tasks
• Ladda ner fulltext (pdf) av The Beauty of the Zero: Replications and Extensions of the Hidden-Zero Effect in Delay Discounting Tasks

Association between migraine prevalence, treatment with proton-pump inhibitors and CYP2C19 phenotypes in UK Biobank

Pisanu, Claudia; Welander, Nike Zoe; Rukh, Gull; Schiöth, Helgi B. et al.

Ingår i Biomedicine and Pharmacotherapy, 2021

• DOI för Association between migraine prevalence, treatment with proton-pump inhibitors and CYP2C19 phenotypes in UK Biobank
• Ladda ner fulltext (pdf) av Association between migraine prevalence, treatment with proton-pump inhibitors and CYP2C19 phenotypes in UK Biobank

The Drosophila melanogaster Levodopa-Induced Depression Model Exhibits Negative Geotaxis Deficits and Differential Gene Expression in Males and Females

Moulin, Thiago; Ferro, Federico; Hoyer, Angela; Cheung, Pierre et al.

Ingår i Frontiers in Neuroscience, 2021

• DOI för The Drosophila melanogaster Levodopa-Induced Depression Model Exhibits Negative Geotaxis Deficits and Differential Gene Expression in Males and Females
• Ladda ner fulltext (pdf) av The Drosophila melanogaster Levodopa-Induced Depression Model Exhibits Negative Geotaxis Deficits and Differential Gene Expression in Males and Females

Important gender differences in psychosomatic and school-related complaints in relation to adolescent weight status

Brooks, Samantha J.; Feldman, Inna; Schiöth, Helgi B.; Titova, Olga E

Ingår i Scientific Reports, 2021

• DOI för Important gender differences in psychosomatic and school-related complaints in relation to adolescent weight status
• Ladda ner fulltext (pdf) av Important gender differences in psychosomatic and school-related complaints in relation to adolescent weight status

Differential DNA methylation of the genes for amyloid precursor protein, tau and neurofilaments in human traumatic brain injury

Abu Hamdeh, Sami; Ciuculete, Diana-Maria; Sarkisyan, Daniil; Bakalkin, Georgy et al.

Ingår i Journal of Neurotrauma, s. 1679-1688, 2021

• DOI för Differential DNA methylation of the genes for amyloid precursor protein, tau and neurofilaments in human traumatic brain injury

Recent developments of HDAC inhibitors: Emerging indications and novel molecules

Bondarev, Andrey D; Attwood, Misty M.; Jonsson, Jörgen; Chubarev, Vladimir N et al.

Ingår i British Journal of Clinical Pharmacology, s. 4577-4597, 2021

• DOI för Recent developments of HDAC inhibitors: Emerging indications and novel molecules
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Pharmacological treatment of migraine: Drug classes, mechanisms of action, clinical trials and new treatments

Zobdeh, Farzin; Ben Kraiem, Aziza; Attwood, Misty M.; Chubarev, Vladimir N et al.

Ingår i British Journal of Pharmacology, s. 4588-4607, 2021

• DOI för Pharmacological treatment of migraine: Drug classes, mechanisms of action, clinical trials and new treatments
• Ladda ner fulltext (pdf) av Pharmacological treatment of migraine: Drug classes, mechanisms of action, clinical trials and new treatments

Neural activation of anxiety and depression in children and young people: A systematic meta-analysis of fMRI studies

Ashworth, Emma; Brooks, Samantha; Schiöth, Helgi B.

Ingår i Psychiatry Research, 2021

• DOI för Neural activation of anxiety and depression in children and young people: A systematic meta-analysis of fMRI studies
• Ladda ner fulltext (pdf) av Neural activation of anxiety and depression in children and young people: A systematic meta-analysis of fMRI studies

Assessment of the granulation process effect on morpho-anatomical features and biologically active substances composition of senna leaves

Trifonova, Olga; Evdokimova, Olga; Prokofieva, Vera; Schiöth, Helgi B. et al.

Ingår i Farmacia, s. 44-50, 2021

• DOI för Assessment of the granulation process effect on morpho-anatomical features and biologically active substances composition of senna leaves

Classification of Trispanins: A Diverse Group of Proteins That Function in Membrane Synthesis and Transport Mechanisms

Attwood, Misty M.; Schiöth, Helgi B.

Ingår i Frontiers in Cell and Developmental Biology, 2020

• DOI för Classification of Trispanins: A Diverse Group of Proteins That Function in Membrane Synthesis and Transport Mechanisms
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meQTL and ncRNA functional analyses of 102 GWAS-SNPs associated with depression implicate HACE1 and SHANK2 genes

Ciuculete, Diana-Maria; Voisin, Sarah; Kular, Lara; Jonsson, Jörgen et al.

Ingår i Clinical Epigenetics, 2020

• DOI för meQTL and ncRNA functional analyses of 102 GWAS-SNPs associated with depression implicate HACE1 and SHANK2 genes
• Ladda ner fulltext (pdf) av meQTL and ncRNA functional analyses of 102 GWAS-SNPs associated with depression implicate HACE1 and SHANK2 genes

Hypermethylation-associated downregulation of microRNA-4456 in hypersexual disorder with putative influence on oxytocin signalling: A DNA methylation analysis of miRNA genes

Boström, Adrian; Chatzittofis, Andreas; Ciuculete, Diana-Maria; Flanagan, John N. et al.

Ingår i Epigenetics, s. 145-160, 2020

• DOI för Hypermethylation-associated downregulation of microRNA-4456 in hypersexual disorder with putative influence on oxytocin signalling: A DNA methylation analysis of miRNA genes
• Ladda ner fulltext (pdf) av Hypermethylation-associated downregulation of microRNA-4456 in hypersexual disorder with putative influence on oxytocin signalling: A DNA methylation analysis of miRNA genes

Draft genome sequences of Hirudo medicinalis and salivary transcriptome of three closely related medicinal leeches

Babenko, Vladislav V.; Podgorny, Oleg; Manuvera, Valentin A.; Kasianov, Artem S. et al.

Ingår i BMC Genomics, 2020

• DOI för Draft genome sequences of Hirudo medicinalis and salivary transcriptome of three closely related medicinal leeches
• Ladda ner fulltext (pdf) av Draft genome sequences of Hirudo medicinalis and salivary transcriptome of three closely related medicinal leeches

Personality, lifestyle and job satisfaction: causal association between neuroticism and job satisfaction using Mendelian randomisation in the UK biobank cohort

Rukh, Gull; Dang, Junhua; Olivo, Gaia; Ciuculete, Diana-Maria et al.

Ingår i Translational Psychiatry, 2020

• DOI för Personality, lifestyle and job satisfaction: causal association between neuroticism and job satisfaction using Mendelian randomisation in the UK biobank cohort
• Ladda ner fulltext (pdf) av Personality, lifestyle and job satisfaction: causal association between neuroticism and job satisfaction using Mendelian randomisation in the UK biobank cohort

Excitability, synaptic balance, and addiction: The homeostatic dynamics of ionotropic glutamatergic receptors in VTA after cocaine exposure

Moulin, Thiago; Schiöth, Helgi B.

Ingår i Behavioral and Brain Functions, 2020

• DOI för Excitability, synaptic balance, and addiction: The homeostatic dynamics of ionotropic glutamatergic receptors in VTA after cocaine exposure
• Ladda ner fulltext (pdf) av Excitability, synaptic balance, and addiction: The homeostatic dynamics of ionotropic glutamatergic receptors in VTA after cocaine exposure

Association between sleep duration and executive function differs between diabetic and non-diabetic middle-aged and older adults.

Titova, Olga E; Lindberg, Eva; Tan, Xiao; Elmståhl, Sölve et al.

Ingår i Psychoneuroendocrinology, 2020

• DOI för Association between sleep duration and executive function differs between diabetic and non-diabetic middle-aged and older adults.
• Ladda ner fulltext (pdf) av Association between sleep duration and executive function differs between diabetic and non-diabetic middle-aged and older adults.

Associations between chronotype, MTNR1B genotype and risk of type 2 diabetes in UK Biobank

Tan, Xiao; Ciuculete, Diana-Maria; Schiöth, Helgi B.; Benedict, Christian

Ingår i Journal of Internal Medicine, s. 189-196, 2020

• DOI för Associations between chronotype, MTNR1B genotype and risk of type 2 diabetes in UK Biobank

Meal timing and subjective sleep disturbances in older men

van Egmond, Lieve T.; Moulin, Thiago C.; Schiöth, Helgi B.; Cederholm, Tommy et al.

Ingår i Experimental Gerontology, 2020

• DOI för Meal timing and subjective sleep disturbances in older men
• Ladda ner fulltext (pdf) av Meal timing and subjective sleep disturbances in older men

A pharmacogenetic risk score for the evaluation of major depression severity under treatment with antidepressants

Kanders, Sofia H.; Pisanu, Claudia; Bandstein, Marcus; Jonsson, Jörgen et al.

Ingår i Drug development research, s. 102-113, 2020

• DOI för A pharmacogenetic risk score for the evaluation of major depression severity under treatment with antidepressants
• Ladda ner fulltext (pdf) av A pharmacogenetic risk score for the evaluation of major depression severity under treatment with antidepressants

The Cognitive Effects of Statins are Modified by Age

Alsehli, Ahmed M.; Olivo, Gaia; Clemensson, Laura Emily; Williams, Michael J. et al.

Ingår i Scientific Reports, 2020

• DOI för The Cognitive Effects of Statins are Modified by Age
• Ladda ner fulltext (pdf) av The Cognitive Effects of Statins are Modified by Age

Longitudinal DNA methylation changes at MET may alter HGF/c-MET signalling in adolescents at risk for depression

Ciuculete, Diana Maria; Voisin, Sarah; Kular, Lara; Welihinda, Nipuni et al.

Ingår i Epigenetics, s. 646-663, 2020

• DOI för Longitudinal DNA methylation changes at MET may alter HGF/c-MET signalling in adolescents at risk for depression
• Ladda ner fulltext (pdf) av Longitudinal DNA methylation changes at MET may alter HGF/c-MET signalling in adolescents at risk for depression

Is there prejudice from thin air?: Replicating the effect of emotion on automatic intergroup attitudes

Dang, Junhua; Ekim, Zeynep E.; Ohlsson, Sarah; Schiöth, Helgi B.

Ingår i BMC Psychology, 2020

• DOI för Is there prejudice from thin air?: Replicating the effect of emotion on automatic intergroup attitudes
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Important Difference between Occupational Hazard Exposure among Shift Workers and Other Workers; Comparing Workplace before and after 1980

Miguet, Maud; Rukh, Gull; Titova, Olga E; Schiöth, Helgi B.

Ingår i International Journal of Environmental Research and Public Health, 2020

• DOI för Important Difference between Occupational Hazard Exposure among Shift Workers and Other Workers; Comparing Workplace before and after 1980
• Ladda ner fulltext (pdf) av Important Difference between Occupational Hazard Exposure among Shift Workers and Other Workers; Comparing Workplace before and after 1980

Normal Testosterone but Higher Luteinizing Hormone Plasma Levels in Men With Hypersexual Disorder

Chatzittofis, Andreas; Boström, Adrian; Görts Öberg, Katarina; Flanagan, John N. et al.

Ingår i Sexual Medicine, s. 243-250, 2020

• DOI för Normal Testosterone but Higher Luteinizing Hormone Plasma Levels in Men With Hypersexual Disorder
• Ladda ner fulltext (pdf) av Normal Testosterone but Higher Luteinizing Hormone Plasma Levels in Men With Hypersexual Disorder

Major depression subtypes are differentially associated with migraine subtype, prevalence and severity

Pisanu, Claudia; Lundin, Emma; Preisig, Martin; Gholam-Rezaee, Mehdi et al.

Ingår i Cephalalgia, s. 347-356, 2020

• DOI för Major depression subtypes are differentially associated with migraine subtype, prevalence and severity

Exposure to the environmental pollutant bisphenol A diglycidyl ether (BADGE) causes cell over-proliferation in Drosophila

Williams, Michael J.; Cao, Hao; Lindkvist, Therese; Mothes, Tobias J. et al.

Ingår i Environmental Science and Pollution Research, s. 25261-25270, 2020

• DOI för Exposure to the environmental pollutant bisphenol A diglycidyl ether (BADGE) causes cell over-proliferation in Drosophila
• Ladda ner fulltext (pdf) av Exposure to the environmental pollutant bisphenol A diglycidyl ether (BADGE) causes cell over-proliferation in Drosophila

CCAP regulates feeding behavior via the NPF pathway in Drosophila adults

Williams, Michael J.; Akram, Mehwish; Barkauskaite, Deimante; Patil, Sourabh et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 7401-7408, 2020

• DOI för CCAP regulates feeding behavior via the NPF pathway in Drosophila adults

Pharmacological NOS-1 Inhibition Within the Hippocampus Prevented Expression of Cocaine Sensitization: Correlation with Reduced Synaptic Transmission

de la Villarmois, Emilce; Gabach, Laura A.; Bianconi, Santiago; Poretti, Maria Belen et al.

Ingår i Molecular Neurobiology, s. 450-460, 2020

• DOI för Pharmacological NOS-1 Inhibition Within the Hippocampus Prevented Expression of Cocaine Sensitization: Correlation with Reduced Synaptic Transmission

Evidence that genes involved in hedgehog signaling are associated with both bipolar disorder and high BMI

Pisanu, Claudia; Williams, Michael J.; Ciuculete, Diana-Maria; Olivo, Gaia et al.

Ingår i Translational Psychiatry, 2019

• DOI för Evidence that genes involved in hedgehog signaling are associated with both bipolar disorder and high BMI
• Ladda ner fulltext (pdf) av Evidence that genes involved in hedgehog signaling are associated with both bipolar disorder and high BMI

Functional connectivity underlying hedonic response to food in female adolescents with atypical AN: The role of somatosensory and salience networks

Olivo, Gaia; Zhukovsky, Christina; Salonen-Ros, Helena; Larsson, Elna-Marie et al.

Ingår i Translational Psychiatry, 2019

• DOI för Functional connectivity underlying hedonic response to food in female adolescents with atypical AN: The role of somatosensory and salience networks
• Ladda ner fulltext (pdf) av Functional connectivity underlying hedonic response to food in female adolescents with atypical AN: The role of somatosensory and salience networks

Association Between Self-Reported Sleep Duration and Body Composition in Middle-Aged and Older Adults

Tan, Xiao; Titova, Olga E.; Lindberg, Eva; Elmståhl, Sölve et al.

Ingår i Journal of Clinical Sleep Medicine (JCSM), s. 431-435, 2019

• DOI för Association Between Self-Reported Sleep Duration and Body Composition in Middle-Aged and Older Adults

A single night of sleep loss impairs objective but not subjective working memory performance in a sex-dependent manner

Rångtell, Frida H; Karamchedu, Swathy; Andersson, Peter; Liethof, Lisanne et al.

Ingår i Journal of Sleep Research, 2019

• DOI för A single night of sleep loss impairs objective but not subjective working memory performance in a sex-dependent manner
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Growth hormone secretagogue receptor signalling affects high-fat intake independently of plasma levels of ghrelin and LEAP2, in a 4-day binge eating model

Paula Cornejo, Maria; Castrogiovanni, Daniel; Schiöth, Helgi B.; Reynaldo, Mirta et al.

Ingår i Journal of neuroendocrinology, 2019

• DOI för Growth hormone secretagogue receptor signalling affects high-fat intake independently of plasma levels of ghrelin and LEAP2, in a 4-day binge eating model

The polyamine transporter Slc18b1(VPAT) is important for both short and long time memory and for regulation of polyamine content in the brain.

Fredriksson, Robert; Sreedharan, Smitha; Nordenankar, Karin; Alsiö, Johan et al.

Ingår i PLOS Genetics, 2019

• DOI för The polyamine transporter Slc18b1(VPAT) is important for both short and long time memory and for regulation of polyamine content in the brain.
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Preserved white matter microstructure in adolescent patients with atypical anorexia nervosa

Olivo, Gaia; Swenne, Ingemar; Zhukovsky, Christina; Tuunainen, Anna-Kaisa et al.

Ingår i International Journal of Eating Disorders, s. 166-174, 2019

• DOI för Preserved white matter microstructure in adolescent patients with atypical anorexia nervosa
• Ladda ner fulltext (pdf) av Preserved white matter microstructure in adolescent patients with atypical anorexia nervosa

Plasma levels of leptin and adiponectin and depressive symptoms in young adults

Syk, Mikaela; Ellström, Sofie; Mwinyi, Jessica; Schiöth, Helgi B. et al.

Ingår i Psychiatry Research, s. 1-7, 2019

• DOI för Plasma levels of leptin and adiponectin and depressive symptoms in young adults
• Ladda ner fulltext (pdf) av Plasma levels of leptin and adiponectin and depressive symptoms in young adults

Low neuroticism and cognitive performance are differently associated to overweight and obesity: A cross-sectional and longitudinal UK Biobank study.

Olivo, Gaia; Gour, Shaili; Schiöth, Helgi B.

Ingår i Psychoneuroendocrinology, s. 167-174, 2019

• DOI för Low neuroticism and cognitive performance are differently associated to overweight and obesity: A cross-sectional and longitudinal UK Biobank study.
• Ladda ner fulltext (pdf) av Low neuroticism and cognitive performance are differently associated to overweight and obesity: A cross-sectional and longitudinal UK Biobank study.

Memory consolidation impairment induced by Interleukin-1 beta is associated with changes in hippocampal structural plasticity

Herrera, Guadalupe; Calfa, Gaston; Schiöth, Helgi B.; Lasaga, Mercedes et al.

