Fredrik Pontén
- Telephone:
- +46 18 611 38 46
- Mobile phone:
- +46 70 309 23 42
- E-mail:
- fredrik.ponten@igp.uu.se
- Visiting address:
- Dag Hammarskjölds väg 20
751 85 Uppsala - Postal address:
- Rudbecklaboratoriet
751 85 UPPSALA
Biography
Fredrik Ponten, MD, PhD, is Professor at Uppsala University and a board-certified specialist of Anatomical Pathology at the Uppsala University Hospital. He is the Vice-Program Director and Clinical Director of the Human Protein Atlas program, and heads the Human Protein Atlas effort at the Uppsala site. His research is based on an affinity proteomics approach with emphasis on translational medicine. Dr Ponten who is a former Fulbright schollar, is one of the founders of the Human Protein Atlas program and a member of the Atlas Antibodies AB Board. Dr Ponten received his PhD from Uppsala University in 1996, he did a post-doc at Yale University (New Haven, CT, USA) and became full professor in 2008 at the Department of Immunology, Genetics and Pathology, Uppsala University, Sweden.

Publications
Selection of publications
A subcellular map of the human proteome
Part of Science, 2017
A pathology atlas of the human cancer transcriptome
Part of Science, 2017
Expression of Human Skin-Specific Genes Defined by Transcriptomics and Antibody-Based Profiling
Part of Journal of Histochemistry and Cytochemistry, p. 129-141, 2015
Tissue-based map of the human proteome
Part of Science, p. 394-+, 2015
A systematic analysis of commonly used antibodies in cancer diagnostics
Part of Histopathology, p. 293-305, 2014
The Human Protein Atlas as a proteomic resource for biomarker discovery
Part of Journal of Internal Medicine, p. 428-446, 2011
Recent publications
Prognostic genome and transcriptome signatures in colorectal cancers
Part of Nature, p. 137-146, 2024
Part of Journal of the Endocrine Society, 2024
- DOI for Transcriptome Analysis Reveals Distinct Patterns Between the Invasive and Noninvasive Pituitary Neuroendocrine Tumors
- Download full text (pdf) of Transcriptome Analysis Reveals Distinct Patterns Between the Invasive and Noninvasive Pituitary Neuroendocrine Tumors
Part of Journal of Surgical Oncology, p. 734-744, 2024
CD93 maintains endothelial barrier function and limits metastatic dissemination
Part of JCI Insight, 2024
- DOI for CD93 maintains endothelial barrier function and limits metastatic dissemination
- Download full text (pdf) of CD93 maintains endothelial barrier function and limits metastatic dissemination
A human stomach cell type transcriptome atlas
Part of BMC Biology, 2024
- DOI for A human stomach cell type transcriptome atlas
- Download full text (pdf) of A human stomach cell type transcriptome atlas
All publications
Articles in journal
Prognostic genome and transcriptome signatures in colorectal cancers
Part of Nature, p. 137-146, 2024
Part of Journal of the Endocrine Society, 2024
- DOI for Transcriptome Analysis Reveals Distinct Patterns Between the Invasive and Noninvasive Pituitary Neuroendocrine Tumors
- Download full text (pdf) of Transcriptome Analysis Reveals Distinct Patterns Between the Invasive and Noninvasive Pituitary Neuroendocrine Tumors
Part of Journal of Surgical Oncology, p. 734-744, 2024
CD93 maintains endothelial barrier function and limits metastatic dissemination
Part of JCI Insight, 2024
- DOI for CD93 maintains endothelial barrier function and limits metastatic dissemination
- Download full text (pdf) of CD93 maintains endothelial barrier function and limits metastatic dissemination
A human stomach cell type transcriptome atlas
Part of BMC Biology, 2024
- DOI for A human stomach cell type transcriptome atlas
- Download full text (pdf) of A human stomach cell type transcriptome atlas
Effect of preoperative chemotherapy on the histopathological classification of gastric cancer
Part of Gastric Cancer, p. 102-109, 2024
- DOI for Effect of preoperative chemotherapy on the histopathological classification of gastric cancer
- Download full text (pdf) of Effect of preoperative chemotherapy on the histopathological classification of gastric cancer
Part of EJNMMI Radiopharmacy and Chemistry, 2023
- DOI for Imaging of fibrogenesis in the liver by [18F]TZ-Z09591, an Affibody molecule targeting platelet derived growth factor receptor β
- Download full text (pdf) of Imaging of fibrogenesis in the liver by [18F]TZ-Z09591, an Affibody molecule targeting platelet derived growth factor receptor β
Spatial immunophenotyping of the tumour microenvironment in non-small cell lung cancer
Part of European Journal of Cancer, p. 40-52, 2023
- DOI for Spatial immunophenotyping of the tumour microenvironment in non-small cell lung cancer
- Download full text (pdf) of Spatial immunophenotyping of the tumour microenvironment in non-small cell lung cancer
Absolute Quantification of Pan-Cancer Plasma Proteomes Reveals Unique Signature in Multiple Myeloma
Part of Cancers, 2023
- DOI for Absolute Quantification of Pan-Cancer Plasma Proteomes Reveals Unique Signature in Multiple Myeloma
- Download full text (pdf) of Absolute Quantification of Pan-Cancer Plasma Proteomes Reveals Unique Signature in Multiple Myeloma
Next generation pan-cancer blood proteome profiling using proximity extension assay
Part of Nature Communications, 2023
- DOI for Next generation pan-cancer blood proteome profiling using proximity extension assay
- Download full text (pdf) of Next generation pan-cancer blood proteome profiling using proximity extension assay
Part of EBioMedicine, 2023
