Computational and Systems Biology II

15 credits

Syllabus, Master's level, 1MB522

A revised version of the syllabus is available.
Code
1MB522
Education cycle
Second cycle
Main field(s) of study and in-depth level
Molecular Biotechnology A1F, Technology A1F
Grading system
Pass with distinction (5), Pass with credit (4), Pass (3), Fail (U)
Finalised by
The Faculty Board of Science and Technology, 7 March 2011
Responsible department
Biology Education Centre

Entry requirements

Computational and Systems Biology I

Learning outcomes

The aim of the course is to generate knowledge for usage, development and analysis of quantitative models of biological systems at both a molecular and cellular level. After passing the course, the student should be able to

  • Explain by quantitative measures the physical base for biomolecule structure
  • Write computer programmes for simulation of intracellular chemical processes
  • Determine the structure of a peptide from NMR experimental data
  • Make computer simulations for small biomolecules such as RNA and peptides
  • On an advanced level present the different factors that contribute to interactions between biomolecules
  • On an advanced level describe the content of relevant scientific literature

Content

Computer exercises on peptide structure determination based on NMR data, folding of RNA using different time and length scales, binding and folding of ligands and simulation of peptide folding. . Literature project.

Instruction

Lectures, seminars and computer exercises.

Assessment

Computer exercise 9 credits. Literature project 3 credits. Oral and written presentation (in English) of the literature project 3 credits Seminars 3 credits Participation in at least 80% of the seminars.