Ingår i Behavioural Brain Research, 2019

• DOI för Memory consolidation impairment induced by Interleukin-1 beta is associated with changes in hippocampal structural plasticity

Testosterone, luteinizing hormone levels and methylation status in men with hypersexual disorders

Chatzittofis, A.; Boström, Adrian; Öberg, K.; Flanagan, J. et al.

Ingår i European Neuropsychopharmacology, 2019

• DOI för Testosterone, luteinizing hormone levels and methylation status in men with hypersexual disorders

Acute sleep loss results in tissue-specific alterations in genome-wide DNA methylation state and metabolic fuel utilization in humans

Cedernaes, Jonathan; Schonke, Milena; Westholm, Jakub Orzechowski; Mi, Jia et al.

Ingår i Science Advances, 2018

• DOI för Acute sleep loss results in tissue-specific alterations in genome-wide DNA methylation state and metabolic fuel utilization in humans
• Ladda ner fulltext (pdf) av Acute sleep loss results in tissue-specific alterations in genome-wide DNA methylation state and metabolic fuel utilization in humans

Disruption of Accumbens and Thalamic White Matter Connectivity Revealed by Diffusion Tensor Tractography in Young Men with Genetic Risk for Obesity

Olivo, Gaia; Latini, Francesco; Wiemerslage, Lyle; Larsson, Elna-Marie et al.

Ingår i Frontiers in Human Neuroscience, 2018

• DOI för Disruption of Accumbens and Thalamic White Matter Connectivity Revealed by Diffusion Tensor Tractography in Young Men with Genetic Risk for Obesity
• Ladda ner fulltext (pdf) av Disruption of Accumbens and Thalamic White Matter Connectivity Revealed by Diffusion Tensor Tractography in Young Men with Genetic Risk for Obesity

Reduced resting-state connectivity in areas involved in processing of face-related social cues in female adolescents with atypical anorexia nervosa

Olivo, Gaia; Swenne, Ingemar; Zhukovsky, Christina; Tuunainen, Anna-Kaisa et al.

Ingår i Translational Psychiatry, 2018

• DOI för Reduced resting-state connectivity in areas involved in processing of face-related social cues in female adolescents with atypical anorexia nervosa
• Ladda ner fulltext (pdf) av Reduced resting-state connectivity in areas involved in processing of face-related social cues in female adolescents with atypical anorexia nervosa

Altered cerebellar-insular-parietal-cingular subnetwork in adolescents in the earliest stages of anorexia nervosa: a network-based statistic analysis

Gaudio, Santino; Olivo, Gaia; Zobel, Bruno Beomonte; Schiöth, Helgi B.

Ingår i Translational Psychiatry, 2018

• DOI för Altered cerebellar-insular-parietal-cingular subnetwork in adolescents in the earliest stages of anorexia nervosa: a network-based statistic analysis
• Ladda ner fulltext (pdf) av Altered cerebellar-insular-parietal-cingular subnetwork in adolescents in the earliest stages of anorexia nervosa: a network-based statistic analysis

Associations Between the Prevalence of Metabolic Syndrome and Sleep Parameters Vary by Age

Titova, Olga E; Lindberg, Eva; Elmstahl, Solve; Lind, Lars et al.

Ingår i Frontiers in Endocrinology, 2018

• DOI för Associations Between the Prevalence of Metabolic Syndrome and Sleep Parameters Vary by Age
• Ladda ner fulltext (pdf) av Associations Between the Prevalence of Metabolic Syndrome and Sleep Parameters Vary by Age

Self-reported sleep disturbances and prostate cancer morbidity and mortality in Swedish men: A longitudinal study over 40 years

Tan, Xiao; Cedernaes, Jonathan; Forsberg, Lars A.; Schiöth, Helgi B. et al.

Ingår i Journal of Sleep Research, 2018

• DOI för Self-reported sleep disturbances and prostate cancer morbidity and mortality in Swedish men: A longitudinal study over 40 years
• Ladda ner fulltext (pdf) av Self-reported sleep disturbances and prostate cancer morbidity and mortality in Swedish men: A longitudinal study over 40 years

Intranasal insulin in Alzheimer's disease: food for thought

Chapman, Colin D; Schiöth, Helgi B.; Grillo, Claudia A; Benedict, Christian

Ingår i Neuropharmacology, s. 196-201, 2018

• DOI för Intranasal insulin in Alzheimer's disease: food for thought
• Ladda ner fulltext (pdf) av Intranasal insulin in Alzheimer's disease: food for thought

Changes in methylation within the STK32B promoter are associated with an increased risk for generalized anxiety disorder in adolescents

Ciuculete, Diana-Maria; Boström, Adrian E.; Tuunainen, Anna-Kaisa; Sohrabi, Farah et al.

Ingår i Journal of Psychiatric Research, s. 44-51, 2018

• DOI för Changes in methylation within the STK32B promoter are associated with an increased risk for generalized anxiety disorder in adolescents
• Ladda ner fulltext (pdf) av Changes in methylation within the STK32B promoter are associated with an increased risk for generalized anxiety disorder in adolescents

Effects of dietary omega-3 PUFAs on growth and development: Somatic, neurobiological and reproductive functions in a murine model.

Bianconi, Santiago; Santillán, María E; Solís, María Del Rosario; Martini, Ana C et al.

Ingår i Journal of Nutritional Biochemistry, s. 82-90, 2018

• DOI för Effects of dietary omega-3 PUFAs on growth and development: Somatic, neurobiological and reproductive functions in a murine model.

Atypical anorexia nervosa is not related to brain structural changes in newly diagnosed adolescent patients.

Olivo, Gaia; Solstrand Dahlberg, Linda; Wiemerslage, Lyle; Swenne, Ingemar et al.

Ingår i International Journal of Eating Disorders, s. 39-45, 2018

• DOI för Atypical anorexia nervosa is not related to brain structural changes in newly diagnosed adolescent patients.

Epigenetic Changes in the CRH Gene are Related to Severity of Suicide Attempt and a General Psychiatric Risk Score in Adolescents

Jokinen, Jussi; Boström, Adrian; Dadfar, Ali; Ciuculete, Diana-Maria et al.

Ingår i EBioMedicine, s. 123-133, 2018

• DOI för Epigenetic Changes in the CRH Gene are Related to Severity of Suicide Attempt and a General Psychiatric Risk Score in Adolescents
• Ladda ner fulltext (pdf) av Epigenetic Changes in the CRH Gene are Related to Severity of Suicide Attempt and a General Psychiatric Risk Score in Adolescents

Orphan Drugs and Their Impact on Pharmaceutical Development

Attwood, Misty M.; Rask-Andersen, Mathias; Schiöth, Helgi B.

Ingår i TIPS - Trends in Pharmacological Sciences, 2018

• DOI för Orphan Drugs and Their Impact on Pharmaceutical Development

Heterologous Expression, Biosynthetic Studies, and Ecological Function of the Selective Gq-Signaling Inhibitor FR900359

Crüsemann, Max; Reher, Raphael; Schamari, Isabella; Brachmann, Alexander O et al.

Ingår i Angewandte Chemie International Edition, s. 836-840, 2018

• DOI för Heterologous Expression, Biosynthetic Studies, and Ecological Function of the Selective Gq-Signaling Inhibitor FR900359

Diffusion tensor imaging and tractography of the white matter in normal aging: The rate-of-change differs between segments within tracts

Mårtensson, Johanna; Lätt, J.; Åhs, Fredrik; Fredriksson, Mats et al.

Ingår i Magnetic Resonance Imaging, s. 113-119, 2018

• DOI för Diffusion tensor imaging and tractography of the white matter in normal aging: The rate-of-change differs between segments within tracts

IL-1 beta reduces GluAl phosphorylation and its surface expression during memory reconsolidation and cc-melanocyte-stimulating hormone can modulate these effects

Machado, Ivana; Schiöth, Helgi B.; Lasaga, Mercedes; Scimonelli, Teresa

Ingår i Neuropharmacology, s. 314-323, 2018

• DOI för IL-1 beta reduces GluAl phosphorylation and its surface expression during memory reconsolidation and cc-melanocyte-stimulating hormone can modulate these effects

Reproductive performance of male mice after hypothalamic ghrelin administration

Belen Poretti, Maria; Frautschi, Camila; Luque, Eugenia; Bianconi, Santiago et al.

Ingår i Reproduction, s. 121-132, 2018

• DOI för Reproductive performance of male mice after hypothalamic ghrelin administration

Plasma stearoyl-CoA desaturase activity indices and bile acid concentrations after a low-fat meal: association with a genetic variant in the FTO gene

Skuladottir, Gudrun Valgerdur; Oskarsdottir, Harpa; Pisanu, Claudia; Sjodin, Marcus et al.

Ingår i Diabetes, Metabolic Syndrome and Obesity, s. 611-618, 2018

• DOI för Plasma stearoyl-CoA desaturase activity indices and bile acid concentrations after a low-fat meal: association with a genetic variant in the FTO gene
• Ladda ner fulltext (pdf) av Plasma stearoyl-CoA desaturase activity indices and bile acid concentrations after a low-fat meal: association with a genetic variant in the FTO gene

Significantly altered peripheral blood cell DNA methylation profile as a result of immediate effect of metformin use in healthy individuals

Elbere, Ilze; Silamikelis, Ivars; Ustinova, Monta; Kalnina, Ineta et al.

Ingår i Clinical Epigenetics, 2018

• DOI för Significantly altered peripheral blood cell DNA methylation profile as a result of immediate effect of metformin use in healthy individuals
• Ladda ner fulltext (pdf) av Significantly altered peripheral blood cell DNA methylation profile as a result of immediate effect of metformin use in healthy individuals

Severity of Suicide Attempt is Associated With Epigenetic and Transcriptional Changes in the CYP2D6 Gene

Jokinen, Jussi; Boström, Adrian; Åsberg, Marie; Schiöth, Helgi B.

Ingår i Biological Psychiatry, 2018

• DOI för Severity of Suicide Attempt is Associated With Epigenetic and Transcriptional Changes in the CYP2D6 Gene

Inflammatory markers in late pregnancy in association with postpartum depression-A nested case-control study.

Bränn, Emma; Papadopoulos, Fotios; Fransson, Emma; White, Richard et al.

Ingår i Psychoneuroendocrinology, s. 146-159, 2017

• DOI för Inflammatory markers in late pregnancy in association with postpartum depression-A nested case-control study.
• Ladda ner fulltext (pdf) av Inflammatory markers in late pregnancy in association with postpartum depression-A nested case-control study.

A DNA methylation site within the KLF13 gene is associated with orexigenic processes based on neural responses and ghrelin levels

Wiemerslage, Lyle; Islam, R.; van der Kamp, C; Cao, Hao et al.

Ingår i International Journal of Obesity, s. 990-994, 2017

• DOI för A DNA methylation site within the KLF13 gene is associated with orexigenic processes based on neural responses and ghrelin levels

A genetic risk score is differentially associated with migraine with and without aura

Pisanu, Claudia; Preisig, Martin; Castelao, Enrique; Glaus, Jennifer et al.

Ingår i Human Genetics, s. 999-1008, 2017

• DOI för A genetic risk score is differentially associated with migraine with and without aura
• Ladda ner fulltext (pdf) av A genetic risk score is differentially associated with migraine with and without aura

Response to Leusink et al.

Ciuculete, Diana-Maria; Schiöth, Helgi B.; Mwinyi, Jessica

Ingår i Clinical Genetics, s. 566-566, 2017

• DOI för Response to Leusink et al.

Limbic-thalamo-cortical projections and reward-related circuitry integrity affects eating behavior: A longitudinal DTI study in adolescents with restrictive eating disorders

Olivo, Gaia; Wiemerslage, Lyle; Swenne, Ingemar; Zhukowsky, Christina et al.

Ingår i PLOS ONE, 2017

• DOI för Limbic-thalamo-cortical projections and reward-related circuitry integrity affects eating behavior: A longitudinal DTI study in adolescents with restrictive eating disorders
• Ladda ner fulltext (pdf) av Limbic-thalamo-cortical projections and reward-related circuitry integrity affects eating behavior: A longitudinal DTI study in adolescents with restrictive eating disorders

A methylome-wide mQTL analysis reveals associations of methylation sites with GAD1 and HDAC3 SNPs and a general psychiatric risk score

Ciuculete, Diana-Maria; Boström, Adrian E.; Voisin, Sarah; Philipps, H. et al.

Ingår i Translational Psychiatry, 2017

• DOI för A methylome-wide mQTL analysis reveals associations of methylation sites with GAD1 and HDAC3 SNPs and a general psychiatric risk score
• Ladda ner fulltext (pdf) av A methylome-wide mQTL analysis reveals associations of methylation sites with GAD1 and HDAC3 SNPs and a general psychiatric risk score

Adolescents Newly Diagnosed with Eating Disorders have Structural Differences in Brain Regions linked with Eating Disorder Symptoms

Solstrand Dahlberg, Linda; Wiemerslage, Lyle; Swenne, Ingemar; Aronsson, Marianne et al.

Ingår i Nordic Journal of Psychiatry, s. 188-196, 2017

• DOI för Adolescents Newly Diagnosed with Eating Disorders have Structural Differences in Brain Regions linked with Eating Disorder Symptoms

Lower inflammatory markers in women with antenatal depression brings the M1/M2 balance into focus from a new direction

Edvinsson, Åsa; Bränn, Emma; Hellgren, Charlotte; Freyhult, Eva et al.

Ingår i Psychoneuroendocrinology, s. 15-25, 2017

• DOI för Lower inflammatory markers in women with antenatal depression brings the M1/M2 balance into focus from a new direction

A genetic risk score is significantly associated with statin therapy response in the elderly population

Ciuculete, Diana-Maria; Bandstein, Marcus; Benedict, Christian; Waeber, G. et al.

Ingår i Clinical Genetics, s. 379-385, 2017

• DOI för A genetic risk score is significantly associated with statin therapy response in the elderly population

Sex matters: Report experimenter gender

Chapman, Colin Daniel; Benedict, Christian; Schiöth, Helgi B.

Ingår i Science, s. 916-917, 2017

• DOI för Sex matters: Report experimenter gender

Resting-state brain connectivity changes in obese women after Roux-en-Y gastric bypass surgery: A longitudinal study

Olivo, Gaia; Zhou, Wei; Sundbom, Magnus; Zhukovsky, Christina et al.

Ingår i Scientific Reports, 2017

• DOI för Resting-state brain connectivity changes in obese women after Roux-en-Y gastric bypass surgery: A longitudinal study
• Ladda ner fulltext (pdf) av Resting-state brain connectivity changes in obese women after Roux-en-Y gastric bypass surgery: A longitudinal study

High leptin levels are associated with migraine with aura

Pisanu, Claudia; Preisig, Martin; Castelao, Enrique; Glaus, Jennifer et al.

Ingår i Cephalalgia, s. 435-441, 2017

• DOI för High leptin levels are associated with migraine with aura

Highly diversified expansions shaped the evolution of membrane bound proteins in metazoans

Attwood, Misty M.; Krishnan, Arunkumar; Sällman Almén, Markus; Schiöth, Helgi B.

Ingår i Scientific Reports, 2017

• DOI för Highly diversified expansions shaped the evolution of membrane bound proteins in metazoans
• Ladda ner fulltext (pdf) av Highly diversified expansions shaped the evolution of membrane bound proteins in metazoans

A genetic variant in the catechol-O-methyl transferase (COMT) gene is related to age-dependent differences in the therapeutic effect of calcium-channel blockers

Xu, Jiayue; Boström, Adrian; Saeed, Mohamed; Dubey, Raghvendra K. et al.

Ingår i Medicine, 2017

• DOI för A genetic variant in the catechol-O-methyl transferase (COMT) gene is related to age-dependent differences in the therapeutic effect of calcium-channel blockers

NAFLD is associated with methylation shifts with relevance for the expression of genes involved in lipoprotein particle composition

Mwinyi, Jessica; Boström, Adrian; Pisanu, Claudia; Murphy, Susan K. et al.

Ingår i Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, s. 314-323, 2017

• DOI för NAFLD is associated with methylation shifts with relevance for the expression of genes involved in lipoprotein particle composition

Plasma 1-deoxysphingolipids are early predictors of incident type 2 diabetes mellitus

Mwinyi, Jessica; Boström, Adrian; Fehrer, I.; Othman, A. et al.

Ingår i PLOS ONE, 2017

• DOI för Plasma 1-deoxysphingolipids are early predictors of incident type 2 diabetes mellitus
• Ladda ner fulltext (pdf) av Plasma 1-deoxysphingolipids are early predictors of incident type 2 diabetes mellitus

A MIR4646 associated methylation locus is hypomethylated in adolescent depression

Boström, Adrian; Ciuculete, Diana-Maria; Attwood, Misty M.; Krattinger, Regina et al.

Ingår i Journal of Affective Disorders, s. 117-128, 2017

• DOI för A MIR4646 associated methylation locus is hypomethylated in adolescent depression
• Ladda ner fulltext (pdf) av A MIR4646 associated methylation locus is hypomethylated in adolescent depression

Trends in GPCR drug discovery: new agents, targets and indications

Hauser, Alexander S; Attwood, Misty M.; Rask-Andersen, Mathias; Schiöth, Helgi B. et al.

Ingår i Nature reviews. Drug discovery, s. 829-842, 2017

• DOI för Trends in GPCR drug discovery: new agents, targets and indications

Melanocortin 4 Receptor Constitutive Activity Inhibits L-Type Voltage-Gated Calcium Channels In Neurons

Agosti, F.; Cordisco Gonzalez, S.; Martinez Damonte, V.; Tolosa, M. J. et al.

Ingår i Neuroscience, s. 102-112, 2017

• DOI för Melanocortin 4 Receptor Constitutive Activity Inhibits L-Type Voltage-Gated Calcium Channels In Neurons

The impact of cognitive training in substance use disorder: the effect of working memory training on impulse control in methamphetamine users

Brooks, Samantha J.; Wiemerslage, L; Burch, K H; Maiorana, S A et al.

