Anders Lewén
Consultant at Department of Medical Sciences; Neurosurgery
- Visiting address:
- Akademiska sjukhuset, ingång 85 2 tr
- Postal address:
- Akademiska sjukhuset, ing 85 2 tr
751 85 UPPSALA
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Publications
Selection of publications
- Positive correlation between occlusion rate and nidus size of proton beam treated brain arteriovenous malformations (AVMs) (2016)
- Promising clinical outcome of elderly with TBI after modern neurointensive care (2016)
- Updated periodic evaluation of standardized neurointensive care shows that it is possible to maintain a high level of favorable outcome even with increasing mean age (2015)
- Refined microdialysis method for protein biomarker sampling in acute brain injury in the neurointensive care setting (2014)
- Acute neurosurgery for traumatic brain injury by general surgeons in Swedish county hospitals (2014)
- Cerebral microdialysis for protein biomarker monitoring in the neurointensive care setting - a technical approach (2014)
- New Microdialysis Method for Protein Biomarker Sampling in the Neurointensive Care Setting (2014)
- Should the Neurointensive Care Management of Traumatic Brain Injury Patients be Individualized According to Autoregulation Status and Injury Subtype? (2014)
- Brain tissue oxygenation and cerebral metabolic patterns in focal and diffuse traumatic brain injury (2014)
- Outcome from spontaneous subarachnoid haemorrhage (2014)
- Monitoring of Cerebral Blood Flow and Metabolism Bedside in Patients with Subarachnoid Hemorrhage - A Xenon-CT and Microdialysis Study (2014)
- The Neurological Wake-up Test Does not Alter Cerebral Energy Metabolism and Oxygenation in Patients with Severe Traumatic Brain Injury (2014)
- Improved Microdialysis Sampling of Proteins using Surface Modified Catheters (2013)
- Traumatic axonal injury in the mouse is accompanied by a dynamic inflammatory response, astroglial reactivity and complex behavioral changes (2013)
- Introduction of the Uppsala Traumatic Brain Injury register for regular surveillance of patient characteristics and neurointensive care management including secondary insult quantification and clinical outcome (2013)
- Interstitial F2-Isoprostane 8-Iso-PGF2α As a Biomarker of Oxidative Stress after Severe Human Traumatic Brain Injury (2012)
- An evaluation of three measures of intracranial compliance in traumatic brain injury patients (2012)
- The use of nurse checklists in a bedside computer-based information system to focus on avoiding secondary insults in neurointensive care (2012)
- Brain Tissue Oxygenation and Cerebral Perfusion Pressure Thresholds of Ischemia in a Standardized Pig Brain Death Model (2012)
- The nitrone free radical scavenger NXY-059 is neuroprotective when administered after traumatic brain injury in the rat (2008)
- Oxygen free radical-dependent activation of extracellular signal-regulated kinase mediates apoptosis-like cell death after traumatic brain injury (2004)
Recent publications
- A mathematical model for temporal cerebral blood flow response to acetazolamide evaluated in patients with Moyamoya disease (2024)
- Absolute Contusion Expansion Is Superior to Relative Expansion in Predicting Traumatic Brain Injury Outcomes (2024)
- Cerebrovascular reactivity (PRx) and optimal cerebral perfusion pressure in elderly with traumatic brain injury (2024)
- Trends in incidence and treatments of spontaneous subarachnoid hemorrhage (2024)
- Autoregulatory Cerebral Perfusion Pressure Insults in Traumatic Brain Injury and Aneurysmal Subarachnoid Hemorrhage (2024)
All publications
Articles
- A mathematical model for temporal cerebral blood flow response to acetazolamide evaluated in patients with Moyamoya disease (2024)
- Absolute Contusion Expansion Is Superior to Relative Expansion in Predicting Traumatic Brain Injury Outcomes (2024)
- Cerebrovascular reactivity (PRx) and optimal cerebral perfusion pressure in elderly with traumatic brain injury (2024)
- Trends in incidence and treatments of spontaneous subarachnoid hemorrhage (2024)
