Fredrik Pontén

Mixed gangliocytoma-pituitary neuroendocrine tumour: clinical, immunohistochemical, and molecular genetic profiles in a series of four patients

Dalakas, Konstantinos; Edén Engström, Britt; Tebani, Abdellah; Bontell, Thomas Olsson et al.

Part of Acta neuropathologica communications, 2026

• DOI for Mixed gangliocytoma-pituitary neuroendocrine tumour: clinical, immunohistochemical, and molecular genetic profiles in a series of four patients
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A human pan-disease blood atlas of the circulating proteome

Álvez, María Bueno; Bergström, Sofia; Kenrick, Josefin; Johansson, Emil et al.

Part of Science, 2025

• DOI for A human pan-disease blood atlas of the circulating proteome

A resource for whole-body gene expression map of human tissues based on integration of single cell and bulk transcriptomics

Shi, Mengnan; Méar, Loren; Karlsson, Max; Alvez, Maria Bueno et al.

Part of Genome Biology, 2025

• DOI for A resource for whole-body gene expression map of human tissues based on integration of single cell and bulk transcriptomics
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CD93 maintains endothelial barrier function and limits metastatic dissemination

Vemuri, Kalyani; de Alves Pereira, Beatriz; Fuenzalida, Patricia; Subashi, Yelin et al.

Part of JCI Insight, 2024

• DOI for CD93 maintains endothelial barrier function and limits metastatic dissemination
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Prognostic genome and transcriptome signatures in colorectal cancers

Nunes, Luís; Li, Fuqiang; Wu, Meizhen; Luo, Tian et al.

Part of Nature, p. 137-146, 2024

• DOI for Prognostic genome and transcriptome signatures in colorectal cancers
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Mixed gangliocytoma-pituitary neuroendocrine tumour: clinical, immunohistochemical, and molecular genetic profiles in a series of four patients

Dalakas, Konstantinos; Edén Engström, Britt; Tebani, Abdellah; Bontell, Thomas Olsson et al.

Part of Acta neuropathologica communications, 2026

• DOI for Mixed gangliocytoma-pituitary neuroendocrine tumour: clinical, immunohistochemical, and molecular genetic profiles in a series of four patients
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A human pan-disease blood atlas of the circulating proteome

Álvez, María Bueno; Bergström, Sofia; Kenrick, Josefin; Johansson, Emil et al.

Part of Science, 2025

• DOI for A human pan-disease blood atlas of the circulating proteome

A resource for whole-body gene expression map of human tissues based on integration of single cell and bulk transcriptomics

Shi, Mengnan; Méar, Loren; Karlsson, Max; Alvez, Maria Bueno et al.

Part of Genome Biology, 2025

• DOI for A resource for whole-body gene expression map of human tissues based on integration of single cell and bulk transcriptomics
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CD93 maintains endothelial barrier function and limits metastatic dissemination

Vemuri, Kalyani; de Alves Pereira, Beatriz; Fuenzalida, Patricia; Subashi, Yelin et al.

Part of JCI Insight, 2024

• DOI for CD93 maintains endothelial barrier function and limits metastatic dissemination
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Prognostic genome and transcriptome signatures in colorectal cancers

Nunes, Luís; Li, Fuqiang; Wu, Meizhen; Luo, Tian et al.

Part of Nature, p. 137-146, 2024

• DOI for Prognostic genome and transcriptome signatures in colorectal cancers
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Transcriptome Analysis Reveals Distinct Patterns Between the Invasive and Noninvasive Pituitary Neuroendocrine Tumors

Jotanovic, Jelena; Tebani, Abdellah; Hekmati, Neda; Sivertsson, Åsa et al.

Part of Journal of the Endocrine Society, 2024

• DOI for Transcriptome Analysis Reveals Distinct Patterns Between the Invasive and Noninvasive Pituitary Neuroendocrine Tumors
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The impact of sex on treatment and outcome in relation to histological subtype in patients with resectable gastric cancer: Results from the randomized CRITICS trial

Caspers, Irene A.; Slagter, Astrid E.; Lind, Pehr; Sikorska, Karolina et al.

Part of Journal of Surgical Oncology, p. 734-744, 2024

• DOI for The impact of sex on treatment and outcome in relation to histological subtype in patients with resectable gastric cancer: Results from the randomized CRITICS trial

A human stomach cell type transcriptome atlas

Öling, S.; Struck, E.; Noreen-Thorsen, M.; Zwahlen, M. et al.

Part of BMC Biology, 2024

• DOI for A human stomach cell type transcriptome atlas
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Effect of preoperative chemotherapy on the histopathological classification of gastric cancer

Caspers, I. A.; Biesma, H. D.; Wiklund, K.; Pontén, Fredrik et al.

Part of Gastric Cancer, p. 102-109, 2024

• DOI for Effect of preoperative chemotherapy on the histopathological classification of gastric cancer
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An immune score reflecting pro- and anti-tumoural balance of tumour microenvironment has major prognostic impact and predicts immunotherapy response in solid cancers

Mezheyeuski, Artur; Backman, Max; Mattsson, Johanna Sofia Margareta; Martin-Bernabe, Alfonso et al.

Part of eBioMedicine, 2023

• DOI for An immune score reflecting pro- and anti-tumoural balance of tumour microenvironment has major prognostic impact and predicts immunotherapy response in solid cancers
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Next generation pan-cancer blood proteome profiling using proximity extension assay

Alvez, Maria Bueno; Edfors, Fredrik; von Feilitzen, Kalle; Zwahlen, Martin et al.

Part of Nature Communications, 2023

• DOI for Next generation pan-cancer blood proteome profiling using proximity extension assay
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Imaging of fibrogenesis in the liver by [¹⁸F]TZ-Z09591, an Affibody molecule targeting platelet derived growth factor receptor β

Wegrzyniak, Olivia; Zhang, Bo; Rokka, Johanna; Rosestedt, Maria et al.

Part of EJNMMI Radiopharmacy and Chemistry, 2023

• DOI for Imaging of fibrogenesis in the liver by [¹⁸F]TZ-Z09591, an Affibody molecule targeting platelet derived growth factor receptor β
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Spatial immunophenotyping of the tumour microenvironment in non-small cell lung cancer

Backman, Max; Strell, Carina; Lindberg, Amanda; Mattsson, Johanna S. M. et al.

Part of European Journal of Cancer, p. 40-52, 2023

• DOI for Spatial immunophenotyping of the tumour microenvironment in non-small cell lung cancer
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Absolute Quantification of Pan-Cancer Plasma Proteomes Reveals Unique Signature in Multiple Myeloma

Kotol, David; Woessmann, Jakob; Hober, Andreas; Alvez, Maria Bueno et al.

Part of Cancers, 2023

• DOI for Absolute Quantification of Pan-Cancer Plasma Proteomes Reveals Unique Signature in Multiple Myeloma
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A human adipose tissue cell-type transcriptome atlas

Norreen-Thorsen, Marthe; Struck, Eike Christopher; Oling, Sofia; Zwahlen, Martin et al.

Part of Cell Reports, 2022

• DOI for A human adipose tissue cell-type transcriptome atlas
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Combined expression of HOXA11 and CD10 identifies endometriosis versus normal tissue and tumors

Bergman-Larsson, Julia; Gustafsson, Sofie; Méar, Loren; Huvila, Jutta et al.

Part of Annals of Diagnostic Pathology, 2022

• DOI for Combined expression of HOXA11 and CD10 identifies endometriosis versus normal tissue and tumors
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Genome-wide annotation of protein-coding genes in pig

Karlsson, Max; Sjöstedt, Evelina; Oksvold, Per; Sivertsson, Asa et al.

Part of BMC Biology, 2022

• DOI for Genome-wide annotation of protein-coding genes in pig
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Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level

Wang, Fei; Ding, Peiwen; Liang, Xue; Ding, Xiangning et al.

Part of Nature Communications, 2022

• DOI for Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level
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Infiltration of NK and plasma cells is associated with a distinct immune subset in non‐small cell lung cancer

Backman, Max; La Fleur, Linnea; Kurppa, Pinja; Djureinovic, Dijana et al.

Part of Journal of Pathology, p. 243-256, 2021

• DOI for Infiltration of NK and plasma cells is associated with a distinct immune subset in non‐small cell lung cancer
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The prognostic impact of the tumour stroma fraction: A machine learning-based analysis in 16 human solid tumour types

Micke, Patrick; Strell, Carina; Mattsson, Johanna Sofia Margareta; Martin-Bernabe, Alfonso et al.

Part of eBioMedicine, 2021

• DOI for The prognostic impact of the tumour stroma fraction: A machine learning-based analysis in 16 human solid tumour types
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ELTD1-deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma.

Huang, Hua; Georganaki, Maria; Conze, Lei Liu; Laviña, Bàrbara et al.

Part of Neuro-Oncology, p. 398-411, 2021

• DOI for ELTD1-deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma.
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A single-cell type transcriptomics map of human tissues

Karlsson, Max; Zhang, Cheng; Méar, Loren; Zhong, Wen et al.

Part of Science Advances, 2021

• DOI for A single-cell type transcriptomics map of human tissues
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Spatiotemporal dissection of the cell cycle with single-cell proteogenomics

Mahdessian, Diana; Cesnik, Anthony J.; Gnann, Christian; Danielsson, Frida et al.

Part of Nature, p. 649-654, 2021

• DOI for Spatiotemporal dissection of the cell cycle with single-cell proteogenomics

The Immune Landscape of Colorectal Cancer

Mezheyeuski, Artur; Micke, Patrick; Martin-Bernabe, Alfonso; Backman, Max et al.

Part of Cancers, 2021

• DOI for The Immune Landscape of Colorectal Cancer
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The noncoding MIR100HG RNA enhances the autocrine function of transforming growth factor beta signaling

Papoutsoglou, Panagiotis; Rodrigues Junior, Dorival Mendes; Morén, Anita; Bergman, Andrew et al.

Part of Oncogene, p. 3748-3765, 2021

• DOI for The noncoding MIR100HG RNA enhances the autocrine function of transforming growth factor beta signaling
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Annotation of pituitary neuroendocrine tumors with genome-wide expression analysis

Tebani, Abdellah; Jotanovic, Jelena; Hekmati, Neda; Sivertsson, Åsa et al.

Part of Acta neuropathologica communications, 2021

• DOI for Annotation of pituitary neuroendocrine tumors with genome-wide expression analysis

Molecular characterization of a large unselected cohort of metastatic colorectal cancers in relation to primary tumor location, rare metastatic sites and prognosis

Nunes, Luís; Aasebø, Kristine; Mathot, Lucy; Ljungström, Viktor et al.

Part of Acta Oncologica, p. 417-426, 2020

• DOI for Molecular characterization of a large unselected cohort of metastatic colorectal cancers in relation to primary tumor location, rare metastatic sites and prognosis
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An atlas of the protein-coding genes in the human, pig, and mouse brain

Sjostedt, Evelina; Zhong, Wen; Fagerberg, Linn; Karlsson, Max et al.

Part of Science, p. 1090-+, 2020

• DOI for An atlas of the protein-coding genes in the human, pig, and mouse brain

CDX2: A Prognostic Marker in Metastatic Colorectal Cancer Defining a Better BRAF Mutated and a Worse KRAS Mutated Subgroup

Aasebo, Kristine; Dragomir, Anca; Sundström, Magnus; Mezheyeuski, Artur et al.

Part of Frontiers in Oncology, 2020

• DOI for CDX2: A Prognostic Marker in Metastatic Colorectal Cancer Defining a Better BRAF Mutated and a Worse KRAS Mutated Subgroup
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Metastatic colorectal carcinomas with high SATB2 expression are associated with better prognosis and response to chemotherapy: a population-based Scandinavian study

Mezheyeuski, Artur; Pontén, Fredrik; Edqvist, Per-Henrik D; Sundström, Magnus et al.

Part of Acta Oncologica, p. 284-290, 2020

• DOI for Metastatic colorectal carcinomas with high SATB2 expression are associated with better prognosis and response to chemotherapy: a population-based Scandinavian study
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Proximity Ligation Assay as a Tool for Antibody Validation in Human Tissues

Lindskog, Cecilia; Backman, Max; Zieba, Agata; Asplund, Anna et al.

