Anders Isaksson
1:e Forskningsing vid Institutionen för immunologi, genetik och patologi; Forskningsprogram: Cancerprecisionsmedicin; Forskargrupp Tobias Sjöblom
- E-post:
- anders.isaksson@igp.uu.se
- Besöksadress:
- Dag Hammarskjölds väg 20
751 37 Uppsala - Postadress:
- Rudbecklaboratoriet
751 85 Uppsala
- Akademiska meriter:
- docent
Nyckelord
- machine learning
- digital pathology
- algorithm development
- cytology and ai and deep learning
- artificiell intelligens
- maskininlärning
- ai
- dna microarrays
- cancer genomics
- artificial intelligens
- dna copy number analysis
Publikationer
Senaste publikationer
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Ingår i ESMO Gastrointestinal Oncology, 2025
- DOI för Molecular classification of microsatellite-instable colorectal cancers reveals distinct predictors of immunotherapy response
- Ladda ner fulltext (pdf) av Molecular classification of microsatellite-instable colorectal cancers reveals distinct predictors of immunotherapy response
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Tissue-resident microbiota impacts colorectal cancer progression and prognosis
Ingår i Nature Communications, 2025
- DOI för Tissue-resident microbiota impacts colorectal cancer progression and prognosis
- Ladda ner fulltext (pdf) av Tissue-resident microbiota impacts colorectal cancer progression and prognosis
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Ingår i JACC: Basic to Translational Science, 2025
- DOI för Plasma-Derived Extracellular Vesicle-Propagated microRNA From Aortic Stenosis Patients Render Pro-Calcifying Effects on Valve Interstitial Cells
- Ladda ner fulltext (pdf) av Plasma-Derived Extracellular Vesicle-Propagated microRNA From Aortic Stenosis Patients Render Pro-Calcifying Effects on Valve Interstitial Cells
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Ingår i Gut, 2025
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Ingår i International Journal of Molecular Sciences, 2022
- DOI för MircoRNA in Extracellular Vesicles from Patients with Pulmonary Arterial Hypertension Alters Endothelial Angiogenic Response
- Ladda ner fulltext (pdf) av MircoRNA in Extracellular Vesicles from Patients with Pulmonary Arterial Hypertension Alters Endothelial Angiogenic Response
Alla publikationer
Artiklar i tidskrift
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Ingår i ESMO Gastrointestinal Oncology, 2025
- DOI för Molecular classification of microsatellite-instable colorectal cancers reveals distinct predictors of immunotherapy response
- Ladda ner fulltext (pdf) av Molecular classification of microsatellite-instable colorectal cancers reveals distinct predictors of immunotherapy response
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Tissue-resident microbiota impacts colorectal cancer progression and prognosis
Ingår i Nature Communications, 2025
- DOI för Tissue-resident microbiota impacts colorectal cancer progression and prognosis
- Ladda ner fulltext (pdf) av Tissue-resident microbiota impacts colorectal cancer progression and prognosis
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Ingår i JACC: Basic to Translational Science, 2025
- DOI för Plasma-Derived Extracellular Vesicle-Propagated microRNA From Aortic Stenosis Patients Render Pro-Calcifying Effects on Valve Interstitial Cells
- Ladda ner fulltext (pdf) av Plasma-Derived Extracellular Vesicle-Propagated microRNA From Aortic Stenosis Patients Render Pro-Calcifying Effects on Valve Interstitial Cells
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Ingår i Gut, 2025
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Ingår i International Journal of Molecular Sciences, 2022
- DOI för MircoRNA in Extracellular Vesicles from Patients with Pulmonary Arterial Hypertension Alters Endothelial Angiogenic Response
- Ladda ner fulltext (pdf) av MircoRNA in Extracellular Vesicles from Patients with Pulmonary Arterial Hypertension Alters Endothelial Angiogenic Response
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Ingår i npj Precision Oncology, 2021
- DOI för FOXP3+ T cells in uterine sarcomas are associated with favorable prognosis, low extracellular matrix expression and reduced YAP activation
- Ladda ner fulltext (pdf) av FOXP3+ T cells in uterine sarcomas are associated with favorable prognosis, low extracellular matrix expression and reduced YAP activation
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Ingår i Cancer Genetics, s. 34-41, 2020
- DOI för Genomic and transcriptomic features of dermatofibrosarcoma protuberans: Unusual chromosomal origin of the COL1A1-PDGFB fusion gene and synergistic effects of amplified regions in tumor development
- Ladda ner fulltext (pdf) av Genomic and transcriptomic features of dermatofibrosarcoma protuberans: Unusual chromosomal origin of the COL1A1-PDGFB fusion gene and synergistic effects of amplified regions in tumor development
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Inter- and intra-breed genome-wide copy number diversity in a large cohort of European equine breeds
Ingår i BMC Genomics, 2019
- DOI för Inter- and intra-breed genome-wide copy number diversity in a large cohort of European equine breeds
- Ladda ner fulltext (pdf) av Inter- and intra-breed genome-wide copy number diversity in a large cohort of European equine breeds
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Ingår i Annals of Surgical Oncology, s. 4835-4842, 2019
- DOI för Gains of Chromosome 1p and 15q are Associated with Poor Survival After Cytoreductive Surgery and HIPEC for Treating Colorectal Peritoneal Metastases
- Ladda ner fulltext (pdf) av Gains of Chromosome 1p and 15q are Associated with Poor Survival After Cytoreductive Surgery and HIPEC for Treating Colorectal Peritoneal Metastases