Ingår i Psychopharmacology, s. 1911-1921, 2017

• DOI för The impact of cognitive training in substance use disorder: the effect of working memory training on impulse control in methamphetamine users
• Ladda ner fulltext (pdf) av The impact of cognitive training in substance use disorder: the effect of working memory training on impulse control in methamphetamine users

A resting-state fMRI study of obese females between pre- and postprandial states before and after bariatric surgery.

Wiemerslage, Lyle; Zhou, Wei; Olivo, Gaia; Stark, Julia et al.

Ingår i European Journal of Neuroscience, s. 333-341, 2017

• DOI för A resting-state fMRI study of obese females between pre- and postprandial states before and after bariatric surgery.

Anxiety Disorders are Associated with Low Socioeconomic Status in Women but Not in Men

Mwinyi, Jessica; Pisanu, Claudia; Castelao, Enrique; Stringhini, Silvia et al.

Ingår i Women's health issues, s. 302-307, 2017

• DOI för Anxiety Disorders are Associated with Low Socioeconomic Status in Women but Not in Men

Chemical probes to potently and selectively inhibit endocannabinoid cellular reuptake

Chicca, Andrea; Nicolussi, Simon; Bartholomäus, Ruben; Blunder, Martina et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2017

• DOI för Chemical probes to potently and selectively inhibit endocannabinoid cellular reuptake

Methylation of Hypothalamic-Pituitary-Adrenal Axis Related Genes in Men with Hypersexual Disorder

Jokinen, Jussi; Boström, Adrian; Chatzittofis, Andreas; Oberg, Katarina Gorts et al.

Ingår i Biological Psychiatry, 2017

• DOI för Methylation of Hypothalamic-Pituitary-Adrenal Axis Related Genes in Men with Hypersexual Disorder

Methylation of HPA axis related genes in men with hypersexual disorder

Jokinen, Jussi; Boström, Adrian E.; Chatzittofis, Andreas; Ciuculete, Diana-Maria et al.

Ingår i Psychoneuroendocrinology, s. 67-73, 2017

• DOI för Methylation of HPA axis related genes in men with hypersexual disorder

Methylation of the HPA axis related genes in men with hypersexual disorder

Jokinen, Jussi; Boström, Adrian; Chatzittofis, Andreas; Oberg, Katarina Gorts et al.

Ingår i Journal of Behavioral Addictions, s. 23-23, 2017

• DOI för Methylation of the HPA axis related genes in men with hypersexual disorder

A genetic variant in proximity to the gene LYPLAL1 is associated with lower hunger feelings and increased weight loss following Roux-en Y gastric bypass surgery

Bandstein, Marcus; Mwinyi, Jessica; Ernst, Barbara; Thurnheer, Martin et al.

Ingår i Scandinavian Journal of Gastroenterology, s. 1050-1055, 2016

• DOI för A genetic variant in proximity to the gene LYPLAL1 is associated with lower hunger feelings and increased weight loss following Roux-en Y gastric bypass surgery
• Ladda ner fulltext (pdf) av A genetic variant in proximity to the gene LYPLAL1 is associated with lower hunger feelings and increased weight loss following Roux-en Y gastric bypass surgery

One-night sleep deprivation induces changes in the DNA methylation and serum activity indices of stearoyl-CoA desaturase in young healthy men

Skuladottir, Gudrun Valgerdur; Nilsson, Emil Karl; Mwinyi, Jessica; Schiöth, Helgi Birgir

Ingår i Lipids in Health and Disease, 2016

• DOI för One-night sleep deprivation induces changes in the DNA methylation and serum activity indices of stearoyl-CoA desaturase in young healthy men
• Ladda ner fulltext (pdf) av One-night sleep deprivation induces changes in the DNA methylation and serum activity indices of stearoyl-CoA desaturase in young healthy men

Higher resting-state activity in reward-related brain circuits in obese versus normal-weight females independent of food intake

Hogenkamp, Pleunie S.; Zhou, Wei; Dahlberg, Linda Solstrand; Stark, J. et al.

Ingår i International Journal of Obesity, s. 1687-1692, 2016

• DOI för Higher resting-state activity in reward-related brain circuits in obese versus normal-weight females independent of food intake
• Ladda ner fulltext (pdf) av Higher resting-state activity in reward-related brain circuits in obese versus normal-weight females independent of food intake

microRNA-192 suppresses the expression of the farnesoid X receptor

Krattinger, Regina; Boström, Adrian; Schiöth, Helgi B.; Thasler, Wolfgang E. et al.

Ingår i American Journal of Physiology - Gastrointestinal and Liver Physiology, 2016

• DOI för microRNA-192 suppresses the expression of the farnesoid X receptor

A genetic risk score is associated with weight loss following Roux-Y gastric bypass surgery

Bandstein, Marcus; Voisin, Sarah; Nilsson, Emil; Schultes, Bernd et al.

Ingår i Obesity Surgery, s. 2183-2189, 2016

• DOI för A genetic risk score is associated with weight loss following Roux-Y gastric bypass surgery
• Ladda ner fulltext (pdf) av A genetic risk score is associated with weight loss following Roux-Y gastric bypass surgery

Longitudinal genome-wide methylation study of Roux-en-Y gastric bypass patients reveals novel CpG sites associated with essential hypertension

Boström, Adrian E.; Mwinyi, Jessica; Voisin, Sarah; Wu, Wenting et al.

Ingår i BMC Medical Genomics, 2016

• DOI för Longitudinal genome-wide methylation study of Roux-en-Y gastric bypass patients reveals novel CpG sites associated with essential hypertension
• Ladda ner fulltext (pdf) av Longitudinal genome-wide methylation study of Roux-en-Y gastric bypass patients reveals novel CpG sites associated with essential hypertension

Epigenomics of Total Acute Sleep Deprivation in Relation to Genome-Wide DNA Methylation Profiles and RNA Expression

Nilsson, Emil K.; Boström, Adrian E.; Mwinyi, Jessica; Schiöth, Helgi B.

Ingår i Omics, s. 334-342, 2016

• DOI för Epigenomics of Total Acute Sleep Deprivation in Relation to Genome-Wide DNA Methylation Profiles and RNA Expression

mRNA GPR162 changes are associated with decreased food intake in rat, and its human genetic variants with impairments in glucose homeostasis in two Swedish cohorts

Caruso, Vanni; Sreedharan, Smitha; Carlini, Valeria P.; Jacobsson, Josefin A. et al.

Ingår i Gene, s. 139-145, 2016

• DOI för mRNA GPR162 changes are associated with decreased food intake in rat, and its human genetic variants with impairments in glucose homeostasis in two Swedish cohorts

Recurrent Sleep Fragmentation Induces Insulin and Neuroprotective Mechanisms in Middle-Aged Flies

Williams, Michael J.; Perland, Emelie; Eriksson, Mikaela M.; Carlsson, Josef et al.

Ingår i Frontiers in Aging Neuroscience, 2016

• DOI för Recurrent Sleep Fragmentation Induces Insulin and Neuroprotective Mechanisms in Middle-Aged Flies
• Ladda ner fulltext (pdf) av Recurrent Sleep Fragmentation Induces Insulin and Neuroprotective Mechanisms in Middle-Aged Flies

Resting-State Bra in and the FTO Obesity Risk Allele: Default Mode, Sensorimotor, and Salience Network Connectivity Underlying Different Somatosensory Integration and Reward Processing between Genotypes

Olivo, Gaia; Wiemerslage, Lyle; Nilsson, Emil K.; Dahlberg, Linda Solstrand et al.

Ingår i Frontiers in Human Neuroscience, 2016

• DOI för Resting-State Bra in and the FTO Obesity Risk Allele: Default Mode, Sensorimotor, and Salience Network Connectivity Underlying Different Somatosensory Integration and Reward Processing between Genotypes
• Ladda ner fulltext (pdf) av Resting-State Bra in and the FTO Obesity Risk Allele: Default Mode, Sensorimotor, and Salience Network Connectivity Underlying Different Somatosensory Integration and Reward Processing between Genotypes

Psychological intervention with working memory training increases basal ganglia volume: A VBM study of inpatient treatment for methamphetamine use

Brooks, S. J.; Burch, K. H.; Maiorana, S. A.; Cocolas, E. et al.

Ingår i NeuroImage, s. 478-491, 2016

• DOI för Psychological intervention with working memory training increases basal ganglia volume: A VBM study of inpatient treatment for methamphetamine use
• Ladda ner fulltext (pdf) av Psychological intervention with working memory training increases basal ganglia volume: A VBM study of inpatient treatment for methamphetamine use

Topology based identification and comprehensive classification of four-transmembrane helix containing proteins (4TMs) in the human genome

Attwood, Misty M.; Krishnan, Arunkumar; Pivotti, Valentina; Yazdi, Samira et al.

Ingår i BMC Genomics, 2016

• DOI för Topology based identification and comprehensive classification of four-transmembrane helix containing proteins (4TMs) in the human genome
• Ladda ner fulltext (pdf) av Topology based identification and comprehensive classification of four-transmembrane helix containing proteins (4TMs) in the human genome

A targeted analysis reveals relevant shifts in the methylation and transcription of genes responsible for bile acid homeostasis and drug metabolism in non-alcoholic fatty liver disease

Schiöth, Helgi B.; Boström, Adrian; Murphy, Susan K.; Erhart, Wiebke et al.

Ingår i BMC Genomics, 2016

• DOI för A targeted analysis reveals relevant shifts in the methylation and transcription of genes responsible for bile acid homeostasis and drug metabolism in non-alcoholic fatty liver disease
• Ladda ner fulltext (pdf) av A targeted analysis reveals relevant shifts in the methylation and transcription of genes responsible for bile acid homeostasis and drug metabolism in non-alcoholic fatty liver disease

Postprandial alterations in whole-blood DNA methylation are mediated by changes in white blood cell composition

Rask-Andersen, Mathias; Bringeland, Nathalie; Nilsson, Emil K.; Bandstein, Marcus et al.

Ingår i American Journal of Clinical Nutrition, s. 518-525, 2016

• DOI för Postprandial alterations in whole-blood DNA methylation are mediated by changes in white blood cell composition

An obesity-associated risk allele within the FTO gene affects human brain activity for areas important for emotion, impulse control and reward in response to food images

Wiemerslage, Lyle; Nilsson, Emil K.; Dahlberg, Linda Solstrand; Ence-Eriksson, Fia et al.

Ingår i European Journal of Neuroscience, s. 1173-1180, 2016

• DOI för An obesity-associated risk allele within the FTO gene affects human brain activity for areas important for emotion, impulse control and reward in response to food images

Association between shift work history and performance on the trail making test in middle-aged and elderly humans: the EpiHealth study

Titova, Olga E; Lindberg, Eva; Elmståhl, Sölve; Lind, Lars et al.

Ingår i Neurobiology of Aging, s. 23-29, 2016

• DOI för Association between shift work history and performance on the trail making test in middle-aged and elderly humans: the EpiHealth study
• Ladda ner fulltext (pdf) av Association between shift work history and performance on the trail making test in middle-aged and elderly humans: the EpiHealth study

Two hours of evening reading on a self-luminous tablet vs. reading a physical book does not alter sleep after daytime bright light exposure

Rångtell, Frida H.; Ekstrand, Emelie; Rapp, Linnea; Lagermalm, Anna et al.

Ingår i Sleep Medicine, s. 111-118, 2016

• DOI för Two hours of evening reading on a self-luminous tablet vs. reading a physical book does not alter sleep after daytime bright light exposure
• Ladda ner fulltext (pdf) av Two hours of evening reading on a self-luminous tablet vs. reading a physical book does not alter sleep after daytime bright light exposure

Learning and sleep-dependent consolidation of spatial and procedural memories are unaltered in young men under a fixed short sleep schedule

Cedernaes, Jonathan; Sand, Filip; Liethof, Lisanne; Lampola, Lauri et al.

Ingår i Neurobiology of Learning and Memory, s. 87-94, 2016

• DOI för Learning and sleep-dependent consolidation of spatial and procedural memories are unaltered in young men under a fixed short sleep schedule
• Ladda ner fulltext (pdf) av Learning and sleep-dependent consolidation of spatial and procedural memories are unaltered in young men under a fixed short sleep schedule

A single night of partial sleep loss impairs fasting insulin sensitivity but does not affect cephalic phase insulin release in young men

Cedernaes, Jonathan; Lampola, Lauri; Axelsson, Emil K; Liethof, Lisanne et al.

Ingår i Journal of Sleep Research, s. 5-10, 2016

• DOI för A single night of partial sleep loss impairs fasting insulin sensitivity but does not affect cephalic phase insulin release in young men
• Ladda ner fulltext (pdf) av A single night of partial sleep loss impairs fasting insulin sensitivity but does not affect cephalic phase insulin release in young men

Oxytocin Acting in the Nucleus Accumbens Core Decreases Food Intake

Herisson, F. M.; Waas, J. R.; Fredriksson, Robert; Schiöth, Helgi B. et al.

Ingår i Journal of neuroendocrinology, 2016

• DOI för Oxytocin Acting in the Nucleus Accumbens Core Decreases Food Intake

The Drosophila ETV5 homologue Ets96B: Molecular link between obesity and bipolar disorder

Williams, Michael; Klockars, Anica; Eriksson, Anders; Voisin, Sarah et al.

Ingår i PLOS Genetics, 2016

• DOI för The Drosophila ETV5 homologue Ets96B: Molecular link between obesity and bipolar disorder
• Ladda ner fulltext (pdf) av The Drosophila ETV5 homologue Ets96B: Molecular link between obesity and bipolar disorder

Bis-(2-ethylhexyl) Phthalate Increases Insulin Expression and Lipid Levels in Drosophila melanogaster

Cao, Hao; Wiemerslage, Lyle; Marttila, Petra S. K.; Williams, Michael J. et al.

Ingår i Basic & Clinical Pharmacology & Toxicology, s. 309-316, 2016

• DOI för Bis-(2-ethylhexyl) Phthalate Increases Insulin Expression and Lipid Levels in Drosophila melanogaster

A new, simple and robust radioligand binding method used to determine kinetic off-rate constants for unlabeled ligands. Application at alpha(2A)- and alpha(2C)-adrenoceptors

Uhlén, Staffan; Schiöth, Helgi B.; Jahnsen, Jan Anker

Ingår i European Journal of Pharmacology, s. 113-121, 2016

• DOI för A new, simple and robust radioligand binding method used to determine kinetic off-rate constants for unlabeled ligands. Application at alpha(2A)- and alpha(2C)-adrenoceptors
• Ladda ner fulltext (pdf) av A new, simple and robust radioligand binding method used to determine kinetic off-rate constants for unlabeled ligands. Application at alpha(2A)- and alpha(2C)-adrenoceptors

Chenodeoxycholic acid significantly impacts the expression of miRNAs and genes involved in lipid, bile acid and drug metabolism in human hepatocytes

Krattinger, Regina; Boström, Adrian; Lee, Serene M. L.; Thasler, Wolfgang E. et al.

Ingår i Life Sciences, s. 47-56, 2016

• DOI för Chenodeoxycholic acid significantly impacts the expression of miRNAs and genes involved in lipid, bile acid and drug metabolism in human hepatocytes
• Ladda ner fulltext (pdf) av Chenodeoxycholic acid significantly impacts the expression of miRNAs and genes involved in lipid, bile acid and drug metabolism in human hepatocytes

Reduced vasopressin receptors activation mediates the anti-depressant effects of fluoxetine and venlafaxine in bulbectomy model of depression

Poretti, María Belén; Sawant, Rahul S; Rask-Andersen, Mathias; de Cuneo, Marta Fiol et al.

Ingår i Psychopharmacology, s. 1077-1086, 2016

• DOI för Reduced vasopressin receptors activation mediates the anti-depressant effects of fluoxetine and venlafaxine in bulbectomy model of depression

Sleep restriction alters plasma endocannabinoids concentrations before but not after exercise in humans

Cedernaes, Jonathan; Fanelli, Flaminia; Fazzini, Alessia; Pagotto, Uberto et al.

Ingår i Psychoneuroendocrinology, s. 258-268, 2016

• DOI för Sleep restriction alters plasma endocannabinoids concentrations before but not after exercise in humans
• Ladda ner fulltext (pdf) av Sleep restriction alters plasma endocannabinoids concentrations before but not after exercise in humans

Dibutyl Phthalate Exposure Disrupts Evolutionarily Conserved Insulin and Glucagon-Like Signaling in Drosophila Males

Williams, Michael J.; Wiemerslage, Lyle; Gohel, Priya; Kheder, Sania et al.

Ingår i Endocrinology, s. 2309-2321, 2016

• DOI för Dibutyl Phthalate Exposure Disrupts Evolutionarily Conserved Insulin and Glucagon-Like Signaling in Drosophila Males

The Drosophila ortholog of TMEM18 regulates insulin and glucagon-like signaling

Wiemerslage, Lyle; Gohel, Priya A.; Maestri, Giulia; Hilmarsson, Torfi G. et al.

Ingår i Journal of Endocrinology, s. 233-243, 2016

• DOI för The Drosophila ortholog of TMEM18 regulates insulin and glucagon-like signaling

Association of the LINGO2-related SNP rs10968576 with body mass in a cohort of elderly Swedes

Rask-Andersen, Mathias; Almén, Markus Sällman; Lind, Lars; Schiöth, Helgi B.

