Michael Welsh

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

He, Liqun; Testini, Chiara; Hekmati, Neda; Bonello, Altea et al.

Ingår i Molecular Oncology, 2025

• DOI för Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity
• Ladda ner fulltext (pdf) av Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis

Jin, Yi; Ding, Yindi; Richards, Mark; Kaakinen, Mika et al.

Ingår i Nature Cardiovascular Research, s. 1156-1173, 2022

• DOI för Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis
• Ladda ner fulltext (pdf) av Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis

The retirement of Editor-in-Chief Arne Andersson, Upsala Journal of Medical Sciences 2006–2022: an amazing journey under Arne's stewardship

Wikström, Gerhard; Welsh, Michael

Ingår i Upsala Journal of Medical Sciences, 2022

• DOI för The retirement of Editor-in-Chief Arne Andersson, Upsala Journal of Medical Sciences 2006–2022: an amazing journey under Arne's stewardship
• Ladda ner fulltext (pdf) av The retirement of Editor-in-Chief Arne Andersson, Upsala Journal of Medical Sciences 2006–2022: an amazing journey under Arne's stewardship

Perspectives on Vascular Regulation of Mechanisms Controlling Selective Immune Cell Function in the Tumor Immune Response

Welsh, Michael

Ingår i International Journal of Molecular Sciences, 2022

• DOI för Perspectives on Vascular Regulation of Mechanisms Controlling Selective Immune Cell Function in the Tumor Immune Response
• Ladda ner fulltext (pdf) av Perspectives on Vascular Regulation of Mechanisms Controlling Selective Immune Cell Function in the Tumor Immune Response

Mouse Breast Carcinoma Monocytic/Macrophagic Myeloid-Derived Suppressor Cell Infiltration as a Consequence of Endothelial Dysfunction in Shb-Deficient Endothelial Cells Increases Tumor Lung Metastasis

He, Qi; Jamalpour, Maria; Bergquist, Eric; Anderson, Robin et al.

Ingår i International Journal of Molecular Sciences, 2021

• DOI för Mouse Breast Carcinoma Monocytic/Macrophagic Myeloid-Derived Suppressor Cell Infiltration as a Consequence of Endothelial Dysfunction in Shb-Deficient Endothelial Cells Increases Tumor Lung Metastasis
• Ladda ner fulltext (pdf) av Mouse Breast Carcinoma Monocytic/Macrophagic Myeloid-Derived Suppressor Cell Infiltration as a Consequence of Endothelial Dysfunction in Shb-Deficient Endothelial Cells Increases Tumor Lung Metastasis

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

He, Liqun; Testini, Chiara; Hekmati, Neda; Bonello, Altea et al.

Ingår i Molecular Oncology, 2025

• DOI för Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity
• Ladda ner fulltext (pdf) av Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis

Jin, Yi; Ding, Yindi; Richards, Mark; Kaakinen, Mika et al.

Ingår i Nature Cardiovascular Research, s. 1156-1173, 2022

• DOI för Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis
• Ladda ner fulltext (pdf) av Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis

The retirement of Editor-in-Chief Arne Andersson, Upsala Journal of Medical Sciences 2006–2022: an amazing journey under Arne's stewardship

Wikström, Gerhard; Welsh, Michael

Ingår i Upsala Journal of Medical Sciences, 2022

• DOI för The retirement of Editor-in-Chief Arne Andersson, Upsala Journal of Medical Sciences 2006–2022: an amazing journey under Arne's stewardship
• Ladda ner fulltext (pdf) av The retirement of Editor-in-Chief Arne Andersson, Upsala Journal of Medical Sciences 2006–2022: an amazing journey under Arne's stewardship

Mouse Breast Carcinoma Monocytic/Macrophagic Myeloid-Derived Suppressor Cell Infiltration as a Consequence of Endothelial Dysfunction in Shb-Deficient Endothelial Cells Increases Tumor Lung Metastasis

He, Qi; Jamalpour, Maria; Bergquist, Eric; Anderson, Robin et al.

Ingår i International Journal of Molecular Sciences, 2021

• DOI för Mouse Breast Carcinoma Monocytic/Macrophagic Myeloid-Derived Suppressor Cell Infiltration as a Consequence of Endothelial Dysfunction in Shb-Deficient Endothelial Cells Increases Tumor Lung Metastasis
• Ladda ner fulltext (pdf) av Mouse Breast Carcinoma Monocytic/Macrophagic Myeloid-Derived Suppressor Cell Infiltration as a Consequence of Endothelial Dysfunction in Shb-Deficient Endothelial Cells Increases Tumor Lung Metastasis

The Felicitous Success of the Subsection Molecular Oncology of International Journal of Molecular Sciences

Welsh, Michael

Ingår i International Journal of Molecular Sciences, 2021

• DOI för The Felicitous Success of the Subsection Molecular Oncology of International Journal of Molecular Sciences
• Ladda ner fulltext (pdf) av The Felicitous Success of the Subsection Molecular Oncology of International Journal of Molecular Sciences

Pericyte dysfunction due to Shb gene deficiency increases B16F10 melanoma lung metastasis

He, Qi; Li, Xiujuan; He, Liqun; Li, Yousheng et al.

