Entry requirements

Alt 1. 120 credits within the Master Programme in Molecular Biotechnology Engineering, including Biotechnical Methodology, Genomics and Bioinformatics, and Scientific Computing for Data Analysis. Proficiency in English equivalent to the Swedish upper secondary course English 6. Alt 2. 120 credits including Introduction to Bioinformatics, Computer Programming I, Introduction to Statistics for Life Sciences and Computational Methods for Scientific Applications. Proficiency in English equivalent to the Swedish upper secondary course English 6. Alt 3. 120 credits including Introduction to Bioinformatics and Introduction to Molecular Biology, Genetics and Evolution. Proficiency in English equivalent to the Swedish upper secondary course English 6.

Learning outcomes

On completion of the course, the student should be able to:

• account for and compare methods to study proteomics and metabolomics
• motivate the choice of methods and carry out basic experimental design for given biological and biomedical problems.
• carry out raw data analysis on collected data, such as identification of peptides / proteins / metabolites and comparison of proteomes and metabolomes between different groups of samples
• account for applications of proteomics and metabolomics in medicine and biology

Content

Introduction to proteomics and metabolomics. Methodologies and associated strategies for raw data analysis aimed at studying proteomics, especially mass spectrometry and antibody-based methods. Measurement methods with associated methods for raw data analysis designed to study the metabolome, especially mass spectrometry and NMR spectroscopy. Basic experimental design and strategies for comparative proteomics and metabolomics. Public database resources for data evaluation and interpretation of results. Examples of applications in medicine and biology.

Instruction

Lectures, seminars and computer labs.

Assessment

Written examination (3 credits), seminars and computer labs (2 credits). The final grade corresponds to a weighted average of the results of the different components of the course.

If there are special reasons for doing so, an examiner may make an exception from the method of assessment indicated and allow a student to be assessed by another method. An example of special reasons might be a certificate regarding special pedagogical support from the disability coordinator of the university.

Other directives

Cannot be included in a degree together with Proteomik och metabolomik, 5 hp (1MB448).