Ingår i Molecular Genetics and Genomics, s. 1485-1491, 2015

• DOI för Association of the LINGO2-related SNP rs10968576 with body mass in a cohort of elderly Swedes

Kiwi genome provides insights into evolution of a nocturnal lifestyle

Le Duc, Diana; Renaud, Gabriel; Krishnan, Arunkumar; Almén, Markus Sällman et al.

Ingår i Genome Biology, 2015

• DOI för Kiwi genome provides insights into evolution of a nocturnal lifestyle
• Ladda ner fulltext (pdf) av Kiwi genome provides insights into evolution of a nocturnal lifestyle

Determination of obesity associated gene variants related to TMEM18 through ultra-deep targeted re-sequencing in a case-control cohort for pediatric obesity.

Rask-Andersen, Mathias; Sällman Almén, Markus; Jacobsson, Josefin A; Ameur, Adam et al.

Ingår i Genetical Research, 2015

• DOI för Determination of obesity associated gene variants related to TMEM18 through ultra-deep targeted re-sequencing in a case-control cohort for pediatric obesity.

Dietary fat quality impacts genome-wide DNA methylation patterns in a cross-sectional study of Greek preadolescents

Voisin, Sarah; Almén, Markus S; Moschonis, George; Chrousos, George P et al.

Ingår i European Journal of Human Genetics, s. 654-662, 2015

• DOI för Dietary fat quality impacts genome-wide DNA methylation patterns in a cross-sectional study of Greek preadolescents

Defining the gene repertoire and spatiotemporal expression profiles of adhesion G protein-coupled receptors in zebrafish

Harty, Breanne L.; Krishnan, Arunkumar; Sanchez, Nicholas E.; Schiöth, Helgi B. et al.

Ingår i BMC Genomics, 2015

• DOI för Defining the gene repertoire and spatiotemporal expression profiles of adhesion G protein-coupled receptors in zebrafish
• Ladda ner fulltext (pdf) av Defining the gene repertoire and spatiotemporal expression profiles of adhesion G protein-coupled receptors in zebrafish

Scrutinizing the FTO locus: compelling evidence for a complex, long-range regulatory context

Rask-Andersen, Mathias; Almén, Markus Sallman; Schiöth, Helgi B.

Ingår i Human Genetics, s. 1183-1193, 2015

• DOI för Scrutinizing the FTO locus: compelling evidence for a complex, long-range regulatory context

Roux-En Y Gastric Bypass Surgery Induces Genome-Wide Promoter-Specific Changes in DNA Methylation in Whole Blood of Obese Patients

Nilsson, Emil; Ernst, Barbara; Voisin, Sarah; Sällman Almén, Markus et al.

Ingår i PLOS ONE, 2015

• DOI för Roux-En Y Gastric Bypass Surgery Induces Genome-Wide Promoter-Specific Changes in DNA Methylation in Whole Blood of Obese Patients
• Ladda ner fulltext (pdf) av Roux-En Y Gastric Bypass Surgery Induces Genome-Wide Promoter-Specific Changes in DNA Methylation in Whole Blood of Obese Patients

Many obesity-associated SNPs strongly associate with DNA methylation changes at proximal promoters and enhancers

Voisin, Sarah; Almén, Markus Sällman; Zheleznyakova, Galina Y.; Lundberg, Lina et al.

Ingår i Genome Medicine, 2015

• DOI för Many obesity-associated SNPs strongly associate with DNA methylation changes at proximal promoters and enhancers
• Ladda ner fulltext (pdf) av Many obesity-associated SNPs strongly associate with DNA methylation changes at proximal promoters and enhancers

Implication of coronin 7 in body weight regulation in humans, mice and flies

Eriksson, Anders; Williams, Michael J.; Voisin, Sarah; Hansson, Ida et al.

Ingår i BMC Neuroscience, 2015

• DOI för Implication of coronin 7 in body weight regulation in humans, mice and flies
• Ladda ner fulltext (pdf) av Implication of coronin 7 in body weight regulation in humans, mice and flies

Determinants of Shortened, Disrupted, and Mistimed Sleep and Associated Metabolic Health Consequences in Healthy Humans

Cedernaes, Jonathan; Schiöth, Helgi B.; Benedict, Christian

Ingår i Diabetes, s. 1073-1080, 2015

• DOI för Determinants of Shortened, Disrupted, and Mistimed Sleep and Associated Metabolic Health Consequences in Healthy Humans

The Role of FTO and Vitamin D for the Weight Loss Effect of Roux-en-Y Gastric Bypass Surgery in Obese Patients

Bandstein, Marcus; Schultes, Bernd; Ernst, Barbara; Thurnheer, Martin et al.

Ingår i Obesity Surgery, s. 2071-2077, 2015

• DOI för The Role of FTO and Vitamin D for the Weight Loss Effect of Roux-en-Y Gastric Bypass Surgery in Obese Patients
• Ladda ner fulltext (pdf) av The Role of FTO and Vitamin D for the Weight Loss Effect of Roux-en-Y Gastric Bypass Surgery in Obese Patients

Short Sleep Makes Declarative Memories Vulnerable to Stress in Humans

Cedernaes, Jonathan; Rångtell, Frida H.; Axelsson, Emil K.; Yeganeh, Adine et al.

Ingår i Sleep, s. 1861-1868, 2015

• DOI för Short Sleep Makes Declarative Memories Vulnerable to Stress in Humans

Acute Sleep Loss Induces Tissue-Specific Epigenetic and Transcriptional Alterations to Circadian Clock Genes in Men

Cedernaes, Jonathan; Osler, Megan E.; Voisin, Sarah; Broman, Jan-Erik et al.

Ingår i Journal of Clinical Endocrinology and Metabolism, 2015

• DOI för Acute Sleep Loss Induces Tissue-Specific Epigenetic and Transcriptional Alterations to Circadian Clock Genes in Men

Patients Lacking Sustainable Long-Term Weight Loss after Gastric Bypass Surgery Show Signs of Decreased Inhibitory Control of Prepotent Responses

Hogenkamp, Pleunie S.; Sundbom, Magnus; Nilsson, Victor C.; Benedict, Christian et al.

Ingår i PLOS ONE, 2015

• DOI för Patients Lacking Sustainable Long-Term Weight Loss after Gastric Bypass Surgery Show Signs of Decreased Inhibitory Control of Prepotent Responses
• Ladda ner fulltext (pdf) av Patients Lacking Sustainable Long-Term Weight Loss after Gastric Bypass Surgery Show Signs of Decreased Inhibitory Control of Prepotent Responses

Television Watching and Effects on Food Intake: Distress vs Eustress

Benedict, Christian; Schiöth, Helgi B.; Cedernaes, Jonathan

Ingår i JAMA Internal Medicine, s. 468-468, 2015

Are you sure?: Confidence about the satiating capacity of a food affects subsequent food intake

Schiöth, Helgi; Ferriday, Danielle; Davies, Sarah; Benedict, Christian et al.

Ingår i Nutrients, s. 5088-5097, 2015

• DOI för Are you sure?: Confidence about the satiating capacity of a food affects subsequent food intake
• Ladda ner fulltext (pdf) av Are you sure?: Confidence about the satiating capacity of a food affects subsequent food intake

Associations of self-reported sleep disturbance and duration with academic failure in community-dwelling Swedish adolescents: Sleep and academic performance at school

Titova, Olga E; Hogenkamp, Pleunie S; Jacobsson, Josefin A; Feldman, Inna et al.

Ingår i Sleep Medicine, s. 87-93, 2015

• DOI för Associations of self-reported sleep disturbance and duration with academic failure in community-dwelling Swedish adolescents: Sleep and academic performance at school
• Ladda ner fulltext (pdf) av Associations of self-reported sleep disturbance and duration with academic failure in community-dwelling Swedish adolescents: Sleep and academic performance at school

Self-reported sleep disturbance is associated with Alzheimer's disease risk in men

Benedict, Christian; Byberg, Liisa; Cedernaes, Jonathan; Hogenkamp, Pleunie S et al.

Ingår i Alzheimer's & Dementia, s. 1090-1097, 2015

• DOI för Self-reported sleep disturbance is associated with Alzheimer's disease risk in men
• Ladda ner fulltext (pdf) av Self-reported sleep disturbance is associated with Alzheimer's disease risk in men

The Orphan G Protein-Coupled Receptor Gene GPR178 Is Evolutionary Conserved and Altered in Response to Acute Changes in Food Intake

Caruso, Vanni; Le Greves, Madeleine; Fard, Shahrzad Shirazi; Haitina, Tatjana et al.

Ingår i PLOS ONE, 2015

• DOI för The Orphan G Protein-Coupled Receptor Gene GPR178 Is Evolutionary Conserved and Altered in Response to Acute Changes in Food Intake
• Ladda ner fulltext (pdf) av The Orphan G Protein-Coupled Receptor Gene GPR178 Is Evolutionary Conserved and Altered in Response to Acute Changes in Food Intake

Methylation Levels of SLC23A2 and NCOR2 Genes Correlate with Spinal Muscular Atrophy Severity

Zheleznyakova, Galina Yu; Nilsson, Emil K.; Kiselev, Anton V.; Maretina, Marianna A. et al.

Ingår i PLOS ONE, 2015

• DOI för Methylation Levels of SLC23A2 and NCOR2 Genes Correlate with Spinal Muscular Atrophy Severity
• Ladda ner fulltext (pdf) av Methylation Levels of SLC23A2 and NCOR2 Genes Correlate with Spinal Muscular Atrophy Severity

Ghrelin effects expression of several genes associated with depression-like behavior

Poretti, María Belén; Rask-Andersen, Mathias; Kumar, Praveen; Rubiales de Barioglio, Susana et al.

Ingår i Progress in Neuro-psychopharmacology and Biological Psychiatry, s. 227-234, 2015

• DOI för Ghrelin effects expression of several genes associated with depression-like behavior

Interleukin-1 beta-induced memory reconsolidation impairment is mediated by a reduction in glutamate release and zif268 expression and alpha-melanocyte-stimulating hormone prevented these effects

Machado, Ivana; Gonzalez, Patricia V.; Vilcaes, Alejandro; Carniglia, Lila et al.

Ingår i Brain, behavior, and immunity, s. 137-146, 2015

• DOI för Interleukin-1 beta-induced memory reconsolidation impairment is mediated by a reduction in glutamate release and zif268 expression and alpha-melanocyte-stimulating hormone prevented these effects

Ghrelin increases memory consolidation through hippocampal mechanisms dependent on glutamate release and NR2B-subunits of the NMDA receptor

Ghersi, Marisa S; Gabach, L A; Buteler, F; Vilcaes, A A et al.

Ingår i Psychopharmacology, s. 1843-1857, 2015

• DOI för Ghrelin increases memory consolidation through hippocampal mechanisms dependent on glutamate release and NR2B-subunits of the NMDA receptor

The obesity-linked Nudt3 Drosophila homolog Aps is associated with insulin signalling

Williams, Michael; Eriksson, Anders; Shaik, Muksheed; Voisin, Sarah et al.

Ingår i Molecular Endocrinology, s. 1303-1319, 2015

• DOI för The obesity-linked Nudt3 Drosophila homolog Aps is associated with insulin signalling

MicroRNA-192 regulates the expression of the farnesoid X receptor

Krattinger, Regina; Mwinyi, Jessica; Kullak-Ublick, Gerd A.; Schiöth, Helgi B. et al.

Ingår i Hepatology, 2015

Gabaergic control of anxiety-like behavior, but not food intake, induced by ghrelin in the intermediate medial mesopallium of the neonatal chick

Gaston, M. S.; Schiöth, Helgi B.; De Barioglio, S. R.; Salvatierra, N. A.

Ingår i Hormones and Behavior, s. 66-72, 2015

• DOI för Gabaergic control of anxiety-like behavior, but not food intake, induced by ghrelin in the intermediate medial mesopallium of the neonatal chick

Evolutionary hierarchy of vertebrate-like heterotrimeric G protein families

Krishnan, Arunkumar; Mustafa, Arshi; Almén, Markus Sällman; Fredriksson, Robert et al.

Ingår i Molecular Phylogenetics and Evolution, s. 27-40, 2015

• DOI för Evolutionary hierarchy of vertebrate-like heterotrimeric G protein families

The fat mass and obesity-associated gene (FTO) is linked to higher plasma levels of the hunger hormone ghrelin and lower serum levels of the satiety hormone leptin in older adults

Benedict, Christian; Axelsson, Tomas; Söderberg, Stefan; Larsson, Anders et al.

Ingår i Diabetes, s. 3955-3959, 2014

• DOI för The fat mass and obesity-associated gene (FTO) is linked to higher plasma levels of the hunger hormone ghrelin and lower serum levels of the satiety hormone leptin in older adults

Increased Impulsivity in Response to Food Cues after Sleep Loss in Healthy Young Men

Cedernaes, Jonathan; Brandell, Jon; Ros, Olof; Broman, Jan-Erik et al.

Ingår i Obesity, s. 1786-1791, 2014

• DOI för Increased Impulsivity in Response to Food Cues after Sleep Loss in Healthy Young Men
• Ladda ner fulltext (pdf) av Increased Impulsivity in Response to Food Cues after Sleep Loss in Healthy Young Men

The GPCR repertoire in the demosponge Amphimedon queenslandica: insights into the GPCR system at the early divergence of animals

Krishnan, Arunkumar; Dnyansagar, Rohit; Almén, Markus Sällman; Williams, Michael J. et al.

Ingår i BMC Evolutionary Biology, 2014

• DOI för The GPCR repertoire in the demosponge Amphimedon queenslandica: insights into the GPCR system at the early divergence of animals
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Long-term oral melatonin administration reduces ethanol-induced increases in duodenal mucosal permeability and motility in rats

Sommansson, Anna; Yamskova, Olga; Schiöth, Helgi B.; Nylander, Olof et al.

Ingår i Acta Physiologica, s. 152-165, 2014

• DOI för Long-term oral melatonin administration reduces ethanol-induced increases in duodenal mucosal permeability and motility in rats

Genome-wide analysis reveals DNA methylation markers that vary with both age and obesity

Almén, Markus Sällman; Nilsson, Emil K.; Jacobsson, Josefin A.; Kalnina, Ineta et al.

Ingår i Gene, s. 61-67, 2014

• DOI för Genome-wide analysis reveals DNA methylation markers that vary with both age and obesity
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Watching TV and Food Intake: The Role of Content

Chapman, Colin D.; Nilsson, Victor C.; Thune, Hanna A.; Cedernaes, Jonathan et al.

Ingår i PLOS ONE, 2014

• DOI för Watching TV and Food Intake: The Role of Content
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Acute sleep deprivation in healthy young men: Impact on population diversity and function of circulating neutrophils

Christoffersson, Gustaf; Vågesjö, Evelina; Pettersson, Ulrika S.; Massena, Sara et al.

Ingår i Brain, behavior, and immunity, s. 162-172, 2014

• DOI för Acute sleep deprivation in healthy young men: Impact on population diversity and function of circulating neutrophils

Efficacy of antibody-based therapies to treat Alzheimer's disease: Just a matter of timing?

Cedernaes, Jonathan; Schiöth, Helgi B.; Benedict, Christian

Ingår i Experimental Gerontology, s. 104-106, 2014

• DOI för Efficacy of antibody-based therapies to treat Alzheimer's disease: Just a matter of timing?

Acute sleep deprivation increases serum levels of neuron-specific enolase (NSE) and S100 calcium binding protein B (S-100B) in healthy young men

Benedict, Christian; Cedernaes, Jonathan; Giedraitis, Vilmantas; Nilsson, Emil K et al.

Ingår i Sleep, s. 195-198, 2014

• DOI för Acute sleep deprivation increases serum levels of neuron-specific enolase (NSE) and S100 calcium binding protein B (S-100B) in healthy young men

Late-life alcohol consumption and cognitive function in elderly men

Hogenkamp, Pleunie S.; Benedict, Christian; Sjögren, Per; Kilander, Lena et al.

Ingår i Age (Omaha), s. 243-249, 2014

• DOI för Late-life alcohol consumption and cognitive function in elderly men

Obesity-linked homologues TfAP-2 and Twz establish meal frequency in Drosophila melanogaster

Williams, Michael; Goergen, Philip; Rajendran, Jayasimman; Zheleznyakova, Galina et al.

Ingår i PLOS Genetics, 2014

• DOI för Obesity-linked homologues TfAP-2 and Twz establish meal frequency in Drosophila melanogaster
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Obsessive-compulsivity and working memory are associated with differential prefrontal cortex and insula activation in adolescents with a recent diagnosis of an eating disorder

Brooks, Samantha J; Solstrand Dahlberg, Linda; Swenne, Ingemar; Aronsson, Marianne et al.

Ingår i Psychiatry Research, s. 246-253, 2014

• DOI för Obsessive-compulsivity and working memory are associated with differential prefrontal cortex and insula activation in adolescents with a recent diagnosis of an eating disorder

The G protein-coupled receptor GPR162 is widely distributed in the CNS and highly expressed in the hypothalamus and in hedonic feeding areas

Caruso, Vanni; Hägglund, Maria G.; Badiali, Luca; Bagchi, Sonchita et al.

Ingår i Gene, s. 1-6, 2014

• DOI för The G protein-coupled receptor GPR162 is widely distributed in the CNS and highly expressed in the hypothalamus and in hedonic feeding areas

Exposure to a high-fat high-sugar diet causes strong up-regulation of proopiomelanocortin and differentially affects dopamine D1 and D2 receptor gene expression in the brainstem of rats

Alsiö, Johan; Rask-Andersen, Mathias; Chavan, Rohit A.; Olszewski, Pawel K. et al.

