General provisions

Correspond earlier course 3FK002 General Pharmaceutical Chemistry. 1.5 credits (hp) correspond to 1 credit point (p) according to earlier study regulation.

Content

In the section chemical binding, elementary quantum mechanics as a basis for atomic structure and covalent binding are treated. Further, the structure of the atom and properties are described, intra - and intermolecular interaction and the connection to physico-chemical properties and molecular geometries of the chemical binding. Molecular orbital theory is used to explain the concept of aromaticity. Zero, first and the kinetics of the other order be gone through. Within thermodynamics, the energy conservation theorem (the 1st main clause), the concepts of internal energy, enthalpy, thermal capacity, entropy (the 2nd main clause) and the free energy of the Gibb's, spontaneous processes and the connection are treated to the equilibrium constant and its temperature dependence. Further, chemical equilibria are treated (acid/base and solubility equilibria), and connected equilibria and the equilibria importance for the fate of drug in the body (dissolution, absorption and transport).

Instruction

The teaching is given as lectures, group work, seminars, demonstrations and laboratory sessions. The results of laboratory exercises are presented orally and in writing. Special importance is paid to stimulate the students to independently search information and solve problems.

Compulsory parts of the course:

all parts in connection with laboratory sessions.

Assessment

Examination is organised during the course and at the end of the course. Possibility to supplement failed laboratory course can be given at the earliest at next course and only in case of a vacancy. For passed in the course passed laboratory course (examination code) and passed examination (examination code) are required.