Anders Lewén

Promising clinical outcome of elderly with TBI after modern neurointensive care

Merzo, Abraham; Lenell, Samuel; Nyholm, Lena; Enblad, Per et al.

Ingår i Acta Neurochirurgica, s. 125-133, 2016

• DOI för Promising clinical outcome of elderly with TBI after modern neurointensive care

Positive correlation between occlusion rate and nidus size of proton beam treated brain arteriovenous malformations (AVMs)

Blomquist, Erik; Ronne Engström, Elisabeth; Borota, Ljubisa; Gál, Gyula et al.

Ingår i Acta Oncologica, s. 105-112, 2016

• DOI för Positive correlation between occlusion rate and nidus size of proton beam treated brain arteriovenous malformations (AVMs)

Updated periodic evaluation of standardized neurointensive care shows that it is possible to maintain a high level of favorable outcome even with increasing mean age

Lenell, Samuel; Nyholm, Lena; Lewen, Anders; Enblad, Per

Ingår i Acta Neurochirurgica, s. 417-425, 2015

• DOI för Updated periodic evaluation of standardized neurointensive care shows that it is possible to maintain a high level of favorable outcome even with increasing mean age

Outcome from spontaneous subarachnoid haemorrhage: results from 2007-2011 and comparison with our previous series

Ronne-Engström, Elisabeth; Borota, Ljubisa; Kothimbakam, Raj; Marklund, Niklas et al.

Ingår i Upsala Journal of Medical Sciences, s. 38-43, 2014

• DOI för Outcome from spontaneous subarachnoid haemorrhage: results from 2007-2011 and comparison with our previous series

Cerebral microdialysis for protein biomarker monitoring in the neurointensive care setting - a technical approach

Hillered, Lars; Dahlin, Andreas P; Clausen, Fredrik; Chu, Jiangtao et al.

Ingår i Frontiers in Neurology, s. 245, 2014

• DOI för Cerebral microdialysis for protein biomarker monitoring in the neurointensive care setting - a technical approach
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Monitoring of Cerebral Blood Flow and Metabolism Bedside in Patients with Subarachnoid Hemorrhage - A Xenon-CT and Microdialysis Study

Rostami, Elham; Engquist, Henrik; Johnson, Ulf; Howells, Timothy et al.

Ingår i Frontiers in Neurology, 2014

• DOI för Monitoring of Cerebral Blood Flow and Metabolism Bedside in Patients with Subarachnoid Hemorrhage - A Xenon-CT and Microdialysis Study
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Brain tissue oxygenation and cerebral metabolic patterns in focal and diffuse traumatic brain injury

Purins, Karlis; Lewén, Anders; Hillered, Lars; Howells, Timothy et al.

Ingår i Frontiers in Neurology, 2014

• DOI för Brain tissue oxygenation and cerebral metabolic patterns in focal and diffuse traumatic brain injury
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The Neurological Wake-up Test Does not Alter Cerebral Energy Metabolism and Oxygenation in Patients with Severe Traumatic Brain Injury

Skoglund, Karin; Hillered, Lars; Purins, Karlis; Tsitsopoulos, Parmenion P. et al.

Ingår i Neurocritical Care, s. 413-426, 2014

• DOI för The Neurological Wake-up Test Does not Alter Cerebral Energy Metabolism and Oxygenation in Patients with Severe Traumatic Brain Injury

Should the Neurointensive Care Management of Traumatic Brain Injury Patients be Individualized According to Autoregulation Status and Injury Subtype?

Johnson, Ulf; Lewen, Anders; Ronne-Engström, Elisabeth; Howells, Tim et al.

Ingår i Neurocritical Care, s. 259-265, 2014

• DOI för Should the Neurointensive Care Management of Traumatic Brain Injury Patients be Individualized According to Autoregulation Status and Injury Subtype?

New Microdialysis Method for Protein Biomarker Sampling in the Neurointensive Care Setting

Hillered, Lars; Dahlin, Andreas; Purins, Karlis; Wetterhall, Magnus et al.

Ingår i Journal of Neurotrauma, 2014

Acute neurosurgery for traumatic brain injury by general surgeons in Swedish county hospitals: A regional study

Fischerström, Ann; Nyholm, Lena; Lewen, Anders; Enblad, Per

Ingår i Acta Neurochirurgica, s. 177-185, 2014

• DOI för Acute neurosurgery for traumatic brain injury by general surgeons in Swedish county hospitals: A regional study

Refined microdialysis method for protein biomarker sampling in acute brain injury in the neurointensive care setting

Dahlin, Andreas P; Purins, Karlis; Clausen, Fredrik; Chu, Jiangtao et al.

Ingår i Analytical Chemistry, s. 8671-8679, 2014

• DOI för Refined microdialysis method for protein biomarker sampling in acute brain injury in the neurointensive care setting

Traumatic axonal injury in the mouse is accompanied by a dynamic inflammatory response, astroglial reactivity and complex behavioral changes

Ekmark-Lewén, Sara; Flygt, Johanna; Kiwanuka, Olivia; Meyerson, Bengt et al.

Ingår i Journal of Neuroinflammation, s. 44, 2013

• DOI för Traumatic axonal injury in the mouse is accompanied by a dynamic inflammatory response, astroglial reactivity and complex behavioral changes
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Introduction of the Uppsala Traumatic Brain Injury register for regular surveillance of patient characteristics and neurointensive care management including secondary insult quantification and clinical outcome

Nyholm, Lena; Howells, Tim; Enblad, Per; Lewen, Anders

Ingår i Upsala Journal of Medical Sciences, s. 169-180, 2013

• DOI för Introduction of the Uppsala Traumatic Brain Injury register for regular surveillance of patient characteristics and neurointensive care management including secondary insult quantification and clinical outcome

Improved Microdialysis Sampling of Proteins using Surface Modified Catheters: An in vivo Study in Standardized Pig Brain Death Model

Dahlin, Andreas P; Purins, Karlis; Lewen, Anders; Hillered, Lars

2013

The use of nurse checklists in a bedside computer-based information system to focus on avoiding secondary insults in neurointensive care

Nyholm, Lena; Lewén, Anders; Fröjd, Camilla; Howells, Tim et al.

Ingår i ISRN Neurology, s. 903954, 2012

• DOI för The use of nurse checklists in a bedside computer-based information system to focus on avoiding secondary insults in neurointensive care

An evaluation of three measures of intracranial compliance in traumatic brain injury patients

Howells, Tim; Lewen, Anders; Sköld, Mattias K.; Ronne-Engström, Elisabeth et al.

Ingår i Intensive Care Medicine, s. 1061-1068, 2012

• DOI för An evaluation of three measures of intracranial compliance in traumatic brain injury patients

Brain Tissue Oxygenation and Cerebral Perfusion Pressure Thresholds of Ischemia in a Standardized Pig Brain Death Model

Purins, Karlis; Enblad, Per; Wiklund, Lars; Lewén, Anders

Ingår i Neurocritical Care, s. 462-469, 2012

• DOI för Brain Tissue Oxygenation and Cerebral Perfusion Pressure Thresholds of Ischemia in a Standardized Pig Brain Death Model

Interstitial F₂-Isoprostane 8-Iso-PGF_2α As a Biomarker of Oxidative Stress after Severe Human Traumatic Brain Injury

Clausen, Fredrik; Marklund, Niklas; Lewén, Anders; Enblad, Per et al.

Ingår i Journal of Neurotrauma, s. 766-775, 2012

• DOI för Interstitial F₂-Isoprostane 8-Iso-PGF_2α As a Biomarker of Oxidative Stress after Severe Human Traumatic Brain Injury

The nitrone free radical scavenger NXY-059 is neuroprotective when administered after traumatic brain injury in the rat

Clausen, Fredrik; Marklund, Niklas; Lewén, Anders; Hillered, Lars

Ingår i Journal of Neurotrauma, s. 1449-1457, 2008

• DOI för The nitrone free radical scavenger NXY-059 is neuroprotective when administered after traumatic brain injury in the rat

Oxygen free radical-dependent activation of extracellular signal-regulated kinase mediates apoptosis-like cell death after traumatic brain injury

Clausen, Fredrik; Lundqvist, Hanna; Ekmark, Sara; Lewen, Anders et al.

Ingår i Journal of Neurotrauma, s. 1168-1182, 2004

• DOI för Oxygen free radical-dependent activation of extracellular signal-regulated kinase mediates apoptosis-like cell death after traumatic brain injury

Proteomic blood-based biomarkers of brain damage in traumatic brain injury: are they suitable surrogate endpoints for cerebral pressure autoregulatory-guided therapy?

Kevci, Rozerin; Hånell, Anders; Aries, Marcel; Akerlund, Cecilia et al.

Ingår i Critical Care, 2026

• DOI för Proteomic blood-based biomarkers of brain damage in traumatic brain injury: are they suitable surrogate endpoints for cerebral pressure autoregulatory-guided therapy?
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Temporal dynamics of ICP, PRx, CPP, and CPPopt in relation to functional outcome in spontaneous cerebellar hemorrhage

Kevci, Rozerin; Hånell, Anders; Sida, Hilin; Alhamdan, Modar et al.