- Autoregulatory Cerebral Perfusion Pressure Insults in Traumatic Brain Injury and Aneurysmal Subarachnoid Hemorrhage (2024)
- The effects of cerebral pressure autoregulation status and CPP levels on cerebral metabolism in pediatric traumatic brain injury (2024)
- Thiopental and decompressive craniectomy as last-tier ICP-treatments in aneurysmal subarachnoid hemorrhage (2023)
- A Dedicated 21-Plex Proximity Extension Assay Panel for High-Sensitivity Protein Biomarker Detection Using Microdialysis in Severe Traumatic Brain Injury (2023)
- Evaluation of single-delay arterial spin labeling-based spatial coefficient of variation and histogram-based parameters in relation to cerebrovascular reserve in patients with Moyamoya disease. (2023)
- Lumbar puncture-verified subarachnoid hemorrhage (2023)
- Antithrombotic agent usage before ictus in aneurysmal subarachnoid hemorrhage (2023)
- ASL-MRI-guided evaluation of multiple burr hole revascularization surgery in Moyamoya disease (2023)
- Intracranial Pressure Variability (2023)
- ICP, CPP, and PRx in traumatic brain injury and aneurysmal subarachnoid hemorrhage (2023)
- ICP, PRx, CPP, and ∆CPPopt in pediatric traumatic brain injury (2023)
- Higher Intracranial Pressure Variability is Associated with Lower Cerebrovascular Resistance in Aneurysmal Subarachnoid Hemorrhage (2023)
- Cerebral Microdialysis Monitoring of Energy Metabolism: Relation to Cerebral Blood Flow and Oxygen Delivery in Aneurysmal Subarachnoid Hemorrhage (2023)
- Editorial: Moyamoya disease - natural history and therapeutic challenges (2023)
- Intracranial lesion features in moderate-to-severe traumatic brain injury (2023)
- Autoregulatory Management in Traumatic Brain Injury (2023)
- Temperature Changes in Poor-Grade Aneurysmal Subarachnoid Hemorrhage (2023)
- Fine tuning of neurointensive care in aneurysmal subarachnoid hemorrhage (2023)
- Cerebral pressure autoregulation and optimal cerebral perfusion pressure during neurocritical care of children with traumatic brain injury (2023)
- Neurointensive care of traumatic brain injury in the elderly (2022)
- Prognosis in moderate-severe traumatic brain injury in a Swedish cohort and external validation of the IMPACT models (2022)
- Cerebral Pressure Autoregulation in Brain Injury and Disorders (2022)
- Low intracranial pressure variability is associated with delayed cerebral ischemia and unfavorable outcome in aneurysmal subarachnoid hemorrhage (2022)
- Post-traumatic hydrocephalus (2022)
- Cerebral Blood Flow and Oxygen Delivery in Aneurysmal Subarachnoid Hemorrhage (2022)
- Intracranial pressure dynamics and cerebral vasomotor reactivity in community-acquired bacterial meningitis during neurointensive care (2022)
- Females Exhibit Better Cerebral Pressure Autoregulation, Less Mitochondrial Dysfunction, and Reduced Excitotoxicity after Severe Traumatic Brain Injury (2022)
- Association of Arterial Metabolic Content with Cerebral Blood Flow Regulation and Cerebral Energy Metabolism-A Multimodality Analysis in Aneurysmal Subarachnoid Hemorrhage (2022)
- Intracranial pressure- and cerebral perfusion pressure threshold-insults in relation to cerebral energy metabolism in aneurysmal subarachnoid hemorrhage (2022)
- Incidence of Non-Syndromic and Syndromic Craniosynostosis in Sweden (2022)
- CBF changes and cerebral energy metabolism during hypervolemia, hemodilution, and hypertension therapy in patients with poor-grade subarachnoid hemorrhage (2021)
- Variable Temporal Cerebral Blood Flow Response to Acetazolamide in Moyamoya Patients Measured Using Arterial Spin Labeling (2021)
- Pre-injury chronic alcohol abuse predicts intracranial hemorrhagic progression, unfavorable clinical outcome, and mortality in severe traumatic brain injury (2021)
- Arterial Oxygenation in Traumatic Brain Injury (2021)
- Temporal Dynamics of ICP, CPP, PRx, and CPPopt in High-Grade Aneurysmal Subarachnoid Hemorrhage and the Relation to Clinical Outcome (2021)