Part of Journal of Histochemistry and Cytochemistry, p. 515-529, 2020

• DOI for Proximity Ligation Assay as a Tool for Antibody Validation in Human Tissues

Blood-derived biomarkers correlate with clinical progression in Duchenne muscular dystrophy

Strandberg, Kristin; Ayoglu, Burcu; Roos, Andreas; Reza, Mojgan et al.

Part of JOURNAL OF NEUROMUSCULAR DISEASES, p. 231-246, 2020

• DOI for Blood-derived biomarkers correlate with clinical progression in Duchenne muscular dystrophy
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Quantification and discovery of sequence determinants of protein-per-mRNA amount in 29 human tissues

Eraslan, Basak; Wang, Dongxue; Gusic, Mirjana; Prokisch, Holger et al.

Part of Molecular Systems Biology, 2019

• DOI for Quantification and discovery of sequence determinants of protein-per-mRNA amount in 29 human tissues
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The human secretome

Uhlen, Mathias; Karlsson, Max J.; Hober, Andreas; Svensson, Anne-Sophie et al.

Part of Science Signaling, 2019

• DOI for The human secretome

A deep proteome and transcriptome abundance atlas of 29 healthy human tissues

Wang, Dongxue; Eraslan, Basak; Wieland, Thomas; Hallstrom, Bjorn et al.

Part of Molecular Systems Biology, 2019

• DOI for A deep proteome and transcriptome abundance atlas of 29 healthy human tissues
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Consequences of a high incidence of microsatellite instability and BRAF-mutated tumors: A population-based cohort of metastatic colorectal cancer patients

Aasebö, Kristine Ö.; Dragomir, Anca; Sundström, Magnus; Mezheyeuski, Artur et al.

Part of Cancer Medicine, p. 3623-3635, 2019

• DOI for Consequences of a high incidence of microsatellite instability and BRAF-mutated tumors: A population-based cohort of metastatic colorectal cancer patients
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Tumoral pyruvate kinase L/R as a predictive marker for the treatment of renal cancer patients with sunitinib and sorafenib

Niinivirta, Marjut; Enblad, Gunilla; Lindskog, Cecilia; Pontén, Fredrik et al.

Part of Journal of Cancer, p. 3224-3231, 2019

• DOI for Tumoral pyruvate kinase L/R as a predictive marker for the treatment of renal cancer patients with sunitinib and sorafenib
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Systematic assessment of antibody selectivity in plasma based on a resource of enrichment profiles

Fredolini, Claudia; Byström, Sanna; Sanchez-Rivera, Laura; Ioannou, Marina et al.

Part of Scientific Reports, 2019

• DOI for Systematic assessment of antibody selectivity in plasma based on a resource of enrichment profiles
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A genome-wide transcriptomic analysis of protein-coding genes in human blood cells

Uhlen, Mathias; Karlsson, Max J.; Zhong, Wen; Tebani, Abdellah et al.

Part of Science, p. 1471-+, 2019

• DOI for A genome-wide transcriptomic analysis of protein-coding genes in human blood cells

LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer

Cadenas, Cristina; Vosbeck, Sonja; Edlund, Karolina; Grgas, Katharina et al.

Part of International Journal of Cancer, p. 901-915, 2019

• DOI for LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer
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Prognostic Impact of Tumor Cell Programmed Death Ligand 1 Expression and Immune Cell Infiltration in NSCLC

Edlund, Karolina; Madjar, Katrin; Mattsson, Johanna Sofia Margareta; Djureinovic, Dijana et al.

Part of Journal of Thoracic Oncology, p. 628-640, 2019

• DOI for Prognostic Impact of Tumor Cell Programmed Death Ligand 1 Expression and Immune Cell Infiltration in NSCLC
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Stroma-normalised vessel density predicts benefit from adjuvant fluorouracil-based chemotherapy in patients with stage II/III colon cancer

Mezheyeuski, Artur; Hrynchyk, Ina; Herrera, Mercedes; Karlberg, Mia et al.

Part of British Journal of Cancer, p. 303-311, 2019

• DOI for Stroma-normalised vessel density predicts benefit from adjuvant fluorouracil-based chemotherapy in patients with stage II/III colon cancer

Novel Multiomics Profiling of Human Carotid Atherosclerotic Plaques and Plasma Reveals Biliverdin Reductase B as a Marker of Intraplaque Hemorrhage

Matic, Ljubica Perisic; Iglesias, Maria Jesus; Vesterlund, Mattias; Lengquist, Mariette et al.

Part of JACC: Basic to Translational Science, p. 464-480, 2018

• DOI for Novel Multiomics Profiling of Human Carotid Atherosclerotic Plaques and Plasma Reveals Biliverdin Reductase B as a Marker of Intraplaque Hemorrhage
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Mining the Human Tissue Proteome for Protein Citrullination

Lee, Chien-Yun; Wang, Dongxue; Wilhelm, Mathias; Zolg, Daniel P. et al.

Part of Molecular & Cellular Proteomics, p. 1378-1391, 2018

• DOI for Mining the Human Tissue Proteome for Protein Citrullination

U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.

Glimelius, Bengt; Melin, Beatrice; Enblad, Gunilla; Alafuzoff, Irina et al.

Part of Acta Oncologica, p. 187-194, 2018

• DOI for U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden.
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Combined ASRGL1 and p53 immunohistochemistry as an independent predictor of survival in endometrioid endometrial carcinoma

Huvila, Jutta; Laajala, Teemu D.; Edqvist, Per-Henrik D; Mardinoglu, Adil et al.

Part of Gynecologic Oncology, p. 173-180, 2018

• DOI for Combined ASRGL1 and p53 immunohistochemistry as an independent predictor of survival in endometrioid endometrial carcinoma

Immunohistochemistry for transcription factor T-Pit as a tool in diagnostics of corticotroph pituitary tumours

Casar Borota, Olivera; Bollerslev, Jens; Pontén, Fredrik

Part of Pituitary, p. 443-443, 2018

• DOI for Immunohistochemistry for transcription factor T-Pit as a tool in diagnostics of corticotroph pituitary tumours

Detection of autoantibodies against cancer-testis antigens in non-small cell lung cancer

Djureinovic, Dijana; Dodig-Crnkovic, Tea; Hellström, Cecilia; Holgersson, Georg et al.

Part of Lung Cancer, p. 157-163, 2018

• DOI for Detection of autoantibodies against cancer-testis antigens in non-small cell lung cancer

In situ protein detection with enhanced specificity using DNA-conjugated antibodies and proximity ligation

Zieba, Agata; Ponten, Fredrik; Uhlen, Mathias; Landegren, Ulf

Part of Modern Pathology, p. 253-263, 2018

• DOI for In situ protein detection with enhanced specificity using DNA-conjugated antibodies and proximity ligation

Reaching the limits of prognostication in non-small cell lung cancer: an optimized biomarker panel fails to outperform clinical parameters.

Grinberg, Marianna; Djureinovic, Dijana; Brunnström, Hans R R; Mattsson, Johanna Sofia Margareta et al.

Part of Modern Pathology, p. 964-977, 2017

• DOI for Reaching the limits of prognostication in non-small cell lung cancer: an optimized biomarker panel fails to outperform clinical parameters.

A systematic search strategy identifies cubilin as independent prognostic marker for renal cell carcinoma

Gremel, Gabriela; Djureinovic, Dijana; Niinivirta, Marjut; Laird, Alexander et al.

Part of BMC Cancer, 2017

• DOI for A systematic search strategy identifies cubilin as independent prognostic marker for renal cell carcinoma
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Mast Cell Infiltration in Human Brain Metastases Modulates the Microenvironment and Contributes to the Metastatic Potential

Roy, Ananya; Libard, Sylwia; Weishaupt, Holger; Gustavsson, Ida et al.

Part of Frontiers in Oncology, 2017

• DOI for Mast Cell Infiltration in Human Brain Metastases Modulates the Microenvironment and Contributes to the Metastatic Potential
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Serglycin as a potential biomarker for glioma: association of serglycin expression, extent of mast cell recruitment and glioblastoma progression

Roy, Ananya; Attarha, Sanaz; Weishaupt, Holger; Edqvist, Per-Henrik et al.

Part of Oncotarget, p. 24815-24827, 2017

• DOI for Serglycin as a potential biomarker for glioma: association of serglycin expression, extent of mast cell recruitment and glioblastoma progression
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Tumoral ANXA1 Is a Predictive Marker for Sunitinib Treatment of Renal Cancer Patients

Niinivirta, Marjut; Enblad, Gunilla; Edqvist, Per-Henrik D; Pontén, Fredrik et al.

Part of Journal of Cancer, p. 3975-3983, 2017

• DOI for Tumoral ANXA1 Is a Predictive Marker for Sunitinib Treatment of Renal Cancer Patients
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A specific antibody to detect transcription factor T-Pit: a reliable marker of corticotroph cell differentiation and a tool to improve the classification of pituitary neuroendocrine tumours

Sjöstedt, Evelina; Bollerslev, Jens; Mulder, Jan; Lindskog, Cecilia et al.

Part of Acta Neuropathologica, p. 675-677, 2017

• DOI for A specific antibody to detect transcription factor T-Pit: a reliable marker of corticotroph cell differentiation and a tool to improve the classification of pituitary neuroendocrine tumours

A subcellular map of the human proteome

Thul, Peter J.; åkesson, Lovisa; Wiking, Mikaela; Mahdessian, Diana et al.

Part of Science, 2017

• DOI for A subcellular map of the human proteome

High RBM3 expression is associated with an improved survival and oxaliplatin response in patients with metastatic colorectal cancer

Siesing, Christina; Sorbye, Halfdan; Dragomir, Anca; Pfeiffer, Per et al.

Part of PLOS ONE, 2017

• DOI for High RBM3 expression is associated with an improved survival and oxaliplatin response in patients with metastatic colorectal cancer
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Tumoral cubilin is a predictive marker for treatment of renal cancer patients with sunitinib and sorafenib

Niinivirta, Marjut; Enblad, Gunilla; Edqvist, Per-Henrik; Pontén, Fredrik et al.

Part of Journal of Cancer Research and Clinical Oncology, p. 961-970, 2017

• DOI for Tumoral cubilin is a predictive marker for treatment of renal cancer patients with sunitinib and sorafenib
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A pathology atlas of the human cancer transcriptome

Uhlen, Mathias; Zhang, Cheng; Lee, Sunjae; Sjöstedt, Evelina et al.

Part of Science, 2017

• DOI for A pathology atlas of the human cancer transcriptome

The human adrenal gland proteome defined by transcriptomics and antibody-based profiling

Bergman, Julia; Botling, Johan; Fagerberg, Linn; Hallström, Björn M. et al.

Part of Endocrinology, p. 239-251, 2017

• DOI for The human adrenal gland proteome defined by transcriptomics and antibody-based profiling

Serotonin, ATRX, and DAXX Expression in Pituitary Adenomas: Markers in the Differential Diagnosis of Neuroendocrine Tumors of the Sellar Region.

Casar Borota, Olivera; Botling, Johan; Granberg, Dan; Stigare, Jerker et al.

Part of American Journal of Surgical Pathology, p. 1238-1246, 2017

• DOI for Serotonin, ATRX, and DAXX Expression in Pituitary Adenomas: Markers in the Differential Diagnosis of Neuroendocrine Tumors of the Sellar Region.

A nonsense mutation in CEP55 defines a new locus for a Meckel-like syndrome, an autosomal recessive lethal fetal ciliopathy.

Bondeson, Marie-Louise; Ericson, Katharina; Gudmundsson, Sanna; Ameur, Adam et al.

Part of Clinical Genetics, p. 510-516, 2017

• DOI for A nonsense mutation in CEP55 defines a new locus for a Meckel-like syndrome, an autosomal recessive lethal fetal ciliopathy.

Principles of Systems Biology, No. 21: Editorial

Cao, Junyue; Packer, Jonathan; Waterston, Robert; Trapnell, Cole et al.

Part of CELL SYSTEMS, p. 158-160, 2017

• DOI for Principles of Systems Biology, No. 21: Editorial

Cetuximab sensitivity of head and neck squamous cell carcinoma xenografts is associated with treatment-induced reduction in EGFR, pEGFR, and pSrc.

Jedlinski, Adam; Garvin, Stina; Johansson, Ann-Charlotte; Edqvist, Per-Henrik D et al.