- DOI for An immune score reflecting pro- and anti-tumoural balance of tumour microenvironment has major prognostic impact and predicts immunotherapy response in solid cancers
- Download full text (pdf) of An immune score reflecting pro- and anti-tumoural balance of tumour microenvironment has major prognostic impact and predicts immunotherapy response in solid cancers
Combined expression of HOXA11 and CD10 identifies endometriosis versus normal tissue and tumors
Part of Annals of Diagnostic Pathology, 2022
- DOI for Combined expression of HOXA11 and CD10 identifies endometriosis versus normal tissue and tumors
- Download full text (pdf) of Combined expression of HOXA11 and CD10 identifies endometriosis versus normal tissue and tumors
Genome-wide annotation of protein-coding genes in pig
Part of BMC Biology, 2022
- DOI for Genome-wide annotation of protein-coding genes in pig
- Download full text (pdf) of Genome-wide annotation of protein-coding genes in pig
A human adipose tissue cell-type transcriptome atlas
Part of Cell Reports, 2022
- DOI for A human adipose tissue cell-type transcriptome atlas
- Download full text (pdf) of A human adipose tissue cell-type transcriptome atlas
Part of Nature Communications, 2022
- DOI for Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level
- Download full text (pdf) of Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level
Part of Journal of Pathology, p. 243-256, 2021
- DOI for Infiltration of NK and plasma cells is associated with a distinct immune subset in non‐small cell lung cancer
- Download full text (pdf) of Infiltration of NK and plasma cells is associated with a distinct immune subset in non‐small cell lung cancer
A single-cell type transcriptomics map of human tissues
Part of Science Advances, 2021
- DOI for A single-cell type transcriptomics map of human tissues
- Download full text (pdf) of A single-cell type transcriptomics map of human tissues
Part of Neuro-Oncology, p. 398-411, 2021
- DOI for ELTD1-deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma.
- Download full text (pdf) of ELTD1-deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma.
Part of Oncogene, p. 3748-3765, 2021
- DOI for The noncoding MIR100HG RNA enhances the autocrine function of transforming growth factor beta signaling
- Download full text (pdf) of The noncoding MIR100HG RNA enhances the autocrine function of transforming growth factor beta signaling
Spatiotemporal dissection of the cell cycle with single-cell proteogenomics
Part of Nature, p. 649-654, 2021
Part of EBioMedicine, 2021
- DOI for The prognostic impact of the tumour stroma fraction: A machine learning-based analysis in 16 human solid tumour types
- Download full text (pdf) of The prognostic impact of the tumour stroma fraction: A machine learning-based analysis in 16 human solid tumour types
Annotation of pituitary neuroendocrine tumors with genome-wide expression analysis
Part of Acta neuropathologica communications, 2021
The Immune Landscape of Colorectal Cancer
Part of Cancers, 2021
- DOI for The Immune Landscape of Colorectal Cancer
- Download full text (pdf) of The Immune Landscape of Colorectal Cancer
Part of Acta Oncologica, p. 417-426, 2020
- DOI for Molecular characterization of a large unselected cohort of metastatic colorectal cancers in relation to primary tumor location, rare metastatic sites and prognosis
- Download full text (pdf) of Molecular characterization of a large unselected cohort of metastatic colorectal cancers in relation to primary tumor location, rare metastatic sites and prognosis
An atlas of the protein-coding genes in the human, pig, and mouse brain
Part of Science, p. 1090-+, 2020
Part of Frontiers in Oncology, 2020
- DOI for CDX2: A Prognostic Marker in Metastatic Colorectal Cancer Defining a Better BRAF Mutated and a Worse KRAS Mutated Subgroup
- Download full text (pdf) of CDX2: A Prognostic Marker in Metastatic Colorectal Cancer Defining a Better BRAF Mutated and a Worse KRAS Mutated Subgroup
Part of Acta Oncologica, p. 284-290, 2020
- DOI for Metastatic colorectal carcinomas with high SATB2 expression are associated with better prognosis and response to chemotherapy: a population-based Scandinavian study
- Download full text (pdf) of Metastatic colorectal carcinomas with high SATB2 expression are associated with better prognosis and response to chemotherapy: a population-based Scandinavian study
Proximity Ligation Assay as a Tool for Antibody Validation in Human Tissues
Part of Journal of Histochemistry and Cytochemistry, p. 515-529, 2020
Blood-derived biomarkers correlate with clinical progression in Duchenne muscular dystrophy
Part of JOURNAL OF NEUROMUSCULAR DISEASES, p. 231-246, 2020
- DOI for Blood-derived biomarkers correlate with clinical progression in Duchenne muscular dystrophy
- Download full text (pdf) of Blood-derived biomarkers correlate with clinical progression in Duchenne muscular dystrophy
Part of Science Signaling, 2019
A deep proteome and transcriptome abundance atlas of 29 healthy human tissues
Part of Molecular Systems Biology, 2019
- DOI for A deep proteome and transcriptome abundance atlas of 29 healthy human tissues
- Download full text (pdf) of A deep proteome and transcriptome abundance atlas of 29 healthy human tissues
Quantification and discovery of sequence determinants of protein-per-mRNA amount in 29 human tissues
Part of Molecular Systems Biology, 2019
- DOI for Quantification and discovery of sequence determinants of protein-per-mRNA amount in 29 human tissues