Ingår i Critical Care, 2026

• DOI för Temporal dynamics of ICP, PRx, CPP, and CPPopt in relation to functional outcome in spontaneous cerebellar hemorrhage
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The Effects of Hyper- and Hypoventilation on Cerebral Physiology in a Healthy and Compromised Brain State: An Experimental Pig Model with State-of-the-Art Neuromonitoring

Svedung-Wettervik, Teodor; Joensen, Odin; Alhamdan, Modar; Hånell, Anders et al.

Ingår i Journal of Neurotrauma, s. 161-174, 2026

• DOI för The Effects of Hyper- and Hypoventilation on Cerebral Physiology in a Healthy and Compromised Brain State: An Experimental Pig Model with State-of-the-Art Neuromonitoring

Lead times in the early management of traumatic brain injury: relation to geographic conditions and clinical outcomes in a nationwide Swedish registry study

Gu, Amanda; Leal-Mendez, Francisco; Lewén, Anders; Hånell, Anders et al.

Ingår i Acta Neurochirurgica, 2026

• DOI för Lead times in the early management of traumatic brain injury: relation to geographic conditions and clinical outcomes in a nationwide Swedish registry study
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Visualizations of Autoregulatory Insults in Traumatic Brain Injury: A Collaborative European NeuroTrauma Effectiveness Research-Traumatic Brain Injury Cohort Study

Kevci, Rozerin; Hånell, Anders; Lewén, Anders; Enblad, Per et al.

Ingår i Journal of Neurotrauma, s. 429-441, 2026

• DOI för Visualizations of Autoregulatory Insults in Traumatic Brain Injury: A Collaborative European NeuroTrauma Effectiveness Research-Traumatic Brain Injury Cohort Study

Proteomic blood-based biomarkers of brain damage in traumatic brain injury: are they suitable surrogate endpoints for cerebral pressure autoregulatory-guided therapy?

Kevci, Rozerin; Hånell, Anders; Aries, Marcel; Akerlund, Cecilia et al.

Ingår i Critical Care, 2026

• DOI för Proteomic blood-based biomarkers of brain damage in traumatic brain injury: are they suitable surrogate endpoints for cerebral pressure autoregulatory-guided therapy?
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Temporal dynamics of ICP, PRx, CPP, and CPPopt in relation to functional outcome in spontaneous cerebellar hemorrhage

Kevci, Rozerin; Hånell, Anders; Sida, Hilin; Alhamdan, Modar et al.

Ingår i Critical Care, 2026

• DOI för Temporal dynamics of ICP, PRx, CPP, and CPPopt in relation to functional outcome in spontaneous cerebellar hemorrhage
• Ladda ner fulltext (pdf) av Temporal dynamics of ICP, PRx, CPP, and CPPopt in relation to functional outcome in spontaneous cerebellar hemorrhage

The Effects of Hyper- and Hypoventilation on Cerebral Physiology in a Healthy and Compromised Brain State: An Experimental Pig Model with State-of-the-Art Neuromonitoring

Svedung-Wettervik, Teodor; Joensen, Odin; Alhamdan, Modar; Hånell, Anders et al.

Ingår i Journal of Neurotrauma, s. 161-174, 2026

• DOI för The Effects of Hyper- and Hypoventilation on Cerebral Physiology in a Healthy and Compromised Brain State: An Experimental Pig Model with State-of-the-Art Neuromonitoring

Lead times in the early management of traumatic brain injury: relation to geographic conditions and clinical outcomes in a nationwide Swedish registry study

Gu, Amanda; Leal-Mendez, Francisco; Lewén, Anders; Hånell, Anders et al.

Ingår i Acta Neurochirurgica, 2026

• DOI för Lead times in the early management of traumatic brain injury: relation to geographic conditions and clinical outcomes in a nationwide Swedish registry study
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Visualizations of Autoregulatory Insults in Traumatic Brain Injury: A Collaborative European NeuroTrauma Effectiveness Research-Traumatic Brain Injury Cohort Study

Kevci, Rozerin; Hånell, Anders; Lewén, Anders; Enblad, Per et al.

Ingår i Journal of Neurotrauma, s. 429-441, 2026

• DOI för Visualizations of Autoregulatory Insults in Traumatic Brain Injury: A Collaborative European NeuroTrauma Effectiveness Research-Traumatic Brain Injury Cohort Study

Perioperative outcomes of craniosynostosis: Experience of a newly established national reference center for pediatric craniofacial surgery

Nowinski, Daniel; Stefansdottir, Andrea Bara; Magneli, Sara; Lewén, Anders et al.

Ingår i Journal of Plastic, Reconstructive & Aesthetic Surgery, s. 1-8, 2026

• DOI för Perioperative outcomes of craniosynostosis: Experience of a newly established national reference center for pediatric craniofacial surgery

Overall outcome, functioning, and disability in older adults 3 to 14 years after traumatic brain injury

von Seth, Charlotta; Lewén, Anders; Lannsjö, Marianne; Enblad, Per et al.

Ingår i PM&R, s. 398-409, 2026

• DOI för Overall outcome, functioning, and disability in older adults 3 to 14 years after traumatic brain injury
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Treatment strategies, complications, and outcomes in spontaneous cerebellar hemorrhage: a swedish observational single-center study

Sida, Hilin; Kevci, Rozerin; Velle, Fartein; Lewén, Anders et al.

Ingår i Acta Neurochirurgica, 2026

• DOI för Treatment strategies, complications, and outcomes in spontaneous cerebellar hemorrhage: a swedish observational single-center study
• Ladda ner fulltext (pdf) av Treatment strategies, complications, and outcomes in spontaneous cerebellar hemorrhage: a swedish observational single-center study

Decompressive craniectomy in traumatic brain injury: insights from a 15-year multicentre cohort in Sweden

Leal-Méndez, Francisco; Holmgren, Klas; Corell, Alba; Nesic, Tijana et al.

Ingår i Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2026

• DOI för Decompressive craniectomy in traumatic brain injury: insights from a 15-year multicentre cohort in Sweden
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The effects of hyperglycemia on brain physiology in a healthy and injured state: An experimental pig study with state-of-the-art multimodal neuromonitoring

Svedung-Wettervik, Teodor; Hånell, Anders; Ahlgren, Kerstin; Engquist, Henrik et al.

Ingår i Journal of Cerebral Blood Flow and Metabolism, s. 2245-2255, 2025

• DOI för The effects of hyperglycemia on brain physiology in a healthy and injured state: An experimental pig study with state-of-the-art multimodal neuromonitoring
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Individualized, Autoregulatory-guided Intracranial Pressure and Cerebral Perfusion Pressure Targets in Severe Cerebral Venous Thrombosis: Preliminary Findings

Hejdenberg, Olle; Hånell, Anders; Lewén, Anders; Enblad, Per et al.

Ingår i Journal of Neurosurgical Anesthesiology, s. 379-386, 2025

• DOI för Individualized, Autoregulatory-guided Intracranial Pressure and Cerebral Perfusion Pressure Targets in Severe Cerebral Venous Thrombosis: Preliminary Findings

Regional variation in traumatic brain injury patterns, management and mortality: a nationwide Swedish cohort study

Leal-Méndez, Francisco; Lewén, Anders; Gu, Amanda; Hånell, Anders et al.

Ingår i Acta Neurochirurgica, 2025

• DOI för Regional variation in traumatic brain injury patterns, management and mortality: a nationwide Swedish cohort study
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Temporal dynamics of ICP, CPP, PRx, and CPPopt in relation to outcome in spontaneous intracerebral hemorrhage

Kevci, Rozerin; Hånell, Anders; Howells, Timothy; Fahlström, Andreas et al.

Ingår i Journal of Neurosurgery, s. 255-265, 2025

• DOI för Temporal dynamics of ICP, CPP, PRx, and CPPopt in relation to outcome in spontaneous intracerebral hemorrhage

Intracranial pressure dynamics, cerebral autoregulation, and brain perfusion after decompressive craniectomy in malignant middle cerebral artery infarction: is there a role for invasive monitoring?

Alhamdan, Modar; Hånell, Anders; Howells, Timothy; Lewén, Anders et al.

Ingår i Acta Neurochirurgica, 2025

• DOI för Intracranial pressure dynamics, cerebral autoregulation, and brain perfusion after decompressive craniectomy in malignant middle cerebral artery infarction: is there a role for invasive monitoring?
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Intracranial response to positive end-expiratory pressure is influenced by lung recruitability and gas distribution during mechanical ventilation in acute brain injury patients: a proof-of-concept physiological study

Bencze, Reka; Kawati, Rafael; Hånell, Anders; Lewen, Anders et al.

Ingår i Intensive Care Medicine Experimental, 2025

• DOI för Intracranial response to positive end-expiratory pressure is influenced by lung recruitability and gas distribution during mechanical ventilation in acute brain injury patients: a proof-of-concept physiological study
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Chronic, Shunt-Dependent Hydrocephalus in Aneurysmal Subarachnoid Hemorrhage: Incidence, Risk Factors, Clinical Phenotypes, and Outcome

Larsson, Lydia; Vedung, Fredrik; Virhammar, Johan; Ronne-Engström, Elisabeth et al.