Ingår i International Journal of Cancer, s. 2634-2644, 2020

• DOI för Pericyte dysfunction due to Shb gene deficiency increases B16F10 melanoma lung metastasis
• Ladda ner fulltext (pdf) av Pericyte dysfunction due to Shb gene deficiency increases B16F10 melanoma lung metastasis

Absence of the Shb gene in mixed-lineage leukemia MLL-AF9 cells increases latency in mice despite higher proliferation rates in vitro

Jamalpour, Maria; Bergquist, Eric; Welsh, Michael

Ingår i Experimental Cell Research, 2020

• DOI för Absence of the Shb gene in mixed-lineage leukemia MLL-AF9 cells increases latency in mice despite higher proliferation rates in vitro
• Ladda ner fulltext (pdf) av Absence of the Shb gene in mixed-lineage leukemia MLL-AF9 cells increases latency in mice despite higher proliferation rates in vitro

The Cdh5-CreERT2 transgene causes conditional Shb gene deletion in hematopoietic cells with consequences for immune cell responses to tumors

He, Qi; Li, Xiujuan; Singh, Kailash; Luo, Zhengkang et al.

Ingår i Scientific Reports, 2019

• DOI för The Cdh5-CreERT2 transgene causes conditional Shb gene deletion in hematopoietic cells with consequences for immune cell responses to tumors
• Ladda ner fulltext 1 (pdf) av The Cdh5-CreERT2 transgene causes conditional Shb gene deletion in hematopoietic cells with consequences for immune cell responses to tumors
• Ladda ner fulltext 2 (pdf) av The Cdh5-CreERT2 transgene causes conditional Shb gene deletion in hematopoietic cells with consequences for immune cell responses to tumors

Temporal Dynamics of VEGFA-Induced VEGFR2/FAK Co-Localization Depend on SHB

Pietilä, Ilkka; van Mourik, Djenolan; Tamelander, Andreas; Kriz, Vitezslav et al.

Ingår i Cells, 2019

• DOI för Temporal Dynamics of VEGFA-Induced VEGFR2/FAK Co-Localization Depend on SHB
• Ladda ner fulltext (pdf) av Temporal Dynamics of VEGFA-Induced VEGFR2/FAK Co-Localization Depend on SHB

Pro-tumoral immune cell alterations in wild type and Shb-deficient mice in response to 4T1 breast carcinomas

Li, Xiujuan; Singh, Kailash; Luo, Zhengkang; Mejia Cordova, Mariela et al.

Ingår i Oncotarget, s. 18720-18733, 2018

• DOI för Pro-tumoral immune cell alterations in wild type and Shb-deficient mice in response to 4T1 breast carcinomas
• Ladda ner fulltext (pdf) av Pro-tumoral immune cell alterations in wild type and Shb-deficient mice in response to 4T1 breast carcinomas

Leukocyte differentiation by histidine-rich glycoprotein/stanniocalcin-2 complex regulates murine glioma growth through modulation of anti-tumor immunity

Roche, Francis P.; Pietilä, Ilkka; Kaito, Hiroshi; Sjöström, Elisabet O. et al.

Ingår i Molecular Cancer Therapeutics, s. 1961-1972, 2018

• DOI för Leukocyte differentiation by histidine-rich glycoprotein/stanniocalcin-2 complex regulates murine glioma growth through modulation of anti-tumor immunity
• Ladda ner fulltext (pdf) av Leukocyte differentiation by histidine-rich glycoprotein/stanniocalcin-2 complex regulates murine glioma growth through modulation of anti-tumor immunity

Disparate effects of Shb-gene deficiency on disease characteristics in murine models of myeloid, B-cell and T-cell leukemia

Jamalpour, Maria; Li, Xiujuan; Gustafsson, Karin; Tyner, Jeffrey et al.