- Download full text (pdf) of Quantification and discovery of sequence determinants of protein-per-mRNA amount in 29 human tissues
Part of Cancer Medicine, p. 3623-3635, 2019
- DOI for Consequences of a high incidence of microsatellite instability and BRAF-mutated tumors: A population-based cohort of metastatic colorectal cancer patients
- Download full text (pdf) of Consequences of a high incidence of microsatellite instability and BRAF-mutated tumors: A population-based cohort of metastatic colorectal cancer patients
Part of Journal of Cancer, p. 3224-3231, 2019
- DOI for Tumoral pyruvate kinase L/R as a predictive marker for the treatment of renal cancer patients with sunitinib and sorafenib
- Download full text (pdf) of Tumoral pyruvate kinase L/R as a predictive marker for the treatment of renal cancer patients with sunitinib and sorafenib
Systematic assessment of antibody selectivity in plasma based on a resource of enrichment profiles
Part of Scientific Reports, 2019
- DOI for Systematic assessment of antibody selectivity in plasma based on a resource of enrichment profiles
- Download full text (pdf) of Systematic assessment of antibody selectivity in plasma based on a resource of enrichment profiles
A genome-wide transcriptomic analysis of protein-coding genes in human blood cells
Part of Science, p. 1471-+, 2019
LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer
Part of International Journal of Cancer, p. 901-915, 2019
- DOI for LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer
- Download full text (pdf) of LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer
Part of Journal of Thoracic Oncology, p. 628-640, 2019
- DOI for Prognostic Impact of Tumor Cell Programmed Death Ligand 1 Expression and Immune Cell Infiltration in NSCLC
- Download full text (pdf) of Prognostic Impact of Tumor Cell Programmed Death Ligand 1 Expression and Immune Cell Infiltration in NSCLC
Part of British Journal of Cancer, p. 303-311, 2019
Mining the Human Tissue Proteome for Protein Citrullination
Part of Molecular & Cellular Proteomics, p. 1378-1391, 2018
Part of Acta Oncologica, p. 187-194, 2018
- DOI for U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.
- Download full text (pdf) of U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.
Part of Gynecologic Oncology, p. 173-180, 2018
Part of JACC-BASIC TO TRANSLATIONAL SCIENCE, p. 464-480, 2018
- DOI for Novel Multiomics Profiling of Human Carotid Atherosclerotic Plaques and Plasma Reveals Biliverdin Reductase B as a Marker of Intraplaque Hemorrhage
- Download full text (pdf) of Novel Multiomics Profiling of Human Carotid Atherosclerotic Plaques and Plasma Reveals Biliverdin Reductase B as a Marker of Intraplaque Hemorrhage
Part of Pituitary, p. 443-443, 2018
Detection of autoantibodies against cancer-testis antigens in non-small cell lung cancer
Part of Lung Cancer, p. 157-163, 2018
Part of Modern Pathology, p. 253-263, 2018
Part of Modern Pathology, p. 964-977, 2017
Part of BMC Cancer, 2017
- DOI for A systematic search strategy identifies cubilin as independent prognostic marker for renal cell carcinoma
- Download full text (pdf) of A systematic search strategy identifies cubilin as independent prognostic marker for renal cell carcinoma
Part of Frontiers in Oncology, 2017
- DOI for Mast Cell Infiltration in Human Brain Metastases Modulates the Microenvironment and Contributes to the Metastatic Potential
- Download full text (pdf) of Mast Cell Infiltration in Human Brain Metastases Modulates the Microenvironment and Contributes to the Metastatic Potential
Part of Oncotarget, p. 24815-24827, 2017
- DOI for Serglycin as a potential biomarker for glioma: association of serglycin expression, extent of mast cell recruitment and glioblastoma progression
- Download full text (pdf) of Serglycin as a potential biomarker for glioma: association of serglycin expression, extent of mast cell recruitment and glioblastoma progression
Tumoral ANXA1 Is a Predictive Marker for Sunitinib Treatment of Renal Cancer Patients
Part of Journal of Cancer, p. 3975-3983, 2017
- DOI for Tumoral ANXA1 Is a Predictive Marker for Sunitinib Treatment of Renal Cancer Patients
- Download full text (pdf) of Tumoral ANXA1 Is a Predictive Marker for Sunitinib Treatment of Renal Cancer Patients
Part of Acta Neuropathologica, p. 675-677, 2017
A subcellular map of the human proteome
Part of Science, 2017
Part of PLOS ONE, 2017
- DOI for High RBM3 expression is associated with an improved survival and oxaliplatin response in patients with metastatic colorectal cancer
- Download full text (pdf) of High RBM3 expression is associated with an improved survival and oxaliplatin response in patients with metastatic colorectal cancer
Part of Journal of Cancer Research and Clinical Oncology, p. 961-970, 2017
- DOI for Tumoral cubilin is a predictive marker for treatment of renal cancer patients with sunitinib and sorafenib
- Download full text (pdf) of Tumoral cubilin is a predictive marker for treatment of renal cancer patients with sunitinib and sorafenib
The human adrenal gland proteome defined by transcriptomics and antibody-based profiling
Part of Endocrinology, p. 239-251, 2017
Part of American Journal of Surgical Pathology, p. 1238-1246, 2017
A pathology atlas of the human cancer transcriptome
Part of Science, 2017
Part of Clinical Genetics, p. 510-516, 2017
Principles of Systems Biology, No. 21: Editorial
Part of CELL SYSTEMS, p. 158-160, 2017
Part of Journal of Oral Pathology & Medicine, p. 717-724, 2017
Breast cancer in young women and prognosis: How important are proliferation markers?
