Anders Isaksson
Senior research engineer at Department of Immunology, Genetics and Pathology; Research programme: Cancer Precision Medicine; Research group Tobias Sjöblom
- E-mail:
- anders.isaksson@igp.uu.se
- Visiting address:
- Dag Hammarskjölds väg 20
751 37 Uppsala - Postal address:
- Rudbecklaboratoriet
751 85 Uppsala
Keywords
- machine learning
- digital pathology
- algorithm development
- cytology and ai and deep learning
- artificiell intelligens
- maskininlärning
- ai
- dna microarrays
- cancer genomics
- artificial intelligens
- dna copy number analysis
Publications
Recent publications
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Part of ESMO Gastrointestinal Oncology, 2025
- DOI for Molecular classification of microsatellite-instable colorectal cancers reveals distinct predictors of immunotherapy response
- Download full text (pdf) of Molecular classification of microsatellite-instable colorectal cancers reveals distinct predictors of immunotherapy response
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Tissue-resident microbiota impacts colorectal cancer progression and prognosis
Part of Nature Communications, 2025
- DOI for Tissue-resident microbiota impacts colorectal cancer progression and prognosis
- Download full text (pdf) of Tissue-resident microbiota impacts colorectal cancer progression and prognosis
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Part of JACC: Basic to Translational Science, 2025
- DOI for Plasma-Derived Extracellular Vesicle-Propagated microRNA From Aortic Stenosis Patients Render Pro-Calcifying Effects on Valve Interstitial Cells
- Download full text (pdf) of Plasma-Derived Extracellular Vesicle-Propagated microRNA From Aortic Stenosis Patients Render Pro-Calcifying Effects on Valve Interstitial Cells
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Part of Gut, 2025
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Part of International Journal of Molecular Sciences, 2022
- DOI for MircoRNA in Extracellular Vesicles from Patients with Pulmonary Arterial Hypertension Alters Endothelial Angiogenic Response
- Download full text (pdf) of MircoRNA in Extracellular Vesicles from Patients with Pulmonary Arterial Hypertension Alters Endothelial Angiogenic Response
All publications
Articles in journal
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Part of ESMO Gastrointestinal Oncology, 2025
- DOI for Molecular classification of microsatellite-instable colorectal cancers reveals distinct predictors of immunotherapy response
- Download full text (pdf) of Molecular classification of microsatellite-instable colorectal cancers reveals distinct predictors of immunotherapy response
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Tissue-resident microbiota impacts colorectal cancer progression and prognosis
Part of Nature Communications, 2025
- DOI for Tissue-resident microbiota impacts colorectal cancer progression and prognosis
- Download full text (pdf) of Tissue-resident microbiota impacts colorectal cancer progression and prognosis
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Part of JACC: Basic to Translational Science, 2025
- DOI for Plasma-Derived Extracellular Vesicle-Propagated microRNA From Aortic Stenosis Patients Render Pro-Calcifying Effects on Valve Interstitial Cells
- Download full text (pdf) of Plasma-Derived Extracellular Vesicle-Propagated microRNA From Aortic Stenosis Patients Render Pro-Calcifying Effects on Valve Interstitial Cells
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Part of Gut, 2025
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Part of International Journal of Molecular Sciences, 2022
- DOI for MircoRNA in Extracellular Vesicles from Patients with Pulmonary Arterial Hypertension Alters Endothelial Angiogenic Response
- Download full text (pdf) of MircoRNA in Extracellular Vesicles from Patients with Pulmonary Arterial Hypertension Alters Endothelial Angiogenic Response
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Part of npj Precision Oncology, 2021
- DOI for FOXP3+ T cells in uterine sarcomas are associated with favorable prognosis, low extracellular matrix expression and reduced YAP activation
- Download full text (pdf) of FOXP3+ T cells in uterine sarcomas are associated with favorable prognosis, low extracellular matrix expression and reduced YAP activation
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Part of Cancer Genetics, p. 34-41, 2020
- DOI for Genomic and transcriptomic features of dermatofibrosarcoma protuberans: Unusual chromosomal origin of the COL1A1-PDGFB fusion gene and synergistic effects of amplified regions in tumor development
- Download full text (pdf) of Genomic and transcriptomic features of dermatofibrosarcoma protuberans: Unusual chromosomal origin of the COL1A1-PDGFB fusion gene and synergistic effects of amplified regions in tumor development
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Inter- and intra-breed genome-wide copy number diversity in a large cohort of European equine breeds
Part of BMC Genomics, 2019
- DOI for Inter- and intra-breed genome-wide copy number diversity in a large cohort of European equine breeds
- Download full text (pdf) of Inter- and intra-breed genome-wide copy number diversity in a large cohort of European equine breeds
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Part of Annals of Surgical Oncology, p. 4835-4842, 2019
- DOI for Gains of Chromosome 1p and 15q are Associated with Poor Survival After Cytoreductive Surgery and HIPEC for Treating Colorectal Peritoneal Metastases
- Download full text (pdf) of Gains of Chromosome 1p and 15q are Associated with Poor Survival After Cytoreductive Surgery and HIPEC for Treating Colorectal Peritoneal Metastases