Ingår i World Neurosurgery, 2025

• DOI för Chronic, Shunt-Dependent Hydrocephalus in Aneurysmal Subarachnoid Hemorrhage: Incidence, Risk Factors, Clinical Phenotypes, and Outcome
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Influence of apolipoprotein E genotype on the proteomic profile in cerebral microdialysis after human severe traumatic brain injury: a prospective observational study

Lindblad, Caroline; Klang, Andrea; Bark, David; Bellotti, Cristina et al.

Ingår i Brain Communications, 2025

• DOI för Influence of apolipoprotein E genotype on the proteomic profile in cerebral microdialysis after human severe traumatic brain injury: a prospective observational study
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Preliminary Observations of the Loke Microdialysis in an Experimental Pig Model: Are We Ready for Continuous Monitoring of Brain Energy Metabolism?

Svedung-Wettervik, Teodor; Hånell, Anders; Ahlgren, Kerstin; Hillered, Lars et al.

Ingår i Neurocritical Care, s. 222-231, 2025

• DOI för Preliminary Observations of the Loke Microdialysis in an Experimental Pig Model: Are We Ready for Continuous Monitoring of Brain Energy Metabolism?
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Refining outcome prediction after traumatic brain injury with machine learning algorithms

Bark, D.; Boman, M.; Depreitere, B.; Wright, D. W. et al.

Ingår i Scientific Reports, 2024

• DOI för Refining outcome prediction after traumatic brain injury with machine learning algorithms
• Ladda ner fulltext (pdf) av Refining outcome prediction after traumatic brain injury with machine learning algorithms

Machine Learning Based Prediction of Imminent ICP Insults During Neurocritical Care of Traumatic Brain Injury

Galos, Peter; Hult, Ludvig; Zachariah, Dave; Lewén, Anders et al.

Ingår i Neurocritical Care, s. 387-397, 2024

• DOI för Machine Learning Based Prediction of Imminent ICP Insults During Neurocritical Care of Traumatic Brain Injury
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Volumetric Assessment of Traumatic Intracranial Hematomas: Is ABC/2 Reliable?

Fletcher-Sandersjöö, Alexander; Lewén, Anders; Hånell, Anders; Nelson, David W. et al.

Ingår i Journal of Neurotrauma, s. 2545-2553, 2024

• DOI för Volumetric Assessment of Traumatic Intracranial Hematomas: Is ABC/2 Reliable?

The Optimal pressure reactivity index range is disease-specific: A comparison between aneurysmal subarachnoid hemorrhage and traumatic brain injury

Svedung-Wettervik, Teodor; Howells, Timothy; Hånell, Anders; Lewén, Anders et al.

Ingår i Journal of clinical monitoring and computing, s. 1089-1099, 2024

• DOI för The Optimal pressure reactivity index range is disease-specific: A comparison between aneurysmal subarachnoid hemorrhage and traumatic brain injury
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Individualized Autoregulation-Derived Cerebral Perfusion Targets in Aneurysmal Subarachnoid Hemorrhage: A New Therapeutic Avenue?

Svedung-Wettervik, Teodor; Hånell, Anders; Howells, Timothy; Ronne-Engström, Elisabeth et al.

Ingår i Journal of Intensive Care Medicine, s. 1083-1092, 2024

• DOI för Individualized Autoregulation-Derived Cerebral Perfusion Targets in Aneurysmal Subarachnoid Hemorrhage: A New Therapeutic Avenue?
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Emergency neurosurgery for traumatic brain injury by general surgeons at local hospitals in Sweden: a viable option when time is brain

Leal-Méndez, Francisco; Holmberg, Lina; Enblad, Per; Lewén, Anders et al.

Ingår i Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2024

• DOI för Emergency neurosurgery for traumatic brain injury by general surgeons at local hospitals in Sweden: a viable option when time is brain
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Trends in incidence and treatments of spontaneous subarachnoid hemorrhage: a 10 year hospital based study

Ronne-Engström, Elisabeth; Borota, Ljubisa; Lenell, Samuel; Lewén, Anders et al.

Ingår i Acta Neurochirurgica, 2024

• DOI för Trends in incidence and treatments of spontaneous subarachnoid hemorrhage: a 10 year hospital based study
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A mathematical model for temporal cerebral blood flow response to acetazolamide evaluated in patients with Moyamoya disease

Fahlström, Markus; Sousa, Joao M.; Svedung Wettervik, Teodor; Berglund, Johan et al.

Ingår i Magnetic Resonance Imaging, s. 35-42, 2024

• DOI för A mathematical model for temporal cerebral blood flow response to acetazolamide evaluated in patients with Moyamoya disease
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Autoregulatory Cerebral Perfusion Pressure Insults in Traumatic Brain Injury and Aneurysmal Subarachnoid Hemorrhage: The Role of Insult Intensity and Duration on Clinical Outcome

Svedung Wettervik, Teodor; Hånell, Anders; Howells, Timothy; Engström, Elisabeth R. et al.

Ingår i Journal of Neurosurgical Anesthesiology, s. 228-236, 2024

• DOI för Autoregulatory Cerebral Perfusion Pressure Insults in Traumatic Brain Injury and Aneurysmal Subarachnoid Hemorrhage: The Role of Insult Intensity and Duration on Clinical Outcome

Absolute Contusion Expansion Is Superior to Relative Expansion in Predicting Traumatic Brain Injury Outcomes: A Multi-Center Observational Cohort Study

Fletcher-Sandersjöö, Alexander; Svedung Wettervik, Teodor; Tatter, Charles; Tjerkaski, Jonathan et al.

Ingår i Journal of Neurotrauma, s. 705-713, 2024

• DOI för Absolute Contusion Expansion Is Superior to Relative Expansion in Predicting Traumatic Brain Injury Outcomes: A Multi-Center Observational Cohort Study
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The effects of cerebral pressure autoregulation status and CPP levels on cerebral metabolism in pediatric traumatic brain injury

Velle, Fartein; Lewén, Anders; Howells, Tim; Hånell, Anders et al.

Ingår i Acta Neurochirurgica, 2024

• DOI för The effects of cerebral pressure autoregulation status and CPP levels on cerebral metabolism in pediatric traumatic brain injury
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Cerebrovascular reactivity (PRx) and optimal cerebral perfusion pressure in elderly with traumatic brain injury

Lenell, Samuel; Svedung-Wettervik, Teodor; Howells, Timothy; Hånell, Anders et al.

Ingår i Acta Neurochirurgica, 2024

• DOI för Cerebrovascular reactivity (PRx) and optimal cerebral perfusion pressure in elderly with traumatic brain injury
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Cerebral pressure autoregulation and optimal cerebral perfusion pressure during neurocritical care of children with traumatic brain injury

Velle, Fartein; Lewén, Anders; Howells, Timothy; Hånell, Anders et al.

Ingår i Journal of Neurosurgery, s. 503-513, 2023

• DOI för Cerebral pressure autoregulation and optimal cerebral perfusion pressure during neurocritical care of children with traumatic brain injury

Thiopental and decompressive craniectomy as last-tier ICP-treatments in aneurysmal subarachnoid hemorrhage: is functional recovery within reach?

Björk, Sofie; Hånell, Anders; Ronne-Engström, Elisabeth; Stenwall, Per-Anton et al.

Ingår i Neurosurgical review, 2023

• DOI för Thiopental and decompressive craniectomy as last-tier ICP-treatments in aneurysmal subarachnoid hemorrhage: is functional recovery within reach?
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Fine tuning of neurointensive care in aneurysmal subarachnoid hemorrhage: From one-size-fits-all towards individualized care

Svedung-Wettervik, Teodor; Lewén, Anders; Enblad, Per

Ingår i World Neurosurgery: X, s. 100160, 2023

• DOI för Fine tuning of neurointensive care in aneurysmal subarachnoid hemorrhage: From one-size-fits-all towards individualized care
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Cerebral Microdialysis Monitoring of Energy Metabolism: Relation to Cerebral Blood Flow and Oxygen Delivery in Aneurysmal Subarachnoid Hemorrhage

Svedung-Wettervik, Teodor; Engquist, Henrik; Hånell, Anders; Howells, Timothy et al.

Ingår i Journal of Neurosurgical Anesthesiology, s. 384-393, 2023

• DOI för Cerebral Microdialysis Monitoring of Energy Metabolism: Relation to Cerebral Blood Flow and Oxygen Delivery in Aneurysmal Subarachnoid Hemorrhage

A Dedicated 21-Plex Proximity Extension Assay Panel for High-Sensitivity Protein Biomarker Detection Using Microdialysis in Severe Traumatic Brain Injury: The Next Step in Precision Medicine?

Dyhrfort, Philip; Svedung-Wettervik, Teodor; Clausen, Fredrik; Enblad, Per et al.

Ingår i NEUROTRAUMA REPORTS, s. 25-40, 2023

• DOI för A Dedicated 21-Plex Proximity Extension Assay Panel for High-Sensitivity Protein Biomarker Detection Using Microdialysis in Severe Traumatic Brain Injury: The Next Step in Precision Medicine?
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Autoregulatory Management in Traumatic Brain Injury: The Role of Absolute Pressure Reactivity Index Values and Optimal Cerebral Perfusion Pressure Curve Shape

Svedung-Wettervik, Teodor; Hånell, Anders; Howells, Timothy; Lewén, Anders et al.

