Entry requirements

60 credits in science/engineering including 10 credits organic chemistry.

Learning outcomes

On completion of the course the student shall be able to:

• identify and describe synthetical processes relevant to organic-chemical reactions and discuss the mechanisms of these reactions,
• identify and discuss stereochemical problems related to chemical transformations,
• predict the properties of organic compounds - including their reactivity - from their structure, discuss how these properties may influence environmental and economical decisions,
• search information about, plan and carry out fundamental organic transformations aimed at solving organic-synthetic problems,
• carry out simple risk assessments and in-session laboratory documentation and account for the contents and results of laboratory sessions in oral/written forms.

Content

Organic-chemical reactions of industrially and biochemically relevant compound classes: Arenes, esters, alcohols, aldols, carbohydrates, lipids, amino acids, peptides and nucleic acids. Reaction mechanisms to build/degrade carbon compounds. Examples for common reagent within synthetic chemistry (oxidation, reduction, Lewis acids and Lewis bases, Grignard reagents, organolithium reagents). Mechanisms for catalytic reactions: acid-base catalysis, enzymatic catalysis, metal catalysis (also in biological systems). Organic-chemical reactions in water. Comparison between synthesis in biological systems and industrial synthesis. Overview of spectroscopic methods in organic chemistry (UV, IR, MS, NMR). Risk, safety, economical and environmental issues connected to laboratory work.

Instruction

Lectures, problem solving sessions, seminars and laboratory work.

Assessment

Written examination (6 credits). Laboratory sessions (4 credits). The final grade is a weighted sum of the results of the written examination and the laboratory sessions.

If there are special reasons for doing so, an examiner may make an exception from the method of assessment indicated and allow a student to be assessed by another method. An example of special reasons might be a certificate regarding special pedagogical support from the disability coordinator of the university.

Other directives

Cannot be included in a degree together with either of the courses 1KB407 Synthetic Organic Chemistry or 1KB419 Synthetic Organic Chemistry or 1KB420 (Organic Chemistry II).