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Ingår i Clinical Cancer Research, s. 2155-2165, 2019
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Four evolutionary trajectories underlie genetic intratumoral variation in childhood cancer
Ingår i Nature Genetics, s. 944-950, 2018
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Different patterns of clonal evolution among different sarcoma subtypes followed for up to 25 years
Ingår i Nature Communications, 2018
- DOI för Different patterns of clonal evolution among different sarcoma subtypes followed for up to 25 years
- Ladda ner fulltext (pdf) av Different patterns of clonal evolution among different sarcoma subtypes followed for up to 25 years
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Ingår i Leukemia, s. 2117-2125, 2018
- DOI för Mutation, methylation, and gene expression profiles in dup(1q)-positive pediatric B-cell precursor acute lymphoblastic leukemia
- Ladda ner fulltext (pdf) av Mutation, methylation, and gene expression profiles in dup(1q)-positive pediatric B-cell precursor acute lymphoblastic leukemia
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Ingår i Neuro-Oncology, s. 1080-1091, 2018
- DOI för Primary glioblastoma cells for precision medicine: a quantitative portrait of genomic (in)stability during the first 30 passages
- Ladda ner fulltext (pdf) av Primary glioblastoma cells for precision medicine: a quantitative portrait of genomic (in)stability during the first 30 passages
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Ingår i Stem Cell Reports, s. 1449-1461, 2018
- DOI för Increased Calcium Influx through L-type Calcium Channels in Human and Mouse Neural Progenitors Lacking Fragile X Mental Retardation Protein
- Ladda ner fulltext (pdf) av Increased Calcium Influx through L-type Calcium Channels in Human and Mouse Neural Progenitors Lacking Fragile X Mental Retardation Protein
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Scattered genomic amplification in dedifferentiated liposarcoma
Ingår i Molecular Cytogenetics, 2017
- DOI för Scattered genomic amplification in dedifferentiated liposarcoma
- Ladda ner fulltext (pdf) av Scattered genomic amplification in dedifferentiated liposarcoma
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Somatic Ephrin Receptor Mutations Are Associated with Metastasis in Primary Colorectal Cancer
Ingår i Cancer Research, s. 1730-1740, 2017
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Ingår i Haematologica, s. 68-68, 2017
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Ingår i Molecular Medicine Reports, s. 1513-1526, 2017
- DOI för Gene expression profiles in preterm infants on continuous long-term oxygen therapy suggest reduced oxidative stress-dependent signaling during hypoxia
- Ladda ner fulltext (pdf) av Gene expression profiles in preterm infants on continuous long-term oxygen therapy suggest reduced oxidative stress-dependent signaling during hypoxia
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Rawcopy: Improved copy number analysis with Affymetrix arrays
Ingår i Scientific Reports, 2016
- DOI för Rawcopy: Improved copy number analysis with Affymetrix arrays
- Ladda ner fulltext (pdf) av Rawcopy: Improved copy number analysis with Affymetrix arrays
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Intratumoral genome diversity parallels progression and predicts outcome in pediatric cancer
Ingår i Nature Communications, 2015
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Ingår i BMC Cancer, 2015
- DOI för Microsatellite instability and mutations in BRAF and KRAS are significant predictors of disseminated disease in colon cancer
- Ladda ner fulltext (pdf) av Microsatellite instability and mutations in BRAF and KRAS are significant predictors of disseminated disease in colon cancer
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Ingår i Clinical Cancer Research, s. 4451-4460, 2015
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Ingår i Cancer Discovery, s. 488-505, 2015
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Ingår i BMC Cancer, s. 872, 2014
- DOI för 1p36 deletion is a marker for tumour dissemination in microsatellite stable stage II-III colon cancer
- Ladda ner fulltext (pdf) av 1p36 deletion is a marker for tumour dissemination in microsatellite stable stage II-III colon cancer
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Ingår i Leukemia, s. 150-158, 2013
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Ingår i Cancer Chemotherapy and Pharmacology, s. 329-340, 2013
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Ingår i PLOS ONE, 2013
- DOI för Behavioural and Brain Gene Expression Profiling in Pigs during Tail Biting Outbreaks - Evidence of a Tail Biting Resistant Phenotype
- Ladda ner fulltext (pdf) av Behavioural and Brain Gene Expression Profiling in Pigs during Tail Biting Outbreaks - Evidence of a Tail Biting Resistant Phenotype
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Patchwork: allele-specific copy number analysis of whole-genome sequenced tumor tissue
Ingår i Genome Biology, 2013
- DOI för Patchwork: allele-specific copy number analysis of whole-genome sequenced tumor tissue
- Ladda ner fulltext (pdf) av Patchwork: allele-specific copy number analysis of whole-genome sequenced tumor tissue
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Brain gene expression differences are associated with abnormal tail biting behavior in pigs
Ingår i Genes, Brain and Behavior, s. 275-281, 2013
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Ingår i BMC Cancer, s. 407, 2012
- DOI för Loss-of-heterozygosity on chromosome 19q in early-stage serous ovarian cancer is associated with recurrent disease