Ingår i Journal of Neurotrauma, s. 2341-2352, 2023

• DOI för Autoregulatory Management in Traumatic Brain Injury: The Role of Absolute Pressure Reactivity Index Values and Optimal Cerebral Perfusion Pressure Curve Shape

Antithrombotic agent usage before ictus in aneurysmal subarachnoid hemorrhage: relation to hemorrhage severity, clinical course, and outcome

Kultanen, Hanna; Lewén, Anders; Ronne-Engström, Elisabeth; Enblad, Per et al.

Ingår i Acta Neurochirurgica, s. 1241-1250, 2023

• DOI för Antithrombotic agent usage before ictus in aneurysmal subarachnoid hemorrhage: relation to hemorrhage severity, clinical course, and outcome
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ASL-MRI-guided evaluation of multiple burr hole revascularization surgery in Moyamoya disease

Lewén, Anders; Fahlström, Markus; Borota, Ljubisa; Larsson, Elna-Marie et al.

Ingår i Acta Neurochirurgica, s. 2057-2069, 2023

• DOI för ASL-MRI-guided evaluation of multiple burr hole revascularization surgery in Moyamoya disease
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Intracranial lesion features in moderate-to-severe traumatic brain injury: relation to neurointensive care variables and clinical outcome

Svedung-Wettervik, Teodor; Hånell, Anders; Enblad, Per; Lewén, Anders

Ingår i Acta Neurochirurgica, s. 2389-2398, 2023

• DOI för Intracranial lesion features in moderate-to-severe traumatic brain injury: relation to neurointensive care variables and clinical outcome
• Ladda ner fulltext (pdf) av Intracranial lesion features in moderate-to-severe traumatic brain injury: relation to neurointensive care variables and clinical outcome

Temperature Changes in Poor-Grade Aneurysmal Subarachnoid Hemorrhage: Relation to Injury Pattern, Intracranial Pressure Dynamics, Cerebral Energy Metabolism, and Clinical Outcome

Svedung-Wettervik, Teodor; Hånell, Anders; Ronne-Engström, Elisabeth; Lewén, Anders et al.

Ingår i Neurocritical Care, s. 145-154, 2023

• DOI för Temperature Changes in Poor-Grade Aneurysmal Subarachnoid Hemorrhage: Relation to Injury Pattern, Intracranial Pressure Dynamics, Cerebral Energy Metabolism, and Clinical Outcome
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Editorial: Moyamoya disease - natural history and therapeutic challenges

Svedung-Wettervik, Teodor; Fahlström, Markus; Wikström, Johan; Enblad, Per et al.

Ingår i Frontiers in Neurology, 2023

• DOI för Editorial: Moyamoya disease - natural history and therapeutic challenges
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ICP, PRx, CPP, and ∆CPPopt in pediatric traumatic brain injury: the combined effect of insult intensity and duration on outcome

Svedung Wettervik, Teodor; Velle, Fartein; Hånell, Anders; Howells, Timothy et al.

Ingår i Child's Nervous System, s. 2459-2466, 2023

• DOI för ICP, PRx, CPP, and ∆CPPopt in pediatric traumatic brain injury: the combined effect of insult intensity and duration on outcome
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Lumbar puncture-verified subarachnoid hemorrhage: bleeding sources, need of radiological examination, and functional recovery

Kevci, Rozerin; Lewén, Anders; Ronne-Engström, Elisabeth; Velle, Fartein et al.

Ingår i Acta Neurochirurgica, s. 1847-1854, 2023

• DOI för Lumbar puncture-verified subarachnoid hemorrhage: bleeding sources, need of radiological examination, and functional recovery
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Evaluation of single-delay arterial spin labeling-based spatial coefficient of variation and histogram-based parameters in relation to cerebrovascular reserve in patients with Moyamoya disease.

Fahlström, Markus; Svedung-Wettervik, Teodor; Enblad, Per; Lewén, Anders et al.

Ingår i Frontiers in Neurology, 2023

• DOI för Evaluation of single-delay arterial spin labeling-based spatial coefficient of variation and histogram-based parameters in relation to cerebrovascular reserve in patients with Moyamoya disease.
• Ladda ner fulltext (pdf) av Evaluation of single-delay arterial spin labeling-based spatial coefficient of variation and histogram-based parameters in relation to cerebrovascular reserve in patients with Moyamoya disease.

Intracranial Pressure Variability: A New Potential Metric of Cerebral Ischemia and Energy Metabolic Dysfunction in Aneurysmal Subarachnoid Hemorrhage?

Svedung Wettervik, Teodor; Howells, Timothy; Hånell, Anders; Ronne-Engström, Elisabeth et al.

Ingår i Journal of Neurosurgical Anesthesiology, s. 208-214, 2023

• DOI för Intracranial Pressure Variability: A New Potential Metric of Cerebral Ischemia and Energy Metabolic Dysfunction in Aneurysmal Subarachnoid Hemorrhage?

ICP, CPP, and PRx in traumatic brain injury and aneurysmal subarachnoid hemorrhage: association of insult intensity and duration with clinical outcome

Svedung Wettervik, Teodor; Hånell, Anders; Howells, Timothy; Ronne Engström, Elisabeth et al.

Ingår i Journal of Neurosurgery, s. 446-453, 2023

• DOI för ICP, CPP, and PRx in traumatic brain injury and aneurysmal subarachnoid hemorrhage: association of insult intensity and duration with clinical outcome

Higher Intracranial Pressure Variability is Associated with Lower Cerebrovascular Resistance in Aneurysmal Subarachnoid Hemorrhage

Svedung-Wettervik, Teodor; Engquist, Henrik; Howells, Timothy; Hånell, Anders et al.

Ingår i Journal of clinical monitoring and computing, s. 319-326, 2023

• DOI för Higher Intracranial Pressure Variability is Associated with Lower Cerebrovascular Resistance in Aneurysmal Subarachnoid Hemorrhage
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Intracranial pressure dynamics and cerebral vasomotor reactivity in community-acquired bacterial meningitis during neurointensive care

Svedung-Wettervik, Teodor; Howells, Timothy; Ljunghill Hedberg, Anna; Lewén, Anders et al.

Ingår i Journal of Neurosurgery, s. 831-839, 2022

• DOI för Intracranial pressure dynamics and cerebral vasomotor reactivity in community-acquired bacterial meningitis during neurointensive care

Prognosis in moderate-severe traumatic brain injury in a Swedish cohort and external validation of the IMPACT models

Rostami, Elham; Gustafsson, David; Hånell, Anders; Howells, Timothy et al.

Ingår i Acta Neurochirurgica, s. 615-624, 2022

• DOI för Prognosis in moderate-severe traumatic brain injury in a Swedish cohort and external validation of the IMPACT models
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Association of Arterial Metabolic Content with Cerebral Blood Flow Regulation and Cerebral Energy Metabolism-A Multimodality Analysis in Aneurysmal Subarachnoid Hemorrhage

Svedung-Wettervik, Teodor; Hånell, Anders; Howells, Timothy; Ronne-Engström, Elisabeth et al.

Ingår i Journal of Intensive Care Medicine, s. 1442-1450, 2022

• DOI för Association of Arterial Metabolic Content with Cerebral Blood Flow Regulation and Cerebral Energy Metabolism-A Multimodality Analysis in Aneurysmal Subarachnoid Hemorrhage
• Ladda ner fulltext (pdf) av Association of Arterial Metabolic Content with Cerebral Blood Flow Regulation and Cerebral Energy Metabolism-A Multimodality Analysis in Aneurysmal Subarachnoid Hemorrhage

Neurointensive care of traumatic brain injury in the elderly: age-specific secondary insult levels and optimal physiological levels to target need to be defined

Lenell, Samuel; Lewén, Anders; Howells, Timothy; Enblad, Per

Ingår i Acta Neurochirurgica, s. 117-128, 2022

• DOI för Neurointensive care of traumatic brain injury in the elderly: age-specific secondary insult levels and optimal physiological levels to target need to be defined
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Cerebral Blood Flow and Oxygen Delivery in Aneurysmal Subarachnoid Hemorrhage: Relation to Neurointensive Care Targets

Svedung-Wettervik, Teodor; Engquist, Henrik; Hånell, Anders; Howells, Timothy et al.

Ingår i Neurocritical Care, s. 281-292, 2022

• DOI för Cerebral Blood Flow and Oxygen Delivery in Aneurysmal Subarachnoid Hemorrhage: Relation to Neurointensive Care Targets
• Ladda ner fulltext (pdf) av Cerebral Blood Flow and Oxygen Delivery in Aneurysmal Subarachnoid Hemorrhage: Relation to Neurointensive Care Targets

Incidence of Non-Syndromic and Syndromic Craniosynostosis in Sweden

Tarnow, Peter; Kölby, Lars; Maltese, Giovanni; Söfteland, Madiha Bhatti et al.

