Michael Welsh

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

He, Liqun; Testini, Chiara; Hekmati, Neda; Bonello, Altea et al.

Part of Molecular Oncology, 2025

• DOI for Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity
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Risk assessment for vaccination programmes in a pandemic: A Swedish model for efficacy and safety during COVID-19

Wikström, Gerhard; Welsh, Michael

Part of Upsala Journal of Medical Sciences, 2025

• DOI for Risk assessment for vaccination programmes in a pandemic: A Swedish model for efficacy and safety during COVID-19
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Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis

Jin, Yi; Ding, Yindi; Richards, Mark; Kaakinen, Mika et al.

Part of Nature Cardiovascular Research, p. 1156-1173, 2022

• DOI for Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis
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The retirement of Editor-in-Chief Arne Andersson, Upsala Journal of Medical Sciences 2006–2022: an amazing journey under Arne's stewardship

Wikström, Gerhard; Welsh, Michael

Part of Upsala Journal of Medical Sciences, 2022

• DOI for The retirement of Editor-in-Chief Arne Andersson, Upsala Journal of Medical Sciences 2006–2022: an amazing journey under Arne's stewardship
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Perspectives on Vascular Regulation of Mechanisms Controlling Selective Immune Cell Function in the Tumor Immune Response

Welsh, Michael

Part of International Journal of Molecular Sciences, 2022

• DOI for Perspectives on Vascular Regulation of Mechanisms Controlling Selective Immune Cell Function in the Tumor Immune Response
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Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

He, Liqun; Testini, Chiara; Hekmati, Neda; Bonello, Altea et al.

Part of Molecular Oncology, 2025

• DOI for Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity
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Risk assessment for vaccination programmes in a pandemic: A Swedish model for efficacy and safety during COVID-19

Wikström, Gerhard; Welsh, Michael

Part of Upsala Journal of Medical Sciences, 2025

• DOI for Risk assessment for vaccination programmes in a pandemic: A Swedish model for efficacy and safety during COVID-19
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Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis

Jin, Yi; Ding, Yindi; Richards, Mark; Kaakinen, Mika et al.

Part of Nature Cardiovascular Research, p. 1156-1173, 2022

• DOI for Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis
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The retirement of Editor-in-Chief Arne Andersson, Upsala Journal of Medical Sciences 2006–2022: an amazing journey under Arne's stewardship

Wikström, Gerhard; Welsh, Michael

Part of Upsala Journal of Medical Sciences, 2022

• DOI for The retirement of Editor-in-Chief Arne Andersson, Upsala Journal of Medical Sciences 2006–2022: an amazing journey under Arne's stewardship
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Mouse Breast Carcinoma Monocytic/Macrophagic Myeloid-Derived Suppressor Cell Infiltration as a Consequence of Endothelial Dysfunction in Shb-Deficient Endothelial Cells Increases Tumor Lung Metastasis

He, Qi; Jamalpour, Maria; Bergquist, Eric; Anderson, Robin et al.

Part of International Journal of Molecular Sciences, 2021

• DOI for Mouse Breast Carcinoma Monocytic/Macrophagic Myeloid-Derived Suppressor Cell Infiltration as a Consequence of Endothelial Dysfunction in Shb-Deficient Endothelial Cells Increases Tumor Lung Metastasis
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The Felicitous Success of the Subsection Molecular Oncology of International Journal of Molecular Sciences

Welsh, Michael

Part of International Journal of Molecular Sciences, 2021

• DOI for The Felicitous Success of the Subsection Molecular Oncology of International Journal of Molecular Sciences
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Pericyte dysfunction due to Shb gene deficiency increases B16F10 melanoma lung metastasis

He, Qi; Li, Xiujuan; He, Liqun; Li, Yousheng et al.

Part of International Journal of Cancer, p. 2634-2644, 2020

• DOI for Pericyte dysfunction due to Shb gene deficiency increases B16F10 melanoma lung metastasis
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Absence of the Shb gene in mixed-lineage leukemia MLL-AF9 cells increases latency in mice despite higher proliferation rates in vitro

Jamalpour, Maria; Bergquist, Eric; Welsh, Michael

Part of Experimental Cell Research, 2020

• DOI for Absence of the Shb gene in mixed-lineage leukemia MLL-AF9 cells increases latency in mice despite higher proliferation rates in vitro
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The Cdh5-CreERT2 transgene causes conditional Shb gene deletion in hematopoietic cells with consequences for immune cell responses to tumors

He, Qi; Li, Xiujuan; Singh, Kailash; Luo, Zhengkang et al.