Ingår i Neuroscience Letters, s. 18-23, 2014

• DOI för Exposure to a high-fat high-sugar diet causes strong up-regulation of proopiomelanocortin and differentially affects dopamine D1 and D2 receptor gene expression in the brainstem of rats

BDNF polymorphisms are linked to poorer working memory performance, reduced cerebellar and hippocampal volumes and differences in prefrontal cortex in a Swedish elderly population

Brooks, Samantha J; Nilsson, Emil K; Jacobsson, Josefin A; Stein, Dan J et al.

Ingår i PLOS ONE, 2014

• DOI för BDNF polymorphisms are linked to poorer working memory performance, reduced cerebellar and hippocampal volumes and differences in prefrontal cortex in a Swedish elderly population
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CDKAL1-Related Single Nucleotide Polymorphisms Are Associated with Insulin Resistance in a Cross-Sectional Cohort of Greek Children

Rask-Andersen, Mathias; Philippot, Gaetan; Moschonis, George; Dedoussis, George et al.

Ingår i PLOS ONE, 2014

• DOI för CDKAL1-Related Single Nucleotide Polymorphisms Are Associated with Insulin Resistance in a Cross-Sectional Cohort of Greek Children
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Insights into the Origin of Nematode Chemosensory GPCRs: Putative Orthologs of the Srw Family Are Found across Several Phyla of Protostomes

Krishnan, Arunkumar; Almén, Markus Sällman; Fredriksson, Robert; Schiöth, Helgi B.

Ingår i PLOS ONE, 2014

• DOI för Insights into the Origin of Nematode Chemosensory GPCRs: Putative Orthologs of the Srw Family Are Found across Several Phyla of Protostomes
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The Drosophila Kctd-family homologue Kctd12-like modulates male aggression and mating behaviour

Williams, Michael J.; Goergen, Philip; Phad, Ganesh; Fredriksson, Robert et al.

Ingår i European Journal of Neuroscience, s. 2513-2526, 2014

• DOI för The Drosophila Kctd-family homologue Kctd12-like modulates male aggression and mating behaviour

New functions and signaling mechanisms for the class of adhesion G protein-coupled receptors

Liebscher, Ines; Ackley, Brian; Araç, Demet; Ariestanti, Donna M et al.

Ingår i Annals of the New York Academy of Sciences, s. 43-64, 2014

• DOI för New functions and signaling mechanisms for the class of adhesion G protein-coupled receptors

Subliminal versus supraliminal stimuli activate neural responses in anterior cingulate cortex, fusiform gyrus and insula: a meta-analysis of fMRI studies

Meneguzzo, Paolo; Tsakiris, Manos; Schiöth, Helgi B.; Stein, Dan J et al.

Ingår i BMC Psychology, 2014

• DOI för Subliminal versus supraliminal stimuli activate neural responses in anterior cingulate cortex, fusiform gyrus and insula: a meta-analysis of fMRI studies

The role of common and rare MC4R variants and FTO polymorphisms in extreme form of obesity

Rovite, Vita; Petrovska, Ramona; Vaivade, Iveta; Kalnina, Ineta et al.

Ingår i Molecular Biology Reports, s. 1491-500, 2014

• DOI för The role of common and rare MC4R variants and FTO polymorphisms in extreme form of obesity

The Drosophila Small GTPase Rac2 is Required for Normal Feeding and Mating Behaviour.

Goergen, Philip; Kasagiannis, Anna; Schiöth, Helgi B; Williams, Michael J

Ingår i Behavior Genetics, s. 155-64, 2014

• DOI för The Drosophila Small GTPase Rac2 is Required for Normal Feeding and Mating Behaviour.

Regulation of aggression by obesity-linked genes TfAP-2 and Twz through octopamine signaling in Drosophila

Williams, Michael J; Goergen, Philip; Rajendran, Jayasimman; Klockars, Anica et al.

Ingår i Genetics, s. 349-362, 2014

• DOI för Regulation of aggression by obesity-linked genes TfAP-2 and Twz through octopamine signaling in Drosophila

Melanocortin 4 receptor activation inhibits presynaptic N-type calcium channels in amygdaloid complex neurons

Agosti, Francina; Lopez Soto, Eduardo J.; Cabral, Agustina; Castrogiovanni, Daniel et al.

Ingår i European Journal of Neuroscience, s. 2755-2765, 2014

• DOI för Melanocortin 4 receptor activation inhibits presynaptic N-type calcium channels in amygdaloid complex neurons

Replacement of short segments within transmembrane domains of MC2R disrupts retention signal

Fridmanis, Davids; Petrovska, Ramona; Pjanova, Dace; Schiöth, Helgi B. et al.

Ingår i Journal of Molecular Endocrinology, s. 201-215, 2014

• DOI för Replacement of short segments within transmembrane domains of MC2R disrupts retention signal

The druggable genome: Evaluation of drug targets in clinical trials suggests major shifts in molecular class and indication

Rask-Andersen, Mathias; Masuram, Surendar; Schiöth, Helgi B

Ingår i Annual Review of Pharmacology and Toxicology, s. 9-26, 2014

• DOI för The druggable genome: Evaluation of drug targets in clinical trials suggests major shifts in molecular class and indication

Exposure to Bisphenol A Affects Lipid Metabolism in Drosophila melanogaster

Williams, Michael J; Wang, Yi; Klockars, Anica; Lind, Monica et al.

Ingår i Basic & Clinical Pharmacology & Toxicology, s. 414-420, 2014

• DOI för Exposure to Bisphenol A Affects Lipid Metabolism in Drosophila melanogaster

Calorie anticipation alters food intake after low-caloric but not high-caloric preloads

Hogenkamp, Pleunie; Cedernaes, Jonathan; Chapman, Colin; Vogel, Heike et al.

Ingår i Obesity, s. 1548-1553, 2013

• DOI för Calorie anticipation alters food intake after low-caloric but not high-caloric preloads
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Adipose tissue stearoyl-CoA desaturase 1 index is increased and linoleic acid is decreased in obesity-prone rats fed a high-fat diet

Cedernaes, Jonathan; Alsiö, Johan; Västermark, Åke; Risérus, Ulf et al.

Ingår i Lipids in Health and Disease, 2013

• DOI för Adipose tissue stearoyl-CoA desaturase 1 index is increased and linoleic acid is decreased in obesity-prone rats fed a high-fat diet

Anorexia nervosa is linked to reduced brain structure in reward and somatosensory regions: a meta-analysis of VBM studies

Titova, Olga E; Hjorth, Olof C; Schiöth, Helgi B.; Brooks, Samantha J

Ingår i BMC Psychiatry, s. 110, 2013

• DOI för Anorexia nervosa is linked to reduced brain structure in reward and somatosensory regions: a meta-analysis of VBM studies
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Characterization of the transporterB⁰AT3 (Slc6a17) in the rodent central nervous system

Hägglund, Maria G. A.; Hellsten, Sofie V.; Bagchi, Sonchita; Ljungdahl, Anna et al.

Ingår i BMC Neuroscience, s. 54, 2013

• DOI för Characterization of the transporterB⁰AT3 (Slc6a17) in the rodent central nervous system
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Dietary intake of eicosapentaenoic and docosahexaenoic acids is linked to gray matter volume and cognitive function in elderly

Titova, Olga E; Sjögren, Per; Brooks, Samantha J; Kullberg, Joel et al.

Ingår i Age (Omaha), s. 1495-1505, 2013

• DOI för Dietary intake of eicosapentaenoic and docosahexaenoic acids is linked to gray matter volume and cognitive function in elderly

Mediterranean diet habits in older individuals: Associations with cognitive functioning and brain volumes

Titova, Olga E; Ax, Erika; Brooks, Samantha J; Sjögren, Per et al.

Ingår i Experimental Gerontology, s. 1443-1448, 2013

• DOI för Mediterranean diet habits in older individuals: Associations with cognitive functioning and brain volumes

Association between physical activity and brain health in older adults

Benedict, Christian; Brooks, Samantha J; Kullberg, Joel; Nordenskjöld, Richard et al.

Ingår i Neurobiology of Aging, s. 83-90, 2013

• DOI för Association between physical activity and brain health in older adults

Acute sleep deprivation increases portion size and affects food choice in young men

Hogenkamp, Pleunie S; Nilsson, Emil; Nilsson, Victor C; Chapman, Colin D et al.

Ingår i Psychoneuroendocrinology, s. 1668-1674, 2013

• DOI för Acute sleep deprivation increases portion size and affects food choice in young men

Acute sleep deprivation increases food purchasing in men

Chapman, Colin D.; Nilsson, Emil K.; Nilsson, Victor C.; Cedernaes, Jonathan et al.

Ingår i Obesity, 2013

• DOI för Acute sleep deprivation increases food purchasing in men

Growth Hormone-Releasing Hormone Improves Cognitive Function in Older Adults: Sleep On It

Benedict, Christian; Chapman, Colin D; Schiöth, Helgi B

Ingår i JAMA neurology, s. 529-530, 2013

• DOI för Growth Hormone-Releasing Hormone Improves Cognitive Function in Older Adults: Sleep On It

Late-life obesity is associated with smaller global and regional gray matter volumes: a voxel-based morphometric study

Brooks, Samantha J; Benedict, Christian; Burgos, J; Kempton, M J et al.

Ingår i International Journal of Obesity, s. 230-236, 2013

• DOI för Late-life obesity is associated with smaller global and regional gray matter volumes: a voxel-based morphometric study

Sweet taste perception not altered after acute sleep deprivation in healthy young men

Hogenkamp, Pleunie S; Nilsson, Emil; Chapman, C D; Cedernaes, Jonathan et al.

Ingår i Somnologie, s. 111-114, 2013

• DOI för Sweet taste perception not altered after acute sleep deprivation in healthy young men

Involvement of the Neutral Amino Acid Transporter SLC6A15 and Leucine in Obesity-Related Phenotypes

Drgonova, Jana; Jacobsson, Josefin A.; Han, Joan C.; Yanovski, Jack A. et al.

Ingår i PLOS ONE, 2013

• DOI för Involvement of the Neutral Amino Acid Transporter SLC6A15 and Leucine in Obesity-Related Phenotypes
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Genome-wide analysis shows association of epigenetic changes in regulators of Rab and Rho GTPases with spinal muscular atrophy severity

Zheleznyakova, Galina Y.; Voisin, Sarah; Kiselev, Anton V.; Almén, Markus Sällman et al.

Ingår i European Journal of Human Genetics, s. 988-993, 2013

• DOI för Genome-wide analysis shows association of epigenetic changes in regulators of Rab and Rho GTPases with spinal muscular atrophy severity

Increased prefrontal and parahippocampal activation with reduced dorsolateral prefrontal and insular cortex activation to food images in obesity: a meta-analysis of fMRI studies.

Brooks, Samantha J; Cedernaes, Jonathan; Schiöth, Helgi B

Ingår i PLOS ONE, 2013

• DOI för Increased prefrontal and parahippocampal activation with reduced dorsolateral prefrontal and insular cortex activation to food images in obesity: a meta-analysis of fMRI studies.
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B(0)AT2 (SLC6A15) is localized to neurons and astrocytes, and is involved in mediating the effect of leucine in the brain

Hägglund, Maria G A; Roshanbin, Sahar; Löfqvist, Erik; Hellsten, Sofie V et al.

Ingår i PLOS ONE, 2013

• DOI för B(0)AT2 (SLC6A15) is localized to neurons and astrocytes, and is involved in mediating the effect of leucine in the brain
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The STK33-linked SNP rs4929949 is associated with obesity and BMI in two independent cohorts of Swedish and Greek children

Rask-Andersen, Mathias; Moschonis, George; Chrousos, George; Marcus, Claude et al.

Ingår i PLOS ONE, 2013

• DOI för The STK33-linked SNP rs4929949 is associated with obesity and BMI in two independent cohorts of Swedish and Greek children
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Effect of oral processing behaviour on food intake and satiety

Hogenkamp, Pleunie S.; Schiöth, Helgi B.

Ingår i Trends in Food Science & Technology, s. 67-75, 2013

• DOI för Effect of oral processing behaviour on food intake and satiety

Polymorphisms in FTO and near TMEM18 associate with type 2 diabetes and predispose to younger age at diagnosis of diabetes

Kalnina, Ineta; Zaharenko, Linda; Vaivade, Iveta; Rovite, Vita et al.

Ingår i Gene, s. 462-468, 2013

• DOI för Polymorphisms in FTO and near TMEM18 associate with type 2 diabetes and predispose to younger age at diagnosis of diabetes

Remarkable similarities between the hemichordate (Saccoglossus kowalevskii) and vertebrate GPCR repertoire

Krishnan, Arunkumar; Almén, Markus Sällman; Fredriksson, Robert; Schiöth, Helgi B.

Ingår i Gene, s. 122-133, 2013

• DOI för Remarkable similarities between the hemichordate (Saccoglossus kowalevskii) and vertebrate GPCR repertoire

Early vertebrate origin of melanocortin 2 receptor accessory proteins (MRAPs)

Valsalan, Ravisankar; Krishnan, Arunkumar; Almén, Markus Sällman; Fredriksson, Robert et al.

Ingår i General and Comparative Endocrinology, s. 123-132, 2013

• DOI för Early vertebrate origin of melanocortin 2 receptor accessory proteins (MRAPs)

Determination of the obesity-associated gene variants within the entire FTO gene by ultra-deep targeted sequencing in obese and lean children.

Sällman Almén, Markus; Rask-Andersen, Mathias; Jacobsson, Josefin A; Ameur, Adam et al.

Ingår i International Journal of Obesity, s. 424-431, 2013

• DOI för Determination of the obesity-associated gene variants within the entire FTO gene by ultra-deep targeted sequencing in obese and lean children.

Molecular mechanisms involved in interleukin 1-beta (IL-1 beta)-induced memory impairment. Modulation by alpha-melanocyte-stimulating hormone (alpha-MSH)

Gonzalez, P.; Machado, I.; Vilcaes, A.; Caruso, C. et al.

Ingår i Brain, behavior, and immunity, s. 141-150, 2013

• DOI för Molecular mechanisms involved in interleukin 1-beta (IL-1 beta)-induced memory impairment. Modulation by alpha-melanocyte-stimulating hormone (alpha-MSH)

Insulin receptor-like ectodomain genes and splice variants are found in both arthropods and human brain cDNA

Vastermark, Åke; Rask-Andersen, Mathias; Sawant, Rahul S.; Reiter, Jill L. et al.

Ingår i Journal of Systematics and Evolution, s. 664-670, 2013

• DOI för Insulin receptor-like ectodomain genes and splice variants are found in both arthropods and human brain cDNA

Adhesion GPCRs are widely expressed throughout the subsections of the gastrointestinal tract

Badiali, Luca; Cedernaes, Jonathan; Olszewski, Pawel K; Nylander, Olof et al.

Ingår i BMC Gastroenterology, s. 134, 2012

• DOI för Adhesion GPCRs are widely expressed throughout the subsections of the gastrointestinal tract
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A debate on current eating disorder diagnoses in light of neurobiological findings: is it time for a spectrum model?

Brooks, Samantha Jane; Rask-Andersen, Mathias; Benedict, Christian; Schiöth, Helgi Birgir

Ingår i BMC Psychiatry, s. 76, 2012

• DOI för A debate on current eating disorder diagnoses in light of neurobiological findings: is it time for a spectrum model?
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The MAP2K5-linked SNP rs2241423 is associated with BMI and obesity in two cohorts of Swedish and Greek children

Rask-Andersen, Mathias; Jacobsson, Josefin A.; Moschonis, George; Ek, Anna E. et al.

Ingår i BMC Medical Genetics, s. 36, 2012

• DOI för The MAP2K5-linked SNP rs2241423 is associated with BMI and obesity in two cohorts of Swedish and Greek children
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Acute sleep deprivation has no lasting effects on the human antibody titer response following a novel influenza A H1N1 virus vaccination

Benedict, Christian; Brytting, Maria; Markström, Agneta; Broman, Jan-Erik et al.

Ingår i BMC Immunology, s. 1, 2012

• DOI för Acute sleep deprivation has no lasting effects on the human antibody titer response following a novel influenza A H1N1 virus vaccination
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Lifestyle determinants of the drive to eat: a meta-analysis

Chapman, Colin Daniel; Benedict, Christian; Brooks, Samantha Jane; Schiöth, Helgi Birgir

Ingår i American Journal of Clinical Nutrition, s. 492-497, 2012

• DOI för Lifestyle determinants of the drive to eat: a meta-analysis

Brain Insulin Signaling and Alzheimer's Disease: Current Evidence and Future Directions

Schiöth, Helgi B.; Craft, Suzanne; Brooks, Samantha J.; Frey, William H. et al.

Ingår i Molecular Neurobiology, s. 4-10, 2012

• DOI för Brain Insulin Signaling and Alzheimer's Disease: Current Evidence and Future Directions

The influence of active and passive smoking during pregnancy on umbilical cord blood levels of vitamins A and E and neonatal anthropometric indices

Titova, Olga E.; Ayvazova, Elena A.; Bichkaeva, Fatima A.; Brooks, Samantha J. et al.

Ingår i British Journal of Nutrition, s. 1341-1345, 2012

• DOI för The influence of active and passive smoking during pregnancy on umbilical cord blood levels of vitamins A and E and neonatal anthropometric indices

To Sleep or Not To Sleep: Do We Forget Our Patient's Sleep?

Schiöth, Helgi Birgir; Chapman, Colin Daniel; Benedict, Christian

Ingår i Archives of Internal Medicine, s. 746-746, 2012

• DOI för To Sleep or Not To Sleep: Do We Forget Our Patient's Sleep?

Healthcare systems never sleep: are medical residents today the patients of tomorrow?

Schiöth, Helgi Birgir; Brooks, Samantha Jane; Benedict, Christian

Ingår i Sleep Medicine, s. 965-965, 2012

• DOI för Healthcare systems never sleep: are medical residents today the patients of tomorrow?

