Entry requirements

120 credits with 60 credits in chemistry.

Learning outcomes

The successful participant of this course will have the ability to:

• Present and discuss advanced methods in organic synthesis
• Find relevant information from the literature by database searching
• Apply various synthesis tools to organic compounds with low molecular weight.
• Describe and plan DOS (diversity-oriented synthesis)
• Present, discuss, plan and execute the construction and evaluation of a low-molecular-weight compound library.

Content

Tools for synthesis planning, such as retrosynthesis, DOS and high-throughput strategies and their application in organic synthesis. Reactivity and selectivity in organic-chemical transformations, and their importance in synthesis planning.

Individual design project, which includes the planning of the synthesis, literature search, a presentation, as well as experimental work to prepare the suggested molecules.

Training in communication skills with written report, oral presentation, feed-back and opposition.

Instruction

The teaching will be conducted by lectures, and practical work in the laboratory and theoretical exercises and projects. A significant part of the course takes place in the form of projects, where students work both individually and in groups.

Assessment

A written exam will be given in the end of the course (10 credits). Reports are assessed by written and oral presentation with opposition. The mandatory exercises and reports correspond to 5 credits. The final grade is based on both the written exam and the mandatory exercises.