General provisions

Substitutes the earlier course 3FK003 Analytical Pharmaceutical Chemistry. 1.5 credit correspond to 1 credit according to earlier ordinance.

Entry requirements

For students within the pharmacy programme: gone through all earlier courses within the programme. For students on single subject course: General Pharmaceutical Chemistry 7.5 credits or equivalent.

Learning outcomes

On completion of the course, the student will be able to

- give examples of typical issues of analytical chemical nature at development and control of pharmaceuticals

- describe the electrochemical cell and account for its usage for pH determination

- the principle for the titrimetric quantitative analysis of pharmaceutical substances

- calculate conditions for distribution and separation of drug molecules with liquid-liquid extraction

- the basic principles for the UV-Vis absorption spectroscopy, fluorometry, atomic absorption and atomic emission and account for carrying out quantitative and qualitative analyses within the pharmaceutical field

- the basic principles for liquid chromatography, thin layer chromatography and gas chromatography

- account for quantitative analysis of drug molecules with chromatographic technologies

- account for the aim of validation of an analytical method and define the most common concepts that are included in the validation

- be familiar with basic experimental methodology in the area of drug analysis

Content

The course is mainly aimed at principles for quantitative analyses and contains:

- measured values processing

- chemical equilibria and titrimetric analysis

- basic isolation - and separation methodology

- basic absorption and emission spectroscopy

- pH electrode

Instruction

The teaching is given as lectures, seminars and laboratory sessions.

Compulsory parts of the course:

All laboratory elements.

Assessment

Examination is organised during the course and at the end of the course. Laboratory exercises are presented both orally and in writing. A chance to finalise a failed laboratory course can be given only at the next course occasion and only in case of a vacancy. For passed in the course, passed laboratory course (examination code) and passed examination (examination code) are required.