Impaired Insulin Sensitivity as Indexed by the HOMA Score Is Associated With Deficits in Verbal Fluency and Temporal Lobe Gray Matter Volume in the Elderly

Benedict, Christian; Brooks, Samantha J; Kullberg, Joel; Burgos, Jonathan et al.

Ingår i Diabetes Care, s. 488-494, 2012

• DOI för Impaired Insulin Sensitivity as Indexed by the HOMA Score Is Associated With Deficits in Verbal Fluency and Temporal Lobe Gray Matter Volume in the Elderly

Diurnal Rhythm of Circulating Nicotinamide Phosphoribosyltransferase (Nampt/Visfatin/PBEF): Impact of Sleep Loss and Relation to Glucose Metabolism

Benedict, Christian; Shostak, Anton; Lange, Tanja; Brooks, Samantha J et al.

Ingår i Journal of Clinical Endocrinology and Metabolism, 2012

• DOI för Diurnal Rhythm of Circulating Nicotinamide Phosphoribosyltransferase (Nampt/Visfatin/PBEF): Impact of Sleep Loss and Relation to Glucose Metabolism

Acute Sleep Deprivation Enhances the Brain's Response to Hedonic Food Stimuli: An fMRI Study

Benedict, Christian; Brooks, Samantha J; O'Daly, Owen G; Almèn, Markus S et al.

Ingår i Journal of Clinical Endocrinology and Metabolism, 2012

• DOI för Acute Sleep Deprivation Enhances the Brain's Response to Hedonic Food Stimuli: An fMRI Study

Genome wide analysis reveals association of a FTO gene variant with epigenetic changes

Almén, Markus Sällman; Jacobsson, Josefin A.; Moschonis, George; Benedict, Christian et al.

Ingår i Genomics, s. 132-137, 2012

• DOI för Genome wide analysis reveals association of a FTO gene variant with epigenetic changes

Association of TMEM18 variants with BMI and waist circumference in children and correlation of mRNA expression in the PFC with body weight in rats

Rask-Andersen, Mathias; Jacobsson, Josefin A.; Moschonis, George; Chavan, Rohit A. et al.

Ingår i European Journal of Human Genetics, s. 192-197, 2012

• DOI för Association of TMEM18 variants with BMI and waist circumference in children and correlation of mRNA expression in the PFC with body weight in rats

Neurobeachin, a Regulator of Synaptic Protein Targeting, Is Associated with Body Fat Mass and Feeding Behavior in Mice and Body-Mass Index in Humans

Olszewski, Pawel K.; Rozman, Jan; Jacobsson, Josefin A.; Rathkolb, Birgit et al.

Ingår i PLoS Genetics, 2012

• DOI för Neurobeachin, a Regulator of Synaptic Protein Targeting, Is Associated with Body Fat Mass and Feeding Behavior in Mice and Body-Mass Index in Humans
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The Origin of GPCRs: Identification of Mammalian like Rhodopsin, Adhesion, Glutamate and Frizzled GPCRs in Fungi

Krishnan, Arunkumar; Sällaman Almén, Markus; Fredriksson, Robert; Schiöth, Helgi B

Ingår i PLOS ONE, 2012

• DOI för The Origin of GPCRs: Identification of Mammalian like Rhodopsin, Adhesion, Glutamate and Frizzled GPCRs in Fungi
• Ladda ner fulltext (pdf) av The Origin of GPCRs: Identification of Mammalian like Rhodopsin, Adhesion, Glutamate and Frizzled GPCRs in Fungi

The Dispanins: A Novel Gene Family of Ancient Origin That Contains 14 Human Members

Sällman Almén, Markus; Bringeland, Nathalie; Fredriksson, Robert; Schiöth, Helgi B.

Ingår i PLOS ONE, 2012

• DOI för The Dispanins: A Novel Gene Family of Ancient Origin That Contains 14 Human Members
• Ladda ner fulltext (pdf) av The Dispanins: A Novel Gene Family of Ancient Origin That Contains 14 Human Members

Thinking about Eating Food Activates Visual Cortex with Reduced Bilateral Cerebellar Activation in Females with Anorexia Nervosa: An fMRI Study

Brooks, Samantha J.; O'Daly, Owen; Uher, Rudolf; Friederich, Hans-Christoph et al.

Ingår i PLOS ONE, 2012

• DOI för Thinking about Eating Food Activates Visual Cortex with Reduced Bilateral Cerebellar Activation in Females with Anorexia Nervosa: An fMRI Study
• Ladda ner fulltext (pdf) av Thinking about Eating Food Activates Visual Cortex with Reduced Bilateral Cerebellar Activation in Females with Anorexia Nervosa: An fMRI Study

Identification of Distant Agouti-Like Sequences and Re-Evaluation of the Evolutionary History of the Agouti-Related Peptide (AgRP)

Västermark, Åke; Krishnan, Arunkumar; Houle, Michael E.; Fredriksson, Robert et al.

Ingår i PLOS ONE, 2012

• DOI för Identification of Distant Agouti-Like Sequences and Re-Evaluation of the Evolutionary History of the Agouti-Related Peptide (AgRP)
• Ladda ner fulltext (pdf) av Identification of Distant Agouti-Like Sequences and Re-Evaluation of the Evolutionary History of the Agouti-Related Peptide (AgRP)

Polymorphisms in sh2b1 and spns1 loci are associated with triglyceride levels in a healthy population in northern Sweden

Västermark, Åke; Jacobsson, Josefin; Johansson, Åsa; Fredriksson, Robert et al.

Ingår i Journal of Genetics, s. 237-240, 2012

• DOI för Polymorphisms in sh2b1 and spns1 loci are associated with triglyceride levels in a healthy population in northern Sweden

Genetic variants near the MGAT1 gene are associated with body weight, BMI and fatty acid metabolism among adults and children

Jacobsson, Josefin; Rask-Andersen, Mathias; Risérus, Ulf; Moschonis, G et al.

Ingår i International Journal of Obesity, s. 119-129, 2012

• DOI för Genetic variants near the MGAT1 gene are associated with body weight, BMI and fatty acid metabolism among adults and children

Identification and analysis of functionally important amino acids in human purinergic 12 receptor using a Saccharomyces cerevisiae expression system

Ignatovica, Vita; Megnis, Kaspars; Lapins, Maris; Schiöth, Helgi B et al.

Ingår i The FEBS Journal, s. 180-191, 2012

• DOI för Identification and analysis of functionally important amino acids in human purinergic 12 receptor using a Saccharomyces cerevisiae expression system

Differential effects of fluoxetine and venlafaxine on memory recognition: Possible mechanisms of action

Paola Carlini, Valeria; Belen Poretti, Maria; Rask-Andersen, Mathias; Chavan, Rohit A. et al.

Ingår i Progress in Neuro-psychopharmacology and Biological Psychiatry, s. 159-167, 2012

• DOI för Differential effects of fluoxetine and venlafaxine on memory recognition: Possible mechanisms of action

Acute ghrelin administration reverses depressive-like behavior induced by bilateral olfactory bulbectomy in mice

Paola Carlini, Valeria; Machado, Daniele Guilhermano; Buteler, Florencia; Ghersi, Marisa et al.

Ingår i Peptides, s. 160-165, 2012

• DOI för Acute ghrelin administration reverses depressive-like behavior induced by bilateral olfactory bulbectomy in mice

Subliminal food images compromise superior working memory performance in women with restricting anorexia nervosa

Brooks, Samantha J.; O'Daly, Owen G.; Uher, Rudolf; Schiöth, Helgi B. et al.

Ingår i Consciousness and Cognition, s. 751-763, 2012

• DOI för Subliminal food images compromise superior working memory performance in women with restricting anorexia nervosa

Expression levels of genes encoding melanin concentrating hormone (MCH) and MCH receptor change in taste aversion, but MCH injections do not alleviate aversive responses

Mitra, Anaya; Klockars, Anica; Gosnell, Blake A.; Le Grevés, Madeleine et al.

Ingår i Pharmacology, Biochemistry and Behavior, s. 581-586, 2012

• DOI för Expression levels of genes encoding melanin concentrating hormone (MCH) and MCH receptor change in taste aversion, but MCH injections do not alleviate aversive responses

Single nucleotide polymorphisms of the purinergic 1 receptor are not associated with myocardial infarction in a Latvian population

Ignatovica, Vita; Latkovskis, Gustavs; Peculis, Raitis; Megnis, Kaspars et al.

Ingår i Molecular Biology Reports, s. 1917-1925, 2012

• DOI för Single nucleotide polymorphisms of the purinergic 1 receptor are not associated with myocardial infarction in a Latvian population

Dissecting signaling and functions of adhesion G protein-coupled receptors

Araç, Demet; Aust, Gabriela; Calebiro, Davide; Engel, Felix B et al.

Ingår i Annals of the New York Academy of Sciences, s. 1-25, 2012

• DOI för Dissecting signaling and functions of adhesion G protein-coupled receptors

Functional specialization in nucleotide sugar transporters occurred through differentiation of the gene cluster EamA (DUF6) before the radiation of Viridiplantae

Västermark, Åke; Almén, Markus Sällman; Simmen, Martin W.; Fredriksson, Robert et al.

Ingår i BMC Evolutionary Biology, s. 123, 2011

• DOI för Functional specialization in nucleotide sugar transporters occurred through differentiation of the gene cluster EamA (DUF6) before the radiation of Viridiplantae

Restraint of appetite and reduced regional brain volumes in anorexia nervosa: a voxel-based morphometric study

Brooks, Samantha J; Barker, Gareth J; O'Daly, Owen G; Brammer, Michael et al.

Ingår i BMC Psychiatry, s. 179, 2011

• DOI för Restraint of appetite and reduced regional brain volumes in anorexia nervosa: a voxel-based morphometric study
• Ladda ner fulltext (pdf) av Restraint of appetite and reduced regional brain volumes in anorexia nervosa: a voxel-based morphometric study

Functional coupling analysis suggests link between the obesity gene FTO and the BDNF-NTRK2 signaling pathway

Rask-Andersen, Mathias; Sällman Almén, Markus; Olausen, Hans R.; Olszewski, Pawel K. et al.

Ingår i BMC Neuroscience, s. 117, 2011

• DOI för Functional coupling analysis suggests link between the obesity gene FTO and the BDNF-NTRK2 signaling pathway
• Ladda ner fulltext (pdf) av Functional coupling analysis suggests link between the obesity gene FTO and the BDNF-NTRK2 signaling pathway

Genetic and expression studies of SMN2 gene in Russian patients with spinal muscular atrophy type II and III

Zheleznyakova, Galina Yu; Kiselev, Anton V.; Vakharlovsky, Viktor G.; Rask-Andersen, Mathias et al.

Ingår i BMC Medical Genetics, s. 96, 2011

• DOI för Genetic and expression studies of SMN2 gene in Russian patients with spinal muscular atrophy type II and III

Intranasal Insulin Enhances Postprandial Thermogenesis and Lowers Postprandial Serum Insulin Levels in Healthy Men

Benedict, Christian; Brede, Swantje; Schiöth, Helgi; Lehnert, Hendrik et al.

Ingår i Diabetes, s. 114-118, 2011

• DOI för Intranasal Insulin Enhances Postprandial Thermogenesis and Lowers Postprandial Serum Insulin Levels in Healthy Men

The fat mass and obesity gene is linked to reduced verbal fluency in overweight and obese elderly men

Benedict, Christian; Jacobsson, Josefin A; Rönnemaa, Elina; Sällman Almén, Markus et al.

Ingår i Neurobiology of Aging, s. 11590-115900000, 2011

• DOI för The fat mass and obesity gene is linked to reduced verbal fluency in overweight and obese elderly men

Acute sleep deprivation reduces energy expenditure in healthy men

Benedict, Christian; Hallschmid, Manfred; Lassen, Arne; Mahnke, Christin et al.

Ingår i American Journal of Clinical Nutrition, s. 1229-1236, 2011

• DOI för Acute sleep deprivation reduces energy expenditure in healthy men

Detailed Analysis of Variants in FTO in Association with Body Composition in a Cohort of 70-Year-Olds Suggests a Weakened Effect among Elderly

Jacobsson, Josefin A.; Sällman Almén, Markus; Benedict, Christian; Hedberg, Lilia A. et al.

Ingår i PLOS ONE, 2011

• DOI för Detailed Analysis of Variants in FTO in Association with Body Composition in a Cohort of 70-Year-Olds Suggests a Weakened Effect among Elderly

Intranasal insulin as a therapeutic option in the treatment of cognitive impairments

Benedict, Christian; Frey, William H.; Schiöth, Helgi; Schultes, Bernd et al.

Ingår i Experimental Gerontology, s. 112-115, 2011

• DOI för Intranasal insulin as a therapeutic option in the treatment of cognitive impairments

Long evolutionary conservation and considerable tissue specificity of several atypical solute carrier transporters

Sreedharan, Smitha; Stephansson, Olga; Schiöth, Helgi B.; Fredriksson, Robert

Ingår i Gene, s. 11-18, 2011

• DOI för Long evolutionary conservation and considerable tissue specificity of several atypical solute carrier transporters

Independent HHsearch, Needleman-Wunsch-based, and motif analyses reveal the overall hierarchy for most of the G protein-coupled receptor families

Nordström, Karl; Sällman Almén, Markus; Edstam, Monika; Fredriksson, Robert et al.

Ingår i Molecular biology and evolution, s. 2471-2480, 2011

Opioids as facilitators of feeding: Can any food be rewarding?

Olszewski, Pawel K.; Alsiö, Johan; Schiöth, Helgi B.; Levine, Allen S.

Ingår i Physiology and Behavior, s. 105-110, 2011

• DOI för Opioids as facilitators of feeding: Can any food be rewarding?

Comprehensive analysis of localization of 78 solute carrier genes throughout the subsections of the rat gastrointestinal tract

Cedernaes, Jonathan; Olszewski, Pawel K.; Sällman Almén, Markus; Stephansson, Olga et al.

Ingår i Biochemical and Biophysical Research Communications - BBRC, s. 702-707, 2011

• DOI för Comprehensive analysis of localization of 78 solute carrier genes throughout the subsections of the rat gastrointestinal tract

Fto colocalizes with a satiety mediator oxytocin in the brain and upregulates oxytocin gene expression

Olszewski, Pawel K.; Fredriksson, Robert; Eriksson, Jenny D.; Mitra, Anaya et al.

Ingår i Biochemical and Biophysical Research Communications - BBRC, s. 422-426, 2011

• DOI för Fto colocalizes with a satiety mediator oxytocin in the brain and upregulates oxytocin gene expression

Trends in the exploitation of novel drug targets

Rask-Andersen, Mathias; Sällman Almén, Markus; Schiöth, Helgi B.

Ingår i Nature reviews. Drug discovery, s. 579-590, 2011

• DOI för Trends in the exploitation of novel drug targets

Differential Neural Responses to Food Images in Women with Bulimia versus Anorexia Nervosa

Brooks, Samantha J.; O'Daly, Owen G.; Uher, Rudolf; Friederich, Hans-Christoph et al.

Ingår i PLOS ONE, 2011

• DOI för Differential Neural Responses to Food Images in Women with Bulimia versus Anorexia Nervosa

Reply to Braasch and Postlethwait: Evolutionary origin of the teleost A2 agouti genes (agouti signaling protein 2 and agouti-related protein 2) remains unclear

Schiöth, Helgi B.; Västermark, Åke; Cone, Roger D.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, 2011

• DOI för Reply to Braasch and Postlethwait: Evolutionary origin of the teleost A2 agouti genes (agouti signaling protein 2 and agouti-related protein 2) remains unclear

Associations between severity of obesity in childhood and adolescence, obesity onset andparental BMI: a longitudinal cohort study

Svensson, Viktoria; Jacobsson, Josefin A; Fredriksson, Robert; Danielsson, Pernilla et al.

Ingår i International Journal of Obesity, s. 46-52, 2011

• DOI för Associations between severity of obesity in childhood and adolescence, obesity onset andparental BMI: a longitudinal cohort study

Fto immunoreactivity is widespread in the rodent brain and abundant in feeding-related sites, but the number of Fto-positive cells is not affected by changes in energy balance

Olszewski, Pawel K.; Radomska, Katarzyna J.; Ghimire, Kedar; Klockars, Anica et al.

Ingår i Physiology and Behavior, s. 248-253, 2011

• DOI för Fto immunoreactivity is widespread in the rodent brain and abundant in feeding-related sites, but the number of Fto-positive cells is not affected by changes in energy balance

Independent HHsearch, Needleman-Wunsch-based, and motif analyses reveal the overall hierarchy for most of the G protein-coupled receptor families

Nordström, Karl; Sällman Almén, Markus; Edstam, Monika; Fredriksson, Robert et al.

Ingår i Molecular biology and evolution, s. 2471-2480, 2011

• DOI för Independent HHsearch, Needleman-Wunsch-based, and motif analyses reveal the overall hierarchy for most of the G protein-coupled receptor families

The early origin of melanocortin receptors, agouti-related peptide, agouti signalling peptide, and melanocortin receptor-accessory proteins, with emphasis on pufferfishes, elephant shark, lampreys, and amphioxus

Västermark, Åke; Schiöth, Helgi B

Ingår i European Journal of Pharmacology, s. 61-69, 2011

• DOI för The early origin of melanocortin receptors, agouti-related peptide, agouti signalling peptide, and melanocortin receptor-accessory proteins, with emphasis on pufferfishes, elephant shark, lampreys, and amphioxus

Melanocortin receptor subtypes in interrenal cells and corticotropic activity of α-melanocyte-stimulating hormones in barfin flounder, Verasper moseri

Kobayashi, Yuki; Chiba, Hiroaki; Yamanome, Takeshi; Schiöth, Helgi B. et al.