- Systemic Hyperthermia in Traumatic Brain Injury—Relation to Intracranial Pressure Dynamics, Cerebral Energy Metabolism, and Clinical Outcome (2021)
- Autoregulatory or Fixed Cerebral Perfusion Pressure Targets in Traumatic Brain Injury (2021)
- Decompressive Craniectomy in Traumatic Brain Injury-Craniectomy-Related and Cranioplasty-Related Complications in a Single Center (2021)
- Pre-injury antithrombotic agents predict intracranial hemorrhagic progression, but not worse clinical outcome in severe traumatic brain injury (2021)
- In Reply to the Letter to the Editor Regarding "Decompressive Craniectomy in Traumatic Brain Injury-Craniectomy-Related and Cranioplasty-Related Complications in a Single Center" (2021)
- Fine Tuning of Traumatic Brain Injury Management in Neurointensive Care-Indicative Observations and Future Perspectives (2021)
- Temporal effects of barbiturate coma on intracranial pressure and compensatory reserve in children with traumatic brain injury (2021)
- High Intravascular Signal Arterial Transit Time Artifacts Have Negligible Effects on Cerebral Blood Flow and Cerebrovascular Reserve Capacity Measurement Using Single Postlabel Delay Arterial Spin-Labeling in Patients with Moyamoya Disease (2020)
- Arterial lactate in traumatic brain injury (2020)
- Intracranial pressure variability (2020)
- Mild hyperventilation in traumatic brain injury (2020)
- Intracranial Pressure Dynamics and Cerebral Vasomotor Reactivity in Coronavirus Disease 2019 Patient With Acute Encephalitis (2020)
- Intracranial pressure-based barbiturate coma treatment in children with refractory intracranial hypertension due to traumatic brain injury (2020)
- Intracranial pressure elevations in diffuse axonal injury (2019)
- Monitoring of Protein Biomarkers of Inflammation in Human Traumatic Brain Injury Using Microdialysis and Proximity Extension Assay Technology in Neurointensive Care (2019)
- Clinical outcome and prognostic factors in elderly traumatic brain injury patients receiving neurointensive care (2019)
- Temporal Neurophysiological Dynamics in Traumatic Brain Injury (2019)
- High Arterial Glucose is Associated with Poor Pressure Autoregulation, High Cerebral Lactate/Pyruvate Ratio and Poor Outcome Following Traumatic Brain Injury (2019)
- Dual lumen balloon catheter - An effective substitute for two single lumen catheters in treatment of vascular targets with challenging anatomy (2018)
- Hemodynamic Disturbances in the Early Phase After Subarachnoid Hemorrhage (2018)
- Effect of HHH-Therapy on Regional CBF after Severe Subarachnoid Hemorrhage Studied by Bedside Xenon-Enhanced CT (2018)
- A Dedicated 21-Plex Pea Panel For High-Sensitive Protein Biomarker Detection Using Micro-Dialysis In Traumatic Brain Injury (2018)
- Early low cerebral blood flow and high cerebral lactate (2018)
- Decompressive craniectomy in traumatic brain injury (2018)
- Increased risk of critical CBF levels in SAH patients with actual CPP below calculated optimal CPP (2017)
- The influence of hyperthermia on intracranial pressure, cerebral oximetry and cerebral metabolism in traumatic brain injury (2017)
- The Correlation between Cerebral Blood Flow Measured by Bedside Xenon-CT and Brain Chemistry Monitored by Microdialysis in the Acute Phase following Subarachnoid Hemorrhage (2017)
- Positive correlation between occlusion rate and nidus size of proton beam treated brain arteriovenous malformations (AVMs) (2016)
- Diffuse traumatic axonal injury in mice induces complex behavioural alterations that are normalized by neutralization of interleukin-1β (2016)
- Bedside Xenon-CT Shows Lower CBF in SAH Patients with Impaired CBF Pressure Autoregulation as Defined by Pressure Reactivity Index (PRx) (2016)
- Promising clinical outcome of elderly with TBI after modern neurointensive care (2016)
- Updated periodic evaluation of standardized neurointensive care shows that it is possible to maintain a high level of favorable outcome even with increasing mean age (2015)
- Refined microdialysis method for protein biomarker sampling in acute brain injury in the neurointensive care setting (2014)