Ingår i Tumor Biology, s. 1-13, 2018

• DOI för Disparate effects of Shb-gene deficiency on disease characteristics in murine models of myeloid, B-cell and T-cell leukemia
• Ladda ner fulltext 1 (pdf) av Disparate effects of Shb-gene deficiency on disease characteristics in murine models of myeloid, B-cell and T-cell leukemia
• Ladda ner fulltext 2 (pdf) av Disparate effects of Shb-gene deficiency on disease characteristics in murine models of myeloid, B-cell and T-cell leukemia

Tumor SHB gene expression affects disease characteristics in human acute myeloid leukemia

Jamalpour, Maria; Li, Xiujuan; Cavelier, Lucia; Gustafsson, Karin et al.

Ingår i Tumor Biology, 2017

• DOI för Tumor SHB gene expression affects disease characteristics in human acute myeloid leukemia
• Ladda ner fulltext (pdf) av Tumor SHB gene expression affects disease characteristics in human acute myeloid leukemia

Claes Hellerström and Cartesian Diver respirometry

Welsh, Michael

Ingår i Upsala Journal of Medical Sciences, s. 77-80, 2016

• DOI för Claes Hellerström and Cartesian Diver respirometry

Maintenance of hematopoietic stem cell dormancy: yet another role for the macrophage

Gustafsson, Karin; Welsh, Michael

Ingår i stem cell investigation, 2016

• DOI för Maintenance of hematopoietic stem cell dormancy: yet another role for the macrophage

Identification and characterization of VEGF-A-responsive neutrophils expressing CD49d, VEGFR1, and CXCR4 in mice and humans

Massena, Sara; Christoffersson, Gustaf; Vågesjö, Evelina; Seignez, Cédric et al.

Ingår i Blood, s. 2016-2026, 2015

• DOI för Identification and characterization of VEGF-A-responsive neutrophils expressing CD49d, VEGFR1, and CXCR4 in mice and humans

Shb deficiency in endothelium but not in leukocytes is responsible for impaired vascular performance during hindlimb ischemia.

Nikpour, Maryam; Gustafsson, Karin; Vågesjö, Evelina; Seignez, Cedric et al.

Ingår i Acta Physiologica, s. 200-209, 2015

• DOI för Shb deficiency in endothelium but not in leukocytes is responsible for impaired vascular performance during hindlimb ischemia.
• Ladda ner fulltext (pdf) av Shb deficiency in endothelium but not in leukocytes is responsible for impaired vascular performance during hindlimb ischemia.

Vascular dysfunction and increased metastasis of B16F10 melanomas in Shb deficient mice as compared with their wild type counterparts

Zang, Guangxiang; Gustafsson, Karin; Jamalpour, Maria; Hong, Jongwook et al.

Ingår i BMC Cancer, 2015

• DOI för Vascular dysfunction and increased metastasis of B16F10 melanomas in Shb deficient mice as compared with their wild type counterparts
• Ladda ner fulltext (pdf) av Vascular dysfunction and increased metastasis of B16F10 melanomas in Shb deficient mice as compared with their wild type counterparts

The Src homology-2 protein Shb modulates focal adhesion kinase signaling in a BCR-ABL myeloproliferative disorder causing accelerated progression of disease

Gustafsson, Karin; Jamalpour, Maria; Trinh, Camilla; Kharas, Michael G et al.

Ingår i Journal of Hematology & Oncology, s. 45, 2014

• DOI för The Src homology-2 protein Shb modulates focal adhesion kinase signaling in a BCR-ABL myeloproliferative disorder causing accelerated progression of disease
• Ladda ner fulltext (pdf) av The Src homology-2 protein Shb modulates focal adhesion kinase signaling in a BCR-ABL myeloproliferative disorder causing accelerated progression of disease

Absence of the adaptor protein Shb potentiates the T_H2 response in a mouse model of atopic dermatitis

Gustafsson, Karin; Willebrand, Elsa; Welsh, Michael

Ingår i Immunology, s. 33-41, 2014

• DOI för Absence of the adaptor protein Shb potentiates the T_H2 response in a mouse model of atopic dermatitis
• Ladda ner fulltext (pdf) av Absence of the adaptor protein Shb potentiates the T_H2 response in a mouse model of atopic dermatitis

Absence of Shb impairs insulin secretion by elevated FAK activity in pancreatic islets

Alenkvist, Ida; Dyachok, Oleg; Tian, Geng; Li, Jia et al.

Ingår i Journal of Endocrinology, s. 267-275, 2014

• DOI för Absence of Shb impairs insulin secretion by elevated FAK activity in pancreatic islets
• Ladda ner fulltext (pdf) av Absence of Shb impairs insulin secretion by elevated FAK activity in pancreatic islets

Role of Src homology 2 domain-containing protein B in the regulation of GFR and renal afferent arteriole responsiveness

Gao, Xiang; Sallstrom, Johan; Ma, Zufu; Welsh, Michael et al.