Part of Journal of Oral Pathology & Medicine, p. 717-724, 2017

• DOI for Cetuximab sensitivity of head and neck squamous cell carcinoma xenografts is associated with treatment-induced reduction in EGFR, pEGFR, and pSrc.

Breast cancer in young women and prognosis: How important are proliferation markers?

Fredholm, Hanna; Magnusson, Kristina; Lindstrom, Linda S.; Tobin, Nicholas P. et al.

Part of European Journal of Cancer, p. 278-289, 2017

• DOI for Breast cancer in young women and prognosis: How important are proliferation markers?

Affinity Proteomics Exploration of Melanoma Identifies Proteins in Serum with Associations to T-Stage and Recurrence

Byström, Sanna; Fredolini, Claudia; Edqvist, Per-Henrik D; Nyaiesh, Etienne-Nicholas et al.

Part of Translational Oncology, p. 385-395, 2017

• DOI for Affinity Proteomics Exploration of Melanoma Identifies Proteins in Serum with Associations to T-Stage and Recurrence

A stromal cell population in the large intestine identified by tissue factor expression that is lost during colorectal cancer progression

Eriksson, Oskar; Asplund, Anna; Hegde, Geeta; Edqvist, Per-Henrik D et al.

Part of Thrombosis and Haemostasis, p. 1050-1059, 2016

• DOI for A stromal cell population in the large intestine identified by tissue factor expression that is lost during colorectal cancer progression

Inconsistent results in the analysis of ALK rearrangements in non-small cell lung cancer

Mattsson, Johanna Sofia Margareta; Brunnström, Hans; Jabs, Verena; Edlund, Karolina et al.

Part of BMC Cancer, 2016

• DOI for Inconsistent results in the analysis of ALK rearrangements in non-small cell lung cancer
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ANLN is a prognostic biomarker independent of Ki-67 and essential for cell cycle progression in primary breast cancer

Magnusson, Kristina; Gremel, Gabriela; Rydén, Lisa; Pontén, Victor et al.

Part of BMC Cancer, 2016

• DOI for ANLN is a prognostic biomarker independent of Ki-67 and essential for cell cycle progression in primary breast cancer
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PROX1 is a novel pathway-specific prognostic biomarker for high-grade astrocytomas; results from independent glioblastoma cohorts stratified by age and IDH mutation status.

Roodakker, Kenney R.; Elsir, Tamador; Edqvist, Per-Henrik D; Hägerstrand, Daniel et al.

Part of Oncotarget, p. 72431-72442, 2016

• DOI for PROX1 is a novel pathway-specific prognostic biomarker for high-grade astrocytomas; results from independent glioblastoma cohorts stratified by age and IDH mutation status.
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Survival-associated heterogeneity of marker-defined perivascular cells in colorectal cancer

Mezheyeuski, Artur; Lindh, Maja Bradic; Guren, Tormod Kyrre; Dragomir, Anca et al.

Part of Oncotarget, p. 41948-41958, 2016

• DOI for Survival-associated heterogeneity of marker-defined perivascular cells in colorectal cancer

GPR44 is a pancreatic protein restricted to the human beta cell

Hellström-Lindahl, Ewa; Danielsson, Angelika; Pontén, Fredrik; Czernichow, Paul et al.

Part of Acta Diabetologica, p. 413-421, 2016

• DOI for GPR44 is a pancreatic protein restricted to the human beta cell

SATB2 is expressed in Merkel cell carcinoma

Fukuhara, Mari; Agnarsdottir, Margret; Edqvist, Per-Henrik; Coter, Anna et al.

Part of Archives of Dermatological Research, p. 449-454, 2016

• DOI for SATB2 is expressed in Merkel cell carcinoma

Long-term outcome in young women with breast cancer: a population-based study

Fredholm, Hanna; Magnusson, Kristina; Lindström, Linda S.; Garmo, Hans et al.

Part of Breast Cancer Research and Treatment, p. 131-143, 2016

• DOI for Long-term outcome in young women with breast cancer: a population-based study
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Guidance Molecule SEMA3A Restricts Tumor Growth by Differentially Regulating the Proliferation of Tumor-Associated Macrophages

Wallerius, Majken; Wallmann, Tatjana; Bartish, Margarita; Ostling, Jeanette et al.

Part of Cancer Research, p. 3166-3178, 2016

• DOI for Guidance Molecule SEMA3A Restricts Tumor Growth by Differentially Regulating the Proliferation of Tumor-Associated Macrophages

Profiling cancer testis antigens in non-small-cell lung cancer

Djureinovic, Dijana; Hallström, Bjorn M.; Horie, Masafumi; Mattsson, Johanna Sofia Margareta et al.

Part of JCI INSIGHT, 2016

• DOI for Profiling cancer testis antigens in non-small-cell lung cancer

Extension of diffuse low-grade gliomas beyond radiological borders as shown by the coregistration of histopathological and magnetic resonance imaging data

Zetterling, Maria; Roodakker, Kenney Roy; Berntsson, Shala Ghaderi; Edqvist, Per-Henrik D et al.

Part of Journal of Neurosurgery, p. 1155-1166, 2016

• DOI for Extension of diffuse low-grade gliomas beyond radiological borders as shown by the coregistration of histopathological and magnetic resonance imaging data

System-wide Clinical Proteomics of Breast Cancer Reveals Global Remodeling of Tissue Homeostasis

Pozniak, Yair; Balint-Lahat, Nora; Rudolph, Jan Daniel; Lindskog, Cecilia et al.

Part of CELL SYSTEMS, p. 172-184, 2016

• DOI for System-wide Clinical Proteomics of Breast Cancer Reveals Global Remodeling of Tissue Homeostasis

Analysis of Body-wide Unfractionated Tissue Data to Identify a Core Human Endothelial Transcriptome.

Butler, Lynn Marie; Hallström, Björn Mikael; Fagerberg, Linn; Pontén, Fredrik C et al.

Part of Cell systems, p. 287-301000, 2016

• DOI for Analysis of Body-wide Unfractionated Tissue Data to Identify a Core Human Endothelial Transcriptome.

The protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene

van Kempen, Leon C. L.; Redpath, Margaret; Elchebly, Mounib; Klein, Kathleen Oros et al.

Part of Science Translational Medicine, 2016

• DOI for The protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene

Oncogene-Induced Senescence in Pituitary Adenomas-an Immunohistochemical Study.

Manojlovic-Gacic, Emilija; Skender-Gazibara, Milica; Popovic, Vera; Soldatovic, Ivan et al.

Part of Endocrine pathology, p. 1-11, 2016

• DOI for Oncogene-Induced Senescence in Pituitary Adenomas-an Immunohistochemical Study.

Visualization and analysis of gene expression in tissue sections by spatial transcriptomics

Stahl, Patrik L.; Salmen, Fredrik; Vickovic, Sanja; Lundmark, Anna et al.

Part of Science, p. 78-82, 2016

• DOI for Visualization and analysis of gene expression in tissue sections by spatial transcriptomics

Gene-specific correlation of RNA and protein levels in human cells and tissues

Edfors, Fredrik; Danielsson, Frida; Hallström, Björn M.; Käll, Lukas et al.

Part of Molecular Systems Biology, 2016

• DOI for Gene-specific correlation of RNA and protein levels in human cells and tissues
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Elevated Expression of the C-Type Lectin CD93 in the Glioblastoma Vasculature Regulates Cytoskeletal Rearrangements That Enhance Vessel Function and Reduce Host Survival

Langenkamp, Elise; Zhang, Lei; Lugano, Roberta; Huang, Hua et al.

Part of Cancer Research, p. 4504-4516, 2015

• DOI for Elevated Expression of the C-Type Lectin CD93 in the Glioblastoma Vasculature Regulates Cytoskeletal Rearrangements That Enhance Vessel Function and Reduce Host Survival

Complementing tissue characterization by integrating transcriptome profiling from the Human Protein Atlas and from the FANTOM5 consortium

Yu, Nancy Yiu-Lin; Hallstrom, Bjorn M.; Fagerberg, Linn; Pontén, Fredrik et al.

Part of Nucleic Acids Research, p. 6787-6798, 2015

• DOI for Complementing tissue characterization by integrating transcriptome profiling from the Human Protein Atlas and from the FANTOM5 consortium
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A Tissue-Based Map of the Human Proteome

Pontén, Fredrik

Part of Scandinavian Journal of Immunology, p. 329-329, 2015

The Urinary Bladder Transcriptome and Proteome Defined by Transcriptomics and Antibody-Based Profiling

Habuka, Masato; Fagerberg, Linn; Hallström, Björn M.; Pontén, Fredrik et al.

Part of PLOS ONE, 2015

• DOI for The Urinary Bladder Transcriptome and Proteome Defined by Transcriptomics and Antibody-Based Profiling
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Defining the Human Brain Proteome Using Transcriptomics and Antibody-Based Profiling with a Focus on the Cerebral Cortex

Sjöstedt, Evelina; Fagerberg, Linn; Hallstrom, Bjorn M.; Haggmark, Anna et al.

Part of PLOS ONE, 2015

• DOI for Defining the Human Brain Proteome Using Transcriptomics and Antibody-Based Profiling with a Focus on the Cerebral Cortex
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Loss of ASRGL1 expression is an independent biomarker for disease-specific survival in endometrioid endometrial carcinoma

Edqvist, Per-Henrik D.; Huvila, Jutta; Forsstrom, Bjorn; Talve, Lauri et al.

Part of Gynecologic Oncology, p. 529-537, 2015

• DOI for Loss of ASRGL1 expression is an independent biomarker for disease-specific survival in endometrioid endometrial carcinoma

Expression of Human Skin-Specific Genes Defined by Transcriptomics and Antibody-Based Profiling

Edqvist, Per-Henrik D; Fagerberg, Linn; Hallström, Björn M; Danielsson, Angelika et al.

Part of Journal of Histochemistry and Cytochemistry, p. 129-141, 2015

• DOI for Expression of Human Skin-Specific Genes Defined by Transcriptomics and Antibody-Based Profiling

The Human Endometrium-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling

Zieba, Agata; Sjöstedt, Evelina; Olovsson, Matts; Fagerberg, Linn et al.

Part of Omics, p. 659-668, 2015

• DOI for The Human Endometrium-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling

Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR

Vizoso, Miguel; Ferreira, Humberto J.; Lopez-Serra, Paula; Javier Carmona, F. et al.

Part of Nature Medicine, p. 741-+, 2015

• DOI for Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR

The human cardiac and skeletal muscle proteomes defined by transcriptomics and antibody-based profiling

Lindskog, Cecilia; Linné, Jerker; Fagerberg, Linn; Hallstrom, Bjorn M. et al.

Part of BMC Genomics, 2015

• DOI for The human cardiac and skeletal muscle proteomes defined by transcriptomics and antibody-based profiling
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Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells

Roy, Ananya; Coum, Antoine; Marinescu, Voichita D; Põlajeva, Jelena et al.

Part of Oncotarget, p. 23647-23661, 2015

• DOI for Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells
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The Identification of Therapeutic Targets in Lung Cancer Based on Transcriptomic and Proteomic Characterization of Cancer-Testis Antigens

Djureinovic, Dijana; Hallström, Björn; Mattsson, Johanna Sofia Margareta; La Fleur, Linnea et al.

Part of Journal of Thoracic Oncology, 2015

Pleiotrophin promotes vascular abnormalization in gliomas and correlates with poor survival in patients with astrocytomas.

Zhang, Lei; Kundu, Soumi; Feenstra, Tjerk; Li, Xiujuan et al.

Part of Science Signaling, 2015

• DOI for Pleiotrophin promotes vascular abnormalization in gliomas and correlates with poor survival in patients with astrocytomas.

Tumor Vessel Up-Regulation of INSR Revealed by Single-Cell Expression Analysis of the Tyrosine Kinome and Phosphatome in Human Cancers

Kiflemariam, Sara; Ljungström, Viktor; Pontén, Fredrik; Sjöblom, Tobias

Part of American Journal of Pathology, p. 1600-1609, 2015

• DOI for Tumor Vessel Up-Regulation of INSR Revealed by Single-Cell Expression Analysis of the Tyrosine Kinome and Phosphatome in Human Cancers

The human gastrointestinal tract-specific transcriptome and proteome as defined by RNA sequencing and antibody-based profiling.