- Acute neurosurgery for traumatic brain injury by general surgeons in Swedish county hospitals (2014)
- Cerebral microdialysis for protein biomarker monitoring in the neurointensive care setting - a technical approach (2014)
- New Microdialysis Method for Protein Biomarker Sampling in the Neurointensive Care Setting (2014)
- Should the Neurointensive Care Management of Traumatic Brain Injury Patients be Individualized According to Autoregulation Status and Injury Subtype? (2014)
- Brain tissue oxygenation and cerebral metabolic patterns in focal and diffuse traumatic brain injury (2014)
- Outcome from spontaneous subarachnoid haemorrhage (2014)
- Monitoring of Cerebral Blood Flow and Metabolism Bedside in Patients with Subarachnoid Hemorrhage - A Xenon-CT and Microdialysis Study (2014)
- The Neurological Wake-up Test Does not Alter Cerebral Energy Metabolism and Oxygenation in Patients with Severe Traumatic Brain Injury (2014)
- Traumatic axonal injury in the mouse is accompanied by a dynamic inflammatory response, astroglial reactivity and complex behavioral changes (2013)
- Introduction of the Uppsala Traumatic Brain Injury register for regular surveillance of patient characteristics and neurointensive care management including secondary insult quantification and clinical outcome (2013)
- Interstitial F2-Isoprostane 8-Iso-PGF2α As a Biomarker of Oxidative Stress after Severe Human Traumatic Brain Injury (2012)
- An evaluation of three measures of intracranial compliance in traumatic brain injury patients (2012)
- The use of nurse checklists in a bedside computer-based information system to focus on avoiding secondary insults in neurointensive care (2012)
- Brain Tissue Oxygenation and Cerebral Perfusion Pressure Thresholds of Ischemia in a Standardized Pig Brain Death Model (2012)
- Standardized experimental brain death model for studies of intracranial dynamics, organ preservation, and organ transplantation in the pig (2011)
- Vimentin and GFAP responses in astrocytes after contusion trauma to the murine brain (2010)
- The Multivariate Concentric Square Field Test Reveals Behavioral Profiles of Risk Taking, Exploration, and Cognitive Impairment in Mice Subjected to Traumatic Brain Injury (2010)
- Brain tissue oxygen monitoring (2010)
- Grafted neural progenitors migrate and form neurons after experimental traumatic brain injury (2009)
- The nitrone free radical scavenger NXY-059 is neuroprotective when administered after traumatic brain injury in the rat (2008)
- Distinct cellular patterns of upregulated chemokine expression supporting a prominent inflammatory role in traumatic brain injury (2008)
- T Lymphocyte trafficking (2007)
- Cerebral glutamine and glutamate levels in relation to compromised energy metabolism (2007)
- Genetically modified bone morphogenetic protein signalling alters traumatic brain injury-induced gene expression responses in the adult mouse (2006)
- Oxygen free radical-dependent activation of extracellular signal-regulated kinase mediates apoptosis-like cell death after traumatic brain injury (2004)
- Intracranial pressure elevations in diffuse axonal injury are associated with non-hemorrhagic MR lesions in central mesencephalic structures
- Machine learning based prediction of imminent ICP insults during neurocritical care of traumatic brain injury
- Cerebrovascular reactivity (PRx) and optimal cerebral perfusion pressure in elderly with traumatic brain injury.
- Decreased T-lymphocyte response to T-cell-dependent vaccines after neurotrauma or neurosurgery
Conferences
- Phantom-based evaluation of a planar microwave sensor for non-invasive intracranial pressure monitoring (2023)
- Initial In-Vitro Trial for Intra-Cranial Pressure Monitoring Using Subdermal Proximity-Coupled Split-Ring Resonator (2018)
- A Four-Layer Phantom for Testing In-Vitro Microwave-Based Sensing Approach in Intra-Cranial Pressure Monitoring (2018)
- Improved Microdialysis Sampling of Proteins using Surface Modified Catheters (2013)