Ingår i General and Comparative Endocrinology, s. 558-568, 2011

• DOI för Melanocortin receptor subtypes in interrenal cells and corticotropic activity of α-melanocyte-stimulating hormones in barfin flounder, Verasper moseri

The solute carrier families have a remarkably long evolutionary history with the majority of the human families present before divergence of Bilaterian species

Höglund, Pär J.; Nordström, Karl J. V.; Schiöth, Helgi B.; Fredriksson, Robert

Ingår i Molecular biology and evolution, s. 1531-1541, 2011

• DOI för The solute carrier families have a remarkably long evolutionary history with the majority of the human families present before divergence of Bilaterian species

The G protein coupled receptor Gpr153 shares common evolutionary origin with Gpr162 and is highly expressed in central regions including the thalamus, cerebellum and the arcuate nucleus

Sreedharan, Smitha; Sällman Almén, Markus; Carlini, Valeria P; Haitina, Tatjana et al.

Ingår i The FEBS Journal, s. 4881-4894, 2011

• DOI för The G protein coupled receptor Gpr153 shares common evolutionary origin with Gpr162 and is highly expressed in central regions including the thalamus, cerebellum and the arcuate nucleus

Hippocampal effects of neuronostatin on memory, anxiety-like behavior and food intake in rats

Carlini, V. P.; Ghersi, M.; Gabach, L.; Schioth, Helgi B. et al.

Ingår i Neuroscience, s. 145-152, 2011

• DOI för Hippocampal effects of neuronostatin on memory, anxiety-like behavior and food intake in rats

Identification of somatostatin receptor type 5 gene polymorphisms associated with acromegaly

Ciganoka, Darja; Balcere, Inga; Kapa, Ivo; Peculis, Raitis et al.

Ingår i European Journal of Endocrinology, s. 517-525, 2011

• DOI för Identification of somatostatin receptor type 5 gene polymorphisms associated with acromegaly

Ghrelin inhibited serotonin release from hippocampal slices

Ghersi, Marisa Soledad; Casas, Sebastian M.; Escudero, Carla; Carlini, Valeria P. et al.

Ingår i Peptides, s. 2367-2371, 2011

• DOI för Ghrelin inhibited serotonin release from hippocampal slices

Glutamate, aspartate and nucleotide transporters in the SLC17 family form four main phylogenetic clusters: evolution and tissue expression

Sreedharan, Smitha; Shaik, Jafar H A; Olszewski, Pawel K; Levine, Allen S et al.

Ingår i BMC Genomics, s. 17, 2010

• DOI för Glutamate, aspartate and nucleotide transporters in the SLC17 family form four main phylogenetic clusters: evolution and tissue expression

The obesity gene, TMEM18, is of ancient origin, found in majority of neuronal cells in all major brain regions and associated with obesity in severely obese children

Almén, Markus Sällman; Jacobsson, Josefin A.; Shaik, Jafar H. A.; Olszewski, Pawel K. et al.

Ingår i BMC Medical Genetics, s. 58, 2010

• DOI för The obesity gene, TMEM18, is of ancient origin, found in majority of neuronal cells in all major brain regions and associated with obesity in severely obese children

SPRIT: Identifying horizontal gene transfer in rooted phylogenetic trees

Hill, Tobias; Nordström, Karl J V; Thollesson, Mikael; Säfström, Tommy M et al.

Ingår i BMC Evolutionary Biology, s. 42, 2010

• DOI för SPRIT: Identifying horizontal gene transfer in rooted phylogenetic trees

Molecular, Immunohistochemical, and Pharmacological Evidence of Oxytocin's Role as Inhibitor of Carbohydrate But Not Fat Intake

Olszewski, Pawel K.; Klockars, Anica; Olszewska, Agnieszka M.; Fredriksson, Robert et al.

Ingår i Endocrinology, s. 4736-4744, 2010

• DOI för Molecular, Immunohistochemical, and Pharmacological Evidence of Oxytocin's Role as Inhibitor of Carbohydrate But Not Fat Intake

Central nociceptin/orphanin FQ system elevates food consumption by both increasing energy intake and reducing aversive responsiveness

Olszewski, Pawel K; Grace, Martha K; Fard, Shahrzad Shirazi; Le Grevès, Madeleine et al.

Ingår i American Journal of Physiology. Regulatory Integrative and Comparative Physiology, 2010

• DOI för Central nociceptin/orphanin FQ system elevates food consumption by both increasing energy intake and reducing aversive responsiveness

Dopamine D1 receptor gene expression decreases in the nucleus accumbens upon long-term exposure to palatable food and differs depending on diet-induced obesity phenotype in rats

Alsiö, Johan; Olszewski, Pawel K.; Norbäck, A. H.; Gunnarsson, Z. E. A. et al.

Ingår i Neuroscience, s. 779-787, 2010

• DOI för Dopamine D1 receptor gene expression decreases in the nucleus accumbens upon long-term exposure to palatable food and differs depending on diet-induced obesity phenotype in rats

Chronic sugar intake dampens feeding-related activity of neurons synthesizing a satiety mediator, oxytocin

Mitra, Anaya; Gosnell, Blake A; Schiöth, Helgi B.; Grace, Martha K et al.

Ingår i Peptides, s. 1346-1352, 2010

• DOI för Chronic sugar intake dampens feeding-related activity of neurons synthesizing a satiety mediator, oxytocin

Ghrelin induced memory facilitation implicates nitric oxide synthase activation and decrease in the threshold to promote LTP in hippocampal dentate gyrus

Carlini, Valeria P.; Perez, Mariela F.; Salde, Estela; Schiöth, Helgi B. et al.

Ingår i Physiology and Behavior, s. 117-123, 2010

• DOI för Ghrelin induced memory facilitation implicates nitric oxide synthase activation and decrease in the threshold to promote LTP in hippocampal dentate gyrus

Differential expressions of melanocortin receptor subtypes in melanophores and xanthophores of barfin flounder

Kobayashi, Yuki; Tsuchiya, Keisuke; Yamanome, Takeshi; Schiöth, Helgi B. et al.

Ingår i General and Comparative Endocrinology, s. 133-142, 2010

• DOI för Differential expressions of melanocortin receptor subtypes in melanophores and xanthophores of barfin flounder

Identification of domains responsible for specific membrane transport and ligand specificity of the ACTH receptor (MC2R)

Fridmanis, Davids; Petrovska, Ramona; Kalnina, Ineta; Slaidina, Maija et al.

Ingår i Molecular and Cellular Endocrinology, s. 175-183, 2010

• DOI för Identification of domains responsible for specific membrane transport and ligand specificity of the ACTH receptor (MC2R)

MDMA (Ecstasy) decreases the number of neurons and stem cells in embryonic cortical cultures

Kindlundh-Högberg, Anna M. S.; Pickering, Chris; Wicher, Grzegorz; Hobér, David et al.

Ingår i Cellular and molecular neurobiology, s. 13-21, 2010

• DOI för MDMA (Ecstasy) decreases the number of neurons and stem cells in embryonic cortical cultures

Ghrelin and memory: differential effects on acquisition and retrieval

Carlini, Valeria P; Ghersi, Marisa; Schiöth, Helgi B; de Barioglio, Susana R

Ingår i Peptides, s. 1190-1193, 2010

• DOI för Ghrelin and memory: differential effects on acquisition and retrieval

Mapping the human membrane proteome: a majority of the human membrane proteins can be classified according to function and evolutionary origin

Almén, Markus Sällman; Nordström, Karl J V; Fredriksson, Robert; Schiöth, Helgi B

Ingår i BMC Biology, s. 50, 2009

• DOI för Mapping the human membrane proteome: a majority of the human membrane proteins can be classified according to function and evolutionary origin

Hypothalamic FTO is associated with the regulation of energy intake not feeding reward

Olszewski, Pawel K; Fredriksson, Robert; Olszewska, Agnieszka M; Stephansson, Olga et al.

Ingår i BMC Neuroscience, s. 129, 2009

• DOI för Hypothalamic FTO is associated with the regulation of energy intake not feeding reward

The G protein-coupled receptor subset of the dog genome is more similar to that in humans than rodents

Haitina, Tatjana; Fredriksson, Robert; Foord, Steven M.; Schiöth, Helgi B. et al.

Ingår i BMC Genomics, s. 24, 2009

• DOI för The G protein-coupled receptor subset of the dog genome is more similar to that in humans than rodents

Association between a rare SNP in the second intron of human Agouti related protein gene and increased BMI

Kalnina, Ineta; Kapa, Ivo; Pirags, Valdis; Ignatovica, Vita et al.

Ingår i BMC Medical Genetics, s. 63, 2009

• DOI för Association between a rare SNP in the second intron of human Agouti related protein gene and increased BMI

The common FTO variant rs9939609 is not associated with BMI in a longitudinal study on a cohort of Swedish men born 1920-1924

Jacobsson, Josefin A; Risérus, Ulf; Axelsson, Tomas; Lannfelt, Lars et al.

Ingår i BMC Medical Genetics, s. 131, 2009

• DOI för The common FTO variant rs9939609 is not associated with BMI in a longitudinal study on a cohort of Swedish men born 1920-1924

Anxiolytic response after palatable diet consumption but not food restriction in rats

Alsiö, Johan; Pickering, Christopher; Roman, Erika; Lindblom, Jonas et al.

Ingår i Appetite, s. 816-816, 2009

Critical evaluation of the FANTOM3 non-coding RNA transcripts

Nordström, Karl J V; Mirza, Majd A I; Almén, Markus Sällman; Gloriam, David E et al.

Ingår i Genomics, s. 169-176, 2009

• DOI för Critical evaluation of the FANTOM3 non-coding RNA transcripts

Memory impairment induced by IL-1beta is reversed by alpha-MSH through central melanocortin-4 receptors

Gonzalez, Patricia Verónica; Schiöth, Helgi Birgir; Lasaga, Mercedes; Scimonelli, Teresa Nieves

Ingår i Brain, behavior, and immunity, s. 817-822, 2009

• DOI för Memory impairment induced by IL-1beta is reversed by alpha-MSH through central melanocortin-4 receptors

Complexity of neural mechanisms underlying overconsumption of sugar in scheduled feeding: involvement of opioids, orexin, oxytocin and NPY

Olszewski, Pawel K; Shaw, Timothy J; Grace, Martha K; Höglund, Catherine E et al.

Ingår i Peptides, s. 226-233, 2009

• DOI för Complexity of neural mechanisms underlying overconsumption of sugar in scheduled feeding: involvement of opioids, orexin, oxytocin and NPY

Impact of nandrolone decanoate on gene expression in endocrine systems related to the adverse effects of anabolic androgenic steroids

Alsiö, Johan; Birgner, Carolina; Björkblom, Lars; Isaksson, Pernilla et al.

Ingår i Basic & Clinical Pharmacology & Toxicology, s. 307-314, 2009

• DOI för Impact of nandrolone decanoate on gene expression in endocrine systems related to the adverse effects of anabolic androgenic steroids

Sequence polymorphism in a marine bivalve (Perna canaliculus) orphan G protein-coupled receptor gene: preliminary description and possible implications

Fidler, Andrew E.; Schiöth, Helgi B.; Fredriksson, Robert

Ingår i New Zealand Journal of Marine and Freshwater Research, s. 953-964, 2009

The Secretin GPCRs descended from the family of Adhesion GPCRs

Nordström, Karl J V; Lagerström, Malin C; Wallér, Linn M J; Fredriksson, Robert et al.

Ingår i Molecular biology and evolution, s. 71-84, 2009

• DOI för The Secretin GPCRs descended from the family of Adhesion GPCRs

Inverse association of high-fat diet preference and anxiety-like behavior: a putative role for urocortin 2

Alsiö, Johan; Roman, Erika; Olszewski, Pawel K.; Jonsson, Petra et al.

Ingår i Genes, Brain and Behavior, s. 193-202, 2009

• DOI för Inverse association of high-fat diet preference and anxiety-like behavior: a putative role for urocortin 2

Motivation for sucrose in sated rats is predicted by low anxiety-like behavior

Alsiö, Johan; Pickering, Chris; Roman, Erika; Hulting, Anna-Lena et al.

Ingår i Neuroscience Letters, s. 193-197, 2009

• DOI för Motivation for sucrose in sated rats is predicted by low anxiety-like behavior

Withdrawal from free-choice high-fat high-sugar diet induces craving only in obesity-prone animals

Pickering, Chris; Alsiö, Johan; Hulting, Anna-Lena; Schiöth, Helgi B

Ingår i Psychopharmacology, s. 431-443, 2009

• DOI för Withdrawal from free-choice high-fat high-sugar diet induces craving only in obesity-prone animals

Melanocortin peptides affect the motivation to feed in rainbow trout (Oncorhynchus mykiss)

Schjolden, Joachim; Schiöth, Helgi B.; Larhammar, Dan; Winberg, Svante et al.

Ingår i General and Comparative Endocrinology, s. 134-138, 2009

• DOI för Melanocortin peptides affect the motivation to feed in rainbow trout (Oncorhynchus mykiss)

Restricted cortical and amygdaloid removal of vesicular glutamate transporter 2 in preadolescent mice impacts dopaminergic activity and neuronal circuitry of higher brain function

Wallén-Mackenzie, Åsa; Nordenankar, Karin; Fejgin, Kim; Lagerström, Malin C et al.

Ingår i Journal of Neuroscience, s. 2238-2251, 2009

• DOI för Restricted cortical and amygdaloid removal of vesicular glutamate transporter 2 in preadolescent mice impacts dopaminergic activity and neuronal circuitry of higher brain function

Central ghrelin increases anxiety in the Open Field test and impairs retention memory in a passive avoidance task in neonatal chicks

Carvajal, Pedro; Carlini, Valeria P.; Schiöth, Helgi B.; de Barioglio, Susana R. et al.

Ingår i Neurobiology of Learning and Memory, s. 402-407, 2009

• DOI för Central ghrelin increases anxiety in the Open Field test and impairs retention memory in a passive avoidance task in neonatal chicks

The amphioxus (Branchiostoma floridae) genome contains a highly diversified set of G protein-coupled receptors

Nordström, Karl J V; Fredriksson, Robert; Schiöth, Helgi B

Ingår i BMC Evolutionary Biology, s. 9, 2008

• DOI för The amphioxus (Branchiostoma floridae) genome contains a highly diversified set of G protein-coupled receptors

Extensive neuroadaptive changes in cortical gene-transcript expressions of the glutamate system in response to repeated intermittent MDMA administration in adolescent rats

Kindlundh-Högberg, Anna M S; Blomqvist, Anna; Malki, Rana; Schiöth, Helgi B

Ingår i BMC Neuroscience, s. 39, 2008

• DOI för Extensive neuroadaptive changes in cortical gene-transcript expressions of the glutamate system in response to repeated intermittent MDMA administration in adolescent rats

Expression profile of the entire family of Adhesion G protein-coupled receptors in mouse and rat

Haitina, Tatjana; Olsson, Fredrik; Stephansson, Olga; Alsiö, Johan et al.

Ingår i BMC Neuroscience, s. 43, 2008

• DOI för Expression profile of the entire family of Adhesion G protein-coupled receptors in mouse and rat

The Adhesion GPCR GPR125 is specifically expressed in the choroid plexus and is upregulated following brain injury

Pickering, Chris; Hägglund, Maria; Szmydynger-Chodobska, Joanna; Marques, Fernanda et al.

Ingår i BMC Neuroscience, s. 97, 2008

• DOI för The Adhesion GPCR GPR125 is specifically expressed in the choroid plexus and is upregulated following brain injury

The solute carrier (SLC) complement of the human genome: phylogenetic classification reveals four major families

Fredriksson, Robert; Nordström, Karl J V; Stephansson, Olga; Hägglund, Maria G A et al.

Ingår i FEBS Letters, s. 3811-3816, 2008

• DOI för The solute carrier (SLC) complement of the human genome: phylogenetic classification reveals four major families

Food deprivation increases the expression of melanocortin-4 receptor in the liver of barfin flounder, Verasper moseri

Kobayashi, Yuki; Tsuchiya, Keisuke; Yamanome, Takeshi; Schiöth, Helgi B et al.

Ingår i General and Comparative Endocrinology, s. 280-287, 2008

• DOI för Food deprivation increases the expression of melanocortin-4 receptor in the liver of barfin flounder, Verasper moseri

Novel genetic variant in FTO influences insulin levels and insulin resistance in severely obese children and adolescents.

Jacobsson, J. A.; Klovins, Janis; Kapa, I.; Danielsson, P et al.

Ingår i International Journal of Obesity, s. 1730-1735, 2008

• DOI för Novel genetic variant in FTO influences insulin levels and insulin resistance in severely obese children and adolescents.

The relative impact of chronic food restriction and acute food deprivation on plasma hormone levels and hypothalamic neuropeptide expression

Johansson, Andreas; Fredriksson, Robert; Winnergren, Sonja; Hulting, Anna-Lena et al.

Ingår i Peptides, s. 1588-1595, 2008

• DOI för The relative impact of chronic food restriction and acute food deprivation on plasma hormone levels and hypothalamic neuropeptide expression

Major gender difference in association of FTO gene variant among severely obese children with obesity and obesity related phenotypes.

Jacobsson, Josefin A.; Danielsson, Pernilla; Svensson, Victoria; Klovins, Janis et al.

Ingår i Biochemical and Biophysical Research Communications - BBRC, s. 476-482, 2008

• DOI för Major gender difference in association of FTO gene variant among severely obese children with obesity and obesity related phenotypes.

The obesity gene, FTO, is of ancient origin, up-regulated during food deprivation and expressed in neurons of feeding-related nuclei of the brain

Fredriksson, Robert; Hägglund, Maria; Olszewski, Pawel K; Stephansson, Olga et al.