Gremel, Gabriela; Wanders, Alkwin; Cedernaes, Jonathan; Fagerberg, Linn et al.

Part of Journal of gastroenterology, p. 46-57, 2015

• DOI for The human gastrointestinal tract-specific transcriptome and proteome as defined by RNA sequencing and antibody-based profiling.

A prognosis based classification of undifferentiated uterine sarcomas: Identification of mitotic index, hormone receptors and YWHAE-FAM22 translocation status as predictors of survival

Gremel, Gabriela; Liew, Markus; Hamzei, Farzaneh; Hardell, Elin et al.

Part of International Journal of Cancer, p. 1608-1618, 2015

• DOI for A prognosis based classification of undifferentiated uterine sarcomas: Identification of mitotic index, hormone receptors and YWHAE-FAM22 translocation status as predictors of survival

Analysis of the Human Prostate-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling Identifies TMEM79 and ACOXL as Two Putative, Diagnostic Markers in Prostate Cancer

O'Hurley, Gillian; Busch, Christer; Fagerberg, Linn; Hallstrom, Bjorn M. et al.

Part of PLOS ONE, 2015

• DOI for Analysis of the Human Prostate-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling Identifies TMEM79 and ACOXL as Two Putative, Diagnostic Markers in Prostate Cancer
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High BRAF Mutation Frequency and Marked Survival Differences in Subgroups According to KRAS/BRAF Mutation Status and Tumor Tissue Availability in a Prospective Population-Based Metastatic Colorectal Cancer Cohort

Sorbye, Halfdan; Dragomir, Anca; Sundström, Magnus; Pfeiffer, Per et al.

Part of PLOS ONE, 2015

• DOI for High BRAF Mutation Frequency and Marked Survival Differences in Subgroups According to KRAS/BRAF Mutation Status and Tumor Tissue Availability in a Prospective Population-Based Metastatic Colorectal Cancer Cohort

High levels of WNT-5A in human glioma correlate with increased presence of tumor-associated microglia/monocytes

Dijksterhuis, Jacomijn P.; Arthofer, Elisa; Marinescu, Voichita D.; Nelander, Sven et al.

Part of Experimental Cell Research, p. 280-288, 2015

• DOI for High levels of WNT-5A in human glioma correlate with increased presence of tumor-associated microglia/monocytes

Prognostic impact of COX-2 in non-small cell lung cancer: A comprehensive compartment-specific evaluation of tumor and stromal cell expression

Mattsson, Johanna Sofia Margareta; Bergman, Bengt; Grinberg, Marianna; Edlund, Karolina et al.

Part of Cancer Letters, p. 837-845, 2015

• DOI for Prognostic impact of COX-2 in non-small cell lung cancer: A comprehensive compartment-specific evaluation of tumor and stromal cell expression

ALK Rearrangements in Non-Small Cell Lung Cancer: Comprehensive Integration of Genomic, Gene Expression and Protein Analysis

Mattsson, Johanna S. M.; Svensson, Maria A.; Hallström, Björn; Koyi, Hirsh et al.

Part of Journal of Thoracic Oncology, 2015

The Crux of Molecular Prognostications in NSCLC: An Optimized Biomarker Panel Fails to Outperform Clinical Parameters

Djureinovic, Dijana; Grinberg, Marianna; Mattsson, Johanna Sofia Margareta; Edlund, Karolina et al.

Part of Journal of Thoracic Oncology, 2015

FGF2 as a potential prognostic biomarker for proneural glioma patients

Sooman, Linda; Freyhult, Eva; Jaiswal, Archita; Navani, Sanjay et al.

Part of Acta Oncologica, p. 385-394, 2015

• DOI for FGF2 as a potential prognostic biomarker for proneural glioma patients

Tissue-based map of the human proteome

Uhlen, Mathias; Fagerberg, Linn; Hallstroem, Bjoern M.; Lindskog, Cecilia et al.

Part of Science, p. 394-+, 2015

• DOI for Tissue-based map of the human proteome

Foxf2 Is Required for Brain Pericyte Differentiation and Development and Maintenance of the Blood-Brain Barrier

Reyahi, Azadeh; Nik, Ali M.; Ghiami, Mozhgan; Gritli-Linde, Amel et al.

Part of Developmental Cell, p. 19-32, 2015

• DOI for Foxf2 Is Required for Brain Pericyte Differentiation and Development and Maintenance of the Blood-Brain Barrier

Breast cancer in young women - age a risk factor only in those not given chemotherapy

Fredholm, H.; Magnusson, Kristina; Lindstrom, L. S.; Garmo, Hans et al.

Part of The Breast, 2014

• DOI for Breast cancer in young women - age a risk factor only in those not given chemotherapy

Defining the human gallbladder proteome by transcriptomics and affinity proteomics

Kampf, Caroline; Mardinoglu, Adil; Fagerberg, Linn; Hallstrom, Bjorn M. et al.

Part of Proteomics, p. 2498-2507, 2014

• DOI for Defining the human gallbladder proteome by transcriptomics and affinity proteomics

Defining the Human Adipose Tissue Proteome To Reveal Metabolic Alterations in Obesity

Mardinoglu, Adil; Kampf, Caroline; Asplund, Anna; Fagerberg, Linn et al.

Part of Journal of Proteome Research, p. 5106-5119, 2014

• DOI for Defining the Human Adipose Tissue Proteome To Reveal Metabolic Alterations in Obesity

Affinity proteomics within rare diseases: a BIO-NMD study for blood biomarkers of muscular dystrophies

Ayoglu, Burcu; Chaouch, Amina; Lochmueller, Hanns; Politano, Luisa et al.

Part of EMBO Molecular Medicine, p. 918-936, 2014

• DOI for Affinity proteomics within rare diseases: a BIO-NMD study for blood biomarkers of muscular dystrophies

Decreased decorin expression in the tumor microenvironment

Bozoky, Benedek; Savchenko, Andrii; Guven, Hayrettin; Ponten, Fredrik et al.

Part of Cancer Medicine, p. 485-491, 2014

• DOI for Decreased decorin expression in the tumor microenvironment

Peroxiredoxin-1 protects estrogen receptor alpha from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer

O'Leary, Patrick C.; Terrile, Marta; Bajor, Malgorzata; Gaj, Pawel et al.

Part of Breast Cancer Research, 2014

• DOI for Peroxiredoxin-1 protects estrogen receptor alpha from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer
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The Human Pancreas Proteome Defined by Transcriptomics and Antibody-Based Profiling

Danielsson, Angelika; Ponten, Fredrik; Fagerberg, Linn; Hallstrom, Bjorn M. et al.

Part of PLOS ONE, 2014

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WNT5A-mediated β-catenin-independent signalling is a novel regulator of cancer cell metabolism

Sherwood, Victoria; Chaurasiya, Shivendra Kumar; Ekström, Elin J; Guilmain, William et al.

Part of Carcinogenesis, p. 784-794, 2014

• DOI for WNT5A-mediated β-catenin-independent signalling is a novel regulator of cancer cell metabolism

PTPN6 expression is epigenetically regulated and influences survival and response to chemotherapy in high-grade gliomas

Sooman, Linda; Ekman, Simon; Tsakonas, Georgios; Jaiswal, Archita et al.

Part of Tumor Biology, p. 4479-4488, 2014

• DOI for PTPN6 expression is epigenetically regulated and influences survival and response to chemotherapy in high-grade gliomas

Glioma-derived macrophage migration inhibitory factor (MIF) promotes mast cell recruitment in a STAT5-dependent manner

Põlajeva, Jelena; Bergström, Tobias; Edqvist, Per-Henrik; Lundequist, Anders et al.

Part of Molecular Oncology, p. 50-58, 2014

• DOI for Glioma-derived macrophage migration inhibitory factor (MIF) promotes mast cell recruitment in a STAT5-dependent manner

Detection of enterovirus in the islet cells of patients with type 1 diabetes: what do we learn from immunohistochemistry?

Hansson, Sara F; Korsgren, Stella; Pontén, Fredrik; Korsgren, Olle

Part of Diabetologia, p. 645-646, 2014

• DOI for Detection of enterovirus in the islet cells of patients with type 1 diabetes: what do we learn from immunohistochemistry?

Aberrantly activated claudin 6 and 18.2 as potential therapy targets in non-small-cell lung cancer

Micke, Patrick; Mattsson, Johanna Sofia Margareta; Edlund, Karolina; Lohr, Miriam et al.

Part of International Journal of Cancer, p. 2206-2214, 2014

• DOI for Aberrantly activated claudin 6 and 18.2 as potential therapy targets in non-small-cell lung cancer

The Kidney Transcriptome and Proteome Defined by Transcriptomics and Antibody-Based Profiling

Habuka, Masato; Fagerberg, Linn; Hallstrom, Bjorn M.; Kampf, Caroline et al.

Part of PLOS ONE, 2014

• DOI for The Kidney Transcriptome and Proteome Defined by Transcriptomics and Antibody-Based Profiling
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Human cytomegalovirus tegument protein pp65 is detected in all intra- and extra-axial brain tumours independent of the tumour type or grade

Libard, Sylwia; Popova, Svetlana N; Amini, Rose-Marie; Kärjä, Vesa et al.

Part of PLOS ONE, 2014

• DOI for Human cytomegalovirus tegument protein pp65 is detected in all intra- and extra-axial brain tumours independent of the tumour type or grade
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The role of SATB2 as a diagnostic marker for tumors of colorectal origin: Results of a pathology-based clinical prospective study

Dragomir, Anca; de Wit, Meike; Johansson, Christine; Uhlen, Mathias et al.

Part of American Journal of Clinical Pathology, p. 630-638, 2014

• DOI for The role of SATB2 as a diagnostic marker for tumors of colorectal origin: Results of a pathology-based clinical prospective study

The human testis-specific proteome defined by transcriptomics and antibody-based profiling

Djureinovic, Dijana; Fagerberg, L.; Hallstrom, B.; Danielsson, A. et al.

Part of Molecular human reproduction, p. 476-488, 2014

• DOI for The human testis-specific proteome defined by transcriptomics and antibody-based profiling

A systematic analysis of commonly used antibodies in cancer diagnostics

Gremel, Gabriela; Bergman, Julia; Djureinovic, Dijana; Edqvist, Per-Henrik et al.

Part of Histopathology, p. 293-305, 2014

• DOI for A systematic analysis of commonly used antibodies in cancer diagnostics

The lung-specific proteome defined by integration of transcriptomics and antibody-based profiling

Lindskog, Cecilia; Fagerberg, Linn; Hallstrom, Bjorn; Edlund, Karolina et al.

Part of The FASEB Journal, p. 5184-5196, 2014

• DOI for The lung-specific proteome defined by integration of transcriptomics and antibody-based profiling

Antibody validation of immunohistochemistry for biomarker discovery: Recommendations of a consortium of academic and pharmaceutical based histopathology researchers

Howat, William J; Lewis, Arthur; Jones, Phillipa; Kampf, Caroline et al.

Part of Methods, p. 34-38, 2014

• DOI for Antibody validation of immunohistochemistry for biomarker discovery: Recommendations of a consortium of academic and pharmaceutical based histopathology researchers
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The human liver-specific proteome defined by transcriptomics and antibody-based profiling

Kampf, Caroline; Mardinoglu, Adil; Fagerberg, Linn; Hallstrom, Bjorn M. et al.

Part of The FASEB Journal, p. 2901-2914, 2014

• DOI for The human liver-specific proteome defined by transcriptomics and antibody-based profiling

Molecular- and organelle-based predictive paradigm underlying recovery by left ventricular assist device support

Liem, David A; Nsair, Ali; Setty, Shaun P; Cadeiras, Martin et al.

Part of Circulation Heart Failure, p. 359-366, 2014

• DOI for Molecular- and organelle-based predictive paradigm underlying recovery by left ventricular assist device support

Analysis of Candidate Genes for Lineage-Specific Expression Changes in Humans and Primates

Lindskog, Cecilia; Kuhlwilm, Martin; Davierwala, Armaity; Fu, Ning et al.

Part of Journal of Proteome Research, p. 3596-3606, 2014

• DOI for Analysis of Candidate Genes for Lineage-Specific Expression Changes in Humans and Primates

Subtyping of gliomas of various WHO grades by the application of immunohistochemistry

Popova, Svetlana N; Bergqvist, Michael; Dimberg, Anna; Edqvist, Per-Henrik et al.