Ingår i The FASEB Journal, 2014

Absence of the Shb adaptor protein accelerates leukemia progression by control of cytokine responses

Gustafsson, Karin; Jamalpour, Maria; Welsh, Michael

Ingår i Experimental Hematology, 2013

The Src Homology 2 Protein Shb Promotes Cell Cycle Progression In Murine Hematopoietic Stem Cells By Regulation Of Focal Adhesion Kinase Activity

Gustafsson, Karin; Heffner, Garrett; Wenzel, Pamela L.; Curran, Matthew et al.

Ingår i Experimental Cell Research, s. 1852-1864, 2013

• DOI för The Src Homology 2 Protein Shb Promotes Cell Cycle Progression In Murine Hematopoietic Stem Cells By Regulation Of Focal Adhesion Kinase Activity
• Ladda ner fulltext (pdf) av The Src Homology 2 Protein Shb Promotes Cell Cycle Progression In Murine Hematopoietic Stem Cells By Regulation Of Focal Adhesion Kinase Activity

Aberrant association between vascular endothelial growth factor receptor-2 and VE-cadherin in response to vascular endothelial growth factor-a in Shb-deficient lung endothelial cells

Zang, Guangxiang; Christoffersson, Gustaf; Tian, Geng; Harun-Or-Rashid, Mohammad et al.

Ingår i Cellular Signalling, s. 85-92, 2013

• DOI för Aberrant association between vascular endothelial growth factor receptor-2 and VE-cadherin in response to vascular endothelial growth factor-a in Shb-deficient lung endothelial cells
• Ladda ner fulltext (pdf) av Aberrant association between vascular endothelial growth factor receptor-2 and VE-cadherin in response to vascular endothelial growth factor-a in Shb-deficient lung endothelial cells

The mechanisms of VEGF-A-induced recruitment of pro-angiogenic neutrophils

Massena, Sara; Christoffersson, Gustaf; Vågesjö, Evelina; Gustafsson, Karin et al.

Ingår i European Journal of Clinical Investigation, s. 27-27, 2013

SHB deficient mice display an increased GFR and augmented renal arteriolar contractions to both Adenosine and Ang II

Gao, Xiang; Sallstrom, Johan; Ma, Zufu; Welsh, Michael et al.

Ingår i The FASEB Journal, s. 909.14, 2013

Heterogeneity among RIP-Tag2 insulinomas allows vascular endothelial growth factor-A independent tumor expansion as revealed by studies in Shb mutant mice: implications for tumor angiogenesis

Åkerblom, Björn; Zang, Guangxiang; Zhuang, Zhen W.; Calounova, Gabriela et al.

Ingår i Molecular Oncology, s. 333-346, 2012

• DOI för Heterogeneity among RIP-Tag2 insulinomas allows vascular endothelial growth factor-A independent tumor expansion as revealed by studies in Shb mutant mice: implications for tumor angiogenesis
• Ladda ner fulltext (pdf) av Heterogeneity among RIP-Tag2 insulinomas allows vascular endothelial growth factor-A independent tumor expansion as revealed by studies in Shb mutant mice: implications for tumor angiogenesis

Vascular adaptation to a dysfunctional endothelium as a consequence of Shb deficiency

Christoffersson, Gustav; Zang, Guangxiang; Zhuang, Zhen W.; Vågesjö, Evelina et al.

Ingår i Angiogenesis, s. 469-480, 2012

• DOI för Vascular adaptation to a dysfunctional endothelium as a consequence of Shb deficiency
• Ladda ner fulltext (pdf) av Vascular adaptation to a dysfunctional endothelium as a consequence of Shb deficiency

Shb deficient mice display an augmented T_H2 response in peripheral CD4+ T cells

Gustafsson, Karin; Calounova, Gabriela; Hjelm, Fredrik; Kriz, Vitezslav et al.

Ingår i BMC Immunology, s. 3, 2011

• DOI för Shb deficient mice display an augmented T_H2 response in peripheral CD4+ T cells
• Ladda ner fulltext (pdf) av Shb deficient mice display an augmented T_H2 response in peripheral CD4+ T cells

The Src homology 2 domain-containing adapter protein B (SHB) regulates mouse oocyte maturation

Calounova, Gabriela; Livera, Gabriel; Zhang, X-Q; Liu, Kui et al.

Ingår i PLOS ONE, 2010

• DOI för The Src homology 2 domain-containing adapter protein B (SHB) regulates mouse oocyte maturation

Dysfunctional microvasculature as a consequence of shb gene inactivation causes impaired tumor growth

Funa, Nina S; Kriz, Vitezslav; Zang, Guangxiang; Calounova, Gabriela et al.