Part of European Journal of Cancer, p. 278-289, 2017
Part of Translational Oncology, p. 385-395, 2017
Part of Thrombosis and Haemostasis, p. 1050-1059, 2016
Inconsistent results in the analysis of ALK rearrangements in non-small cell lung cancer
Part of BMC Cancer, 2016
- DOI for Inconsistent results in the analysis of ALK rearrangements in non-small cell lung cancer
- Download full text (pdf) of Inconsistent results in the analysis of ALK rearrangements in non-small cell lung cancer
Part of BMC Cancer, 2016
- DOI for ANLN is a prognostic biomarker independent of Ki-67 and essential for cell cycle progression in primary breast cancer
- Download full text (pdf) of ANLN is a prognostic biomarker independent of Ki-67 and essential for cell cycle progression in primary breast cancer
Part of Oncotarget, p. 72431-72442, 2016
- DOI for PROX1 is a novel pathway-specific prognostic biomarker for high-grade astrocytomas; results from independent glioblastoma cohorts stratified by age and IDH mutation status.
- Download full text (pdf) of PROX1 is a novel pathway-specific prognostic biomarker for high-grade astrocytomas; results from independent glioblastoma cohorts stratified by age and IDH mutation status.
Survival-associated heterogeneity of marker-defined perivascular cells in colorectal cancer
Part of Oncotarget, p. 41948-41958, 2016
GPR44 is a pancreatic protein restricted to the human beta cell
Part of Acta Diabetologica, p. 413-421, 2016
SATB2 is expressed in Merkel cell carcinoma
Part of Archives of Dermatological Research, p. 449-454, 2016
Long-term outcome in young women with breast cancer: a population-based study
Part of Breast Cancer Research and Treatment, p. 131-143, 2016
- DOI for Long-term outcome in young women with breast cancer: a population-based study
- Download full text (pdf) of Long-term outcome in young women with breast cancer: a population-based study
Part of Cancer Research, p. 3166-3178, 2016
Profiling cancer testis antigens in non-small-cell lung cancer
Part of JCI INSIGHT, 2016
Part of Journal of Neurosurgery, p. 1155-1166, 2016
The protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene
Part of Science Translational Medicine, 2016
System-wide Clinical Proteomics of Breast Cancer Reveals Global Remodeling of Tissue Homeostasis
Part of CELL SYSTEMS, p. 172-184, 2016
Analysis of Body-wide Unfractionated Tissue Data to Identify a Core Human Endothelial Transcriptome.
Part of Cell systems, p. 287-301000, 2016
Visualization and analysis of gene expression in tissue sections by spatial transcriptomics
Part of Science, p. 78-82, 2016
Oncogene-Induced Senescence in Pituitary Adenomas-an Immunohistochemical Study.
Part of Endocrine pathology, p. 1-11, 2016
Gene-specific correlation of RNA and protein levels in human cells and tissues
Part of Molecular Systems Biology, 2016
- DOI for Gene-specific correlation of RNA and protein levels in human cells and tissues
- Download full text (pdf) of Gene-specific correlation of RNA and protein levels in human cells and tissues
Part of Nucleic Acids Research, p. 6787-6798, 2015
- DOI for Complementing tissue characterization by integrating transcriptome profiling from the Human Protein Atlas and from the FANTOM5 consortium
- Download full text (pdf) of Complementing tissue characterization by integrating transcriptome profiling from the Human Protein Atlas and from the FANTOM5 consortium
Part of PLOS ONE, 2015
- DOI for The Urinary Bladder Transcriptome and Proteome Defined by Transcriptomics and Antibody-Based Profiling
- Download full text (pdf) of The Urinary Bladder Transcriptome and Proteome Defined by Transcriptomics and Antibody-Based Profiling
A Tissue-Based Map of the Human Proteome
Part of Scandinavian Journal of Immunology, p. 329-329, 2015
Part of PLOS ONE, 2015
- DOI for Defining the Human Brain Proteome Using Transcriptomics and Antibody-Based Profiling with a Focus on the Cerebral Cortex
- Download full text (pdf) of Defining the Human Brain Proteome Using Transcriptomics and Antibody-Based Profiling with a Focus on the Cerebral Cortex
Part of Gynecologic Oncology, p. 529-537, 2015
Expression of Human Skin-Specific Genes Defined by Transcriptomics and Antibody-Based Profiling
Part of Journal of Histochemistry and Cytochemistry, p. 129-141, 2015
The Human Endometrium-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling
Part of Omics, p. 659-668, 2015
Part of Nature Medicine, p. 741-+, 2015
Part of BMC Genomics, 2015
- DOI for The human cardiac and skeletal muscle proteomes defined by transcriptomics and antibody-based profiling
- Download full text (pdf) of The human cardiac and skeletal muscle proteomes defined by transcriptomics and antibody-based profiling
Part of Oncotarget, p. 23647-23661, 2015