Part of Scientific Reports, 2019

• DOI for The Cdh5-CreERT2 transgene causes conditional Shb gene deletion in hematopoietic cells with consequences for immune cell responses to tumors
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Temporal Dynamics of VEGFA-Induced VEGFR2/FAK Co-Localization Depend on SHB

Pietilä, Ilkka; van Mourik, Djenolan; Tamelander, Andreas; Kriz, Vitezslav et al.

Part of Cells, 2019

• DOI for Temporal Dynamics of VEGFA-Induced VEGFR2/FAK Co-Localization Depend on SHB
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Pro-tumoral immune cell alterations in wild type and Shb-deficient mice in response to 4T1 breast carcinomas

Li, Xiujuan; Singh, Kailash; Luo, Zhengkang; Mejia Cordova, Mariela et al.

Part of Oncotarget, p. 18720-18733, 2018

• DOI for Pro-tumoral immune cell alterations in wild type and Shb-deficient mice in response to 4T1 breast carcinomas
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Leukocyte differentiation by histidine-rich glycoprotein/stanniocalcin-2 complex regulates murine glioma growth through modulation of anti-tumor immunity

Roche, Francis P.; Pietilä, Ilkka; Kaito, Hiroshi; Sjöström, Elisabet O. et al.

Part of Molecular Cancer Therapeutics, p. 1961-1972, 2018

• DOI for Leukocyte differentiation by histidine-rich glycoprotein/stanniocalcin-2 complex regulates murine glioma growth through modulation of anti-tumor immunity
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Disparate effects of Shb-gene deficiency on disease characteristics in murine models of myeloid, B-cell and T-cell leukemia

Jamalpour, Maria; Li, Xiujuan; Gustafsson, Karin; Tyner, Jeffrey et al.

Part of Tumor Biology, p. 1-13, 2018

• DOI for Disparate effects of Shb-gene deficiency on disease characteristics in murine models of myeloid, B-cell and T-cell leukemia
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Tumor SHB gene expression affects disease characteristics in human acute myeloid leukemia

Jamalpour, Maria; Li, Xiujuan; Cavelier, Lucia; Gustafsson, Karin et al.

Part of Tumor Biology, 2017

• DOI for Tumor SHB gene expression affects disease characteristics in human acute myeloid leukemia
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Maintenance of hematopoietic stem cell dormancy: yet another role for the macrophage

Gustafsson, Karin; Welsh, Michael

Part of stem cell investigation, 2016

• DOI for Maintenance of hematopoietic stem cell dormancy: yet another role for the macrophage

Claes Hellerström and Cartesian Diver respirometry

Welsh, Michael

Part of Upsala Journal of Medical Sciences, p. 77-80, 2016

• DOI for Claes Hellerström and Cartesian Diver respirometry

Identification and characterization of VEGF-A-responsive neutrophils expressing CD49d, VEGFR1, and CXCR4 in mice and humans

Massena, Sara; Christoffersson, Gustaf; Vågesjö, Evelina; Seignez, Cédric et al.

Part of Blood, p. 2016-2026, 2015

• DOI for Identification and characterization of VEGF-A-responsive neutrophils expressing CD49d, VEGFR1, and CXCR4 in mice and humans

Shb deficiency in endothelium but not in leukocytes is responsible for impaired vascular performance during hindlimb ischemia.

Nikpour, Maryam; Gustafsson, Karin; Vågesjö, Evelina; Seignez, Cedric et al.

Part of Acta Physiologica, p. 200-209, 2015

• DOI for Shb deficiency in endothelium but not in leukocytes is responsible for impaired vascular performance during hindlimb ischemia.
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Vascular dysfunction and increased metastasis of B16F10 melanomas in Shb deficient mice as compared with their wild type counterparts

Zang, Guangxiang; Gustafsson, Karin; Jamalpour, Maria; Hong, Jongwook et al.

Part of BMC Cancer, 2015

• DOI for Vascular dysfunction and increased metastasis of B16F10 melanomas in Shb deficient mice as compared with their wild type counterparts
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The Src homology-2 protein Shb modulates focal adhesion kinase signaling in a BCR-ABL myeloproliferative disorder causing accelerated progression of disease

Gustafsson, Karin; Jamalpour, Maria; Trinh, Camilla; Kharas, Michael G et al.