Ingår i The Journal of Craniofacial Surgery, s. 1517-1520, 2022

• DOI för Incidence of Non-Syndromic and Syndromic Craniosynostosis in Sweden

Low intracranial pressure variability is associated with delayed cerebral ischemia and unfavorable outcome in aneurysmal subarachnoid hemorrhage

Svedung Wettervik, Teodor; Howells, Timothy; Hånell, Anders; Ronne-Engström, Elisabeth et al.

Ingår i Journal of clinical monitoring and computing, s. 569-578, 2022

• DOI för Low intracranial pressure variability is associated with delayed cerebral ischemia and unfavorable outcome in aneurysmal subarachnoid hemorrhage
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Post-traumatic hydrocephalus: incidence, risk factors, treatment, and clinical outcome

Svedung Wettervik, Teodor; Lewén, Anders; Enblad, Per

Ingår i British Journal of Neurosurgery, s. 400-406, 2022

• DOI för Post-traumatic hydrocephalus: incidence, risk factors, treatment, and clinical outcome
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Females Exhibit Better Cerebral Pressure Autoregulation, Less Mitochondrial Dysfunction, and Reduced Excitotoxicity after Severe Traumatic Brain Injury

Svedung-Wettervik, Teodor; Hånell, Anders; Howells, Timothy; Enblad, Per et al.

Ingår i Journal of Neurotrauma, s. 1507-1517, 2022

• DOI för Females Exhibit Better Cerebral Pressure Autoregulation, Less Mitochondrial Dysfunction, and Reduced Excitotoxicity after Severe Traumatic Brain Injury

Intracranial pressure- and cerebral perfusion pressure threshold-insults in relation to cerebral energy metabolism in aneurysmal subarachnoid hemorrhage

Svedung-Wettervik, Teodor; Hånell, Anders; Howells, Timothy; Ronne-Engström, Elisabeth et al.

Ingår i Acta Neurochirurgica, s. 1001-1014, 2022

• DOI för Intracranial pressure- and cerebral perfusion pressure threshold-insults in relation to cerebral energy metabolism in aneurysmal subarachnoid hemorrhage
• Ladda ner fulltext (pdf) av Intracranial pressure- and cerebral perfusion pressure threshold-insults in relation to cerebral energy metabolism in aneurysmal subarachnoid hemorrhage

Systemic Hyperthermia in Traumatic Brain Injury—Relation to Intracranial Pressure Dynamics, Cerebral Energy Metabolism, and Clinical Outcome

Svedung-Wettervik, Teodor; Engquist, Henrik; Lenell, Samuel; Howells, Timothy et al.

Ingår i Journal of Neurosurgical Anesthesiology, s. 329-336, 2021

• DOI för Systemic Hyperthermia in Traumatic Brain Injury—Relation to Intracranial Pressure Dynamics, Cerebral Energy Metabolism, and Clinical Outcome

In Reply to the Letter to the Editor Regarding "Decompressive Craniectomy in Traumatic Brain Injury-Craniectomy-Related and Cranioplasty-Related Complications in a Single Center"

Svedung-Wettervik, Teodor; Lewén, Anders

Ingår i World Neurosurgery, s. 203-203, 2021

• DOI för In Reply to the Letter to the Editor Regarding "Decompressive Craniectomy in Traumatic Brain Injury-Craniectomy-Related and Cranioplasty-Related Complications in a Single Center"

Temporal effects of barbiturate coma on intracranial pressure and compensatory reserve in children with traumatic brain injury

Velle, Fartein; Lewén, Anders; Howells, Timothy; Nilsson, Pelle et al.

Ingår i Acta Neurochirurgica, s. 489-498, 2021

• DOI för Temporal effects of barbiturate coma on intracranial pressure and compensatory reserve in children with traumatic brain injury
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Autoregulatory or Fixed Cerebral Perfusion Pressure Targets in Traumatic Brain Injury: Determining Which Is Better in an Energy Metabolic Perspective

Svedung-Wettervik, Teodor; Howells, Timothy; Hillered, Lars; Rostami, Elham et al.

Ingår i Journal of Neurotrauma, s. 1969-1978, 2021

• DOI för Autoregulatory or Fixed Cerebral Perfusion Pressure Targets in Traumatic Brain Injury: Determining Which Is Better in an Energy Metabolic Perspective

Pre-injury antithrombotic agents predict intracranial hemorrhagic progression, but not worse clinical outcome in severe traumatic brain injury

Svedung-Wettervik, Teodor; Lenell, Samuel; Enblad, Per; Lewén, Anders

Ingår i Acta Neurochirurgica, s. 1403-1413, 2021

• DOI för Pre-injury antithrombotic agents predict intracranial hemorrhagic progression, but not worse clinical outcome in severe traumatic brain injury
• Ladda ner fulltext (pdf) av Pre-injury antithrombotic agents predict intracranial hemorrhagic progression, but not worse clinical outcome in severe traumatic brain injury

Pre-injury chronic alcohol abuse predicts intracranial hemorrhagic progression, unfavorable clinical outcome, and mortality in severe traumatic brain injury

Svedung Wettervik, Teodor; Enblad, Per; Lewén, Anders

Ingår i Brain Injury, s. 1569-1576, 2021

• DOI för Pre-injury chronic alcohol abuse predicts intracranial hemorrhagic progression, unfavorable clinical outcome, and mortality in severe traumatic brain injury
• Ladda ner fulltext (pdf) av Pre-injury chronic alcohol abuse predicts intracranial hemorrhagic progression, unfavorable clinical outcome, and mortality in severe traumatic brain injury

Temporal Dynamics of ICP, CPP, PRx, and CPPopt in High-Grade Aneurysmal Subarachnoid Hemorrhage and the Relation to Clinical Outcome

Svedung Wettervik, Teodor; Howells, Timothy; Lewén, Anders; Ronne-Engström, Elisabeth et al.

Ingår i Neurocritical Care, s. 390-402, 2021

• DOI för Temporal Dynamics of ICP, CPP, PRx, and CPPopt in High-Grade Aneurysmal Subarachnoid Hemorrhage and the Relation to Clinical Outcome
• Ladda ner fulltext (pdf) av Temporal Dynamics of ICP, CPP, PRx, and CPPopt in High-Grade Aneurysmal Subarachnoid Hemorrhage and the Relation to Clinical Outcome

Decompressive Craniectomy in Traumatic Brain Injury-Craniectomy-Related and Cranioplasty-Related Complications in a Single Center

Svedung-Wettervik, Teodor; Lenell, Samuel; Enblad, Per; Lewén, Anders

Ingår i World Neurosurgery, 2021

• DOI för Decompressive Craniectomy in Traumatic Brain Injury-Craniectomy-Related and Cranioplasty-Related Complications in a Single Center
• Ladda ner fulltext (pdf) av Decompressive Craniectomy in Traumatic Brain Injury-Craniectomy-Related and Cranioplasty-Related Complications in a Single Center

Variable Temporal Cerebral Blood Flow Response to Acetazolamide in Moyamoya Patients Measured Using Arterial Spin Labeling

Fahlström, Markus; Wikström, Johan; Borota, Ljubisa; Enblad, Per et al.

Ingår i Frontiers in Neurology, 2021

• DOI för Variable Temporal Cerebral Blood Flow Response to Acetazolamide in Moyamoya Patients Measured Using Arterial Spin Labeling
• Ladda ner fulltext (pdf) av Variable Temporal Cerebral Blood Flow Response to Acetazolamide in Moyamoya Patients Measured Using Arterial Spin Labeling

CBF changes and cerebral energy metabolism during hypervolemia, hemodilution, and hypertension therapy in patients with poor-grade subarachnoid hemorrhage

Engquist, Henrik; Lewén, Anders; Hillered, Lars; Ronne-Engström, Elisabeth et al.

Ingår i Journal of Neurosurgery, s. 555-564, 2021

• DOI för CBF changes and cerebral energy metabolism during hypervolemia, hemodilution, and hypertension therapy in patients with poor-grade subarachnoid hemorrhage

Arterial Oxygenation in Traumatic Brain Injury: Relation to Cerebral Energy Metabolism, Autoregulation, and Clinical Outcome

Svedung Wettervik, Teodor; Engquist, Henrik; Howells, Timothy; Lenell, Samuel et al.

Ingår i Journal of Intensive Care Medicine, s. 1075-1083, 2021

• DOI för Arterial Oxygenation in Traumatic Brain Injury: Relation to Cerebral Energy Metabolism, Autoregulation, and Clinical Outcome
• Ladda ner fulltext (pdf) av Arterial Oxygenation in Traumatic Brain Injury: Relation to Cerebral Energy Metabolism, Autoregulation, and Clinical Outcome

Intracranial Pressure Dynamics and Cerebral Vasomotor Reactivity in Coronavirus Disease 2019 Patient With Acute Encephalitis

Svedung-Wettervik, Teodor; Kumlien, Eva; Rostami, Elham; Howells, Timothy et al.

Ingår i ​​​​​Critical Care Explorations, 2020

• DOI för Intracranial Pressure Dynamics and Cerebral Vasomotor Reactivity in Coronavirus Disease 2019 Patient With Acute Encephalitis
• Ladda ner fulltext (pdf) av Intracranial Pressure Dynamics and Cerebral Vasomotor Reactivity in Coronavirus Disease 2019 Patient With Acute Encephalitis

Intracranial pressure-based barbiturate coma treatment in children with refractory intracranial hypertension due to traumatic brain injury

Velle, Fartein; Lewén, Anders; Howells, Timothy; Enblad, Per et al.