- DOI for Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells
- Download full text (pdf) of Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells
Part of Journal of Thoracic Oncology, 2015
Part of Science Signaling, 2015
Part of American Journal of Pathology, p. 1600-1609, 2015
Part of Journal of gastroenterology, p. 46-57, 2015
Part of International Journal of Cancer, p. 1608-1618, 2015
Part of PLOS ONE, 2015
- DOI for Analysis of the Human Prostate-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling Identifies TMEM79 and ACOXL as Two Putative, Diagnostic Markers in Prostate Cancer
- Download full text (pdf) of Analysis of the Human Prostate-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling Identifies TMEM79 and ACOXL as Two Putative, Diagnostic Markers in Prostate Cancer
Part of PLOS ONE, 2015
Part of Experimental Cell Research, p. 280-288, 2015
Part of Cancer Letters, p. 837-845, 2015
Part of Journal of Thoracic Oncology, 2015
Part of Journal of Thoracic Oncology, 2015
FGF2 as a potential prognostic biomarker for proneural glioma patients
Part of Acta Oncologica, p. 385-394, 2015
Part of Developmental Cell, p. 19-32, 2015
Tissue-based map of the human proteome
Part of Science, p. 394-+, 2015
Part of Cancer Research, p. 4504-4516, 2015
Defining the human gallbladder proteome by transcriptomics and affinity proteomics
Part of Proteomics, p. 2498-2507, 2014
Defining the Human Adipose Tissue Proteome To Reveal Metabolic Alterations in Obesity
Part of Journal of Proteome Research, p. 5106-5119, 2014
Breast cancer in young women - age a risk factor only in those not given chemotherapy
Part of Breast, 2014
Part of EMBO Molecular Medicine, p. 918-936, 2014
Decreased decorin expression in the tumor microenvironment
Part of Cancer Medicine, p. 485-491, 2014
Part of Breast Cancer Research, 2014
- DOI for Peroxiredoxin-1 protects estrogen receptor alpha from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer
- Download full text (pdf) of Peroxiredoxin-1 protects estrogen receptor alpha from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer
Part of Molecular Oncology, p. 50-58, 2014
WNT5A-mediated β-catenin-independent signalling is a novel regulator of cancer cell metabolism
Part of Carcinogenesis, p. 784-794, 2014
Part of Diabetologia, p. 645-646, 2014
Part of Tumor Biology, p. 4479-4488, 2014
The Kidney Transcriptome and Proteome Defined by Transcriptomics and Antibody-Based Profiling
Part of PLOS ONE, 2014
- DOI for The Kidney Transcriptome and Proteome Defined by Transcriptomics and Antibody-Based Profiling
- Download full text (pdf) of The Kidney Transcriptome and Proteome Defined by Transcriptomics and Antibody-Based Profiling
The Human Pancreas Proteome Defined by Transcriptomics and Antibody-Based Profiling
Part of PLOS ONE, 2014
- DOI for The Human Pancreas Proteome Defined by Transcriptomics and Antibody-Based Profiling
- Download full text (pdf) of The Human Pancreas Proteome Defined by Transcriptomics and Antibody-Based Profiling
Aberrantly activated claudin 6 and 18.2 as potential therapy targets in non-small-cell lung cancer
Part of International Journal of Cancer, p. 2206-2214, 2014
Part of PLOS ONE, 2014
- DOI for Human cytomegalovirus tegument protein pp65 is detected in all intra- and extra-axial brain tumours independent of the tumour type or grade
- Download full text (pdf) of Human cytomegalovirus tegument protein pp65 is detected in all intra- and extra-axial brain tumours independent of the tumour type or grade
Part of American Journal of Clinical Pathology, p. 630-638, 2014
The human testis-specific proteome defined by transcriptomics and antibody-based profiling
Part of Molecular human reproduction, p. 476-488, 2014
The lung-specific proteome defined by integration of transcriptomics and antibody-based profiling
Part of The FASEB Journal, p. 5184-5196, 2014
A systematic analysis of commonly used antibodies in cancer diagnostics
Part of Histopathology, p. 293-305, 2014
Part of Circulation Heart Failure, p. 359-366, 2014
Part of Methods, p. 34-38, 2014
- DOI for Antibody validation of immunohistochemistry for biomarker discovery: Recommendations of a consortium of academic and pharmaceutical based histopathology researchers
- Download full text (pdf) of Antibody validation of immunohistochemistry for biomarker discovery: Recommendations of a consortium of academic and pharmaceutical based histopathology researchers
The human liver-specific proteome defined by transcriptomics and antibody-based profiling
Part of The FASEB Journal, p. 2901-2914, 2014
Analysis of Candidate Genes for Lineage-Specific Expression Changes in Humans and Primates
Part of Journal of Proteome Research, p. 3596-3606, 2014
Part of International Journal of Cancer, p. 1123-1131, 2014