Part of Journal of Hematology & Oncology, p. 45, 2014

• DOI for The Src homology-2 protein Shb modulates focal adhesion kinase signaling in a BCR-ABL myeloproliferative disorder causing accelerated progression of disease
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Absence of the adaptor protein Shb potentiates the T_H2 response in a mouse model of atopic dermatitis

Gustafsson, Karin; Willebrand, Elsa; Welsh, Michael

Part of Immunology, p. 33-41, 2014

• DOI for Absence of the adaptor protein Shb potentiates the T_H2 response in a mouse model of atopic dermatitis
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Absence of Shb impairs insulin secretion by elevated FAK activity in pancreatic islets

Alenkvist, Ida; Dyachok, Oleg; Tian, Geng; Li, Jia et al.

Part of Journal of Endocrinology, p. 267-275, 2014

• DOI for Absence of Shb impairs insulin secretion by elevated FAK activity in pancreatic islets
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Role of Src homology 2 domain-containing protein B in the regulation of GFR and renal afferent arteriole responsiveness

Gao, Xiang; Sallstrom, Johan; Ma, Zufu; Welsh, Michael et al.

Part of The FASEB Journal, 2014

The Src Homology 2 Protein Shb Promotes Cell Cycle Progression In Murine Hematopoietic Stem Cells By Regulation Of Focal Adhesion Kinase Activity

Gustafsson, Karin; Heffner, Garrett; Wenzel, Pamela L.; Curran, Matthew et al.

Part of Experimental Cell Research, p. 1852-1864, 2013

• DOI for The Src Homology 2 Protein Shb Promotes Cell Cycle Progression In Murine Hematopoietic Stem Cells By Regulation Of Focal Adhesion Kinase Activity
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Absence of the Shb adaptor protein accelerates leukemia progression by control of cytokine responses

Gustafsson, Karin; Jamalpour, Maria; Welsh, Michael

Part of Experimental Hematology, 2013

Aberrant association between vascular endothelial growth factor receptor-2 and VE-cadherin in response to vascular endothelial growth factor-a in Shb-deficient lung endothelial cells

Zang, Guangxiang; Christoffersson, Gustaf; Tian, Geng; Harun-Or-Rashid, Mohammad et al.

Part of Cellular Signalling, p. 85-92, 2013

• DOI for Aberrant association between vascular endothelial growth factor receptor-2 and VE-cadherin in response to vascular endothelial growth factor-a in Shb-deficient lung endothelial cells
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The mechanisms of VEGF-A-induced recruitment of pro-angiogenic neutrophils

Massena, Sara; Christoffersson, Gustaf; Vågesjö, Evelina; Gustafsson, Karin et al.

Part of European Journal of Clinical Investigation, p. 27-27, 2013

SHB deficient mice display an increased GFR and augmented renal arteriolar contractions to both Adenosine and Ang II

Gao, Xiang; Sallstrom, Johan; Ma, Zufu; Welsh, Michael et al.

Part of The FASEB Journal, p. 909.14, 2013

Heterogeneity among RIP-Tag2 insulinomas allows vascular endothelial growth factor-A independent tumor expansion as revealed by studies in Shb mutant mice: implications for tumor angiogenesis

Åkerblom, Björn; Zang, Guangxiang; Zhuang, Zhen W.; Calounova, Gabriela et al.

Part of Molecular Oncology, p. 333-346, 2012

• DOI for Heterogeneity among RIP-Tag2 insulinomas allows vascular endothelial growth factor-A independent tumor expansion as revealed by studies in Shb mutant mice: implications for tumor angiogenesis
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Vascular adaptation to a dysfunctional endothelium as a consequence of Shb deficiency

Christoffersson, Gustav; Zang, Guangxiang; Zhuang, Zhen W.; Vågesjö, Evelina et al.

Part of Angiogenesis, p. 469-480, 2012

• DOI for Vascular adaptation to a dysfunctional endothelium as a consequence of Shb deficiency
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Shb deficient mice display an augmented T_H2 response in peripheral CD4+ T cells

Gustafsson, Karin; Calounova, Gabriela; Hjelm, Fredrik; Kriz, Vitezslav et al.

Part of BMC Immunology, p. 3, 2011

• DOI for Shb deficient mice display an augmented T_H2 response in peripheral CD4+ T cells
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The Src homology 2 domain-containing adapter protein B (SHB) regulates mouse oocyte maturation

Calounova, Gabriela; Livera, Gabriel; Zhang, X-Q; Liu, Kui et al.