Ingår i Endocrinology, s. 2062-71, 2008

• DOI för The obesity gene, FTO, is of ancient origin, up-regulated during food deprivation and expressed in neurons of feeding-related nuclei of the brain

The anabolic androgenic steroid nandrolone decanoate affects mRNA expression of dopaminergic but not serotonergic receptors

Birgner, Carolina; Kindlundh-Högberg, Anna; Alsiö, Johan; Lindblom, Jonas et al.

Ingår i Brain Research, s. 221-228, 2008

• DOI för The anabolic androgenic steroid nandrolone decanoate affects mRNA expression of dopaminergic but not serotonergic receptors

Reduced activity of monoamine oxidase in the rat brain following repeated nandrolone decanoate administration

Birgner, Carolina; Kindlundh-Högberg, Anna; Oreland, Lars; Alsiö, Johan et al.

Ingår i Brain Research, s. 103-110, 2008

• DOI för Reduced activity of monoamine oxidase in the rat brain following repeated nandrolone decanoate administration

Allelotyping by massively parallel pyrosequencing of SNP-carrying trinucleotide threads

Pettersson, Erik; Zajac, Pawel; Ståhl, Patrik L; Jacobsson, Josefin A et al.

Ingår i Human Mutation, s. 323-329, 2008

• DOI för Allelotyping by massively parallel pyrosequencing of SNP-carrying trinucleotide threads

The G protein-coupled receptor subset of the rat genome

Gloriam, David E; Fredriksson, Robert; Schiöth, Helgi B

Ingår i BMC Genomics, s. 338, 2007

• DOI för The G protein-coupled receptor subset of the rat genome

Functional characterization of two melanocortin (MC) receptors in lamprey showing orthology to the MC1 and MC4 receptor subtypes

Haitina, Tatjana; Klovins, Janis; Takahashi, Akiyoshi; Löwgren, Maja et al.

Ingår i BMC Evolutionary Biology, s. 101, 2007

• DOI för Functional characterization of two melanocortin (MC) receptors in lamprey showing orthology to the MC1 and MC4 receptor subtypes

Anxiety-like behaviour predicts the preference for a high-carbohydrate diet in outbred rats

Alsiö, Johan; Roman, Erika; Fredriksson, Robert; Hulting, Anna-Lena et al.

Ingår i Behavioural Pharmacology, 2007

The melanin-concentrating hormone receptor 2 (MCH-R2) mediates the effect of MCH to control body color for background adaptation in the barfin flounder

Takahashi, Akiyoshi; Kosugi, Takayoshi; Kobayashi, Yuki; Yamanome, Takeshi et al.

Ingår i General and Comparative Endocrinology, s. 210-219, 2007

• DOI för The melanin-concentrating hormone receptor 2 (MCH-R2) mediates the effect of MCH to control body color for background adaptation in the barfin flounder

To press or not to press? Differential receptor expression and response to novelty in rats learning an operant response for reward

Pickering, Chris; Avesson, Lotta; Lindblom, Jonas; Liljequist, Sture et al.

Ingår i Neurobiology of Learning and Memory, s. 181-191, 2007

• DOI för To press or not to press? Differential receptor expression and response to novelty in rats learning an operant response for reward

Formation of new genes explains lower intron density in mammalian Rhodopsin G protein-coupled receptors

Fridmanis, Davids; Fredriksson, Robert; Kapa, Ivo; Schiöth, Helgi B. et al.

Ingår i Molecular Phylogenetics and Evolution, s. 864-880, 2007

• DOI för Formation of new genes explains lower intron density in mammalian Rhodopsin G protein-coupled receptors

The evolutionary history and tissue mapping of GPR123: specific CNS expression pattern predominantly in thalamic nuclei and regions containing large pyramidal cells

Lagerström, Malin C.; Rabe, Nadine; Haitina, Tatjana; Kalnina, Ineta et al.

Ingår i Journal of Neurochemistry, s. 1129-1142, 2007

• DOI för The evolutionary history and tissue mapping of GPR123: specific CNS expression pattern predominantly in thalamic nuclei and regions containing large pyramidal cells

Identification of novel splice variants of Adhesion G protein-coupled receptors

Bjarnadóttir, Thóra K.; Geirardsdóttir, Kristín; Ingemansson, Malena; Mirza, Majd A. I. et al.

Ingår i Gene, s. 38-48, 2007

• DOI för Identification of novel splice variants of Adhesion G protein-coupled receptors

Mining the gene repertoire and ESTs for G protein-coupled receptors with evolutionary perspective

Schiöth, Helgi B.; Nordström, K. J. V.; Fredriksson, Robert

Ingår i Acta Physiologica, s. 21-31, 2007

• DOI för Mining the gene repertoire and ESTs for G protein-coupled receptors with evolutionary perspective

The role of hypothalamic peptide gene expression in alcohol self-administration behavior.

Pickering, Chris; Avesson, Lotta; Liljequist, Sture; Lindblom, Jonas et al.

Ingår i Peptides, s. 2361-2371, 2007

• DOI för The role of hypothalamic peptide gene expression in alcohol self-administration behavior.

Activation of melanocortin 4 receptors reduces the inflammatory response and prevents apoptosis induced by lipopolysaccharide and interferon-gamma in astrocytes

Caruso, Carla; Durand, Daniela; Schiöth, Helgi B.; Rey, Rodolfo et al.

Ingår i Endocrinology, s. 4918-4926, 2007

• DOI för Activation of melanocortin 4 receptors reduces the inflammatory response and prevents apoptosis induced by lipopolysaccharide and interferon-gamma in astrocytes

Further evidence for ancient role of ACTH peptides at melanocortin (MC) receptors; pharmacology of dogfish and lamprey peptides at dogfish MC receptors

Haitina, Tatjana; Takahashi, Akiyoshi; Holmén, Linnea; Enberg, Johan et al.

Ingår i Peptides, s. 798-805, 2007

• DOI för Further evidence for ancient role of ACTH peptides at melanocortin (MC) receptors; pharmacology of dogfish and lamprey peptides at dogfish MC receptors

The G protein-coupled receptor subset of the chicken genome

Lagerström, Malin C.; Hellström, Anders R.; Gloriam, David E.; Larsson, Thomas P. et al.

Ingår i PloS Computational Biology, 2006

• DOI för The G protein-coupled receptor subset of the chicken genome

Genetic algorithm for large-scale maximum parsimony phylogenetic analysis of proteins

Hill, Tobias; Lundgren, Andor; Fredriksson, Robert; Schiöth, Helgi B.

Ingår i Biochimica et Biophysica Acta - General Subjects, s. 19-29, 2005

• DOI för Genetic algorithm for large-scale maximum parsimony phylogenetic analysis of proteins

Evaluation of EST-data using the genome assembly

Murray, Christian; Larsson, Thomas; Hill, Tobias; Björklind, Rikard et al.

Ingår i Biochemical and Biophysical Research Communications - BBRC, s. 1566-1576, 2005

• DOI för Evaluation of EST-data using the genome assembly

Cloning, tissue distribution, pharmacology and three-dimensional modelling of melanocortin receptors 4 and 5 in rainbow trout suggest close evolutionary relationship of these subtypes

Haitina, Tatjana; Klovins, Janis; Andersson, Jan; Fredriksson, Robert et al.

Ingår i Biochemical Journal, s. 475-486, 2004

• DOI för Cloning, tissue distribution, pharmacology and three-dimensional modelling of melanocortin receptors 4 and 5 in rainbow trout suggest close evolutionary relationship of these subtypes

Pharmacological characterization of loss of function mutations of the human melanocortin 1 receptor that are associated with red hair

Ringholm, Aneta; Klovins, Janis; Rudzish, Richard; Phillips, Sion et al.

Ingår i Journal of Investigative Dermatology, s. 917-923, 2004

• DOI för Pharmacological characterization of loss of function mutations of the human melanocortin 1 receptor that are associated with red hair

The human and mouse repertoire of the adhesion family of G-protein-coupled receptors

Bjarnadóttir, Thóra K.; Fredriksson, Robert; Höglund, Pär J.; Gloriam, David E. et al.

Ingår i Genomics, s. 23-33, 2004

• DOI för The human and mouse repertoire of the adhesion family of G-protein-coupled receptors

High affinity agonistic metal ion binding sites within the melanocortin 4 receptor illustrate conformational change of transmembrane region 3

Lagerström, Malin C.; Klovins, Janis; Fredriksson, Robert; Fridmanis, Davids et al.

Ingår i Journal of Biological Chemistry, s. 51521-51526, 2003

• DOI för High affinity agonistic metal ion binding sites within the melanocortin 4 receptor illustrate conformational change of transmembrane region 3

Comprehensive overview of the toxicities of small-molecule cryoprotectants for carnivorous spermatozoa: foundation for computational cryobiotechnology

Karimi, Isaac; Mohammad, Layth Jasim; Suvitha, A.; Haidari, Zohreh et al.

Ingår i Frontiers in Toxicology, 2025

• DOI för Comprehensive overview of the toxicities of small-molecule cryoprotectants for carnivorous spermatozoa: foundation for computational cryobiotechnology
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Disease-modifying pharmacological treatments of type 1 diabetes: Molecular mechanisms, target checkpoints, and possible combinatorial treatments

Kosheleva, Liudmila; Koshelev, Daniil; Lagunas-Rangel, Francisco Alejandro; Levit, Shmuel et al.

Ingår i Pharmacological Reviews, 2025

• DOI för Disease-modifying pharmacological treatments of type 1 diabetes: Molecular mechanisms, target checkpoints, and possible combinatorial treatments
• Ladda ner fulltext (pdf) av Disease-modifying pharmacological treatments of type 1 diabetes: Molecular mechanisms, target checkpoints, and possible combinatorial treatments

Inulin as a Biopolymer; Chemical Structure, Anticancer Effects, Nutraceutical Potential and Industrial Applications: A Comprehensive Review

Karimi, Isaac; Ghowsi, Mahnaz; Mohammed, Layth Jasim; Haidari, Zohreh et al.

Ingår i Polymers, 2025

• DOI för Inulin as a Biopolymer; Chemical Structure, Anticancer Effects, Nutraceutical Potential and Industrial Applications: A Comprehensive Review
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Recent advances in gold nanostructure-based biosensors in detecting diabetes biomarkers

Jamshidnejad-Tosaramandani, Tahereh; Kashanian, Soheila; Omidfar, Kobra; Schiöth, Helgi B.

Ingår i Frontiers in Bioscience, 2024

• DOI för Recent advances in gold nanostructure-based biosensors in detecting diabetes biomarkers
• Ladda ner fulltext (pdf) av Recent advances in gold nanostructure-based biosensors in detecting diabetes biomarkers

Depression clinical trials worldwide: a systematic analysis of the ICTRP and comparison with ClinicalTrials.gov

Namiot, Eugenia; Smirnovová, Diana; Sokolov, Aleksandr V.; Chubarev, Vladimir N. et al.

Ingår i Translational Psychiatry, 2024

• DOI för Depression clinical trials worldwide: a systematic analysis of the ICTRP and comparison with ClinicalTrials.gov
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A neuroinflammatory compulsivity model of anorexia nervosa (NICAN)

Brooks, Samantha; Dahl, K.; Dudley-Jones, R.; Schiöth, Helgi

Ingår i Neuroscience and Biobehavioral Reviews, 2024

• DOI för A neuroinflammatory compulsivity model of anorexia nervosa (NICAN)
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Exploring sex differences: insights into gene expression, neuroanatomy, neurochemistry, cognition, and pathology

Lafta, Muataz S.; Mwinyi, Jessica; Affatato, Oreste; Rukh, Gull et al.

Ingår i Frontiers in Neuroscience, 2024

• DOI för Exploring sex differences: insights into gene expression, neuroanatomy, neurochemistry, cognition, and pathology
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The effect of sunscreen 4-methylbenzylidene camphor in different and reproductive models, its bioaccumulation and molecular effects on ligand-receptor interaction, and protein expression

Lax, Cassandra; Wicksell, Elin; Grip, Anastasia; Niemi, Jenni Viivi Linnea et al.

Ingår i Basic & Clinical Pharmacology & Toxicology, s. 130-141, 2023

• DOI för The effect of sunscreen 4-methylbenzylidene camphor in different and reproductive models, its bioaccumulation and molecular effects on ligand-receptor interaction, and protein expression
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The Epigenetics of Migraine

Zobdeh, Farzin; Eremenko, Ivan I.; Akan, Mikail A.; Tarasov, Vadim V. et al.

Ingår i International Journal of Molecular Sciences, 2023

• DOI för The Epigenetics of Migraine
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Nanoparticles in Clinical Trials: Analysis of Clinical Trials, FDA Approvals and Use for COVID-19 Vaccines

Namiot, Eugenia D.; Sokolov, Aleksandr V.; Chubarev, Vladimir N.; Tarasov, Vadim V. et al.

Ingår i International Journal of Molecular Sciences, 2023

• DOI för Nanoparticles in Clinical Trials: Analysis of Clinical Trials, FDA Approvals and Use for COVID-19 Vaccines
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Genetics of anorexia nervosa: An overview of genome-wide association studies and emerging biological links

de Jorge Martínez, Clara; Rukh, Gull; Williams, Michael J.; Gaudio, Santino et al.

Ingår i Journal of genetics and genomics = Yi chuan xue bao, s. 1-12, 2022

• DOI för Genetics of anorexia nervosa: An overview of genome-wide association studies and emerging biological links

The potential interaction of environmental pollutants and circadian rhythm regulations that may cause leukemia

Lagunas-Rangel, Francisco Alejandro; Kudłak, Błażej; Liu, Wen; Williams, Michael J. et al.

Ingår i Critical reviews in environmental science and technology, s. 4094-4112, 2022

• DOI för The potential interaction of environmental pollutants and circadian rhythm regulations that may cause leukemia
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Dissecting the Molecular Mechanisms Surrounding Post-COVID-19 Syndrome and Neurological Features

Mohamed, Mohamed S.; Johansson, Anton; Jonsson, Jörgen; Schiöth, Helgi B.

Ingår i International Journal of Molecular Sciences, 2022

• DOI för Dissecting the Molecular Mechanisms Surrounding Post-COVID-19 Syndrome and Neurological Features
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Pharmacogenetics and Pain Treatment with a Focus on Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and Antidepressants: A Systematic Review

Zobdeh, Farzin; Eremenko, Ivan I.; Akan, Mikail A.; Tarasov, Vadim V. et al.

Ingår i Pharmaceutics, 2022

• DOI för Pharmacogenetics and Pain Treatment with a Focus on Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and Antidepressants: A Systematic Review
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Challenges in Analyzing Functional Epigenetic Data in Perspective of Adolescent Psychiatric Health

Ciuculete, Diana-Maria; Mwinyi, Jessica; Schiöth, Helgi B.

Ingår i International Journal of Molecular Sciences, 2022

• DOI för Challenges in Analyzing Functional Epigenetic Data in Perspective of Adolescent Psychiatric Health
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Statins and cognition: Modifying factors and possible underlying mechanisms

Jamshidnejad-Tosaramandani, Tahereh; Kashanian, Soheila; Al-Sabri, Mohamed H.; Krocianova, Daniela et al.

Ingår i Frontiers in Aging Neuroscience, 2022

• DOI för Statins and cognition: Modifying factors and possible underlying mechanisms
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Trends in Antidiabetic Drug Discovery: FDA Approved Drugs, New Drugs in Clinical Trials and Global Sales

Dahlén, Amelia; Dashi, Giovanna; Maslov, Ivan; Attwood, Misty M. et al.

Ingår i Frontiers in Pharmacology, 2022

• DOI för Trends in Antidiabetic Drug Discovery: FDA Approved Drugs, New Drugs in Clinical Trials and Global Sales
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Pharmacogenetics in Primary Headache Disorders

Belyaeva, Irina I.; Subbotina, Anna G.; Eremenko, Ivan I.; Tarasov, Vadim V. et al.

Ingår i Frontiers in Pharmacology, 2022

• DOI för Pharmacogenetics in Primary Headache Disorders
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Treatment of ADHD: Drugs, psychological therapies, devices, complementary and alternative methods as well as the trends in clinical trials

Nazarova, Victoria A.; Sokolov, Aleksandr V.; Chubarev, Vladimir N.; Tarasov, Vadim V. et al.

Ingår i Frontiers in Pharmacology, 2022

• DOI för Treatment of ADHD: Drugs, psychological therapies, devices, complementary and alternative methods as well as the trends in clinical trials
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Recent developments of phosphodiesterase inhibitors: Clinical trials, emerging indications and novel molecules

Bondarev, Andrey D.; Attwood, Misty M.; Jonsson, Jörgen; Chubarev, Vladimir N. et al.

Ingår i Frontiers in Pharmacology, 2022

• DOI för Recent developments of phosphodiesterase inhibitors: Clinical trials, emerging indications and novel molecules
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Role of the synergistic interactions of environmental pollutants in the development of cancer

Lagunas-Rangel, Francisco Alejandro; Niemi, Jenni Viivi Linnea; Kudłak, Błażej; Williams, Michael J. et al.

Ingår i GeoHealth, 2022

• DOI för Role of the synergistic interactions of environmental pollutants in the development of cancer
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Subliminal Emotional Faces Elicit Predominantly Right-Lateralized Amygdala Activation: A Systematic Meta-Analysis of fMRI Studies

Dahlén, Amelia; Schofield, Aphra; Schiöth, Helgi B.; Brooks, Samantha J.

Ingår i Frontiers in Neuroscience, 2022

• DOI för Subliminal Emotional Faces Elicit Predominantly Right-Lateralized Amygdala Activation: A Systematic Meta-Analysis of fMRI Studies
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