Subtyping of gliomas of various WHO grades by the application of immunohistochemistry
Part of Histopathology, p. 365-379, 2014
Colorectal cancer candidate biomarkers identified by tissue secretome proteome profiling
Part of Journal of Proteomics, p. 26-39, 2014
Antibody performance in western blot applications is context-dependent
Part of Biotechnology Journal, p. 435-445, 2014
Part of Journal of the Royal Society of Medicine, p. 22-29, 2014
Part of Human Pathology, p. 382-393, 2014
Part of Molecular & Cellular Proteomics, p. 397-406, 2014
Investigation of molecular alterations of AKT-3 in triple-negative breast cancer
Part of Histopathology, p. 660-670, 2014
Part of Journal of Proteome Research, p. 2439-2448, 2013
Part of BMC Cancer, 2013
- DOI for Systematic antibody generation and validation via tissue microarray technology leading to identification of a novel protein prognostic panel in breast cancer
- Download full text (pdf) of Systematic antibody generation and validation via tissue microarray technology leading to identification of a novel protein prognostic panel in breast cancer
In situ Protein Detection for Companion Diagnostics
Part of Frontiers in Oncology, 2013
Part of Cancer Letters, p. 222-228, 2013
Vandetanib combined with a p38 MAPK inhibitor synergistically reduces glioblastoma cell survival
Part of Medical Oncology, p. 638, 2013
Part of Clinical Cancer Research, p. 194-204, 2013
Part of Cancer Research, 2013
European H16N3 Gull Influenza Virus Attaches to the Human Respiratory Tract and Eye
Part of PLOS ONE, 2013
- DOI for European H16N3 Gull Influenza Virus Attaches to the Human Respiratory Tract and Eye
- Download full text (pdf) of European H16N3 Gull Influenza Virus Attaches to the Human Respiratory Tract and Eye
Part of PLOS ONE, 2013
- DOI for A Texture Based Pattern Recognition Approach to Distinguish Melanoma from Non-Melanoma Cells in Histopathological Tissue Microarray Sections
- Download full text (pdf) of A Texture Based Pattern Recognition Approach to Distinguish Melanoma from Non-Melanoma Cells in Histopathological Tissue Microarray Sections
The protein phosphatase 2 subunit PR48 is a novel melanoma tumor suppressor gene.
Part of Cancer Research, 2013
Increased expression of heparanase in symptomatic carotid atherosclerosis
Part of Atherosclerosis, p. 67-73, 2013
Part of Journal of Pathology, p. 719-728, 2013
Part of Gastroenterology, p. 1001-1011, 2013
Estrogen receptor expression induces changes in the microRNA pool in human colon cancer cells
Part of Carcinogenesis, p. 1431-1441, 2013
Part of Neuroendocrinology, p. 16-30, 2013
Part of Gynecologic Oncology, p. 463-469, 2013
Part of Arteriosclerosis, Thrombosis and Vascular Biology, p. 2432-2443, 2013
Part of Journal of Histochemistry and Cytochemistry, p. 773-784, 2013
Part of EMBO Molecular Medicine, p. 1067-1086, 2013
- DOI for CDK-mediated activation of the SCFFBXO28 ubiquitin ligase promotes MYC-driven transcription and tumourigenesis and predicts poor survival in breast cancer
- Download full text (pdf) of CDK-mediated activation of the SCFFBXO28 ubiquitin ligase promotes MYC-driven transcription and tumourigenesis and predicts poor survival in breast cancer
Part of Proceedings of the National Academy of Sciences of the United States of America, p. 6853-6858, 2013
Novel signatures of cancer-associated fibroblasts
Part of International Journal of Cancer, p. 286-293, 2013
Part of International Journal of Gynecological Cancer, 2013
Part of Journal of Visualized Experiments, 2012
- DOI for Production of tissue microarrays, immunohistochemistry staining and digitalization within the human protein atlas
- Download full text (pdf) of Production of tissue microarrays, immunohistochemistry staining and digitalization within the human protein atlas
Part of BMC Cancer, p. 306, 2012
- DOI for The presence of tumor associated macrophages in tumor stroma as a prognostic marker for breast cancer patients
- Download full text (pdf) of The presence of tumor associated macrophages in tumor stroma as a prognostic marker for breast cancer patients
Part of BMC Medicine, p. 103, 2012
- DOI for A tool to facilitate clinical biomarker studies - a tissue dictionary based on the Human Protein Atlas
- Download full text (pdf) of A tool to facilitate clinical biomarker studies - a tissue dictionary based on the Human Protein Atlas
CD99 is a novel prognostic stromal marker in non-small cell lung cancer
Part of International Journal of Cancer, p. 2264-2273, 2012
Part of Journal of Pathology, p. 378-390, 2012
Part of Developmental Dynamics, p. 770-786, 2012
Part of PLOS ONE, 2012
- DOI for Scalable In Situ Hybridization on Tissue Arrays for Validation of Novel Cancer and Tissue-Specific Biomarkers
- Download full text (pdf) of Scalable In Situ Hybridization on Tissue Arrays for Validation of Novel Cancer and Tissue-Specific Biomarkers
