Biomarkers, Discovery and Validation, 7.5 credits

Academic year 2022/2023

  • Course code: 3MG028

    Spring 2023, 100%, Campus

    Start date: 27 April 2023

    End date: 4 June 2023

    Language of instruction: English

    Location: Uppsala

    Registration: Please contact the department.

Entry requirements: 180 credits in biology, bio-/medicine, biotechnology, pharmaceutical biosciences, medical science or equivalent education giving relevant knowledge in cell biology, genetics biochemistry and molecular biology. Proficiency in English equivalent to the Swedish upper secondary course English 6.

About the course

The course aims to provide an insight into the current knowledge, future potential use and development of biomarkers as both prognostic and diagnostic tools in health care. Different types of biomarkers will be discussed as well as the methods for discovery and validation of protein biomarkers in serum. Biomarkers for different diseases will be treated, such as biomarkers for cancers, neurological and cardiovascular diseases. Biomarkers in disease epidemiology and pathology will be covered. Biobanking and ethical considerations will be discussed and current clinical methods and diagnostics will be illustrated. Current opinions and research findings of molecular biomarkers, as well as the development of novel methods and technologies, will be discussed. The Human Protein Atlas will be described and used in practical exercises, illustrating the discovery of biomarkers for different cancers and other diseases.

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