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Part of Clinical Cancer Research, p. 2155-2165, 2019
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Four evolutionary trajectories underlie genetic intratumoral variation in childhood cancer
Part of Nature Genetics, p. 944-950, 2018
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Different patterns of clonal evolution among different sarcoma subtypes followed for up to 25 years
Part of Nature Communications, 2018
- DOI for Different patterns of clonal evolution among different sarcoma subtypes followed for up to 25 years
- Download full text (pdf) of Different patterns of clonal evolution among different sarcoma subtypes followed for up to 25 years
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Part of Leukemia, p. 2117-2125, 2018
- DOI for Mutation, methylation, and gene expression profiles in dup(1q)-positive pediatric B-cell precursor acute lymphoblastic leukemia
- Download full text (pdf) of Mutation, methylation, and gene expression profiles in dup(1q)-positive pediatric B-cell precursor acute lymphoblastic leukemia
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Part of Neuro-Oncology, p. 1080-1091, 2018
- DOI for Primary glioblastoma cells for precision medicine: a quantitative portrait of genomic (in)stability during the first 30 passages
- Download full text (pdf) of Primary glioblastoma cells for precision medicine: a quantitative portrait of genomic (in)stability during the first 30 passages
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Part of Stem Cell Reports, p. 1449-1461, 2018
- DOI for Increased Calcium Influx through L-type Calcium Channels in Human and Mouse Neural Progenitors Lacking Fragile X Mental Retardation Protein
- Download full text (pdf) of Increased Calcium Influx through L-type Calcium Channels in Human and Mouse Neural Progenitors Lacking Fragile X Mental Retardation Protein
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Scattered genomic amplification in dedifferentiated liposarcoma
Part of Molecular Cytogenetics, 2017
- DOI for Scattered genomic amplification in dedifferentiated liposarcoma
- Download full text (pdf) of Scattered genomic amplification in dedifferentiated liposarcoma
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Somatic Ephrin Receptor Mutations Are Associated with Metastasis in Primary Colorectal Cancer
Part of Cancer Research, p. 1730-1740, 2017
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Part of Haematologica, p. 68-68, 2017
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Part of Molecular Medicine Reports, p. 1513-1526, 2017
- DOI for Gene expression profiles in preterm infants on continuous long-term oxygen therapy suggest reduced oxidative stress-dependent signaling during hypoxia
- Download full text (pdf) of Gene expression profiles in preterm infants on continuous long-term oxygen therapy suggest reduced oxidative stress-dependent signaling during hypoxia
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Rawcopy: Improved copy number analysis with Affymetrix arrays
Part of Scientific Reports, 2016
- DOI for Rawcopy: Improved copy number analysis with Affymetrix arrays
- Download full text (pdf) of Rawcopy: Improved copy number analysis with Affymetrix arrays
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Intratumoral genome diversity parallels progression and predicts outcome in pediatric cancer
Part of Nature Communications, 2015
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Part of BMC Cancer, 2015
- DOI for Microsatellite instability and mutations in BRAF and KRAS are significant predictors of disseminated disease in colon cancer
- Download full text (pdf) of Microsatellite instability and mutations in BRAF and KRAS are significant predictors of disseminated disease in colon cancer
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Part of Clinical Cancer Research, p. 4451-4460, 2015
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Part of Cancer Discovery, p. 488-505, 2015
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Part of BMC Cancer, p. 872, 2014
- DOI for 1p36 deletion is a marker for tumour dissemination in microsatellite stable stage II-III colon cancer
- Download full text (pdf) of 1p36 deletion is a marker for tumour dissemination in microsatellite stable stage II-III colon cancer
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Part of Leukemia, p. 150-158, 2013
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Part of Cancer Chemotherapy and Pharmacology, p. 329-340, 2013
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Part of PLOS ONE, 2013
- DOI for Behavioural and Brain Gene Expression Profiling in Pigs during Tail Biting Outbreaks - Evidence of a Tail Biting Resistant Phenotype
- Download full text (pdf) of Behavioural and Brain Gene Expression Profiling in Pigs during Tail Biting Outbreaks - Evidence of a Tail Biting Resistant Phenotype
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Patchwork: allele-specific copy number analysis of whole-genome sequenced tumor tissue
Part of Genome Biology, 2013
- DOI for Patchwork: allele-specific copy number analysis of whole-genome sequenced tumor tissue
- Download full text (pdf) of Patchwork: allele-specific copy number analysis of whole-genome sequenced tumor tissue
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Brain gene expression differences are associated with abnormal tail biting behavior in pigs
Part of Genes, Brain and Behavior, p. 275-281, 2013
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Part of BMC Cancer, p. 407, 2012
- DOI for Loss-of-heterozygosity on chromosome 19q in early-stage serous ovarian cancer is associated with recurrent disease