Part of PLOS ONE, 2012
- DOI for GABA-A Channel Subunit Expression in Human Glioma Correlates with Tumor Histology and Clinical Outcome
- Download full text (pdf) of GABA-A Channel Subunit Expression in Human Glioma Correlates with Tumor Histology and Clinical Outcome
Part of Journal of Pathology, p. 442-450, 2012
Antibody-based Protein Profiling of the Human Chromosome 21
Part of Molecular & Cellular Proteomics, 2012
TPX2 and AURKA promote 20q amplicon-driven colorectal adenoma to carcinoma progression
Part of Gut, p. 1568-1575, 2012
Part of Gut, p. 855-864, 2012
Part of Journal of Proteomics, p. 2611-2620, 2012
CSE1L, DIDO1 and RBM39 in colorectal adenoma to carcinoma progression
Part of Cellular Oncology, p. 293-300, 2012
Part of European Journal of Cancer, 2012
SATB2 is an Independent Predictor of Outcome in Colorectal Cancer
Part of European Journal of Cancer, 2012
Part of Journal of Translational Medicine, p. 114, 2011
Part of Breast Cancer Research, 2011
Functional and prognostic relevance of the homeobox protein MSX2 in malignant melanoma
Part of British Journal of Cancer, p. 565-574, 2011
Growth differentiation factor 15: a prognostic marker for recurrence in colorectal cancer
Part of British Journal of Cancer, p. 1619-1627, 2011
GAD1 is a biomarker for benign and malignant prostatic tissue
Part of Scandinavian Journal of Urology and Nephrology, p. 39-45, 2011
Part of Journal of Clinical Investigation, p. 784-799, 2011
Part of Journal of Investigative Dermatology, p. 504-508, 2011
RBM3-regulated genes promote DNA integrity and affect clinical outcome in epithelial ovarian cancer
Part of Translational Oncology, p. 212-221, 2011
SATB2 in Combination With Cytokeratin 20 Identifies Over 95% of all Colorectal Carcinomas
Part of American Journal of Surgical Pathology, p. 937-948, 2011
Large-Scale Protein Profiling in Human Cell Lines Using Antibody-Based Proteomics
Part of Journal of Proteome Research, p. 4066-4075, 2011
Diagnostic biomarkers of prostate cancer
Part of Scandinavian Journal of Urology and Nephrology, p. 60-67, 2011
Generation of monospecific antibodies based on affinity capture of polyclonal antibodies
Part of Protein Science, p. 1824-1835, 2011
High nuclear RBM3 expression is associated with an improved prognosis in colorectal cancer
Part of Proteomics Clinical Applications, p. 624-635, 2011
Part of BMC Cancer, p. 125, 2010
Part of Journal of Translational Medicine, p. 78, 2010
Tissue-specific protein expression in human cells. tissues end organs
Part of Journal of Proteomics and Bioinformatics, p. 286-293, 2010
Part of Journal of Histochemistry and Cytochemistry, p. 237-246, 2010
Part of Cancer Genomics & Proteomics, p. 1-7, 2010
Part of International Journal of Cancer, p. 2296-2307, 2010
Towards a knowledge-based Human Protein Atlas
Part of Nature Biotechnology, p. 1248-1250, 2010
International network of cancer genome projects
Part of Nature, p. 993-998, 2010
Toward Next Generation Plasma Profiling via Heat-induced Epitope Retrieval and Array-based Assays
Part of Molecular & Cellular Proteomics, p. 2497-2507, 2010
Part of Pigment Cell and Melanoma Research, p. 542-553, 2010
SOX10 expression in superficial spreading and nodular malignant melanomas
Part of Melanoma research, p. 468-478, 2010
Antibody-based proteomics for discovery and exploration of proteins expressed in pancreatic islets
Part of Discovery Medicine, p. 565-578, 2010
Correlations between RNA and protein expression profiles in 23 human cell lines
Part of BMC Genomics, p. 365, 2009
Part of PLoS biology, 2009
A global view of protein expression in human cells, tissues, and organs
Part of Molecular Systems Biology, p. 337, 2009
Part of Journal of Proteome Research, p. 3689-3692, 2009
Part of Modern Pathology, p. 1564-1574, 2009
Part of British Journal of Cancer, p. 1540-1548, 2009
Selective expression of Syntaxin-7 protein in benign melanocytes and malignant melanoma
Part of Journal of Proteome Research, p. 1639-1646, 2009
Extensive expression of craniofacial related homeobox genes in canine mammary sarcomas
Part of Breast Cancer Research and Treatment, p. 333-343, 2009
The prognostic significance of tryptophanyl-tRNA synthetase in colorectal cancer
Part of Cancer Epidemiology, Biomarkers and Prevention, p. 2949-2956, 2009
Part of Proceedings of the National Academy of Sciences of the United States of America, p. 4396-4401, 2009
Part of American Journal of Pathology, p. 334-341, 2009
Herbal melanin activates TLR4/NF-kappaB signaling pathway
Part of Phytomedicine, p. 477-84, 2009
Part of Epilepsy Research, p. 33-41, 2009
Part of Biophysical Reviews, p. 43-49, 2009
Prognostic impact of tumour-specific HMG-CoA reductase expression in primary breast cancer