Ingår i Cancer Research, s. 2141-2148, 2009

• DOI för Dysfunctional microvasculature as a consequence of shb gene inactivation causes impaired tumor growth

Impaired glucose homeostasis in Shb-/- mice

Åkerblom, Björn; Barg, Sebastian; Calounova, Gabriela; Mokhtari, Dariush et al.

Ingår i Journal of Endocrinology, s. 271-279, 2009

• DOI för Impaired glucose homeostasis in Shb-/- mice

Increased Hsp70 expression attenuates cytokine-induced cell death in islets of Langerhans from Shb knockout mice

Mokhtari, Dariush; Åkerblom, Björn; Mehmeti, Ilir; Wang, Xuan et al.

Ingår i Biochemical and Biophysical Research Communications - BBRC, s. 553-557, 2009

• DOI för Increased Hsp70 expression attenuates cytokine-induced cell death in islets of Langerhans from Shb knockout mice

Interdependent fibroblast growth factor and activin A signaling promotes the expression of endodermal genes in differentiating mouse embryonic stem cells expressing Src Homology 2-domain inactive Shb

Funa, Nina; Saldeen, Johan; Åkerblom, Björn; Welsh, Michael

Ingår i Differentiation, s. 443-453, 2008

• DOI för Interdependent fibroblast growth factor and activin A signaling promotes the expression of endodermal genes in differentiating mouse embryonic stem cells expressing Src Homology 2-domain inactive Shb

Shb gene knockdown increases the susceptibility of SVR endothelial tumor cells to apoptotic stimuli in vitro and in vivo

Funa, Nina; Reddy, Kalpana; Bhandarkar, Sulochana; Kurenova, Elena et al.

Ingår i Journal of Investigative Dermatology, s. 710-716, 2008

• DOI för Shb gene knockdown increases the susceptibility of SVR endothelial tumor cells to apoptotic stimuli in vitro and in vivo

Reduced tumor growth in vivo and increased c-Abl activity in PC3 prostate cancer cells overexpressing the Shb adapter protein

Davoodpour, Padideh; Landström, Maréne; Welsh, Michael

Ingår i BMC Cancer, s. 161, 2007

• DOI för Reduced tumor growth in vivo and increased c-Abl activity in PC3 prostate cancer cells overexpressing the Shb adapter protein

Shb null allele is inherited with a transmission ratio distortion and causes reduced viability in utero

Kriz, Vitezslav; Mares, Jaroslav; Wentzel, Parri; Funa, Nina S. et al.

Ingår i Developmental Dynamics, s. 2485-2492, 2007

• DOI för Shb null allele is inherited with a transmission ratio distortion and causes reduced viability in utero

Claes Hellerström: a friendly islet explorer

Andersson, Arne; Eriksson, Ulf J.; Jansson, Leif; Sandler, Stellan et al.

Ingår i Diabetologia, 2007

Glucose intolerance and reduced islet blood flow in transgenic mice expressing the FRK tyrosine kinase under the control of the rat insulin promoter

Annerén, Cecilia; Welsh, Michael; Jansson, Leif

Ingår i American Journal of Physiology. Endocrinology and Metabolism, 2007

• DOI för Glucose intolerance and reduced islet blood flow in transgenic mice expressing the FRK tyrosine kinase under the control of the rat insulin promoter

A role of FRK in regulation of embryonal pancreatic beta cell formation

Åkerblom, Björn; Annerén, Cecilia; Welsh, Michael

Ingår i Molecular and Cellular Endocrinology, s. 73-78, 2007

• DOI för A role of FRK in regulation of embryonal pancreatic beta cell formation

Consequences of Shb and c-Abl interactions for cell death in response to various stress stimuli

Hägerkvist, Robert; Mokhtari, Dariush; Lindholm, Cecilia; Farnebo, Filip et al.

Ingår i Experimental Cell Research, s. 284-291, 2007

• DOI för Consequences of Shb and c-Abl interactions for cell death in response to various stress stimuli

Platelet-derived growth factor receptor-beta promotes early endothelial cell differentiation

Rolny, Charlotte; Nilsson, Ingrid; Magnusson, Peetra; Armulik, Annika et al.

Ingår i Blood, s. 1877-1886, 2006

• DOI för Platelet-derived growth factor receptor-beta promotes early endothelial cell differentiation

The SHB adapter protein is required for normal maturation of mesoderm during in vitro differentiation of embryonic stem cells

Kriz, Vitezslav; Ågren, Nina; Lindholm, Cecilia; Lenell, Samuel et al.