Part of Histopathology, p. 365-379, 2014

• DOI for Subtyping of gliomas of various WHO grades by the application of immunohistochemistry

A study of embryonic stem cell-related proteins in human astrocytomas: Identification of Nanog as a predictor of survival

Elsir, Tamador; Edqvist, Per-Henrik; Carlson, Joseph; Ribom, Dan et al.

Part of International Journal of Cancer, p. 1123-1131, 2014

• DOI for A study of embryonic stem cell-related proteins in human astrocytomas: Identification of Nanog as a predictor of survival

Evidence for a morphologically distinct and functionally robust cell type in the proximal tubules of human kidney

Hansson, Jennifer; Hultenby, Kjell; Cramnert, Catharina; Pontén, Fredrik et al.

Part of Human Pathology, p. 382-393, 2014

• DOI for Evidence for a morphologically distinct and functionally robust cell type in the proximal tubules of human kidney

Investigation of molecular alterations of AKT-3 in triple-negative breast cancer

O'Hurley, Gillian; Daly, Etáin; O'Grady, Anthony; Cummins, Robert et al.

Part of Histopathology, p. 660-670, 2014

• DOI for Investigation of molecular alterations of AKT-3 in triple-negative breast cancer

Detection of the human endogenous retrovirus ERV3-encoded Env-protein in human tissues using antibody-based proteomics

Fei, Chen; Atterby, Christina; Edqvist, Per-Henrik; Pontén, Fredrik et al.

Part of Journal of the Royal Society of Medicine, p. 22-29, 2014

• DOI for Detection of the human endogenous retrovirus ERV3-encoded Env-protein in human tissues using antibody-based proteomics

Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics

Fagerberg, Linn; Hallström, Björn M; Oksvold, Per; Kampf, Caroline et al.

Part of Molecular & Cellular Proteomics, p. 397-406, 2014

• DOI for Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics

Colorectal cancer candidate biomarkers identified by tissue secretome proteome profiling

de Wit, Meike; Kant, Huub; Piersma, Sander R.; Pham, Thang V. et al.

Part of Journal of Proteomics, p. 26-39, 2014

• DOI for Colorectal cancer candidate biomarkers identified by tissue secretome proteome profiling

Antibody performance in western blot applications is context-dependent

Algenas, Cajsa; Agaton, Charlotta; Fagerberg, Linn; Asplund, Anna et al.

Part of Biotechnology Journal, p. 435-445, 2014

• DOI for Antibody performance in western blot applications is context-dependent

Contribution of Antibody-based Protein Profiling to the Human Chromosome-centric Proteome Project (C-HPP)

Fagerberg, Linn; Oksvold, Per; Skogs, Marie; Algenäs, Cajsa et al.

Part of Journal of Proteome Research, p. 2439-2448, 2013

• DOI for Contribution of Antibody-based Protein Profiling to the Human Chromosome-centric Proteome Project (C-HPP)

Systematic antibody generation and validation via tissue microarray technology leading to identification of a novel protein prognostic panel in breast cancer

O'Leary, Patrick C.; Penny, Sarah A.; Dolan, Roisin T.; Kelly, Catherine M. et al.

Part of BMC Cancer, 2013

• DOI for Systematic antibody generation and validation via tissue microarray technology leading to identification of a novel protein prognostic panel in breast cancer
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In situ Protein Detection for Companion Diagnostics

Gremel, Gabriela; Grannas, Karin; Sutton, Lesley Ann; Pontén, Fredrik et al.

Part of Frontiers in Oncology, 2013

• DOI for In situ Protein Detection for Companion Diagnostics

Biomarker discovery in non-small cell lung cancer: integrating gene expression profiling, meta-analysis and tissue microarray validation

Botling, Johan; Edlund, Karolina; Lohr, Miriam; Hellwig, Birte et al.

Part of Clinical Cancer Research, p. 194-204, 2013

• DOI for Biomarker discovery in non-small cell lung cancer: integrating gene expression profiling, meta-analysis and tissue microarray validation

Expression of the actin-binding protein Anillin is a prognostic biomarker for primary ER positive breast cancer.

Magnusson, Kristina; Gremel, Gabriela; Ponten, Fredrik; Jirstrom, Karin

Part of Cancer Research, 2013

• DOI for Expression of the actin-binding protein Anillin is a prognostic biomarker for primary ER positive breast cancer.

The prognostic relevance of tumour-infiltrating plasma cells and immunoglobulin kappa C indicates an important role of the humoral immune response in non-small cell lung cancer

Lohr, Miriam; Edlund, Karolina; Botling, Johan; Hammad, Seddik et al.

Part of Cancer Letters, p. 222-228, 2013

• DOI for The prognostic relevance of tumour-infiltrating plasma cells and immunoglobulin kappa C indicates an important role of the humoral immune response in non-small cell lung cancer

European H16N3 Gull Influenza Virus Attaches to the Human Respiratory Tract and Eye

Lindskog, Cecilia; Ellström, Patrik; Olsen, Björn; Pontén, Fredrik et al.

Part of PLOS ONE, 2013

• DOI for European H16N3 Gull Influenza Virus Attaches to the Human Respiratory Tract and Eye
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Vandetanib combined with a p38 MAPK inhibitor synergistically reduces glioblastoma cell survival

Sooman, Linda; Lennartsson, Johan; Gullbo, Joachim; Bergqvist, Michael et al.

Part of Medical Oncology, p. 638, 2013

• DOI for Vandetanib combined with a p38 MAPK inhibitor synergistically reduces glioblastoma cell survival

A Texture Based Pattern Recognition Approach to Distinguish Melanoma from Non-Melanoma Cells in Histopathological Tissue Microarray Sections

Rexhepaj, Elton; Agnarsdóttir, Margrét; Bergman, Julia; Edqvist, Per-Henrik et al.

Part of PLOS ONE, 2013

• DOI for A Texture Based Pattern Recognition Approach to Distinguish Melanoma from Non-Melanoma Cells in Histopathological Tissue Microarray Sections
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The protein phosphatase 2 subunit PR48 is a novel melanoma tumor suppressor gene.

van Kempen, Leon C. L.; Jarry, Jonathan; Elchebly, Mounib; Redpath, Margaret et al.

Part of Cancer Research, 2013

• DOI for The protein phosphatase 2 subunit PR48 is a novel melanoma tumor suppressor gene.

Estrogen receptor expression induces changes in the microRNA pool in human colon cancer cells

Edvardsson, Karin; Nguyen-Vu, Trang; Kalasekar, Sharanya M.; Pontén, Fredrik et al.

Part of Carcinogenesis, p. 1431-1441, 2013

• DOI for Estrogen receptor expression induces changes in the microRNA pool in human colon cancer cells

Enteroviruses and the pathogenesis of type 1 diabetes revisited: cross-reactivity of enterovirus capsid protein (VP1) antibodies with human mitochondrial proteins

Hansson, Sara F.; Korsgren, Stella; Pontén, Fredrik; Korsgren, Olle

Part of Journal of Pathology, p. 719-728, 2013

• DOI for Enteroviruses and the pathogenesis of type 1 diabetes revisited: cross-reactivity of enterovirus capsid protein (VP1) antibodies with human mitochondrial proteins

Progesterone receptor negativity is an independent risk factor for relapse in patients with early stage endometrioid endometrial adenocarcinoma

Huvila, Jutta; Talve, Lauri; Carpen, Olli; Edqvist, Per-Henrik et al.

Part of Gynecologic Oncology, p. 463-469, 2013

• DOI for Progesterone receptor negativity is an independent risk factor for relapse in patients with early stage endometrioid endometrial adenocarcinoma

Majority of differentially expressed genes are down-regulated during malignant transformation in a four-stage model

Danielsson, Frida; Skogs, Marie; Huss, Mikael; Rexhepaj, Elton et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 6853-6858, 2013

• DOI for Majority of differentially expressed genes are down-regulated during malignant transformation in a four-stage model

CDK-mediated activation of the SCFFBXO28 ubiquitin ligase promotes MYC-driven transcription and tumourigenesis and predicts poor survival in breast cancer

Cepeda, Diana; Ng, Hwee-Fang; Sharifi, Hamid Reza; Mahmoudi, Salah et al.

Part of EMBO Molecular Medicine, p. 1067-1086, 2013

• DOI for CDK-mediated activation of the SCFFBXO28 ubiquitin ligase promotes MYC-driven transcription and tumourigenesis and predicts poor survival in breast cancer
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Increased expression of heparanase in symptomatic carotid atherosclerosis

Österholm, C.; Folkersen, L.; Lengquist, M.; Pontén, Fredrik et al.

Part of Atherosclerosis, p. 67-73, 2013

• DOI for Increased expression of heparanase in symptomatic carotid atherosclerosis

Foxf2 in Intestinal Fibroblasts Reduces Numbers of Lgr5(+) Stem Cells and Adenoma Formation by Inhibiting Wnt Signaling

Nik, Ali Moussavi; Reyahi, Azadeh; Pontén, Fredrik; Carlsson, Peter

Part of Gastroenterology, p. 1001-1011, 2013

• DOI for Foxf2 in Intestinal Fibroblasts Reduces Numbers of Lgr5(+) Stem Cells and Adenoma Formation by Inhibiting Wnt Signaling

Antibodies Biotinylated Using a Synthetic Z-domain from Protein A Provide Stringent In Situ Protein Detection

Andersson, Sandra; Konrad, Anna; Ashok, Nikhil; Pontén, Fredrik et al.

Part of Journal of Histochemistry and Cytochemistry, p. 773-784, 2013

• DOI for Antibodies Biotinylated Using a Synthetic Z-domain from Protein A Provide Stringent In Situ Protein Detection

Profiling of Atherosclerotic Lesions by Gene and Tissue Microarrays Reveals PCSK6 as a Novel Protease in Unstable Carotid Atherosclerosis

Perisic, Ljubica; Hedin, Erika; Razuvaev, Anton; Lengquist, Mariette et al.

Part of Arteriosclerosis, Thrombosis and Vascular Biology, p. 2432-2443, 2013

• DOI for Profiling of Atherosclerotic Lesions by Gene and Tissue Microarrays Reveals PCSK6 as a Novel Protease in Unstable Carotid Atherosclerosis

Improving the Diagnosis and Management of Neuroendocrine Tumors: Utilizing New Advances in Biomarker and Molecular Imaging Science

Giandomenico, Valeria; Modlin, Irvin M.; Pontén, Fredrik; Nilsson, Mats et al.

Part of Neuroendocrinology, p. 16-30, 2013

• DOI for Improving the Diagnosis and Management of Neuroendocrine Tumors: Utilizing New Advances in Biomarker and Molecular Imaging Science

Identifying Prognostically Relevant Subsets of Endometrial Cancer Using Unsupervised Clustering of Immunohistochemical Staining Data

Huvila, J.; Laajala, D.; Edvist, P. H.; Talve, L. et al.

Part of International Journal of Gynecological Cancer, 2013

Novel signatures of cancer-associated fibroblasts

Bozóky, Benedek; Savchenko, Andrii; Csermely, Péter; Korcsmáros, Tamás et al.

Part of International Journal of Cancer, p. 286-293, 2013

• DOI for Novel signatures of cancer-associated fibroblasts

Production of tissue microarrays, immunohistochemistry staining and digitalization within the human protein atlas

Kampf, Caroline; Olsson, Ingmarie; Ryberg, Urban; Sjöstedt, Evelina et al.

Part of Journal of Visualized Experiments, 2012

• DOI for Production of tissue microarrays, immunohistochemistry staining and digitalization within the human protein atlas
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The presence of tumor associated macrophages in tumor stroma as a prognostic marker for breast cancer patients

Medrek, Catharina; Pontén, Fredrik; Jirstrom, Karin; Leandersson, Karin

Part of BMC Cancer, p. 306, 2012

• DOI for The presence of tumor associated macrophages in tumor stroma as a prognostic marker for breast cancer patients
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A tool to facilitate clinical biomarker studies - a tissue dictionary based on the Human Protein Atlas

Kampf, Caroline; Bergman, Julia; Oksvold, Per; Asplund, Anna et al.

