Genome Biology
Syllabus, Master's level, 1MB428
This course has been discontinued.
- Code
- 1MB428
- Education cycle
- Second cycle
- Main field(s) of study and in-depth level
- Bioinformatics A1N, Molecular Biotechnology A1N, Technology A1N
- Grading system
- Pass with distinction (5), Pass with credit (4), Pass (3), Fail (U)
- Finalised by
- The Faculty Board of Science and Technology, 28 April 2011
- Responsible department
- Biology Education Centre
Entry requirements
120 credits inclusive Genomics experimental methods and Methods in bioinformatics, or equivalent.
Learning outcomes
The course treats genome organisation, variation, evolution and function in different groups of organisms.
After the course, the student shall be able to
- Describe the genome architecture in selected organism groups
- Explain how different reproductive systems affect genome
- size and composition
- Sketchan explanatory model for the difference (in architecture and gene content) between genomes
- Explainhow genetic and transcriptional networks are regulated (on different levels)
- Discuss the practical consequences of the genome's biologyon bioinformatics applications
Content
Genome organisation, variation and expression
Genome content and architecture in different organismgroups, variation in the genome and its significance for the organism, mechanisms controlling gene expression.
Genome evolution
Forces and mechanisms controlling the genome's architecture; gene and genome duplications, organelles and plasmids, proliferation of repetitive and selfish elements, horizontal gene transfer. Comparative genomics, sexual reproduction and other recombination processes, sex and sex determination.
Genome function
Genetic and transcriptional networks, their regulation, epigenetics. Interactions between metabolic networks in natural settings; symbiosis and metagenomics.
Instruction
Instruction will be given as lectures, seminars and computer assignments.
Assessment
The theory part of the course is examined by a written theoretical examination and participation in seminars, equivalent to a total of 3 credits. Active participation in at least 80% of the seminars is required to pass. To pass the practical part, it is required that all computer exercises equivalent to 2 credits has been presented in writing and is passed.