Ingår i Journal of Biological Chemistry, s. 34484-34491, 2006

• DOI för The SHB adapter protein is required for normal maturation of mesoderm during in vitro differentiation of embryonic stem cells

A perfusion protocol for highly efficient transduction of intact pancreatic islets of Langerhans

Barbu, Andreea R.; Bodin, Birgitta; Welsh, Michael; Jansson, Leif et al.

Ingår i Diabetologia, s. 2388-2391, 2006

• DOI för A perfusion protocol for highly efficient transduction of intact pancreatic islets of Langerhans

SHB and angiogenic factors promote ES cell differentiation to insulin-producing cells.

Saldeen, Johan; Kriz, Vitezslav; Agren, Nina; Welsh, Michael

Ingår i Biochem Biophys Res Commun, s. 517-24, 2006

Shb promotes blood vessel formation in embryoid bodies by augmenting vascular endothelial growth factor receptor-2 and platelet-derived growth factor receptor-beta signaling

Rolny, Charlotte; Lu, Lingge; Ågren, Nina; Nilsson, Ingrid et al.

Ingår i Experimental Cell Research, s. 381-393, 2005

• DOI för Shb promotes blood vessel formation in embryoid bodies by augmenting vascular endothelial growth factor receptor-2 and platelet-derived growth factor receptor-beta signaling

A role of the protein Cbl in FGF-2-induced angiogenesis in murine brain endothelial cells

Holmqvist, Kristina; Welsh, Michael; Lu, Lingge

Ingår i Cellular Signalling, s. 1433-1438, 2005

• DOI för A role of the protein Cbl in FGF-2-induced angiogenesis in murine brain endothelial cells

The tyrosine kinase FRK/RAK participates in cytokine-induced islet cell cytotoxicity

Welsh, Michael; Welsh, Charlotte; Ekman, Maria; Dixelius, Johan et al.

Ingår i Biochemical Journal, s. 261-268, 2004

• DOI för The tyrosine kinase FRK/RAK participates in cytokine-induced islet cell cytotoxicity

The adaptor protein Shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration.

Holmqvist, Kristina; Cross, Michael J; Rolny, Charlotte; Hägerkvist, Robert et al.

Ingår i J Biological chemistry, s. 22267-22275, 2004

The FRK/RAK-SHB signaling cascade: a versatile signal-transduction pathway that regulates cell survival, differentiation and profileration

Annerén, Cecilia; Lindholm, Cecilia K.; Kriz, Vitezslav; Welsh, Michael

Ingår i Current molecular medicine, s. 313-324, 2003

The SHB protein is required for efficient multilineage differentiation of mouse embryonic stem cells

Kriz, Vitezslav; Anneren, Cecilia; Lai, Cheng; Karlsson, Jacob et al.

Ingår i Exp Cell Res, s. 40-56, 2003

The Shb adaptor protein causes Src-dependent cell spreading and activation of focal adhesion kinase in murine brain endothelial cells

Holmqvist, Kristina; Cross, Michael; Riley, Debbie; Welsh, Michael

Ingår i Cell Signal, s. 171-179, 2003

GTK Tyrosine Kinase-induced Alteration of IRS-protein Signalling in Insulin Producing Cells

Annerén, Cecilia; Welsh, Michael

Ingår i Molecular Medicine, s. 705-713, 2002

The Shb Adaptor Protein Binds to Tyrosine 766 in the FGFR-1 and Regulatesthe Ras/MEK/MAPK Pathway via FRS2 Phosphorylation in Endothelial Cells

Cross, Michael J; Lu, Lingge; Magnusson, Peetra; Nyqvist, Daniel et al.

Ingår i Molecular Biology of the Cell, s. 2881-2893, 2002

• DOI för The Shb Adaptor Protein Binds to Tyrosine 766 in the FGFR-1 and Regulatesthe Ras/MEK/MAPK Pathway via FRS2 Phosphorylation in Endothelial Cells

Overexpression of the Shb SH2 domain-protein in insulin-producing cells leads to altered signaling through the IRS-1 and IRS-2 proteins

Welsh, Nils; Makeeva, Natalia; Welsh, Michael

Ingår i Molecular Medicine, s. 695-704, 2002

Shb links SLP-76 and Vav with the CD3 complex in Jurkat T cells

Lindholm, Cecilia K; Henriksson, Maria L; Hallberg, Bengt; Welsh, Michael

Ingår i European Journal of Biochemistry, s. 3279-3288, 2002

• DOI för Shb links SLP-76 and Vav with the CD3 complex in Jurkat T cells

Role of the Src Homology 2 domain-containing protein Shb in murine brain endothelial cell proliferation and differentiation