Part of BMC Medicine, p. 103, 2012

• DOI for A tool to facilitate clinical biomarker studies - a tissue dictionary based on the Human Protein Atlas
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Transcriptional profiling of human glioblastoma vessels indicates a key role of VEGF-A and TGFβ2 in vascular abnormalization

Dieterich, Lothar C.; Mellberg, Sofie; Langenkamp, Elise; Zhang, Lei et al.

Part of Journal of Pathology, p. 378-390, 2012

• DOI for Transcriptional profiling of human glioblastoma vessels indicates a key role of VEGF-A and TGFβ2 in vascular abnormalization

CD99 is a novel prognostic stromal marker in non-small cell lung cancer

Edlund, Karolina; Lindskog, Cecilia; Saito, Akira; Berglund, Anders et al.

Part of International Journal of Cancer, p. 2264-2273, 2012

• DOI for CD99 is a novel prognostic stromal marker in non-small cell lung cancer

Paladin (X99384) is expressed in the vasculature and shifts from endothelial to vascular smooth muscle cells during mouse development

Wallgard, Elisabet; Nitzsche, Anja; Larsson, Jimmy; Guo, Xiaoyuan et al.

Part of Developmental Dynamics, p. 770-786, 2012

• DOI for Paladin (X99384) is expressed in the vasculature and shifts from endothelial to vascular smooth muscle cells during mouse development

Scalable In Situ Hybridization on Tissue Arrays for Validation of Novel Cancer and Tissue-Specific Biomarkers

Kiflemariam, Sara; Andersson, Sandra; Asplund, Anna; Pontén, Fredrik et al.

Part of PLOS ONE, 2012

• DOI for Scalable In Situ Hybridization on Tissue Arrays for Validation of Novel Cancer and Tissue-Specific Biomarkers
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GABA-A Channel Subunit Expression in Human Glioma Correlates with Tumor Histology and Clinical Outcome

Smits, Anja; Jin, Zhe; Elsir, Tamador; Pedder, Hugo et al.

Part of PLOS ONE, 2012

• DOI for GABA-A Channel Subunit Expression in Human Glioma Correlates with Tumor Histology and Clinical Outcome
• Download full text (pdf) of GABA-A Channel Subunit Expression in Human Glioma Correlates with Tumor Histology and Clinical Outcome

Novel pancreatic beta cell-specific proteins: Antibody-based proteomics for identification of new biomarker candidates

Lindskog, Cecilia; Korsgren, Olle; Pontén, Fredrik; Eriksson, Jan W et al.

Part of Journal of Proteomics, p. 2611-2620, 2012

• DOI for Novel pancreatic beta cell-specific proteins: Antibody-based proteomics for identification of new biomarker candidates

Cell surface proteomics identifies glucose transporter type 1 and prion protein as candidate biomarkers for colorectal adenoma-to-carcinoma progression

de Wit, Meike; Jimenez, Connie R; Carvalho, Beatriz; Belien, Jeroen A M et al.

Part of Gut, p. 855-864, 2012

• DOI for Cell surface proteomics identifies glucose transporter type 1 and prion protein as candidate biomarkers for colorectal adenoma-to-carcinoma progression

Antibody-based Protein Profiling of the Human Chromosome 21

Uhlén, Mathias; Oksvold, Per; Algenäs, Cajsa; Hamsten, Carl et al.

Part of Molecular & Cellular Proteomics, 2012

• DOI for Antibody-based Protein Profiling of the Human Chromosome 21

BCL2L1 has a functional role in colorectal cancer and its protein expression is associated with chromosome 20q gain

Sillars-Hardebol, Anke H.; Carvalho, Beatriz; Belien, Jeroen A. M.; de Wit, Meike et al.

Part of Journal of Pathology, p. 442-450, 2012

• DOI for BCL2L1 has a functional role in colorectal cancer and its protein expression is associated with chromosome 20q gain

CSE1L, DIDO1 and RBM39 in colorectal adenoma to carcinoma progression

Sillars-Hardebol, Anke H.; Carvalho, Beatriz; Belien, Jeroen A. M.; de Wit, Meike et al.

Part of Cellular Oncology, p. 293-300, 2012

• DOI for CSE1L, DIDO1 and RBM39 in colorectal adenoma to carcinoma progression

TPX2 and AURKA promote 20q amplicon-driven colorectal adenoma to carcinoma progression

Sillars-Hardebol, Anke H; Carvalho, Beatriz; Tijssen, Marianne; Beliën, Jeroen A M et al.

Part of Gut, p. 1568-1575, 2012

• DOI for TPX2 and AURKA promote 20q amplicon-driven colorectal adenoma to carcinoma progression

Peroxiredoxin-1 Protects Against Oncogene-induced Suppression of the Estrogen Receptor and is a Biomarker of Favourable Prognosis in Estrogen Receptor-positive Breast Cancer

O'Leary, P. C.; Brennan, D. J.; O'Connor, D. P.; Hennessy, B. T. et al.

Part of European Journal of Cancer, 2012

• DOI for Peroxiredoxin-1 Protects Against Oncogene-induced Suppression of the Estrogen Receptor and is a Biomarker of Favourable Prognosis in Estrogen Receptor-positive Breast Cancer

SATB2 is an Independent Predictor of Outcome in Colorectal Cancer

Naicker, K.; Brennan, D. J.; Klinger, R.; Pontén, Fredrik et al.

Part of European Journal of Cancer, 2012

• DOI for SATB2 is an Independent Predictor of Outcome in Colorectal Cancer

Low RBM3 protein expression correlates with tumour progression and poor prognosis in malignant melanoma: An analysis of 215 cases from the Malmo Diet and Cancer Study

Jonsson, Liv; Bergman, Julia; Nodin, Björn; Manjer, Jonas et al.

Part of Journal of Translational Medicine, p. 114, 2011

• DOI for Low RBM3 protein expression correlates with tumour progression and poor prognosis in malignant melanoma: An analysis of 215 cases from the Malmo Diet and Cancer Study

Tumor-specific HMG-CoA reductase expression in primary premenopausal breast cancer predicts response to tamoxifen

Brennan, Donal J.; Laursen, Henriette; O'Connor, Darran P.; Borgquist, Signe et al.

Part of Breast Cancer Research, 2011

• DOI for Tumor-specific HMG-CoA reductase expression in primary premenopausal breast cancer predicts response to tamoxifen

RBM3-regulated genes promote DNA integrity and affect clinical outcome in epithelial ovarian cancer

Ehlén, Åsa; Nodin, Björn; Rexhepaj, Elton; Brändstedt, Jenny et al.

Part of Translational Oncology, p. 212-221, 2011

Human tumors instigate granulin-expressing hematopoietic cells that promote malignancy by activating stromal fibroblasts in mice

Elkabets, Moshe; Gifford, Ann M.; Scheel, Christina; Nilsson, Björn et al.

Part of Journal of Clinical Investigation, p. 784-799, 2011

• DOI for Human tumors instigate granulin-expressing hematopoietic cells that promote malignancy by activating stromal fibroblasts in mice

Large-Scale Protein Profiling in Human Cell Lines Using Antibody-Based Proteomics

Fagerberg, Linn; Strömberg, Sara; El-Obeid, Adila; Gry, Marcus et al.

Part of Journal of Proteome Research, p. 4066-4075, 2011

• DOI for Large-Scale Protein Profiling in Human Cell Lines Using Antibody-Based Proteomics

Functional and prognostic relevance of the homeobox protein MSX2 in malignant melanoma

Gremel, G.; Ryan, D.; Rafferty, M.; Lanigan, F. et al.

Part of British Journal of Cancer, p. 565-574, 2011

• DOI for Functional and prognostic relevance of the homeobox protein MSX2 in malignant melanoma

Diagnostic biomarkers of prostate cancer

Häggarth, Lars; Hägglöf, Christina; Jaraj, Sara Jonmarker; Wester, Kenneth et al.

Part of Scandinavian Journal of Urology and Nephrology, p. 60-67, 2011

• DOI for Diagnostic biomarkers of prostate cancer

GAD1 is a biomarker for benign and malignant prostatic tissue

Jaraj, Sara Jonmarker; Augsten, Martin; Häggarth, Lars; Wester, Kenneth et al.

Part of Scandinavian Journal of Urology and Nephrology, p. 39-45, 2011

• DOI for GAD1 is a biomarker for benign and malignant prostatic tissue

SATB2 in Combination With Cytokeratin 20 Identifies Over 95% of all Colorectal Carcinomas

Magnusson, Kristina; de Wit, Meike; Brennan, Donal J.; Johnson, Louis B. et al.

Part of American Journal of Surgical Pathology, p. 937-948, 2011

• DOI for SATB2 in Combination With Cytokeratin 20 Identifies Over 95% of all Colorectal Carcinomas

Sun-Induced Nonsynonymous p53 Mutations Are Extensively Accumulated and Tolerated in Normal Appearing Human Skin

Ståhl, Patrik L.; Stranneheim, Henrik; Asplund, Anna; Berglund, Lisa et al.

Part of Journal of Investigative Dermatology, p. 504-508, 2011

• DOI for Sun-Induced Nonsynonymous p53 Mutations Are Extensively Accumulated and Tolerated in Normal Appearing Human Skin

Growth differentiation factor 15: a prognostic marker for recurrence in colorectal cancer

Wallin, Ulrik; Glimelius, Bengt; Jirström, K.; Darmanis, Spyros et al.

Part of British Journal of Cancer, p. 1619-1627, 2011

• DOI for Growth differentiation factor 15: a prognostic marker for recurrence in colorectal cancer

Generation of monospecific antibodies based on affinity capture of polyclonal antibodies

Hjelm, Barbara; Forsström, Bjorn; Igel, Ulrika; Johannesson, Henrik et al.

Part of Protein Science, p. 1824-1835, 2011

• DOI for Generation of monospecific antibodies based on affinity capture of polyclonal antibodies

High nuclear RBM3 expression is associated with an improved prognosis in colorectal cancer

Hjelm, Barbara; Brennan, Donal J.; Zendehrokh, Nooreldin; Eberhard, Jakob et al.

Part of Proteomics Clinical Applications, p. 624-635, 2011

• DOI for High nuclear RBM3 expression is associated with an improved prognosis in colorectal cancer

Tumour-specific HMG-CoAR is an independent predictor of recurrence free survival in epithelial ovarian cancer

Brennan, Donal J.; Brändstedt, Jenny; Rexhepaj, Elton; Foley, Michael et al.

Part of BMC Cancer, p. 125, 2010

• DOI for Tumour-specific HMG-CoAR is an independent predictor of recurrence free survival in epithelial ovarian cancer

Expression of the RNA-binding protein RBM3 is associated with a favourable prognosis and cisplatin sensitivity in epithelial ovarian cancer

Ehlén, Åsa; Brennan, Donal J.; Nodin, Björn; O'Connor, Darran P. et al.

Part of Journal of Translational Medicine, p. 78, 2010

• DOI for Expression of the RNA-binding protein RBM3 is associated with a favourable prognosis and cisplatin sensitivity in epithelial ovarian cancer

Tissue-specific protein expression in human cells. tissues end organs

Gry, Markus; Oksvold, P; Pontén, Fredrik; Uhlén, Mathias

Part of Journal of Proteomics and Bioinformatics, p. 286-293, 2010

• DOI for Tissue-specific protein expression in human cells. tissues end organs

SOX10 expression in superficial spreading and nodular malignant melanomas

Agnarsdóttir, Margrét; Sooman, Linda; Bolander, Åsa; Strömberg, Sara et al.

Part of Melanoma research, p. 468-478, 2010

• DOI for SOX10 expression in superficial spreading and nodular malignant melanomas

Molecular profiling using tissue microarrays as a tool to identify predictive biomarkers in laryngeal cancer treated with radiotherapy

Holgersson, Georg; Ekman, Simon; Reizenstein, Johan; Bergqvist, Michael et al.

Part of Cancer Genomics & Proteomics, p. 1-7, 2010

International network of cancer genome projects

Hudson, Thomas J.; Pontén, Fredrik; Yang, Huanming; International Cancer Genome Consortium, undefined

Part of Nature, p. 993-998, 2010

• DOI for International network of cancer genome projects

The impact of tissue fixatives on morphology and antibody-based protein profiling in tissues and cells

Paavilainen, Linda; Edvinsson, Åsa; Asplund, Anna; Hober, Sophia et al.