- Download full text (pdf) of Loss-of-heterozygosity on chromosome 19q in early-stage serous ovarian cancer is associated with recurrent disease
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Part of American Journal of Hematology, p. 361-367, 2012
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Part of European Journal of Cancer, 2012
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Part of Clinical Cancer Research, p. 2695-2703, 2012
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Part of Epigenetics : official journal of the DNA Methylation Society, p. 1435-1442, 2012
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The transcriptome of the adenovirus infected cell
Part of Virology, p. 115-128, 2012
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Next generation RNA-sequencing in prognostic subsets of chronic lymphocytic leukemia
Part of American Journal of Hematology, p. 737-740, 2012
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Allele-specific copy number analysis of tumor samples with aneuploidy and tumor heterogeneity
Part of Genome Biology, 2011
- DOI for Allele-specific copy number analysis of tumor samples with aneuploidy and tumor heterogeneity
- Download full text (pdf) of Allele-specific copy number analysis of tumor samples with aneuploidy and tumor heterogeneity
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Prostasomal DNA Characterization and Transfer Into Human Sperm
Part of Molecular Reproduction and Development, p. 467-476, 2011
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Array-based genomic screening at diagnosis and during follow-up in chronic lymphocytic leukemia
Part of Haematologica, p. 1161-1169, 2011
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Part of Genes, Chromosomes and Cancer, p. 113-121, 2011
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Part of Journal of Thoracic Oncology, p. 1833-1840, 2011
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Part of Poultry Science, p. 1145-1152, 2011
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Part of Blood, p. 296-305, 2010
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Part of Haematologica, p. 2072-2079, 2010
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Part of Haematologica, p. 1519-1525, 2010
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Part of Anti-Cancer Drugs, p. 33-42, 2010
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Part of Artificial Intelligence in Medicine, p. 93-104, 2010
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Characterization of the RNA content of chromatin
Part of Genome Research, p. 899-907, 2010
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Part of Leukemia, p. 211-215, 2010
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Stathmin as a Marker for Malignancy in Pheochromocytomas
Part of Experimental and clinical endocrinology & diabetes, p. 27-30, 2010
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Part of Investigational new drugs, p. 402-411, 2009
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Extensive expression of craniofacial related homeobox genes in canine mammary sarcomas
Part of Breast Cancer Research and Treatment, p. 333-343, 2009
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Part of PloS one, 2009
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Cross-validation and bootstrapping are unreliable in small sample classification
Part of Pattern Recognition Letters, p. 1960-1965, 2008
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Part of Gene Therapy and Molecular Biology, p. 359-370, 2008
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Part of Genome biology, 2008
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Part of Genes, Chromosomes and Cancer, p. 697-711, 2008
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Part of Leukemia Research, p. 931-938, 2007
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Part of BMC Systems Biology, p. 45, 2007
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Part of Nucleic Acids Research, 2007
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Part of International Journal of Cancer, p. 189-195, 2007
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Part of Biochemical Pharmacology, p. 25-33, 2007
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In vitro drug sensitivity-gene expression correlations involve a tissue of origin dependency
Part of Journal of chemical information and modeling, p. 239-248, 2007
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Bayesian detection of periodic mRNA time profiles withouth use of training examples
Part of BMC Bioinformatics, p. 63, 2006
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Part of BMC Bioinformatics, p. 127, 2006
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Characterization of an imatinib-sensitive subset of high-grade human glioma cultures
Part of Oncogene, p. 4913-4922, 2006
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Screening of an annotated compound library for drug activity in a resistant myeloma cell line
Part of Cancer Chemotherapy and Pharmacology, p. 749-758, 2006
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Constitutional downregulation of SEMA5A expression in autism
Part of Neuropsychobiology, p. 64-69, 2006
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Part of Journal of Biomolecular Screening, p. 457-468, 2006
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Molecular markers for discrimination of benign and malignant follicular thyroid tumors
Part of Tumor Biology, p. 211-220, 2006
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Part of Proteins, p. 918-925, 2005
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Part of British Journal of Cancer, p. 483-492, 2005