Part of PLOS ONE, 2010

• DOI for The Src homology 2 domain-containing adapter protein B (SHB) regulates mouse oocyte maturation

Dysfunctional microvasculature as a consequence of shb gene inactivation causes impaired tumor growth

Funa, Nina S; Kriz, Vitezslav; Zang, Guangxiang; Calounova, Gabriela et al.

Part of Cancer Research, p. 2141-2148, 2009

• DOI for Dysfunctional microvasculature as a consequence of shb gene inactivation causes impaired tumor growth

Impaired glucose homeostasis in Shb-/- mice

Åkerblom, Björn; Barg, Sebastian; Calounova, Gabriela; Mokhtari, Dariush et al.

Part of Journal of Endocrinology, p. 271-279, 2009

• DOI for Impaired glucose homeostasis in Shb-/- mice

Increased Hsp70 expression attenuates cytokine-induced cell death in islets of Langerhans from Shb knockout mice

Mokhtari, Dariush; Åkerblom, Björn; Mehmeti, Ilir; Wang, Xuan et al.

Part of Biochemical and Biophysical Research Communications - BBRC, p. 553-557, 2009

• DOI for Increased Hsp70 expression attenuates cytokine-induced cell death in islets of Langerhans from Shb knockout mice

Interdependent fibroblast growth factor and activin A signaling promotes the expression of endodermal genes in differentiating mouse embryonic stem cells expressing Src Homology 2-domain inactive Shb

Funa, Nina; Saldeen, Johan; Åkerblom, Björn; Welsh, Michael

Part of Differentiation, p. 443-453, 2008

• DOI for Interdependent fibroblast growth factor and activin A signaling promotes the expression of endodermal genes in differentiating mouse embryonic stem cells expressing Src Homology 2-domain inactive Shb

Shb gene knockdown increases the susceptibility of SVR endothelial tumor cells to apoptotic stimuli in vitro and in vivo

Funa, Nina; Reddy, Kalpana; Bhandarkar, Sulochana; Kurenova, Elena et al.

Part of Journal of Investigative Dermatology, p. 710-716, 2008

• DOI for Shb gene knockdown increases the susceptibility of SVR endothelial tumor cells to apoptotic stimuli in vitro and in vivo

Reduced tumor growth in vivo and increased c-Abl activity in PC3 prostate cancer cells overexpressing the Shb adapter protein

Davoodpour, Padideh; Landström, Maréne; Welsh, Michael

Part of BMC Cancer, p. 161, 2007

• DOI for Reduced tumor growth in vivo and increased c-Abl activity in PC3 prostate cancer cells overexpressing the Shb adapter protein

Shb null allele is inherited with a transmission ratio distortion and causes reduced viability in utero

Kriz, Vitezslav; Mares, Jaroslav; Wentzel, Parri; Funa, Nina S. et al.

Part of Developmental Dynamics, p. 2485-2492, 2007

• DOI for Shb null allele is inherited with a transmission ratio distortion and causes reduced viability in utero

Claes Hellerström: a friendly islet explorer

Andersson, Arne; Eriksson, Ulf J.; Jansson, Leif; Sandler, Stellan et al.

Part of Diabetologia, 2007

Glucose intolerance and reduced islet blood flow in transgenic mice expressing the FRK tyrosine kinase under the control of the rat insulin promoter

Annerén, Cecilia; Welsh, Michael; Jansson, Leif

Part of American Journal of Physiology. Endocrinology and Metabolism, 2007

• DOI for Glucose intolerance and reduced islet blood flow in transgenic mice expressing the FRK tyrosine kinase under the control of the rat insulin promoter

A role of FRK in regulation of embryonal pancreatic beta cell formation

Åkerblom, Björn; Annerén, Cecilia; Welsh, Michael

Part of Molecular and Cellular Endocrinology, p. 73-78, 2007

• DOI for A role of FRK in regulation of embryonal pancreatic beta cell formation

Consequences of Shb and c-Abl interactions for cell death in response to various stress stimuli

Hägerkvist, Robert; Mokhtari, Dariush; Lindholm, Cecilia; Farnebo, Filip et al.