Ingår i Journal of Neurosurgery, s. 375-383, 2020

• DOI för Intracranial pressure-based barbiturate coma treatment in children with refractory intracranial hypertension due to traumatic brain injury

Mild hyperventilation in traumatic brain injury: relation to cerebral energy metabolism, pressure autoregulation and clinical outcome

Svedung-Wettervik, Teodor; Howells, Timothy; Hillered, Lars; Nilsson, Pelle et al.

Ingår i World Neurosurgery, 2020

• DOI för Mild hyperventilation in traumatic brain injury: relation to cerebral energy metabolism, pressure autoregulation and clinical outcome

Arterial lactate in traumatic brain injury: Relation to intracranial pressure dynamics, cerebral energy metabolism and clinical outcome

Svedung Wettervik, Teodor; Engquist, Henrik; Howells, Timothy; Rostami, Elham et al.

Ingår i Journal of critical care, s. 218-225, 2020

• DOI för Arterial lactate in traumatic brain injury: Relation to intracranial pressure dynamics, cerebral energy metabolism and clinical outcome

Intracranial pressure variability: relation to clinical outcome, intracranial pressure–volume index, cerebrovascular reactivity and blood pressure variability

Svedung-Wettervik, Teodor; Howells, Timothy; Enblad, Per; Lewén, Anders

Ingår i Journal of clinical monitoring and computing, s. 733-741, 2020

• DOI för Intracranial pressure variability: relation to clinical outcome, intracranial pressure–volume index, cerebrovascular reactivity and blood pressure variability
• Ladda ner fulltext (pdf) av Intracranial pressure variability: relation to clinical outcome, intracranial pressure–volume index, cerebrovascular reactivity and blood pressure variability

High Intravascular Signal Arterial Transit Time Artifacts Have Negligible Effects on Cerebral Blood Flow and Cerebrovascular Reserve Capacity Measurement Using Single Postlabel Delay Arterial Spin-Labeling in Patients with Moyamoya Disease

Fahlström, Markus; Lewén, Anders; Enblad, Per; Larsson, Elna-Marie et al.

Ingår i American Journal of Neuroradiology, s. 430-436, 2020

• DOI för High Intravascular Signal Arterial Transit Time Artifacts Have Negligible Effects on Cerebral Blood Flow and Cerebrovascular Reserve Capacity Measurement Using Single Postlabel Delay Arterial Spin-Labeling in Patients with Moyamoya Disease

Monitoring of Protein Biomarkers of Inflammation in Human Traumatic Brain Injury Using Microdialysis and Proximity Extension Assay Technology in Neurointensive Care

Dyhrfort, Philip; Shen, Qiujin; Clausen, Fredrik; Thulin, Måns et al.

Ingår i Journal of Neurotrauma, s. 2872-2885, 2019

• DOI för Monitoring of Protein Biomarkers of Inflammation in Human Traumatic Brain Injury Using Microdialysis and Proximity Extension Assay Technology in Neurointensive Care
• Ladda ner fulltext (pdf) av Monitoring of Protein Biomarkers of Inflammation in Human Traumatic Brain Injury Using Microdialysis and Proximity Extension Assay Technology in Neurointensive Care

Clinical outcome and prognostic factors in elderly traumatic brain injury patients receiving neurointensive care

Lenell, Samuel; Nyholm, Lena; Lewén, Anders; Enblad, Per

Ingår i Acta Neurochirurgica, s. 1243-1254, 2019

• DOI för Clinical outcome and prognostic factors in elderly traumatic brain injury patients receiving neurointensive care
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Temporal Neurophysiological Dynamics in Traumatic Brain Injury: Role of Pressure Reactivity and Optimal Cerebral Perfusion Pressure for Predicting Outcome

Svedung-Wettervik, Teodor; Howells, Timothy; Enblad, Per; Lewén, Anders

Ingår i Journal of Neurotrauma, s. 1818-1827, 2019

• DOI för Temporal Neurophysiological Dynamics in Traumatic Brain Injury: Role of Pressure Reactivity and Optimal Cerebral Perfusion Pressure for Predicting Outcome

High Arterial Glucose is Associated with Poor Pressure Autoregulation, High Cerebral Lactate/Pyruvate Ratio and Poor Outcome Following Traumatic Brain Injury

Svedung-Wettervik, Teodor; Howells, Timothy; Ronne-Engström, Elisabeth; Hillered, Lars et al.

Ingår i Neurocritical Care, s. 526-533, 2019

• DOI för High Arterial Glucose is Associated with Poor Pressure Autoregulation, High Cerebral Lactate/Pyruvate Ratio and Poor Outcome Following Traumatic Brain Injury
• Ladda ner fulltext (pdf) av High Arterial Glucose is Associated with Poor Pressure Autoregulation, High Cerebral Lactate/Pyruvate Ratio and Poor Outcome Following Traumatic Brain Injury

Intracranial pressure elevations in diffuse axonal injury: association with nonhemorrhagic MR lesions in central mesencephalic structures

Abu Hamdeh, Sami; Marklund, Niklas; Lewén, Anders; Howells, Tim et al.

Ingår i Journal of Neurosurgery, s. 604-611, 2019

• DOI för Intracranial pressure elevations in diffuse axonal injury: association with nonhemorrhagic MR lesions in central mesencephalic structures

Hemodynamic Disturbances in the Early Phase After Subarachnoid Hemorrhage: Regional Cerebral Blood Flow Studied by Bedside Xenon-enhanced CT.

Engquist, Henrik; Lewén, Anders; Howells, Tim; Johnson, Ulf et al.

Ingår i Journal of Neurosurgical Anesthesiology, s. 49-58, 2018

• DOI för Hemodynamic Disturbances in the Early Phase After Subarachnoid Hemorrhage: Regional Cerebral Blood Flow Studied by Bedside Xenon-enhanced CT.

Decompressive craniectomy in traumatic brain injury: usage and clinical outcome in a single centre

Svedung Wettervik, Teodor; Lenell, Samuel; Nyholm, Lena; Howells, Tim et al.

Ingår i Acta Neurochirurgica, s. 229-237, 2018

• DOI för Decompressive craniectomy in traumatic brain injury: usage and clinical outcome in a single centre
• Ladda ner fulltext (pdf) av Decompressive craniectomy in traumatic brain injury: usage and clinical outcome in a single centre

Effect of HHH-Therapy on Regional CBF after Severe Subarachnoid Hemorrhage Studied by Bedside Xenon-Enhanced CT

Engquist, Henrik; Rostami, Elham; Ronne-Engström, Elisabeth; Nilsson, Pelle et al.

Ingår i Neurocritical Care, s. 143-151, 2018

• DOI för Effect of HHH-Therapy on Regional CBF after Severe Subarachnoid Hemorrhage Studied by Bedside Xenon-Enhanced CT
• Ladda ner fulltext (pdf) av Effect of HHH-Therapy on Regional CBF after Severe Subarachnoid Hemorrhage Studied by Bedside Xenon-Enhanced CT

A Dedicated 21-Plex Pea Panel For High-Sensitive Protein Biomarker Detection Using Micro-Dialysis In Traumatic Brain Injury

Lewén, Anders; Dyhrfort, Philip; Clausen, Fredrik; Enblad, Per et al.

Ingår i Journal of Neurotrauma, 2018

Early low cerebral blood flow and high cerebral lactate: prediction of delayed cerebral ischemia in subarachnoid hemorrhage

Rostami, Elham; Engquist, Henrik; Howells, Timothy; Johnson, Ulf et al.

Ingår i Journal of Neurosurgery, s. 1762-1770, 2018

• DOI för Early low cerebral blood flow and high cerebral lactate: prediction of delayed cerebral ischemia in subarachnoid hemorrhage

Dual lumen balloon catheter - An effective substitute for two single lumen catheters in treatment of vascular targets with challenging anatomy

Borota, Ljubisa; Mahmoud, Ehab; Nyberg, Christoffer; Lewén, Anders et al.

Ingår i Journal of clinical neuroscience, s. 91-99, 2018

• DOI för Dual lumen balloon catheter - An effective substitute for two single lumen catheters in treatment of vascular targets with challenging anatomy

The Correlation between Cerebral Blood Flow Measured by Bedside Xenon-CT and Brain Chemistry Monitored by Microdialysis in the Acute Phase following Subarachnoid Hemorrhage

Rostami, Elham; Engquist, Henrik; Howells, Timothy; Ronne-Engström, Elisabeth et al.

Ingår i Frontiers in Neurology, 2017

• DOI för The Correlation between Cerebral Blood Flow Measured by Bedside Xenon-CT and Brain Chemistry Monitored by Microdialysis in the Acute Phase following Subarachnoid Hemorrhage
• Ladda ner fulltext (pdf) av The Correlation between Cerebral Blood Flow Measured by Bedside Xenon-CT and Brain Chemistry Monitored by Microdialysis in the Acute Phase following Subarachnoid Hemorrhage

Increased risk of critical CBF levels in SAH patients with actual CPP below calculated optimal CPP

Johnson, Ulf; Engquist, Henrik; Lewén, Anders; Howells, Tim et al.