- Ladda ner fulltext (pdf) av Loss-of-heterozygosity on chromosome 19q in early-stage serous ovarian cancer is associated with recurrent disease
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Ingår i American Journal of Hematology, s. 361-367, 2012
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Ingår i European Journal of Cancer, 2012
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Ingår i Clinical Cancer Research, s. 2695-2703, 2012
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Ingår i Epigenetics : official journal of the DNA Methylation Society, s. 1435-1442, 2012
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The transcriptome of the adenovirus infected cell
Ingår i Virology, s. 115-128, 2012
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Next generation RNA-sequencing in prognostic subsets of chronic lymphocytic leukemia
Ingår i American Journal of Hematology, s. 737-740, 2012
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Allele-specific copy number analysis of tumor samples with aneuploidy and tumor heterogeneity
Ingår i Genome Biology, 2011
- DOI för Allele-specific copy number analysis of tumor samples with aneuploidy and tumor heterogeneity
- Ladda ner fulltext (pdf) av Allele-specific copy number analysis of tumor samples with aneuploidy and tumor heterogeneity
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Prostasomal DNA Characterization and Transfer Into Human Sperm
Ingår i Molecular Reproduction and Development, s. 467-476, 2011
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Array-based genomic screening at diagnosis and during follow-up in chronic lymphocytic leukemia
Ingår i Haematologica, s. 1161-1169, 2011
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Ingår i Genes, Chromosomes and Cancer, s. 113-121, 2011
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Ingår i Journal of Thoracic Oncology, s. 1833-1840, 2011
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Ingår i Poultry Science, s. 1145-1152, 2011
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Ingår i Blood, s. 296-305, 2010
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Ingår i Haematologica, s. 2072-2079, 2010
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Ingår i Haematologica, s. 1519-1525, 2010
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Ingår i Anti-Cancer Drugs, s. 33-42, 2010
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Ingår i Artificial Intelligence in Medicine, s. 93-104, 2010
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Characterization of the RNA content of chromatin
Ingår i Genome Research, s. 899-907, 2010
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Ingår i Leukemia, s. 211-215, 2010
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Stathmin as a Marker for Malignancy in Pheochromocytomas
Ingår i Experimental and clinical endocrinology & diabetes, s. 27-30, 2010
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Ingår i Investigational new drugs, s. 402-411, 2009
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Extensive expression of craniofacial related homeobox genes in canine mammary sarcomas
Ingår i Breast Cancer Research and Treatment, s. 333-343, 2009
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Ingår i PloS one, 2009
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Cross-validation and bootstrapping are unreliable in small sample classification
Ingår i Pattern Recognition Letters, s. 1960-1965, 2008
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Ingår i Gene Therapy and Molecular Biology, s. 359-370, 2008
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Ingår i Genome biology, 2008
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Ingår i Genes, Chromosomes and Cancer, s. 697-711, 2008
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Ingår i Leukemia Research, s. 931-938, 2007
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Ingår i BMC Systems Biology, s. 45, 2007
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Ingår i Nucleic Acids Research, 2007
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Ingår i International Journal of Cancer, s. 189-195, 2007
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Ingår i Biochemical Pharmacology, s. 25-33, 2007
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In vitro drug sensitivity-gene expression correlations involve a tissue of origin dependency
Ingår i Journal of chemical information and modeling, s. 239-248, 2007
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Bayesian detection of periodic mRNA time profiles withouth use of training examples
Ingår i BMC Bioinformatics, s. 63, 2006
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Ingår i BMC Bioinformatics, s. 127, 2006
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Characterization of an imatinib-sensitive subset of high-grade human glioma cultures
Ingår i Oncogene, s. 4913-4922, 2006
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Screening of an annotated compound library for drug activity in a resistant myeloma cell line
Ingår i Cancer Chemotherapy and Pharmacology, s. 749-758, 2006
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Constitutional downregulation of SEMA5A expression in autism
Ingår i Neuropsychobiology, s. 64-69, 2006
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Ingår i Journal of Biomolecular Screening, s. 457-468, 2006
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Molecular markers for discrimination of benign and malignant follicular thyroid tumors
Ingår i Tumor Biology, s. 211-220, 2006
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Ingår i Proteins, s. 918-925, 2005
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Ingår i British Journal of Cancer, s. 483-492, 2005