Part of Experimental Cell Research, p. 284-291, 2007

• DOI for Consequences of Shb and c-Abl interactions for cell death in response to various stress stimuli

Platelet-derived growth factor receptor-beta promotes early endothelial cell differentiation

Rolny, Charlotte; Nilsson, Ingrid; Magnusson, Peetra; Armulik, Annika et al.

Part of Blood, p. 1877-1886, 2006

• DOI for Platelet-derived growth factor receptor-beta promotes early endothelial cell differentiation

The SHB adapter protein is required for normal maturation of mesoderm during in vitro differentiation of embryonic stem cells

Kriz, Vitezslav; Ågren, Nina; Lindholm, Cecilia; Lenell, Samuel et al.

Part of Journal of Biological Chemistry, p. 34484-34491, 2006

• DOI for The SHB adapter protein is required for normal maturation of mesoderm during in vitro differentiation of embryonic stem cells

A perfusion protocol for highly efficient transduction of intact pancreatic islets of Langerhans

Barbu, Andreea R.; Bodin, Birgitta; Welsh, Michael; Jansson, Leif et al.

Part of Diabetologia, p. 2388-2391, 2006

• DOI for A perfusion protocol for highly efficient transduction of intact pancreatic islets of Langerhans

SHB and angiogenic factors promote ES cell differentiation to insulin-producing cells.

Saldeen, Johan; Kriz, Vitezslav; Agren, Nina; Welsh, Michael

Part of Biochem Biophys Res Commun, p. 517-24, 2006

Shb promotes blood vessel formation in embryoid bodies by augmenting vascular endothelial growth factor receptor-2 and platelet-derived growth factor receptor-beta signaling

Rolny, Charlotte; Lu, Lingge; Ågren, Nina; Nilsson, Ingrid et al.

Part of Experimental Cell Research, p. 381-393, 2005

• DOI for Shb promotes blood vessel formation in embryoid bodies by augmenting vascular endothelial growth factor receptor-2 and platelet-derived growth factor receptor-beta signaling

A role of the protein Cbl in FGF-2-induced angiogenesis in murine brain endothelial cells

Holmqvist, Kristina; Welsh, Michael; Lu, Lingge

Part of Cellular Signalling, p. 1433-1438, 2005

• DOI for A role of the protein Cbl in FGF-2-induced angiogenesis in murine brain endothelial cells

The tyrosine kinase FRK/RAK participates in cytokine-induced islet cell cytotoxicity

Welsh, Michael; Welsh, Charlotte; Ekman, Maria; Dixelius, Johan et al.

Part of Biochemical Journal, p. 261-268, 2004

• DOI for The tyrosine kinase FRK/RAK participates in cytokine-induced islet cell cytotoxicity

The adaptor protein Shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration.

Holmqvist, Kristina; Cross, Michael J; Rolny, Charlotte; Hägerkvist, Robert et al.

Part of J Biological chemistry, p. 22267-22275, 2004

The FRK/RAK-SHB signaling cascade: a versatile signal-transduction pathway that regulates cell survival, differentiation and profileration

Annerén, Cecilia; Lindholm, Cecilia K.; Kriz, Vitezslav; Welsh, Michael

Part of Current molecular medicine, p. 313-324, 2003

The SHB protein is required for efficient multilineage differentiation of mouse embryonic stem cells

Kriz, Vitezslav; Anneren, Cecilia; Lai, Cheng; Karlsson, Jacob et al.

Part of Exp Cell Res, p. 40-56, 2003

The Shb adaptor protein causes Src-dependent cell spreading and activation of focal adhesion kinase in murine brain endothelial cells

Holmqvist, Kristina; Cross, Michael; Riley, Debbie; Welsh, Michael

Part of Cell Signal, p. 171-179, 2003

GTK Tyrosine Kinase-induced Alteration of IRS-protein Signalling in Insulin Producing Cells

Annerén, Cecilia; Welsh, Michael

Part of Molecular Medicine, p. 705-713, 2002

The Shb Adaptor Protein Binds to Tyrosine 766 in the FGFR-1 and Regulatesthe Ras/MEK/MAPK Pathway via FRS2 Phosphorylation in Endothelial Cells

Cross, Michael J; Lu, Lingge; Magnusson, Peetra; Nyqvist, Daniel et al.