Part of Breast Cancer Research, 2008
Part of Melanoma research, p. 412-419, 2008
Part of Nature Genetics, p. 1004-1009, 2008
Part of Journal of proteomics, p. 448-460, 2008
Part of Applied immunohistochemistry & molecular morphology (Print), p. 493-502, 2008
Part of International Journal of Cancer, p. 1146-53, 2008
Part of British Journal of Dermatology, p. 527-38, 2008
Part of Molecular & Cellular Proteomics, p. 825-844, 2008
The protein expression of TRP-1 and galectin-1 in cutaneous malignant melanomas
Part of Cancer Genomics & Proteomics, p. 293-300, 2008
Toward a confocal subcellular atlas of the human proteome
Part of Molecular & Cellular Proteomics, p. 499-508, 2008
The Human Protein Atlas: a tool for pathology
Part of Journal of Pathology, p. 387-93, 2008
Transcriptional profiling of melanocytes from patients with vitiligo vulgaris
Part of Pigment Cell and Melanoma Research, p. 162-171, 2008
A high-throughput strategy for protein profiling in cell microarrays using automated image analysis
Part of Proteomics, p. 2142-2150, 2007
In Situ Identification of Genes Regulated Specifically in Fibroblasts of Human Basal Cell Carcinoma
Part of Journal of Investigative Dermatology, p. 1516-1523, 2007
Part of Molecular Cancer Research, p. 891-897, 2007
The RBCC Gene RFP2 (Leu5) Encodes a Novel Transmembrane E3 Ubiquitin Ligase Involved in ERAD
Part of Molecular Biology of the Cell, p. 1670-1682, 2007
Part of Neuroscience, p. 1689-1703, 2007
Biobanking of fresh frozen tissue: RNA is stable in nonfixed surgical specimens.
Part of Lab Invest, p. 202-11, 2006
Analysis of protein expression in cell microarrays: A tool for antibody-based proteomics
Part of Journal of Histochemistry and Cytochemistry, p. 1413-1423, 2006
Part of Mol Cell Proteomics, p. 1072-81, 2006
Effect of herbal melanin on IL-8: a possible role of Toll-like receptor 4 (TLR4).
Part of Biochem Biophys Res Commun, p. 1200-6, 2006
Part of Proteomics, p. 4327-4337, 2005
A human protein atlas for normal and cancer tissues based on antibody proteomics
Part of Molecular & Cellular Proteomics, p. 1920-1932, 2005
Laser-assisted cell microdissection using the PALM system.
Part of Methods Mol Biol, p. 151-66, 2005
Part of Human Molecular Genetics, p. 3435-3447, 2005
Part of Mutat Res, p. 65-79, 2005
Antibody-based proteomics for human tissue profiling.
Part of Mol Cell Proteomics, p. 384-93, 2005
Part of J Pathol, p. 130-8, 2004
Part of Acta Derm Venereol, p. 439-44, 2004
Antibody-based tissue profiling as a tool for clinical proteomics
Part of Clinical Proteomics, p. 285-299, 2004
Part of Lab Invest, p. 889-99, 2003
Part of Acta Derm Venereol, p. 254, 2003
Similar UV responses are seen in a skin organ culture as in human skin in vivo
Part of Experimental dermatology, p. 349-356, 2002
Rapid increase in diagnosis of cutaneous melanoma in situ in Sweden 1968-1992
Part of Cancer Detect Prev, p. 430-437, 1998
Part of Int J Oncol, p. 111-115, 1997
Elevated levels of the human endogenous retrovirus ERV3 in human sebaceous glands
Part of Journal of Investigative Dermatology, p. 125-128, 1996
Part of Int J Cancer, p. 174-179, 1996
Articles, review/survey
Transcriptomics resources of human tissues and organs
Part of Molecular Systems Biology, 2016
- DOI for Transcriptomics resources of human tissues and organs
- Download full text (pdf) of Transcriptomics resources of human tissues and organs
Part of Molecular Oncology, p. 783-798, 2014
Heart Research Advances Using Database Search Engines, Human Protein Atlas and the Sydney Heart Bank
Part of Heart, Lung and Circulation, p. 819-826, 2013
Part of Proteomics, p. 203-225, 2012
Part of Proteomics, p. 2067-2077, 2012
The Human Protein Atlas as a proteomic resource for biomarker discovery
Part of Journal of Internal Medicine, p. 428-446, 2011
Antibody-based proteomics: fast-tracking molecular diagnostics in oncology
Part of Nature Reviews. Cancer, p. 605-617, 2010
Part of Journal of Internal Medicine, p. 232-245, 2010
Part of Cytometry. Part A : the journal of the International Society for Analytical Cytology, p. 816-832, 2009
Approaching clinical proteomics: current state and future fields of application in fluid proteomics
Part of Clinical Chemistry and Laboratory Medicine, p. 724-744, 2009
A genecentric Human Protein Atlas for expression profiles based on antibodies
Part of Molecular & Cellular Proteomics, p. 2019-2027, 2008
Chapters in book
Antibody Validation for Estrogen Receptor Beta
Part of Estrogen Receptors. Methods in Molecular Biology, p. 1-23, Springer Nature, 2022
Conference papers
Part of ASCO 2018 Gastrointestinal Cancers Symposium, p. 707-707, 2018
2018
Automated Analysis of Human Protein Atlas Immunofluorescence Images
Part of 2009 IEEE International Symposium on Biomedical Imaging, p. 1023-1026, 2009