Lu, Lingge; Holmqvist, Kristina; Cross, Michael; Welsh, Michael

Ingår i Cell Growth Differ, s. 141-148, 2002

Increased cytokine-induced cytotoxicity of pancreatic islet cells from transgenic mice expressing the Src-like tyrosine kinase GTK

Annerén, Cecilia; Welsh, M

Ingår i Mol Med., s. 301-310, 2001

Endostatin-induced tyrosine kinase signaling through the Shb adaptor protein regulates endothelial cell apoptosis

Dixelius, Johan; Larsson, Helena; Sasaki, Takako; Holmqvist, Kristina et al.

Ingår i Blood, s. 3403-3411, 2000

Shf, a Shb-like Adapter protein, Is Involved in PDGF-a-receptor Regulation of Apoptosis

Lindholm, Cecilia K; Frantz, Daniel J; Shoelson, Steven E; Welsh, Michael

Ingår i Biochemical and Biophysical Research Communications - BBRC, s. 537-543, 2000

• DOI för Shf, a Shb-like Adapter protein, Is Involved in PDGF-a-receptor Regulation of Apoptosis

Platelet-Derived Growth Factor-Mediated Signaling through the Shb Adaptor Protein: Effects on Cytoskeletal Organization

Hooshmand-Rad, Roya; Lu, Lingge; Heldin, Carl-Henrik; Claesson-Welsh, Lena et al.

Ingår i Experimental Cell Research, s. 245-254, 2000

• DOI för Platelet-Derived Growth Factor-Mediated Signaling through the Shb Adaptor Protein: Effects on Cytoskeletal Organization

Role of the Bsk/lyk non-receptor tyrosine kinase for the control of growth and hormone production in RINm5F cells

Annerén, Cecilia; Welsh, Michael

Ingår i Growth Factors, s. 233-247, 2000

Role of tyrosine kinase signaling for b-cell replication and survival

Welsh, Michael; Annerén, Cecilia; Lindholm, Cecilia; Kriz, Vitezslav et al.

Ingår i Upsala Journal of Medical Sciences, Supplement, s. 7-15, 2000

GTK, a Src-related tyrosine kinase, induces nerve growth factor-independent neurite outgrowth in PC12 cells through activation of the Rap1 pathway: Relationship to Shb tyrosine phosphorylation and elevated levels of focal adhesion kinase

Annerén, Cecilia; Reedquist, K A; Bos, J L; Welsh, M

Ingår i J Biol Chem, s. 29153-29161, 2000

NGF-dependent neurite outgrowth in PC12 cells overexpressing the Src homology 2-domain protein Shb requires activation of the Rap1 pathway

Lu, Lingge; Anneren, Cecilia; Reedquist, Kris A.; Bos, Johannes L. et al.

Ingår i Exp. Cell Res., s. 370-377, 2000

Requirement of the Src homology 2 domain protein Shb for T cell receptor-dependent activation of the Interleukin-2 gene nuclear factor for activation of T cells element in Jurkat T cells

Lindholm, Cecilia K; Gylfe, Erik; Zhang, Weigu; Samelson, Lawrence E et al.

Ingår i Journal of Biological Chemistry, s. 28050-28057, 1999

• DOI för Requirement of the Src homology 2 domain protein Shb for T cell receptor-dependent activation of the Interleukin-2 gene nuclear factor for activation of T cells element in Jurkat T cells

Transgeneic mice expressing the Shb adaptor protein under the control of  rat insulin promoter exhibit altered viability of pancreatic islet cells

Welsh, Michael; Christmansson, L; Karlsson, T; Sandler, Stellan et al.

Ingår i Molecular Medicine, s. 169-180, 1999

Mutation of C-terminal tyrosine residues Y497/Y504 of the Src-family member Bsk/Iyk decreases NIH3T3 cell proliferation

Öberg-Welsh, Charlotte; Annerén, Cecilia; Welsh, Michael

Ingår i Growth Factors, s. 111-124, 1998

The Src homology 2 domain protein shb transmits basic fibroblast growth factor - and nerve growth factor - dependent differentiation signals in PC12 cells1

Karlsson, Torbjörn; Kullander, Klas; Welsh, Michael

Ingår i Cell growth & differentiation, s. 757-766, 1998

Stimulation through the T cell receptor leads to interactions between SHB and several signaling proteins

Welsh, Michael; Songyang, Zhou; Frantz, J Daniel; Trub, Thomas et al.