Ingår i Acta Neurochirurgica, s. 1065-1071, 2017

• DOI för Increased risk of critical CBF levels in SAH patients with actual CPP below calculated optimal CPP
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The influence of hyperthermia on intracranial pressure, cerebral oximetry and cerebral metabolism in traumatic brain injury

Nyholm, Lena; Howells, Timothy; Lewén, Anders; Hillered, Lars et al.

Ingår i Upsala Journal of Medical Sciences, s. 177-184, 2017

• DOI för The influence of hyperthermia on intracranial pressure, cerebral oximetry and cerebral metabolism in traumatic brain injury
• Ladda ner fulltext (pdf) av The influence of hyperthermia on intracranial pressure, cerebral oximetry and cerebral metabolism in traumatic brain injury

Promising clinical outcome of elderly with TBI after modern neurointensive care

Merzo, Abraham; Lenell, Samuel; Nyholm, Lena; Enblad, Per et al.

Ingår i Acta Neurochirurgica, s. 125-133, 2016

• DOI för Promising clinical outcome of elderly with TBI after modern neurointensive care

Bedside Xenon-CT Shows Lower CBF in SAH Patients with Impaired CBF Pressure Autoregulation as Defined by Pressure Reactivity Index (PRx)

Johnson, Ulf; Engquist, Henrik; Howells, Tim; Nilsson, Pelle et al.

Ingår i Neurocritical Care, s. 47-55, 2016

• DOI för Bedside Xenon-CT Shows Lower CBF in SAH Patients with Impaired CBF Pressure Autoregulation as Defined by Pressure Reactivity Index (PRx)

Positive correlation between occlusion rate and nidus size of proton beam treated brain arteriovenous malformations (AVMs)

Blomquist, Erik; Ronne Engström, Elisabeth; Borota, Ljubisa; Gál, Gyula et al.

Ingår i Acta Oncologica, s. 105-112, 2016

• DOI för Positive correlation between occlusion rate and nidus size of proton beam treated brain arteriovenous malformations (AVMs)

Diffuse traumatic axonal injury in mice induces complex behavioural alterations that are normalized by neutralization of interleukin-1β

Ekmark-Lewén, Sara; Flygt, Johanna; Fridgeirsdottir, Gudrun A.; Kiwanuka, Olivia et al.

Ingår i European Journal of Neuroscience, s. 1016-1033, 2016

• DOI för Diffuse traumatic axonal injury in mice induces complex behavioural alterations that are normalized by neutralization of interleukin-1β

Updated periodic evaluation of standardized neurointensive care shows that it is possible to maintain a high level of favorable outcome even with increasing mean age

Lenell, Samuel; Nyholm, Lena; Lewen, Anders; Enblad, Per

Ingår i Acta Neurochirurgica, s. 417-425, 2015

• DOI för Updated periodic evaluation of standardized neurointensive care shows that it is possible to maintain a high level of favorable outcome even with increasing mean age

Outcome from spontaneous subarachnoid haemorrhage: results from 2007-2011 and comparison with our previous series

Ronne-Engström, Elisabeth; Borota, Ljubisa; Kothimbakam, Raj; Marklund, Niklas et al.

Ingår i Upsala Journal of Medical Sciences, s. 38-43, 2014

• DOI för Outcome from spontaneous subarachnoid haemorrhage: results from 2007-2011 and comparison with our previous series

Cerebral microdialysis for protein biomarker monitoring in the neurointensive care setting - a technical approach

Hillered, Lars; Dahlin, Andreas P; Clausen, Fredrik; Chu, Jiangtao et al.

Ingår i Frontiers in Neurology, s. 245, 2014

• DOI för Cerebral microdialysis for protein biomarker monitoring in the neurointensive care setting - a technical approach
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Monitoring of Cerebral Blood Flow and Metabolism Bedside in Patients with Subarachnoid Hemorrhage - A Xenon-CT and Microdialysis Study

Rostami, Elham; Engquist, Henrik; Johnson, Ulf; Howells, Timothy et al.

Ingår i Frontiers in Neurology, 2014

• DOI för Monitoring of Cerebral Blood Flow and Metabolism Bedside in Patients with Subarachnoid Hemorrhage - A Xenon-CT and Microdialysis Study
• Ladda ner fulltext (pdf) av Monitoring of Cerebral Blood Flow and Metabolism Bedside in Patients with Subarachnoid Hemorrhage - A Xenon-CT and Microdialysis Study

Brain tissue oxygenation and cerebral metabolic patterns in focal and diffuse traumatic brain injury

Purins, Karlis; Lewén, Anders; Hillered, Lars; Howells, Timothy et al.

Ingår i Frontiers in Neurology, 2014

• DOI för Brain tissue oxygenation and cerebral metabolic patterns in focal and diffuse traumatic brain injury
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The Neurological Wake-up Test Does not Alter Cerebral Energy Metabolism and Oxygenation in Patients with Severe Traumatic Brain Injury

Skoglund, Karin; Hillered, Lars; Purins, Karlis; Tsitsopoulos, Parmenion P. et al.

Ingår i Neurocritical Care, s. 413-426, 2014

• DOI för The Neurological Wake-up Test Does not Alter Cerebral Energy Metabolism and Oxygenation in Patients with Severe Traumatic Brain Injury

Should the Neurointensive Care Management of Traumatic Brain Injury Patients be Individualized According to Autoregulation Status and Injury Subtype?

Johnson, Ulf; Lewen, Anders; Ronne-Engström, Elisabeth; Howells, Tim et al.

Ingår i Neurocritical Care, s. 259-265, 2014

• DOI för Should the Neurointensive Care Management of Traumatic Brain Injury Patients be Individualized According to Autoregulation Status and Injury Subtype?

New Microdialysis Method for Protein Biomarker Sampling in the Neurointensive Care Setting

Hillered, Lars; Dahlin, Andreas; Purins, Karlis; Wetterhall, Magnus et al.

Ingår i Journal of Neurotrauma, 2014

Acute neurosurgery for traumatic brain injury by general surgeons in Swedish county hospitals: A regional study

Fischerström, Ann; Nyholm, Lena; Lewen, Anders; Enblad, Per

Ingår i Acta Neurochirurgica, s. 177-185, 2014

• DOI för Acute neurosurgery for traumatic brain injury by general surgeons in Swedish county hospitals: A regional study

Refined microdialysis method for protein biomarker sampling in acute brain injury in the neurointensive care setting

Dahlin, Andreas P; Purins, Karlis; Clausen, Fredrik; Chu, Jiangtao et al.

Ingår i Analytical Chemistry, s. 8671-8679, 2014

• DOI för Refined microdialysis method for protein biomarker sampling in acute brain injury in the neurointensive care setting

Traumatic axonal injury in the mouse is accompanied by a dynamic inflammatory response, astroglial reactivity and complex behavioral changes

Ekmark-Lewén, Sara; Flygt, Johanna; Kiwanuka, Olivia; Meyerson, Bengt et al.

Ingår i Journal of Neuroinflammation, s. 44, 2013

• DOI för Traumatic axonal injury in the mouse is accompanied by a dynamic inflammatory response, astroglial reactivity and complex behavioral changes
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Introduction of the Uppsala Traumatic Brain Injury register for regular surveillance of patient characteristics and neurointensive care management including secondary insult quantification and clinical outcome

Nyholm, Lena; Howells, Tim; Enblad, Per; Lewen, Anders

Ingår i Upsala Journal of Medical Sciences, s. 169-180, 2013

• DOI för Introduction of the Uppsala Traumatic Brain Injury register for regular surveillance of patient characteristics and neurointensive care management including secondary insult quantification and clinical outcome

The use of nurse checklists in a bedside computer-based information system to focus on avoiding secondary insults in neurointensive care

Nyholm, Lena; Lewén, Anders; Fröjd, Camilla; Howells, Tim et al.

Ingår i ISRN Neurology, s. 903954, 2012

• DOI för The use of nurse checklists in a bedside computer-based information system to focus on avoiding secondary insults in neurointensive care

An evaluation of three measures of intracranial compliance in traumatic brain injury patients

Howells, Tim; Lewen, Anders; Sköld, Mattias K.; Ronne-Engström, Elisabeth et al.

Ingår i Intensive Care Medicine, s. 1061-1068, 2012

• DOI för An evaluation of three measures of intracranial compliance in traumatic brain injury patients

Brain Tissue Oxygenation and Cerebral Perfusion Pressure Thresholds of Ischemia in a Standardized Pig Brain Death Model

Purins, Karlis; Enblad, Per; Wiklund, Lars; Lewén, Anders

Ingår i Neurocritical Care, s. 462-469, 2012

• DOI för Brain Tissue Oxygenation and Cerebral Perfusion Pressure Thresholds of Ischemia in a Standardized Pig Brain Death Model

Interstitial F₂-Isoprostane 8-Iso-PGF_2α As a Biomarker of Oxidative Stress after Severe Human Traumatic Brain Injury

Clausen, Fredrik; Marklund, Niklas; Lewén, Anders; Enblad, Per et al.