Part of Journal of Histochemistry and Cytochemistry, p. 237-246, 2010

• DOI for The impact of tissue fixatives on morphology and antibody-based protein profiling in tissues and cells

Topoisomerase I Amplification in Melanoma is Associated with More Advanced Tumours and Poor Prognosis

Ryan, Denise; Rafferty, Mairin; Hegarty, Shauna; O´Leary, Patrick et al.

Part of Pigment Cell and Melanoma Research, p. 542-553, 2010

• DOI for Topoisomerase I Amplification in Melanoma is Associated with More Advanced Tumours and Poor Prognosis

Toward Next Generation Plasma Profiling via Heat-induced Epitope Retrieval and Array-based Assays

Schwenk, Jochen M.; Igel, Ulrika; Neiman, Maja; Langen, Hanno et al.

Part of Molecular & Cellular Proteomics, p. 2497-2507, 2010

• DOI for Toward Next Generation Plasma Profiling via Heat-induced Epitope Retrieval and Array-based Assays

Immunohistochemical detection of tyrosine phosphatase SHP-1 predicts outcome after radical prostatectomy for localized prostate cancer

Tassidis, Helena; Brokken, Leon J. S.; Jirström, Karin; Ehrnström, Roy et al.

Part of International Journal of Cancer, p. 2296-2307, 2010

• DOI for Immunohistochemical detection of tyrosine phosphatase SHP-1 predicts outcome after radical prostatectomy for localized prostate cancer

Towards a knowledge-based Human Protein Atlas

Uhlén, Mathias; Oksvold, Per; Fagerberg, Linn; Lundberg, Emma et al.

Part of Nature Biotechnology, p. 1248-1250, 2010

• DOI for Towards a knowledge-based Human Protein Atlas

Antibody-based proteomics for discovery and exploration of proteins expressed in pancreatic islets

Lindskog, Cecilia; Asplund, Anna; Engkvist, Margareta; Pontén, Fredrik et al.

Part of Discovery Medicine, p. 565-578, 2010

Correlations between RNA and protein expression profiles in 23 human cell lines

Gry, Marcus; Rimini, Rebecca; Strömberg, Sara; Asplund, Anna et al.

Part of BMC Genomics, p. 365, 2009

• DOI for Correlations between RNA and protein expression profiles in 23 human cell lines

Pulmonary Autoimmunity as a Feature of Autoimmune Polyendocrine Syndrome Type 1 and Identification of KCNRG as a Bronchial Autoantigen

Alimohammadi, Mohammad; Dubois, Noemie; Sköldberg, Filip; Hallgren, Åsa et al.

Part of Proceedings of the National Academy of Sciences of the United States of America, p. 4396-4401, 2009

• DOI for Pulmonary Autoimmunity as a Feature of Autoimmune Polyendocrine Syndrome Type 1 and Identification of KCNRG as a Bronchial Autoantigen

High expression of tumour-associated trypsin inhibitor correlates with liver metastasis and poor prognosis in colorectal cancer

Gaber, A.; Johansson, M.; Stenman, U-H.; Hotakainen, K. et al.

Part of British Journal of Cancer, p. 1540-1548, 2009

• DOI for High expression of tumour-associated trypsin inhibitor correlates with liver metastasis and poor prognosis in colorectal cancer

The prognostic significance of tryptophanyl-tRNA synthetase in colorectal cancer

Ghanipour, Arezo; Jirström, Karin; Pontén, Fredrik; Glimelius, Bengt et al.

Part of Cancer Epidemiology, Biomarkers and Prevention, p. 2949-2956, 2009

• DOI for The prognostic significance of tryptophanyl-tRNA synthetase in colorectal cancer

Nuclear expression of the RNA-binding protein RBM3 is associated with an improved clinical outcome in breast cancer

Jögi, Annika; Brennan, Donal J; Rydén, Lisa; Magnusson, Kristina et al.

Part of Modern Pathology, p. 1564-1574, 2009

• DOI for Nuclear expression of the RNA-binding protein RBM3 is associated with an improved clinical outcome in breast cancer

ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth

Markljung, Ellen; Jiang, Lin; Jaffe, Jacob D.; Mikkelsen, Tarjei S. et al.

Part of PLoS biology, 2009

• DOI for ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth

Prognostic significance of stromal platelet-derived growth factor beta-receptor expression in human breast cancer

Paulsson, Janna; Sjöblom, Tobias; Micke, Patrick; Pontén, Fredrik et al.

Part of American Journal of Pathology, p. 334-341, 2009

• DOI for Prognostic significance of stromal platelet-derived growth factor beta-receptor expression in human breast cancer

A global view of protein expression in human cells, tissues, and organs

Pontén, Fredrik; Gry, Marcus; Fagerberg, Linn; Lundberg, Emma et al.

Part of Molecular Systems Biology, p. 337, 2009

• DOI for A global view of protein expression in human cells, tissues, and organs

Recommendations from the 2008 International Summit on Proteomics Data Release and Sharing Policy: the Amsterdam principles.

Rodriguez, Henry; Snyder, Mike; Uhlén, Mathias; Andrews, Phil et al.

Part of Journal of Proteome Research, p. 3689-3692, 2009

• DOI for Recommendations from the 2008 International Summit on Proteomics Data Release and Sharing Policy: the Amsterdam principles.

Selective expression of Syntaxin-7 protein in benign melanocytes and malignant melanoma

Strömberg, Sara; Agnarsdóttir, Margrét; Magnusson, Kristina; Rexhepaj, Elton et al.

Part of Journal of Proteome Research, p. 1639-1646, 2009

• DOI for Selective expression of Syntaxin-7 protein in benign melanocytes and malignant melanoma

Extensive expression of craniofacial related homeobox genes in canine mammary sarcomas

Wensman, Helena; Göransson, Hanna; Leuchowius, Karl-Johan; Strömberg, Sara et al.

Part of Breast Cancer Research and Treatment, p. 333-343, 2009

• DOI for Extensive expression of craniofacial related homeobox genes in canine mammary sarcomas

DLG3/SAP102 protein expression in malformations of cortical development: A study of human epileptic cortex by tissue microarray

Qu, Mingqi; Aronica, Eleonora; Boer, Karin; Fällmar, David et al.

Part of Epilepsy Research, p. 33-41, 2009

• DOI for DLG3/SAP102 protein expression in malformations of cortical development: A study of human epileptic cortex by tissue microarray

Herbal melanin activates TLR4/NF-kappaB signaling pathway

Öberg, Fredrik; Haseeb, Adil; Ahnfelt, Matilda; Pontén, Fredrik et al.

Part of Phytomedicine, p. 477-84, 2009

• DOI for Herbal melanin activates TLR4/NF-kappaB signaling pathway

Intercalated discs: multiple proteins perform multiple functions in non-failing and failing human hearts

Estigoy, Colleen; Pontén, Fredrik; Odeberg, Jacob; Guilhaus, Michael et al.

Part of Biophysical Reviews, p. 43-49, 2009

• DOI for Intercalated discs: multiple proteins perform multiple functions in non-failing and failing human hearts

Evaluation of monospecific antibodies: a comparison study with commercial analogs using immunohistochemistry on tissue microarrays

Paavilainen, Linda; Wernérus, Henrik; Nilsson, Peter; Uhlén, Mathias et al.

Part of Applied immunohistochemistry & molecular morphology (Print), p. 493-502, 2008

• DOI for Evaluation of monospecific antibodies: a comparison study with commercial analogs using immunohistochemistry on tissue microarrays

Prognostic impact of tumour-specific HMG-CoA reductase expression in primary breast cancer

Borgquist, Signe; Jögi, Annika; Pontén, Fredrik; Rydén, Lisa et al.

Part of Breast Cancer Research, 2008

• DOI for Prognostic impact of tumour-specific HMG-CoA reductase expression in primary breast cancer

Serological and immunohistochemical analysis of S100 and derivatives as markers for prognosis of newly operated malignant melanoma patients

Bolander, Åsa; Agnarsdóttir, Margrét; Wagenius, Gunnar; Strömberg, Sara et al.

Part of Melanoma research, p. 412-419, 2008

• DOI for Serological and immunohistochemical analysis of S100 and derivatives as markers for prognosis of newly operated malignant melanoma patients

The correlation between cellular size and protein expression levels--normalization for global protein profiling

Lundberg, Emma; Gry, Marcus; Oksvold, Per; Kononen, Juha et al.

Part of Journal of proteomics, p. 448-460, 2008

• DOI for The correlation between cellular size and protein expression levels--normalization for global protein profiling

A cis-acting regulatory mutation causes premature hair graying and susceptibility to melanoma in the horse

Pielberg, Gerli Rosengren; Golovko, Anna; Sundström, Elisabeth; Curik, Ino et al.

Part of Nature Genetics, p. 1004-1009, 2008

• DOI for A cis-acting regulatory mutation causes premature hair graying and susceptibility to melanoma in the horse

A web-based tool for in silico biomarker discovery based on tissue-specific protein profiles in normal and cancer tissues

Björling, Erik; Lindskog, Cecilia; Oksvold, Per; Linné, Jerker et al.

Part of Molecular & Cellular Proteomics, p. 825-844, 2008

• DOI for A web-based tool for in silico biomarker discovery based on tissue-specific protein profiles in normal and cancer tissues

Expression profiling of microdissected cell populations selected from basal cells in normal epidermis and basal cell carcinoma

Asplund, Anna; Gry Björklund, M.; Sundquist, C.; Strömberg, Sara et al.

Part of British Journal of Dermatology, p. 527-38, 2008

• DOI for Expression profiling of microdissected cell populations selected from basal cells in normal epidermis and basal cell carcinoma

Toward a confocal subcellular atlas of the human proteome

Barbe, Laurent; Lundberg, Emma; Oksvold, Per; Stenius, Anna et al.

Part of Molecular & Cellular Proteomics, p. 499-508, 2008

• DOI for Toward a confocal subcellular atlas of the human proteome

The protein expression of TRP-1 and galectin-1 in cutaneous malignant melanomas

Bolander, Åsa; Agnarsdóttir, Margrét; Strömberg, Sara; Pontén, Fredrik et al.

Part of Cancer Genomics & Proteomics, p. 293-300, 2008

HMG-CoA reductase expression in breast cancer is associated with a less aggressive phenotype and influenced by anthropometric factors

Borgquist, Signe; Djerbi, Soraya; Pontén, Fredrik; Anagnostaki, Lola et al.

Part of International Journal of Cancer, p. 1146-53, 2008

• DOI for HMG-CoA reductase expression in breast cancer is associated with a less aggressive phenotype and influenced by anthropometric factors

The Human Protein Atlas: a tool for pathology

Pontén, Fredrik; Jirström, K.; Uhlen, M.

Part of Journal of Pathology, p. 387-93, 2008

• DOI for The Human Protein Atlas: a tool for pathology

Transcriptional profiling of melanocytes from patients with vitiligo vulgaris

Strömberg, Sara; Gry Björklund, Marcus; Asplund, Anna; Rimini, Rebecca et al.

Part of Pigment Cell and Melanoma Research, p. 162-171, 2008

• DOI for Transcriptional profiling of melanocytes from patients with vitiligo vulgaris

A high-throughput strategy for protein profiling in cell microarrays using automated image analysis

Strömberg, Sara; Gry Björklund, Marcus; Asplund, Caroline; Sköllermo, Anna et al.

Part of Proteomics, p. 2142-2150, 2007

• DOI for A high-throughput strategy for protein profiling in cell microarrays using automated image analysis

In Situ Identification of Genes Regulated Specifically in Fibroblasts of Human Basal Cell Carcinoma

Micke, Patrick; Kappert, Kai; Ohshima, Mitsuhiro; Sundquist, Christina et al.

Part of Journal of Investigative Dermatology, p. 1516-1523, 2007

• DOI for In Situ Identification of Genes Regulated Specifically in Fibroblasts of Human Basal Cell Carcinoma

Sox10 Has a Broad Expression Pattern in Gliomas and Enhances Platelet-Derived Growth Factor-B–Induced Gliomagenesis

Ferletta, Maria; Uhrbom, Lene; Olofsson, Tommie; Pontén, Fredrik et al.

Part of Molecular Cancer Research, p. 891-897, 2007

• DOI for Sox10 Has a Broad Expression Pattern in Gliomas and Enhances Platelet-Derived Growth Factor-B–Induced Gliomagenesis

The RBCC Gene RFP2 (Leu5) Encodes a Novel Transmembrane E3 Ubiquitin Ligase Involved in ERAD

Lerner, Mikael; Corcoran, Martin; Cepeda, Diana; Nielsen, Michael L. et al.