Ingår i Oncogene, s. 891-901, 1998

Angiostatin induces endothelial cell apoptosis and activation of focal adhesion kinase independently of the integrin-binding motif RGD

Claesson-Welsh, Lena; Welsh, Michael; Ito, Nobuyuki; Anand-Apte, Bela et al.

Ingår i Proceedings of the National Academy of Sciences of the United States of America, s. 5579-5583, 1998

Effects of vascular endothelial growth factor on pancreatic duct cell replication and the insulin production of fetal islet-like cell clusters in vitro

Öberg-Welsh, Charlotte; Sandler, Stellan; Andersson, Arne; Welsh, Michael

Ingår i Molecular and Cellular Endocrinology, s. 125-132, 1997

• DOI för Effects of vascular endothelial growth factor on pancreatic duct cell replication and the insulin production of fetal islet-like cell clusters in vitro

Modulation of Src homology 3 proteins by the proline-rich adaptor protein Shb

Karlsson, Torbjörn; Welsh, Michael

Ingår i Experimental Cell Research, s. 269-275, 1997

• DOI för Modulation of Src homology 3 proteins by the proline-rich adaptor protein Shb

Effects of certain growth factors on in vitro maturation of rat fetal islet-like structures.

Oberg-Welsh, C; Welsh, M

Ingår i Pancreas, s. 334-9, 1996

Control of SHB gene expression by protein phosphorylation

Lavergne, Corinne; Mares, Jaroslav; Karlsson, Torbjörn; Breant, Bernadette et al.

Ingår i Cellular Signalling, s. 55-58, 1996

• DOI för Control of SHB gene expression by protein phosphorylation

Apoptosis of NIH3T3 cells overexpressing the Src homology 2 domain protein Shb

Karlsson, Torbjörn; Welsh, Michael

Ingår i Oncogene, s. 955-961, 1996

Cloning of BSK, a murine FRK homologue with a specific pattern of tissue distribution.

Oberg-Welsh, C; Welsh, M

Ingår i Gene, s. 239-42, 1995

Molecular interactions of the Src homology 2 domain protein Shb with phosphotyrosine residues, tyrosine kinase receptors and Src homology 3 domain proteins

Karlsson, Torbjörn; Songyang, Z; Landgren, E; Lavergne, C et al.

Ingår i Oncogene, s. 1475-1483, 1995

Shb is a ubiquitously expressed Src homology 2 protein.

Welsh, M; Mares, J; Karlsson, T; Lavergne, C et al.

Ingår i Oncogene, s. 19-27, 1994

Expression of protein tyrosine kinases in islet cells: possible role of the Flk-1 receptor for beta-cell maturation from duct cells.

Oberg, C; Waltenberger, J; Claesson-Welsh, L; Welsh, M

Ingår i Growth Factors, s. 115-26, 1994

Perspectives on Vascular Regulation of Mechanisms Controlling Selective Immune Cell Function in the Tumor Immune Response

Welsh, Michael

Ingår i International Journal of Molecular Sciences, 2022

• DOI för Perspectives on Vascular Regulation of Mechanisms Controlling Selective Immune Cell Function in the Tumor Immune Response
• Ladda ner fulltext (pdf) av Perspectives on Vascular Regulation of Mechanisms Controlling Selective Immune Cell Function in the Tumor Immune Response

The role of the Src Homology-2 domain containing protein B (SHB) in β cells

Welsh, Michael; Jamalpour, Maria; Zang, Guangxiang; Åkerblom, Björn

Ingår i Journal of Molecular Endocrinology, 2015

• DOI för The role of the Src Homology-2 domain containing protein B (SHB) in β cells
• Ladda ner fulltext (pdf) av The role of the Src Homology-2 domain containing protein B (SHB) in β cells

VEGFA and tumour angiogenesis

Claesson-Welsh, Lena; Welsh, Michael

Ingår i Journal of Internal Medicine, s. 114-127, 2013

• DOI för VEGFA and tumour angiogenesis
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The platelet-derived growth factor (PDGF) family of tyrosine kinase receptors: a Kit to fix the beta cell?

Welsh, Michael

Ingår i Diabetologia, s. 2092-2095, 2012

• DOI för The platelet-derived growth factor (PDGF) family of tyrosine kinase receptors: a Kit to fix the beta cell?
• Ladda ner fulltext (pdf) av The platelet-derived growth factor (PDGF) family of tyrosine kinase receptors: a Kit to fix the beta cell?

The role of PDGFRβ macrophages and macrophage-derived IGF-1 in breast tumor growth in mice

Amoedo-Leite, Catarina; Testini, Chiara; Malaquias, Marta; Welsh, Michael et al.