Ingår i Journal of Neurotrauma, s. 766-775, 2012

• DOI för Interstitial F₂-Isoprostane 8-Iso-PGF_2α As a Biomarker of Oxidative Stress after Severe Human Traumatic Brain Injury

Standardized experimental brain death model for studies of intracranial dynamics, organ preservation, and organ transplantation in the pig

Purins, Karlis; Sedigh, Amir; Molnar, Christian; Jansson, Leif et al.

Ingår i Critical Care Medicine, s. 512-517, 2011

• DOI för Standardized experimental brain death model for studies of intracranial dynamics, organ preservation, and organ transplantation in the pig

Brain tissue oxygen monitoring: a study of in vitro accuracy and stability of Neurovent-PTO and Licox sensors

Purins, Karlis; Enblad, Per; Sandhagen, Bo; Lewén, Anders

Ingår i Acta Neurochirurgica, s. 681-688, 2010

• DOI för Brain tissue oxygen monitoring: a study of in vitro accuracy and stability of Neurovent-PTO and Licox sensors

Vimentin and GFAP responses in astrocytes after contusion trauma to the murine brain

Ekmark-Lewén, Sara; Lewén, Anders; Israelsson, Charlotte; Li, Gui Lin et al.

Ingår i Restorative Neurology and Neuroscience, s. 311-321, 2010

• DOI för Vimentin and GFAP responses in astrocytes after contusion trauma to the murine brain

The Multivariate Concentric Square Field Test Reveals Behavioral Profiles of Risk Taking, Exploration, and Cognitive Impairment in Mice Subjected to Traumatic Brain Injury

Ekmark-Lewén, Sara; Lewén, Anders; Meyerson, Bengt J.; Hillered, Lars

Ingår i Journal of Neurotrauma, s. 1643-1655, 2010

• DOI för The Multivariate Concentric Square Field Test Reveals Behavioral Profiles of Risk Taking, Exploration, and Cognitive Impairment in Mice Subjected to Traumatic Brain Injury

Grafted neural progenitors migrate and form neurons after experimental traumatic brain injury

Wallenquist, Ulrika; Brännvall, Karin; Clausen, Fredrik; Lewén, Anders et al.

Ingår i Restorative Neurology and Neuroscience, s. 323-334, 2009

• DOI för Grafted neural progenitors migrate and form neurons after experimental traumatic brain injury

Distinct cellular patterns of upregulated chemokine expression supporting a prominent inflammatory role in traumatic brain injury

Israelsson, Charlotte; Bengtsson, Henrik; Kylberg, Annika; Kullander, Klas et al.

Ingår i Journal of Neurotrauma, s. 959-974, 2008

• DOI för Distinct cellular patterns of upregulated chemokine expression supporting a prominent inflammatory role in traumatic brain injury

The nitrone free radical scavenger NXY-059 is neuroprotective when administered after traumatic brain injury in the rat

Clausen, Fredrik; Marklund, Niklas; Lewén, Anders; Hillered, Lars

Ingår i Journal of Neurotrauma, s. 1449-1457, 2008

• DOI för The nitrone free radical scavenger NXY-059 is neuroprotective when administered after traumatic brain injury in the rat

T Lymphocyte trafficking: A novel target for neuroprotection in traumatic brain injury

Clausen, Fredrik; Lorant, Tomas; Lewén, Anders; Hillered, Lars

Ingår i Journal of Neurotrauma, s. 1295-1307, 2007

• DOI för T Lymphocyte trafficking: A novel target for neuroprotection in traumatic brain injury

Cerebral glutamine and glutamate levels in relation to compromised energy metabolism: a microdialysis study in subarachnoid hemorrhage patients

Samuelsson, Carolina; Hillered, Lars; Zetterling, Maria; Enblad, Per et al.

Ingår i Journal of Cerebral Blood Flow and Metabolism, s. 1309-1317, 2007

• DOI för Cerebral glutamine and glutamate levels in relation to compromised energy metabolism: a microdialysis study in subarachnoid hemorrhage patients

Genetically modified bone morphogenetic protein signalling alters traumatic brain injury-induced gene expression responses in the adult mouse

Israelsson, Charlotte; Lewén, Anders; Kylberg, Annika; Usoskin, Dmitry et al.

Ingår i Journal of Neuroscience Research, s. 47-57, 2006

• DOI för Genetically modified bone morphogenetic protein signalling alters traumatic brain injury-induced gene expression responses in the adult mouse

Correlation of hippocampal morphological changes and Morris Water Maze performance after cortical contusion injury in rats: Experimental studies

Clausen, Fredrik; Lewén, Anders; Marklund, Niklas; Olsson, Yngve et al.

Ingår i Neurosurgery, s. 154-162, 2005

• DOI för Correlation of hippocampal morphological changes and Morris Water Maze performance after cortical contusion injury in rats: Experimental studies

Oxygen free radical-dependent activation of extracellular signal-regulated kinase mediates apoptosis-like cell death after traumatic brain injury

Clausen, Fredrik; Lundqvist, Hanna; Ekmark, Sara; Lewen, Anders et al.

Ingår i Journal of Neurotrauma, s. 1168-1182, 2004

• DOI för Oxygen free radical-dependent activation of extracellular signal-regulated kinase mediates apoptosis-like cell death after traumatic brain injury

Intracranial pressure elevations in diffuse axonal injury are associated with non-hemorrhagic MR lesions in central mesencephalic structures

Abu Hamdeh, Sami; Marklund, Niklas; Lewén, Anders; Howells, Timothy et al.

Akuta vaskulära neurokirurgiska tillstånd kräver snabb hantering: [Considerations when handling common acute intracranial vascular anomalies]

Tobieson, Lovisa; Samuelsson, Jennifer; Lewén, Anders; Kronvall, Erik et al.

Ingår i Läkartidningen, 2023

Cerebral Pressure Autoregulation in Brain Injury and Disorders: A Review on Monitoring, Management, and Future Directions

Svedung Wettervik, Teodor; Fahlström, Markus; Enblad, Per; Lewén, Anders

Ingår i World Neurosurgery, s. 118-131, 2022

• DOI för Cerebral Pressure Autoregulation in Brain Injury and Disorders: A Review on Monitoring, Management, and Future Directions
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Fine Tuning of Traumatic Brain Injury Management in Neurointensive Care-Indicative Observations and Future Perspectives

Svedung-Wettervik, Teodor; Lewén, Anders; Enblad, Per

Ingår i Frontiers in Neurology, 2021

• DOI för Fine Tuning of Traumatic Brain Injury Management in Neurointensive Care-Indicative Observations and Future Perspectives
• Ladda ner fulltext (pdf) av Fine Tuning of Traumatic Brain Injury Management in Neurointensive Care-Indicative Observations and Future Perspectives

Phantom-based evaluation of a planar microwave sensor for non-invasive intracranial pressure monitoring

Perez, Mauricio D.; Avetisyan, Erik; Mandal, Bappaditya; Monorchio, Agostino et al.

Ingår i 2023 IEEE MTT-S International Microwave Biomedical Conference, IMBioC, s. 1-3, 2023

• DOI för Phantom-based evaluation of a planar microwave sensor for non-invasive intracranial pressure monitoring

A Four-Layer Phantom for Testing In-Vitro Microwave-Based Sensing Approach in Intra-Cranial Pressure Monitoring

Velander, Jacob; Redzwan, Syaiful; Perez, Mauricio D.; Asan, Noor Badariah et al.

Ingår i Proceedings Of The 2018 IEEE/MTT-S International Microwave Biomedical Conference (IMBioC), s. 49-51, 2018

• DOI för A Four-Layer Phantom for Testing In-Vitro Microwave-Based Sensing Approach in Intra-Cranial Pressure Monitoring

Initial In-Vitro Trial for Intra-Cranial Pressure Monitoring Using Subdermal Proximity-Coupled Split-Ring Resonator

Redzwan, Syaiful; Velander, Jacob; Perez, Mauricio D.; Asan, Noor Badariah et al.

Ingår i Proceedings of the 2018 IEEE/MTT-S International Microwave Biomedical Conference (IMBioC), s. 73-75, 2018

• DOI för Initial In-Vitro Trial for Intra-Cranial Pressure Monitoring Using Subdermal Proximity-Coupled Split-Ring Resonator

Improved Microdialysis Sampling of Proteins using Surface Modified Catheters: An in vivo Study in Standardized Pig Brain Death Model

Dahlin, Andreas P; Purins, Karlis; Lewen, Anders; Hillered, Lars

2013

Decreased T-lymphocyte response to T-cell-dependent vaccines after neurotrauma or neurosurgery

Ljunghill Hedberg, Anna; Berglund, Sofia; Wilske, Frida; Enblad, Per et al.

Cerebrovascular reactivity (PRx) and optimal cerebral perfusion pressure in elderly with traumatic brain injury.

Lenell, Samuel; Svedung-Wettervik, Teodor; Howells, Timothy; Hånell, Anders et al.

Predicting ordinal GOSE using dynamic ICU physiological variables in moderate-to-severe TBI: A Temporal and Stratified Split Study

Bark, David; Hult, Ludvig; Hånell, Anders; Svedung-Wettervik, Teodor et al.