Genome Analysis

10 credits

Syllabus, Master's level, 1MB462

Education cycle
Second cycle
Main field(s) of study and in-depth level
Bioinformatics A1F, Technology A1F
Grading system
Fail (U), Pass (3), Pass with credit (4), Pass with distinction (5)
Finalised by
The Faculty Board of Science and Technology, 22 October 2021
Responsible department
Biology Education Centre

Entry requirements

120 credits. Participation in Molecular Evolution, and participation in course in programming 5 credits. Proficiency in English equivalent to the Swedish upper secondary course English 6.

Learning outcomes

On completion of the course, the student should be able to:

  • assemble raw sequence data to genome sequences and/or align them to existing reference genomes
  • analyse genome sequence data with regard to e.g. gene expressions, functional genomics, genome evolution and variation in populations
  • choose as well as apply methods in comparative genomics to analyse and draw conclusions about the biology and evolution of organisms
  • choose sequence technology and apply existing software for given biological problems in the area
  • critically analyse, evaluate and compile achieved results of genome analyses
  • discuss and present social, ethical and scientific aspects of genomics.


The course covers bioinformatics with a focus on analysis of genome sequence datasets, and contains the following components and aspects: Methods for large-scale sequencing and its different applications. Assembly of raw sequence data to complete genomes. Mapping of raw sequence data to existing reference genomes. Principles for annotation of genes and other biological information, annotation system, the problems with automatic annotation. Bioinformatic aspects on different methods to study the function, variation and evolution using large-scale sequencing of the genome. Bioinformatic aspects of metagenomics.


Lectures, seminars and computer exercises.


Written examination (5 credits). Participation in at least 80% of the seminars and presentation of computer exercises (5 credits).

If there are special reasons for doing so, an examiner may make an exception from the method of assessment indicated and allow a student to be assessed by another method. An example of special reasons might be a certificate regarding special pedagogical support from the disability coordinator of the university.