Part of Molecular Biology of the Cell, p. 1670-1682, 2007

• DOI for The RBCC Gene RFP2 (Leu5) Encodes a Novel Transmembrane E3 Ubiquitin Ligase Involved in ERAD

Systematically generated antibodies against human gene products: High throughput screening on sections from the rat nervous system

Mulder, J; Wernérus, H; Shi, T-J; Pontén, Fredrik et al.

Part of Neuroscience, p. 1689-1703, 2007

• DOI for Systematically generated antibodies against human gene products: High throughput screening on sections from the rat nervous system

From gene expression analysis to tissue microarrays: a rational approach to identify therapeutic and diagnostic targets in lymphoid malignancies.

Ek, Sara; Andréasson, Ulrika; Hober, Sophia; Kampf, Caroline et al.

Part of Mol Cell Proteomics, p. 1072-81, 2006

• DOI for From gene expression analysis to tissue microarrays: a rational approach to identify therapeutic and diagnostic targets in lymphoid malignancies.

Biobanking of fresh frozen tissue: RNA is stable in nonfixed surgical specimens.

Micke, Patrick; Ohshima, Mitsuhiro; Tahmasebpoor, Simin; Ren, Zhi-Ping et al.

Part of Lab Invest, p. 202-11, 2006

Analysis of protein expression in cell microarrays: A tool for antibody-based proteomics

Andersson, Ann-Catrin; Strömberg, Sara; Bäckvall, Helena; Kampf, Caroline et al.

Part of Journal of Histochemistry and Cytochemistry, p. 1413-1423, 2006

• DOI for Analysis of protein expression in cell microarrays: A tool for antibody-based proteomics

Effect of herbal melanin on IL-8: a possible role of Toll-like receptor 4 (TLR4).

El-Obeid, Adila; Hassib, Adil; Pontén, Fredrik; Westermark, Bengt

Part of Biochem Biophys Res Commun, p. 1200-6, 2006

Towards a human proteome atlas: high-throughput generation of mono-specific antibodies for tissue profiling

Nilsson, Peter; Paavilainen, Linda; Larsson, Karin; Ödling, Jenny et al.

Part of Proteomics, p. 4327-4337, 2005

• DOI for Towards a human proteome atlas: high-throughput generation of mono-specific antibodies for tissue profiling

A human protein atlas for normal and cancer tissues based on antibody proteomics

Uhlen, Mathias; Bjorling, Erik; Agaton, Charlotta; Szigyarto, Cristina Al-Khalili et al.

Part of Molecular & Cellular Proteomics, p. 1920-1932, 2005

• DOI for A human protein atlas for normal and cancer tissues based on antibody proteomics

Laser-assisted cell microdissection using the PALM system.

Micke, Patrick; Östman, Arne; Lundeberg, Joakim; Ponten, Fredrik

Part of Methods Mol Biol, p. 151-66, 2005

Binding sites for metabolic disease related transcription factors inferred at base pair resolution by chromatin immunoprecipitation and genomic microarrays

Rada-Iglesias, Alvaro; Wallerman, Ola; Koch, Christoph; Ameur, Adam et al.

Part of Human Molecular Genetics, p. 3435-3447, 2005

• DOI for Binding sites for metabolic disease related transcription factors inferred at base pair resolution by chromatin immunoprecipitation and genomic microarrays

Genetic tumor archeology: microdissection and genetic heterogeneity in squamous and basal cell carcinoma.

Bäckvall, Helena; Asplund, Anna; Gustafsson, Anna; Sivertsson, Asa et al.

Part of Mutat Res, p. 65-79, 2005

Antibody-based proteomics for human tissue profiling.

Uhlen, Mathias; Ponten, Fredrik

Part of Mol Cell Proteomics, p. 384-93, 2005

A fluid cover medium provides superior morphology and preserves RNA integrity in tissue sections for laser microdissection and pressure catapulting

Micke, Patrick; Bjørnsen, Tone; Scheidl, Stefan; Strömberg, Sara et al.

Part of J Pathol, p. 130-8, 2004

The role of p53 codon 72 and human papilloma virus status of cutaneous squamous cell carcinoma in the Swedish population.

Gustafsson, Anna C; Ren, Zhi-Ping; Asplund, Anna; Pontén, Fredrik et al.

Part of Acta Derm Venereol, p. 439-44, 2004

Antibody-based tissue profiling as a tool for clinical proteomics

Kampf, Caroline; Andersson, Ann-Catrin; Wester, Kenneth; Björling, Erik et al.

Part of Clinical Proteomics, p. 285-299, 2004

Zinc-based fixative improves preservation of genomic DNA and proteins in histoprocessing of human tissues.

Wester, Kenneth; Asplund, Anna; Bäckvall, Helena; Micke, Patrick et al.

Part of Lab Invest, p. 889-99, 2003

Enhanced epidermal ultraviolet responses in chronically sun-exposed skinare dependent on previous sun exposure.

Wassberg, C; Backvall, H; Diffey, B; Ponten, F et al.

Part of Acta Derm Venereol, p. 254, 2003

Similar UV responses are seen in a skin organ culture as in human skin in vivo

Bäckvall, Helena; Wassberg, Cecilia; Berne, Berit; Pontén, Fredrik

Part of Experimental dermatology, p. 349-356, 2002

• DOI for Similar UV responses are seen in a skin organ culture as in human skin in vivo

Rapid increase in diagnosis of cutaneous melanoma in situ in Sweden 1968-1992

Thörn, Magnus; Pontén, Fredrik; Johansson, Anna-Maria; Bergström, Reinhold

Part of Cancer Detect Prev, p. 430-437, 1998

Reconstruction of the two-dimensional distribution of p53 positive staining patches in sun-exposed morphologically normal skin

Ren, Z-P; Pontén, F; Nistér, M; Pontén, J

Part of Int J Oncol, p. 111-115, 1997

Elevated levels of the human endogenous retrovirus ERV3 in human sebaceous glands

Andersson, Ann-Catrin; Merza, Malik; Venables, Patrick JW; Pontén, Fredrik et al.

Part of Journal of Investigative Dermatology, p. 125-128, 1996

• DOI for Elevated levels of the human endogenous retrovirus ERV3 in human sebaceous glands

Two distinct p53 immunohistochemical patterns in human squamous-cell skin cancer, precursors and normal epidermis

Ren, Z-P; Pontén, F; Nistér, M; Pontén, J

Part of Int J Cancer, p. 174-179, 1996

Transcriptomics resources of human tissues and organs

Uhlen, Mathias; Hallstrom, Bjorn M.; Lindskog Bergström, Cecilia; Mardinoglu, Adil et al.

Part of Molecular Systems Biology, 2016

• DOI for Transcriptomics resources of human tissues and organs
• Download full text (pdf) of Transcriptomics resources of human tissues and organs

Garbage in, garbage out: A critical evaluation of strategies used for validation of immunohistochemical biomarkers

O'Hurley, Gillian; Sjöstedt, Evelina; Rahman, Arman; Li, Bo et al.

Part of Molecular Oncology, p. 783-798, 2014

• DOI for Garbage in, garbage out: A critical evaluation of strategies used for validation of immunohistochemical biomarkers

Heart Research Advances Using Database Search Engines, Human Protein Atlas and the Sydney Heart Bank

Li, Amy; Estigoy, Colleen; Raftery, Mark; Cameron, Darryl et al.

Part of Heart, Lung and Circulation, p. 819-826, 2013

• DOI for Heart Research Advances Using Database Search Engines, Human Protein Atlas and the Sydney Heart Bank

The interactome of LIM domain proteins: The contributions of LIM domain proteins to heart failure and heart development

Li, Amy; Pontén, Fredrik; dos Remedios, Cristobal G.

Part of Proteomics, p. 203-225, 2012

• DOI for The interactome of LIM domain proteins: The contributions of LIM domain proteins to heart failure and heart development

Antibodies for profiling the human proteome: The Human Protein Atlas as a resource for cancer research

Asplund, Anna; Edqvist, Per-Henrik D; Schwenk, Jochen M; Pontén, Fredrik

Part of Proteomics, p. 2067-2077, 2012

• DOI for Antibodies for profiling the human proteome: The Human Protein Atlas as a resource for cancer research

The Human Protein Atlas as a proteomic resource for biomarker discovery

Pontén, Fredrik; Schwenk, J. M.; Asplund, Anna; Edqvist, Per-Henrik D.

Part of Journal of Internal Medicine, p. 428-446, 2011

• DOI for The Human Protein Atlas as a proteomic resource for biomarker discovery

Antibody-based proteomics: fast-tracking molecular diagnostics in oncology

Brennan, Donal J.; O'Connor, Darran P.; Rexhepaj, Elton; Pontén, Fredrik et al.

Part of Nature Reviews. Cancer, p. 605-617, 2010

• DOI for Antibody-based proteomics: fast-tracking molecular diagnostics in oncology

Profiling protein expression and interactions: proximity ligation as a tool for personalized medicine

Blokzijl, Andries; Friedman, Mikaela; Pontén, Fredrik; Landegren, Ulf

Part of Journal of Internal Medicine, p. 232-245, 2010

• DOI for Profiling protein expression and interactions: proximity ligation as a tool for personalized medicine

Approaching clinical proteomics: current state and future fields of application in fluid proteomics

Apweiler, Rolf; Aslanidis, Charalampos; Deufel, Thomas; Gerstner, Andreas et al.

Part of Clinical Chemistry and Laboratory Medicine, p. 724-744, 2009

• DOI for Approaching clinical proteomics: current state and future fields of application in fluid proteomics

Approaching clinical proteomics: current state and future fields of application in cellular proteomics

Apweiler, Rolf; Aslanidis, Charalampos; Deufel, Thomas; Gerstner, Andreas et al.

Part of Cytometry. Part A : the journal of the International Society for Analytical Cytology, p. 816-832, 2009

• DOI for Approaching clinical proteomics: current state and future fields of application in cellular proteomics

A genecentric Human Protein Atlas for expression profiles based on antibodies

Berglund, Lisa; Björling, Erik; Oksvold, Per; Fagerberg, Linn et al.

Part of Molecular & Cellular Proteomics, p. 2019-2027, 2008

• DOI for A genecentric Human Protein Atlas for expression profiles based on antibodies

Antibody Validation for Estrogen Receptor Beta

Birgersson, Madeleine; Katona, Borbala; Lindskog, Cecilia; Pontén, Fredrik et al.

Part of Estrogen Receptors. Methods in Molecular Biology, p. 1-23, Springer Nature, 2022

• DOI for Antibody Validation for Estrogen Receptor Beta

Expression of podocalyxin-like protein and epidermal growth factor receptor in metastatic colorectal cancer: Prognostic impact and relationship with response to cetuximab.

Larsson, Anna; Karnevi, Emelie; Nodin, Bjorn; Sorbye, Halfdan et al.

2018

• DOI for Expression of podocalyxin-like protein and epidermal growth factor receptor in metastatic colorectal cancer: Prognostic impact and relationship with response to cetuximab.

Prognostic significance of SATB1 expression in metastatic colorectal cancer: A Nordic prospective cohort study.

Siesing, Christina; Sorbye, Halfdan; Dragomir, Anca; Pfeiffer, Per et al.

Part of ASCO 2018 Gastrointestinal Cancers Symposium, p. 707-707, 2018

• DOI for Prognostic significance of SATB1 expression in metastatic colorectal cancer: A Nordic prospective cohort study.

Automated Analysis of Human Protein Atlas Immunofluorescence Images

Newberg, Justin Y; Li, Jieyue; Rao, Arvind; Pontén, Fredrik et al.

Part of 2009 IEEE International Symposium on Biomedical Imaging, p. 1023-1026, 2009

• DOI for Automated Analysis of Human Protein Atlas Immunofluorescence Images

Extending the immune phenotypes of lung cancer: Oasis in the desert

Backman, Max; La Fleur, Linnea; Kurppa, Pinja; Djureinovic, Dijana et al.

Angiogenesis as a risk factor for young women with breast cancer

Magnusson, Kristina; Fredholm, Hanna; Georganaki, Maria; Uhlén, Mathias et al.