Part of Molecular Biology of the Cell, p. 2881-2893, 2002

• DOI for The Shb Adaptor Protein Binds to Tyrosine 766 in the FGFR-1 and Regulatesthe Ras/MEK/MAPK Pathway via FRS2 Phosphorylation in Endothelial Cells

Overexpression of the Shb SH2 domain-protein in insulin-producing cells leads to altered signaling through the IRS-1 and IRS-2 proteins

Welsh, Nils; Makeeva, Natalia; Welsh, Michael

Part of Molecular Medicine, p. 695-704, 2002

Shb links SLP-76 and Vav with the CD3 complex in Jurkat T cells

Lindholm, Cecilia K; Henriksson, Maria L; Hallberg, Bengt; Welsh, Michael

Part of European Journal of Biochemistry, p. 3279-3288, 2002

• DOI for Shb links SLP-76 and Vav with the CD3 complex in Jurkat T cells

Role of the Src Homology 2 domain-containing protein Shb in murine brain endothelial cell proliferation and differentiation

Lu, Lingge; Holmqvist, Kristina; Cross, Michael; Welsh, Michael

Part of Cell Growth Differ, p. 141-148, 2002

Increased cytokine-induced cytotoxicity of pancreatic islet cells from transgenic mice expressing the Src-like tyrosine kinase GTK

Annerén, Cecilia; Welsh, M

Part of Mol Med., p. 301-310, 2001

Endostatin-induced tyrosine kinase signaling through the Shb adaptor protein regulates endothelial cell apoptosis

Dixelius, Johan; Larsson, Helena; Sasaki, Takako; Holmqvist, Kristina et al.

Part of Blood, p. 3403-3411, 2000

Shf, a Shb-like Adapter protein, Is Involved in PDGF-a-receptor Regulation of Apoptosis

Lindholm, Cecilia K; Frantz, Daniel J; Shoelson, Steven E; Welsh, Michael

Part of Biochemical and Biophysical Research Communications - BBRC, p. 537-543, 2000

• DOI for Shf, a Shb-like Adapter protein, Is Involved in PDGF-a-receptor Regulation of Apoptosis

Role of the Bsk/lyk non-receptor tyrosine kinase for the control of growth and hormone production in RINm5F cells

Annerén, Cecilia; Welsh, Michael

Part of Growth Factors, p. 233-247, 2000

Platelet-Derived Growth Factor-Mediated Signaling through the Shb Adaptor Protein: Effects on Cytoskeletal Organization

Hooshmand-Rad, Roya; Lu, Lingge; Heldin, Carl-Henrik; Claesson-Welsh, Lena et al.

Part of Experimental Cell Research, p. 245-254, 2000

• DOI for Platelet-Derived Growth Factor-Mediated Signaling through the Shb Adaptor Protein: Effects on Cytoskeletal Organization

Role of tyrosine kinase signaling for b-cell replication and survival

Welsh, Michael; Annerén, Cecilia; Lindholm, Cecilia; Kriz, Vitezslav et al.

Part of Upsala Journal of Medical Sciences, Supplement, p. 7-15, 2000

GTK, a Src-related tyrosine kinase, induces nerve growth factor-independent neurite outgrowth in PC12 cells through activation of the Rap1 pathway: Relationship to Shb tyrosine phosphorylation and elevated levels of focal adhesion kinase

Annerén, Cecilia; Reedquist, K A; Bos, J L; Welsh, M

Part of J Biol Chem, p. 29153-29161, 2000

NGF-dependent neurite outgrowth in PC12 cells overexpressing the Src homology 2-domain protein Shb requires activation of the Rap1 pathway

Lu, Lingge; Anneren, Cecilia; Reedquist, Kris A.; Bos, Johannes L. et al.

Part of Exp. Cell Res., p. 370-377, 2000

Requirement of the Src homology 2 domain protein Shb for T cell receptor-dependent activation of the Interleukin-2 gene nuclear factor for activation of T cells element in Jurkat T cells

Lindholm, Cecilia K; Gylfe, Erik; Zhang, Weigu; Samelson, Lawrence E et al.

Part of Journal of Biological Chemistry, p. 28050-28057, 1999

• DOI for Requirement of the Src homology 2 domain protein Shb for T cell receptor-dependent activation of the Interleukin-2 gene nuclear factor for activation of T cells element in Jurkat T cells

Transgeneic mice expressing the Shb adaptor protein under the control of  rat insulin promoter exhibit altered viability of pancreatic islet cells

Welsh, Michael; Christmansson, L; Karlsson, T; Sandler, Stellan et al.

Part of Molecular Medicine, p. 169-180, 1999

Mutation of C-terminal tyrosine residues Y497/Y504 of the Src-family member Bsk/Iyk decreases NIH3T3 cell proliferation

Öberg-Welsh, Charlotte; Annerén, Cecilia; Welsh, Michael

Part of Growth Factors, p. 111-124, 1998

The Src homology 2 domain protein shb transmits basic fibroblast growth factor - and nerve growth factor - dependent differentiation signals in PC12 cells1

Karlsson, Torbjörn; Kullander, Klas; Welsh, Michael

Part of Cell growth & differentiation, p. 757-766, 1998

Stimulation through the T cell receptor leads to interactions between SHB and several signaling proteins

Welsh, Michael; Songyang, Zhou; Frantz, J Daniel; Trub, Thomas et al.

Part of Oncogene, p. 891-901, 1998

Angiostatin induces endothelial cell apoptosis and activation of focal adhesion kinase independently of the integrin-binding motif RGD

Claesson-Welsh, Lena; Welsh, Michael; Ito, Nobuyuki; Anand-Apte, Bela et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 5579-5583, 1998

Effects of vascular endothelial growth factor on pancreatic duct cell replication and the insulin production of fetal islet-like cell clusters in vitro

Öberg-Welsh, Charlotte; Sandler, Stellan; Andersson, Arne; Welsh, Michael

Part of Molecular and Cellular Endocrinology, p. 125-132, 1997

• DOI for Effects of vascular endothelial growth factor on pancreatic duct cell replication and the insulin production of fetal islet-like cell clusters in vitro

Modulation of Src homology 3 proteins by the proline-rich adaptor protein Shb

Karlsson, Torbjörn; Welsh, Michael

Part of Experimental Cell Research, p. 269-275, 1997

• DOI for Modulation of Src homology 3 proteins by the proline-rich adaptor protein Shb

Effects of certain growth factors on in vitro maturation of rat fetal islet-like structures.

Oberg-Welsh, C; Welsh, M

Part of Pancreas, p. 334-9, 1996

Control of SHB gene expression by protein phosphorylation

Lavergne, Corinne; Mares, Jaroslav; Karlsson, Torbjörn; Breant, Bernadette et al.

Part of Cellular Signalling, p. 55-58, 1996

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Apoptosis of NIH3T3 cells overexpressing the Src homology 2 domain protein Shb

Karlsson, Torbjörn; Welsh, Michael

Part of Oncogene, p. 955-961, 1996

Cloning of BSK, a murine FRK homologue with a specific pattern of tissue distribution.

Oberg-Welsh, C; Welsh, M

Part of Gene, p. 239-42, 1995

Molecular interactions of the Src homology 2 domain protein Shb with phosphotyrosine residues, tyrosine kinase receptors and Src homology 3 domain proteins

Karlsson, Torbjörn; Songyang, Z; Landgren, E; Lavergne, C et al.

Part of Oncogene, p. 1475-1483, 1995

Shb is a ubiquitously expressed Src homology 2 protein.

Welsh, M; Mares, J; Karlsson, T; Lavergne, C et al.

Part of Oncogene, p. 19-27, 1994

Expression of protein tyrosine kinases in islet cells: possible role of the Flk-1 receptor for beta-cell maturation from duct cells.

Oberg, C; Waltenberger, J; Claesson-Welsh, L; Welsh, M

Part of Growth Factors, p. 115-26, 1994

Perspectives on Vascular Regulation of Mechanisms Controlling Selective Immune Cell Function in the Tumor Immune Response

Welsh, Michael

Part of International Journal of Molecular Sciences, 2022

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The role of the Src Homology-2 domain containing protein B (SHB) in β cells

Welsh, Michael; Jamalpour, Maria; Zang, Guangxiang; Åkerblom, Björn

Part of Journal of Molecular Endocrinology, 2015

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VEGFA and tumour angiogenesis

Claesson-Welsh, Lena; Welsh, Michael

Part of Journal of Internal Medicine, p. 114-127, 2013

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The platelet-derived growth factor (PDGF) family of tyrosine kinase receptors: a Kit to fix the beta cell?

Welsh, Michael

Part of Diabetologia, p. 2092-2095, 2012

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The role of PDGFRβ macrophages and macrophage-derived IGF-1 in breast tumor growth in mice

Amoedo-Leite, Catarina; Testini, Chiara; Malaquias, Marta; Welsh, Michael et al.